Drug

Tramadol Hydrochloride And Acetaminophen

48 flagged reaction(s) · 629 total co-reports · max PRR 42.5

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Hand Deformity	24	42.5	43.6	signal
2	Helicobacter Infection	15	34.1	34.6	signal
3	Pemphigus	18	33.5	34.2	signal
4	Folliculitis	14	31.4	31.8	signal
5	Joint Range Of Motion Decreased	17	29.4	30.0	signal
6	Bursitis	14	26.9	27.3	signal
7	Synovitis	20	25.6	26.2	signal
8	Glossodynia	22	22.8	23.3	signal
9	Hypercholesterolaemia	9	21.8	22.0	signal
10	Back Injury	9	19.2	19.4	signal
11	Wound Infection	9	19.2	19.3	signal
12	Wound	21	17.5	17.9	signal
13	Obesity	12	17.4	17.6	signal
14	Back Disorder	12	17.0	17.2	signal
15	Pericarditis	12	16.7	16.9	signal
16	Irritable Bowel Syndrome	15	16.2	16.5	signal
17	Gait Inability	22	15.4	15.7	signal
18	Pulmonary Fibrosis	12	14.5	14.7	signal
19	Systemic Lupus Erythematosus	22	14.4	14.7	signal
20	Coeliac Disease	6	14.1	14.2	signal
21	Pneumocystis Jirovecii Pneumonia	6	13.9	14.0	signal
22	Fibromyalgia	14	13.3	13.5	signal
23	Lower Limb Fracture	10	12.1	12.2	signal
24	Altered State Of Consciousness	11	11.8	11.9	signal
25	Respiratory Depression	6	11.3	11.4	signal
26	Road Traffic Accident	20	11.1	11.3	signal
27	Type 2 Diabetes Mellitus	16	11.0	11.1	signal
28	Hepatitis	12	10.8	11.0	signal
29	Prescribed Overdose	9	10.8	10.9	signal
30	Lower Respiratory Tract Infection	21	10.7	10.9	signal
31	Hip Arthroplasty	7	10.7	10.7	signal
32	Prescribed Underdose	9	10.4	10.5	signal
33	Arthropathy	25	10.4	10.6	signal
34	Epilepsy	13	9.9	10.0	signal
35	Muscle Rigidity	5	9.7	9.7	signal
36	Interstitial Lung Disease	18	8.6	8.8	signal
37	Serotonin Syndrome	7	8.5	8.5	signal
38	Psoriatic Arthropathy	13	7.5	7.6	signal
39	Poisoning Deliberate	3	7.5	7.5	signal
40	Poisoning	4	7.3	7.4	signal
41	Sedation	8	7.1	7.2	signal
42	Intentional Overdose	19	6.9	7.0	signal
43	Rheumatoid Arthritis	28	5.7	5.9	signal
44	Ankylosing Spondylitis	3	5.3	5.3	signal
45	Completed Suicide	17	4.7	4.7	signal
46	Suicide Attempt	12	4.6	4.6	signal
47	Intentional Drug Misuse	4	4.4	4.4	signal
48	Extrapyramidal Disorder	4	3.7	3.7	signal