Licensed vaccine product
IPOL: side effects, ingredients & package insert
Sanofi Pasteur · polio (IPV) vaccine · inactivated · intramuscular · 0.5 mL
IPOL ingredients (FDA package insert, Section 11)
Per-dose composition as stated in the prescribing information; verified 2026-07-09. Click an ingredient for every vaccine that contains it.
| Role | Ingredient | Amount per dose |
|---|---|---|
| Antigen | Poliovirus Type 1 (Mahoney), inactivated | 40 D-antigen units |
| Antigen | Poliovirus Type 2 (MEF-1), inactivated | 8 D-antigen units |
| Antigen | Poliovirus Type 3 (Saukett), inactivated | 32 D-antigen units |
| Preservative | 2-Phenoxyethanol | 0.5% |
| inactivating_agent_residual | Formaldehyde | max 0.02% |
| culture_medium_residual | M-199 medium components | diluent vehicle |
| antibiotic_residual | Neomycin | trace residual |
| antibiotic_residual | Streptomycin | trace residual |
| antibiotic_residual | Polymyxin B | trace residual |
| residual_manufacturing | Calf serum | trace residual |
Note: Inactivated whole-virus; no aluminum adjuvant.
Source: DailyMed. Formulations change — re-verify before clinical use.
IPOL side effects: where the data is
Reported reactions for IPOL and the other polio (IPV) products are compiled on the polio (IPV) vaccine page: pre-licensure trial reactogenicity, VAERS report counts, and international databases (Canada Vigilance, EudraVigilance, Lareb, VigiAccess). Those counts are spontaneous reports with no denominator — a report does not establish that the vaccine caused the event.
IPOL lot number lookup
VAERS report counts are available by lot for Polio (IPV) vaccines. Use the polio (IPV) lot number lookup or search any lot directly in the lot explorer. Lot numbers are printed on the vaccination record card and the vial label.
Schedule and age range
Licensed ages and the recommended series for polio (IPV) vaccines are on the polio (IPV) vaccine page; how 31 countries schedule it is on polio (IPV) schedule by country. Always confirm the product-specific age range in the current package insert.
Common questions about IPOL
What are the side effects of IPOL?
Common reactions listed in the IPOL package insert are injection-site pain, redness or swelling and short-lived systemic symptoms such as fever, tiredness or irritability. Rarer events and the reported counts from VAERS and international databases are on the polio (IPV) vaccine page; counts are reports, not rates, and do not prove the vaccine caused the event.
What is in IPOL?
IPOL contains Poliovirus Type 1 (Mahoney), inactivated; Poliovirus Type 2 (MEF-1), inactivated; Poliovirus Type 3 (Saukett), inactivated as antigen; adjuvant: none; it is 2-Phenoxyethanol. Excipients: Formaldehyde, M-199 medium components, Neomycin, Streptomycin, Polymyxin B, Calf serum. Amounts per dose are in the table above, taken from Section 11 of the FDA package insert (verified 2026-07-09).
Where is the IPOL package insert?
The FDA-licensed prescribing information for IPOL is published by Sanofi Pasteur and the FDA; the source used for this page is https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=6979f24b-5f49-4190-a4e6-c1523e0d3108. Formulations change, so re-verify the current insert before clinical use.
Reviewed 2026-10-08 · Matthew Thomas J Halma, Founder, Open Source Medicine Foundation. Informational, not medical advice.