Drug

Rilonacept

30 flagged reaction(s) · 1,088 total co-reports · max PRR 94.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Pericarditis	84	94.8	102.3	signal
2	Injection Site Rash	65	40.1	42.6	signal
3	Injection Site Warmth	27	24.6	25.1	signal
4	Injection Site Discomfort	12	21.8	22.0	signal
5	Injection Site Irritation	14	20.7	21.0	signal
6	Injection Site Erythema	132	20.0	22.6	signal
7	Injection Site Mass	39	19.8	20.5	signal
8	Injection Site Pruritus	68	19.1	20.3	signal
9	Injection Site Reaction	58	15.8	16.6	signal
10	Product Complaint	20	15.0	15.3	signal
11	Drug Effect Less Than Expected	11	14.6	14.7	signal
12	Injection Site Urticaria	18	13.9	14.1	signal
13	Injection Site Induration	9	13.0	13.1	signal
14	Injection Site Swelling	50	12.4	12.9	signal
15	Pericardial Effusion	15	12.2	12.4	signal
16	Chest Pain	115	11.6	12.8	signal
17	Injection Site Haemorrhage	39	9.2	9.5	signal
18	Chest Discomfort	50	9.2	9.6	signal
19	Skin Reaction	6	8.0	8.0	signal
20	Therapy Change	4	7.8	7.8	signal
21	Injection Site Discolouration	5	7.5	7.6	signal
22	Sars-cov-2 Test Positive	5	7.0	7.0	signal
23	Product Dose Omission Issue	103	6.8	7.4	signal
24	Cytomegalovirus Infection	6	6.7	6.8	signal
25	Drug Reaction With Eosinophilia And Systemic Symptoms	8	5.9	5.9	signal
26	Injection Site Bruising	24	5.7	5.8	signal
27	Pregnancy	6	5.5	5.6	signal
28	Injection Site Pain	87	5.4	5.7	signal
29	Therapeutic Response Shortened	5	2.9	2.9	signal
30	Product Preparation Error	3	2.7	2.7	no signal