OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Skin Protectant

222 flagged reaction(s) · 8,872 total co-reports · max PRR 273.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Macular Degeneration 460 273.0 320.6 signal
2 Vaginal Discharge 148 101.6 106.7 signal
3 Paraesthesia Oral 198 94.9 101.4 signal
4 Oral Candidiasis 149 78.7 82.7 signal
5 Procedural Pain 190 47.0 50.0 signal
6 Frequent Bowel Movements 152 38.6 40.6 signal
7 Colitis 160 29.0 30.5 signal
8 Rectal Haemorrhage 162 25.6 27.0 signal
9 Colitis Ulcerative 153 23.4 24.6 signal
10 Therapeutic Product Effect Incomplete 222 21.4 23.0 signal
11 Infusion Related Reaction 206 21.3 22.7 signal
12 Haematochezia 171 21.2 22.3 signal
13 Accident 36 20.6 20.8 signal
14 Nephropathy 26 18.9 19.0 signal
15 Body Height Decreased 25 15.8 15.9 signal
16 Haemorrhoids 43 15.0 15.2 signal
17 Dyspepsia 210 14.6 15.6 signal
18 Body Temperature Increased 42 14.0 14.1 signal
19 Schizophrenia 23 12.9 13.0 signal
20 Bacteraemia 21 12.1 12.2 signal
21 Sciatica 28 12.0 12.1 signal
22 Obesity 28 11.9 12.0 signal
23 Joint Range Of Motion Decreased 23 11.7 11.8 signal
24 Malnutrition 19 11.6 11.7 signal
25 Febrile Neutropenia 113 11.6 12.0 signal
26 Pneumonia Aspiration 42 11.5 11.6 signal
27 Disseminated Intravascular Coagulation 23 11.1 11.2 signal
28 Cholelithiasis 51 10.6 10.7 signal
29 Hepatic Steatosis 28 10.2 10.3 signal
30 Synovitis 25 9.4 9.5 signal
31 Blood Bilirubin Increased 37 9.3 9.4 signal
32 Drug Eruption 24 9.3 9.3 signal
33 Foot Deformity 15 9.2 9.2 signal
34 Hepatotoxicity 29 8.9 9.0 signal
35 Ileus 16 8.8 8.9 signal
36 Limb Injury 34 8.5 8.6 signal
37 Anaemia 237 8.5 9.1 signal
38 Knee Arthroplasty 24 7.8 7.9 signal
39 Pyrexia 397 7.8 8.8 signal
40 Constipation 238 7.5 8.0 signal
41 Abdominal Pain 243 7.1 7.6 signal
42 Device Related Infection 16 7.1 7.1 signal
43 Clostridium Difficile Colitis 11 7.0 7.1 signal
44 Atelectasis 10 7.0 7.0 signal
45 Dermatitis 21 6.9 6.9 signal
46 Movement Disorder 32 6.7 6.8 signal
47 Joint Stiffness 26 6.7 6.8 signal
48 Arthropathy 55 6.7 6.8 signal
49 Septic Shock 42 6.6 6.7 signal
50 Electrolyte Imbalance 11 6.5 6.5 signal
51 Dysstasia 28 6.5 6.6 signal
52 Weight Decreased 266 6.5 7.0 signal
53 Erythema 190 6.3 6.6 signal
54 Covid-19 Pneumonia 11 6.3 6.3 signal
55 Hypoxia 32 6.2 6.3 signal
56 Skin Infection 10 6.1 6.1 signal
57 Iron Deficiency Anaemia 8 5.9 5.9 signal
58 Hepatic Enzyme Increased 58 5.8 5.9 signal
59 Arteriosclerosis 8 5.8 5.8 signal
60 Hepatic Function Abnormal 31 5.7 5.7 signal
61 Blood Lactate Dehydrogenase Increased 13 5.5 5.6 signal
62 Liver Disorder 36 5.5 5.6 signal
63 Skin Disorder 27 5.5 5.6 signal
64 Osteoporosis 33 5.4 5.5 signal
65 Scab 9 5.4 5.4 signal
66 Lymphocyte Count Decreased 14 5.4 5.4 signal
67 Cytokine Release Syndrome 15 5.4 5.4 signal
68 Lower Respiratory Tract Infection 35 5.3 5.3 signal
69 Bone Density Decreased 24 5.2 5.2 signal
70 Gastroenteritis 11 5.1 5.1 signal
71 Respiratory Failure 55 5.1 5.2 signal
72 Osteoarthritis 32 5.1 5.2 signal
73 Adrenal Insufficiency 9 5.1 5.1 signal
74 Erythema Multiforme 7 5.1 5.1 signal
75 Hepatic Encephalopathy 7 5.1 5.1 signal
76 Sepsis 82 5.0 5.1 signal
77 Supraventricular Tachycardia 7 5.0 5.0 signal
78 Oesophagitis 8 5.0 5.0 signal
79 Hypercalcaemia 9 5.0 5.0 signal
80 Pleural Effusion 44 4.9 5.0 signal
81 Psoriatic Arthropathy 29 4.9 4.9 signal
82 Hypokalaemia 33 4.9 4.9 signal
83 Stevens-johnson Syndrome 16 4.9 4.9 signal
84 Renal Tubular Necrosis 7 4.8 4.8 signal
85 Psychotic Disorder 21 4.8 4.9 signal
86 Malaise 311 4.8 5.2 signal
87 Dermatitis Contact 8 4.8 4.8 signal
88 Pneumothorax 11 4.7 4.7 signal
89 Neutrophil Count Decreased 28 4.7 4.7 signal
90 Respiratory Distress 19 4.7 4.7 signal
91 Hyperkalaemia 24 4.7 4.7 signal
92 Gastritis 18 4.7 4.7 signal
93 Palmar-plantar Erythrodysaesthesia Syndrome 16 4.7 4.7 signal
94 Cellulitis 34 4.6 4.6 signal
95 Metastases To Bone 11 4.6 4.6 signal
96 Interstitial Lung Disease 31 4.4 4.4 signal
97 Delirium 22 4.3 4.4 signal
98 Neutropenia 85 4.3 4.4 signal
99 Obstructive Airways Disorder 7 4.3 4.3 signal
100 Oral Pain 14 4.2 4.3 signal
101 Blood Potassium Increased 10 4.2 4.2 signal
102 Ascites 18 4.2 4.2 signal
103 Bedridden 8 4.1 4.2 signal
104 Pericardial Effusion 14 4.1 4.2 signal
105 Lung Neoplasm Malignant 25 4.1 4.1 signal
106 C-reactive Protein Increased 22 4.1 4.1 signal
107 Pulmonary Congestion 8 4.1 4.1 signal
108 Alanine Aminotransferase Increased 37 4.1 4.1 signal
109 Candida Infection 10 4.1 4.1 signal
110 Conjunctivitis 11 4.1 4.1 signal
111 Therapy Partial Responder 9 4.1 4.1 signal
112 Chronic Obstructive Pulmonary Disease 31 4.0 4.1 signal
113 Toxic Skin Eruption 6 4.0 4.0 signal
114 Hypophagia 15 4.0 4.0 signal
115 Tachypnoea 8 4.0 4.0 signal
116 Diabetes Mellitus 45 4.0 4.0 signal
117 Hyponatraemia 33 4.0 4.0 signal
118 Musculoskeletal Pain 31 4.0 4.0 signal
119 Gamma-glutamyltransferase Increased 13 4.0 4.0 signal
120 Acute Myeloid Leukaemia 9 3.9 3.9 signal
121 Gastrooesophageal Reflux Disease 46 3.9 3.9 signal
122 Urinary Retention 19 3.9 3.9 signal
123 Transfusion 6 3.9 3.9 signal
124 Hepatic Failure 17 3.8 3.8 signal
125 Pneumonitis 15 3.8 3.8 signal
126 Prescribed Underdose 11 3.7 3.8 signal
127 Flatulence 31 3.7 3.8 signal
128 Gastrointestinal Pain 6 3.7 3.7 signal
129 Red Blood Cell Sedimentation Rate Increased 6 3.7 3.7 signal
130 Bone Marrow Failure 11 3.7 3.7 signal
131 Cerebral Infarction 13 3.6 3.6 signal
132 Toxic Epidermal Necrolysis 8 3.6 3.6 signal
133 Skin Fissures 10 3.6 3.6 signal
134 Spinal Disorder 5 3.6 3.6 signal
135 Haematuria 18 3.6 3.6 signal
136 Wheezing 31 3.6 3.6 signal
137 Eating Disorder 11 3.5 3.5 signal
138 Pulmonary Oedema 23 3.5 3.5 signal
139 Pain 315 3.5 3.8 signal
140 Decreased Immune Responsiveness 5 3.5 3.5 signal
141 Product Administration Error 10 3.4 3.4 signal
142 Haemoptysis 14 3.4 3.4 signal
143 Pneumocystis Jirovecii Pneumonia 5 3.4 3.4 signal
144 Mucosal Inflammation 13 3.4 3.4 signal
145 Platelet Count Decreased 53 3.4 3.4 signal
146 Emphysema 5 3.4 3.4 signal
147 Inappropriate Antidiuretic Hormone Secretion 5 3.3 3.3 signal
148 Subarachnoid Haemorrhage 5 3.3 3.3 signal
149 Subdural Haematoma 7 3.3 3.3 signal
150 Poor Venous Access 5 3.3 3.3 signal
151 Proteinuria 9 3.2 3.3 signal
152 Immunodeficiency 7 3.2 3.2 signal
153 Eructation 9 3.2 3.2 signal
154 Dementia 13 3.2 3.2 signal
155 Tooth Infection 6 3.1 3.1 signal
156 International Normalised Ratio Increased 13 3.1 3.1 signal
157 Intentional Product Misuse 39 3.1 3.1 signal
158 Pancreatitis Acute 10 3.0 3.1 signal
159 Blood Creatine Phosphokinase Increased 13 3.0 3.0 signal
160 Cyanosis 7 3.0 3.0 signal
161 Acute Hepatic Failure 6 3.0 3.0 signal
162 Shock 10 3.0 3.0 signal
163 Herpes Zoster 25 3.0 3.0 signal
164 Drug Reaction With Eosinophilia And Systemic Symptoms 11 2.9 2.9 signal
165 Anaphylactic Shock 11 2.9 2.9 signal
166 Blood Test Abnormal 6 2.9 2.9 signal
167 Drug Ineffective 559 2.9 3.3 signal
168 Posterior Reversible Encephalopathy Syndrome 4 2.9 2.9 no signal
169 Blood Urine Present 8 2.9 2.9 signal
170 Cytopenia 5 2.8 2.8 signal
171 Altered State Of Consciousness 9 2.8 2.8 signal
172 Impaired Quality Of Life 6 2.8 2.8 signal
173 Melaena 9 2.8 2.8 signal
174 Tooth Extraction 5 2.7 2.7 no signal
175 Hypothermia 4 2.7 2.7 no signal
176 Sluggishness 4 2.7 2.7 no signal
177 Hypoglycaemia 19 2.7 2.7 signal
178 Sars-cov-2 Test Positive 5 2.5 2.5 no signal
179 Breast Cancer Metastatic 4 2.5 2.5 no signal
180 Serotonin Syndrome 7 2.5 2.5 signal
181 Cerebral Haemorrhage 13 2.5 2.5 signal
182 Cytomegalovirus Infection 6 2.5 2.5 no signal
183 Status Epilepticus 4 2.4 2.4 no signal
184 Internal Haemorrhage 4 2.4 2.4 no signal
185 Drug Abuse 29 2.4 2.4 signal
186 Metastases To Lung 4 2.4 2.4 no signal
187 Gastric Haemorrhage 4 2.3 2.3 no signal
188 Peritonitis 7 2.3 2.3 no signal
189 Eczema 17 2.3 2.3 signal
190 Pain Of Skin 9 2.3 2.3 signal
191 Haemorrhage Intracranial 5 2.3 2.3 no signal
192 Blood Thyroid Stimulating Hormone Increased 3 2.2 2.2 no signal
193 Ovarian Cancer 3 2.2 2.2 no signal
194 Injection Site Discolouration 4 2.2 2.2 no signal
195 Muscle Spasticity 4 2.2 2.2 no signal
196 Osteonecrosis Of Jaw 8 2.2 2.2 signal
197 Deformity 3 2.2 2.2 no signal
198 Tuberculosis 4 2.1 2.1 no signal
199 Thrombotic Microangiopathy 3 2.1 2.1 no signal
200 Parkinsonism 3 2.1 2.1 no signal
201 Malignant Neoplasm Progression 30 2.0 2.0 signal
202 Psoriasis 38 2.0 2.0 no signal
203 Femur Fracture 9 2.0 2.0 no signal
204 Skeletal Injury 3 1.9 1.9 no signal
205 Gastric Cancer 7 1.9 1.9 no signal
206 Application Site Pain 6 1.9 1.9 no signal
207 Product Availability Issue 6 1.8 1.8 no signal
208 Amenorrhoea 4 1.6 1.6 no signal
209 Myelosuppression 8 1.6 1.6 no signal
210 Genital Haemorrhage 3 1.6 1.6 no signal
211 Hair Texture Abnormal 3 1.5 1.5 no signal
212 Overdose 44 1.4 1.4 no signal
213 Dermatitis Atopic 10 1.4 1.4 no signal
214 Device Failure 3 1.3 1.3 no signal
215 Needle Issue 5 1.2 1.2 no signal
216 Drug Dependence 27 1.1 1.1 no signal
217 Foetal Exposure During Pregnancy 13 1.1 1.1 no signal
218 Application Site Erythema 4 1.0 1.0 no signal
219 Product Preparation Error 3 1.0 1.0 no signal
220 Injection Site Mass 5 0.9 0.9 no signal
221 Device Leakage 5 0.8 0.8 no signal
222 Device Dislocation 5 0.8 0.8 no signal