Drug

Sodium Zirconium Cyclosilicate

52 flagged reaction(s) · 2,509 total co-reports · max PRR 67.6

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Blood Potassium Increased	191	67.6	71.2	signal
2	Hyperkalaemia	150	24.5	25.5	signal
3	End Stage Renal Disease	55	17.0	17.2	signal
4	Glomerular Filtration Rate Decreased	23	10.8	10.9	signal
5	Hypokalaemia	71	8.8	8.9	signal
6	Blood Potassium Decreased	44	8.3	8.4	signal
7	Death	1,088	7.2	9.8	signal
8	Oedema	68	7.1	7.3	signal
9	Ileus	15	6.9	6.9	signal
10	Cardiac Failure	90	6.4	6.5	signal
11	Dialysis	14	5.6	5.6	signal
12	Nephropathy	9	5.4	5.5	signal
13	Chronic Kidney Disease	72	5.3	5.4	signal
14	Toxic Epidermal Necrolysis	14	5.3	5.3	signal
15	Renal Disorder	43	5.2	5.3	signal
16	Inability To Afford Medication	9	5.2	5.2	signal
17	Renal Impairment	69	4.7	4.8	signal
18	Blood Calcium Decreased	9	4.5	4.5	signal
19	Incorrect Route Of Product Administration	13	4.4	4.4	signal
20	Blood Creatinine Increased	47	4.1	4.1	signal
21	Stevens-johnson Syndrome	16	4.1	4.1	signal
22	Blood Urea Increased	12	4.0	4.1	signal
23	Intestinal Perforation	8	4.0	4.0	signal
24	Proteinuria	12	3.6	3.6	signal
25	Choking	12	3.5	3.5	signal
26	Product Taste Abnormal	8	3.4	3.4	signal
27	Renal Failure	79	3.4	3.4	signal
28	Blindness	23	3.2	3.2	signal
29	Cardiac Failure Congestive	45	3.2	3.2	signal
30	Erythema Multiforme	5	3.0	3.0	signal
31	Colon Cancer	8	3.0	3.0	signal
32	Therapy Change	5	2.9	2.9	signal
33	Multiple Organ Dysfunction Syndrome	14	2.8	2.9	signal
34	Mouth Ulceration	10	2.7	2.7	signal
35	Fluid Overload	7	2.7	2.7	signal
36	Metabolic Acidosis	15	2.7	2.7	signal
37	Dementia	13	2.6	2.7	signal
38	Pharyngitis Streptococcal	5	2.6	2.6	no signal
39	Hypertensive Crisis	5	2.5	2.5	no signal
40	Rash Papular	10	2.5	2.5	signal
41	Posterior Reversible Encephalopathy Syndrome	4	2.4	2.4	no signal
42	Cerebral Infarction	10	2.3	2.3	signal
43	Sickle Cell Anaemia With Crisis	6	2.2	2.2	no signal
44	Fracture	7	2.1	2.1	no signal
45	Cerebral Haemorrhage	13	2.1	2.1	signal
46	Blindness Unilateral	5	2.0	2.0	no signal
47	Myelodysplastic Syndrome	5	2.0	2.0	no signal
48	Therapy Interrupted	22	1.8	1.8	no signal
49	Diabetes Mellitus Inadequate Control	5	1.6	1.6	no signal
50	Neoplasm Malignant	17	1.4	1.4	no signal
51	Myelosuppression	4	0.7	0.7	no signal
52	Renal Cancer	5	0.6	0.6	no signal