Drug

Vorinostat

63 flagged reaction(s) · 2,244 total co-reports · max PRR 35.4

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Febrile Neutropenia	239	35.4	39.7	signal
2	Lymphopenia	42	29.3	29.8	signal
3	Acute Myeloid Leukaemia	40	25.2	25.6	signal
4	Electrocardiogram Qt Prolonged	68	18.5	19.1	signal
5	Haematotoxicity	17	17.9	18.1	signal
6	Lung Infection	28	17.4	17.6	signal
7	Mucosal Inflammation	39	14.6	14.9	signal
8	Device Related Infection	22	13.9	14.1	signal
9	Myelodysplastic Syndrome	20	13.5	13.6	signal
10	Hyperbilirubinaemia	14	13.3	13.4	signal
11	Thrombocytopenia	151	13.2	14.2	signal
12	Hypocalcaemia	25	13.0	13.1	signal
13	Neutrophil Count Decreased	52	12.6	12.8	signal
14	Hypokalaemia	52	11.1	11.3	signal
15	Bacteraemia	13	10.8	10.9	signal
16	Haemorrhage Intracranial	16	10.4	10.5	signal
17	Sinus Bradycardia	10	10.1	10.1	signal
18	Platelet Count Decreased	106	9.7	10.2	signal
19	Sepsis	111	9.7	10.2	signal
20	Small Intestinal Obstruction	12	9.6	9.6	signal
21	Bone Marrow Failure	20	9.6	9.6	signal
22	Hyperglycaemia	35	9.4	9.6	signal
23	Pneumonitis	26	9.4	9.5	signal
24	Lymphocyte Count Decreased	17	9.4	9.5	signal
25	Hypercalcaemia	11	8.7	8.8	signal
26	Hypoxia	31	8.6	8.8	signal
27	Candida Infection	14	8.2	8.3	signal
28	Electrolyte Imbalance	9	7.6	7.7	signal
29	Dehydration	102	7.5	7.8	signal
30	Hyponatraemia	42	7.3	7.4	signal
31	Colitis	28	7.3	7.4	signal
32	Choking	14	7.0	7.1	signal
33	Respiratory Failure	52	7.0	7.1	signal
34	Anaemia	135	6.9	7.3	signal
35	Sinus Tachycardia	10	6.9	6.9	signal
36	Gastric Haemorrhage	8	6.8	6.8	signal
37	Anorexia	9	6.7	6.8	signal
38	Neutropenia	93	6.7	7.0	signal
39	Brain Neoplasm	6	6.4	6.4	signal
40	Metastases To Lung	7	5.9	5.9	signal
41	Respiratory Arrest	16	5.6	5.7	signal
42	Sudden Death	6	5.5	5.5	signal
43	Renal Failure Acute	24	5.5	5.5	signal
44	Appendicitis	5	5.3	5.3	signal
45	Product Use In Unapproved Indication	130	5.2	5.5	signal
46	Posterior Reversible Encephalopathy Syndrome	5	5.1	5.1	signal
47	Pericardial Effusion	12	5.1	5.1	signal
48	Malignant Neoplasm Progression	53	5.1	5.2	signal
49	Disease Progression	61	5.1	5.2	signal
50	Multi-organ Failure	9	5.0	5.0	signal
51	Plasma Cell Myeloma	18	4.5	4.5	signal
52	Pancytopenia	25	4.4	4.4	signal
53	Intestinal Perforation	5	4.3	4.4	signal
54	Epistaxis	33	4.3	4.4	signal
55	White Blood Cell Count Decreased	46	4.1	4.2	signal
56	Cytopenia	5	4.1	4.1	signal
57	Hepatitis C	5	4.0	4.0	signal
58	Metastases To Central Nervous System	5	3.8	3.8	signal
59	Nephropathy Toxic	4	3.5	3.5	signal
60	Convulsion	17	2.9	2.9	signal
61	Palmar-plantar Erythrodysaesthesia Syndrome	5	2.1	2.1	no signal
62	Intentional Drug Misuse	4	1.8	1.8	no signal
63	Myelosuppression	5	1.4	1.4	no signal