Drug

Trimipramine

94 flagged reaction(s) · 1,712 total co-reports · max PRR 56.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Gastrointestinal Pain	32	56.8	58.5	signal
2	Brain Oedema	36	55.5	57.3	signal
3	Pharyngitis	33	51.5	53.1	signal
4	Musculoskeletal Disorder	33	33.5	34.5	signal
5	Feeding Disorder	34	33.1	34.2	signal
6	Pneumonia Aspiration	41	32.0	33.2	signal
7	Helicobacter Infection	16	30.5	30.9	signal
8	Eating Disorder	33	30.0	30.9	signal
9	Apathy	21	28.1	28.6	signal
10	Hypophagia	34	26.0	26.8	signal
11	Vitamin D Deficiency	13	25.9	26.2	signal
12	Ear Infection	35	25.6	26.4	signal
13	Coma	62	25.3	26.7	signal
14	Breast Cancer Metastatic	13	23.5	23.8	signal
15	Aspiration	13	23.3	23.6	signal
16	Folliculitis	11	20.7	20.9	signal
17	Supraventricular Tachycardia	10	20.3	20.5	signal
18	Obesity	16	19.5	19.7	signal
19	Hypertensive Crisis	11	19.1	19.3	signal
20	Adverse Reaction	13	19.0	19.2	signal
21	Arthropathy	48	16.7	17.4	signal
22	Hand Deformity	11	16.3	16.5	signal
23	Electrocardiogram Qt Prolonged	30	16.2	16.6	signal
24	Bursitis	10	16.1	16.2	signal
25	Oral Herpes	16	16.0	16.2	signal
26	Middle Insomnia	15	15.7	15.9	signal
27	Pemphigus	10	15.6	15.7	signal
28	Poisoning	10	15.4	15.5	signal
29	Pulmonary Oedema	34	14.7	15.2	signal
30	Blood Thyroid Stimulating Hormone Increased	7	14.7	14.8	signal
31	Metastases To Bone	12	14.2	14.4	signal
32	Toxicity To Various Agents	123	14.2	15.9	signal
33	Deafness	19	14.1	14.3	signal
34	Incorrect Route Of Product Administration	12	13.9	14.0	signal
35	Irritable Bowel Syndrome	15	13.6	13.8	signal
36	Myocardial Ischaemia	8	13.5	13.6	signal
37	Haematoma	18	13.4	13.6	signal
38	Pericarditis	11	12.8	12.9	signal
39	Depressed Level Of Consciousness	26	12.8	13.1	signal
40	Wound	18	12.6	12.8	signal
41	Drug Abuse	53	12.3	12.9	signal
42	Posterior Reversible Encephalopathy Syndrome	6	12.2	12.3	signal
43	Restlessness	23	12.2	12.4	signal
44	Metastases To Liver	11	12.2	12.3	signal
45	Autoimmune Disorder	6	12.2	12.2	signal
46	Drug Interaction	97	11.9	12.9	signal
47	Joint Range Of Motion Decreased	8	11.6	11.7	signal
48	Blood Iron Decreased	7	11.5	11.6	signal
49	Motor Dysfunction	6	11.5	11.6	signal
50	Polyneuropathy	7	11.4	11.5	signal
51	Petechiae	6	11.2	11.3	signal
52	Completed Suicide	47	10.8	11.3	signal
53	Synovitis	10	10.8	10.8	signal
54	Impaired Healing	18	10.6	10.8	signal
55	Intervertebral Disc Protrusion	12	10.6	10.7	signal
56	Obstructive Airways Disorder	6	10.4	10.5	signal
57	Scar	9	10.2	10.3	signal
58	Internal Haemorrhage	6	10.2	10.2	signal
59	Gastrointestinal Disorder	45	9.9	10.3	signal
60	Central Nervous System Lesion	7	9.8	9.9	signal
61	Suicide Attempt	30	9.6	9.8	signal
62	Glossodynia	11	9.5	9.6	signal
63	Aggression	24	9.3	9.5	signal
64	Full Blood Count Abnormal	5	9.2	9.2	signal
65	Fibromyalgia	11	8.8	8.9	signal
66	Sopor	6	8.7	8.8	signal
67	Disturbance In Attention	24	8.6	8.8	signal
68	Affect Lability	4	8.0	8.1	signal
69	Sluggishness	4	7.6	7.7	signal
70	Adverse Drug Reaction	34	7.4	7.6	signal
71	Nightmare	13	7.3	7.3	signal
72	Generalised Tonic-clonic Seizure	6	7.1	7.1	signal
73	Underdose	26	6.9	7.0	signal
74	Abdominal Pain Lower	9	6.9	6.9	signal
75	Metastases To Lung	4	6.7	6.7	signal
76	Paranoia	6	6.7	6.8	signal
77	Sedation	9	6.7	6.7	signal
78	Mood Swings	11	6.7	6.7	signal
79	Product Prescribing Issue	7	6.7	6.7	signal
80	Sexual Dysfunction	4	6.6	6.7	signal
81	Product Prescribing Error	8	6.6	6.6	signal
82	Agranulocytosis	6	6.3	6.3	signal
83	Systemic Lupus Erythematosus	11	6.0	6.1	signal
84	Abnormal Behaviour	11	5.4	5.4	signal
85	Erectile Dysfunction	7	5.3	5.3	signal
86	Intentional Overdose	17	5.2	5.2	signal
87	Dystonia	5	5.0	5.0	signal
88	Drug Prescribing Error	5	5.0	5.0	signal
89	Bone Density Decreased	8	4.9	4.9	signal
90	Schizophrenia	3	4.8	4.8	signal
91	Foetal Exposure During Pregnancy	19	4.5	4.6	signal
92	Extrapyramidal Disorder	5	3.9	3.9	signal
93	Intentional Self-injury	3	2.9	2.9	no signal
94	Dependence	3	1.0	1.0	no signal