OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Alteplase

1,032 flagged reaction(s) · 37,872 total co-reports · max PRR 1,255.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Reperfusion Arrhythmia 29 1,255.4 1,257.8 signal
2 Reocclusion 26 720.3 721.6 signal
3 Nih Stroke Scale Score Increased 27 667.9 669.1 signal
4 Nih Stroke Scale Abnormal 10 659.6 660.1 signal
5 Haemorrhagic Transformation Stroke 433 571.3 588.3 signal
6 Cerebral Reperfusion Injury 7 570.4 570.7 signal
7 Postinfarction Angina 12 386.6 386.9 signal
8 Cerebral Hyperperfusion Syndrome 17 318.2 318.6 signal
9 Fibrinolysis Increased 7 293.8 294.0 signal
10 Stroke In Evolution 37 281.6 282.3 signal
11 Haemorrhagic Infarction 76 225.0 226.1 signal
12 Product Closure Issue 63 183.7 184.5 signal
13 Reperfusion Injury 16 183.2 183.4 signal
14 Thrombolysis 25 176.7 177.0 signal
15 Neurological Decompensation 196 132.6 134.4 signal
16 Haemorrhagic Cerebral Infarction 57 123.6 124.0 signal
17 Intercepted Product Storage Error 259 115.4 117.4 signal
18 Gingival Bleeding 1,029 114.3 122.7 signal
19 Tongue Haemorrhage 87 112.1 112.8 signal
20 Fibrinolysis 5 109.9 110.0 signal
21 Blood Fibrinogen Decreased 78 105.1 105.7 signal
22 Cns Ventriculitis 21 96.3 96.5 signal
23 Herpes Simplex Viraemia 7 85.1 85.1 signal
24 Brain Midline Shift 28 77.4 77.6 signal
25 Intercepted Medication Error 244 77.3 78.6 signal
26 Brain Stem Haemorrhage 49 76.1 76.3 signal
27 Haemorrhage Intracranial 737 72.6 76.3 signal
28 Myocardial Rupture 15 71.7 71.7 signal
29 Basilar Artery Occlusion 8 71.5 71.5 signal
30 Cerebral Mass Effect 17 70.3 70.4 signal
31 Rhegmatogenous Retinal Detachment 9 62.6 62.7 signal
32 Extravasation Blood 10 62.4 62.4 signal
33 Vessel Puncture Site Haematoma 8 58.6 58.7 signal
34 Rhythm Idioventricular 13 58.5 58.5 signal
35 Cerebral Haematoma 124 53.9 54.3 signal
36 Accelerated Idioventricular Rhythm 5 53.3 53.3 signal
37 Puncture Site Haemorrhage 25 51.5 51.6 signal
38 Brain Herniation 104 50.6 51.0 signal
39 Parenteral Nutrition 8 50.4 50.4 signal
40 Bullous Haemorrhagic Dermatosis 7 49.5 49.5 signal
41 Vertebral Artery Dissection 7 49.2 49.2 signal
42 Blood Brain Barrier Defect 5 48.4 48.5 signal
43 Basal Ganglia Haemorrhage 26 46.2 46.3 signal
44 Coronary Revascularisation 5 45.0 45.0 signal
45 Lividity 11 43.7 43.7 signal
46 Tongue Haematoma 6 43.5 43.5 signal
47 Restrictive Cardiomyopathy 9 42.6 42.6 signal
48 Aplastic Anaemia 150 41.4 41.8 signal
49 Cerebellar Haematoma 8 40.6 40.6 signal
50 Intraventricular Haemorrhage 69 39.9 40.1 signal
51 Catheter Site Haematoma 8 39.4 39.5 signal
52 Cerebral Artery Occlusion 27 36.4 36.5 signal
53 Artery Dissection 10 34.8 34.8 signal
54 Cerebral Haemorrhage 819 32.9 34.8 signal
55 Retinal Pigment Epithelial Tear 15 31.6 31.7 signal
56 Thrombectomy 7 30.7 30.7 signal
57 Subcutaneous Haematoma 26 29.0 29.1 signal
58 Basal Ganglia Infarction 7 28.9 28.9 signal
59 Hypofibrinogenaemia 19 28.1 28.1 signal
60 Cerebral Artery Thrombosis 10 27.7 27.7 signal
61 Tongue Oedema 73 27.3 27.4 signal
62 Hyphaema 10 27.3 27.3 signal
63 Urogenital Haemorrhage 7 27.2 27.2 signal
64 Mouth Haemorrhage 123 23.9 24.1 signal
65 Macular Hole 22 23.5 23.5 signal
66 Carotid Artery Dissection 7 23.4 23.4 signal
67 Intracranial Haematoma 9 22.8 22.8 signal
68 Haemothorax 46 22.6 22.7 signal
69 Cardiac Ventricular Thrombosis 20 22.6 22.6 signal
70 Treatment Delayed 25 22.0 22.1 signal
71 Cerebral Amyloid Angiopathy 5 22.0 22.0 signal
72 Compartment Syndrome 39 21.3 21.4 signal
73 Brain Compression 6 21.2 21.2 signal
74 Peripheral Embolism 17 20.8 20.8 signal
75 Coagulation Test Abnormal 11 20.6 20.6 signal
76 Vitreous Haemorrhage 40 20.5 20.6 signal
77 Circumoral Oedema 5 20.3 20.3 signal
78 Catheter Site Haemorrhage 35 20.3 20.3 signal
79 No Adverse Event 2,519 20.2 24.1 signal
80 Angioedema 626 20.2 21.0 signal
81 Hemianopia 13 18.5 18.5 signal
82 Retroperitoneal Haemorrhage 32 18.4 18.5 signal
83 Vasogenic Cerebral Oedema 9 18.1 18.1 signal
84 Subarachnoid Haemorrhage 129 18.0 18.1 signal
85 Cerebellar Haemorrhage 18 17.9 17.9 signal
86 Aortic Aneurysm Rupture 12 17.4 17.4 signal
87 Cerebral Artery Embolism 15 17.4 17.4 signal
88 Vascular Pseudoaneurysm 21 17.1 17.1 signal
89 Pericardial Haemorrhage 26 16.9 16.9 signal
90 Haemorrhagic Stroke 93 16.8 16.9 signal
91 Ventricular Extrasystoles 123 16.8 16.9 signal
92 Lip Haemorrhage 15 16.7 16.7 signal
93 Intracranial Mass 11 16.6 16.6 signal
94 Electrocardiogram St Segment Elevation 38 16.3 16.3 signal
95 Cardiac Death 14 16.3 16.3 signal
96 Post Thrombotic Syndrome 5 15.7 15.7 signal
97 Central Nervous System Haemorrhage 5 15.2 15.2 signal
98 Anaphylactoid Shock 5 15.2 15.2 signal
99 Brain Oedema 135 15.2 15.3 signal
100 Embolic Stroke 36 14.6 14.6 signal
101 Thalamus Haemorrhage 9 14.5 14.5 signal
102 Platelet Transfusion 13 14.4 14.4 signal
103 Extravasation 42 14.4 14.4 signal
104 Product Temperature Excursion Issue 48 14.3 14.4 signal
105 Ischaemic Stroke 180 14.3 14.4 signal
106 Incision Site Haemorrhage 8 13.9 13.9 signal
107 Brain Stem Infarction 10 13.8 13.8 signal
108 Alpha Haemolytic Streptococcal Infection 9 13.7 13.7 signal
109 Mucosal Haemorrhage 11 13.5 13.5 signal
110 Interleukin Level Increased 5 13.3 13.3 signal
111 Streptococcal Bacteraemia 10 13.2 13.2 signal
112 Abdominal Wall Haematoma 18 13.1 13.1 signal
113 Cerebral Ischaemia 48 13.1 13.1 signal
114 Renal Vein Thrombosis 6 12.8 12.8 signal
115 Haemorrhage Subcutaneous 32 12.7 12.8 signal
116 Cerebral Infarction 218 12.6 12.8 signal
117 Heart Transplant 8 12.6 12.6 signal
118 Endotracheal Intubation Complication 5 12.1 12.1 signal
119 Vena Cava Thrombosis 14 11.9 11.9 signal
120 Joint Contracture 9 11.9 11.9 signal
121 Ecchymosis 57 11.7 11.8 signal
122 Extradural Haematoma 11 11.7 11.7 signal
123 Retroperitoneal Haematoma 18 11.6 11.6 signal
124 Device Related Thrombosis 8 11.5 11.5 signal
125 Amputation 10 11.3 11.3 signal
126 Hydrocephalus 43 11.2 11.2 signal
127 Ventricular Tachycardia 130 11.1 11.2 signal
128 Peritoneal Haemorrhage 11 11.1 11.1 signal
129 Stridor 23 11.0 11.1 signal
130 Hyperchloraemia 5 11.0 11.1 signal
131 Aneurysm Ruptured 7 10.9 10.9 signal
132 Vasospasm 7 10.8 10.8 signal
133 Haemoperitoneum 6 10.8 10.8 signal
134 Blood Fibrinogen Increased 6 10.6 10.6 signal
135 Embolism Arterial 9 10.6 10.6 signal
136 Electromechanical Dissociation 6 10.5 10.5 signal
137 Cranial Nerve Disorder 5 10.2 10.2 signal
138 Peripheral Artery Occlusion 10 10.1 10.1 signal
139 Intra-abdominal Haemorrhage 17 10.1 10.1 signal
140 Brain Death 22 10.0 10.0 signal
141 Embolism 59 10.0 10.0 signal
142 Carotid Artery Thrombosis 6 9.9 9.9 signal
143 Product Reconstitution Quality Issue 6 9.8 9.8 signal
144 Ventricular Fibrillation 77 9.8 9.8 signal
145 Cerebral Ventricle Dilatation 8 9.8 9.8 signal
146 Heparin-induced Thrombocytopenia 34 9.7 9.7 signal
147 Ischaemic Cerebral Infarction 8 9.7 9.7 signal
148 Apallic Syndrome 5 9.7 9.7 signal
149 Hemianopia Homonymous 5 9.7 9.7 signal
150 Nodal Rhythm 10 9.6 9.6 signal
151 Cardiac Tamponade 32 9.5 9.5 signal
152 Dysphoria 34 9.4 9.5 signal
153 Brain Stem Syndrome 5 9.4 9.4 signal
154 Pulmonary Artery Thrombosis 5 9.1 9.2 signal
155 Endotracheal Intubation 18 9.1 9.1 signal
156 Peripheral Ischaemia 26 9.0 9.0 signal
157 Perforation 5 8.9 8.9 signal
158 Haematoma 163 8.9 8.9 signal
159 Renal Infarct 9 8.7 8.7 signal
160 Subdural Haemorrhage 17 8.7 8.7 signal
161 Blood Creatine Phosphokinase Mb Increased 8 8.7 8.7 signal
162 Hyperphosphataemia 13 8.7 8.7 signal
163 Hemiplegia 51 8.6 8.7 signal
164 Intracardiac Thrombus 19 8.6 8.6 signal
165 Administration Site Extravasation 6 8.6 8.6 signal
166 Pulseless Electrical Activity 25 8.5 8.5 signal
167 Cerebellar Infarction 10 8.4 8.4 signal
168 Splenic Infarction 10 8.1 8.1 signal
169 Cardiogenic Shock 82 8.1 8.2 signal
170 Arterial Thrombosis 11 8.0 8.0 signal
171 Pharyngeal Haemorrhage 7 8.0 8.0 signal
172 Fibrin D Dimer Increased 20 7.9 7.9 signal
173 Empyema 11 7.8 7.8 signal
174 Haemorrhage 574 7.8 8.0 signal
175 Splenic Rupture 9 7.7 7.7 signal
176 Intestinal Infarction 5 7.7 7.7 signal
177 Primary Sequestrum 5 7.7 7.7 signal
178 Catheter Site Swelling 5 7.7 7.7 signal
179 Ischaemia 25 7.6 7.6 signal
180 Intracranial Pressure Increased 30 7.6 7.6 signal
181 Infectious Pleural Effusion 8 7.5 7.5 signal
182 Atrial Thrombosis 11 7.5 7.5 signal
183 Gaze Palsy 9 7.5 7.5 signal
184 Carbon Dioxide Decreased 6 7.4 7.4 signal
185 Hemiparesis 89 7.4 7.4 signal
186 Ventricular Arrhythmia 19 7.3 7.3 signal
187 Carotid Artery Occlusion 19 7.3 7.3 signal
188 Laryngeal Oedema 31 7.1 7.1 signal
189 Aortic Dissection 21 7.1 7.1 signal
190 Vocal Cord Paralysis 9 7.1 7.1 signal
191 Extrasystoles 35 7.0 7.1 signal
192 Blood Loss Anaemia 11 7.0 7.0 signal
193 Consciousness Fluctuating 5 6.9 6.9 signal
194 Hypogonadism 5 6.9 6.9 signal
195 Areflexia 13 6.8 6.8 signal
196 Swollen Tongue 149 6.7 6.8 signal
197 Product Container Issue 40 6.7 6.7 signal
198 Enterococcal Bacteraemia 5 6.7 6.7 signal
199 Lip Oedema 20 6.6 6.7 signal
200 Amyloidosis 8 6.5 6.5 signal
201 Intracranial Venous Sinus Thrombosis 5 6.5 6.5 signal
202 Product Name Confusion 5 6.4 6.4 signal
203 Extremity Necrosis 8 6.4 6.4 signal
204 Thrombosis In Device 15 6.4 6.4 signal
205 Product Storage Error 386 6.3 6.4 signal
206 Haemoglobinuria 5 6.3 6.3 signal
207 Klebsiella Sepsis 5 6.2 6.2 signal
208 Monoparesis 8 6.2 6.2 signal
209 Pupillary Reflex Impaired 8 6.2 6.2 signal
210 Venoocclusive Disease 11 6.2 6.2 signal
211 Procedural Haemorrhage 17 6.1 6.1 signal
212 Ventricular Hypokinesia 14 6.1 6.1 signal
213 Infarction 30 6.1 6.1 signal
214 Activated Partial Thromboplastin Time Prolonged 22 6.1 6.1 signal
215 Aortic Thrombosis 5 6.1 6.1 signal
216 Bradyarrhythmia 7 6.0 6.0 signal
217 Vascular Occlusion 9 6.0 6.0 signal
218 Peripheral Artery Thrombosis 6 6.0 6.0 signal
219 Haematoma Muscle 5 6.0 6.0 signal
220 Pelvic Venous Thrombosis 6 5.9 5.9 signal
221 Bleeding Time Prolonged 5 5.8 5.8 signal
222 Pulmonary Haemorrhage 32 5.8 5.8 signal
223 Pupil Fixed 7 5.7 5.7 signal
224 Aplasia 8 5.6 5.6 signal
225 Blood Urea Decreased 5 5.6 5.6 signal
226 Pleuritic Pain 11 5.6 5.6 signal
227 Cerebrovascular Disorder 12 5.6 5.6 signal
228 Oedema Mouth 13 5.5 5.6 signal
229 Retinal Detachment 36 5.5 5.5 signal
230 Quadriplegia 8 5.5 5.5 signal
231 Blood Pressure Immeasurable 6 5.5 5.5 signal
232 Anticoagulation Drug Level Above Therapeutic 6 5.5 5.5 signal
233 Acute Lymphocytic Leukaemia Recurrent 10 5.5 5.5 signal
234 Haemodynamic Instability 29 5.5 5.5 signal
235 Coagulopathy 64 5.4 5.4 signal
236 Coagulation Time Prolonged 6 5.4 5.4 signal
237 Adenovirus Infection 11 5.4 5.4 signal
238 Livedo Reticularis 8 5.4 5.4 signal
239 Graft Versus Host Disease In Gastrointestinal Tract 8 5.3 5.3 signal
240 Incorrect Product Storage 50 5.3 5.3 signal
241 Ischaemic Hepatitis 5 5.2 5.2 signal
242 Retinal Haemorrhage 26 5.2 5.2 signal
243 Hypercoagulation 7 5.1 5.2 signal
244 Leg Amputation 15 5.1 5.1 signal
245 Atrioventricular Block Second Degree 11 5.1 5.1 signal
246 Quadriparesis 6 5.1 5.1 signal
247 Nephrogenic Systemic Fibrosis 11 5.1 5.1 signal
248 Paresis 8 5.0 5.0 signal
249 N-terminal Prohormone Brain Natriuretic Peptide Increased 5 5.0 5.0 signal
250 Supraventricular Extrasystoles 12 5.0 5.0 signal
251 Haemorrhage Urinary Tract 9 5.0 5.0 signal
252 Injection Site Oedema 6 5.0 5.0 signal
253 Methaemoglobinaemia 8 4.9 4.9 signal
254 Jugular Vein Thrombosis 6 4.8 4.8 signal
255 Neutropenic Colitis 7 4.8 4.8 signal
256 Infusion Site Extravasation 21 4.8 4.8 signal
257 Spinal Cord Compression 13 4.7 4.7 signal
258 Incorrect Drug Administration Rate 14 4.7 4.7 signal
259 Cytokine Release Syndrome 63 4.7 4.7 signal
260 Venous Occlusion 6 4.6 4.6 signal
261 Contraindication To Medical Treatment 5 4.6 4.6 signal
262 Venoocclusive Liver Disease 16 4.6 4.6 signal
263 Product Preparation Error 67 4.6 4.6 signal
264 Anaphylactoid Reaction 13 4.5 4.5 signal
265 Atrioventricular Block Complete 21 4.4 4.4 signal
266 Transfusion 33 4.4 4.4 signal
267 Atelectasis 30 4.4 4.4 signal
268 Product Preparation Issue 18 4.3 4.4 signal
269 Upper Gastrointestinal Haemorrhage 52 4.3 4.3 signal
270 Facial Paralysis 26 4.3 4.3 signal
271 Immune Effector Cell-associated Neurotoxicity Syndrome 17 4.3 4.3 signal
272 Hypernatraemia 15 4.3 4.3 signal
273 Occult Blood Positive 6 4.2 4.2 signal
274 Hypercapnia 9 4.2 4.2 signal
275 Muscle Haemorrhage 12 4.2 4.2 signal
276 Embolism Venous 9 4.2 4.2 signal
277 Coronary Artery Thrombosis 6 4.2 4.2 signal
278 Tachypnoea 40 4.2 4.2 signal
279 Device Occlusion 41 4.1 4.2 signal
280 Acute Respiratory Failure 56 4.1 4.1 signal
281 Sinus Bradycardia 28 4.1 4.1 signal
282 Haematuria 99 4.1 4.1 signal
283 Injection Site Extravasation 36 4.1 4.1 signal
284 Product Contamination 10 4.0 4.0 signal
285 Shock 65 4.0 4.0 signal
286 Shock Haemorrhagic 23 4.0 4.0 signal
287 Neurological Symptom 16 4.0 4.0 signal
288 Mucosal Inflammation 73 3.9 4.0 signal
289 Bradycardia 145 3.8 3.9 signal
290 Pulse Absent 13 3.8 3.8 signal
291 Bacteraemia 32 3.8 3.8 signal
292 Right Ventricular Failure 19 3.8 3.8 signal
293 Sinus Tachycardia 38 3.8 3.8 signal
294 Aphasia 81 3.8 3.8 signal
295 Respiratory Failure 194 3.7 3.8 signal
296 Pneumonia Aspiration 66 3.7 3.7 signal
297 Lip Swelling 88 3.7 3.7 signal
298 Multi-organ Failure 46 3.7 3.7 signal
299 Acute Myocardial Infarction 77 3.7 3.7 signal
300 Haematemesis 66 3.7 3.7 signal
301 Escherichia Bacteraemia 6 3.7 3.7 signal
302 Viith Nerve Paralysis 9 3.6 3.6 signal
303 Staphylococcal Bacteraemia 11 3.6 3.6 signal
304 Hyperaemia 5 3.6 3.6 signal
305 Coma 119 3.5 3.5 signal
306 Failure To Thrive 13 3.5 3.5 signal
307 Angiopathy 14 3.5 3.5 signal
308 Cerebral Thrombosis 7 3.5 3.5 signal
309 Haemoptysis 69 3.5 3.5 signal
310 Vascular Graft 7 3.4 3.4 signal
311 Skin Induration 5 3.4 3.4 signal
312 Protein Total Decreased 9 3.4 3.4 signal
313 Atrial Flutter 19 3.3 3.3 signal
314 Dilatation Ventricular 5 3.3 3.3 signal
315 Arteriosclerosis 22 3.3 3.3 signal
316 Aortic Arteriosclerosis 6 3.3 3.3 signal
317 Central Venous Catheterisation 7 3.3 3.3 signal
318 Prothrombin Time Prolonged 14 3.3 3.3 signal
319 Hypovolaemic Shock 11 3.2 3.3 signal
320 Subdural Haematoma 33 3.2 3.2 signal
321 Hypoxic-ischaemic Encephalopathy 6 3.2 3.2 signal
322 Respiratory Distress 63 3.2 3.2 signal
323 Cerebral Atrophy 9 3.2 3.2 signal
324 Conjunctival Hyperaemia 8 3.2 3.2 signal
325 Hypoxia 77 3.1 3.1 signal
326 Clonus 6 3.1 3.1 signal
327 Hypophosphataemia 16 3.1 3.1 signal
328 Off Label Use 1,868 3.0 3.3 signal
329 Obstructive Airways Disorder 24 3.0 3.0 signal
330 Oxygen Saturation Abnormal 6 3.0 3.0 signal
331 Tumour Haemorrhage 6 3.0 3.0 signal
332 Cardiac Arrest 174 3.0 3.0 signal
333 Conjunctival Haemorrhage 8 2.9 2.9 signal
334 Acidosis 16 2.9 2.9 signal
335 Paraplegia 6 2.9 2.9 signal
336 Rales 12 2.9 2.9 signal
337 Hypovolaemia 12 2.9 2.9 signal
338 Apnoea 16 2.9 2.9 signal
339 Pulmonary Embolism 194 2.9 2.9 signal
340 Tachyarrhythmia 5 2.8 2.8 signal
341 Blood Pressure Systolic Decreased 9 2.8 2.8 signal
342 Hyperparathyroidism Secondary 5 2.8 2.8 signal
343 Haemorrhagic Diathesis 7 2.8 2.8 signal
344 Fibrosis 6 2.7 2.7 signal
345 Intraocular Pressure Increased 25 2.7 2.7 signal
346 Intentional Product Use Issue 171 2.7 2.8 signal
347 Bone Lesion 7 2.7 2.7 signal
348 Blood Phosphorus Decreased 7 2.7 2.7 signal
349 Petechiae 20 2.7 2.7 signal
350 Disseminated Intravascular Coagulation 27 2.7 2.7 signal
351 Circumstance Or Information Capable Of Leading To Medication Error 64 2.7 2.7 signal
352 Serum Ferritin Increased 10 2.7 2.7 signal
353 Radiculopathy 5 2.7 2.7 no signal
354 Dysarthria 71 2.7 2.7 signal
355 Encephalopathy 46 2.6 2.6 signal
356 Loose Tooth 6 2.6 2.6 signal
357 Metastatic Neoplasm 8 2.6 2.6 signal
358 Blood Creatine Phosphokinase Increased 54 2.6 2.6 signal
359 Febrile Neutropenia 122 2.6 2.6 signal
360 Cyanosis 29 2.6 2.6 signal
361 Mental Status Changes 51 2.6 2.6 signal
362 Infective Pulmonary Exacerbation Of Cystic Fibrosis 10 2.6 2.6 signal
363 Anaphylactic Reaction 100 2.6 2.6 signal
364 Medication Error 101 2.6 2.6 signal
365 Device Related Infection 28 2.6 2.6 signal
366 Pneumonia Fungal 7 2.5 2.5 signal
367 Aneurysm 9 2.5 2.5 signal
368 Cardiopulmonary Failure 7 2.5 2.5 signal
369 Gastrointestinal Haemorrhage 150 2.5 2.5 signal
370 No Therapeutic Response 22 2.5 2.5 signal
371 Lung Consolidation 5 2.5 2.5 no signal
372 Venous Thrombosis 7 2.5 2.5 signal
373 Cerebral Disorder 13 2.5 2.5 signal
374 Left Ventricular Failure 6 2.5 2.5 no signal
375 Phlebitis 9 2.5 2.5 signal
376 Haematocrit Decreased 35 2.5 2.5 signal
377 Eye Movement Disorder 12 2.5 2.5 signal
378 Depressed Level Of Consciousness 69 2.5 2.5 signal
379 Myocardial Ischaemia 20 2.5 2.5 signal
380 Septic Shock 75 2.4 2.4 signal
381 Bundle Branch Block Right 8 2.4 2.4 signal
382 Hypotension 346 2.4 2.5 signal
383 Epistaxis 129 2.4 2.4 signal
384 Tumour Lysis Syndrome 15 2.4 2.4 signal
385 Nephrogenic Anaemia 8 2.4 2.4 signal
386 Carotid Artery Stenosis 6 2.4 2.4 no signal
387 Skin Tightness 8 2.4 2.4 signal
388 Peripheral Arterial Occlusive Disease 7 2.4 2.4 signal
389 Lumbar Spinal Stenosis 5 2.4 2.4 no signal
390 Abortion 5 2.4 2.4 no signal
391 Deep Vein Thrombosis 111 2.4 2.4 signal
392 Angina Unstable 11 2.4 2.4 signal
393 Leukocytosis 30 2.3 2.3 signal
394 Congestive Cardiomyopathy 7 2.3 2.3 signal
395 Cardiac Failure Acute 11 2.3 2.3 signal
396 Pericardial Effusion 38 2.3 2.3 signal
397 Gangrene 10 2.3 2.3 signal
398 Intestinal Ischaemia 9 2.3 2.3 signal
399 Purulent Discharge 7 2.3 2.3 no signal
400 Post Procedural Haemorrhage 19 2.3 2.3 signal
401 Brain Natriuretic Peptide Increased 5 2.3 2.3 no signal
402 Portal Hypertension 5 2.3 2.3 no signal
403 Neurotoxicity 28 2.3 2.3 signal
404 Pharyngeal Oedema 25 2.3 2.3 signal
405 Acute Pulmonary Oedema 9 2.3 2.3 signal
406 Anaphylactic Shock 41 2.2 2.3 signal
407 Urine Output Decreased 14 2.2 2.2 signal
408 Unresponsive To Stimuli 41 2.2 2.2 signal
409 Electroencephalogram Abnormal 5 2.2 2.2 no signal
410 Pathological Fracture 8 2.2 2.2 signal
411 Supraventricular Tachycardia 15 2.2 2.2 signal
412 International Normalised Ratio Increased 45 2.2 2.2 signal
413 Infusion Site Haemorrhage 5 2.2 2.2 no signal
414 Pulmonary Hypertension 32 2.2 2.2 signal
415 Injection Site Infection 5 2.1 2.1 no signal
416 Potentiating Drug Interaction 5 2.1 2.1 no signal
417 Haemophagocytic Lymphohistiocytosis 11 2.1 2.1 signal
418 Product Leakage 8 2.1 2.1 no signal
419 Skin Abrasion 7 2.1 2.1 no signal
420 Pulmonary Oedema 67 2.1 2.1 signal
421 Metastases To Spine 5 2.1 2.1 no signal
422 Colitis Ischaemic 10 2.1 2.1 signal
423 Gingivitis 8 2.1 2.1 no signal
424 Aspiration 16 2.1 2.1 signal
425 Decubitus Ulcer 12 2.1 2.1 signal
426 Acute Respiratory Distress Syndrome 26 2.1 2.1 signal
427 Multiple Organ Dysfunction Syndrome 41 2.1 2.1 signal
428 Cerebrovascular Accident 248 2.1 2.1 signal
429 Chest Pain 270 2.0 2.1 signal
430 Oliguria 9 2.0 2.0 no signal
431 Encephalitis 10 2.0 2.0 signal
432 Epstein-barr Virus Infection 9 2.0 2.0 no signal
433 Red Cell Distribution Width Increased 6 2.0 2.0 no signal
434 International Normalised Ratio Abnormal 5 2.0 2.0 no signal
435 Covid-19 Pneumonia 17 2.0 2.0 signal
436 Arrhythmia 68 2.0 2.0 signal
437 Procedural Complication 11 2.0 2.0 signal
438 Mitral Valve Incompetence 16 2.0 2.0 no signal
439 Clostridium Difficile Colitis 15 2.0 2.0 no signal
440 Bronchospasm 20 2.0 2.0 no signal
441 Tricuspid Valve Incompetence 11 2.0 2.0 no signal
442 Pneumothorax 22 2.0 2.0 no signal
443 Hiatus Hernia 18 2.0 2.0 no signal
444 Death 1,192 1.9 2.0 no signal
445 Endocarditis 7 1.9 1.9 no signal
446 Pulmonary Function Test Decreased 6 1.9 1.9 no signal
447 Product Complaint 34 1.9 1.9 no signal
448 Oxygen Saturation Decreased 76 1.9 1.9 no signal
449 Complication Associated With Device 18 1.9 1.9 no signal
450 Cardio-respiratory Arrest 57 1.9 1.9 no signal
451 Meningitis 9 1.9 1.9 no signal
452 Blood Calcium Decreased 15 1.9 1.9 no signal
453 Blood Pressure Decreased 87 1.8 1.8 no signal
454 Skin Laceration 14 1.8 1.8 no signal
455 Localised Oedema 6 1.8 1.8 no signal
456 Anuria 11 1.8 1.8 no signal
457 Arterial Occlusive Disease 10 1.8 1.8 no signal
458 Blood Albumin Decreased 10 1.8 1.8 no signal
459 Spinal Osteoarthritis 11 1.8 1.8 no signal
460 Sepsis 138 1.7 1.7 no signal
461 Lung Infiltration 11 1.7 1.7 no signal
462 Intercepted Product Preparation Error 15 1.7 1.7 no signal
463 International Normalised Ratio Decreased 5 1.7 1.7 no signal
464 Coronary Artery Bypass 7 1.7 1.7 no signal
465 Atrial Fibrillation 118 1.7 1.7 no signal
466 Pallor 33 1.7 1.7 no signal
467 Altered State Of Consciousness 26 1.7 1.7 no signal
468 Hyperpyrexia 5 1.7 1.7 no signal
469 Brain Injury 12 1.7 1.7 no signal
470 Troponin Increased 9 1.7 1.7 no signal
471 Paralysis 17 1.7 1.7 no signal
472 Hypertransaminasaemia 8 1.6 1.7 no signal
473 Injection Site Vesicles 7 1.6 1.6 no signal
474 Hyperbilirubinaemia 12 1.6 1.6 no signal
475 Atrioventricular Block 9 1.6 1.6 no signal
476 Compression Fracture 6 1.6 1.6 no signal
477 Respiratory Arrest 32 1.6 1.6 no signal
478 Status Epilepticus 13 1.6 1.6 no signal
479 Haemoglobin Decreased 117 1.6 1.6 no signal
480 Abdominal Abscess 5 1.6 1.6 no signal
481 Sudden Death 12 1.6 1.6 no signal
482 Gastric Haemorrhage 13 1.6 1.6 no signal
483 Upper-airway Cough Syndrome 9 1.5 1.5 no signal
484 Drug Administration Error 34 1.5 1.5 no signal
485 Malnutrition 12 1.5 1.5 no signal
486 Acute Coronary Syndrome 9 1.5 1.5 no signal
487 Blood Pressure Diastolic Increased 5 1.5 1.5 no signal
488 Blood Urea Increased 18 1.5 1.5 no signal
489 Cardiac Failure 85 1.5 1.5 no signal
490 Pulmonary Congestion 14 1.5 1.5 no signal
491 Generalised Oedema 13 1.5 1.5 no signal
492 Wrong Product Administered 7 1.5 1.5 no signal
493 Pleural Effusion 64 1.5 1.5 no signal
494 Hypervolaemia 5 1.5 1.5 no signal
495 Stress Cardiomyopathy 6 1.5 1.5 no signal
496 Tachycardia 92 1.5 1.5 no signal
497 Drug Interaction 164 1.5 1.5 no signal
498 Respiratory Disorder 31 1.5 1.5 no signal
499 Skin Warm 6 1.4 1.4 no signal
500 Eyelid Oedema 12 1.4 1.4 no signal
501 Blood Pressure Systolic Increased 20 1.4 1.4 no signal
502 Ascites 30 1.4 1.4 no signal
503 Chest Discomfort 104 1.4 1.4 no signal
504 Organising Pneumonia 5 1.4 1.4 no signal
505 Odynophagia 6 1.4 1.4 no signal
506 Breath Sounds Abnormal 5 1.4 1.4 no signal
507 Central Nervous System Lesion 14 1.4 1.4 no signal
508 Staphylococcal Sepsis 5 1.4 1.4 no signal
509 Pancytopenia 56 1.4 1.4 no signal
510 Oedema 54 1.4 1.4 no signal
511 Klebsiella Infection 5 1.4 1.4 no signal
512 Hepatic Failure 30 1.4 1.4 no signal
513 Coronary Artery Stenosis 5 1.4 1.4 no signal
514 Pneumonia Bacterial 9 1.4 1.4 no signal
515 Neutropenic Sepsis 7 1.4 1.4 no signal
516 Partial Seizures 5 1.4 1.4 no signal
517 Graft Versus Host Disease 7 1.4 1.4 no signal
518 Staphylococcal Infection 32 1.4 1.4 no signal
519 Flank Pain 9 1.4 1.4 no signal
520 Nervous System Disorder 30 1.3 1.3 no signal
521 Product Quality Issue 129 1.3 1.3 no signal
522 Electrolyte Imbalance 11 1.3 1.3 no signal
523 Restlessness 35 1.3 1.3 no signal
524 Blood Lactic Acid Increased 5 1.3 1.3 no signal
525 Lower Gastrointestinal Haemorrhage 7 1.3 1.3 no signal
526 Nystagmus 5 1.3 1.3 no signal
527 Thrombosis 76 1.3 1.3 no signal
528 Thrombocytopenia 105 1.3 1.3 no signal
529 Hypokalaemia 43 1.3 1.3 no signal
530 Circulatory Collapse 16 1.3 1.3 no signal
531 Acute Kidney Injury 141 1.3 1.3 no signal
532 Hyperthermia 7 1.3 1.3 no signal
533 Vitamin D Deficiency 9 1.3 1.3 no signal
534 Hepatomegaly 9 1.3 1.3 no signal
535 Haemolysis 7 1.3 1.3 no signal
536 Cardiac Failure Congestive 73 1.3 1.3 no signal
537 Acute Myeloid Leukaemia 14 1.3 1.3 no signal
538 Respiratory Rate Increased 8 1.3 1.3 no signal
539 Small Intestinal Obstruction 11 1.3 1.3 no signal
540 Motor Dysfunction 9 1.2 1.3 no signal
541 Pneumonia 285 1.2 1.2 no signal
542 Poor Quality Product Administered 9 1.2 1.2 no signal
543 Internal Haemorrhage 10 1.2 1.2 no signal
544 Iron Deficiency Anaemia 8 1.2 1.2 no signal
545 Mouth Swelling 5 1.2 1.2 no signal
546 Sensory Loss 7 1.2 1.2 no signal
547 Angina Pectoris 25 1.2 1.2 no signal
548 Seizure 99 1.2 1.2 no signal
549 Tenderness 9 1.2 1.2 no signal
550 Bacterial Infection 16 1.2 1.2 no signal
551 Renal Failure Acute 37 1.2 1.2 no signal
552 Asphyxia 7 1.2 1.2 no signal
553 Peripheral Sensory Neuropathy 5 1.2 1.2 no signal
554 Blood Pressure Increased 131 1.2 1.2 no signal
555 Grand Mal Convulsion 8 1.2 1.2 no signal
556 Lymphocyte Count Decreased 15 1.2 1.2 no signal
557 Hair Disorder 7 1.2 1.2 no signal
558 Hyperhidrosis 108 1.2 1.2 no signal
559 Endophthalmitis 5 1.2 1.2 no signal
560 Osteomyelitis 15 1.2 1.2 no signal
561 Speech Disorder 43 1.2 1.2 no signal
562 Epilepsy 25 1.2 1.2 no signal
563 Dysphagia 77 1.1 1.1 no signal
564 Infusion Site Swelling 5 1.1 1.1 no signal
565 Pain In Jaw 23 1.1 1.1 no signal
566 Cardiomegaly 10 1.1 1.1 no signal
567 Metabolic Acidosis 25 1.1 1.1 no signal
568 Rectal Haemorrhage 34 1.1 1.1 no signal
569 Hypoalbuminaemia 6 1.1 1.1 no signal
570 Aortic Aneurysm 6 1.1 1.1 no signal
571 Post Procedural Complication 15 1.1 1.1 no signal
572 Neutrophil Count Increased 8 1.1 1.1 no signal
573 Wrong Drug Administered 7 1.1 1.1 no signal
574 Hyperglycaemia 28 1.1 1.1 no signal
575 Ejection Fraction Decreased 12 1.1 1.1 no signal
576 Renal Failure Chronic 6 1.1 1.1 no signal
577 Bone Disorder 14 1.1 1.1 no signal
578 Electrocardiogram Abnormal 6 1.1 1.1 no signal
579 Urosepsis 7 1.1 1.1 no signal
580 Anaemia 144 1.1 1.1 no signal
581 Product Packaging Issue 7 1.1 1.1 no signal
582 Blood Lactate Dehydrogenase Increased 12 1.1 1.1 no signal
583 Product Administration Error 15 1.1 1.1 no signal
584 Left Ventricular Dysfunction 5 1.1 1.1 no signal
585 Deformity 7 1.0 1.0 no signal
586 Treatment Failure 61 1.0 1.0 no signal
587 Hiccups 6 1.0 1.0 no signal
588 Generalised Tonic-clonic Seizure 12 1.0 1.0 no signal
589 Hypercholesterolaemia 7 1.0 1.0 no signal
590 Vomiting 342 1.0 1.0 no signal
591 Peripheral Coldness 10 1.0 1.0 no signal
592 Melaena 16 1.0 1.0 no signal
593 Second Primary Malignancy 6 1.0 1.0 no signal
594 Hypomagnesaemia 10 1.0 1.0 no signal
595 Myocardial Infarction 126 1.0 1.0 no signal
596 Sensation Of Foreign Body 6 1.0 1.0 no signal
597 Renal Tubular Necrosis 7 1.0 1.0 no signal
598 Hypophagia 18 1.0 1.0 no signal
599 Pyrexia 244 1.0 1.0 no signal
600 Dermatitis Contact 8 1.0 1.0 no signal
601 Cardiovascular Disorder 18 1.0 1.0 no signal
602 Skin Hyperpigmentation 6 1.0 1.0 no signal
603 Hypotonia 7 1.0 1.0 no signal
604 Lung Infection 11 1.0 1.0 no signal
605 Blood Potassium Decreased 21 1.0 1.0 no signal
606 Lethargy 40 1.0 1.0 no signal
607 Dermatitis Bullous 5 1.0 1.0 no signal
608 Respiratory Syncytial Virus Infection 6 1.0 1.0 no signal
609 Skin Haemorrhage 10 1.0 1.0 no signal
610 Pregnancy 14 1.0 1.0 no signal
611 Abscess 11 1.0 1.0 no signal
612 Psychological Trauma 6 1.0 1.0 no signal
613 Bone Marrow Failure 14 1.0 1.0 no signal
614 Blood Alkaline Phosphatase Increased 17 1.0 1.0 no signal
615 Madarosis 8 1.0 1.0 no signal
616 Oral Disorder 5 1.0 1.0 no signal
617 Purpura 6 1.0 1.0 no signal
618 Fluid Overload 10 1.0 1.0 no signal
619 Cytopenia 8 0.9 0.9 no signal
620 Oral Pain 15 0.9 0.9 no signal
621 Haemolytic Anaemia 6 0.9 0.9 no signal
622 Face Oedema 11 0.9 0.9 no signal
623 Bronchopulmonary Aspergillosis 5 0.9 0.9 no signal
624 Dyspnoea Exertional 24 0.9 0.9 no signal
625 Colitis 24 0.9 0.9 no signal
626 Hair Colour Changes 8 0.9 0.9 no signal
627 General Physical Health Deterioration 73 0.9 0.9 no signal
628 Myasthenia Gravis 5 0.9 0.9 no signal
629 Vaginal Haemorrhage 27 0.9 0.9 no signal
630 Furuncle 5 0.9 0.9 no signal
631 Nephropathy Toxic 7 0.9 0.9 no signal
632 Hypertensive Crisis 7 0.9 0.9 no signal
633 Mydriasis 8 0.9 0.9 no signal
634 Hypertension 132 0.9 0.9 no signal
635 Local Swelling 11 0.9 0.9 no signal
636 Platelet Count Decreased 66 0.9 0.9 no signal
637 Polyuria 5 0.9 0.9 no signal
638 Dyspnoea 345 0.9 0.9 no signal
639 Pulmonary Mass 9 0.9 0.8 no signal
640 Infusion Site Erythema 5 0.8 0.8 no signal
641 Pericarditis 10 0.8 0.8 no signal
642 White Blood Cell Count Increased 23 0.8 0.8 no signal
643 End Stage Renal Disease 11 0.8 0.8 no signal
644 Stomatitis 36 0.8 0.8 no signal
645 Blood Bilirubin Increased 16 0.8 0.8 no signal
646 Transient Ischaemic Attack 20 0.8 0.8 no signal
647 Haemodialysis 5 0.8 0.8 no signal
648 Polyneuropathy 7 0.8 0.8 no signal
649 Inappropriate Schedule Of Product Administration 104 0.8 0.8 no signal
650 Temperature Intolerance 6 0.8 0.8 no signal
651 Ataxia 7 0.8 0.8 no signal
652 Tooth Abscess 6 0.8 0.8 no signal
653 Convulsion 34 0.8 0.8 no signal
654 Drug Effect Decreased 32 0.8 0.8 no signal
655 Hyperlipidaemia 7 0.8 0.8 no signal
656 Hypersensitivity 108 0.8 0.8 no signal
657 Hypocalcaemia 11 0.8 0.8 no signal
658 Poor Venous Access 6 0.8 0.8 no signal
659 Blood Creatinine Increased 38 0.8 0.8 no signal
660 Coronary Artery Occlusion 8 0.8 0.8 no signal
661 Peritonitis 12 0.8 0.8 no signal
662 Presyncope 14 0.8 0.8 no signal
663 Delirium 20 0.8 0.8 no signal
664 Immunosuppression 5 0.8 0.8 no signal
665 Cardiac Murmur 5 0.8 0.8 no signal
666 Glaucoma 11 0.8 0.8 no signal
667 Respiratory Depression 7 0.8 0.8 no signal
668 Hypercalcaemia 7 0.8 0.8 no signal
669 Cold Sweat 10 0.8 0.8 no signal
670 Contraindicated Product Administered 17 0.8 0.8 no signal
671 Muscular Weakness 64 0.8 0.8 no signal
672 Haemorrhoids 11 0.8 0.8 no signal
673 Device Issue 49 0.8 0.8 no signal
674 Renal Failure 75 0.8 0.8 no signal
675 Neuropathy Peripheral 53 0.8 0.8 no signal
676 Labelled Drug-drug Interaction Medication Error 5 0.8 0.8 no signal
677 Red Blood Cell Count Decreased 16 0.8 0.8 no signal
678 Clostridium Difficile Infection 12 0.8 0.8 no signal
679 Gastroenteritis 8 0.8 0.8 no signal
680 Injection Site Haematoma 8 0.8 0.8 no signal
681 Confusional State 87 0.8 0.8 no signal
682 Body Temperature Increased 11 0.8 0.8 no signal
683 Intervertebral Disc Degeneration 5 0.8 0.8 no signal
684 Platelet Count Increased 7 0.8 0.8 no signal
685 Rash Papular 12 0.8 0.8 no signal
686 Oedema Peripheral 65 0.7 0.7 no signal
687 Infusion Related Reaction 35 0.7 0.7 no signal
688 Sputum Discoloured 5 0.7 0.7 no signal
689 Chills 62 0.7 0.7 no signal
690 Osteopenia 8 0.7 0.7 no signal
691 Muscle Twitching 12 0.7 0.7 no signal
692 Hair Texture Abnormal 7 0.7 0.7 no signal
693 Neutrophil Count Decreased 21 0.7 0.7 no signal
694 Hepatic Function Abnormal 19 0.7 0.7 no signal
695 Device Malfunction 34 0.7 0.7 no signal
696 Myoclonus 6 0.7 0.7 no signal
697 Adrenal Insufficiency 6 0.7 0.7 no signal
698 Lactic Acidosis 16 0.7 0.7 no signal
699 Blindness Unilateral 7 0.7 0.7 no signal
700 Ileus 6 0.7 0.7 no signal
701 Hyperkalaemia 17 0.7 0.7 no signal
702 Drug Ineffective 635 0.7 0.7 no signal
703 Heart Rate Decreased 17 0.7 0.7 no signal
704 Osteonecrosis Of Jaw 12 0.7 0.7 no signal
705 Pulmonary Arterial Hypertension 7 0.7 0.7 no signal
706 Muscle Atrophy 6 0.7 0.7 no signal
707 Upper Respiratory Tract Infection 22 0.7 0.7 no signal
708 Agitation 35 0.7 0.7 no signal
709 Gastric Ulcer 9 0.7 0.7 no signal
710 Urinary Incontinence 14 0.7 0.7 no signal
711 Retching 10 0.7 0.7 no signal
712 Nausea 369 0.7 0.6 no signal
713 Scar 8 0.7 0.7 no signal
714 Musculoskeletal Discomfort 8 0.7 0.7 no signal
715 Therapy Partial Responder 7 0.7 0.7 no signal
716 Urticaria 77 0.6 0.6 no signal
717 Respiratory Tract Infection 12 0.6 0.6 no signal
718 Flushing 47 0.6 0.6 no signal
719 Product Dispensing Error 10 0.6 0.6 no signal
720 Mental Disorder 20 0.6 0.6 no signal
721 Gastritis 12 0.6 0.6 no signal
722 Disability 9 0.6 0.6 no signal
723 Neuralgia 11 0.6 0.6 no signal
724 Anhedonia 12 0.6 0.6 no signal
725 Musculoskeletal Chest Pain 7 0.6 0.6 no signal
726 Blood Triglycerides Increased 8 0.6 0.6 no signal
727 Joint Range Of Motion Decreased 6 0.6 0.6 no signal
728 Pneumonitis 12 0.6 0.6 no signal
729 Ulcer 7 0.6 0.6 no signal
730 Brain Neoplasm 4 0.6 0.6 no signal
731 Dysuria 16 0.6 0.6 no signal
732 Aspartate Aminotransferase Increased 23 0.6 0.6 no signal
733 Swelling Face 28 0.6 0.6 no signal
734 Abdominal Pain 99 0.6 0.6 no signal
735 Heart Rate Increased 42 0.6 0.6 no signal
736 Infection 61 0.6 0.6 no signal
737 Wheezing 25 0.6 0.6 no signal
738 Hepatocellular Injury 6 0.6 0.6 no signal
739 Cholecystitis 5 0.6 0.6 no signal
740 Urinary Retention 14 0.6 0.6 no signal
741 Limb Discomfort 13 0.6 0.6 no signal
742 Renal Impairment 35 0.6 0.6 no signal
743 Sleep Apnoea Syndrome 8 0.6 0.6 no signal
744 Musculoskeletal Disorder 8 0.6 0.6 no signal
745 Pharyngeal Swelling 4 0.6 0.6 no signal
746 Impaired Quality Of Life 6 0.6 0.6 no signal
747 Therapy Change 4 0.6 0.6 no signal
748 Loss Of Consciousness 53 0.6 0.6 no signal
749 Neutropenia 56 0.6 0.6 no signal
750 Thrombotic Microangiopathy 4 0.6 0.6 no signal
751 Osteoporosis 17 0.6 0.6 no signal
752 Headache 258 0.6 0.6 no signal
753 Disease Progression 48 0.6 0.6 no signal
754 Cardiomyopathy 6 0.6 0.6 no signal
755 Sinus Disorder 8 0.6 0.6 no signal
756 Chronic Obstructive Pulmonary Disease 21 0.6 0.6 no signal
757 Dermatitis Allergic 5 0.6 0.6 no signal
758 Hypoaesthesia Oral 6 0.6 0.6 no signal
759 Peritonitis Bacterial 4 0.6 0.6 no signal
760 Device Failure 6 0.6 0.6 no signal
761 Hypothermia 4 0.6 0.6 no signal
762 Coronary Artery Disease 12 0.6 0.6 no signal
763 Infusion Site Pain 5 0.5 0.5 no signal
764 Alanine Aminotransferase Increased 24 0.5 0.5 no signal
765 Metastases To Central Nervous System 5 0.5 0.5 no signal
766 C-reactive Protein Increased 14 0.5 0.5 no signal
767 Palmar-plantar Erythrodysaesthesia Syndrome 9 0.5 0.5 no signal
768 Restless Legs Syndrome 7 0.5 0.5 no signal
769 Conjunctivitis 7 0.5 0.5 no signal
770 Hereditary Angioedema 4 0.5 0.5 no signal
771 Productive Cough 18 0.5 0.5 no signal
772 Osteoarthritis 16 0.5 0.5 no signal
773 Dysphonia 22 0.5 0.5 no signal
774 Obesity 6 0.5 0.5 no signal
775 Contusion 36 0.5 0.5 no signal
776 Sars-cov-2 Test Positive 5 0.5 0.5 no signal
777 Cough 104 0.5 0.5 no signal
778 Muscle Tightness 6 0.5 0.5 no signal
779 Throat Tightness 10 0.5 0.5 no signal
780 Metastases To Bone 6 0.5 0.5 no signal
781 Pulmonary Fibrosis 7 0.5 0.5 no signal
782 Pulmonary Thrombosis 4 0.5 0.5 no signal
783 Chronic Kidney Disease 28 0.5 0.5 no signal
784 Discomfort 22 0.5 0.5 no signal
785 Asthenia 136 0.5 0.5 no signal
786 Rash Maculo-papular 8 0.5 0.5 no signal
787 Candida Infection 6 0.5 0.5 no signal
788 Oral Discomfort 5 0.5 0.5 no signal
789 Therapy Non-responder 16 0.5 0.5 no signal
790 Feeling Cold 10 0.5 0.5 no signal
791 Incorrect Route Of Product Administration 6 0.5 0.5 no signal
792 Intestinal Perforation 4 0.5 0.5 no signal
793 Hyponatraemia 20 0.5 0.5 no signal
794 Fistula 4 0.5 0.5 no signal
795 Myocarditis 4 0.5 0.5 no signal
796 Back Pain 82 0.5 0.5 no signal
797 Neoplasm 4 0.5 0.5 no signal
798 Hypoaesthesia 52 0.5 0.5 no signal
799 Metastases To Lung 4 0.5 0.5 no signal
800 Neoplasm Malignant 23 0.5 0.5 no signal
801 Pain 212 0.5 0.5 no signal
802 Metastases To Liver 6 0.5 0.5 no signal
803 Liver Function Test Abnormal 10 0.5 0.5 no signal
804 Movement Disorder 11 0.5 0.5 no signal
805 Maternal Exposure During Pregnancy 30 0.5 0.5 no signal
806 Immunodeficiency 5 0.5 0.5 no signal
807 Cellulitis 17 0.5 0.5 no signal
808 Abdominal Distension 35 0.5 0.5 no signal
809 Tooth Loss 7 0.5 0.5 no signal
810 Impaired Healing 11 0.5 0.5 no signal
811 Electrocardiogram Qt Prolonged 12 0.5 0.5 no signal
812 Ill-defined Disorder 20 0.5 0.5 no signal
813 Skin Discolouration 15 0.5 0.5 no signal
814 Injury 23 0.5 0.5 no signal
815 Increased Tendency To Bruise 3 0.5 0.5 no signal
816 Economic Problem 5 0.5 0.5 no signal
817 Device Dislocation 14 0.5 0.5 no signal
818 Musculoskeletal Pain 17 0.5 0.5 no signal
819 Diarrhoea Haemorrhagic 3 0.4 0.4 no signal
820 Blood Sodium Decreased 6 0.4 0.4 no signal
821 Condition Aggravated 96 0.4 0.4 no signal
822 Skin Fissures 6 0.4 0.4 no signal
823 Urinary Tract Infection 54 0.4 0.4 no signal
824 Fracture 6 0.4 0.4 no signal
825 Posterior Reversible Encephalopathy Syndrome 3 0.4 0.4 no signal
826 Blood Urine Present 6 0.4 0.4 no signal
827 Dehydration 42 0.4 0.4 no signal
828 Sensory Disturbance 5 0.4 0.4 no signal
829 Device Defective 5 0.4 0.4 no signal
830 Somnolence 62 0.4 0.4 no signal
831 Blood Potassium Increased 5 0.4 0.4 no signal
832 Device Leakage 13 0.4 0.4 no signal
833 Erythema 63 0.4 0.4 no signal
834 Deafness 8 0.4 0.4 no signal
835 Joint Stiffness 8 0.4 0.4 no signal
836 Blood Pressure Abnormal 6 0.4 0.4 no signal
837 Pancreatitis 16 0.4 0.4 no signal
838 Disorientation 12 0.4 0.4 no signal
839 Expired Product Administered 10 0.4 0.4 no signal
840 Feeding Disorder 6 0.4 0.4 no signal
841 Skin Disorder 10 0.4 0.4 no signal
842 Swelling 28 0.4 0.4 no signal
843 Rash Erythematous 14 0.4 0.4 no signal
844 Therapeutic Response Decreased 18 0.4 0.4 no signal
845 Ovarian Cyst 3 0.4 0.4 no signal
846 Anxiety 85 0.4 0.4 no signal
847 White Blood Cell Count Decreased 32 0.4 0.4 no signal
848 Inappropriate Antidiuretic Hormone Secretion 3 0.4 0.4 no signal
849 Acute Hepatic Failure 4 0.4 0.4 no signal
850 Scratch 3 0.4 0.4 no signal
851 Liver Injury 7 0.4 0.4 no signal
852 Product Use Issue 54 0.4 0.4 no signal
853 Eosinophilia 5 0.4 0.4 no signal
854 Neck Pain 16 0.4 0.4 no signal
855 Covid-19 50 0.4 0.4 no signal
856 Constipation 61 0.4 0.4 no signal
857 Cystitis 9 0.4 0.4 no signal
858 Plasma Cell Myeloma 11 0.4 0.4 no signal
859 Hip Fracture 9 0.4 0.4 no signal
860 Paraesthesia 44 0.4 0.4 no signal
861 Feeling Hot 17 0.4 0.4 no signal
862 Incorrect Route Of Drug Administration 10 0.4 0.4 no signal
863 Product Packaging Quantity Issue 3 0.4 0.4 no signal
864 Rash 119 0.4 0.4 no signal
865 Osteonecrosis 9 0.4 0.4 no signal
866 Laboratory Test Abnormal 8 0.4 0.4 no signal
867 Skin Ulcer 7 0.4 0.4 no signal
868 Agranulocytosis 5 0.4 0.4 no signal
869 Blindness 11 0.4 0.4 no signal
870 Transaminases Increased 6 0.4 0.4 no signal
871 Diplopia 7 0.4 0.4 no signal
872 Stevens-johnson Syndrome 6 0.4 0.4 no signal
873 Visual Acuity Reduced 9 0.4 0.4 no signal
874 Glossodynia 6 0.4 0.4 no signal
875 Pain In Extremity 79 0.4 0.4 no signal
876 Hepatic Cirrhosis 5 0.4 0.4 no signal
877 Renal Injury 8 0.4 0.4 no signal
878 Lung Disorder 13 0.4 0.4 no signal
879 Impaired Driving Ability 3 0.4 0.4 no signal
880 Bone Loss 4 0.4 0.4 no signal
881 Oropharyngeal Pain 24 0.4 0.4 no signal
882 Rash Macular 9 0.4 0.4 no signal
883 Skin Lesion 7 0.4 0.4 no signal
884 Renal Disorder 12 0.4 0.4 no signal
885 Cardiac Disorder 24 0.4 0.4 no signal
886 Bronchitis 19 0.4 0.4 no signal
887 Emotional Distress 31 0.4 0.4 no signal
888 Haematochezia 14 0.4 0.4 no signal
889 Head Injury 8 0.4 0.4 no signal
890 Drug Hypersensitivity 49 0.4 0.4 no signal
891 Disease Recurrence 12 0.4 0.4 no signal
892 Blister 14 0.4 0.4 no signal
893 Gastrooesophageal Reflux Disease 20 0.4 0.3 no signal
894 Blood Pressure Fluctuation 6 0.4 0.3 no signal
895 Peripheral Swelling 38 0.3 0.3 no signal
896 Mental Impairment 6 0.3 0.3 no signal
897 Malignant Neoplasm Progression 25 0.3 0.3 no signal
898 Dizziness 122 0.3 0.3 no signal
899 Pruritus 92 0.3 0.3 no signal
900 Intestinal Obstruction 9 0.3 0.3 no signal
901 Overdose 52 0.3 0.3 no signal
902 Amenorrhoea 4 0.3 0.3 no signal
903 Mobility Decreased 17 0.3 0.3 no signal
904 Cognitive Disorder 11 0.3 0.3 no signal
905 Liver Function Test Increased 5 0.3 0.3 no signal
906 Decreased Appetite 54 0.3 0.3 no signal
907 Drug Exposure During Pregnancy 8 0.3 0.3 no signal
908 Pruritus Generalised 5 0.3 0.3 no signal
909 Lymphadenopathy 8 0.3 0.3 no signal
910 Emotional Disorder 7 0.3 0.3 no signal
911 Dyspepsia 22 0.3 0.3 no signal
912 Sinusitis 23 0.3 0.3 no signal
913 Chromaturia 5 0.3 0.3 no signal
914 Hypothyroidism 7 0.3 0.3 no signal
915 Cataract 13 0.3 0.3 no signal
916 Diverticulitis 6 0.3 0.3 no signal
917 Wound 6 0.3 0.3 no signal
918 Fatigue 167 0.3 0.3 no signal
919 Hallucination 16 0.3 0.3 no signal
920 Viral Infection 7 0.3 0.3 no signal
921 Syncope 21 0.3 0.3 no signal
922 Hypoglycaemia 10 0.3 0.3 no signal
923 Liver Disorder 9 0.3 0.3 no signal
924 Psychotic Disorder 6 0.3 0.3 no signal
925 Wrong Technique In Product Usage Process 41 0.3 0.3 no signal
926 Rhinorrhoea 13 0.3 0.3 no signal
927 Accidental Exposure To Product 20 0.3 0.3 no signal
928 Incorrect Dose Administered 45 0.3 0.3 no signal
929 Burning Sensation 14 0.3 0.3 no signal
930 Diarrhoea 128 0.3 0.3 no signal
931 Incorrect Product Administration Duration 4 0.3 0.3 no signal
932 Wrong Technique In Device Usage Process 9 0.3 0.3 no signal
933 Nephrolithiasis 9 0.3 0.3 no signal
934 Blood Count Abnormal 3 0.3 0.3 no signal
935 Visual Impairment 24 0.3 0.3 no signal
936 Femur Fracture 6 0.3 0.3 no signal
937 Alopecia 38 0.3 0.3 no signal
938 Vision Blurred 26 0.3 0.3 no signal
939 Weight Decreased 53 0.3 0.3 no signal
940 Palpitations 22 0.3 0.3 no signal
941 Night Sweats 6 0.3 0.3 no signal
942 Unevaluable Event 14 0.3 0.3 no signal
943 Fear 5 0.3 0.3 no signal
944 Cholelithiasis 6 0.3 0.3 no signal
945 Dementia 5 0.3 0.3 no signal
946 Aggression 9 0.3 0.3 no signal
947 Underdose 13 0.2 0.2 no signal
948 Gait Disturbance 34 0.2 0.2 no signal
949 Dyskinesia 7 0.2 0.2 no signal
950 Neoplasm Progression 6 0.2 0.2 no signal
951 Bone Pain 10 0.2 0.2 no signal
952 Therapeutic Product Effect Incomplete 12 0.2 0.2 no signal
953 Gastrointestinal Disorder 15 0.2 0.2 no signal
954 Arthralgia 70 0.2 0.2 no signal
955 Fall 56 0.2 0.2 no signal
956 Tremor 27 0.2 0.2 no signal
957 Eye Swelling 6 0.2 0.2 no signal
958 Leukopenia 8 0.2 0.2 no signal
959 Muscle Spasms 29 0.2 0.2 no signal
960 Nasal Congestion 9 0.2 0.2 no signal
961 Amnesia 10 0.2 0.2 no signal
962 Dry Skin 20 0.2 0.2 no signal
963 Product Use In Unapproved Indication 37 0.2 0.2 no signal
964 Gait Inability 5 0.2 0.2 no signal
965 Menorrhagia 3 0.2 0.2 no signal
966 Extra Dose Administered 6 0.2 0.2 no signal
967 Disturbance In Attention 8 0.2 0.2 no signal
968 Insomnia 39 0.2 0.2 no signal
969 Rhabdomyolysis 6 0.2 0.2 no signal
970 Drug Ineffective For Unapproved Indication 8 0.2 0.2 no signal
971 Completed Suicide 12 0.2 0.2 no signal
972 Systemic Lupus Erythematosus 5 0.2 0.2 no signal
973 Incorrect Drug Administration Duration 4 0.2 0.2 no signal
974 Depression 32 0.2 0.2 no signal
975 Hypoacusis 6 0.2 0.2 no signal
976 Arthritis 11 0.2 0.2 no signal
977 Illness 14 0.2 0.2 no signal
978 Malaise 61 0.2 0.2 no signal
979 Injection Site Haemorrhage 11 0.2 0.2 no signal
980 Fluid Retention 7 0.2 0.2 no signal
981 Blood Glucose Increased 26 0.2 0.2 no signal
982 Migraine 13 0.2 0.2 no signal
983 Inflammation 7 0.2 0.2 no signal
984 Abdominal Pain Upper 27 0.2 0.2 no signal
985 Exposure During Pregnancy 8 0.2 0.2 no signal
986 Eye Pain 7 0.2 0.2 no signal
987 Abnormal Behaviour 5 0.2 0.2 no signal
988 Hospitalisation 19 0.2 0.2 no signal
989 Lung Neoplasm Malignant 5 0.2 0.2 no signal
990 Surgery 7 0.2 0.2 no signal
991 Hepatic Enzyme Increased 8 0.2 0.2 no signal
992 Gastric Cancer 3 0.2 0.2 no signal
993 Weight Increased 26 0.2 0.2 no signal
994 Memory Impairment 16 0.2 0.2 no signal
995 Drug Intolerance 11 0.2 0.2 no signal
996 Pharmaceutical Product Complaint 3 0.2 0.2 no signal
997 Rash Pruritic 6 0.2 0.2 no signal
998 Lower Respiratory Tract Infection 5 0.2 0.2 no signal
999 Ocular Hyperaemia 5 0.2 0.1 no signal
1000 Myalgia 18 0.1 0.1 no signal
1001 Loss Of Personal Independence In Daily Activities 5 0.1 0.1 no signal
1002 Diabetes Mellitus 8 0.1 0.1 no signal
1003 Herpes Zoster 6 0.1 0.1 no signal
1004 Balance Disorder 9 0.1 0.1 no signal
1005 Intentional Product Misuse 9 0.1 0.1 no signal
1006 Interstitial Lung Disease 5 0.1 0.1 no signal
1007 Pancreatic Carcinoma 3 0.1 0.1 no signal
1008 Irritability 6 0.1 0.1 no signal
1009 Product Dose Omission Issue 28 0.1 0.1 no signal
1010 Therapy Cessation 5 0.1 0.1 no signal
1011 Hot Flush 7 0.1 0.1 no signal
1012 Nasopharyngitis 17 0.1 0.1 no signal
1013 Asthma 10 0.1 0.1 no signal
1014 Therapy Interrupted 6 0.1 0.1 no signal
1015 Skin Exfoliation 7 0.1 0.1 no signal
1016 Feeling Abnormal 19 0.1 0.1 no signal
1017 Abdominal Discomfort 13 0.1 0.1 no signal
1018 Device Breakage 3 0.1 0.1 no signal
1019 Product Dose Omission 5 0.1 0.1 no signal
1020 Joint Swelling 9 0.1 0.1 no signal
1021 Influenza 8 0.1 0.1 no signal
1022 Sleep Disorder 5 0.1 0.1 no signal
1023 Musculoskeletal Stiffness 6 0.1 0.1 no signal
1024 Adverse Drug Reaction 6 0.1 0.1 no signal
1025 Injection Site Erythema 8 0.1 0.1 no signal
1026 Renal Cancer 3 0.1 0.1 no signal
1027 Dry Mouth 5 0.1 0.1 no signal
1028 Foetal Exposure During Pregnancy 5 0.1 0.1 no signal
1029 Influenza Like Illness 5 0.1 0.1 no signal
1030 Breast Cancer 5 0.1 0.1 no signal
1031 Toxicity To Various Agents 8 0.1 0.1 no signal
1032 Injection Site Pain 13 0.1 0.1 no signal