Drug

Rifabutin

94 flagged reaction(s) · 2,455 total co-reports · max PRR 49.2

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Drug Resistance	161	49.2	52.3	signal
2	Uveitis	61	35.4	36.2	signal
3	Drug Level Decreased	41	31.4	31.9	signal
4	Tuberculosis	50	30.4	31.0	signal
5	Drug Reaction With Eosinophilia And Systemic Symptoms	82	25.1	25.9	signal
6	Nephropathy Toxic	26	18.2	18.4	signal
7	Hepatotoxicity	50	17.6	17.9	signal
8	Acute Hepatic Failure	30	17.2	17.4	signal
9	Lymphopenia	27	15.0	15.1	signal
10	Pulmonary Mass	26	13.7	13.8	signal
11	Drug Interaction	263	12.9	14.2	signal
12	Electrocardiogram Qt Prolonged	52	11.3	11.5	signal
13	Deafness	37	11.0	11.2	signal
14	Drug Intolerance	128	10.4	10.9	signal
15	Hepatic Cytolysis	16	10.2	10.3	signal
16	Leukopenia	64	10.0	10.2	signal
17	Malnutrition	14	9.8	9.9	signal
18	Cytopenia	15	9.8	9.8	signal
19	Pancytopenia	69	9.7	9.9	signal
20	Renal Tubular Necrosis	12	9.5	9.6	signal
21	Hepatomegaly	12	9.5	9.5	signal
22	Haemoptysis	33	9.2	9.3	signal
23	Hypercalcaemia	14	8.9	8.9	signal
24	Cholestasis	21	8.6	8.6	signal
25	Treatment Failure	83	7.9	8.1	signal
26	Drug Level Increased	16	7.5	7.6	signal
27	Drug-induced Liver Injury	29	7.3	7.4	signal
28	Adrenal Insufficiency	11	7.2	7.2	signal
29	Rash Maculo-papular	20	7.0	7.1	signal
30	Bone Marrow Failure	18	6.9	6.9	signal
31	Neutropenia	119	6.9	7.1	signal
32	Hyperbilirubinaemia	9	6.8	6.8	signal
33	Drug Eruption	15	6.6	6.7	signal
34	Chromaturia	18	6.2	6.3	signal
35	Osteomyelitis	14	6.0	6.1	signal
36	Anorexia	10	6.0	6.0	signal
37	Sputum Discoloured	7	5.8	5.8	signal
38	Hepatic Function Abnormal	26	5.5	5.5	signal
39	Drug Ineffective For Unapproved Indication	39	5.5	5.5	signal
40	Oral Candidiasis	9	5.4	5.4	signal
41	Ear Discomfort	7	5.3	5.3	signal
42	Sars-cov-2 Test Positive	9	5.3	5.3	signal
43	Hepatitis	17	5.2	5.2	signal
44	Lymphadenopathy	23	5.1	5.1	signal
45	Secretion Discharge	8	5.1	5.1	signal
46	Ascites	19	5.0	5.1	signal
47	Personality Change	6	5.0	5.0	signal
48	Vitreous Floaters	6	4.8	4.8	signal
49	Splenomegaly	7	4.7	4.7	signal
50	Emphysema	6	4.6	4.6	signal
51	Transaminases Increased	13	4.6	4.6	signal
52	Device Related Infection	9	4.5	4.6	signal
53	Thrombocytopenia	65	4.5	4.6	signal
54	Petechiae	6	4.5	4.5	signal
55	Night Sweats	18	4.4	4.4	signal
56	Renal Failure Acute	24	4.3	4.4	signal
57	Photosensitivity Reaction	9	4.3	4.3	signal
58	Tinnitus	25	4.2	4.3	signal
59	Multiple Organ Dysfunction Syndrome	15	4.2	4.2	signal
60	Myelosuppression	18	4.1	4.1	signal
61	Sinus Congestion	7	4.0	4.0	signal
62	Lymphoma	8	4.0	4.0	signal
63	Neuropathy Peripheral	48	4.0	4.0	signal
64	Disease Recurrence	24	3.9	3.9	signal
65	Helicobacter Infection	5	3.8	3.8	signal
66	Jaundice	13	3.8	3.8	signal
67	Hallucination, Visual	10	3.7	3.7	signal
68	Economic Problem	7	3.5	3.5	signal
69	Gamma-glutamyltransferase Increased	10	3.5	3.5	signal
70	Agranulocytosis	8	3.4	3.4	signal
71	Aphonia	6	3.4	3.4	signal
72	Hepatic Encephalopathy	4	3.3	3.3	signal
73	Treatment Noncompliance	23	3.3	3.3	signal
74	Bronchospasm	6	3.3	3.3	signal
75	Pharyngeal Swelling	4	3.3	3.3	signal
76	Anhedonia	11	3.2	3.2	signal
77	Stevens-johnson Syndrome	9	3.2	3.2	signal
78	Disease Progression	47	3.1	3.1	signal
79	Blood Triglycerides Increased	7	3.1	3.1	signal
80	Hallucination, Auditory	6	2.9	2.9	signal
81	Therapy Interrupted	26	2.9	3.0	signal
82	Toxicity To Various Agents	60	2.8	2.8	signal
83	Rebound Effect	4	2.8	2.8	no signal
84	Eosinophilia	6	2.7	2.7	signal
85	Grand Mal Convulsion	3	2.5	2.5	no signal
86	Cytomegalovirus Infection	5	2.3	2.3	no signal
87	Toxic Skin Eruption	3	2.3	2.3	no signal
88	Skeletal Injury	3	2.2	2.2	no signal
89	Hepatocellular Injury	4	2.2	2.2	no signal
90	Hepatitis C	3	1.9	1.9	no signal
91	Accidental Underdose	3	1.6	1.6	no signal
92	Drug Effective For Unapproved Indication	6	1.6	1.6	no signal
93	Bone Density Decreased	6	1.5	1.5	no signal
94	Drug Dose Omission By Device	3	0.3	0.3	no signal