OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Sennosides A And B

113 flagged reaction(s) · 3,363 total co-reports · max PRR 70.6
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Vasculitis 62 70.6 73.4 signal
2 Obstructive Airways Disorder 42 49.9 51.2 signal
3 Coeliac Disease 33 44.5 45.5 signal
4 Immunodeficiency 47 42.3 43.5 signal
5 Full Blood Count Abnormal 33 41.5 42.3 signal
6 Bursitis 35 38.4 39.3 signal
7 Subarachnoid Haemorrhage 27 35.0 35.6 signal
8 Haemoptysis 70 33.1 34.6 signal
9 Myocardial Ischaemia 28 32.3 32.9 signal
10 Prescribed Overdose 46 31.5 32.4 signal
11 Pulmonary Fibrosis 45 31.2 32.0 signal
12 Cardiomegaly 29 30.9 31.5 signal
13 Sleep Disorder Due To A General Medical Condition 37 30.3 31.0 signal
14 Pneumonia Aspiration 49 26.0 26.8 signal
15 Ventricular Tachycardia 32 25.5 26.0 signal
16 Anosmia 26 23.7 24.1 signal
17 Arteriosclerosis 16 22.4 22.7 signal
18 Drug Level Increased 27 21.6 21.9 signal
19 Pericarditis 26 20.6 21.0 signal
20 Decreased Immune Responsiveness 15 20.3 20.5 signal
21 Contraindicated Product Administered 42 18.4 18.9 signal
22 Nodule 17 17.2 17.4 signal
23 Body Temperature Decreased 12 16.0 16.1 signal
24 Ascites 35 15.7 16.1 signal
25 Productive Cough 56 15.6 16.2 signal
26 Hypothyroidism 37 15.4 15.7 signal
27 Febrile Neutropenia 76 15.2 15.9 signal
28 Muscle Twitching 26 14.9 15.1 signal
29 Infusion Related Reaction 71 14.2 14.8 signal
30 Upper Respiratory Tract Infection 49 14.0 14.4 signal
31 Cytokine Release Syndrome 20 13.9 14.0 signal
32 Diplopia 27 13.7 14.0 signal
33 Aspiration 11 13.4 13.5 signal
34 Rash Erythematous 45 12.7 13.0 signal
35 Pain Of Skin 25 12.2 12.4 signal
36 Fluid Retention 47 12.2 12.6 signal
37 Exposure During Pregnancy 56 11.9 12.3 signal
38 Oesophageal Carcinoma 27 11.9 12.1 signal
39 Pleural Effusion 54 11.7 12.1 signal
40 Inappropriate Antidiuretic Hormone Secretion 9 11.7 11.7 signal
41 Cognitive Disorder 41 11.6 11.9 signal
42 Iron Deficiency Anaemia 8 11.5 11.6 signal
43 Wheezing 51 11.4 11.7 signal
44 Transient Ischaemic Attack 29 11.3 11.5 signal
45 Interstitial Lung Disease 41 11.2 11.5 signal
46 Lip Swelling 28 11.1 11.3 signal
47 Covid-19 Pneumonia 10 11.1 11.2 signal
48 Lower Respiratory Tract Infection 38 11.1 11.3 signal
49 Intentional Product Misuse 72 11.0 11.4 signal
50 Hypoxia 29 10.9 11.1 signal
51 Eye Pruritus 27 10.8 11.0 signal
52 Blood Pressure Systolic Increased 16 10.8 10.9 signal
53 Dental Caries 9 10.8 10.8 signal
54 Pneumocystis Jirovecii Pneumonia 8 10.6 10.6 signal
55 Blood Calcium Decreased 9 10.5 10.6 signal
56 Lung Disorder 38 10.3 10.5 signal
57 Asthma 85 10.0 10.5 signal
58 Hepatic Enzyme Increased 51 9.9 10.2 signal
59 Orthostatic Hypotension 13 9.8 9.9 signal
60 Loss Of Personal Independence In Daily Activities 35 9.7 9.9 signal
61 Hypoglycaemia 35 9.5 9.7 signal
62 Incorrect Route Of Product Administration 12 9.4 9.5 signal
63 Blindness 29 9.4 9.6 signal
64 Therapeutic Product Effect Incomplete 50 9.3 9.6 signal
65 Adrenal Insufficiency 8 8.8 8.9 signal
66 Constipation 142 8.7 9.4 signal
67 Hallucination 48 8.5 8.7 signal
68 Hyperhidrosis 82 8.4 8.8 signal
69 Sputum Discoloured 6 8.4 8.4 signal
70 Tinnitus 29 8.3 8.5 signal
71 Renal Impairment 52 8.2 8.5 signal
72 Hepatic Function Abnormal 23 8.2 8.3 signal
73 Angioedema 27 8.1 8.2 signal
74 Bladder Disorder 6 8.0 8.0 signal
75 Neutrophil Count Decreased 24 7.8 7.9 signal
76 Coma 27 7.5 7.6 signal
77 Thrombocytopenia 60 7.1 7.3 signal
78 Erythema Multiforme 5 7.1 7.1 signal
79 Colitis 20 7.0 7.1 signal
80 Treatment Failure 43 6.9 7.1 signal
81 Disturbance In Attention 28 6.8 6.9 signal
82 Retching 11 6.8 6.9 signal
83 Eosinophilia 9 6.8 6.8 signal
84 Altered State Of Consciousness 11 6.7 6.8 signal
85 Neuroleptic Malignant Syndrome 6 6.7 6.7 signal
86 Disseminated Intravascular Coagulation 7 6.5 6.6 signal
87 Hypothermia 5 6.5 6.5 signal
88 Subdural Haematoma 7 6.4 6.5 signal
89 Amnesia 30 6.1 6.2 signal
90 Joint Swelling 51 5.6 5.7 signal
91 Posterior Reversible Encephalopathy Syndrome 4 5.6 5.6 signal
92 Underdose 29 5.2 5.3 signal
93 Heart Rate Irregular 9 5.2 5.3 signal
94 Cardiac Failure Congestive 32 5.2 5.3 signal
95 Poor Venous Access 4 5.1 5.1 signal
96 Injection Site Induration 5 5.1 5.1 signal
97 Sedation 10 5.1 5.1 signal
98 Rheumatoid Arthritis 42 4.9 5.0 signal
99 Cytomegalovirus Infection 6 4.8 4.8 signal
100 Myelodysplastic Syndrome 5 4.6 4.6 signal
101 Neurotoxicity 6 4.6 4.6 signal
102 Psoriasis 44 4.4 4.5 signal
103 Drug Abuse 28 4.4 4.5 signal
104 Pemphigus 4 4.2 4.3 signal
105 Overdose 64 3.9 4.0 signal
106 Myelosuppression 10 3.9 3.9 signal
107 Diabetic Ketoacidosis 6 3.3 3.3 signal
108 Hepatitis C 3 3.2 3.2 no signal
109 Dry Skin 31 3.1 3.2 signal
110 Plasma Cell Myeloma 9 3.0 3.1 signal
111 Pancreatic Carcinoma 5 2.3 2.3 no signal
112 Device Breakage 3 1.0 1.0 no signal
113 Prostate Cancer 6 1.0 1.0 no signal