Drug

Ziv-aflibercept

36 flagged reaction(s) · 841 total co-reports · max PRR 54.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Proteinuria	64	54.8	57.6	signal
2	Hypertensive Crisis	22	31.8	32.3	signal
3	Mucosal Inflammation	33	20.4	20.9	signal
4	Ileus	15	19.6	19.9	signal
5	Intestinal Perforation	13	18.6	18.8	signal
6	Posterior Reversible Encephalopathy Syndrome	11	18.6	18.8	signal
7	Palmar-plantar Erythrodysaesthesia Syndrome	26	17.9	18.3	signal
8	Hyperbilirubinaemia	11	17.2	17.3	signal
9	Ejection Fraction Decreased	15	15.5	15.7	signal
10	Diarrhoea Haemorrhagic	9	15.5	15.6	signal
11	Neutropenia	105	12.5	13.5	signal
12	Neutrophil Count Decreased	29	11.5	11.8	signal
13	Stomatitis	43	11.4	11.8	signal
14	Metastases To Liver	12	11.0	11.1	signal
15	Rectal Haemorrhage	28	10.5	10.7	signal
16	Hypertension	137	10.4	11.5	signal
17	Bone Marrow Failure	13	10.2	10.3	signal
18	Neurotoxicity	11	10.2	10.3	signal
19	Paraesthesia Oral	9	10.1	10.1	signal
20	Metastases To Lung	7	9.8	9.8	signal
21	Febrile Neutropenia	40	9.7	10.0	signal
22	Ascites	17	9.3	9.4	signal
23	Haematotoxicity	5	8.7	8.7	signal
24	Fistula	6	8.6	8.6	signal
25	Oral Herpes	10	8.3	8.3	signal
26	Intestinal Obstruction	19	8.2	8.3	signal
27	Dysphonia	28	7.7	7.9	signal
28	Ischaemic Stroke	8	7.2	7.2	signal
29	Oral Pain	10	7.2	7.2	signal
30	Polyneuropathy	5	6.8	6.8	signal
31	Disease Progression	49	6.7	6.9	signal
32	Peritonitis	8	6.2	6.3	signal
33	Status Epilepticus	4	5.7	5.7	signal
34	Osteonecrosis Of Jaw	7	4.5	4.5	signal
35	Neoplasm Progression	9	4.1	4.1	signal
36	Bone Loss	3	3.2	3.2	no signal