Reaction

Metastases To Spine reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,308 reports · 129 co-occurring drugs

As of the last recalculation, Metastases To Spine appears in 3,308 FAERS reports alongside 129 co-occurring drug terms. The strongest observed disproportionality signal is RIBOCICLIB (PRR 75.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ribociclib	342	75.9	76.8
Fulvestrant	310	65.0	65.7
Goserelin	127	61.9	62.4
Exemestane	153	47.1	47.4
Anastrozole Tablets	147	45.1	45.4
Letrozole	376	43.2	43.5
Anastrozole	207	37.8	38.0
Letrozole Tablets	237	33.3	33.5
Ado-Trastuzumab Emtansine	37	27.9	28.0
Zoledronic Acid	167	27.5	27.6
Bicalutamide	65	27.4	27.5
Everolimus	187	24.4	24.5
Chlorhexidine Gluconate	33	22.9	23.0
Lapatinib	52	21.4	21.5
Erlotinib	32	21.0	21.0
Everolimus Tablets	55	21.0	21.0
Abiraterone	42	19.6	19.7
Octreotide Acetate	92	19.4	19.5
Gefitinib	24	16.8	16.9
Erlotinib Hydrochloride	33	16.7	16.8
Alpelisib	23	16.7	16.8
Sorafenib	52	16.0	16.0
Capecitabine	215	15.7	15.8
Dexamethasone Sodium Phosphate	23	14.3	14.4
Pazopanib Hydrochloride	60	14.2	14.2
Lanreotide Acetate	17	13.7	13.7
Abiraterone Acetate	84	13.2	13.2
Trastuzumab	136	13.0	13.0
Leuprolide Acetate	151	12.8	12.8
Docetaxel Anhydrous	129	12.5	12.5
Docetaxel	129	12.5	12.5
Osimertinib	62	12.4	12.4
Methadone Hydrochloride	21	12.3	12.3
Temozolomide	40	12.1	12.1
Palbociclib	154	10.6	10.6
Pertuzumab	45	10.5	10.6
Magnesium Hydroxide	22	10.3	10.3
Enzalutamide	94	10.3	10.3
Lutetium Lu 177 Vipivotide Tetraxetan	21	10.1	10.1
Cabozantinib	70	9.3	9.4
Morphine	101	8.8	8.8
Dabrafenib	29	8.7	8.7
Paclitaxel	131	8.6	8.6
Gemcitabine	52	8.4	8.4
Paclitaxel (Aibumin-Bound)	104	8.2	8.2
Denosumab	246	8.2	8.2
Regorafenib	15	8.2	8.2
Fam-Trastuzumab Deruxtecan-Nxki	13	8.1	8.2
Docusate Sodium - Sennosides	41	8.1	8.1
Olaparib	26	7.9	7.9
Trametinib	29	7.6	7.6
Granisetron Hydrochloride	12	7.3	7.3
Standardized Senna Concentrate	14	7.0	7.0
Relugolix	26	7.0	7.0
Diphenoxylate Hydrochloride And Atropine Sulfate	15	6.9	6.9
Gemcitabine Hydrochloride	57	6.9	6.9
Clindamycin Phosphate	36	6.8	6.9
Durvalumab	22	6.8	6.8
Cephalexin	23	6.7	6.7
Bevacizumab	128	6.7	6.7
Clindamycin	30	6.7	6.7
Irinotecan Hydrochloride	13	6.4	6.4
Carboplatin	124	6.3	6.3
Docusate Sodium	57	6.3	6.3
Loperamide Hydrochloride Oral	10	6.2	6.2
Meperidine Hydrochloride	9	6.2	6.2
Fexofenadine Hcl	9	6.1	6.1
Granisetron	10	6.0	6.0
Abemaciclib	18	5.7	5.7
Methadone	38	5.6	5.6
Dronabinol	7	5.5	5.5
Ibuprofen And Diphenhydramine Citrate	20	5.4	5.4
Doxorubicin Hydrochloride	28	5.4	5.4
Apalutamide	10	5.4	5.4
Ampicillin	7	5.3	5.3
Ampicillin Sodium	7	5.3	5.3
Cannabidiol	19	5.1	5.1
Ketoconazole Foam	12	5.1	5.1
Ketoconazole	14	5.1	5.1
Ketoconazole Cream, 2%	12	5.1	5.1
Prochlorperazine	22	5.0	5.0
Tolterodine Tartrate	7	4.9	4.9
Loperamide Hcl	10	4.9	4.9
Doxorubicin	68	4.9	4.9
Prochlorperazine Maleate	7	4.8	4.8
Hydromorphone Hydrochloride	67	4.7	4.7
Valganciclovir Hydrochloride Powder,	9	4.7	4.7
Fluorouracil Cream, 0.5%	54	4.5	4.5
Nivolumab	68	4.5	4.5
Fluorouracil	54	4.4	4.5
Cetuximab	22	4.4	4.4
Ifosfamide	15	4.4	4.4
Filgrastim	26	4.4	4.4
Metoclopramide Hydrochloride	53	4.4	4.4
Fentanyl	67	4.3	4.4
Enoxaparin Sodium	39	4.3	4.3
Metoclopramide	36	4.2	4.2
Cisplatin	50	4.1	4.1
Imatinib	11	3.9	3.9
Axitinib	12	3.9	3.9
Etoposide	44	3.8	3.8
Morphine Sulfate	71	3.7	3.7
Oxycodone Hydrochloride And Acetaminophen	58	3.7	3.7
Erythropoietin	12	3.7	3.7
Vemurafenib	7	3.7	3.7
Ipilimumab	25	3.7	3.7
Pemetrexed Disodium	22	3.7	3.7
Atezolizumab	22	3.6	3.6
Sunitinib Malate	22	3.5	3.5
Pemetrexed	12	3.5	3.5
Darbepoetin Alfa	29	3.4	3.4
Dexamethasone 1.5 Mg	153	3.4	3.4
Dexamethasone	154	3.4	3.4
Bupivacaine	5	3.4	3.4
Cladribine	5	3.3	3.3
Thalidomide	19	3.3	3.3
Fexofenadine Hydrochloride	11	3.2	3.2
Trifluridine And Tipiracil	5	2.9	2.9
Oxycodone Hydrochloride	97	2.9	2.9
Vismodegib	4	2.8	2.8
Fentanyl Citrate	8	2.8	2.8
Lenvatinib	14	2.7	2.7
Conjugated Estrogens And Medroxyprogesterone Acetate	10	2.7	2.7
Encorafenib	4	2.5	2.5
Iohexol	3	2.3	2.3
Alteplase	5	2.1	2.1
Acalabrutinib	4	2.1	2.1
Crizotinib	4	2.0	2.0
Pegfilgrastim	27	1.7	1.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.