OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Ziprasidone Hcl

130 flagged reaction(s) · 8,251 total co-reports · max PRR 268.6
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Sexual Dysfunction 384 268.6 313.9 signal
2 Personality Change 296 258.2 290.5 signal
3 Dystonia 388 160.7 188.0 signal
4 Sedation 405 124.6 146.9 signal
5 Schizophrenia 187 123.3 132.6 signal
6 Akathisia 180 105.5 113.1 signal
7 Euphoric Mood 115 89.1 93.1 signal
8 Dyskinesia 393 77.3 90.5 signal
9 Parkinsonism 82 67.0 69.1 signal
10 Leukaemia 76 64.2 66.0 signal
11 Obesity 128 63.9 67.0 signal
12 Suicide Attempt 474 62.1 75.4 signal
13 Increased Appetite 118 49.9 52.2 signal
14 Insurance Issue 80 42.8 44.1 signal
15 Neuroleptic Malignant Syndrome 60 40.0 40.9 signal
16 Prescribed Overdose 71 29.1 29.8 signal
17 Completed Suicide 231 21.7 23.7 signal
18 Hallucination, Auditory 41 20.4 20.7 signal
19 Delusion 32 16.4 16.5 signal
20 Psychotic Disorder 61 16.3 16.7 signal
21 Extrapyramidal Disorder 51 16.1 16.4 signal
22 Leukopenia 101 16.0 16.6 signal
23 Respiratory Arrest 56 15.9 16.3 signal
24 Mania 32 15.4 15.6 signal
25 Diabetes Mellitus 147 15.2 16.0 signal
26 Paranoia 33 15.1 15.3 signal
27 Electrocardiogram Qt Prolonged 66 14.5 14.9 signal
28 Blood Triglycerides Increased 31 13.8 14.0 signal
29 Blood Glucose Increased 329 13.8 15.6 signal
30 Bipolar Disorder 18 13.0 13.1 signal
31 Drug Toxicity 22 12.6 12.7 signal
32 Therapeutic Product Effect Incomplete 111 12.4 12.9 signal
33 Adverse Drug Reaction 128 11.3 11.8 signal
34 Serotonin Syndrome 27 11.2 11.3 signal
35 Poisoning 17 10.7 10.7 signal
36 Weight Increased 279 9.9 10.9 signal
37 Irritability 75 9.8 10.1 signal
38 Sinus Bradycardia 12 9.8 9.8 signal
39 Thinking Abnormal 23 9.7 9.8 signal
40 Suicidal Ideation 110 9.5 9.9 signal
41 Agitation 88 9.4 9.7 signal
42 Aggression 59 9.3 9.5 signal
43 Mental Status Changes 30 8.5 8.6 signal
44 Blood Creatine Phosphokinase Increased 31 8.4 8.5 signal
45 Cognitive Disorder 49 8.3 8.5 signal
46 Condition Aggravated 318 8.3 9.3 signal
47 Diabetic Ketoacidosis 25 8.2 8.3 signal
48 Muscle Rigidity 12 7.9 8.0 signal
49 Toxicity To Various Agents 166 7.8 8.3 signal
50 Tardive Dyskinesia 28 7.8 7.8 signal
51 Abnormal Behaviour 37 7.3 7.4 signal
52 Salivary Hypersecretion 9 7.1 7.1 signal
53 Drug Level Decreased 9 7.0 7.0 signal
54 Mental Disorder 37 6.7 6.8 signal
55 Hypercholesterolaemia 8 6.6 6.6 signal
56 Muscle Spasticity 10 6.4 6.4 signal
57 Cardio-respiratory Arrest 33 6.2 6.3 signal
58 Delirium 27 6.2 6.2 signal
59 Mydriasis 10 6.2 6.2 signal
60 Cardiac Arrest 64 6.1 6.2 signal
61 Type 2 Diabetes Mellitus 26 6.1 6.1 signal
62 Tachypnoea 10 5.8 5.9 signal
63 Psychomotor Hyperactivity 12 5.7 5.7 signal
64 Hepatomegaly 7 5.6 5.6 signal
65 Sinus Tachycardia 10 5.6 5.6 signal
66 Hepatic Steatosis 13 5.5 5.5 signal
67 Hypotonia 7 5.5 5.5 signal
68 Rhabdomyolysis 29 5.5 5.6 signal
69 Hallucination 52 5.5 5.6 signal
70 Product Prescribing Issue 14 5.4 5.5 signal
71 Disease Recurrence 32 5.3 5.4 signal
72 Tenderness 7 5.3 5.3 signal
73 Intentional Drug Misuse 14 5.2 5.2 signal
74 Activities Of Daily Living Impaired 13 5.1 5.1 signal
75 Hyperglycaemia 23 5.0 5.0 signal
76 Blood Cholesterol Increased 29 4.9 5.0 signal
77 Cardiomyopathy 9 4.8 4.8 signal
78 Inappropriate Antidiuretic Hormone Secretion 6 4.7 4.7 signal
79 Myoclonus 7 4.6 4.6 signal
80 Pancreatitis 31 4.6 4.7 signal
81 Withdrawal Syndrome 23 4.3 4.3 signal
82 Agranulocytosis 10 4.3 4.3 signal
83 Ventricular Fibrillation 6 4.3 4.3 signal
84 Grand Mal Convulsion 5 4.2 4.2 signal
85 Myocarditis 6 4.2 4.2 signal
86 Restlessness 19 4.1 4.1 signal
87 Cyanosis 8 4.0 4.0 signal
88 Thirst 9 4.0 4.0 signal
89 Bladder Disorder 5 4.0 4.0 signal
90 Mood Swings 16 4.0 4.0 signal
91 Tremor 83 3.9 4.0 signal
92 Restless Legs Syndrome 9 3.9 3.9 signal
93 Initial Insomnia 5 3.9 3.9 signal
94 Respiratory Depression 6 3.9 3.9 signal
95 Drug Level Increased 8 3.8 3.8 signal
96 Drug Ineffective 635 3.8 4.7 signal
97 Hallucination, Visual 10 3.8 3.8 signal
98 Sudden Death 5 3.7 3.7 signal
99 Depression 105 3.6 3.7 signal
100 Cold Sweat 8 3.6 3.6 signal
101 Mental Impairment 11 3.6 3.6 signal
102 Fear 12 3.5 3.5 signal
103 Mood Altered 12 3.5 3.5 signal
104 Panic Attack 16 3.5 3.5 signal
105 Neoplasm 5 3.4 3.4 signal
106 Treatment Noncompliance 23 3.3 3.4 signal
107 Speech Disorder 22 3.3 3.3 signal
108 No Therapeutic Response 5 3.2 3.2 signal
109 Product Substitution Issue 23 3.2 3.2 signal
110 Intentional Self-injury 8 3.1 3.1 signal
111 Heart Rate Irregular 9 3.1 3.1 signal
112 Disturbance In Attention 21 3.1 3.1 signal
113 Anger 13 3.0 3.0 signal
114 Breast Pain 4 3.0 3.0 no signal
115 Intentional Overdose 23 2.9 2.9 signal
116 Gynaecomastia 11 2.8 2.8 signal
117 Erectile Dysfunction 9 2.8 2.8 signal
118 Diabetes Mellitus Inadequate Control 6 2.7 2.7 signal
119 Convulsion 19 2.6 2.6 signal
120 Blood Thyroid Stimulating Hormone Increased 3 2.6 2.6 no signal
121 Drug Dispensing Error 5 2.5 2.6 no signal
122 Abasia 8 2.5 2.5 signal
123 Overdose 62 2.3 2.3 signal
124 Amenorrhoea 4 1.9 1.9 no signal
125 Drug Withdrawal Syndrome 21 1.9 1.9 no signal
126 Drug Exposure During Pregnancy 7 1.6 1.6 no signal
127 Abortion Spontaneous 6 1.2 1.2 no signal
128 Drug Abuse 12 1.1 1.1 no signal
129 Wrong Technique In Drug Usage Process 5 1.1 1.1 no signal
130 Drug Dependence 14 0.7 0.7 no signal