OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Rituximab-pvvr

334 flagged reaction(s) · 18,658 total co-reports · max PRR 43.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Blood Pressure Fluctuation 252 43.8 46.0 signal
2 Intentional Product Use Issue 639 30.3 34.5 signal
3 Throat Irritation 313 29.2 31.0 signal
4 Blood Pressure Systolic Increased 134 28.5 29.2 signal
5 Poor Venous Access 65 26.2 26.5 signal
6 Pharyngeal Swelling 41 17.8 17.9 signal
7 Throat Tightness 101 15.5 15.8 signal
8 Incorrect Product Administration Duration 71 14.5 14.7 signal
9 Vasculitis 39 13.9 14.0 signal
10 Pulmonary Fibrosis 61 13.2 13.4 signal
11 Drug Effective For Unapproved Indication 89 12.6 12.8 signal
12 Heart Rate Irregular 66 12.0 12.2 signal
13 Heart Rate Decreased 99 11.6 11.8 signal
14 Infusion Related Reaction 185 11.6 12.0 signal
15 Oxygen Saturation Decreased 156 11.6 11.9 signal
16 C-reactive Protein Increased 93 10.6 10.8 signal
17 Off Label Use 2,180 10.4 17.5 signal
18 Body Temperature Decreased 24 10.0 10.1 signal
19 Therapeutic Response Shortened 76 9.9 10.0 signal
20 Red Blood Cell Sedimentation Rate Increased 26 9.7 9.8 signal
21 Cataract 135 9.4 9.7 signal
22 Dry Throat 23 9.4 9.4 signal
23 Joint Range Of Motion Decreased 30 9.3 9.4 signal
24 Paraesthesia Oral 32 9.2 9.3 signal
25 Tooth Extraction 27 9.0 9.0 signal
26 Ear Discomfort 21 8.5 8.5 signal
27 Condition Aggravated 613 8.4 9.4 signal
28 Covid-19 358 8.4 8.9 signal
29 Tooth Infection 26 8.2 8.2 signal
30 Inappropriate Schedule Of Product Administration 345 8.1 8.6 signal
31 Hip Arthroplasty 29 7.9 8.0 signal
32 Lymphoma 28 7.5 7.5 signal
33 Infusion Site Pain 23 7.5 7.5 signal
34 Feeling Cold 50 7.4 7.5 signal
35 Localised Infection 42 7.2 7.2 signal
36 Knee Arthroplasty 35 7.0 7.0 signal
37 Synovitis 30 6.9 6.9 signal
38 Heart Rate Increased 164 6.9 7.1 signal
39 Foot Deformity 18 6.7 6.7 signal
40 Covid-19 Pneumonia 19 6.6 6.6 signal
41 Blood Pressure Increased 244 6.6 6.9 signal
42 Immunodeficiency 23 6.5 6.5 signal
43 Pulmonary Mass 23 6.4 6.4 signal
44 Knee Operation 15 6.4 6.4 signal
45 Tooth Fracture 17 6.4 6.4 signal
46 Chills 178 6.3 6.5 signal
47 Feeling Hot 90 6.1 6.2 signal
48 Proteinuria 27 5.9 6.0 signal
49 Wrist Fracture 17 5.9 5.9 signal
50 Lung Disorder 69 5.8 5.9 signal
51 Joint Injury 30 5.8 5.8 signal
52 Pallor 38 5.8 5.8 signal
53 Oropharyngeal Pain 126 5.6 5.8 signal
54 Interstitial Lung Disease 65 5.6 5.6 signal
55 Sneezing 30 5.6 5.6 signal
56 Eye Infection 15 5.5 5.6 signal
57 Chest Discomfort 136 5.5 5.6 signal
58 Body Temperature Increased 27 5.5 5.5 signal
59 Clostridium Difficile Colitis 14 5.5 5.5 signal
60 Brain Fog 19 5.4 5.4 signal
61 Limb Injury 35 5.4 5.4 signal
62 Wound Infection 14 5.3 5.3 signal
63 Nasal Congestion 75 5.3 5.4 signal
64 Tooth Disorder 28 5.2 5.2 signal
65 Product Use Issue 233 5.2 5.4 signal
66 Cystitis 39 5.1 5.1 signal
67 Immune System Disorder 16 5.0 5.0 signal
68 Bladder Disorder 12 5.0 5.0 signal
69 Spinal Fracture 24 5.0 5.0 signal
70 Hernia 23 4.9 5.0 signal
71 Blood Iron Decreased 14 4.9 4.9 signal
72 Anaphylactic Reaction 65 4.9 5.0 signal
73 Sputum Discoloured 11 4.8 4.8 signal
74 Productive Cough 55 4.8 4.9 signal
75 Foot Fracture 22 4.8 4.8 signal
76 Rheumatoid Arthritis 130 4.8 4.9 signal
77 Cyst 14 4.7 4.7 signal
78 Ligament Sprain 11 4.6 4.6 signal
79 Sinus Congestion 15 4.6 4.6 signal
80 Hypertension 235 4.6 4.8 signal
81 Illness 109 4.5 4.6 signal
82 Pericarditis 18 4.5 4.5 signal
83 Renal Disorder 50 4.4 4.5 signal
84 Clostridium Difficile Infection 23 4.4 4.4 signal
85 Cholecystectomy 12 4.4 4.4 signal
86 Ear Infection 28 4.4 4.4 signal
87 Inflammation 54 4.4 4.4 signal
88 Eye Disorder 34 4.3 4.3 signal
89 Eye Pruritus 34 4.3 4.3 signal
90 Loss Of Personal Independence In Daily Activities 49 4.3 4.3 signal
91 Osteoarthritis 43 4.2 4.2 signal
92 Cough 283 4.2 4.4 signal
93 Cytopenia 12 4.2 4.2 signal
94 Flushing 102 4.1 4.2 signal
95 Rhinorrhoea 64 4.1 4.2 signal
96 Emphysema 10 4.1 4.1 signal
97 Lower Respiratory Tract Infection 44 4.0 4.0 signal
98 Systemic Lupus Erythematosus 34 4.0 4.0 signal
99 Basal Cell Carcinoma 15 4.0 4.0 signal
100 Sinus Disorder 19 4.0 4.0 signal
101 Joint Dislocation 10 3.9 3.9 signal
102 Nasopharyngitis 173 3.9 4.0 signal
103 Skin Laceration 10 3.8 3.8 signal
104 Deafness 24 3.8 3.8 signal
105 Bacterial Infection 17 3.8 3.8 signal
106 Spinal Operation 11 3.8 3.8 signal
107 Secretion Discharge 11 3.7 3.7 signal
108 Pruritus 335 3.7 3.9 signal
109 Muscle Atrophy 11 3.6 3.6 signal
110 Ear Pain 17 3.6 3.6 signal
111 Lacrimation Increased 26 3.6 3.6 signal
112 Wound 24 3.6 3.6 signal
113 Erythema 177 3.6 3.7 signal
114 Disease Recurrence 41 3.6 3.6 signal
115 Dysphonia 50 3.5 3.6 signal
116 Mouth Ulceration 18 3.5 3.6 signal
117 Diarrhoea Haemorrhagic 8 3.5 3.5 signal
118 Pneumonitis 23 3.5 3.5 signal
119 Eye Inflammation 8 3.5 3.5 signal
120 Pulmonary Oedema 38 3.5 3.5 signal
121 Sinusitis 87 3.5 3.5 signal
122 Drug Ineffective For Unapproved Indication 47 3.5 3.5 signal
123 Nodule 11 3.5 3.5 signal
124 Ankle Fracture 13 3.5 3.5 signal
125 Back Injury 9 3.4 3.4 signal
126 Dyspnoea Exertional 31 3.4 3.4 signal
127 Restless Legs Syndrome 15 3.4 3.4 signal
128 Therapeutic Product Effect Incomplete 58 3.4 3.4 signal
129 Herpes Zoster 47 3.4 3.4 signal
130 Rash Erythematous 38 3.4 3.4 signal
131 Musculoskeletal Stiffness 71 3.4 3.4 signal
132 Skin Infection 9 3.3 3.3 signal
133 Swollen Tongue 25 3.3 3.3 signal
134 Hypoaesthesia Oral 12 3.3 3.3 signal
135 Pneumonia 254 3.3 3.4 signal
136 Carpal Tunnel Syndrome 11 3.2 3.2 signal
137 Rib Fracture 16 3.2 3.2 signal
138 Scratch 8 3.2 3.2 signal
139 Face Oedema 13 3.2 3.2 signal
140 Kidney Infection 15 3.2 3.2 signal
141 Agranulocytosis 14 3.1 3.1 signal
142 Renal Pain 8 3.1 3.1 signal
143 Pulmonary Congestion 10 3.1 3.1 signal
144 Tachycardia 67 3.1 3.2 signal
145 Viral Infection 25 3.1 3.1 signal
146 Upper Limb Fracture 15 3.1 3.1 signal
147 Bursitis 9 3.1 3.1 signal
148 Infection 107 3.1 3.1 signal
149 Skin Lesion 20 3.0 3.0 signal
150 Pulmonary Thrombosis 8 3.0 3.0 signal
151 Dizziness Postural 7 3.0 3.0 signal
152 Peripheral Coldness 10 3.0 3.0 signal
153 Blood Pressure Decreased 48 3.0 3.0 signal
154 Nephrolithiasis 33 3.0 3.0 signal
155 Toothache 13 3.0 3.0 signal
156 Product Prescribing Error 17 3.0 3.0 signal
157 Aphonia 10 3.0 3.0 signal
158 Hot Flush 54 3.0 3.0 signal
159 Blindness 29 2.9 3.0 signal
160 Tremor 117 2.9 3.0 signal
161 Bronchospasm 10 2.9 2.9 signal
162 Rotator Cuff Syndrome 9 2.9 2.9 signal
163 Influenza 78 2.9 2.9 signal
164 Sciatica 11 2.9 2.9 signal
165 Wheezing 41 2.9 2.9 signal
166 Muscle Twitching 16 2.9 2.9 signal
167 Malaise 304 2.9 3.0 signal
168 Joint Swelling 83 2.9 2.9 signal
169 Hip Fracture 22 2.8 2.8 signal
170 Cytokine Release Syndrome 13 2.8 2.8 signal
171 Head Discomfort 12 2.8 2.8 signal
172 Lymphocyte Count Decreased 12 2.8 2.8 signal
173 Weight Fluctuation 7 2.8 2.8 signal
174 Gait Inability 22 2.8 2.8 signal
175 Hypoxia 23 2.7 2.7 signal
176 Respiratory Tract Infection 17 2.7 2.7 signal
177 Pericardial Effusion 15 2.7 2.7 signal
178 Diverticulitis 18 2.7 2.7 signal
179 Dyspnoea 368 2.7 2.8 signal
180 Skin Cancer 14 2.7 2.7 signal
181 Generalised Oedema 8 2.7 2.7 signal
182 Pharyngitis Streptococcal 7 2.7 2.7 signal
183 Intervertebral Disc Degeneration 6 2.7 2.7 signal
184 Blood Test Abnormal 9 2.7 2.7 signal
185 Cyanosis 10 2.6 2.6 signal
186 Respiratory Tract Congestion 10 2.6 2.6 signal
187 Ulcer 10 2.6 2.6 signal
188 Restlessness 23 2.6 2.6 signal
189 Arthropathy 35 2.6 2.6 signal
190 Obstructive Airways Disorder 7 2.6 2.6 signal
191 Gastrointestinal Disorder 55 2.6 2.6 signal
192 Myocarditis 7 2.6 2.6 signal
193 Decreased Immune Responsiveness 6 2.5 2.5 signal
194 Limb Discomfort 19 2.5 2.5 signal
195 Poor Quality Sleep 13 2.5 2.5 signal
196 Blood Pressure Abnormal 12 2.5 2.5 signal
197 Dysphagia 57 2.5 2.5 signal
198 Fungal Infection 20 2.5 2.5 signal
199 White Blood Cell Count Increased 23 2.5 2.5 signal
200 Malignant Melanoma 8 2.5 2.5 signal
201 Tachypnoea 8 2.4 2.4 signal
202 Urinary Tract Infection 100 2.4 2.5 signal
203 Mobility Decreased 42 2.4 2.4 signal
204 Neutrophil Count Increased 6 2.4 2.4 no signal
205 Weight Decreased 162 2.4 2.4 signal
206 Diplopia 15 2.4 2.4 signal
207 Peripheral Swelling 88 2.4 2.4 signal
208 Post Procedural Complication 11 2.4 2.4 signal
209 Mass 8 2.4 2.4 signal
210 Skin Reaction 8 2.4 2.4 signal
211 Eye Swelling 21 2.4 2.4 signal
212 Pneumothorax 9 2.3 2.4 signal
213 Respiratory Disorder 17 2.3 2.3 signal
214 Cold Sweat 10 2.3 2.3 signal
215 Dialysis 8 2.3 2.3 signal
216 Eating Disorder 12 2.3 2.3 signal
217 Gallbladder Disorder 10 2.3 2.3 signal
218 Urticaria 92 2.3 2.3 signal
219 Ocular Discomfort 6 2.3 2.3 no signal
220 Product Administration Error 11 2.3 2.3 signal
221 Rash Macular 19 2.3 2.3 signal
222 Asthenia 205 2.3 2.3 signal
223 Nerve Compression 5 2.2 2.2 no signal
224 Increased Tendency To Bruise 5 2.2 2.2 no signal
225 Weight Increased 120 2.2 2.3 signal
226 Haemoptysis 15 2.2 2.2 signal
227 Arthralgia 222 2.2 2.3 signal
228 Diabetes Mellitus 41 2.2 2.2 signal
229 Cellulitis 27 2.2 2.2 signal
230 Headache 335 2.2 2.3 signal
231 Hand Deformity 7 2.2 2.2 no signal
232 Oral Pain 12 2.2 2.2 signal
233 Balance Disorder 46 2.2 2.2 signal
234 Burning Sensation 37 2.2 2.2 signal
235 Bradycardia 28 2.2 2.2 signal
236 Neoplasm Malignant 35 2.2 2.2 signal
237 Internal Haemorrhage 6 2.2 2.2 no signal
238 Musculoskeletal Discomfort 9 2.2 2.2 signal
239 Swelling Face 34 2.2 2.2 signal
240 Autoimmune Disorder 5 2.2 2.2 no signal
241 Palpitations 61 2.2 2.2 signal
242 Thrombosis 42 2.2 2.2 signal
243 Glaucoma 10 2.1 2.2 signal
244 Neck Pain 29 2.1 2.2 signal
245 Chronic Obstructive Pulmonary Disease 27 2.1 2.1 signal
246 Impaired Healing 17 2.1 2.1 signal
247 Retching 11 2.1 2.1 signal
248 Fatigue 400 2.1 2.2 signal
249 Nervousness 27 2.1 2.1 signal
250 Ocular Hyperaemia 24 2.1 2.1 signal
251 Spinal Pain 6 2.1 2.1 no signal
252 Therapeutic Response Unexpected 23 2.1 2.1 signal
253 Haemoglobin Decreased 52 2.1 2.1 signal
254 Colitis 19 2.1 2.1 signal
255 Type 2 Diabetes Mellitus 17 2.1 2.1 signal
256 Feeding Disorder 10 2.1 2.1 signal
257 Gastroenteritis Viral 9 2.1 2.1 no signal
258 Night Sweats 16 2.1 2.1 signal
259 Glomerular Filtration Rate Decreased 6 2.0 2.1 no signal
260 Fall 164 2.0 2.1 signal
261 Hepatic Cytolysis 6 2.0 2.0 no signal
262 Back Pain 114 2.0 2.1 signal
263 Hyperhidrosis 63 2.0 2.0 signal
264 Pain 297 2.0 2.1 no signal
265 Pemphigus 6 2.0 2.0 no signal
266 Paraesthesia 76 2.0 2.0 no signal
267 Dry Eye 23 2.0 2.0 no signal
268 Irritable Bowel Syndrome 10 1.9 1.9 no signal
269 Pain In Extremity 138 1.9 2.0 no signal
270 Dementia 13 1.9 1.9 no signal
271 Drug Hypersensitivity 90 1.9 1.9 no signal
272 Oral Herpes 9 1.9 1.9 no signal
273 Discomfort 28 1.9 1.9 no signal
274 Laryngitis 5 1.9 1.9 no signal
275 Lung Neoplasm Malignant 19 1.9 1.9 no signal
276 Platelet Count Increased 6 1.9 1.9 no signal
277 Thyroid Disorder 7 1.9 1.9 no signal
278 Thirst 8 1.9 1.9 no signal
279 Influenza Like Illness 37 1.9 1.9 no signal
280 Rash Pruritic 24 1.8 1.8 no signal
281 Uveitis 6 1.8 1.8 no signal
282 Dysstasia 13 1.8 1.8 no signal
283 Scab 5 1.8 1.8 no signal
284 Death 375 1.8 1.9 no signal
285 Bone Disorder 8 1.8 1.8 no signal
286 Procedural Pain 12 1.8 1.8 no signal
287 Squamous Cell Carcinoma 4 1.8 1.8 no signal
288 Lip Swelling 14 1.7 1.7 no signal
289 Polyneuropathy 5 1.7 1.7 no signal
290 Blood Urine Present 8 1.7 1.7 no signal
291 Choking 8 1.7 1.7 no signal
292 Vitreous Floaters 4 1.7 1.7 no signal
293 Respiratory Depression 5 1.7 1.7 no signal
294 Coeliac Disease 4 1.7 1.7 no signal
295 Injection Site Extravasation 5 1.7 1.7 no signal
296 Neoplasm Progression 14 1.7 1.7 no signal
297 Hypoacusis 17 1.6 1.6 no signal
298 Fluid Retention 20 1.6 1.6 no signal
299 Anaphylactic Shock 10 1.6 1.6 no signal
300 Disease Progression 46 1.6 1.6 no signal
301 Angina Pectoris 11 1.6 1.6 no signal
302 Breast Pain 4 1.6 1.6 no signal
303 Fracture 7 1.5 1.5 no signal
304 Musculoskeletal Disorder 7 1.5 1.5 no signal
305 Cardiac Disorder 34 1.5 1.5 no signal
306 Lymphopenia 5 1.5 1.5 no signal
307 Multiple Sclerosis 17 1.5 1.5 no signal
308 Impaired Driving Ability 4 1.5 1.5 no signal
309 Paranoia 6 1.4 1.4 no signal
310 Anosmia 5 1.4 1.4 no signal
311 Product Prescribing Issue 7 1.4 1.4 no signal
312 Therapeutic Product Effect Decreased 15 1.4 1.4 no signal
313 Thyroid Cancer 4 1.4 1.4 no signal
314 Brain Neoplasm 3 1.4 1.4 no signal
315 Tendon Rupture 4 1.3 1.3 no signal
316 Inflammatory Bowel Disease 3 1.3 1.3 no signal
317 Mania 5 1.3 1.3 no signal
318 Ovarian Cyst 3 1.2 1.2 no signal
319 Abortion Spontaneous 12 1.2 1.2 no signal
320 Poor Quality Product Administered 3 1.2 1.2 no signal
321 Femur Fracture 9 1.2 1.2 no signal
322 Product Dispensing Error 6 1.1 1.1 no signal
323 Pelvic Pain 5 1.1 1.1 no signal
324 Fistula 3 1.1 1.1 no signal
325 Osteonecrosis 8 1.0 1.0 no signal
326 Blood Glucose Increased 40 0.9 0.9 no signal
327 Hepatic Cancer 5 0.9 0.9 no signal
328 Incorrect Dose Administered 46 0.8 0.8 no signal
329 Pancreatic Carcinoma 4 0.6 0.6 no signal
330 Breast Cancer 12 0.5 0.5 no signal
331 Myelosuppression 4 0.5 0.5 no signal
332 Breast Cancer Female 3 0.5 0.5 no signal
333 Prostate Cancer 9 0.5 0.5 no signal
334 Bladder Cancer 4 0.3 0.3 no signal