Drug

Tapinarof

32 flagged reaction(s) · 1,522 total co-reports · max PRR 337.4

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Folliculitis	283	337.4	402.2	signal
2	Dermatitis Contact	127	135.4	146.0	signal
3	Application Site Pruritus	55	29.1	30.0	signal
4	Application Site Erythema	61	27.8	28.8	signal
5	Application Site Pain	51	27.8	28.6	signal
6	Pain Of Skin	43	19.1	19.6	signal
7	Application Site Rash	19	16.5	16.7	signal
8	Application Site Irritation	15	14.5	14.6	signal
9	Skin Burning Sensation	81	13.7	14.3	signal
10	Dermatitis	19	11.0	11.1	signal
11	Skin Fissures	14	8.9	8.9	signal
12	Squamous Cell Carcinoma	6	7.6	7.7	signal
13	Scab	7	7.4	7.4	signal
14	Skin Discolouration	27	7.0	7.1	signal
15	Psoriasis	75	6.9	7.1	signal
16	Skin Reaction	8	6.8	6.8	signal
17	Rash Erythematous	26	6.6	6.7	signal
18	Pruritus	207	6.6	7.3	signal
19	Erythema	111	6.5	6.8	signal
20	Dermatitis Atopic	27	6.5	6.6	signal
21	Erythema Multiforme	5	6.4	6.4	signal
22	Skin Exfoliation	44	6.3	6.5	signal
23	Rebound Effect	6	6.3	6.4	signal
24	Swelling Face	33	6.1	6.2	signal
25	Skin Irritation	23	6.0	6.1	signal
26	Acne	35	5.5	5.6	signal
27	Eczema	23	5.5	5.5	signal
28	Sleep Disorder Due To A General Medical Condition	7	5.2	5.2	signal
29	Drug Effect Less Than Expected	5	4.2	4.3	signal
30	Influenza Like Illness	28	4.1	4.1	signal
31	Dry Skin	44	4.0	4.1	signal
32	Therapeutic Response Shortened	7	2.6	2.6	signal