OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Alprostadil

157 flagged reaction(s) · 3,689 total co-reports · max PRR 30.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Neutrophil Count Increased 54 30.9 31.3 signal
2 Lymphocyte Count Decreased 79 26.2 26.8 signal
3 Erectile Dysfunction 93 21.2 21.7 signal
4 Blood Urea Increased 59 20.5 20.9 signal
5 Haematotoxicity 20 12.6 12.7 signal
6 Device Failure 27 10.4 10.5 signal
7 Needle Issue 49 10.0 10.2 signal
8 Disseminated Intravascular Coagulation 21 8.7 8.7 signal
9 Arteriosclerosis 14 8.7 8.7 signal
10 Generalised Oedema 18 8.6 8.6 signal
11 Drug Reaction With Eosinophilia And Systemic Symptoms 36 8.2 8.3 signal
12 Lung Infection 22 8.2 8.2 signal
13 Drug Effect Decreased 73 7.8 8.0 signal
14 White Blood Cell Count Increased 51 7.7 7.8 signal
15 Syringe Issue 23 7.7 7.7 signal
16 Caesarean Section 15 7.5 7.5 signal
17 Hyperlipidaemia 15 7.3 7.3 signal
18 Sexual Dysfunction 14 7.0 7.0 signal
19 Toxic Epidermal Necrolysis 18 7.0 7.0 signal
20 Myocardial Ischaemia 13 6.6 6.6 signal
21 Injury Associated With Device 22 6.4 6.4 signal
22 Procedural Pain 29 6.1 6.2 signal
23 Blood Triglycerides Increased 17 5.6 5.6 signal
24 Thrombotic Microangiopathy 9 5.4 5.4 signal
25 Cardiac Failure 73 5.3 5.4 signal
26 C-reactive Protein Increased 33 5.3 5.3 signal
27 Blood Alkaline Phosphatase Increased 21 4.9 5.0 signal
28 Supraventricular Tachycardia 8 4.9 4.9 signal
29 Device Malfunction 55 4.8 4.8 signal
30 Wrong Technique In Drug Usage Process 30 4.8 4.8 signal
31 Haemoglobin Decreased 83 4.7 4.8 signal
32 Motor Dysfunction 8 4.6 4.6 signal
33 Drug Effect Incomplete 29 4.6 4.6 signal
34 Device Mechanical Issue 10 4.5 4.5 signal
35 Product Prescribing Error 18 4.4 4.5 signal
36 Hepatic Function Abnormal 28 4.4 4.4 signal
37 Pulmonary Congestion 10 4.4 4.4 signal
38 Multiple Organ Dysfunction Syndrome 21 4.4 4.4 signal
39 Hypokalaemia 34 4.3 4.4 signal
40 Ischaemic Stroke 13 4.3 4.3 signal
41 Coagulopathy 12 4.2 4.2 signal
42 Prostatic Specific Antigen Increased 10 4.2 4.2 signal
43 Drug Effect Less Than Expected 10 4.1 4.2 signal
44 Shock 16 4.1 4.1 signal
45 Product Quality Issue 92 4.0 4.1 signal
46 Injection Site Haematoma 10 4.0 4.0 signal
47 Injection Site Discomfort 7 4.0 4.0 signal
48 Post Procedural Complication 13 4.0 4.0 signal
49 Ventricular Extrasystoles 7 3.9 3.9 signal
50 Ataxia 8 3.9 3.9 signal
51 Malignant Melanoma 9 3.9 3.9 signal
52 Drug Ineffective 883 3.9 4.9 signal
53 Cytomegalovirus Infection 11 3.9 3.9 signal
54 Pharmaceutical Product Complaint 17 3.8 3.8 signal
55 Pregnancy 13 3.8 3.8 signal
56 Alanine Aminotransferase Increased 39 3.7 3.7 signal
57 Dialysis 9 3.7 3.7 signal
58 Ventricular Fibrillation 7 3.7 3.7 signal
59 Blood Creatinine Increased 41 3.7 3.7 signal
60 Dizziness Postural 6 3.7 3.7 signal
61 Pulmonary Oedema 28 3.7 3.7 signal
62 Drug-induced Liver Injury 19 3.6 3.6 signal
63 Ascites 18 3.6 3.6 signal
64 Blood Cholesterol Increased 28 3.5 3.5 signal
65 Incorrect Product Storage 8 3.5 3.5 signal
66 End Stage Renal Disease 11 3.5 3.5 signal
67 Skin Ulcer 15 3.4 3.4 signal
68 Drug Dispensing Error 9 3.4 3.4 signal
69 Drug Administration Error 18 3.4 3.4 signal
70 Blood Urine Present 11 3.4 3.4 signal
71 Cyanosis 9 3.3 3.3 signal
72 No Therapeutic Response 7 3.3 3.3 signal
73 Premature Baby 17 3.3 3.3 signal
74 Device Defective 9 3.3 3.3 signal
75 Blood Potassium Increased 9 3.2 3.2 signal
76 Haematuria 19 3.2 3.3 signal
77 Blood Bilirubin Increased 15 3.2 3.2 signal
78 Product Dispensing Error 12 3.2 3.2 signal
79 Product Packaging Issue 5 3.2 3.2 signal
80 Therapeutic Product Effect Decreased 23 3.0 3.0 signal
81 Drug Prescribing Error 10 3.0 3.0 signal
82 Multi-organ Failure 9 3.0 3.0 signal
83 Diabetes Mellitus 39 3.0 3.0 signal
84 Haemoptysis 14 2.9 2.9 signal
85 Therapeutic Product Effect Incomplete 35 2.9 2.9 signal
86 Toxic Skin Eruption 5 2.9 2.9 signal
87 Cerebral Infarction 12 2.9 2.9 signal
88 Subarachnoid Haemorrhage 5 2.9 2.9 signal
89 Poor Quality Product Administered 5 2.9 2.9 signal
90 Injection Site Discolouration 6 2.8 2.8 signal
91 Device Breakage 19 2.8 2.8 signal
92 Ventricular Tachycardia 8 2.8 2.8 signal
93 Expired Product Administered 16 2.8 2.8 signal
94 Intentional Drug Misuse 10 2.8 2.8 signal
95 Drug Administered At Inappropriate Site 5 2.7 2.7 no signal
96 Haemorrhage Intracranial 7 2.7 2.7 signal
97 Wound Infection 5 2.7 2.7 no signal
98 Product Use Complaint 7 2.6 2.6 signal
99 Product Administration Error 9 2.6 2.6 signal
100 Prostate Cancer 36 2.6 2.6 signal
101 Injection Site Haemorrhage 35 2.6 2.6 signal
102 Abscess 7 2.6 2.6 signal
103 Incorrect Dose Administered By Device 11 2.5 2.5 signal
104 Coronary Artery Disease 13 2.5 2.5 signal
105 Angina Pectoris 12 2.4 2.4 signal
106 Device Use Issue 7 2.4 2.4 signal
107 Stevens-johnson Syndrome 9 2.4 2.4 signal
108 Body Temperature Decreased 4 2.4 2.4 no signal
109 Interstitial Lung Disease 19 2.3 2.3 signal
110 Hyperbilirubinaemia 4 2.3 2.3 no signal
111 Product Preparation Error 8 2.3 2.3 signal
112 Device Leakage 16 2.2 2.2 signal
113 Device Occlusion 5 2.1 2.1 no signal
114 Obstructive Airways Disorder 4 2.1 2.1 no signal
115 Drug Exposure During Pregnancy 12 2.0 2.0 signal
116 Gastric Haemorrhage 4 2.0 2.0 no signal
117 Blood Glucose Increased 65 2.0 2.0 signal
118 Medication Error 19 2.0 2.0 signal
119 Peritonitis 7 2.0 2.0 no signal
120 Blood Thyroid Stimulating Hormone Increased 3 1.9 1.9 no signal
121 Lymphoma 5 1.9 1.9 no signal
122 Anaphylactic Shock 8 1.8 1.8 no signal
123 Anorexia 4 1.8 1.8 no signal
124 Injection Site Pain 92 1.8 1.8 no signal
125 Inappropriate Antidiuretic Hormone Secretion 3 1.7 1.7 no signal
126 Neurotoxicity 5 1.7 1.7 no signal
127 Wrong Technique In Device Usage Process 13 1.7 1.7 no signal
128 Cardiovascular Disorder 7 1.6 1.6 no signal
129 Blood Glucose Fluctuation 3 1.6 1.6 no signal
130 Drug Resistance 7 1.6 1.6 no signal
131 Myocarditis 3 1.5 1.5 no signal
132 Bone Marrow Failure 5 1.4 1.4 no signal
133 Libido Decreased 3 1.4 1.4 no signal
134 Injection Site Induration 3 1.4 1.4 no signal
135 Incorrect Dose Administered 50 1.3 1.3 no signal
136 Wrong Technique In Product Usage Process 44 1.3 1.3 no signal
137 Diabetic Ketoacidosis 5 1.2 1.2 no signal
138 Pulmonary Arterial Hypertension 3 1.2 1.2 no signal
139 Myelosuppression 7 1.2 1.2 no signal
140 Dystonia 4 1.2 1.2 no signal
141 Drug Effective For Unapproved Indication 6 1.2 1.2 no signal
142 Device Delivery System Issue 5 1.1 1.1 no signal
143 Application Site Pain 4 1.1 1.1 no signal
144 Circumstance Or Information Capable Of Leading To Medication Error 6 1.0 1.0 no signal
145 Tardive Dyskinesia 5 1.0 1.0 no signal
146 Product Storage Error 15 1.0 1.0 no signal
147 Device Issue 15 1.0 1.0 no signal
148 Injection Site Mass 6 1.0 1.0 no signal
149 Product Complaint 4 0.9 0.9 no signal
150 Bladder Cancer 9 0.9 0.9 no signal
151 Exposure Via Skin Contact 3 0.8 0.8 no signal
152 Gynaecomastia 4 0.7 0.7 no signal
153 Device Use Error 4 0.7 0.7 no signal
154 Device Difficult To Use 7 0.6 0.6 no signal
155 Drug Dependence 13 0.5 0.5 no signal
156 Drug Dose Omission By Device 5 0.4 0.4 no signal
157 Dependence 3 0.3 0.3 no signal