Reaction

Brain Herniation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,949 reports · 134 co-occurring drugs

As of the last recalculation, Brain Herniation appears in 2,949 FAERS reports alongside 134 co-occurring drug terms. The strongest observed disproportionality signal is ALTEPLASE (PRR 50.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alteplase	104	50.6	51.0
Ganciclovir	40	28.0	28.1
Ganciclovir Sodium	41	27.7	27.8
Nevirapine	33	26.1	26.2
Fondaparinux Sodium	29	25.5	25.6
Amphotericin B	44	25.1	25.2
Cefazolin	32	25.0	25.1
Cefazolin Sodium	41	24.3	24.4
Phenytoin	70	24.2	24.3
Efavirenz	37	23.7	23.8
Cefepime	45	22.5	22.6
Cefepime Hydrochloride	47	20.9	21.0
Valganciclovir Hydrochloride Powder,	33	19.3	19.4
Posaconazole Delayed-Release	29	18.8	18.9
Voriconazole Injection	53	17.5	17.6
Heparin Sodium	33	17.1	17.2
Micafungin Sodium	19	15.9	15.9
Lopinavir And Ritonavir	28	14.7	14.7
Acetylcysteine	19	14.3	14.3
Valganciclovir	37	14.0	14.0
Valganciclovir Hydrochloride	37	14.0	14.0
Propofol	69	13.6	13.6
Posaconazole	31	13.6	13.6
Meropenem	58	13.0	13.0
Voriconazole	54	12.8	12.8
Norepinephrine	19	12.6	12.6
Norepinephrine Bitartrate	25	12.4	12.4
Pegaspargase	20	11.6	11.6
Basiliximab	19	11.5	11.5
Sevoflurane	13	11.1	11.1
Midazolam	39	11.1	11.1
Ceftriaxone	50	10.9	10.9
Midazolam Hydrochloride	41	10.9	10.9
Axicabtagene Ciloleucel	15	10.8	10.8
Cytarabine	87	10.5	10.5
Ceftriaxone Sodium	55	10.3	10.3
Methadone Hydrochloride	15	9.8	9.8
Clopidogrel Bisulfate	129	9.3	9.3
Busulfan	20	9.0	9.0
Mycophenilic Acid	26	8.9	8.9
Vincristine Sulfate	36	8.8	8.8
Vancomycin	70	8.7	8.7
Dalteparin Sodium	13	8.7	8.7
Ticagrelor	36	8.1	8.1
Vancomycin Hydrochloride	73	8.0	8.0
Derma Foam Excel Hand Sanitizer	9	8.0	8.0
Ethanol	9	7.9	7.9
Gentamicin	14	7.6	7.6
Pyrazinamide	10	7.5	7.5
Quetiapine Fumarate	31	7.5	7.5
Tacrolimus Ointment 0.1%	127	7.5	7.5
Tacrolimus Extended-Release Capsules	127	7.5	7.5
Fludarabine Phosphate	41	7.4	7.5
Cladribine	10	7.4	7.4
Gentamicin Sulfate	16	7.2	7.2
Warfarin Sodium	46	7.1	7.1
Tacrolimus	148	7.0	7.0
Warfarin	120	6.9	6.9
Atropine	8	6.8	6.8
Blinatumomab	10	6.8	6.8
Piperacillin And Tazobactam	12	6.6	6.6
Sodium Bicarbonate	21	6.4	6.4
Sodium Bicarbonate Injection,	21	6.4	6.4
Enoxaparin Sodium	50	6.2	6.2
Piperacillin Sodium,Tazobactam Sodium	23	6.2	6.2
Piperacillin Sodium And Tazobactam Sodium	17	6.1	6.2
Valproic Acid	27	6.1	6.1
Rocuronium Bromide	10	6.0	6.0
Amphetamine	7	6.0	6.0
Linezolid	25	6.0	6.0
Atropine Sulfate	9	5.9	5.9
Levetiracetam In Sodium Chloride	63	5.8	5.8
Levetiracetam Oral	63	5.8	5.8
Levetiracetam Injection	63	5.8	5.8
Mycophenolic Acid	26	5.8	5.8
Temozolomide	17	5.7	5.7
Diphenhydramine Hcl	9	5.7	5.7
Lidicaine	39	5.7	5.7
Burn Relief	39	5.7	5.7
Lidocaine Hydrochloride And Epinephrine	39	5.7	5.7
Mycophenolate Mofetil	105	5.6	5.6
Mycophenolate Mofetil Hydrochloride	105	5.6	5.6
Lidocaine, Menthol	39	5.6	5.6
Prasugrel Hydrochloride	8	5.6	5.6
Tranexamic Acid	7	5.6	5.6
Methadone	33	5.5	5.5
Epoprostenol	10	5.4	5.4
Zidovudine	10	5.3	5.3
Ifosfamide	16	5.3	5.3
Apixaban	48	5.1	5.1
Extended Phenytoin Sodium	12	5.1	5.1
Levetiracetam	93	5.0	5.0
Dabigatran Etexilate Mesylate	50	4.9	4.9
Tenofovir Disoproxil Fumarate Tablets	6	4.9	4.9
Dabigatran Etexilate	53	4.9	4.9
Clopidogrel	131	4.8	4.8
Isoniazid	11	4.8	4.8
Sodium Chloride	52	4.7	4.7
Hydroxyurea	14	4.7	4.7
Etoposide	48	4.7	4.7
Alcohol	25	4.6	4.6
Sodium Chloride Tablet	47	4.6	4.6
Sodium Chloride Tablets	47	4.6	4.6
Bupivacaine	6	4.5	4.5
Loperamide Hcl	8	4.4	4.4
Dextrose	8	4.3	4.3
Fentanyl	59	4.3	4.3
Oxazepam	13	4.3	4.3
Thalidomide	22	4.3	4.3
Dextrose Monohydrate	8	4.2	4.2
Cyclophosphamide Injection, Solution	103	4.2	4.2
Cyclophosphamide	103	4.2	4.2
Cyclophosphamide For Injection	103	4.2	4.2
Lamivudine Oral	15	4.2	4.2
Ethyl Alcohol	16	4.2	4.2
Pitavastatin Calcium	6	4.1	4.1
Rivaroxaban	115	4.0	4.0
Isopropyl Alcohol	18	3.8	3.8
Dexamethasone 1.5 Mg	146	3.6	3.6
Nilotinib	15	3.6	3.6
Dexamethasone	146	3.6	3.6
Ixazomib	14	3.4	3.4
Fentanyl Citrate	8	3.2	3.2
Eltrombopag Olamine	10	3.1	3.1
Agalsidase Beta	4	3.1	3.1
Thiotepa	4	3.0	3.0
Doxorubicin	36	2.9	2.9
Remdesivir	5	2.7	2.7
Eculizumab	19	2.5	2.5
Ruxolitinib	25	2.5	2.5
Brivaracetam	3	2.4	2.4
Gefitinib	3	2.3	2.3
Romiplostim	5	2.3	2.3
Daptomycin	3	2.3	2.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.