Drug

Bendamustine Hcl

1,047 flagged reaction(s) · 53,092 total co-reports · max PRR 797.5

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Follicular Lymphoma Refractory	22	797.5	798.6	signal
2	Marginal Zone Lymphoma Recurrent	16	692.2	693.0	signal
3	Lymphatic Duct Injury	7	586.8	587.0	signal
4	Follicular Lymphoma Recurrent	11	245.9	246.1	signal
5	Spleen Atrophy	9	241.4	241.6	signal
6	Splenic Marginal Zone Lymphoma	11	230.5	230.7	signal
7	Follicular Lymphoma	121	225.1	226.9	signal
8	Humoral Immune Defect	52	221.4	222.2	signal
9	Cell-mediated Cytotoxicity	7	218.3	218.4	signal
10	Diffuse Large B-cell Lymphoma Recurrent	293	215.1	219.2	signal
11	Blood Immunoglobulin M Abnormal	14	211.0	211.2	signal
12	B-cell Lymphoma Recurrent	70	201.9	202.8	signal
13	Mantle Cell Lymphoma Recurrent	55	200.5	201.2	signal
14	Fungal Disease Carrier	13	200.4	200.6	signal
15	Ureteric Compression	9	182.9	183.0	signal
16	B-cell Lymphoma Refractory	10	169.8	169.9	signal
17	Lymphoma Transformation	38	160.3	160.7	signal
18	Blood Immunoglobulin G Abnormal	16	148.0	148.1	signal
19	Gastroenteritis Sapovirus	8	135.8	135.9	signal
20	Endocarditis Noninfective	13	131.1	131.2	signal
21	Chronic Lymphocytic Leukaemia Recurrent	59	126.6	127.1	signal
22	Refractory Cancer	17	115.7	115.9	signal
23	Reticulocytopenia	11	111.8	111.8	signal
24	Blood Stem Cell Harvest Failure	11	108.5	108.6	signal
25	Disseminated Toxoplasmosis	8	101.2	101.3	signal
26	Mantle Cell Lymphoma	101	97.0	97.7	signal
27	Vaccine Interaction	20	93.8	93.9	signal
28	Leukaemic Infiltration	9	93.6	93.6	signal
29	Paraneoplastic Pemphigus	8	90.9	91.0	signal
30	Diffuse Large B-cell Lymphoma Refractory	58	90.5	90.8	signal
31	Primary Mediastinal Large B-cell Lymphoma	7	85.3	85.4	signal
32	Leukaemia Cutis	9	83.8	83.9	signal
33	Human Polyomavirus Infection	29	80.4	80.5	signal
34	Breakthrough Covid-19	13	80.3	80.4	signal
35	Primary Amyloidosis	14	79.6	79.6	signal
36	Diffuse Large B-cell Lymphoma	414	78.0	80.1	signal
37	Marginal Zone Lymphoma	11	74.5	74.6	signal
38	Cell-mediated Immune Deficiency	7	71.7	71.7	signal
39	Candida Pneumonia	16	70.6	70.7	signal
40	Cytomegalovirus Syndrome	8	69.7	69.7	signal
41	Cystitis Viral	18	67.4	67.5	signal
42	Jc Virus Infection	68	60.4	60.7	signal
43	High-grade B-cell Lymphoma	8	60.3	60.3	signal
44	Campylobacter Infection	35	59.6	59.7	signal
45	Progressive Multifocal Leukoencephalopathy	321	55.0	56.2	signal
46	Granulomatous Lymphadenitis	7	53.3	53.4	signal
47	Blood Lactate Dehydrogenase Abnormal	25	52.5	52.6	signal
48	Diffuse Large B-cell Lymphoma Stage Iv	12	52.4	52.5	signal
49	Cytomegalovirus Infection Reactivation	156	51.6	52.1	signal
50	Neutropenic Infection	34	49.6	49.7	signal
51	Ilium Fracture	7	48.1	48.2	signal
52	Campylobacter Gastroenteritis	20	47.7	47.8	signal
53	Bone Marrow Infiltration	13	47.4	47.4	signal
54	Peripheral T-cell Lymphoma Unspecified	19	45.5	45.6	signal
55	Blood Uric Acid Abnormal	13	45.2	45.2	signal
56	Babesiosis	9	45.0	45.1	signal
57	Hypertensive Cardiomyopathy	9	44.7	44.7	signal
58	Chronic Lymphocytic Leukaemia	150	44.2	44.6	signal
59	Congenital Aplasia	9	43.6	43.6	signal
60	B-cell Small Lymphocytic Lymphoma	7	43.3	43.3	signal
61	Pneumonia Escherichia	10	43.0	43.0	signal
62	Cytomegalovirus Oesophagitis	11	42.2	42.2	signal
63	Lentigo Maligna	8	41.7	41.8	signal
64	Catheter Site Thrombosis	8	41.6	41.6	signal
65	Cerebral Aspergillosis	18	41.1	41.1	signal
66	Borrelia Infection	9	40.2	40.3	signal
67	Hypogammaglobulinaemia	183	39.9	40.4	signal
68	Interleukin Level Increased	15	39.3	39.3	signal
69	Abdominal Lymphadenopathy	24	39.1	39.2	signal
70	Encephalitis Cytomegalovirus	12	38.8	38.8	signal
71	Hyperviscosity Syndrome	8	38.6	38.6	signal
72	Cytomegalovirus Chorioretinitis	53	38.4	38.5	signal
73	Hyperleukocytosis	23	36.7	36.8	signal
74	Listeria Sepsis	7	36.7	36.7	signal
75	Disseminated Mucormycosis	10	36.0	36.0	signal
76	Skin Neoplasm Excision	20	35.7	35.8	signal
77	Cytomegalovirus Enteritis	9	35.7	35.7	signal
78	Cryoglobulinaemia	18	35.6	35.6	signal
79	Disseminated Varicella Zoster Virus Infection	9	35.6	35.6	signal
80	Central Nervous System Necrosis	7	35.3	35.3	signal
81	Retroperitoneal Lymphadenopathy	13	34.4	34.4	signal
82	Lymphoma	369	33.2	34.0	signal
83	Blood Lactate Dehydrogenase Increased	377	32.9	33.7	signal
84	Gamma-glutamyltransferase Abnormal	14	32.8	32.8	signal
85	Procalcitonin Increased	27	32.6	32.6	signal
86	Vaccination Failure	39	32.5	32.6	signal
87	Pneumonia Pseudomonal	35	32.0	32.1	signal
88	Hepatitis B Reactivation	73	32.0	32.1	signal
89	Hepatitis E	36	31.9	32.0	signal
90	Cytomegalovirus Hepatitis	8	31.5	31.5	signal
91	Immune Effector Cell-associated Neurotoxicity Syndrome	123	30.4	30.7	signal
92	Granuloma Skin	18	30.2	30.2	signal
93	Plasma Cell Leukaemia	13	30.2	30.2	signal
94	Immunoglobulins Decreased	29	29.5	29.5	signal
95	Secondary Immunodeficiency	25	29.1	29.1	signal
96	Tumour Lysis Syndrome	182	28.9	29.3	signal
97	Varicella Zoster Virus Infection	42	28.2	28.3	signal
98	Angiocentric Lymphoma	10	27.9	27.9	signal
99	Hepatitis Viral	16	27.7	27.7	signal
100	B-cell Lymphoma	67	27.2	27.3	signal
101	Pneumocystis Jirovecii Infection	22	26.4	26.5	signal
102	Tumour Flare	13	26.4	26.4	signal
103	Disease Progression	2,242	26.3	30.7	signal
104	Acetabulum Fracture	7	25.7	25.7	signal
105	Cytokine Release Syndrome	352	25.6	26.2	signal
106	Metastatic Lymphoma	7	24.6	24.6	signal
107	Cytomegalovirus Infection	294	24.5	24.9	signal
108	Gastrointestinal Fungal Infection	9	24.3	24.3	signal
109	Infection Reactivation	19	22.9	23.0	signal
110	Serum Sickness	46	22.9	22.9	signal
111	Haematotoxicity	153	22.8	23.0	signal
112	Cytopenia	196	22.7	22.9	signal
113	Blindness Cortical	8	22.6	22.6	signal
114	Hypercreatininaemia	8	22.2	22.2	signal
115	Cerebral Toxoplasmosis	15	22.2	22.2	signal
116	Enterococcal Sepsis	13	22.0	22.0	signal
117	Panniculitis	38	21.8	21.8	signal
118	Chylothorax	11	21.3	21.3	signal
119	Plasma Cell Myeloma Refractory	20	21.3	21.3	signal
120	Neuroendocrine Carcinoma Of The Skin	15	21.2	21.2	signal
121	Myeloproliferative Neoplasm	10	21.1	21.1	signal
122	Pneumonia Cytomegaloviral	29	20.8	20.9	signal
123	Covid-19 Pneumonia	178	20.7	20.9	signal
124	Cytokine Storm	10	20.3	20.3	signal
125	Cytomegalovirus Test Positive	26	20.3	20.3	signal
126	Neutropenic Sepsis	105	20.2	20.4	signal
127	Cytomegalovirus Colitis	33	20.1	20.1	signal
128	Post-acute Covid-19 Syndrome	18	20.1	20.1	signal
129	Blood Bilirubin Decreased	9	20.0	20.0	signal
130	Anosognosia	11	19.6	19.7	signal
131	Enterococcal Bacteraemia	15	19.6	19.6	signal
132	Klebsiella Sepsis	16	19.5	19.6	signal
133	Enterococcal Infection	68	19.4	19.4	signal
134	Ototoxicity	26	19.3	19.4	signal
135	Sinus Polyp	8	19.1	19.1	signal
136	Pneumococcal Sepsis	9	19.0	19.0	signal
137	Hepatitis B	83	18.9	19.0	signal
138	Eastern Cooperative Oncology Group Performance Status Worsened	17	18.8	18.9	signal
139	Therapy Partial Responder	205	18.8	19.0	signal
140	Epstein-barr Virus Associated Lymphoma	8	18.7	18.7	signal
141	Neoplasm Skin	21	18.6	18.6	signal
142	Abdominal Neoplasm	12	18.6	18.6	signal
143	Resorption Bone Increased	11	18.5	18.5	signal
144	Autoimmune Haemolytic Anaemia	45	18.2	18.2	signal
145	Hemianopia	13	17.9	17.9	signal
146	Myelodysplastic Syndrome	183	17.4	17.6	signal
147	Herpes Zoster Disseminated	10	17.4	17.4	signal
148	Pneumonia Mycoplasmal	10	17.3	17.3	signal
149	Plasmacytoma	23	16.8	16.9	signal
150	Hyperuricaemia	50	16.8	16.8	signal
151	Peripheral Motor Neuropathy	17	16.8	16.8	signal
152	Pneumonia Respiratory Syncytial Viral	10	16.7	16.7	signal
153	Lymphocytosis	26	16.7	16.7	signal
154	Lymphopenia	170	16.6	16.8	signal
155	Blood Parathyroid Hormone Decreased	18	16.6	16.6	signal
156	Febrile Neutropenia	797	16.6	17.4	signal
157	Tumour Pseudoprogression	13	16.5	16.5	signal
158	Enterocolitis Infectious	11	16.3	16.3	signal
159	Pneumothorax Spontaneous	8	16.2	16.2	signal
160	Clear Cell Renal Cell Carcinoma	8	16.1	16.1	signal
161	Bone Marrow Toxicity	14	16.0	16.0	signal
162	Encephalitis Viral	14	15.9	15.9	signal
163	Fungal Oesophagitis	8	15.9	15.9	signal
164	Peptic Ulcer Haemorrhage	8	15.9	15.9	signal
165	Aplasia	23	15.8	15.9	signal
166	Blood Immunoglobulin M Increased	7	15.7	15.7	signal
167	Aplasia Pure Red Cell	39	15.6	15.6	signal
168	Vasogenic Cerebral Oedema	8	15.6	15.6	signal
169	Aspergillus Infection	73	15.5	15.5	signal
170	Escherichia Bacteraemia	26	15.5	15.5	signal
171	Pneumocystis Jirovecii Pneumonia	112	15.4	15.5	signal
172	Visceral Leishmaniasis	8	15.4	15.4	signal
173	Bacterial Disease Carrier	8	15.1	15.1	signal
174	Dysplasia	13	15.0	15.0	signal
175	Klebsiella Test Positive	7	14.7	14.7	signal
176	Pelvic Venous Thrombosis	15	14.3	14.3	signal
177	Hilar Lymphadenopathy	9	14.2	14.2	signal
178	Pneumonia Fungal	40	14.2	14.2	signal
179	Neoplasm Recurrence	35	14.1	14.2	signal
180	Lung Adenocarcinoma	31	14.1	14.1	signal
181	Acute Graft Versus Host Disease In Skin	28	13.9	14.0	signal
182	Pulmonary Mycosis	8	13.9	13.9	signal
183	Atypical Pneumonia	30	13.8	13.8	signal
184	Listeriosis	11	13.7	13.7	signal
185	Mucosal Erosion	9	13.6	13.6	signal
186	H1n1 Influenza	14	13.6	13.6	signal
187	Bronchopulmonary Aspergillosis	76	13.5	13.6	signal
188	Lymphocyte Count Decreased	173	13.4	13.6	signal
189	Fat Tissue Increased	14	13.2	13.2	signal
190	Febrile Infection	11	13.1	13.1	signal
191	Second Primary Malignancy	79	13.0	13.1	signal
192	Hypercalcaemia	112	12.5	12.5	signal
193	Adenocarcinoma Of Colon	17	12.4	12.5	signal
194	Metastasis	63	12.0	12.1	signal
195	Subclavian Vein Thrombosis	10	12.0	12.0	signal
196	Epstein-barr Virus Infection Reactivation	11	11.9	11.9	signal
197	Bone Marrow Disorder	26	11.8	11.9	signal
198	Neutropenia	1,169	11.8	12.7	signal
199	Thrombocytopenia	950	11.7	12.4	signal
200	Metastases To Meninges	19	11.6	11.6	signal
201	Dermatitis Exfoliative Generalised	29	11.6	11.6	signal
202	Anaemia Haemolytic Autoimmune	7	11.4	11.4	signal
203	Actinomycosis	8	11.4	11.4	signal
204	Skin Toxicity	46	11.3	11.3	signal
205	Pancytopenia	458	11.3	11.6	signal
206	Peripheral Nerve Injury	7	11.0	11.0	signal
207	Escherichia Sepsis	23	10.9	10.9	signal
208	Cd4 Lymphocytes Decreased	17	10.8	10.8	signal
209	Lymphadenitis	19	10.8	10.8	signal
210	Osteolysis	16	10.7	10.7	signal
211	Demyelinating Polyneuropathy	8	10.6	10.6	signal
212	Hepatosplenomegaly	20	10.6	10.6	signal
213	Malignant Pleural Effusion	13	10.6	10.6	signal
214	Soft Tissue Infection	14	10.6	10.6	signal
215	Systemic Mycosis	9	10.6	10.6	signal
216	Fungaemia	12	10.5	10.5	signal
217	Pneumonia Bacterial	70	10.5	10.5	signal
218	Plasma Cell Myeloma	299	10.5	10.7	signal
219	Pulmonary Sepsis	11	10.4	10.4	signal
220	Pneumonia Viral	24	10.3	10.3	signal
221	Acute Myeloid Leukaemia	117	10.3	10.4	signal
222	Guillain-barre Syndrome	36	10.2	10.2	signal
223	Jugular Vein Thrombosis	13	10.1	10.1	signal
224	Granulocyte Count Decreased	13	10.0	10.0	signal
225	Oral Fungal Infection	20	10.0	10.0	signal
226	Gastrointestinal Toxicity	34	9.9	9.9	signal
227	Systemic Infection	12	9.9	9.9	signal
228	Biliary Obstruction	9	9.8	9.9	signal
229	Squamous Cell Carcinoma Of Skin	43	9.8	9.8	signal
230	Pneumocystis Jiroveci Pneumonia	16	9.7	9.7	signal
231	Troponin T Increased	9	9.7	9.7	signal
232	Acute Febrile Neutrophilic Dermatosis	16	9.5	9.5	signal
233	Suspected Off Label Use	12	9.5	9.5	signal
234	Systemic Candida	17	9.4	9.4	signal
235	Lymphadenopathy Mediastinal	13	9.4	9.4	signal
236	Carotid Arteriosclerosis	7	9.4	9.4	signal
237	Polyneuropathy	81	9.3	9.4	signal
238	Organising Pneumonia	33	9.2	9.2	signal
239	Lymphadenopathy	236	9.1	9.2	signal
240	Pseudomonas Infection	56	9.1	9.1	signal
241	Neurological Decompensation	15	9.0	9.0	signal
242	Radiation Injury	7	9.0	9.0	signal
243	Acinetobacter Infection	7	8.8	8.8	signal
244	Rheumatoid Nodule	18	8.8	8.8	signal
245	Hydronephrosis	48	8.8	8.8	signal
246	Venoocclusive Disease	16	8.7	8.7	signal
247	Arrhythmia Supraventricular	7	8.7	8.7	signal
248	Escherichia Urinary Tract Infection	27	8.7	8.7	signal
249	Neoplasm	73	8.7	8.7	signal
250	Neutropenic Colitis	13	8.6	8.6	signal
251	Histiocytosis Haematophagic	19	8.6	8.6	signal
252	Bone Marrow Failure	129	8.6	8.7	signal
253	Bacteraemia	74	8.6	8.6	signal
254	Pseudomonal Sepsis	11	8.5	8.5	signal
255	Adenocarcinoma	14	8.5	8.5	signal
256	Klebsiella Infection	31	8.4	8.5	signal
257	Clostridium Difficile Colitis	65	8.4	8.4	signal
258	Basal Cell Carcinoma	95	8.3	8.4	signal
259	Nephrogenic Diabetes Insipidus	7	8.3	8.3	signal
260	Rhinovirus Infection	23	8.3	8.3	signal
261	Retinitis	10	8.2	8.2	signal
262	Septic Shock	258	8.2	8.3	signal
263	Haemolytic Anaemia	53	8.1	8.1	signal
264	Splenomegaly	69	8.1	8.1	signal
265	Escherichia Infection	48	8.0	8.0	signal
266	Nocardiosis	15	8.0	8.0	signal
267	Leukopenia	292	8.0	8.1	signal
268	Pseudomembranous Colitis	13	7.9	7.9	signal
269	Hypoalbuminaemia	44	7.9	7.9	signal
270	Otitis Media	19	7.8	7.8	signal
271	Product Ineffective For Unapproved Use	8	7.8	7.8	signal
272	Clostridium Colitis	7	7.8	7.8	signal
273	Osteosclerosis	9	7.8	7.8	signal
274	Myelosuppression	193	7.8	7.8	signal
275	Peripheral Sensorimotor Neuropathy	7	7.7	7.7	signal
276	Paraparesis	10	7.6	7.7	signal
277	Neutrophil Count Decreased	226	7.6	7.7	signal
278	Oesophageal Candidiasis	22	7.6	7.6	signal
279	Intraductal Proliferative Breast Lesion	7	7.6	7.6	signal
280	Neoplasm Progression	191	7.4	7.5	signal
281	Gastrointestinal Obstruction	13	7.4	7.4	signal
282	Urosepsis	50	7.4	7.4	signal
283	Adjustment Disorder	7	7.3	7.3	signal
284	Agranulocytosis	99	7.3	7.4	signal
285	Infectious Pleural Effusion	8	7.2	7.2	signal
286	Infected Skin Ulcer	10	7.2	7.2	signal
287	Non-hodgkin's Lymphoma	7	7.2	7.2	signal
288	Cytomegalovirus Viraemia	23	7.2	7.2	signal
289	Rash Maculo-papular	116	7.2	7.2	signal
290	Acute Sinusitis	9	7.1	7.1	signal
291	Bacterial Sepsis	17	7.1	7.1	signal
292	Toxic Skin Eruption	52	7.0	7.1	signal
293	Pneumonitis	139	7.0	7.1	signal
294	Peripheral Sensory Neuropathy	30	7.0	7.0	signal
295	Central Nervous System Lymphoma	7	7.0	7.0	signal
296	Squamous Cell Carcinoma	48	7.0	7.0	signal
297	Mucosal Inflammation	132	6.9	7.0	signal
298	Graft Versus Host Disease In Skin	11	6.8	6.8	signal
299	Cystitis Haemorrhagic	20	6.8	6.8	signal
300	Blood Immunoglobulin G Decreased	12	6.7	6.7	signal
301	Inflammatory Marker Increased	24	6.7	6.7	signal
302	Capillary Leak Syndrome	10	6.7	6.7	signal
303	Breath Sounds Abnormal	24	6.6	6.7	signal
304	Tachyarrhythmia	12	6.6	6.6	signal
305	Brain Abscess	12	6.5	6.5	signal
306	Leukaemia Recurrent	8	6.5	6.5	signal
307	Neurotoxicity	82	6.4	6.5	signal
308	Spleen Disorder	8	6.4	6.4	signal
309	Monocyte Count Increased	17	6.4	6.4	signal
310	Lung Consolidation	13	6.3	6.3	signal
311	Skin Necrosis	24	6.3	6.3	signal
312	Post Transplant Lymphoproliferative Disorder	23	6.3	6.3	signal
313	Haemophagocytic Lymphohistiocytosis	33	6.2	6.2	signal
314	Genital Herpes	7	6.2	6.2	signal
315	Gene Mutation	9	6.2	6.2	signal
316	Venoocclusive Liver Disease	22	6.1	6.1	signal
317	Paresis	10	6.1	6.1	signal
318	Staphylococcal Sepsis	22	6.1	6.1	signal
319	Therapy Non-responder	197	6.0	6.1	signal
320	Quadriplegia	9	6.0	6.0	signal
321	Urinary Tract Infection Bacterial	11	6.0	6.0	signal
322	Candida Infection	73	6.0	6.0	signal
323	Atrial Flutter	35	6.0	6.0	signal
324	Ventricular Hypokinesia	14	5.9	5.9	signal
325	Herpes Simplex	28	5.9	5.9	signal
326	Opportunistic Infection	8	5.9	5.9	signal
327	Lung Opacity	11	5.8	5.8	signal
328	Bacterial Infection	79	5.8	5.8	signal
329	Neutrophil Count Abnormal	12	5.8	5.8	signal
330	Nephropathy Toxic	47	5.8	5.8	signal
331	Sepsis	470	5.7	5.9	signal
332	C-reactive Protein Increased	153	5.7	5.8	signal
333	Covid-19	744	5.7	6.0	signal
334	Enterocolitis	24	5.7	5.7	signal
335	Left Ventricular Dysfunction	28	5.7	5.7	signal
336	Drug Resistance	107	5.7	5.7	signal
337	Erysipelas	21	5.7	5.7	signal
338	Blood Creatinine Decreased	13	5.7	5.7	signal
339	Graft Versus Host Disease	30	5.7	5.7	signal
340	Haemolysis	32	5.6	5.7	signal
341	Hepatorenal Syndrome	7	5.6	5.6	signal
342	Abdominal Mass	11	5.6	5.6	signal
343	Cardiac Dysfunction	15	5.6	5.6	signal
344	Lymphoproliferative Disorder	12	5.6	5.6	signal
345	Blood Creatinine Abnormal	14	5.6	5.6	signal
346	Encephalitis	28	5.5	5.5	signal
347	Amyloidosis	7	5.5	5.5	signal
348	Anaemia	773	5.5	5.8	signal
349	Infection	577	5.5	5.6	signal
350	Malignant Neoplasm Progression	407	5.5	5.6	signal
351	Metastases To Peritoneum	10	5.4	5.5	signal
352	Blood Disorder	32	5.4	5.5	signal
353	Immune-mediated Enterocolitis	14	5.4	5.4	signal
354	Embolism	33	5.4	5.4	signal
355	Infusion Related Reaction	258	5.3	5.4	signal
356	Multiple Organ Dysfunction Syndrome	108	5.3	5.3	signal
357	Skin Infection	43	5.3	5.3	signal
358	Actinic Keratosis	10	5.2	5.2	signal
359	Febrile Bone Marrow Aplasia	16	5.2	5.2	signal
360	Venous Thrombosis	15	5.2	5.2	signal
361	Immune Reconstitution Inflammatory Syndrome	19	5.2	5.2	signal
362	Dermatitis Exfoliative	19	5.1	5.1	signal
363	Acute Generalised Exanthematous Pustulosis	29	5.1	5.1	signal
364	Chronic Sinusitis	14	5.1	5.1	signal
365	Gastrointestinal Stromal Tumour	10	5.1	5.1	signal
366	Areflexia	10	5.1	5.1	signal
367	Liver Abscess	12	5.0	5.1	signal
368	Neurological Symptom	21	5.0	5.1	signal
369	Human Herpesvirus 6 Infection	7	5.0	5.0	signal
370	Type Iv Hypersensitivity Reaction	10	5.0	5.0	signal
371	Red Cell Distribution Width Increased	15	4.9	4.9	signal
372	Non-small Cell Lung Cancer	17	4.9	4.9	signal
373	Bk Virus Infection	12	4.9	4.9	signal
374	Neck Mass	10	4.8	4.8	signal
375	Cachexia	18	4.8	4.8	signal
376	Clostridial Infection	12	4.8	4.8	signal
377	Skin Mass	23	4.7	4.7	signal
378	Renal Tubular Necrosis	34	4.7	4.7	signal
379	Bronchopneumonia	12	4.7	4.7	signal
380	Protein Total Increased	9	4.6	4.6	signal
381	Plasma Cell Myeloma Recurrent	11	4.6	4.6	signal
382	Varicella	8	4.5	4.5	signal
383	Large Intestinal Ulcer	9	4.5	4.5	signal
384	Atrial Tachycardia	7	4.5	4.5	signal
385	Glomerular Filtration Rate Decreased	40	4.5	4.5	signal
386	Rheumatoid Factor Positive	19	4.5	4.5	signal
387	Exophthalmos	7	4.5	4.5	signal
388	Staphylococcal Bacteraemia	14	4.4	4.4	signal
389	Intentional Product Use Issue	281	4.4	4.4	signal
390	Hepatic Cytolysis	39	4.4	4.4	signal
391	Cardiomyopathy	47	4.3	4.3	signal
392	Systemic Inflammatory Response Syndrome	12	4.3	4.3	signal
393	Non-cardiac Chest Pain	10	4.3	4.3	signal
394	Erythema Nodosum	11	4.3	4.3	signal
395	Spinal Column Injury	7	4.3	4.3	signal
396	Hypophosphataemia	23	4.3	4.3	signal
397	Phlebitis	16	4.3	4.3	signal
398	Lung Infection	49	4.2	4.2	signal
399	Metabolic Disorder	18	4.2	4.2	signal
400	Colitis	116	4.2	4.2	signal
401	Hepatitis Toxic	8	4.2	4.2	signal
402	Disease Recurrence	145	4.1	4.2	signal
403	Neuropathy Peripheral	287	4.1	4.2	signal
404	Pyrexia	1,047	4.1	4.4	signal
405	Cardiac Failure Acute	20	4.1	4.1	signal
406	Haemolytic Uraemic Syndrome	7	4.1	4.1	signal
407	Eosinophilia	52	4.1	4.1	signal
408	C-reactive Protein Abnormal	19	4.0	4.0	signal
409	Prostatitis	9	4.0	4.0	signal
410	Drug Tolerance	15	4.0	4.0	signal
411	Shock Haemorrhagic	24	4.0	4.0	signal
412	Hepatic Cyst	10	4.0	4.0	signal
413	Protein Total Decreased	11	4.0	4.0	signal
414	Lung Infiltration	26	4.0	4.0	signal
415	Immune Thrombocytopenia	13	4.0	4.0	signal
416	Cholestasis	55	3.9	3.9	signal
417	Fungal Infection	95	3.9	3.9	signal
418	Bronchitis Chronic	7	3.9	3.9	signal
419	Oesophageal Ulcer	11	3.9	3.9	signal
420	Generalised Oedema	35	3.9	3.9	signal
421	Herpes Zoster	163	3.9	3.9	signal
422	Haematocrit Decreased	56	3.8	3.8	signal
423	Hyperthermia	21	3.8	3.8	signal
424	Blood Uric Acid Increased	16	3.8	3.8	signal
425	Pathological Fracture	14	3.8	3.8	signal
426	Abdominal Infection	7	3.7	3.7	signal
427	Epstein-barr Virus Infection	17	3.7	3.7	signal
428	Drug Eruption	48	3.7	3.7	signal
429	Acute Respiratory Failure	52	3.7	3.7	signal
430	Failure To Thrive	14	3.7	3.7	signal
431	Ileus	33	3.7	3.7	signal
432	Platelet Count Decreased	285	3.6	3.7	signal
433	Leukoencephalopathy	10	3.6	3.6	signal
434	Aplastic Anaemia	14	3.6	3.6	signal
435	Aspartate Aminotransferase Increased	141	3.6	3.6	signal
436	Angiopathy	15	3.6	3.6	signal
437	Hepatic Necrosis	10	3.6	3.6	signal
438	Renal Cell Carcinoma	13	3.6	3.6	signal
439	Pneumonia	843	3.6	3.7	signal
440	Atrial Fibrillation	253	3.5	3.6	signal
441	Pleural Effusion	157	3.5	3.5	signal
442	Vasculitis	30	3.5	3.5	signal
443	Viral Load Increased	10	3.5	3.5	signal
444	Thrombophlebitis	9	3.5	3.5	signal
445	Acute Respiratory Distress Syndrome	45	3.5	3.5	signal
446	Bronchiolitis	9	3.5	3.5	signal
447	Immunosuppression	22	3.5	3.5	signal
448	Cholecystitis Infective	7	3.4	3.4	signal
449	Pulmonary Function Test Decreased	11	3.4	3.4	signal
450	Adenovirus Infection	7	3.3	3.3	signal
451	Herpes Virus Infection	14	3.3	3.3	signal
452	Alanine Aminotransferase Increased	148	3.3	3.3	signal
453	Respiratory Tract Infection	62	3.3	3.3	signal
454	Immunodeficiency	35	3.2	3.2	signal
455	White Blood Cell Count Decreased	257	3.2	3.3	signal
456	Respiratory Failure	172	3.2	3.2	signal
457	General Physical Condition Abnormal	16	3.2	3.2	signal
458	Performance Status Decreased	11	3.2	3.2	signal
459	Off Label Use	2,037	3.2	3.5	signal
460	Neutrophil Count Increased	24	3.2	3.2	signal
461	Platelet Count Abnormal	14	3.2	3.2	signal
462	Transaminases Increased	51	3.1	3.1	signal
463	Blood Creatinine Increased	149	3.1	3.1	signal
464	Drug Reaction With Eosinophilia And Systemic Symptoms	58	3.1	3.1	signal
465	General Physical Health Deterioration	259	3.1	3.1	signal
466	Appendicectomy	8	3.1	3.1	signal
467	Polymyalgia Rheumatica	7	3.1	3.1	signal
468	Azotaemia	9	3.1	3.1	signal
469	Hepatomegaly	22	3.0	3.0	signal
470	Organ Failure	9	3.0	3.0	signal
471	Recurrent Cancer	9	3.0	3.0	signal
472	Hypernatraemia	11	3.0	3.0	signal
473	Blood Bilirubin Increased	60	3.0	3.0	signal
474	Vascular Device Infection	10	3.0	3.0	signal
475	Hepatotoxicity	49	3.0	3.0	signal
476	Hypertransaminasaemia	15	3.0	3.0	signal
477	White Blood Cell Count Abnormal	14	3.0	3.0	signal
478	Haemoglobin Abnormal	14	3.0	3.0	signal
479	Hyperpyrexia	9	3.0	3.0	signal
480	Thrombotic Microangiopathy	21	3.0	3.0	signal
481	Acute Graft Versus Host Disease	10	2.9	3.0	signal
482	Hypomagnesaemia	30	2.9	2.9	signal
483	Hypokalaemia	98	2.9	2.9	signal
484	Disseminated Intravascular Coagulation	30	2.9	2.9	signal
485	Rhinitis	17	2.9	2.9	signal
486	Hypovolaemic Shock	10	2.9	2.9	signal
487	Serum Ferritin Increased	11	2.9	2.9	signal
488	Hypotonia	21	2.9	2.9	signal
489	Pulmonary Fibrosis	40	2.9	2.9	signal
490	Acute Kidney Injury	318	2.8	2.9	signal
491	Electrolyte Imbalance	24	2.8	2.8	signal
492	Hepatic Lesion	9	2.8	2.8	signal
493	Red Blood Cell Sedimentation Rate Increased	23	2.8	2.8	signal
494	Interstitial Lung Disease	100	2.8	2.8	signal
495	Cardiac Failure	165	2.8	2.8	signal
496	Hypovolaemia	12	2.8	2.8	signal
497	Left Ventricular Failure	7	2.8	2.8	signal
498	Prostatomegaly	8	2.8	2.8	signal
499	Cardiotoxicity	18	2.8	2.8	signal
500	Body Temperature Increased	41	2.7	2.7	signal
501	Mass	28	2.7	2.7	signal
502	Pulmonary Toxicity	14	2.7	2.7	signal
503	Leukocytosis	36	2.7	2.7	signal
504	Acute Pulmonary Oedema	11	2.7	2.7	signal
505	Subdural Haematoma	28	2.7	2.7	signal
506	Ulcer	31	2.6	2.7	signal
507	Meningitis	13	2.6	2.7	signal
508	Hyperbilirubinaemia	20	2.6	2.6	signal
509	Chronic Graft Versus Host Disease	7	2.6	2.6	signal
510	Hyperkalaemia	67	2.6	2.6	signal
511	Granulocytopenia	11	2.6	2.6	signal
512	Acute Hepatic Failure	26	2.6	2.6	signal
513	Multiple Myeloma	9	2.6	2.6	signal
514	Enteritis	12	2.6	2.6	signal
515	Hepatitis C	23	2.6	2.6	signal
516	Cardiac Failure Chronic	8	2.6	2.6	signal
517	Subcutaneous Abscess	9	2.6	2.6	signal
518	Chills	220	2.6	2.6	signal
519	Intestinal Perforation	21	2.5	2.5	signal
520	Hypoxia	65	2.5	2.5	signal
521	Gingivitis	10	2.5	2.5	signal
522	Skin Reaction	26	2.5	2.5	signal
523	Petechiae	19	2.5	2.5	signal
524	Fluid Intake Reduced	9	2.5	2.5	signal
525	Abdominal Abscess	8	2.5	2.5	signal
526	Diabetic Neuropathy	9	2.5	2.5	signal
527	Bronchiectasis	12	2.5	2.5	signal
528	Hepatitis	46	2.4	2.5	signal
529	Drug Ineffective For Unapproved Indication	100	2.4	2.5	signal
530	Gastrointestinal Infection	16	2.4	2.4	signal
531	Metastases To Lymph Nodes	12	2.4	2.4	signal
532	Cardiopulmonary Failure	7	2.4	2.4	signal
533	Colitis Ischaemic	12	2.4	2.4	signal
534	Gastroenteritis	26	2.4	2.4	signal
535	Oral Disorder	13	2.4	2.4	signal
536	Ataxia	21	2.4	2.4	signal
537	Ill-defined Disorder	107	2.4	2.4	signal
538	Atelectasis	17	2.4	2.4	signal
539	Cerebral Ischaemia	9	2.4	2.4	signal
540	Respiratory Syncytial Virus Infection	15	2.4	2.4	signal
541	Anaphylactoid Reaction	7	2.3	2.3	signal
542	Clostridium Difficile Infection	37	2.3	2.3	signal
543	Goitre	7	2.3	2.3	signal
544	Purpura	15	2.3	2.3	signal
545	Odynophagia	10	2.3	2.3	signal
546	Sarcoidosis	8	2.3	2.3	signal
547	Night Sweats	54	2.3	2.3	signal
548	Congestive Cardiomyopathy	7	2.3	2.3	no signal
549	Tubulointerstitial Nephritis	31	2.3	2.3	signal
550	Hypocalcaemia	31	2.2	2.2	signal
551	Pulmonary Tuberculosis	7	2.2	2.2	no signal
552	Aortic Valve Incompetence	7	2.2	2.2	no signal
553	Malignant Melanoma	22	2.2	2.2	signal
554	Inguinal Hernia	10	2.2	2.2	signal
555	Encephalopathy	40	2.2	2.2	signal
556	Upper Respiratory Tract Infection	75	2.2	2.2	signal
557	Hyperglycaemia	59	2.2	2.2	signal
558	Gamma-glutamyltransferase Increased	36	2.2	2.2	signal
559	Streptococcal Infection	9	2.2	2.2	signal
560	Oral Candidiasis	21	2.2	2.2	signal
561	Diverticulum Intestinal	7	2.2	2.2	no signal
562	Prescribed Underdose	32	2.2	2.2	signal
563	Deafness	42	2.2	2.2	signal
564	Skin Lesion	43	2.1	2.2	signal
565	Ileus Paralytic	7	2.1	2.1	no signal
566	End Stage Renal Disease	29	2.1	2.1	signal
567	Haemoglobin Decreased	160	2.1	2.1	signal
568	Hepatocellular Injury	22	2.1	2.1	signal
569	Dermatitis	32	2.1	2.1	signal
570	Multi-organ Failure	27	2.1	2.1	signal
571	Pulmonary Haemorrhage	12	2.1	2.1	signal
572	Facial Paralysis	13	2.1	2.1	signal
573	Ascites	45	2.1	2.1	signal
574	Polyarthritis	8	2.1	2.1	no signal
575	Chronic Myeloid Leukaemia	7	2.1	2.1	no signal
576	Behaviour Disorder	8	2.1	2.1	no signal
577	Viral Infection	50	2.0	2.1	signal
578	Hypotension	301	2.0	2.1	signal
579	Coronavirus Infection	10	2.0	2.0	signal
580	Pericardial Effusion	34	2.0	2.0	signal
581	Polyuria	12	2.0	2.0	no signal
582	Product Use In Unapproved Indication	356	2.0	2.0	no signal
583	Hepatic Failure	44	2.0	2.0	no signal
584	Ischaemic Stroke	26	2.0	2.0	no signal
585	Stomatitis	88	2.0	2.0	no signal
586	Lung Disorder	71	2.0	2.0	no signal
587	Oliguria	9	2.0	2.0	no signal
588	Anaphylactic Shock	37	2.0	2.0	no signal
589	Renal Failure	193	2.0	2.0	no signal
590	Acute Coronary Syndrome	12	2.0	2.0	no signal
591	Blood Sodium Decreased	27	2.0	2.0	no signal
592	Pulmonary Alveolar Haemorrhage	8	1.9	1.9	no signal
593	Conjunctivitis	26	1.9	1.9	no signal
594	Bronchospasm	20	1.9	1.9	no signal
595	Blood Albumin Decreased	11	1.9	1.9	no signal
596	Pneumothorax	22	1.9	1.9	no signal
597	Acute Myocardial Infarction	41	1.9	1.9	no signal
598	Deep Vein Thrombosis	89	1.9	1.9	no signal
599	Benign Prostatic Hyperplasia	7	1.8	1.8	no signal
600	Ejection Fraction Decreased	21	1.8	1.8	no signal
601	Compression Fracture	7	1.8	1.8	no signal
602	Staphylococcal Infection	44	1.8	1.8	no signal
603	Dermatitis Acneiform	8	1.8	1.8	no signal
604	Ecchymosis	9	1.8	1.8	no signal
605	Anal Abscess	7	1.8	1.8	no signal
606	Small Intestinal Obstruction	16	1.8	1.8	no signal
607	Nodule	17	1.8	1.8	no signal
608	Lower Respiratory Tract Infection	59	1.8	1.8	no signal
609	Stevens-johnson Syndrome	29	1.8	1.8	no signal
610	Pulmonary Embolism	124	1.8	1.8	no signal
611	Nonspecific Reaction	7	1.8	1.8	no signal
612	Device Related Infection	20	1.8	1.8	no signal
613	Liver Disorder	57	1.8	1.8	no signal
614	Hepatic Encephalopathy	12	1.7	1.7	no signal
615	Dermatitis Allergic	16	1.7	1.7	no signal
616	Renal Impairment	106	1.7	1.7	no signal
617	Retinal Haemorrhage	9	1.7	1.7	no signal
618	Cholecystitis	15	1.7	1.7	no signal
619	Malnutrition	14	1.7	1.7	no signal
620	Jaundice	34	1.7	1.7	no signal
621	Intracranial Pressure Increased	7	1.7	1.7	no signal
622	Metastases To Liver	22	1.7	1.7	no signal
623	Necrosis	7	1.7	1.7	no signal
624	Cystitis	40	1.7	1.7	no signal
625	Groin Pain	11	1.7	1.7	no signal
626	Sinus Bradycardia	12	1.7	1.7	no signal
627	Mitral Valve Incompetence	14	1.7	1.7	no signal
628	Myocarditis	14	1.7	1.7	no signal
629	Neutrophilia	7	1.7	1.7	no signal
630	Therapeutic Product Effect Decreased	54	1.7	1.7	no signal
631	Immune System Disorder	16	1.7	1.7	no signal
632	Bone Pain	71	1.6	1.7	no signal
633	Ventricular Tachycardia	20	1.6	1.6	no signal
634	Toxic Epidermal Necrolysis	18	1.6	1.6	no signal
635	Abscess	19	1.6	1.6	no signal
636	Red Blood Cell Count Decreased	34	1.6	1.6	no signal
637	Treatment Failure	97	1.6	1.6	no signal
638	Tachypnoea	16	1.6	1.6	no signal
639	Pulmonary Oedema	52	1.6	1.6	no signal
640	Respiratory Distress	32	1.6	1.6	no signal
641	Ventricular Extrasystoles	12	1.6	1.6	no signal
642	Nervous System Disorder	36	1.6	1.6	no signal
643	Platelet Count Increased	15	1.6	1.6	no signal
644	Tricuspid Valve Incompetence	9	1.5	1.5	no signal
645	Hepatic Function Abnormal	42	1.5	1.5	no signal
646	Drug Intolerance	109	1.5	1.5	no signal
647	Oral Herpes	22	1.5	1.5	no signal
648	Renal Cyst	9	1.5	1.5	no signal
649	Pneumonia Aspiration	28	1.5	1.5	no signal
650	Product Use Issue	210	1.5	1.5	no signal
651	White Blood Cell Count Increased	43	1.5	1.5	no signal
652	Liver Injury	27	1.5	1.5	no signal
653	Therapeutic Response Decreased	67	1.5	1.5	no signal
654	Circulatory Collapse	19	1.5	1.5	no signal
655	Oedema	60	1.5	1.5	no signal
656	Synovitis	20	1.5	1.5	no signal
657	Drug Effective For Unapproved Indication	32	1.5	1.5	no signal
658	Rash Pruritic	59	1.5	1.5	no signal
659	Arrhythmia	52	1.5	1.5	no signal
660	Tooth Abscess	11	1.5	1.5	no signal
661	Pulmonary Mass	16	1.5	1.5	no signal
662	Erythema Multiforme	10	1.5	1.5	no signal
663	Blood Urea Increased	18	1.5	1.5	no signal
664	Dehydration	142	1.4	1.5	no signal
665	Status Epilepticus	12	1.4	1.4	no signal
666	Leukaemia	10	1.4	1.4	no signal
667	Tenderness	11	1.4	1.4	no signal
668	Supraventricular Tachycardia	10	1.4	1.4	no signal
669	Blood Alkaline Phosphatase Increased	26	1.4	1.4	no signal
670	Inflammation	53	1.4	1.4	no signal
671	Metastases To Central Nervous System	13	1.4	1.4	no signal
672	Large Intestine Perforation	7	1.4	1.4	no signal
673	Skin Ulcer	26	1.4	1.4	no signal
674	Oesophagitis	11	1.4	1.4	no signal
675	Face Oedema	17	1.4	1.4	no signal
676	Myositis	9	1.4	1.4	no signal
677	Hiatus Hernia	13	1.4	1.4	no signal
678	Renal Failure Acute	43	1.4	1.4	no signal
679	Hyponatraemia	56	1.4	1.4	no signal
680	Pathogen Resistance	9	1.3	1.3	no signal
681	Delirium	34	1.3	1.3	no signal
682	Hiccups	8	1.3	1.3	no signal
683	No Therapeutic Response	12	1.3	1.3	no signal
684	Folliculitis	10	1.3	1.3	no signal
685	Tachycardia	86	1.3	1.3	no signal
686	Gastrointestinal Disorder	85	1.3	1.3	no signal
687	Urinary Retention	32	1.3	1.3	no signal
688	Pulmonary Hypertension	20	1.3	1.3	no signal
689	Rash	412	1.3	1.3	no signal
690	Syncope	95	1.3	1.3	no signal
691	Palmar-plantar Erythrodysaesthesia Syndrome	22	1.3	1.3	no signal
692	Colon Cancer	14	1.3	1.3	no signal
693	Haemodynamic Instability	7	1.3	1.3	no signal
694	Therapeutic Product Effect Incomplete	66	1.3	1.3	no signal
695	Cardiac Arrest	77	1.3	1.3	no signal
696	Sinus Tachycardia	13	1.2	1.2	no signal
697	Atrioventricular Block	7	1.2	1.2	no signal
698	Gastrointestinal Inflammation	7	1.2	1.2	no signal
699	Mental Status Changes	25	1.2	1.2	no signal
700	Sars-cov-2 Test Positive	12	1.2	1.2	no signal
701	Anaphylactic Reaction	49	1.2	1.2	no signal
702	Eye Infection	10	1.2	1.2	no signal
703	Upper Gastrointestinal Haemorrhage	15	1.2	1.2	no signal
704	Cellulitis	44	1.2	1.2	no signal
705	Central Nervous System Lesion	12	1.2	1.2	no signal
706	Haemorrhage Intracranial	13	1.2	1.2	no signal
707	Hypersensitivity	160	1.2	1.2	no signal
708	Spinal Pain	10	1.2	1.2	no signal
709	Epilepsy	26	1.2	1.2	no signal
710	Proteinuria	16	1.2	1.2	no signal
711	Abdominal Pain	197	1.2	1.2	no signal
712	Coagulopathy	14	1.1	1.1	no signal
713	Eosinophil Count Increased	7	1.1	1.1	no signal
714	Cerebral Haemorrhage	30	1.1	1.1	no signal
715	Gastritis	22	1.1	1.1	no signal
716	Musculoskeletal Disorder	16	1.1	1.1	no signal
717	Blindness	34	1.1	1.1	no signal
718	Gout	15	1.1	1.1	no signal
719	Electrocardiogram Qt Prolonged	30	1.1	1.1	no signal
720	Bronchitis	62	1.1	1.1	no signal
721	Shock	19	1.1	1.1	no signal
722	Diverticulitis	23	1.1	1.1	no signal
723	Cerebral Infarction	20	1.1	1.1	no signal
724	Scar	14	1.1	1.1	no signal
725	Death	702	1.1	1.1	no signal
726	Pyelonephritis	7	1.1	1.1	no signal
727	Anuria	7	1.1	1.1	no signal
728	Mouth Ulceration	17	1.1	1.1	no signal
729	Haematoma	21	1.1	1.1	no signal
730	Urinary Tract Infection	137	1.1	1.1	no signal
731	Intestinal Obstruction	30	1.1	1.1	no signal
732	Blood Calcium Increased	7	1.1	1.1	no signal
733	Diarrhoea	512	1.1	1.1	no signal
734	Peritonitis Bacterial	8	1.1	1.1	no signal
735	Toxicity To Various Agents	133	1.1	1.1	no signal
736	Anal Incontinence	7	1.1	1.1	no signal
737	Drug-induced Liver Injury	24	1.1	1.1	no signal
738	Peritonitis	16	1.1	1.1	no signal
739	Optic Neuritis	7	1.0	1.0	no signal
740	Hemiparesis	13	1.0	1.0	no signal
741	Rash Generalised	20	1.0	1.0	no signal
742	Blood Thyroid Stimulating Hormone Increased	7	1.0	1.0	no signal
743	Rash Papular	17	1.0	1.0	no signal
744	Appendicitis	7	1.0	1.0	no signal
745	Hepatic Enzyme Increased	51	1.0	1.0	no signal
746	Abdominal Pain Lower	19	1.0	1.0	no signal
747	Sudden Death	8	1.0	1.0	no signal
748	Chronic Obstructive Pulmonary Disease	39	1.0	1.0	no signal
749	Sputum Discoloured	7	1.0	1.0	no signal
750	Haemorrhage	77	1.0	1.0	no signal
751	Posterior Reversible Encephalopathy Syndrome	7	1.0	1.0	no signal
752	Drug Ineffective	964	1.0	1.0	no signal
753	Autoimmune Disorder	7	1.0	1.0	no signal
754	Skin Disorder	24	1.0	1.0	no signal
755	Decreased Appetite	167	1.0	1.0	no signal
756	Weight Decreased	199	1.0	1.0	no signal
757	Vomiting	334	1.0	1.0	no signal
758	Haematuria	24	1.0	1.0	no signal
759	Myocardial Ischaemia	8	0.9	0.9	no signal
760	Altered State Of Consciousness	15	0.9	0.9	no signal
761	Aphasia	21	0.9	0.9	no signal
762	Constipation	150	0.9	0.9	no signal
763	Metastases To Lung	8	0.9	0.9	no signal
764	Dyspnoea Exertional	26	0.9	0.9	no signal
765	Hyperthyroidism	10	0.9	0.9	no signal
766	Subarachnoid Haemorrhage	7	0.9	0.9	no signal
767	Dysphagia	64	0.9	0.9	no signal
768	Pancreatitis Acute	15	0.9	0.9	no signal
769	Generalised Tonic-clonic Seizure	11	0.9	0.9	no signal
770	Blood Pressure Decreased	44	0.9	0.9	no signal
771	Sinusitis	68	0.9	0.9	no signal
772	Neuralgia	16	0.9	0.9	no signal
773	Thrombosis	53	0.9	0.9	no signal
774	Oedema Peripheral	80	0.9	0.9	no signal
775	Increased Tendency To Bruise	6	0.9	0.9	no signal
776	Liver Function Test Abnormal	19	0.9	0.9	no signal
777	Dyspnoea	367	0.9	0.9	no signal
778	Confusional State	105	0.9	0.9	no signal
779	Hepatic Cirrhosis	12	0.9	0.9	no signal
780	Pharyngitis	8	0.9	0.9	no signal
781	Flank Pain	6	0.9	0.9	no signal
782	Asthenia	240	0.9	0.9	no signal
783	Erythema	131	0.9	0.9	no signal
784	Productive Cough	30	0.9	0.9	no signal
785	Brain Oedema	8	0.9	0.9	no signal
786	Cardiogenic Shock	9	0.9	0.9	no signal
787	Blood Urine Present	12	0.9	0.9	no signal
788	Neoplasm Malignant	42	0.9	0.9	no signal
789	Obstructive Airways Disorder	7	0.9	0.9	no signal
790	Blood Calcium Decreased	7	0.8	0.8	no signal
791	Rash Erythematous	29	0.8	0.8	no signal
792	Haemorrhoids	12	0.8	0.8	no signal
793	Fluid Overload	9	0.8	0.8	no signal
794	Oxygen Saturation Decreased	34	0.8	0.8	no signal
795	Eating Disorder	13	0.8	0.8	no signal
796	Cough	170	0.8	0.8	no signal
797	Tooth Infection	8	0.8	0.8	no signal
798	Osteonecrosis	20	0.8	0.8	no signal
799	Renal Injury	18	0.8	0.8	no signal
800	Brain Injury	6	0.8	0.8	no signal
801	Hypothermia	6	0.8	0.8	no signal
802	Osteopenia	9	0.8	0.8	no signal
803	Inappropriate Antidiuretic Hormone Secretion	6	0.8	0.8	no signal
804	Influenza	64	0.8	0.8	no signal
805	Respiratory Depression	7	0.8	0.8	no signal
806	Drug Effect Incomplete	21	0.8	0.8	no signal
807	Hypertension	120	0.8	0.8	no signal
808	Cardiomegaly	7	0.8	0.8	no signal
809	Contraindicated Product Administered	17	0.8	0.8	no signal
810	Pemphigus	7	0.8	0.8	no signal
811	Transient Ischaemic Attack	19	0.8	0.8	no signal
812	Decreased Activity	6	0.8	0.8	no signal
813	No Adverse Event	99	0.8	0.8	no signal
814	Skin Cancer	12	0.8	0.8	no signal
815	Fatigue	432	0.8	0.7	no signal
816	Angina Pectoris	16	0.8	0.8	no signal
817	Disorientation	22	0.8	0.8	no signal
818	Wound Infection	6	0.8	0.8	no signal
819	Cholelithiasis	18	0.7	0.7	no signal
820	Gastrointestinal Haemorrhage	46	0.7	0.7	no signal
821	Angioedema	24	0.7	0.7	no signal
822	Ventricular Fibrillation	6	0.7	0.7	no signal
823	Nerve Injury	6	0.7	0.7	no signal
824	Hypertensive Crisis	6	0.7	0.7	no signal
825	Nausea	422	0.7	0.7	no signal
826	Respiratory Disorder	16	0.7	0.7	no signal
827	Depressed Level Of Consciousness	21	0.7	0.7	no signal
828	Gastric Ulcer	10	0.7	0.7	no signal
829	Urticaria	87	0.7	0.7	no signal
830	Osteonecrosis Of Jaw	13	0.7	0.7	no signal
831	Muscular Weakness	59	0.7	0.7	no signal
832	Prostate Cancer	42	0.7	0.7	no signal
833	Orthostatic Hypotension	9	0.7	0.7	no signal
834	Rectal Haemorrhage	22	0.7	0.7	no signal
835	Lung Neoplasm Malignant	21	0.7	0.7	no signal
836	Bradycardia	27	0.7	0.7	no signal
837	Arthropathy	28	0.7	0.7	no signal
838	Tinnitus	23	0.7	0.7	no signal
839	Bursitis	6	0.7	0.7	no signal
840	Seasonal Allergy	7	0.7	0.7	no signal
841	Motor Dysfunction	5	0.7	0.7	no signal
842	Coronary Artery Disease	15	0.7	0.7	no signal
843	Eye Discharge	5	0.7	0.7	no signal
844	Drug Level Decreased	5	0.7	0.7	no signal
845	Paralysis	7	0.7	0.7	no signal
846	Epistaxis	36	0.7	0.7	no signal
847	Pericarditis	8	0.7	0.7	no signal
848	Vertigo	29	0.6	0.6	no signal
849	Meningioma	7	0.6	0.6	no signal
850	Full Blood Count Abnormal	5	0.6	0.6	no signal
851	Pancreatitis	25	0.6	0.6	no signal
852	Tuberculosis	6	0.6	0.6	no signal
853	Blood Potassium Decreased	14	0.6	0.6	no signal
854	Haemoptysis	13	0.6	0.6	no signal
855	Condition Aggravated	140	0.6	0.6	no signal
856	Dysuria	17	0.6	0.6	no signal
857	Pulmonary Thrombosis	5	0.6	0.6	no signal
858	Cardiac Failure Congestive	37	0.6	0.6	no signal
859	Blood Count Abnormal	7	0.6	0.6	no signal
860	Presyncope	11	0.6	0.6	no signal
861	Pruritus	168	0.6	0.6	no signal
862	Type 2 Diabetes Mellitus	15	0.6	0.6	no signal
863	Lactic Acidosis	14	0.6	0.6	no signal
864	Retinal Detachment	4	0.6	0.6	no signal
865	Prostatic Specific Antigen Increased	6	0.6	0.6	no signal
866	Gastric Haemorrhage	5	0.6	0.6	no signal
867	Feeling Cold	12	0.6	0.6	no signal
868	Cardiovascular Disorder	11	0.6	0.6	no signal
869	Nephropathy	4	0.6	0.6	no signal
870	Blindness Unilateral	6	0.6	0.6	no signal
871	Dysarthria	16	0.6	0.6	no signal
872	Impaired Work Ability	9	0.6	0.6	no signal
873	Palpitations	49	0.6	0.6	no signal
874	Paraesthesia	66	0.6	0.6	no signal
875	Therapy Change	4	0.6	0.6	no signal
876	Intervertebral Disc Protrusion	9	0.6	0.6	no signal
877	Blood Pressure Systolic Increased	8	0.6	0.6	no signal
878	Melaena	9	0.6	0.6	no signal
879	Renal Disorder	19	0.6	0.6	no signal
880	Underdose	29	0.5	0.5	no signal
881	Full Blood Count Decreased	8	0.5	0.5	no signal
882	Respiratory Arrest	11	0.5	0.5	no signal
883	Diabetes Mellitus Inadequate Control	7	0.5	0.5	no signal
884	Myalgia	67	0.5	0.5	no signal
885	Cardiac Disorder	37	0.5	0.5	no signal
886	Eyelid Ptosis	4	0.5	0.5	no signal
887	Helicobacter Infection	4	0.5	0.5	no signal
888	Dry Eye	19	0.5	0.5	no signal
889	Temperature Intolerance	4	0.5	0.5	no signal
890	Osteomyelitis	7	0.5	0.5	no signal
891	Skin Exfoliation	32	0.5	0.5	no signal
892	Speech Disorder	20	0.5	0.5	no signal
893	Transfusion	4	0.5	0.5	no signal
894	Renal Pain	4	0.5	0.5	no signal
895	Loss Of Personal Independence In Daily Activities	18	0.5	0.5	no signal
896	Chronic Kidney Disease	29	0.5	0.5	no signal
897	Hypothyroidism	12	0.5	0.5	no signal
898	Ear Infection	10	0.5	0.5	no signal
899	Chest Discomfort	38	0.5	0.5	no signal
900	Uveitis	5	0.5	0.5	no signal
901	Back Pain	86	0.5	0.5	no signal
902	Prescribed Overdose	7	0.5	0.5	no signal
903	Chest Pain	67	0.5	0.5	no signal
904	Ear Pain	7	0.5	0.5	no signal
905	Psychomotor Hyperactivity	6	0.5	0.5	no signal
906	Musculoskeletal Pain	19	0.5	0.5	no signal
907	Arthritis	28	0.5	0.5	no signal
908	Rebound Effect	4	0.5	0.5	no signal
909	Metabolic Acidosis	11	0.5	0.5	no signal
910	Pulmonary Arterial Hypertension	5	0.5	0.5	no signal
911	Post Procedural Haemorrhage	4	0.5	0.5	no signal
912	Eyelid Oedema	4	0.5	0.5	no signal
913	Swelling Face	22	0.5	0.5	no signal
914	Dyspepsia	33	0.5	0.5	no signal
915	Macular Degeneration	4	0.5	0.5	no signal
916	Hyperhidrosis	43	0.5	0.5	no signal
917	Liver Function Test Increased	7	0.4	0.4	no signal
918	Gastrointestinal Carcinoma	3	0.4	0.4	no signal
919	Influenza Like Illness	27	0.4	0.4	no signal
920	Drug Hypersensitivity	63	0.4	0.4	no signal
921	Ovarian Cancer	3	0.4	0.4	no signal
922	Personality Change	3	0.4	0.4	no signal
923	Diarrhoea Haemorrhagic	3	0.4	0.4	no signal
924	Peripheral Swelling	49	0.4	0.4	no signal
925	Poisoning	4	0.4	0.4	no signal
926	Fracture	6	0.4	0.4	no signal
927	International Normalised Ratio Increased	9	0.4	0.4	no signal
928	Gastric Cancer	8	0.4	0.4	no signal
929	Loss Of Consciousness	40	0.4	0.4	no signal
930	Hernia	6	0.4	0.4	no signal
931	Swelling	29	0.4	0.4	no signal
932	Cardio-respiratory Arrest	13	0.4	0.4	no signal
933	Diplopia	8	0.4	0.4	no signal
934	Myocardial Infarction	54	0.4	0.4	no signal
935	Decreased Immune Responsiveness	3	0.4	0.4	no signal
936	Ankylosing Spondylitis	4	0.4	0.4	no signal
937	Laboratory Test Abnormal	9	0.4	0.4	no signal
938	Psychotic Disorder	9	0.4	0.4	no signal
939	Urinary Incontinence	9	0.4	0.4	no signal
940	Adverse Reaction	4	0.4	0.4	no signal
941	Adverse Event	27	0.4	0.4	no signal
942	Poor Venous Access	3	0.4	0.4	no signal
943	Neck Pain	16	0.4	0.4	no signal
944	Blister	16	0.4	0.4	no signal
945	Musculoskeletal Stiffness	25	0.4	0.4	no signal
946	Arthralgia	118	0.4	0.4	no signal
947	Hypersomnia	8	0.4	0.4	no signal
948	Unevaluable Event	21	0.4	0.4	no signal
949	Hypophagia	7	0.4	0.4	no signal
950	Apathy	4	0.4	0.4	no signal
951	Mental Disorder	12	0.4	0.4	no signal
952	Impaired Healing	9	0.4	0.4	no signal
953	Seizure	31	0.4	0.4	no signal
954	Oropharyngeal Pain	25	0.4	0.4	no signal
955	Dysgeusia	20	0.4	0.4	no signal
956	Internal Haemorrhage	3	0.4	0.4	no signal
957	Abdominal Distension	27	0.4	0.4	no signal
958	Pallor	7	0.3	0.3	no signal
959	Head Injury	8	0.3	0.3	no signal
960	Cataract	15	0.3	0.3	no signal
961	Dementia	7	0.3	0.3	no signal
962	Activities Of Daily Living Impaired	5	0.3	0.3	no signal
963	Fall	82	0.3	0.3	no signal
964	Lethargy	14	0.3	0.3	no signal
965	Product Preparation Error	5	0.3	0.3	no signal
966	Tremor	40	0.3	0.3	no signal
967	Drug Interaction	38	0.3	0.3	no signal
968	Road Traffic Accident	10	0.3	0.3	no signal
969	Cognitive Disorder	11	0.3	0.3	no signal
970	Pain	145	0.3	0.3	no signal
971	Cerebrovascular Accident	40	0.3	0.3	no signal
972	Headache	147	0.3	0.3	no signal
973	Alopecia	46	0.3	0.3	no signal
974	Injection Site Induration	3	0.3	0.3	no signal
975	Sleep Disorder	16	0.3	0.3	no signal
976	Sopor	3	0.3	0.3	no signal
977	Wheezing	13	0.3	0.3	no signal
978	Restlessness	8	0.3	0.3	no signal
979	Insomnia	57	0.3	0.3	no signal
980	Hypoaesthesia	32	0.3	0.3	no signal
981	Malaise	93	0.3	0.3	no signal
982	Contusion	20	0.3	0.3	no signal
983	Depression	47	0.3	0.3	no signal
984	Abdominal Pain Upper	42	0.3	0.3	no signal
985	Rheumatoid Arthritis	23	0.3	0.3	no signal
986	Disturbance In Attention	11	0.3	0.3	no signal
987	Heart Rate Increased	20	0.3	0.3	no signal
988	Nasopharyngitis	37	0.3	0.3	no signal
989	Somnolence	40	0.3	0.3	no signal
990	Discomfort	12	0.3	0.3	no signal
991	Memory Impairment	27	0.3	0.3	no signal
992	Visual Impairment	24	0.3	0.3	no signal
993	Pain In Extremity	57	0.3	0.3	no signal
994	Pollakiuria	8	0.3	0.3	no signal
995	Joint Swelling	23	0.3	0.3	no signal
996	Coma	9	0.3	0.3	no signal
997	Dysphonia	11	0.3	0.3	no signal
998	Renal Cancer	9	0.3	0.3	no signal
999	Dizziness	92	0.3	0.2	no signal
1000	Bladder Cancer	11	0.3	0.3	no signal
1001	Diabetes Mellitus	14	0.2	0.2	no signal
1002	Feeling Hot	11	0.2	0.2	no signal
1003	Eczema	9	0.2	0.2	no signal
1004	Flushing	18	0.2	0.2	no signal
1005	Overdose	38	0.2	0.2	no signal
1006	Ocular Hyperaemia	8	0.2	0.2	no signal
1007	Rhinorrhoea	11	0.2	0.2	no signal
1008	Treatment Noncompliance	9	0.2	0.2	no signal
1009	Hepatic Cancer	4	0.2	0.2	no signal
1010	Hypoacusis	7	0.2	0.2	no signal
1011	Agitation	12	0.2	0.2	no signal
1012	Dry Mouth	13	0.2	0.2	no signal
1013	Muscle Spasms	29	0.2	0.2	no signal
1014	Fluid Retention	8	0.2	0.2	no signal
1015	Therapy Cessation	8	0.2	0.2	no signal
1016	Injection Site Reaction	10	0.2	0.2	no signal
1017	Weight Increased	32	0.2	0.2	no signal
1018	Pancreatic Carcinoma	4	0.2	0.2	no signal
1019	Abdominal Discomfort	23	0.2	0.2	no signal
1020	Blood Pressure Increased	21	0.2	0.2	no signal
1021	Hallucination	10	0.2	0.2	no signal
1022	Oesophageal Carcinoma	4	0.2	0.2	no signal
1023	Gait Disturbance	25	0.2	0.2	no signal
1024	Exposure During Pregnancy	8	0.2	0.2	no signal
1025	Breast Cancer	12	0.2	0.2	no signal
1026	Haematochezia	7	0.2	0.2	no signal
1027	Flatulence	7	0.2	0.2	no signal
1028	Convulsion	7	0.2	0.2	no signal
1029	Nasal Congestion	7	0.2	0.2	no signal
1030	Balance Disorder	10	0.2	0.2	no signal
1031	Mobility Decreased	8	0.2	0.2	no signal
1032	Blood Glucose Increased	21	0.2	0.1	no signal
1033	Injection Site Erythema	13	0.1	0.1	no signal
1034	Feeling Abnormal	25	0.1	0.1	no signal
1035	Vision Blurred	14	0.1	0.1	no signal
1036	Anxiety	29	0.1	0.1	no signal
1037	Adverse Drug Reaction	9	0.1	0.1	no signal
1038	Illness	10	0.1	0.1	no signal
1039	Injection Site Rash	3	0.1	0.1	no signal
1040	Dry Skin	13	0.1	0.1	no signal
1041	Gynaecomastia	3	0.1	0.1	no signal
1042	Psoriasis	12	0.1	0.1	no signal
1043	Maternal Exposure During Pregnancy	8	0.1	0.1	no signal
1044	Hospitalisation	12	0.1	0.1	no signal
1045	Injection Site Pain	15	0.1	0.1	no signal
1046	Incorrect Dose Administered	11	0.1	0.1	no signal
1047	Product Dose Omission Issue	9	0.0	0.0	no signal