Reaction
Central Nervous System Necrosis reporting signals
As of the last recalculation, Central Nervous System Necrosis appears in 273 FAERS reports alongside 7 co-occurring drug terms. The strongest observed disproportionality signal is THIOTEPA (PRR 82.8).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Thiotepa | 10 | 82.8 | 82.9 |
| Temozolomide | 19 | 73.8 | 73.9 |
| Polatuzumab Vedotin | 7 | 56.1 | 56.1 |
| Ganciclovir | 7 | 53.5 | 53.5 |
| Ganciclovir Sodium | 7 | 51.7 | 51.8 |
| Bendamustine Hcl | 7 | 35.3 | 35.3 |
| Ethyl Alcohol | 8 | 23.1 | 23.1 |