OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Tenofovir Alafenamide

109 flagged reaction(s) · 2,441 total co-reports · max PRR 13.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Intentional Dose Omission 69 13.1 13.3 signal
2 Hepatic Cancer 49 10.4 10.6 signal
3 Drug Resistance 46 9.3 9.4 signal
4 Hepatic Cirrhosis 28 7.7 7.8 signal
5 Dialysis 18 6.5 6.6 signal
6 Osteoporosis 52 6.5 6.6 signal
7 Product Dispensing Error 24 5.7 5.7 signal
8 Glomerular Filtration Rate Decreased 13 5.5 5.6 signal
9 Product Dose Omission 71 5.5 5.6 signal
10 Hepatic Encephalopathy 10 5.5 5.5 signal
11 Neoplasm Malignant 68 5.3 5.3 signal
12 Transaminases Increased 22 5.1 5.1 signal
13 Osteopenia 15 5.1 5.1 signal
14 Cytopenia 11 4.8 4.8 signal
15 Economic Problem 14 4.7 4.7 signal
16 Pneumocystis Jirovecii Pneumonia 9 4.7 4.7 signal
17 Anhedonia 23 4.5 4.5 signal
18 Ventricular Extrasystoles 9 4.5 4.5 signal
19 Hepatic Failure 26 4.4 4.5 signal
20 Liver Disorder 38 4.4 4.5 signal
21 Product Dose Omission In Error 23 4.4 4.4 signal
22 Alanine Aminotransferase Increased 52 4.4 4.4 signal
23 Nephropathy Toxic 9 4.2 4.2 signal
24 Liver Function Test Increased 17 4.1 4.1 signal
25 Treatment Noncompliance 43 4.1 4.1 signal
26 Renal Impairment 65 4.0 4.1 signal
27 Renal Disorder 36 4.0 4.0 signal
28 End Stage Renal Disease 14 3.9 3.9 signal
29 Hepatic Function Abnormal 28 3.9 3.9 signal
30 Adrenal Insufficiency 9 3.9 3.9 signal
31 Leukaemia 7 3.8 3.8 signal
32 Proteinuria 13 3.6 3.6 signal
33 Quality Of Life Decreased 9 3.5 3.5 signal
34 Foetal Exposure During Pregnancy 54 3.4 3.5 signal
35 Cerebral Infarction 16 3.4 3.4 signal
36 Maternal Exposure During Pregnancy 56 3.3 3.3 signal
37 Fracture 12 3.3 3.3 signal
38 Product Dose Omission Issue 178 3.2 3.3 signal
39 Tuberculosis 8 3.2 3.2 signal
40 Liver Injury 15 3.2 3.2 signal
41 Chronic Kidney Disease 47 3.2 3.2 signal
42 Splenomegaly 7 3.1 3.1 signal
43 Jaundice 16 3.1 3.1 signal
44 Subarachnoid Haemorrhage 6 3.0 3.0 signal
45 Hyperbilirubinaemia 6 3.0 3.0 signal
46 Lymphoma 9 3.0 3.0 signal
47 Dementia 16 3.0 3.0 signal
48 Drug Eruption 10 2.9 2.9 signal
49 Decreased Activity 6 2.9 2.9 signal
50 Drug Interaction 88 2.9 2.9 signal
51 Cardiovascular Disorder 14 2.8 2.8 signal
52 Agranulocytosis 10 2.8 2.8 signal
53 Pancytopenia 30 2.8 2.8 signal
54 Appendicitis 5 2.8 2.8 signal
55 Nephropathy 5 2.8 2.8 no signal
56 Autoimmune Disorder 5 2.7 2.7 no signal
57 Dysphagia 49 2.7 2.7 signal
58 Type 2 Diabetes Mellitus 17 2.6 2.6 signal
59 Product Storage Error 43 2.6 2.6 signal
60 Hepatitis C 6 2.5 2.5 signal
61 Drug Level Decreased 5 2.5 2.5 no signal
62 Chromaturia 11 2.5 2.5 signal
63 Febrile Neutropenia 32 2.5 2.5 signal
64 Multiple Fractures 8 2.5 2.5 signal
65 Mouth Ulceration 10 2.5 2.5 signal
66 Acute Myocardial Infarction 14 2.4 2.4 signal
67 Therapy Cessation 24 2.4 2.4 signal
68 Renal Injury 14 2.4 2.4 signal
69 Spinal Fracture 9 2.3 2.3 signal
70 Surgery 26 2.3 2.3 signal
71 Product Use Issue 83 2.3 2.3 signal
72 Lactic Acidosis 14 2.3 2.3 signal
73 Metastases To Lung 5 2.2 2.2 no signal
74 Abortion Induced 4 2.2 2.2 no signal
75 Therapy Change 4 2.1 2.1 no signal
76 Blood Triglycerides Increased 7 2.0 2.0 no signal
77 Rhabdomyolysis 16 2.0 2.0 no signal
78 Cytokine Release Syndrome 7 1.9 1.9 no signal
79 Therapy Interrupted 24 1.8 1.8 no signal
80 Bone Density Decreased 11 1.8 1.8 no signal
81 Neurotoxicity 6 1.8 1.8 no signal
82 Metastases To Liver 6 1.8 1.8 no signal
83 Caesarean Section 4 1.8 1.8 no signal
84 Colon Cancer 5 1.7 1.7 no signal
85 Haemorrhage Intracranial 5 1.7 1.7 no signal
86 Brain Neoplasm 3 1.7 1.7 no signal
87 Inability To Afford Medication 3 1.6 1.6 no signal
88 Cytomegalovirus Infection 5 1.6 1.6 no signal
89 Premature Baby 9 1.5 1.5 no signal
90 Death 251 1.5 1.5 no signal
91 Glycosylated Haemoglobin Increased 7 1.4 1.4 no signal
92 Circumstance Or Information Capable Of Leading To Medication Error 9 1.4 1.4 no signal
93 Acute Myeloid Leukaemia 4 1.3 1.3 no signal
94 Product Physical Issue 5 1.3 1.3 no signal
95 Tooth Loss 5 1.2 1.2 no signal
96 Emotional Distress 29 1.2 1.2 no signal
97 Myelosuppression 8 1.2 1.2 no signal
98 Gastric Cancer 6 1.2 1.2 no signal
99 Oesophageal Carcinoma 7 1.2 1.2 no signal
100 Pancreatic Carcinoma 6 1.1 1.1 no signal
101 Bone Loss 3 1.0 1.0 no signal
102 Lung Neoplasm Malignant 8 1.0 1.0 no signal
103 Premature Delivery 3 1.0 1.0 no signal
104 Plasma Cell Myeloma 7 0.9 0.9 no signal
105 Extra Dose Administered 7 0.9 0.9 no signal
106 Abortion Spontaneous 6 0.8 0.8 no signal
107 Breast Cancer 13 0.7 0.7 no signal
108 Product Complaint 3 0.6 0.6 no signal
109 Prostate Cancer 6 0.4 0.4 no signal