OpenPV Signal Explorer
FAERS disproportionality dashboard
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Which drugs are most reported with Progressive multifocal leukoencephalopathy?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,144 reports · 225 co-occurring drugs

As of the last recalculation, Progressive Multifocal Leukoencephalopathy appears in 8,144 FAERS reports alongside 225 co-occurring drug terms. The strongest observed disproportionality signal is BENDAMUSTINE HCL (PRR 55.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Bendamustine Hcl32155.056.2
Natalizumab2,12740.140.6
Fludarabine Phosphate52436.336.8
Bendamustine Hydrochloride12827.728.0
Rituximab1,79727.627.8
Alemtuzumab19326.126.4
Busulfan14624.124.3
Cyclophosphamide Injection, Solution1,21620.520.6
Cyclophosphamide1,21620.520.6
Cyclophosphamide For Injection1,21620.520.6
Melphalan17620.220.3
Melphalan Hydrochloride18319.119.2
Brentuximab Vedotin6616.616.7
Abacavir Sulfate6116.116.2
Valganciclovir Hydrochloride Powder,6914.614.7
Thiotepa5314.314.3
Doxorubicin46714.114.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled11313.713.8
Vincristine Sulfate15113.413.5
Methylprednisolone Acetate4012.812.9
Zidovudine6612.712.8
Polatuzumab Vedotin4812.612.7
Mycophenolate Mofetil61112.312.4
Mycophenolate Mofetil Hydrochloride61112.312.4
Oseltamivir3812.212.3
Fingolimod Hcl39512.212.3
Doxorubicin Hydrochloride15312.212.2
Lamivudine Oral11411.711.7
Mycophenilic Acid9311.611.6
Prednisolone74911.611.6
Prednisolone Oral74911.611.6
Prednisolone Oral Solution74911.611.6
Lamivudine13411.311.3
Basiliximab5111.111.2
Obinutuzumab7111.111.2
Tacrolimus Ointment 0.1%48810.610.6
Tacrolimus Extended-Release Capsules48810.610.6
Valganciclovir7710.510.6
Valganciclovir Hydrochloride7710.510.6
Methylprednisolone52710.310.4
Efavirenz4410.110.2
Ifosfamide8410.110.1
Etoposide27910.010.0
Azathioprine3249.79.8
Nevirapine349.79.7
Ritonavir 100 Mg569.69.7
Axicabtagene Ciloleucel379.69.7
Tacrolimus5439.49.5
Darunavir559.49.4
Cetirizine Hydrochloride Allergy1089.29.3
Cetirizine Hydrochloride Tablets1089.29.3
Lopinavir And Ritonavir489.19.1
Cytarabine2038.88.9
Mycophenolic Acid1088.78.8
Ritonavir978.68.6
Raltegravir538.38.3
Esomeprazole Magnesium Capsule, Delayed Release468.18.2
Esomeprazole Magnesium Delayed Release Capsules468.18.2
Esomeprazole Magnesium Dihydrate468.18.1
Bleomycin Sulfate327.98.0
Daratumumab1197.77.7
Filgrastim1087.47.4
Ganciclovir Sodium307.37.3
Mirtazapine2507.27.2
Dexamethasone Sodium Phosphate287.17.1
Thalidomide1007.07.1
Ganciclovir276.86.8
Carfilzomib746.76.8
Sirolimus356.76.7
Atazanavir366.46.4
Vitamin E786.46.4
Cisplatin1775.95.9
Cyclosporine2455.85.8
Dolutegravir Sodium195.45.4
Ofatumumab695.35.4
Tenofovir Disoproxil Fumarate Tablets185.35.3
Belimumab655.35.3
Atovaquone165.15.1
Cladribine195.15.1
Prednisone9065.15.1
Bortezomib1654.84.8
Human Immunoglobulin G384.74.7
Glatiramer Acetate1064.64.6
Hydroxychloroquine1304.54.5
Daspone174.54.5
Dapsone Gel, 5%174.54.5
Everolimus Tablets284.34.3
Methylprednisolone Sodium Succinate764.24.2
Ocrelizumab1004.24.2
Baclofen1384.14.2
Sulfamethoxazole And Trimethoprim1354.14.1
Cetirizine1234.14.1
Azacitidine For294.14.1
Dapsone174.14.1
Imatinib284.14.1
Oseltamivir Phosphate384.04.0
Dexamethasone 1.5 Mg4293.93.9
Dexamethasone4293.83.8
Amantadine233.83.8
Anti-Thymocyte Globulin (Rabbit)123.83.8
Mesna Injection123.73.7
Emtricitabine And Tenofovir Disoproxil Fumarate653.73.7
Modafinil463.73.7
Esomeprazole883.73.7
Mesna123.63.7
Pomalidomide1413.53.6
Methotrexate5403.43.4
Siponimod123.43.4
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate123.43.4
Tizanidine Hydrochloride243.43.4
Methotrexate Sodium6093.43.4
Valacyclovir543.33.3
Carboxymethylcellulose Sodium123.33.3
Azacitidine373.23.2
Nystatin Ointment323.13.1
Nystatin Cream323.13.1
Lansoprazole2103.13.1
Atenolol1573.13.1
Trimethoprim143.03.0
Posaconazole Delayed-Release133.03.0
Nystatin323.03.0
Leucovorin Calcium222.92.9
Ibrutinib922.92.9
Duloxetine792.92.9
Diphenhydramine Hydrochloride1842.92.9
Dimethyl Fumarate1372.92.9
Itraconazole132.82.8
Voriconazole Injection232.72.7
Venetoclax652.72.7
Anti-Itch702.72.7
Anti-Pruritic702.72.7
Antipruritic (Anti-Itch)702.72.7
Cool Relief Gel With Aloe702.72.7
Drs. Hydrocortisone702.72.7
Hydrocortisone Continuous Spray702.72.7
Hydrocortisone Spray702.72.7
Anti-Itch Cream702.72.7
Hydrocortisone Lotion702.72.7
Hydrocortisone Cream 1%702.72.7
Hydrocortisone Cream 1/2%702.72.7
Hydrocortisone 1%702.72.7
Hydrocortisone Cream702.72.7
Valacyclovir Hydrochloride732.72.7
Selinexor92.72.7
Amphotericin B132.72.7
Entecavir122.62.6
Cetiirizine432.62.6
Hydrocortisone902.62.6
Tenofovir Disoproxil Fumarate332.62.6
Diphenhydramine622.52.5
Dalfampridine702.52.5
Carboplatin1222.52.5
Hydrocortisone Acetate702.52.5
Atropine82.52.5
Fluconazole662.42.4
Acyclovir1072.42.4
Duloxetine Hydrochloride1752.42.4
Quinine82.42.4
Atropine Sulfate102.42.4
Posaconazole152.42.4
Sennosides 8.6 Mg Tablets192.32.3
Senna192.32.3
Meclizine Hcl 12.5Mg122.32.3
Meclizine Hcl 25Mg122.32.3
Meclizine Hcl 12.5 Mg122.32.3
Meclizine Hcl 25 Mg122.32.3
Gemcitabine342.22.2
Ezetimibe And Simvastatin132.22.2
Bisacodyl122.22.2
Acetaminophen Tablet Extended Release2142.22.2
Bisacodyl Suppositories112.22.2
Pain Reliever2142.22.2
Acetaminophen 500Mg2142.22.2
Biscodyl112.22.2
Tizanidine202.12.1
Senna Leaf192.12.1
Voriconazole252.12.1
Ixazomib232.02.0
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide82.02.0
Cetirizine Hydrochloride1292.02.0
Oxybutynin232.02.0
Tapentadol Hydrochloride262.02.0
Blinatumomab82.02.0
Acalabrutinib91.91.9
Gemcitabine Hydrochloride391.91.9
Teriflunomide331.91.9
Interferon Beta-1B141.91.9
Levetiracetam In Sodium Chloride561.91.9
Levetiracetam Oral561.91.9
Levetiracetam Injection561.91.9
Levetiracetam931.81.8
Fluorouracil Cream, 0.5%531.81.8
Loratadine Tablet371.81.8
Fluorouracil531.81.8
Oxybutynin Chloride61.81.8
Aripiprazole Oral281.71.7
Aripiprazole Orally Disintegrating281.71.7
Diroximel Fumarate81.71.7
Sofosbuvir131.71.7
Pyrazinamide61.61.6
Letrozole Tablets301.61.6
Leflunomide651.61.6
Emtricitabine And Tenofovir Alafenamide71.61.6
Everolimus311.61.6
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate111.61.6
Lenalidomide2531.51.5
Pregabalin1591.51.5
Granisetron Hydrochloride61.51.5
Tofacitinib Citrate71.41.4
Armodafinil111.31.3
Cabotegravir41.31.3
Interferon Beta-1A951.31.3
Amphetamine41.21.2
Pembrolizumab501.21.2
Temozolomide101.21.2
Docetaxel Anhydrous291.11.1
Docetaxel291.11.1
Ruxolitinib291.01.0
Pegfilgrastim391.01.0
Pemetrexed81.01.0
Etanercept2020.90.9
Peginterferon Beta-1A40.80.8
Abiraterone40.80.8
Osimertinib80.60.6
Durvalumab50.60.6

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.