Reaction

Polysubstance Abuse reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 636 reports · 10 co-occurring drugs

As of the last recalculation, Polysubstance Abuse appears in 636 FAERS reports alongside 10 co-occurring drug terms. The strongest observed disproportionality signal is OXYCODONE HYDROCHLORIDE (PRR 160.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Oxycodone Hydrochloride400160.7161.0
Morphine Sulfate10634.134.1
Carisoprodol1831.731.8
Derma Foam Excel Hand Sanitizer729.029.0
Ethanol728.928.9
Oxymorphone Hydrochloride1028.528.5
Oxycodone Hydrochloride And Acetaminophen6021.821.8
Methadone Hydrochloride618.318.3
Hydrocodone Bitartrate2116.316.3
Amphetamine415.915.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.