OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Verapamil Hydrochloride

249 flagged reaction(s) · 12,425 total co-reports · max PRR 68.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Ocular Discomfort 148 68.3 70.7 signal
2 Generalised Oedema 129 52.3 53.9 signal
3 Head Discomfort 155 43.9 45.5 signal
4 Cardiogenic Shock 111 38.8 39.8 signal
5 Altered State Of Consciousness 167 38.6 40.1 signal
6 Photophobia 125 33.3 34.3 signal
7 Haematemesis 158 30.9 32.1 signal
8 Ascites 161 27.2 28.2 signal
9 Presyncope 132 27.1 28.0 signal
10 Cardio-respiratory Arrest 196 23.1 24.2 signal
11 Diplopia 119 22.8 23.4 signal
12 Coma 202 21.0 22.0 signal
13 Haematuria 143 20.7 21.4 signal
14 Bradycardia 213 19.9 20.9 signal
15 Blindness 153 18.6 19.3 signal
16 Shock 75 16.3 16.6 signal
17 Completed Suicide 236 13.9 14.7 signal
18 Tinnitus 129 13.9 14.3 signal
19 Eye Pain 149 13.4 13.8 signal
20 Acute Respiratory Distress Syndrome 46 12.9 13.0 signal
21 Sinus Bradycardia 25 12.8 12.9 signal
22 Tachycardia 228 12.7 13.4 signal
23 Supraventricular Tachycardia 22 11.4 11.5 signal
24 Ventricular Extrasystoles 23 11.0 11.0 signal
25 Ischaemic Stroke 39 10.8 10.9 signal
26 Drug Interaction 315 9.8 10.5 signal
27 Ileus 24 9.7 9.7 signal
28 Metabolic Acidosis 60 9.4 9.5 signal
29 Hyperkalaemia 62 8.8 8.9 signal
30 Atelectasis 17 8.7 8.7 signal
31 Sepsis 188 8.3 8.7 signal
32 Toxic Skin Eruption 17 8.3 8.4 signal
33 Extrapyramidal Disorder 42 8.3 8.4 signal
34 Quality Of Life Decreased 22 8.1 8.1 signal
35 Cerebral Infarction 40 8.1 8.2 signal
36 Intentional Overdose 103 8.0 8.2 signal
37 Mitral Valve Incompetence 18 7.9 7.9 signal
38 Hypomagnesaemia 22 7.9 7.9 signal
39 Oesophagitis 17 7.7 7.7 signal
40 Syncope 155 7.7 7.9 signal
41 Electrocardiogram Qt Prolonged 55 7.6 7.7 signal
42 Lactic Acidosis 49 7.6 7.6 signal
43 Drug Toxicity 21 7.5 7.6 signal
44 Hypotension 287 7.1 7.5 signal
45 Breast Pain 15 7.0 7.0 signal
46 Respiratory Distress 38 6.8 6.9 signal
47 Pulmonary Congestion 18 6.7 6.8 signal
48 Hypercholesterolaemia 13 6.7 6.7 signal
49 Nerve Injury 15 6.7 6.7 signal
50 Nocturia 16 6.5 6.6 signal
51 Blood Pressure Increased 202 6.5 6.8 signal
52 Body Temperature Decreased 13 6.5 6.5 signal
53 Atrial Fibrillation 126 6.4 6.6 signal
54 Poisoning Deliberate 12 6.4 6.4 signal
55 Circulatory Collapse 22 6.4 6.4 signal
56 Chills 151 6.4 6.6 signal
57 Drug Ineffective For Unapproved Indication 71 6.3 6.4 signal
58 Eosinophilia 22 6.2 6.3 signal
59 Ventricular Fibrillation 14 6.2 6.2 signal
60 Myocarditis 14 6.1 6.1 signal
61 Cyanosis 19 6.0 6.0 signal
62 Multiple Organ Dysfunction Syndrome 33 5.9 5.9 signal
63 Toxicity To Various Agents 196 5.8 6.0 signal
64 Rotator Cuff Syndrome 15 5.8 5.8 signal
65 Angina Pectoris 33 5.7 5.7 signal
66 Joint Dislocation 12 5.6 5.7 signal
67 Disseminated Intravascular Coagulation 16 5.6 5.6 signal
68 Cardiomegaly 14 5.6 5.6 signal
69 Toxic Epidermal Necrolysis 17 5.6 5.6 signal
70 Sudden Death 12 5.6 5.6 signal
71 Aspiration 12 5.5 5.5 signal
72 Heart Rate Decreased 39 5.5 5.5 signal
73 Respiratory Failure 80 5.4 5.5 signal
74 Motor Dysfunction 11 5.4 5.4 signal
75 Bursitis 13 5.3 5.3 signal
76 Nephropathy 10 5.3 5.3 signal
77 Rhabdomyolysis 44 5.2 5.3 signal
78 Myocardial Ischaemia 12 5.2 5.2 signal
79 Electrolyte Imbalance 12 5.2 5.2 signal
80 Abdominal Pain 242 5.2 5.4 signal
81 Arrhythmia 49 5.1 5.1 signal
82 Drug Level Increased 17 5.1 5.1 signal
83 Drug Eruption 18 5.1 5.1 signal
84 Cardiac Arrest 84 5.0 5.1 signal
85 Myoclonus 12 5.0 5.0 signal
86 Haematoma 26 4.9 5.0 signal
87 Vision Blurred 136 4.9 5.1 signal
88 Hyperglycaemia 36 4.9 4.9 signal
89 Somnolence 187 4.6 4.8 signal
90 Contraindicated Product Administered 28 4.6 4.6 signal
91 Blood Pressure Decreased 61 4.6 4.6 signal
92 Hepatocellular Injury 13 4.5 4.5 signal
93 Hypoxia 32 4.5 4.5 signal
94 Dyspnoea Exertional 34 4.5 4.5 signal
95 Emphysema 9 4.4 4.4 signal
96 Myalgia 150 4.4 4.5 signal
97 Heart Rate Irregular 20 4.4 4.4 signal
98 Poisoning 11 4.3 4.3 signal
99 Iron Deficiency Anaemia 8 4.3 4.3 signal
100 Cough 241 4.3 4.5 signal
101 Melaena 19 4.3 4.3 signal
102 Flank Pain 8 4.2 4.2 signal
103 Interstitial Lung Disease 41 4.2 4.2 signal
104 Cardiac Failure 68 4.2 4.2 signal
105 Gout 15 4.1 4.1 signal
106 Hyperthyroidism 12 4.1 4.1 signal
107 Thrombotic Microangiopathy 8 4.1 4.1 signal
108 Restless Legs Syndrome 15 4.1 4.1 signal
109 Pneumonia Aspiration 20 4.0 4.0 signal
110 Hypotonia 8 3.9 4.0 signal
111 Brain Injury 8 3.9 3.9 signal
112 Mental Status Changes 22 3.9 3.9 signal
113 Blood Creatine Phosphokinase Increased 23 3.9 3.9 signal
114 Abdominal Pain Upper 161 3.9 4.0 signal
115 White Blood Cell Count Increased 30 3.9 3.9 signal
116 Intervertebral Disc Protrusion 17 3.8 3.8 signal
117 Rash Maculo-papular 17 3.8 3.8 signal
118 Hypokalaemia 35 3.8 3.8 signal
119 Blood Thyroid Stimulating Hormone Increased 7 3.7 3.8 signal
120 Renal Impairment 63 3.7 3.8 signal
121 Acute Kidney Injury 114 3.7 3.8 signal
122 Orthostatic Hypotension 13 3.7 3.7 signal
123 Cardiovascular Disorder 19 3.7 3.7 signal
124 Multi-organ Failure 13 3.7 3.7 signal
125 Suicide Attempt 45 3.7 3.7 signal
126 Hepatic Cytolysis 9 3.6 3.6 signal
127 Pulmonary Oedema 33 3.6 3.7 signal
128 Encephalopathy 18 3.6 3.6 signal
129 Decreased Appetite 169 3.6 3.7 signal
130 Hernia 14 3.6 3.6 signal
131 Ventricular Tachycardia 12 3.6 3.6 signal
132 Stevens-johnson Syndrome 16 3.6 3.6 signal
133 C-reactive Protein Increased 26 3.5 3.6 signal
134 Pleural Effusion 43 3.5 3.5 signal
135 Fall 234 3.5 3.6 signal
136 Insomnia 182 3.4 3.5 signal
137 Sleep Apnoea Syndrome 13 3.4 3.4 signal
138 Hyponatraemia 38 3.3 3.4 signal
139 Acute Myocardial Infarction 20 3.3 3.4 signal
140 International Normalised Ratio Increased 19 3.3 3.3 signal
141 Depressed Level Of Consciousness 26 3.3 3.3 signal
142 Migraine 62 3.2 3.3 signal
143 Blood Urea Increased 11 3.2 3.2 signal
144 Wound 18 3.2 3.2 signal
145 Middle Insomnia 12 3.2 3.2 signal
146 Cerebral Haemorrhage 23 3.2 3.2 signal
147 Eye Inflammation 6 3.1 3.1 signal
148 Pneumothorax 10 3.1 3.1 signal
149 Cholestasis 12 3.1 3.1 signal
150 Ulcer 10 3.1 3.1 signal
151 Blood Lactate Dehydrogenase Increased 10 3.1 3.1 signal
152 Hypertensive Crisis 7 3.1 3.1 signal
153 Drug Reaction With Eosinophilia And Systemic Symptoms 16 3.1 3.1 signal
154 Dyspnoea 353 3.1 3.3 signal
155 Overdose 135 3.1 3.2 signal
156 Coronary Artery Disease 19 3.1 3.1 signal
157 Blood Calcium Decreased 7 3.1 3.1 signal
158 Neuralgia 15 3.1 3.1 signal
159 Pulmonary Arterial Hypertension 9 3.1 3.1 signal
160 Dyspepsia 60 3.0 3.1 signal
161 Asthenia 229 3.0 3.1 signal
162 Leukocytosis 11 3.0 3.0 signal
163 Palpitations 71 3.0 3.0 signal
164 Renal Failure 81 3.0 3.0 signal
165 Renal Failure Acute 26 3.0 3.0 signal
166 Agranulocytosis 11 2.9 2.9 signal
167 Pruritus 224 2.9 3.0 signal
168 Inappropriate Antidiuretic Hormone Secretion 6 2.9 2.9 signal
169 Osteoarthritis 25 2.9 2.9 signal
170 Intestinal Obstruction 22 2.9 2.9 signal
171 Disease Recurrence 28 2.9 2.9 signal
172 Anaphylactic Shock 15 2.9 2.9 signal
173 Blood Pressure Fluctuation 14 2.9 2.9 signal
174 Liver Function Test Abnormal 17 2.9 2.9 signal
175 Dizziness 289 2.9 3.0 signal
176 Peripheral Coldness 8 2.9 2.9 signal
177 Renal Pain 6 2.8 2.8 signal
178 Respiratory Disorder 17 2.8 2.8 signal
179 Hepatic Function Abnormal 21 2.8 2.8 signal
180 Hypothyroidism 18 2.8 2.8 signal
181 Anaphylactic Reaction 31 2.8 2.8 signal
182 Treatment Failure 46 2.8 2.8 signal
183 Blood Potassium Increased 9 2.7 2.7 signal
184 Erectile Dysfunction 14 2.7 2.7 signal
185 Coagulopathy 9 2.7 2.7 signal
186 Colon Cancer 8 2.6 2.7 signal
187 Deafness 14 2.6 2.6 signal
188 Tubulointerstitial Nephritis 10 2.6 2.6 signal
189 Pulmonary Hypertension 11 2.6 2.6 signal
190 Vertigo 31 2.5 2.5 signal
191 Malaise 223 2.5 2.6 signal
192 Ligament Sprain 5 2.5 2.5 no signal
193 Unresponsive To Stimuli 13 2.5 2.5 signal
194 Blood Pressure Abnormal 10 2.5 2.5 signal
195 Haemoptysis 14 2.5 2.5 signal
196 Arthralgia 207 2.5 2.5 signal
197 Subarachnoid Haemorrhage 5 2.4 2.4 no signal
198 Pericarditis 8 2.4 2.4 signal
199 Epistaxis 34 2.2 2.3 signal
200 Hypoglycaemia 22 2.2 2.2 signal
201 Gamma-glutamyltransferase Increased 10 2.2 2.2 signal
202 Chronic Obstructive Pulmonary Disease 23 2.2 2.2 signal
203 Gingival Bleeding 6 2.2 2.2 no signal
204 Mental Disorder 19 2.2 2.2 signal
205 Gastric Haemorrhage 5 2.1 2.1 no signal
206 Hepatic Failure 13 2.1 2.1 signal
207 Lymphopenia 6 2.1 2.1 no signal
208 Disturbance In Attention 23 2.1 2.1 signal
209 Product Prescribing Error 10 2.1 2.1 signal
210 Bronchospasm 6 2.1 2.1 no signal
211 Swollen Tongue 13 2.1 2.1 signal
212 Nervous System Disorder 13 2.1 2.1 signal
213 Face Oedema 7 2.0 2.0 no signal
214 Panic Attack 15 2.0 2.0 signal
215 Respiratory Depression 5 2.0 2.0 no signal
216 No Therapeutic Response 5 2.0 2.0 no signal
217 Pneumocystis Jirovecii Pneumonia 4 2.0 2.0 no signal
218 Medication Error 22 2.0 2.0 no signal
219 Lip Swelling 13 1.9 1.9 no signal
220 Mydriasis 5 1.9 1.9 no signal
221 Accidental Overdose 14 1.9 1.9 no signal
222 Cerebrovascular Accident 65 1.9 1.9 no signal
223 Cardiac Failure Congestive 31 1.9 1.9 no signal
224 Respiratory Arrest 10 1.8 1.8 no signal
225 Angioedema 15 1.7 1.7 no signal
226 Premature Baby 10 1.6 1.6 no signal
227 Mood Altered 9 1.6 1.6 no signal
228 Leukaemia 3 1.6 1.6 no signal
229 Product Substitution Issue 18 1.5 1.5 no signal
230 Anorexia 4 1.5 1.5 no signal
231 Hair Texture Abnormal 4 1.5 1.5 no signal
232 Drug Level Decreased 3 1.5 1.5 no signal
233 Coronary Artery Occlusion 4 1.4 1.4 no signal
234 Prostatic Specific Antigen Increased 4 1.4 1.4 no signal
235 Drug Abuse 22 1.3 1.3 no signal
236 Convulsion 15 1.3 1.3 no signal
237 Neuroleptic Malignant Syndrome 3 1.2 1.2 no signal
238 Multiple Sclerosis 12 1.2 1.2 no signal
239 Injection Site Irritation 3 1.2 1.2 no signal
240 Injection Site Induration 3 1.1 1.1 no signal
241 Sopor 3 1.1 1.1 no signal
242 Gastric Cancer 5 1.0 1.0 no signal
243 Drug Dispensing Error 3 1.0 1.0 no signal
244 Incorrect Route Of Drug Administration 6 0.8 0.8 no signal
245 Dermatitis Atopic 6 0.6 0.6 no signal
246 Pharmaceutical Product Complaint 3 0.6 0.6 no signal
247 Breast Cancer Female 3 0.6 0.6 no signal
248 Drug Withdrawal Syndrome 9 0.5 0.5 no signal
249 Prostate Cancer 7 0.4 0.4 no signal