Drug

Velaglucerase Alfa

88 flagged reaction(s) · 2,183 total co-reports · max PRR 65.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Poor Venous Access	66	65.8	68.0	signal
2	Weight Fluctuation	37	36.5	37.1	signal
3	Insurance Issue	49	33.9	34.7	signal
4	Product Availability Issue	64	29.3	30.2	signal
5	Pregnancy	46	23.3	23.8	signal
6	Splenomegaly	19	16.6	16.8	signal
7	Infusion Related Reaction	102	15.8	16.6	signal
8	Bone Pain	89	15.6	16.2	signal
9	Infusion Site Pain	16	12.8	12.9	signal
10	Inappropriate Schedule Of Product Administration	212	12.3	13.6	signal
11	Inability To Afford Medication	11	11.5	11.5	signal
12	Blood Pressure Abnormal	21	10.9	11.0	signal
13	Body Height Decreased	11	10.4	10.5	signal
14	Hepatomegaly	10	10.4	10.4	signal
15	Product Prescribing Error	23	9.9	10.1	signal
16	Covid-19	167	9.7	10.4	signal
17	Wrist Fracture	11	9.4	9.4	signal
18	Upper Limb Fracture	18	9.2	9.3	signal
19	Abortion Spontaneous	36	9.2	9.3	signal
20	Osteonecrosis	29	9.0	9.1	signal
21	Exposure During Pregnancy	54	8.9	9.1	signal
22	Appendicitis	8	8.8	8.8	signal
23	Flank Pain	8	8.8	8.8	signal
24	Pharyngitis Streptococcal	9	8.5	8.5	signal
25	Body Temperature Increased	16	8.0	8.1	signal
26	Rib Fracture	16	8.0	8.0	signal
27	Femur Fracture	24	7.9	8.0	signal
28	Retinal Detachment	7	7.8	7.8	signal
29	Sciatica	12	7.7	7.8	signal
30	Myoclonus	9	7.7	7.8	signal
31	Skin Infection	8	7.3	7.4	signal
32	Ligament Sprain	7	7.3	7.3	signal
33	Blood Pressure Fluctuation	17	7.2	7.3	signal
34	Product Dose Omission Issue	198	7.1	7.8	signal
35	Lower Limb Fracture	13	7.0	7.0	signal
36	Treatment Noncompliance	36	6.8	6.9	signal
37	Skin Laceration	7	6.6	6.7	signal
38	Ankle Fracture	10	6.6	6.6	signal
39	Seasonal Allergy	9	6.5	6.6	signal
40	Cholelithiasis	20	6.2	6.3	signal
41	Body Temperature Decreased	6	6.2	6.2	signal
42	Spinal Pain	7	6.1	6.1	signal
43	Blood Iron Decreased	7	6.1	6.1	signal
44	Joint Dislocation	6	5.8	5.8	signal
45	Epilepsy	17	5.7	5.7	signal
46	Gout	10	5.7	5.7	signal
47	Bone Disorder	10	5.6	5.6	signal
48	Rotator Cuff Syndrome	7	5.6	5.6	signal
49	Increased Tendency To Bruise	5	5.6	5.6	signal
50	Psychomotor Hyperactivity	9	5.5	5.5	signal
51	Hepatic Cirrhosis	10	5.5	5.5	signal
52	Personality Change	5	5.5	5.5	signal
53	Road Traffic Accident	22	5.4	5.4	signal
54	Post Procedural Haemorrhage	6	5.3	5.3	signal
55	Basal Cell Carcinoma	8	5.2	5.3	signal
56	Influenza	56	5.1	5.2	signal
57	Ovarian Cyst	5	5.1	5.1	signal
58	Localised Infection	12	5.1	5.1	signal
59	Muscle Tightness	8	5.1	5.1	signal
60	Limb Injury	13	4.9	4.9	signal
61	Weight Increased	106	4.9	5.1	signal
62	Heart Rate Decreased	16	4.6	4.7	signal
63	Sars-cov-2 Test Positive	6	4.6	4.6	signal
64	Inappropriate Schedule Of Drug Administration	31	4.4	4.4	signal
65	Illness	41	4.2	4.2	signal
66	Coeliac Disease	4	4.2	4.2	signal
67	Mood Altered	11	4.1	4.2	signal
68	Plasma Cell Myeloma	15	3.9	3.9	signal
69	Malignant Melanoma	5	3.8	3.8	signal
70	Status Epilepticus	4	3.6	3.6	signal
71	Product Prescribing Issue	7	3.5	3.5	signal
72	No Adverse Event	58	3.3	3.4	signal
73	Brain Neoplasm	3	3.3	3.3	no signal
74	Abortion Induced	3	3.3	3.3	no signal
75	Eye Inflammation	3	3.3	3.3	no signal
76	Complication Associated With Device	4	3.1	3.1	no signal
77	Product Preparation Error	6	3.0	3.0	signal
78	Central Nervous System Lesion	4	3.0	3.0	no signal
79	Hepatic Cancer	7	3.0	3.0	signal
80	Incorrect Product Administration Duration	5	2.5	2.5	no signal
81	Dysmenorrhoea	3	2.3	2.3	no signal
82	Product Storage Error	17	2.0	2.0	signal
83	Gastric Cancer	5	2.0	2.0	no signal
84	Incorrect Dose Administered	43	2.0	2.0	no signal
85	Pancreatic Carcinoma	5	1.8	1.8	no signal
86	Menstruation Irregular	4	1.5	1.5	no signal
87	Oesophageal Carcinoma	4	1.4	1.4	no signal
88	Device Issue	9	1.1	1.1	no signal