OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Anastrozole Tablets

1,190 flagged reaction(s) · 101,213 total co-reports · max PRR 265.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Performance Enhancing Product Use 20 265.5 265.7 signal
2 Amaurosis Fugax 222 258.0 260.7 signal
3 Vitreoretinal Traction Syndrome 15 188.8 188.9 signal
4 Pik3ca-activated Mutation 47 165.6 166.0 signal
5 Pseudocirrhosis 45 156.3 156.6 signal
6 Human Rhinovirus Test Positive 51 155.9 156.3 signal
7 Musculoskeletal Toxicity 22 133.2 133.4 signal
8 Carbohydrate Antigen 15-3 Increased 77 110.5 110.9 signal
9 Pleural Neoplasm 16 105.5 105.6 signal
10 Viral Test Positive 35 103.7 103.9 signal
11 Metastases To Breast 31 102.9 103.0 signal
12 Chest Wall Mass 22 91.1 91.2 signal
13 Metastases To Spinal Cord 16 88.1 88.2 signal
14 Pneumonia Haemophilus 40 87.9 88.1 signal
15 Metastases To Chest Wall 28 86.4 86.5 signal
16 Metastases To Thorax 20 83.9 84.0 signal
17 Secondary Hypogonadism 25 81.0 81.1 signal
18 Pseudocellulitis 16 80.3 80.4 signal
19 Metastases To The Mediastinum 31 79.3 79.4 signal
20 Respiratory Syncytial Virus Test Positive 52 78.2 78.4 signal
21 Hormone Receptor Positive Breast Cancer 16 63.5 63.6 signal
22 Breast Cancer Recurrent 190 63.0 63.6 signal
23 Tumour Marker Abnormal 20 62.3 62.4 signal
24 Metastases To Pelvis 35 57.7 57.8 signal
25 Scan Abnormal 20 56.3 56.4 signal
26 Metastases To Bone 789 49.8 51.7 signal
27 Metastases To Ovary 15 48.8 48.8 signal
28 Urinary Tract Disorder 202 46.2 46.6 signal
29 Metastases To Spine 147 45.1 45.4 signal
30 Invasive Lobular Breast Carcinoma 20 39.9 39.9 signal
31 Breast Cancer Metastatic 408 38.8 39.6 signal
32 Blood Albumin Abnormal 19 37.8 37.8 signal
33 Invasive Breast Carcinoma 15 37.0 37.0 signal
34 Metastases To Pleura 37 36.2 36.2 signal
35 Hair Disorder 280 34.1 34.6 signal
36 Tumour Marker Increased 154 32.5 32.7 signal
37 Metastases To Bone Marrow 16 32.2 32.3 signal
38 Tonsillar Disorder 35 31.4 31.4 signal
39 Haemorrhagic Stroke 242 31.2 31.5 signal
40 Metastases To Lung 353 31.0 31.5 signal
41 Fasciitis 20 30.9 30.9 signal
42 Tongue Injury 26 28.0 28.0 signal
43 Metastases To Liver 471 27.1 27.7 signal
44 Retinal Toxicity 27 26.8 26.8 signal
45 Invasive Ductal Breast Carcinoma 72 26.7 26.8 signal
46 Metastases To Lymph Nodes 173 26.0 26.2 signal
47 Madarosis 298 25.7 26.0 signal
48 Metastases To Skin 26 25.6 25.6 signal
49 Hair Colour Changes 317 25.4 25.8 signal
50 Atrophic Vulvovaginitis 18 24.9 24.9 signal
51 Decreased Immune Responsiveness 241 24.8 25.1 signal
52 Hair Texture Abnormal 332 24.8 25.2 signal
53 Blood Alkaline Phosphatase Abnormal 22 24.7 24.7 signal
54 Peritoneal Disorder 16 24.7 24.7 signal
55 Trigger Finger 97 24.0 24.2 signal
56 Mast Cell Activation Syndrome 31 23.5 23.6 signal
57 Glomerular Filtration Rate Increased 19 23.5 23.5 signal
58 Psychological Trauma 204 23.5 23.7 signal
59 Bone Lesion 84 23.4 23.5 signal
60 Bladder Irritation 14 22.2 22.3 signal
61 Axillary Mass 23 22.2 22.2 signal
62 Ocular Discomfort 240 22.2 22.4 signal
63 Ovarian Mass 16 21.8 21.8 signal
64 Vulvovaginal Dryness 69 21.5 21.6 signal
65 Intraductal Proliferative Breast Lesion 27 21.5 21.5 signal
66 Mean Cell Haemoglobin Increased 34 20.5 20.6 signal
67 Reflux Gastritis 24 20.2 20.2 signal
68 Osteolysis 41 20.0 20.1 signal
69 Pelvic Mass 16 19.9 19.9 signal
70 Nasal Disorder 52 19.5 19.6 signal
71 Tongue Biting 40 19.3 19.4 signal
72 Osteosclerosis 30 19.0 19.1 signal
73 Metastasis 133 18.5 18.7 signal
74 Macrocytosis 21 18.0 18.0 signal
75 Oestrogen Receptor Assay Positive 20 17.4 17.4 signal
76 Malignant Pleural Effusion 29 17.2 17.2 signal
77 Generalised Oedema 210 17.0 17.2 signal
78 Mesenteric Vein Thrombosis 17 17.0 17.0 signal
79 Blood Bilirubin Abnormal 21 16.5 16.5 signal
80 Head Discomfort 287 16.3 16.5 signal
81 Gene Mutation 32 16.1 16.1 signal
82 Progesterone Receptor Assay Positive 15 15.8 15.8 signal
83 Excessive Eye Blinking 23 15.5 15.5 signal
84 Sialoadenitis 21 15.4 15.4 signal
85 Second Primary Malignancy 128 15.4 15.4 signal
86 Nail Infection 22 15.3 15.3 signal
87 Cystoid Macular Oedema 28 15.0 15.0 signal
88 Radiation Injury 16 15.0 15.0 signal
89 Hepatic Mass 28 14.5 14.5 signal
90 Breast Discomfort 15 14.5 14.5 signal
91 Vitiligo 33 14.3 14.3 signal
92 Neutrophil Count Abnormal 39 13.8 13.8 signal
93 Mastitis 26 13.7 13.7 signal
94 Eastern Cooperative Oncology Group Performance Status Worsened 17 13.6 13.6 signal
95 Metastatic Neoplasm 58 13.4 13.4 signal
96 Alanine Aminotransferase Abnormal 28 13.3 13.3 signal
97 Blood Calcium Abnormal 22 13.2 13.2 signal
98 Lymphoedema 88 12.7 12.7 signal
99 Breast Mass 84 12.4 12.5 signal
100 Mean Cell Volume Increased 32 12.4 12.4 signal
101 Superinfection 18 11.9 11.9 signal
102 Ascites 351 11.9 12.0 signal
103 Breast Disorder 24 11.7 11.7 signal
104 Discouragement 27 11.6 11.6 signal
105 Menopausal Symptoms 25 10.9 10.9 signal
106 Atypical Femur Fracture 31 10.8 10.9 signal
107 Altered State Of Consciousness 234 10.8 10.9 signal
108 Polycythaemia 22 10.7 10.7 signal
109 Acquired Gene Mutation 14 10.5 10.5 signal
110 Neoplasm Progression 368 10.4 10.6 signal
111 Insulin-like Growth Factor Increased 15 10.4 10.4 signal
112 Ejection Fraction Decreased 163 10.4 10.5 signal
113 Hepatic Lesion 45 10.3 10.4 signal
114 Portal Hypertension 32 10.3 10.3 signal
115 Malignant Neoplasm Progression 1,051 10.2 10.7 signal
116 Alopecia Areata 18 10.2 10.2 signal
117 Subacute Cutaneous Lupus Erythematosus 18 10.1 10.1 signal
118 Photophobia 190 10.1 10.2 signal
119 Presyncope 239 9.8 9.9 signal
120 Red Cell Distribution Width Increased 41 9.8 9.8 signal
121 Carcinoembryonic Antigen Increased 19 9.8 9.8 signal
122 Metastases To Central Nervous System 126 9.8 9.8 signal
123 Bicytopenia 19 9.7 9.7 signal
124 White Blood Cell Disorder 26 9.6 9.6 signal
125 Haematemesis 244 9.5 9.6 signal
126 Bone Cancer 41 9.3 9.3 signal
127 Diplopia 243 9.3 9.4 signal
128 Cancer Pain 24 9.3 9.3 signal
129 Mastectomy 16 9.1 9.1 signal
130 White Blood Cell Count Abnormal 58 9.0 9.0 signal
131 Skin Atrophy 52 9.0 9.0 signal
132 Nail Disorder 78 8.9 8.9 signal
133 Lymphadenopathy Mediastinal 17 8.9 8.9 signal
134 Gingival Recession 17 8.8 8.8 signal
135 Bone Pain 518 8.8 8.9 signal
136 Metastases To Peritoneum 22 8.7 8.7 signal
137 Spinal Pain 102 8.6 8.7 signal
138 Dengue Fever 20 8.6 8.6 signal
139 Menopause 22 8.5 8.6 signal
140 Neoplasm Recurrence 29 8.5 8.5 signal
141 Polyneuropathy 101 8.4 8.4 signal
142 Mouth Haemorrhage 61 8.2 8.3 signal
143 Hepatic Cyst 28 8.2 8.2 signal
144 Osteonecrosis Of Jaw 197 7.8 7.9 signal
145 Blood Testosterone Increased 17 7.8 7.8 signal
146 Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis 19 7.7 7.7 signal
147 Eosinophil Count Decreased 18 7.7 7.7 signal
148 Onychoclasis 52 7.5 7.5 signal
149 White Blood Cell Count Decreased 817 7.5 7.7 signal
150 Breast Pain 80 7.4 7.4 signal
151 Pathological Fracture 38 7.4 7.4 signal
152 Radiation Pneumonitis 16 7.4 7.4 signal
153 Acute Lymphocytic Leukaemia 21 7.3 7.3 signal
154 Red Blood Cell Count Decreased 211 7.3 7.4 signal
155 Alopecia 1,444 7.3 7.7 signal
156 Blood Creatinine Abnormal 25 7.2 7.2 signal
157 Full Blood Count Decreased 146 7.2 7.2 signal
158 Full Blood Count Abnormal 76 7.1 7.2 signal
159 Adenocarcinoma 16 7.0 7.0 signal
160 Osteopenia 108 7.0 7.0 signal
161 Hot Flush 530 7.0 7.1 signal
162 Breast Cancer 659 6.9 7.1 signal
163 Pulmonary Pain 20 6.9 6.9 signal
164 Mouth Swelling 40 6.9 6.9 signal
165 Pulmonary Mass 102 6.8 6.8 signal
166 Plantar Fasciitis 23 6.8 6.8 signal
167 Trichorrhexis 19 6.7 6.7 signal
168 Sensitive Skin 49 6.7 6.7 signal
169 Osteitis 17 6.6 6.6 signal
170 Breast Cancer Stage Iv 19 6.5 6.5 signal
171 Blindness 269 6.5 6.6 signal
172 Impaired Quality Of Life 94 6.5 6.5 signal
173 Haematuria 221 6.4 6.4 signal
174 Skin Hypertrophy 18 6.3 6.4 signal
175 Carbohydrate Antigen 125 Increased 22 6.3 6.3 signal
176 Cerebral Thrombosis 18 6.3 6.3 signal
177 Poor Peripheral Circulation 27 6.2 6.2 signal
178 Leukopenia 313 6.2 6.3 signal
179 Musculoskeletal Chest Pain 97 6.2 6.2 signal
180 Bone Disorder 115 6.2 6.2 signal
181 Neutropenia 845 6.2 6.4 signal
182 Lung Opacity 16 6.1 6.1 signal
183 Nasal Dryness 38 6.0 6.0 signal
184 Abdominal Mass 16 5.9 5.9 signal
185 Recurrent Cancer 24 5.8 5.9 signal
186 Dermatomyositis 15 5.8 5.8 signal
187 Nail Discolouration 23 5.8 5.8 signal
188 Rhinalgia 16 5.8 5.8 signal
189 Neoplasm 67 5.7 5.8 signal
190 Hair Growth Abnormal 40 5.7 5.7 signal
191 Haemoglobin Increased 26 5.7 5.7 signal
192 Growth Retardation 17 5.7 5.7 signal
193 Tinnitus 262 5.6 5.7 signal
194 Eye Pain 314 5.6 5.7 signal
195 Pigmentation Disorder 35 5.6 5.6 signal
196 Hypersensitivity Vasculitis 15 5.6 5.6 signal
197 Hypovolaemia 33 5.6 5.6 signal
198 Autoimmune Hepatitis 39 5.6 5.6 signal
199 Lacrimation Increased 168 5.6 5.6 signal
200 Cutaneous Vasculitis 20 5.5 5.5 signal
201 Synovial Cyst 26 5.5 5.5 signal
202 Neutrophil Count Decreased 226 5.5 5.6 signal
203 Cardio-respiratory Arrest 234 5.5 5.5 signal
204 Breast Swelling 15 5.5 5.5 signal
205 Brain Fog 80 5.4 5.4 signal
206 Blood Chloride Decreased 14 5.3 5.3 signal
207 Haemoglobin Abnormal 34 5.2 5.3 signal
208 Neck Mass 15 5.2 5.2 signal
209 Organising Pneumonia 26 5.2 5.2 signal
210 Papilloedema 24 5.2 5.2 signal
211 Gingival Swelling 23 5.2 5.2 signal
212 Breast Enlargement 17 5.1 5.1 signal
213 Hypoventilation 17 5.1 5.1 signal
214 Feeding Disorder 103 5.1 5.1 signal
215 Left Ventricular Dysfunction 34 5.0 5.0 signal
216 Body Height Decreased 55 5.0 5.0 signal
217 Rhinitis 41 5.0 5.0 signal
218 Carpal Tunnel Syndrome 71 5.0 5.0 signal
219 Hepatotoxicity 112 5.0 5.0 signal
220 Uterine Leiomyoma 37 5.0 5.0 signal
221 Hiatus Hernia 65 4.9 5.0 signal
222 Coma 238 4.9 5.0 signal
223 Aphthous Ulcer 38 4.9 4.9 signal
224 Monocyte Count Increased 18 4.9 4.9 signal
225 Blood Phosphorus Decreased 18 4.9 4.9 signal
226 Fracture 93 4.8 4.9 signal
227 Panic Disorder 19 4.8 4.8 signal
228 Oral Pain 109 4.8 4.8 signal
229 Taste Disorder 97 4.8 4.8 signal
230 Thyroid Mass 18 4.7 4.7 signal
231 Phlebitis 24 4.6 4.6 signal
232 Cardiac Failure Acute 31 4.6 4.6 signal
233 Vein Disorder 23 4.5 4.5 signal
234 Autoimmune Thyroiditis 17 4.5 4.5 signal
235 Vaginal Discharge 45 4.4 4.4 signal
236 Nodule 58 4.4 4.4 signal
237 Hepatic Pain 19 4.4 4.4 signal
238 Dry Throat 45 4.4 4.4 signal
239 Hypercalcaemia 54 4.3 4.3 signal
240 Concomitant Disease Aggravated 27 4.3 4.3 signal
241 Hospice Care 43 4.3 4.3 signal
242 Palmar-plantar Erythrodysaesthesia Syndrome 102 4.3 4.3 signal
243 Lymphocyte Count Decreased 77 4.3 4.3 signal
244 Tooth Extraction 54 4.3 4.3 signal
245 Feeling Of Despair 20 4.2 4.2 signal
246 Mucosal Inflammation 112 4.2 4.3 signal
247 Cardiotoxicity 38 4.2 4.2 signal
248 Rhinitis Allergic 19 4.2 4.2 signal
249 Glossitis 15 4.2 4.2 signal
250 Breast Cancer Female 113 4.1 4.2 signal
251 Sleep Disorder Due To General Medical Condition, Insomnia Type 27 4.1 4.1 signal
252 Eating Disorder 89 4.1 4.1 signal
253 Spinal Cord Compression 16 4.0 4.0 signal
254 Stomatitis 248 4.0 4.1 signal
255 Neuropathy Peripheral 386 4.0 4.1 signal
256 Disease Progression 481 4.0 4.1 signal
257 Haematocrit Decreased 81 4.0 4.0 signal
258 Tongue Discomfort 17 4.0 4.0 signal
259 Tibia Fracture 19 4.0 4.0 signal
260 Musculoskeletal Discomfort 69 4.0 4.0 signal
261 Pain In Jaw 113 3.9 3.9 signal
262 Ischaemic Stroke 71 3.9 3.9 signal
263 Ear Disorder 18 3.9 3.9 signal
264 Spinal Disorder 37 3.8 3.8 signal
265 Haemorrhoids 76 3.8 3.8 signal
266 Joint Stiffness 102 3.8 3.8 signal
267 Ovarian Cancer 36 3.8 3.8 signal
268 Immunodeficiency 57 3.8 3.8 signal
269 Gastrointestinal Sounds Abnormal 19 3.8 3.8 signal
270 Acute Myeloid Leukaemia 60 3.8 3.8 signal
271 Lymphadenopathy 136 3.8 3.8 signal
272 Arthralgia 1,575 3.7 4.0 signal
273 Decreased Appetite 874 3.7 3.8 signal
274 Vulvovaginal Burning Sensation 23 3.7 3.7 signal
275 Peripheral Sensory Neuropathy 22 3.7 3.7 signal
276 Pleural Effusion 224 3.6 3.7 signal
277 Platelet Count Increased 48 3.6 3.6 signal
278 Tricuspid Valve Incompetence 29 3.6 3.6 signal
279 Toothache 66 3.6 3.6 signal
280 Flank Pain 34 3.6 3.6 signal
281 Pneumonitis 98 3.6 3.6 signal
282 Jaw Disorder 20 3.6 3.6 signal
283 Scab 41 3.6 3.6 signal
284 Cholestasis 69 3.6 3.6 signal
285 Skin Mass 24 3.6 3.6 signal
286 Myalgia 611 3.5 3.6 signal
287 Blood Count Abnormal 55 3.5 3.5 signal
288 Tachycardia 317 3.5 3.6 signal
289 Transaminases Increased 79 3.5 3.5 signal
290 Vascular Device Infection 16 3.5 3.5 signal
291 Dyslipidaemia 18 3.5 3.5 signal
292 Renal Pain 37 3.5 3.5 signal
293 Blood Alkaline Phosphatase Increased 87 3.4 3.5 signal
294 Vitamin D Deficiency 34 3.4 3.4 signal
295 Renal Function Test Abnormal 16 3.4 3.4 signal
296 Compression Fracture 18 3.4 3.4 signal
297 Osteoporosis 142 3.4 3.4 signal
298 Mass 48 3.4 3.4 signal
299 Meniscus Injury 21 3.4 3.4 signal
300 Tendonitis 53 3.4 3.4 signal
301 Vulvovaginal Discomfort 15 3.4 3.4 signal
302 Gastrointestinal Motility Disorder 18 3.3 3.3 signal
303 Hepatic Steatosis 63 3.3 3.3 signal
304 Drug-induced Liver Injury 103 3.3 3.3 signal
305 Arteriosclerosis Coronary Artery 22 3.3 3.3 signal
306 Hormone Level Abnormal 16 3.3 3.3 signal
307 Blood Lactate Dehydrogenase Increased 53 3.3 3.3 signal
308 Endocarditis 17 3.3 3.3 signal
309 Hyperthyroidism 48 3.3 3.3 signal
310 Abnormal Faeces 27 3.2 3.2 signal
311 Hepatic Cytolysis 40 3.2 3.2 signal
312 Chills 384 3.2 3.3 signal
313 Vitamin D Decreased 28 3.2 3.2 signal
314 Depressed Mood 171 3.2 3.2 signal
315 Lower Limb Fracture 62 3.2 3.2 signal
316 Hepatitis Acute 21 3.2 3.2 signal
317 Neuralgia 78 3.2 3.2 signal
318 Drug Intolerance 309 3.2 3.2 signal
319 Blood Test Abnormal 45 3.2 3.2 signal
320 Colitis Microscopic 15 3.1 3.1 signal
321 Blood Calcium Decreased 36 3.1 3.1 signal
322 Mitral Valve Incompetence 36 3.1 3.1 signal
323 Syncope 318 3.1 3.2 signal
324 Tooth Fracture 35 3.1 3.1 signal
325 Sarcoidosis 15 3.1 3.1 signal
326 Sluggishness 32 3.1 3.1 signal
327 Liver Function Test Increased 67 3.1 3.1 signal
328 Nasal Discomfort 25 3.1 3.1 signal
329 Oropharyngeal Discomfort 28 3.1 3.1 signal
330 Lip Dry 28 3.1 3.1 signal
331 Cytopenia 37 3.0 3.1 signal
332 Alanine Aminotransferase Increased 190 3.0 3.1 signal
333 Hydronephrosis 23 3.0 3.0 signal
334 Aspartate Aminotransferase Increased 163 3.0 3.0 signal
335 Parosmia 23 3.0 3.0 signal
336 Cough 854 3.0 3.1 signal
337 Platelet Count Decreased 325 3.0 3.0 signal
338 Urine Odour Abnormal 18 3.0 3.0 signal
339 Fatigue 2,364 3.0 3.2 signal
340 Mouth Ulceration 63 3.0 3.0 signal
341 Haemoglobin Decreased 308 2.9 3.0 signal
342 Skin Discolouration 137 2.9 2.9 signal
343 Tenderness 31 2.9 2.9 signal
344 Pelvic Fracture 23 2.9 2.9 signal
345 Thermal Burn 21 2.9 2.9 signal
346 Obstructive Airways Disorder 33 2.9 2.9 signal
347 Hypertensive Crisis 33 2.9 2.9 signal
348 Electrocardiogram Qt Prolonged 105 2.9 2.9 signal
349 Visual Field Defect 21 2.9 2.9 signal
350 Intervertebral Disc Degeneration 27 2.9 2.9 signal
351 Vision Blurred 396 2.9 2.9 signal
352 Osteonecrosis 96 2.9 2.9 signal
353 Joint Effusion 20 2.8 2.8 signal
354 Cerebral Ischaemia 15 2.8 2.8 signal
355 Tooth Infection 38 2.8 2.8 signal
356 Weight Fluctuation 30 2.8 2.8 signal
357 Muscle Tightness 46 2.8 2.8 signal
358 Wound 79 2.8 2.8 signal
359 Pelvic Pain 51 2.8 2.8 signal
360 Dysstasia 82 2.8 2.8 signal
361 Dyspnoea Exertional 105 2.8 2.8 signal
362 Diarrhoea 1,792 2.7 2.9 signal
363 Blood Pressure Abnormal 55 2.7 2.7 signal
364 Cardiomyopathy 41 2.7 2.7 signal
365 Constipation 599 2.7 2.8 signal
366 Dry Skin 364 2.7 2.8 signal
367 Gingival Pain 22 2.7 2.7 signal
368 Ageusia 69 2.7 2.7 signal
369 Asthenia 1,036 2.7 2.8 signal
370 Interstitial Lung Disease 133 2.7 2.7 signal
371 Insomnia 733 2.7 2.8 signal
372 Pulmonary Thrombosis 30 2.7 2.7 signal
373 Immune System Disorder 36 2.7 2.7 signal
374 Glossodynia 61 2.7 2.7 signal
375 Retching 58 2.7 2.7 signal
376 Sepsis 304 2.7 2.7 signal
377 Neutrophil Count Increased 28 2.7 2.7 signal
378 Oral Disorder 20 2.7 2.7 signal
379 Retinal Detachment 25 2.7 2.7 signal
380 Purpura 24 2.7 2.7 signal
381 Blood Pressure Increased 415 2.7 2.7 signal
382 Dry Eye 131 2.7 2.7 signal
383 Gastritis 71 2.7 2.7 signal
384 Hiccups 22 2.7 2.7 signal
385 Haematotoxicity 25 2.7 2.7 signal
386 Skin Toxicity 15 2.6 2.6 signal
387 Skin Disorder 89 2.6 2.6 signal
388 Disease Recurrence 127 2.6 2.6 signal
389 Tooth Disorder 59 2.6 2.6 signal
390 Renal Cyst 21 2.6 2.6 signal
391 Movement Disorder 85 2.6 2.6 signal
392 Spinal Fracture 52 2.6 2.6 signal
393 Hypophosphataemia 19 2.5 2.5 signal
394 Dysgeusia 193 2.5 2.6 signal
395 Facial Pain 23 2.5 2.5 signal
396 Liver Disorder 114 2.5 2.5 signal
397 Asthenopia 14 2.5 2.5 signal
398 Gamma-glutamyltransferase Increased 57 2.5 2.5 signal
399 Oesophagitis 28 2.5 2.5 signal
400 Glomerular Filtration Rate Decreased 31 2.5 2.5 signal
401 Blood Creatinine Increased 167 2.5 2.5 signal
402 Limb Discomfort 79 2.5 2.5 signal
403 Anaemia 487 2.5 2.5 signal
404 Arteriosclerosis 24 2.5 2.5 signal
405 Tooth Abscess 26 2.5 2.5 signal
406 Ligament Sprain 25 2.5 2.5 signal
407 Drug Interaction 399 2.5 2.5 signal
408 Pharyngeal Swelling 24 2.5 2.5 signal
409 Impaired Healing 82 2.5 2.5 signal
410 Skin Fissures 47 2.5 2.5 signal
411 Ecchymosis 17 2.4 2.4 signal
412 Anal Incontinence 22 2.4 2.4 signal
413 Respiratory Rate Increased 22 2.4 2.4 signal
414 Blood Testosterone Decreased 17 2.4 2.4 signal
415 Infarction 17 2.4 2.4 signal
416 Skin Lesion 67 2.4 2.4 signal
417 Swelling Of Eyelid 15 2.4 2.4 signal
418 Abdominal Pain Upper 505 2.4 2.5 signal
419 Central Nervous System Lesion 34 2.4 2.4 signal
420 Discomfort 149 2.4 2.4 signal
421 Atrioventricular Block 19 2.4 2.4 signal
422 Uveitis 33 2.4 2.4 signal
423 Dry Mouth 197 2.4 2.4 signal
424 Osteomyelitis 44 2.4 2.4 signal
425 Oropharyngeal Pain 225 2.4 2.4 signal
426 Hyperlipidaemia 29 2.4 2.4 signal
427 Abdominal Pain 562 2.4 2.4 signal
428 Pain In Extremity 713 2.4 2.4 signal
429 Laboratory Test Abnormal 71 2.4 2.4 signal
430 Embolism 20 2.4 2.4 signal
431 Nausea 1,887 2.4 2.5 signal
432 Memory Impairment 329 2.4 2.4 signal
433 Mood Swings 76 2.3 2.3 signal
434 Myelosuppression 81 2.3 2.3 signal
435 Spinal Osteoarthritis 21 2.3 2.3 signal
436 Photopsia 15 2.3 2.3 signal
437 Tendon Pain 18 2.3 2.3 signal
438 Abdominal Discomfort 396 2.3 2.4 signal
439 Thrombocytopenia 264 2.3 2.3 signal
440 Blood Bilirubin Increased 64 2.3 2.3 signal
441 Cellulitis 119 2.3 2.3 signal
442 Dental Caries 26 2.3 2.3 signal
443 Eye Discharge 24 2.3 2.3 signal
444 Oral Mucosal Blistering 15 2.3 2.3 signal
445 Breast Cancer Stage I 22 2.3 2.3 signal
446 Poor Quality Sleep 50 2.3 2.3 signal
447 Wrist Fracture 28 2.3 2.3 signal
448 Sciatica 37 2.3 2.3 signal
449 Osteoarthritis 99 2.3 2.3 signal
450 Lupus-like Syndrome 21 2.3 2.3 signal
451 Vasculitis 27 2.3 2.3 signal
452 Foot Fracture 44 2.3 2.3 signal
453 Peripheral Swelling 355 2.3 2.3 signal
454 Somnolence 463 2.3 2.3 signal
455 Papule 16 2.3 2.3 signal
456 Psychiatric Symptom 17 2.3 2.3 signal
457 Rib Fracture 47 2.3 2.3 signal
458 Epistaxis 171 2.2 2.3 signal
459 Skin Exfoliation 189 2.2 2.2 signal
460 Product Dose Omission In Error 61 2.2 2.2 signal
461 Gait Inability 75 2.2 2.2 signal
462 Choking 44 2.2 2.2 signal
463 Acute Respiratory Failure 43 2.2 2.2 signal
464 Sleep Disorder 157 2.2 2.2 signal
465 Thirst 40 2.2 2.2 signal
466 Dyspepsia 220 2.2 2.2 signal
467 Back Pain 520 2.2 2.2 signal
468 Quality Of Life Decreased 30 2.2 2.2 signal
469 Jaundice 60 2.2 2.2 signal
470 Drug Resistance 57 2.2 2.2 signal
471 Skin Hyperpigmentation 19 2.2 2.2 signal
472 Product Administration Interrupted 17 2.2 2.2 signal
473 Upper Respiratory Tract Infection 102 2.2 2.2 signal
474 Posterior Reversible Encephalopathy Syndrome 21 2.2 2.2 signal
475 Myopathy 19 2.2 2.2 signal
476 Liver Function Test Abnormal 64 2.2 2.2 signal
477 Increased Appetite 41 2.1 2.1 signal
478 Night Sweats 70 2.1 2.1 signal
479 Cystitis 69 2.1 2.1 signal
480 Hunger 29 2.1 2.1 signal
481 Subarachnoid Haemorrhage 22 2.1 2.1 signal
482 Aphonia 30 2.1 2.1 signal
483 Rash Pruritic 116 2.1 2.1 signal
484 Vomiting 1,008 2.1 2.2 signal
485 Nocturia 26 2.1 2.1 signal
486 Pruritus 811 2.1 2.2 signal
487 Spinal Compression Fracture 18 2.1 2.1 signal
488 Fear 58 2.1 2.1 signal
489 Pulmonary Toxicity 15 2.1 2.1 signal
490 Gastrooesophageal Reflux Disease 171 2.1 2.1 signal
491 Hypophagia 54 2.1 2.1 signal
492 Therapy Partial Responder 32 2.1 2.1 signal
493 Blood Iron Decreased 25 2.1 2.1 signal
494 Micturition Urgency 24 2.1 2.1 signal
495 Ventricular Extrasystoles 22 2.1 2.1 signal
496 Productive Cough 100 2.1 2.1 signal
497 Skeletal Injury 22 2.1 2.1 signal
498 Gait Disturbance 403 2.1 2.1 signal
499 Femur Fracture 65 2.1 2.1 signal
500 Muscle Disorder 17 2.1 2.1 signal
501 Dizziness 1,033 2.0 2.1 signal
502 Faeces Soft 15 2.0 2.0 signal
503 Visual Impairment 254 2.0 2.0 signal
504 Acute Hepatic Failure 28 2.0 2.0 signal
505 Burning Sensation 144 2.0 2.0 signal
506 Flatulence 116 2.0 2.0 signal
507 Rhinorrhoea 132 2.0 2.0 signal
508 Fall 680 2.0 2.0 signal
509 Groin Pain 18 2.0 2.0 signal
510 Affective Disorder 16 2.0 2.0 signal
511 Illness 205 2.0 2.0 signal
512 Pain Of Skin 55 2.0 2.0 signal
513 Blood Triglycerides Increased 36 2.0 2.0 no signal
514 Faeces Discoloured 44 2.0 2.0 no signal
515 Hepatomegaly 20 2.0 2.0 no signal
516 Hypomagnesaemia 28 2.0 2.0 no signal
517 Skin Plaque 17 2.0 2.0 no signal
518 Product Substitution Issue 116 2.0 2.0 no signal
519 Device Physical Property Issue 15 2.0 2.0 no signal
520 Eructation 38 2.0 2.0 no signal
521 Lactic Acidosis 64 2.0 2.0 no signal
522 Malaise 876 2.0 2.0 no signal
523 Blood Pressure Systolic Increased 39 2.0 2.0 no signal
524 Muscle Atrophy 25 2.0 2.0 no signal
525 Dysphonia 116 2.0 2.0 no signal
526 Red Blood Cell Sedimentation Rate Increased 22 2.0 2.0 no signal
527 Foot Deformity 22 2.0 2.0 no signal
528 Sensory Loss 16 1.9 2.0 no signal
529 Dermatitis 41 1.9 1.9 no signal
530 Weight Decreased 552 1.9 2.0 no signal
531 Hysterectomy 17 1.9 1.9 no signal
532 Blood Magnesium Decreased 17 1.9 1.9 no signal
533 Blood Potassium Decreased 59 1.9 1.9 no signal
534 Increased Tendency To Bruise 18 1.9 1.9 no signal
535 Swollen Tongue 61 1.9 1.9 no signal
536 Secretion Discharge 24 1.9 1.9 no signal
537 Nervousness 102 1.9 1.9 no signal
538 Poor Venous Access 20 1.9 1.9 no signal
539 Hip Fracture 62 1.9 1.9 no signal
540 Depression 441 1.9 1.9 no signal
541 Dysuria 71 1.9 1.9 no signal
542 Pharyngitis 24 1.9 1.9 no signal
543 Petechiae 20 1.9 1.9 no signal
544 Dyspnoea 1,087 1.9 1.9 no signal
545 Bone Marrow Failure 39 1.9 1.9 no signal
546 Electrocardiogram Abnormal 15 1.9 1.9 no signal
547 Paraesthesia 300 1.9 1.9 no signal
548 Gingival Bleeding 26 1.9 1.9 no signal
549 Blood Urea Increased 32 1.9 1.9 no signal
550 Epilepsy 58 1.9 1.9 no signal
551 Hyperglycaemia 69 1.9 1.9 no signal
552 Thrombosis 153 1.9 1.9 no signal
553 Musculoskeletal Stiffness 166 1.9 1.9 no signal
554 Urinary Tract Infection 322 1.9 1.9 no signal
555 Headache 1,183 1.9 1.9 no signal
556 Dehydration 252 1.9 1.9 no signal
557 Skin Swelling 16 1.9 1.9 no signal
558 Throat Irritation 84 1.8 1.9 no signal
559 Ventricular Tachycardia 31 1.8 1.8 no signal
560 Dysphagia 177 1.8 1.8 no signal
561 Decreased Activity 20 1.8 1.8 no signal
562 Rash Macular 65 1.8 1.8 no signal
563 Exostosis 17 1.8 1.8 no signal
564 Libido Decreased 23 1.8 1.8 no signal
565 Cataract 110 1.8 1.8 no signal
566 Hypocalcaemia 35 1.8 1.8 no signal
567 Cardiomegaly 23 1.8 1.8 no signal
568 Covid-19 328 1.8 1.8 no signal
569 Ear Pain 36 1.8 1.8 no signal
570 Bone Loss 28 1.8 1.8 no signal
571 Neurotoxicity 32 1.8 1.8 no signal
572 Eye Disorder 60 1.8 1.8 no signal
573 Cholelithiasis 60 1.8 1.8 no signal
574 Grip Strength Decreased 16 1.8 1.8 no signal
575 Blood Cholesterol Increased 85 1.8 1.8 no signal
576 Blood Calcium Increased 16 1.8 1.8 no signal
577 Abdominal Distension 189 1.8 1.8 no signal
578 Tubulointerstitial Nephritis 34 1.8 1.8 no signal
579 Hyperaesthesia 15 1.8 1.8 no signal
580 Paraesthesia Oral 26 1.8 1.8 no signal
581 Renal Impairment 151 1.8 1.8 no signal
582 Nasopharyngitis 333 1.8 1.8 no signal
583 Neoplasm Malignant 120 1.8 1.8 no signal
584 Hypoaesthesia Oral 27 1.8 1.8 no signal
585 Hypokinesia 26 1.8 1.8 no signal
586 Blister 100 1.8 1.8 no signal
587 Bacteraemia 21 1.8 1.8 no signal
588 Pyrexia 616 1.8 1.8 no signal
589 Hyponatraemia 100 1.8 1.8 no signal
590 Balance Disorder 154 1.7 1.8 no signal
591 Liver Injury 43 1.7 1.8 no signal
592 Pancytopenia 99 1.7 1.8 no signal
593 Abdominal Pain Lower 45 1.7 1.7 no signal
594 Inflammation 91 1.7 1.7 no signal
595 Seasonal Allergy 25 1.7 1.7 no signal
596 Dizziness Postural 17 1.7 1.7 no signal
597 Hypoaesthesia 265 1.7 1.7 no signal
598 Myocarditis 20 1.7 1.7 no signal
599 Dermatitis Allergic 22 1.7 1.7 no signal
600 Anxiety 503 1.7 1.8 no signal
601 Macular Degeneration 21 1.7 1.7 no signal
602 Muscle Spasms 322 1.7 1.7 no signal
603 Optic Neuritis 16 1.7 1.7 no signal
604 Drug Level Increased 29 1.7 1.7 no signal
605 Vertigo 106 1.7 1.7 no signal
606 Muscle Strain 15 1.7 1.7 no signal
607 Anaphylactic Reaction 95 1.7 1.7 no signal
608 Influenza 193 1.7 1.7 no signal
609 Pulmonary Hypertension 36 1.7 1.7 no signal
610 Hypokalaemia 79 1.7 1.7 no signal
611 Acute Kidney Injury 262 1.7 1.7 no signal
612 Cardiac Failure 137 1.7 1.7 no signal
613 Arrhythmia 81 1.7 1.7 no signal
614 Cognitive Disorder 79 1.7 1.7 no signal
615 Product Distribution Issue 15 1.7 1.7 no signal
616 Arthritis 133 1.7 1.7 no signal
617 Irritable Bowel Syndrome 36 1.7 1.7 no signal
618 Toxic Skin Eruption 17 1.7 1.7 no signal
619 Pollakiuria 70 1.7 1.7 no signal
620 Deafness 44 1.7 1.7 no signal
621 Ankle Fracture 26 1.6 1.7 no signal
622 Hypoacusis 72 1.6 1.7 no signal
623 Pain 1,029 1.6 1.7 no signal
624 Hypercholesterolaemia 16 1.6 1.6 no signal
625 Pulmonary Embolism 159 1.6 1.6 no signal
626 Pharyngitis Streptococcal 18 1.6 1.6 no signal
627 Limb Injury 45 1.6 1.6 no signal
628 Mood Altered 45 1.6 1.6 no signal
629 Urinary Incontinence 49 1.6 1.6 no signal
630 Pericardial Effusion 38 1.6 1.6 no signal
631 Atelectasis 16 1.6 1.6 no signal
632 Head Injury 52 1.6 1.6 no signal
633 Oral Herpes 32 1.6 1.6 no signal
634 Chest Pain 305 1.6 1.6 no signal
635 Stress 118 1.6 1.6 no signal
636 Iron Deficiency Anaemia 15 1.6 1.6 no signal
637 Brain Neoplasm 15 1.6 1.6 no signal
638 Feeling Hot 100 1.6 1.6 no signal
639 Renal Tubular Necrosis 16 1.6 1.6 no signal
640 Device Related Infection 25 1.6 1.6 no signal
641 Sinus Disorder 32 1.6 1.6 no signal
642 Nasal Congestion 94 1.6 1.6 no signal
643 Hypertension 339 1.6 1.6 no signal
644 Feeling Abnormal 384 1.6 1.6 no signal
645 Swelling 149 1.6 1.6 no signal
646 Chronic Kidney Disease 122 1.6 1.6 no signal
647 Contusion 153 1.6 1.6 no signal
648 Ovarian Cyst 16 1.6 1.6 no signal
649 Neck Pain 89 1.6 1.6 no signal
650 Musculoskeletal Pain 84 1.6 1.6 no signal
651 Joint Injury 34 1.6 1.6 no signal
652 Lower Respiratory Tract Infection 72 1.6 1.6 no signal
653 Hypoglycaemia 77 1.6 1.6 no signal
654 Emotional Disorder 49 1.6 1.6 no signal
655 Hypothermia 16 1.6 1.6 no signal
656 Bursitis 19 1.5 1.5 no signal
657 Ulcer 25 1.5 1.5 no signal
658 Myocardial Ischaemia 18 1.5 1.5 no signal
659 Supraventricular Tachycardia 15 1.5 1.5 no signal
660 General Physical Health Deterioration 180 1.5 1.5 no signal
661 Skin Reaction 22 1.5 1.5 no signal
662 Muscle Twitching 36 1.5 1.5 no signal
663 Diabetes Mellitus 119 1.5 1.5 no signal
664 Hypersensitivity 288 1.5 1.5 no signal
665 Hepatocellular Injury 22 1.5 1.5 no signal
666 Scratch 16 1.5 1.5 no signal
667 Product Odour Abnormal 16 1.5 1.5 no signal
668 Vitreous Floaters 15 1.5 1.5 no signal
669 Crying 56 1.5 1.5 no signal
670 Emotional Distress 186 1.5 1.5 no signal
671 Hepatic Enzyme Increased 104 1.5 1.5 no signal
672 Frequent Bowel Movements 41 1.5 1.5 no signal
673 Scar 26 1.5 1.5 no signal
674 Apathy 22 1.5 1.5 no signal
675 Weight Increased 337 1.5 1.5 no signal
676 Rectal Haemorrhage 65 1.5 1.5 no signal
677 Arthropathy 84 1.5 1.5 no signal
678 Haematoma 39 1.5 1.5 no signal
679 Herpes Zoster 86 1.5 1.5 no signal
680 Mobility Decreased 107 1.5 1.5 no signal
681 Lymphopenia 21 1.5 1.5 no signal
682 Gastroenteritis Viral 27 1.5 1.5 no signal
683 Skin Laceration 16 1.5 1.5 no signal
684 Atrial Fibrillation 144 1.5 1.5 no signal
685 Viral Infection 49 1.4 1.5 no signal
686 Device Mechanical Issue 19 1.4 1.4 no signal
687 Back Disorder 24 1.4 1.4 no signal
688 Glycosylated Haemoglobin Increased 37 1.4 1.4 no signal
689 Hypersomnia 42 1.4 1.4 no signal
690 Eye Pruritus 48 1.4 1.4 no signal
691 Glaucoma 28 1.4 1.4 no signal
692 Pneumothorax 23 1.4 1.4 no signal
693 Lung Disorder 71 1.4 1.4 no signal
694 Paranoia 25 1.4 1.4 no signal
695 Rash 625 1.4 1.4 no signal
696 Sinusitis 148 1.4 1.4 no signal
697 Tooth Loss 30 1.4 1.4 no signal
698 Fluid Retention 73 1.4 1.4 no signal
699 Speech Disorder 75 1.4 1.4 no signal
700 White Blood Cell Count Increased 55 1.4 1.4 no signal
701 Pulmonary Oedema 64 1.4 1.4 no signal
702 Hepatic Failure 43 1.4 1.4 no signal
703 Muscular Weakness 161 1.4 1.4 no signal
704 Cold Sweat 25 1.4 1.4 no signal
705 Body Temperature Increased 29 1.4 1.4 no signal
706 Product Taste Abnormal 19 1.4 1.4 no signal
707 Pulmonary Fibrosis 27 1.4 1.4 no signal
708 End Stage Renal Disease 26 1.4 1.4 no signal
709 Urosepsis 13 1.4 1.4 no signal
710 Therapy Cessation 72 1.4 1.4 no signal
711 Therapy Interrupted 97 1.4 1.4 no signal
712 Nervous System Disorder 44 1.4 1.4 no signal
713 Hepatic Function Abnormal 52 1.4 1.4 no signal
714 Fibromyalgia 34 1.4 1.4 no signal
715 Rotator Cuff Syndrome 18 1.4 1.4 no signal
716 Product Prescribing Error 33 1.4 1.4 no signal
717 Intentional Product Misuse 121 1.4 1.4 no signal
718 Skin Haemorrhage 20 1.4 1.4 no signal
719 Palpitations 162 1.4 1.4 no signal
720 Colitis 52 1.4 1.4 no signal
721 Gastrointestinal Disorder 122 1.4 1.4 no signal
722 Anosmia 20 1.4 1.4 no signal
723 Proteinuria 26 1.4 1.4 no signal
724 Diverticulitis 38 1.4 1.4 no signal
725 Chromaturia 31 1.3 1.3 no signal
726 Renal Disorder 64 1.3 1.3 no signal
727 Respiratory Failure 100 1.3 1.3 no signal
728 Localised Infection 33 1.3 1.3 no signal
729 Haemoptysis 38 1.3 1.3 no signal
730 Oedema Peripheral 166 1.3 1.3 no signal
731 Pneumonia 438 1.3 1.3 no signal
732 Sars-cov-2 Test Positive 18 1.3 1.3 no signal
733 Bacterial Infection 25 1.3 1.3 no signal
734 Irritability 81 1.3 1.3 no signal
735 Knee Operation 13 1.3 1.3 no signal
736 Hallucination, Visual 28 1.3 1.3 no signal
737 Hyperhidrosis 172 1.3 1.3 no signal
738 Amnesia 87 1.3 1.3 no signal
739 Infection 192 1.3 1.3 no signal
740 Cardiogenic Shock 19 1.3 1.3 no signal
741 Blood Pressure Decreased 88 1.3 1.3 no signal
742 Feeling Cold 37 1.3 1.3 no signal
743 Lip Swelling 44 1.3 1.3 no signal
744 Intervertebral Disc Protrusion 29 1.3 1.3 no signal
745 Inability To Afford Medication 13 1.3 1.3 no signal
746 Hypothyroidism 42 1.3 1.3 no signal
747 Abscess 21 1.3 1.3 no signal
748 Skin Ulcer 34 1.3 1.3 no signal
749 Oral Candidiasis 17 1.3 1.3 no signal
750 Lethargy 75 1.3 1.3 no signal
751 Upper Limb Fracture 26 1.3 1.3 no signal
752 Hernia 25 1.3 1.3 no signal
753 Blood Potassium Increased 21 1.3 1.3 no signal
754 Product Packaging Issue 12 1.3 1.3 no signal
755 Tendon Rupture 16 1.3 1.3 no signal
756 Swelling Face 84 1.3 1.3 no signal
757 Hepatitis 33 1.3 1.3 no signal
758 Sexual Dysfunction 15 1.3 1.3 no signal
759 Thinking Abnormal 24 1.3 1.3 no signal
760 Gastrointestinal Pain 14 1.3 1.3 no signal
761 Blood Sodium Decreased 24 1.3 1.3 no signal
762 Blood Glucose Fluctuation 14 1.3 1.3 no signal
763 Eye Haemorrhage 17 1.3 1.3 no signal
764 Ear Discomfort 13 1.2 1.2 no signal
765 Transient Ischaemic Attack 43 1.2 1.2 no signal
766 Product Use Issue 237 1.2 1.2 no signal
767 Haemorrhage Intracranial 19 1.2 1.2 no signal
768 Orthostatic Hypotension 22 1.2 1.2 no signal
769 Ataxia 15 1.2 1.2 no signal
770 Myoclonus 15 1.2 1.2 no signal
771 Nerve Injury 14 1.2 1.2 no signal
772 Skin Infection 14 1.2 1.2 no signal
773 Multiple Organ Dysfunction Syndrome 35 1.2 1.2 no signal
774 Ill-defined Disorder 76 1.2 1.2 no signal
775 Blood Pressure Fluctuation 30 1.2 1.2 no signal
776 Chest Discomfort 127 1.2 1.2 no signal
777 Joint Swelling 150 1.2 1.2 no signal
778 Local Swelling 22 1.2 1.2 no signal
779 Erythema 255 1.2 1.2 no signal
780 Face Oedema 21 1.2 1.2 no signal
781 Joint Dislocation 13 1.2 1.2 no signal
782 Rebound Effect 14 1.2 1.2 no signal
783 Thyroid Disorder 19 1.2 1.2 no signal
784 Hemiparesis 21 1.2 1.2 no signal
785 Hepatic Cirrhosis 23 1.2 1.2 no signal
786 Product Prescribing Issue 25 1.2 1.2 no signal
787 Circulatory Collapse 21 1.2 1.2 no signal
788 Febrile Neutropenia 81 1.2 1.2 no signal
789 Meningioma 18 1.2 1.2 no signal
790 Aphasia 37 1.2 1.2 no signal
791 Leukocytosis 22 1.2 1.2 no signal
792 Photosensitivity Reaction 20 1.2 1.2 no signal
793 Deep Vein Thrombosis 79 1.2 1.2 no signal
794 Blindness Unilateral 17 1.2 1.2 no signal
795 Cyst 15 1.2 1.2 no signal
796 Adverse Reaction 16 1.2 1.2 no signal
797 Product Availability Issue 27 1.2 1.2 no signal
798 Candida Infection 20 1.2 1.2 no signal
799 Blood Thyroid Stimulating Hormone Increased 11 1.2 1.2 no signal
800 Product Packaging Quantity Issue 13 1.2 1.2 no signal
801 Blood Glucose Abnormal 22 1.2 1.2 no signal
802 Cerebral Infarction 29 1.2 1.2 no signal
803 Sinus Congestion 16 1.2 1.2 no signal
804 Dystonia 23 1.2 1.2 no signal
805 Inappropriate Antidiuretic Hormone Secretion 12 1.2 1.2 no signal
806 Initial Insomnia 12 1.2 1.2 no signal
807 Confusional State 190 1.2 1.2 no signal
808 Condition Aggravated 354 1.2 1.2 no signal
809 Mental Disorder 51 1.2 1.2 no signal
810 Sneezing 26 1.1 1.1 no signal
811 Peripheral Coldness 16 1.1 1.1 no signal
812 Blood Urine Present 22 1.1 1.1 no signal
813 Renal Failure 154 1.1 1.1 no signal
814 Sleep Apnoea Syndrome 22 1.1 1.1 no signal
815 Serotonin Syndrome 22 1.1 1.1 no signal
816 Throat Tightness 31 1.1 1.1 no signal
817 Migraine 108 1.1 1.1 no signal
818 Eye Swelling 42 1.1 1.1 no signal
819 Diabetes Mellitus Inadequate Control 20 1.1 1.1 no signal
820 Pancreatitis Acute 25 1.1 1.1 no signal
821 Chronic Obstructive Pulmonary Disease 58 1.1 1.1 no signal
822 Urinary Retention 37 1.1 1.1 no signal
823 Bradycardia 59 1.1 1.1 no signal
824 Splenomegaly 13 1.1 1.1 no signal
825 Adverse Drug Reaction 99 1.1 1.1 no signal
826 Product Dose Omission Issue 315 1.1 1.1 no signal
827 Urticaria 184 1.1 1.1 no signal
828 Salivary Hypersecretion 11 1.1 1.1 no signal
829 Product Use Complaint 17 1.1 1.1 no signal
830 Brain Injury 11 1.1 1.1 no signal
831 Oxygen Saturation Decreased 61 1.1 1.1 no signal
832 Influenza Like Illness 90 1.1 1.1 no signal
833 Tremor 181 1.1 1.1 no signal
834 Emphysema 11 1.1 1.1 no signal
835 Rash Maculo-papular 24 1.1 1.1 no signal
836 Wheezing 64 1.1 1.1 no signal
837 Drug Eruption 19 1.1 1.1 no signal
838 Oral Discomfort 15 1.1 1.1 no signal
839 Temperature Intolerance 11 1.1 1.1 no signal
840 C-reactive Protein Increased 39 1.1 1.1 no signal
841 Surgery 62 1.1 1.1 no signal
842 Hallucination, Auditory 17 1.0 1.1 no signal
843 Coordination Abnormal 15 1.0 1.0 no signal
844 Nephropathy 10 1.0 1.0 no signal
845 Pallor 29 1.0 1.0 no signal
846 Gallbladder Disorder 19 1.0 1.0 no signal
847 Squamous Cell Carcinoma 10 1.0 1.0 no signal
848 Sinus Tachycardia 15 1.0 1.0 no signal
849 Heart Rate Irregular 24 1.0 1.0 no signal
850 Off Label Use 913 1.0 1.0 no signal
851 Musculoskeletal Disorder 20 1.0 1.0 no signal
852 Restless Legs Syndrome 19 1.0 1.0 no signal
853 Bone Density Decreased 33 1.0 1.0 no signal
854 Angina Pectoris 30 1.0 1.0 no signal
855 Nightmare 36 1.0 1.0 no signal
856 Bronchitis 77 1.0 1.0 no signal
857 Rhabdomyolysis 43 1.0 1.0 no signal
858 Renal Injury 31 1.0 1.0 no signal
859 Hypoxia 36 1.0 1.0 no signal
860 Eye Irritation 57 1.0 1.0 no signal
861 Oedema 55 1.0 1.0 no signal
862 Visual Acuity Reduced 34 1.0 1.0 no signal
863 Cyanosis 16 1.0 1.0 no signal
864 Suicidal Ideation 93 1.0 1.0 no signal
865 Acute Myocardial Infarction 30 1.0 1.0 no signal
866 Seizure 116 1.0 1.0 no signal
867 Covid-19 Pneumonia 12 1.0 1.0 no signal
868 Disorientation 40 1.0 1.0 no signal
869 Ocular Hyperaemia 47 1.0 1.0 no signal
870 Respiratory Tract Congestion 16 1.0 1.0 no signal
871 Nephrolithiasis 46 1.0 1.0 no signal
872 Obesity 16 1.0 1.0 no signal
873 Product Administration Error 20 1.0 1.0 no signal
874 Inappropriate Schedule Of Product Administration 177 1.0 1.0 no signal
875 Anger 34 1.0 1.0 no signal
876 Therapeutic Response Unexpected 45 1.0 1.0 no signal
877 Gastric Ulcer 19 1.0 1.0 no signal
878 Sleep Disorder Due To A General Medical Condition 16 1.0 1.0 no signal
879 Motor Dysfunction 10 1.0 1.0 no signal
880 Intestinal Obstruction 37 1.0 1.0 no signal
881 Post Procedural Complication 19 1.0 1.0 no signal
882 Dysarthria 37 1.0 1.0 no signal
883 Restlessness 36 1.0 1.0 no signal
884 Anhedonia 26 1.0 1.0 no signal
885 Disturbance In Attention 53 1.0 1.0 no signal
886 Nerve Compression 9 1.0 1.0 no signal
887 Procedural Pain 27 1.0 1.0 no signal
888 Paralysis 14 1.0 1.0 no signal
889 Hyperkalaemia 34 1.0 1.0 no signal
890 Abnormal Dreams 27 1.0 1.0 no signal
891 Impaired Driving Ability 11 0.9 0.9 no signal
892 Heart Rate Decreased 34 0.9 0.9 no signal
893 Acute Respiratory Distress Syndrome 17 0.9 0.9 no signal
894 Rash Erythematous 45 0.9 0.9 no signal
895 Basal Cell Carcinoma 15 0.9 0.9 no signal
896 Amenorrhoea 16 0.9 0.9 no signal
897 Electrolyte Imbalance 11 0.9 0.9 no signal
898 Incontinence 10 0.9 0.9 no signal
899 Ear Infection 25 0.9 0.9 no signal
900 Dyskinesia 38 0.9 0.9 no signal
901 Intraocular Pressure Increased 12 0.9 0.9 no signal
902 Eczema 47 0.9 0.9 no signal
903 Panic Attack 34 0.9 0.9 no signal
904 Heart Rate Increased 92 0.9 0.9 no signal
905 Cholecystitis 11 0.9 0.9 no signal
906 Product Use In Unapproved Indication 225 0.9 0.9 no signal
907 Haemorrhage 96 0.9 0.9 no signal
908 Coeliac Disease 9 0.9 0.9 no signal
909 Vaginal Haemorrhage 39 0.9 0.9 no signal
910 Bedridden 12 0.9 0.9 no signal
911 Middle Insomnia 17 0.9 0.9 no signal
912 Disability 18 0.9 0.9 no signal
913 Haematochezia 50 0.9 0.9 no signal
914 Hallucination 68 0.9 0.9 no signal
915 Body Temperature Decreased 9 0.9 0.9 no signal
916 Hypotonia 9 0.9 0.9 no signal
917 Small Intestinal Obstruction 11 0.9 0.9 no signal
918 Gastroenteritis 13 0.9 0.9 no signal
919 Product Dose Omission 59 0.9 0.9 no signal
920 Gout 16 0.9 0.9 no signal
921 Blood Glucose Increased 168 0.9 0.9 no signal
922 Impaired Work Ability 19 0.9 0.9 no signal
923 Eyelid Ptosis 9 0.9 0.9 no signal
924 Hypotension 177 0.9 0.9 no signal
925 Toxicity To Various Agents 148 0.9 0.9 no signal
926 Dermatitis Contact 10 0.9 0.9 no signal
927 Clostridium Difficile Infection 19 0.9 0.9 no signal
928 Skin Irritation 40 0.9 0.9 no signal
929 Lung Neoplasm Malignant 36 0.9 0.9 no signal
930 Fungal Infection 29 0.9 0.9 no signal
931 Delirium 30 0.9 0.9 no signal
932 Erectile Dysfunction 22 0.8 0.8 no signal
933 Lymphoma 13 0.8 0.8 no signal
934 Cardiac Failure Congestive 68 0.8 0.8 no signal
935 Skin Cancer 18 0.8 0.8 no signal
936 Upper Gastrointestinal Haemorrhage 14 0.8 0.8 no signal
937 Myelodysplastic Syndrome 12 0.8 0.8 no signal
938 Loss Of Personal Independence In Daily Activities 39 0.8 0.8 no signal
939 Drug Hypersensitivity 159 0.8 0.8 no signal
940 Malnutrition 9 0.8 0.8 no signal
941 Insurance Issue 12 0.8 0.8 no signal
942 Eye Infection 9 0.8 0.8 no signal
943 Abnormal Behaviour 32 0.8 0.8 no signal
944 Diabetic Ketoacidosis 19 0.8 0.8 no signal
945 Cholecystectomy 9 0.8 0.8 no signal
946 Mental Status Changes 22 0.8 0.8 no signal
947 Shock 18 0.8 0.8 no signal
948 Cerebrovascular Accident 134 0.8 0.8 no signal
949 Drug Effect Less Than Expected 11 0.8 0.8 no signal
950 Therapeutic Product Effect Incomplete 55 0.8 0.8 no signal
951 Gastric Disorder 27 0.8 0.8 no signal
952 Knee Arthroplasty 16 0.8 0.8 no signal
953 Loss Of Consciousness 98 0.8 0.7 no signal
954 Injury 54 0.8 0.8 no signal
955 Therapeutic Response Decreased 46 0.7 0.7 no signal
956 Rash Generalised 20 0.7 0.7 no signal
957 Muscle Rigidity 9 0.7 0.7 no signal
958 Appendicitis 7 0.7 0.7 no signal
959 Sudden Death 8 0.7 0.7 no signal
960 Leukaemia 7 0.7 0.7 no signal
961 Back Injury 8 0.7 0.7 no signal
962 Wound Infection 8 0.7 0.7 no signal
963 Product Dispensing Error 16 0.7 0.7 no signal
964 Withdrawal Syndrome 31 0.7 0.7 no signal
965 Asthma 82 0.7 0.7 no signal
966 Intentional Dose Omission 20 0.7 0.7 no signal
967 Mania 12 0.7 0.7 no signal
968 Toxic Epidermal Necrolysis 11 0.7 0.7 no signal
969 Pruritus Generalised 16 0.7 0.7 no signal
970 Intentional Product Use Issue 64 0.7 0.7 no signal
971 Therapy Change 7 0.7 0.7 no signal
972 Melaena 16 0.7 0.7 no signal
973 Affect Lability 7 0.7 0.7 no signal
974 Coagulopathy 12 0.7 0.7 no signal
975 Abnormal Weight Gain 9 0.7 0.7 no signal
976 Road Traffic Accident 30 0.7 0.7 no signal
977 Incorrect Route Of Product Administration 12 0.7 0.7 no signal
978 Kidney Infection 14 0.7 0.7 no signal
979 Poisoning 9 0.7 0.7 no signal
980 Brain Oedema 9 0.7 0.7 no signal
981 Impaired Gastric Emptying 9 0.7 0.7 no signal
982 Bladder Disorder 7 0.7 0.7 no signal
983 Product Physical Issue 14 0.7 0.7 no signal
984 Angioedema 31 0.7 0.7 no signal
985 Respiratory Disorder 21 0.7 0.7 no signal
986 Drug Ineffective 909 0.7 0.7 no signal
987 Post Procedural Haemorrhage 8 0.7 0.7 no signal
988 Depressed Level Of Consciousness 27 0.7 0.7 no signal
989 Adverse Event 63 0.7 0.7 no signal
990 Eyelid Oedema 8 0.7 0.7 no signal
991 Sensory Disturbance 11 0.7 0.7 no signal
992 Drug Ineffective For Unapproved Indication 38 0.7 0.7 no signal
993 Sopor 9 0.7 0.7 no signal
994 Transfusion 7 0.7 0.7 no signal
995 Staphylococcal Infection 22 0.7 0.7 no signal
996 Device Leakage 28 0.6 0.6 no signal
997 Spinal Operation 8 0.6 0.6 no signal
998 Unevaluable Event 50 0.6 0.6 no signal
999 International Normalised Ratio Increased 19 0.6 0.6 no signal
1000 Hepatic Cancer 16 0.6 0.6 no signal
1001 Hip Arthroplasty 10 0.6 0.6 no signal
1002 Accidental Overdose 24 0.6 0.6 no signal
1003 Therapeutic Product Effect Decreased 29 0.6 0.6 no signal
1004 Coronary Artery Occlusion 9 0.6 0.6 no signal
1005 Therapy Non-responder 29 0.6 0.6 no signal
1006 Renal Failure Acute 28 0.6 0.6 no signal
1007 No Therapeutic Response 8 0.6 0.6 no signal
1008 Flushing 66 0.6 0.6 no signal
1009 Abasia 16 0.6 0.6 no signal
1010 Disseminated Intravascular Coagulation 9 0.6 0.6 no signal
1011 Device Breakage 25 0.6 0.6 no signal
1012 Eye Inflammation 6 0.6 0.6 no signal
1013 Dialysis 9 0.6 0.6 no signal
1014 Eosinophilia 11 0.6 0.6 no signal
1015 Nephropathy Toxic 7 0.6 0.6 no signal
1016 Feeling Jittery 12 0.6 0.6 no signal
1017 Infusion Site Pain 8 0.6 0.6 no signal
1018 Blood Glucose Decreased 30 0.6 0.6 no signal
1019 Fistula 7 0.6 0.6 no signal
1020 Sinus Bradycardia 6 0.6 0.6 no signal
1021 Exposure Via Skin Contact 14 0.6 0.6 no signal
1022 Mental Impairment 15 0.6 0.6 no signal
1023 Respiratory Tract Infection 16 0.6 0.6 no signal
1024 Underdose 45 0.6 0.6 no signal
1025 Intentional Drug Misuse 13 0.6 0.6 no signal
1026 Intentional Overdose 39 0.6 0.6 no signal
1027 Generalised Tonic-clonic Seizure 10 0.6 0.6 no signal
1028 Dementia 17 0.6 0.6 no signal
1029 Skin Burning Sensation 43 0.6 0.6 no signal
1030 Multiple Fractures 10 0.6 0.6 no signal
1031 Death 519 0.6 0.6 no signal
1032 Pericarditis 10 0.6 0.6 no signal
1033 Agitation 44 0.6 0.6 no signal
1034 Psoriatic Arthropathy 24 0.6 0.6 no signal
1035 Cardiac Disorder 56 0.6 0.6 no signal
1036 Agranulocytosis 11 0.6 0.6 no signal
1037 Type 2 Diabetes Mellitus 20 0.6 0.6 no signal
1038 Application Site Pain 13 0.6 0.6 no signal
1039 Plasma Cell Myeloma 23 0.6 0.6 no signal
1040 Cerebral Haemorrhage 21 0.6 0.6 no signal
1041 Poor Quality Product Administered 6 0.6 0.6 no signal
1042 Drug Level Decreased 6 0.6 0.6 no signal
1043 Adrenal Insufficiency 7 0.6 0.6 no signal
1044 Gastrointestinal Haemorrhage 49 0.6 0.6 no signal
1045 Injection Site Discomfort 6 0.6 0.6 no signal
1046 Septic Shock 25 0.6 0.6 no signal
1047 Pharyngeal Oedema 9 0.6 0.6 no signal
1048 Hereditary Angioedema 6 0.6 0.6 no signal
1049 Hospitalisation 87 0.6 0.6 no signal
1050 Contraindicated Product Administered 17 0.6 0.6 no signal
1051 Rheumatoid Arthritis 63 0.5 0.5 no signal
1052 Treatment Noncompliance 30 0.5 0.5 no signal
1053 Pulmonary Arterial Hypertension 8 0.5 0.5 no signal
1054 Mydriasis 7 0.5 0.5 no signal
1055 Injection Site Haematoma 8 0.5 0.5 no signal
1056 Conjunctivitis 10 0.5 0.5 no signal
1057 Drug Abuse 45 0.5 0.5 no signal
1058 Erythema Multiforme 5 0.5 0.5 no signal
1059 Treatment Failure 44 0.5 0.5 no signal
1060 Colon Cancer 8 0.5 0.5 no signal
1061 Psoriasis 70 0.5 0.5 no signal
1062 Hepatic Encephalopathy 5 0.5 0.5 no signal
1063 Drug Dose Omission By Device 41 0.5 0.5 no signal
1064 Intestinal Perforation 6 0.5 0.5 no signal
1065 Deformity 5 0.5 0.5 no signal
1066 Encephalopathy 13 0.5 0.5 no signal
1067 Sputum Discoloured 5 0.5 0.5 no signal
1068 Acne 40 0.5 0.5 no signal
1069 Cardiac Arrest 43 0.5 0.5 no signal
1070 Tachypnoea 7 0.5 0.5 no signal
1071 Delusion 8 0.5 0.5 no signal
1072 Parkinsonism 5 0.5 0.5 no signal
1073 Cardiovascular Disorder 13 0.5 0.5 no signal
1074 Myocardial Infarction 89 0.5 0.5 no signal
1075 Wrong Technique In Device Usage Process 23 0.5 0.5 no signal
1076 Activities Of Daily Living Impaired 10 0.5 0.5 no signal
1077 Thyroid Cancer 6 0.5 0.5 no signal
1078 Suicide Attempt 30 0.5 0.5 no signal
1079 Incorrect Dose Administered 111 0.5 0.5 no signal
1080 Rash Papular 11 0.5 0.5 no signal
1081 Hyperbilirubinaemia 5 0.5 0.5 no signal
1082 Infusion Related Reaction 32 0.5 0.5 no signal
1083 Folliculitis 5 0.5 0.5 no signal
1084 Expired Product Administered 16 0.5 0.5 no signal
1085 Dermatitis Atopic 24 0.5 0.5 no signal
1086 Circumstance Or Information Capable Of Leading To Medication Error 16 0.5 0.5 no signal
1087 Fluid Overload 7 0.5 0.5 no signal
1088 Drug Dose Omission 79 0.5 0.5 no signal
1089 Injection Site Induration 6 0.5 0.5 no signal
1090 Device Failure 7 0.5 0.5 no signal
1091 Drug Effect Incomplete 17 0.5 0.5 no signal
1092 Laryngitis 5 0.5 0.5 no signal
1093 Product Quality Issue 62 0.5 0.5 no signal
1094 Economic Problem 7 0.4 0.4 no signal
1095 Extra Dose Administered 18 0.4 0.4 no signal
1096 Lung Infection 7 0.4 0.4 no signal
1097 Synovitis 8 0.4 0.4 no signal
1098 Internal Haemorrhage 5 0.4 0.4 no signal
1099 Product Preparation Error 9 0.4 0.4 no signal
1100 Incorrect Dose Administered By Device 11 0.4 0.4 no signal
1101 Device Defective 7 0.4 0.4 no signal
1102 Sedation 11 0.4 0.4 no signal
1103 Tardive Dyskinesia 12 0.4 0.4 no signal
1104 Psychomotor Hyperactivity 7 0.4 0.4 no signal
1105 Subdural Haematoma 6 0.4 0.4 no signal
1106 Device Use Error 14 0.4 0.4 no signal
1107 Therapeutic Response Shortened 13 0.4 0.4 no signal
1108 Injection Site Mass 15 0.4 0.4 no signal
1109 Multiple Sclerosis Relapse 28 0.4 0.4 no signal
1110 Injection Site Discolouration 5 0.4 0.4 no signal
1111 Injection Site Extravasation 5 0.4 0.4 no signal
1112 Multi-organ Failure 7 0.4 0.4 no signal
1113 Aggression 20 0.4 0.4 no signal
1114 Multiple Sclerosis 19 0.4 0.4 no signal
1115 Drug Reaction With Eosinophilia And Systemic Symptoms 10 0.4 0.4 no signal
1116 Anaphylactic Shock 10 0.4 0.4 no signal
1117 Euphoric Mood 4 0.4 0.4 no signal
1118 Drug Dispensing Error 6 0.4 0.4 no signal
1119 Needle Issue 11 0.4 0.4 no signal
1120 Device Delivery System Issue 10 0.4 0.4 no signal
1121 Pancreatitis 20 0.4 0.4 no signal
1122 Psychotic Disorder 11 0.4 0.4 no signal
1123 Injection Site Swelling 27 0.4 0.3 no signal
1124 Injection Site Pain 108 0.3 0.3 no signal
1125 Wrong Technique In Drug Usage Process 13 0.3 0.3 no signal
1126 Overdose 76 0.3 0.3 no signal
1127 Bronchospasm 5 0.3 0.3 no signal
1128 Gastric Haemorrhage 4 0.3 0.3 no signal
1129 Wrong Technique In Product Usage Process 68 0.3 0.3 no signal
1130 Accident 4 0.3 0.3 no signal
1131 Injection Site Reaction 23 0.3 0.3 no signal
1132 Injection Site Bruising 26 0.3 0.3 no signal
1133 Respiratory Depression 4 0.3 0.3 no signal
1134 Device Issue 28 0.3 0.3 no signal
1135 Personality Change 3 0.3 0.3 no signal
1136 Laceration 3 0.3 0.3 no signal
1137 Device Malfunction 21 0.3 0.3 no signal
1138 Hand Deformity 4 0.3 0.3 no signal
1139 Inappropriate Schedule Of Drug Administration 22 0.3 0.3 no signal
1140 Complication Associated With Device 4 0.3 0.3 no signal
1141 Prescribed Underdose 6 0.3 0.3 no signal
1142 Product Storage Error 26 0.3 0.3 no signal
1143 Pneumocystis Jirovecii Pneumonia 3 0.3 0.3 no signal
1144 Incorrect Product Storage 4 0.3 0.3 no signal
1145 Injury Associated With Device 6 0.3 0.3 no signal
1146 Injection Site Rash 9 0.3 0.3 no signal
1147 Helicobacter Infection 3 0.3 0.3 no signal
1148 Colitis Ulcerative 13 0.3 0.3 no signal
1149 Device Use Issue 5 0.3 0.3 no signal
1150 Device Occlusion 4 0.3 0.3 no signal
1151 Product Complaint 7 0.3 0.3 no signal
1152 Injection Site Haemorrhage 22 0.3 0.3 no signal
1153 Drug Effect Decreased 15 0.3 0.3 no signal
1154 Bipolar Disorder 3 0.3 0.3 no signal
1155 Injection Site Pruritus 18 0.3 0.3 no signal
1156 Status Epilepticus 3 0.3 0.3 no signal
1157 Accidental Exposure To Product 26 0.3 0.3 no signal
1158 Drug Prescribing Error 5 0.3 0.3 no signal
1159 Incorrect Product Administration Duration 5 0.2 0.2 no signal
1160 Injection Site Warmth 5 0.2 0.2 no signal
1161 Muscle Spasticity 3 0.2 0.2 no signal
1162 Peritonitis 5 0.2 0.2 no signal
1163 Extrapyramidal Disorder 6 0.2 0.2 no signal
1164 Injection Site Irritation 3 0.2 0.2 no signal
1165 Ankylosing Spondylitis 3 0.2 0.2 no signal
1166 Drug Administration Error 7 0.2 0.2 no signal
1167 Product Administered At Inappropriate Site 4 0.2 0.2 no signal
1168 Application Site Rash 3 0.2 0.2 no signal
1169 Drug Toxicity 3 0.2 0.2 no signal
1170 Injection Site Urticaria 5 0.2 0.2 no signal
1171 Accidental Underdose 3 0.2 0.2 no signal
1172 No Adverse Event 36 0.2 0.2 no signal
1173 Gastric Cancer 5 0.2 0.2 no signal
1174 Injection Site Erythema 24 0.2 0.2 no signal
1175 Gynaecomastia 6 0.2 0.2 no signal
1176 Drug Withdrawal Syndrome 17 0.2 0.2 no signal
1177 Application Site Erythema 5 0.2 0.2 no signal
1178 Incorrect Drug Administration Duration 5 0.2 0.2 no signal
1179 Pancreatic Carcinoma 5 0.2 0.2 no signal
1180 Bladder Cancer 10 0.2 0.2 no signal
1181 Device Dislocation 7 0.2 0.2 no signal
1182 Menorrhagia 3 0.1 0.1 no signal
1183 Renal Cancer 7 0.1 0.1 no signal
1184 Incorrect Route Of Drug Administration 5 0.1 0.1 no signal
1185 Drug Effective For Unapproved Indication 4 0.1 0.1 no signal
1186 Device Difficult To Use 9 0.1 0.1 no signal
1187 Completed Suicide 11 0.1 0.1 no signal
1188 Product Adhesion Issue 4 0.1 0.1 no signal
1189 Colorectal Cancer 4 0.1 0.1 no signal
1190 Drug Dependence 11 0.1 0.1 no signal