Drug

Cefepime Hydrochloride

1,097 flagged reaction(s) · 58,039 total co-reports · max PRR 253.6

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Meningitis Candida	11	253.6	253.7	signal
2	Burkholderia Test Positive	18	221.3	221.5	signal
3	Corynebacterium Bacteraemia	11	200.0	200.1	signal
4	Aeromonas Infection	13	104.9	105.0	signal
5	Hepatosplenic Candidiasis	10	94.9	95.0	signal
6	Antibiotic Level Above Therapeutic	27	94.7	94.9	signal
7	Cutaneous Mucormycosis	12	94.5	94.5	signal
8	Trichosporon Infection	25	88.2	88.3	signal
9	Uraemic Encephalopathy	16	71.5	71.5	signal
10	Hyperoxaluria	9	71.3	71.3	signal
11	Phrenic Nerve Paralysis	11	70.0	70.0	signal
12	Laryngeal Inflammation	9	66.0	66.0	signal
13	Nail Bed Inflammation	15	64.8	64.8	signal
14	Geotrichum Infection	10	64.5	64.6	signal
15	Cns Ventriculitis	15	62.9	62.9	signal
16	Engraft Failure	13	62.4	62.4	signal
17	Septic Embolus	37	60.8	60.9	signal
18	Disseminated Mucormycosis	15	52.6	52.7	signal
19	Fungaemia	59	51.3	51.5	signal
20	Enterococcal Bacteraemia	39	50.2	50.3	signal
21	Cerebral Aspergillosis	22	48.6	48.7	signal
22	Vancomycin Infusion Reaction	13	48.5	48.5	signal
23	Nephritis Allergic	14	48.3	48.4	signal
24	Eye Infection Fungal	13	46.5	46.5	signal
25	Stenotrophomonas Infection	42	42.4	42.5	signal
26	Pneumonia Necrotising	20	42.0	42.1	signal
27	Enterobacter Bacteraemia	9	40.2	40.2	signal
28	Corynebacterium Infection	15	37.9	37.9	signal
29	Cytomegalovirus Enterocolitis	21	37.1	37.1	signal
30	Engraftment Syndrome	16	36.6	36.7	signal
31	Ureaplasma Infection	11	36.6	36.6	signal
32	Blastomycosis	13	36.5	36.5	signal
33	Differentiation Syndrome	19	35.7	35.7	signal
34	Cytokine Storm	18	35.5	35.6	signal
35	Methaemoglobinaemia	60	35.0	35.2	signal
36	Crystalluria	14	34.4	34.4	signal
37	Glomerulosclerosis	16	34.0	34.0	signal
38	Dysbiosis	20	33.5	33.5	signal
39	Neutropenic Colitis	50	32.5	32.6	signal
40	Nasal Mucosal Disorder	14	32.1	32.1	signal
41	Fusarium Infection	16	31.3	31.4	signal
42	Disseminated Cryptococcosis	17	31.0	31.0	signal
43	Enterococcus Test Positive	15	30.8	30.8	signal
44	Malacoplakia	9	30.7	30.8	signal
45	Mucormycosis	59	30.7	30.8	signal
46	Encephalopathy	560	30.6	31.7	signal
47	Cytomegalovirus Test Positive	40	30.2	30.3	signal
48	Acute Generalised Exanthematous Pustulosis	173	29.9	30.2	signal
49	Ecthyma	9	29.9	29.9	signal
50	Pseudomonal Sepsis	39	29.6	29.7	signal
51	Enterococcal Sepsis	18	29.5	29.5	signal
52	Urinary Tract Infection Pseudomonal	13	29.4	29.5	signal
53	Sputum Culture Positive	18	29.2	29.2	signal
54	Procalcitonin Increased	25	29.0	29.0	signal
55	Pseudomonal Bacteraemia	18	28.7	28.7	signal
56	Pulmonary Mucormycosis	11	28.5	28.5	signal
57	Enterococcal Infection	103	28.4	28.6	signal
58	Bacillus Infection	13	27.8	27.8	signal
59	Mediastinitis	12	27.6	27.6	signal
60	Necrotising Retinitis	13	27.2	27.2	signal
61	Toxic Encephalopathy	100	27.1	27.2	signal
62	Cholestatic Liver Injury	43	26.8	26.9	signal
63	Botulism	14	26.6	26.6	signal
64	Caecitis	9	26.3	26.4	signal
65	Enterobacter Infection	33	26.2	26.3	signal
66	Pneumonia Pseudomonal	29	25.4	25.5	signal
67	Red Man Syndrome	17	25.4	25.5	signal
68	Acute Myeloid Leukaemia Recurrent	40	25.0	25.1	signal
69	Systemic Candida	46	24.8	24.9	signal
70	Sjs-ten Overlap	12	24.7	24.7	signal
71	Retinal Ischaemia	11	24.5	24.5	signal
72	Neurotoxicity	319	24.5	24.9	signal
73	Klebsiella Infection	92	24.4	24.5	signal
74	Diffuse Alveolar Damage	21	24.2	24.3	signal
75	Pseudomonas Test Positive	15	24.2	24.3	signal
76	Linear Iga Disease	30	24.0	24.1	signal
77	Systemic Mycosis	21	24.0	24.0	signal
78	Abdominal Compartment Syndrome	11	23.5	23.5	signal
79	Acinetobacter Infection	19	23.4	23.4	signal
80	Immune Effector Cell-associated Neurotoxicity Syndrome	98	23.2	23.4	signal
81	Blood Culture Positive	52	22.8	22.9	signal
82	Mitochondrial Toxicity	14	22.6	22.7	signal
83	Metabolic Encephalopathy	51	22.6	22.7	signal
84	Klebsiella Test Positive	11	22.4	22.4	signal
85	Sputum Abnormal	11	22.4	22.4	signal
86	Clostridium Difficile Colitis	177	22.2	22.4	signal
87	Cytokine Release Syndrome	315	22.0	22.4	signal
88	Diaphragmatic Paralysis	10	22.0	22.0	signal
89	Symmetrical Drug-related Intertriginous And Flexural Exanthema	13	21.8	21.8	signal
90	Klebsiella Bacteraemia	15	21.4	21.5	signal
91	Meningitis Bacterial	23	21.3	21.4	signal
92	Streptococcal Sepsis	19	21.2	21.2	signal
93	Brain Herniation	47	20.9	21.0	signal
94	Pseudomonas Infection	133	20.9	21.1	signal
95	Mycobacterium Abscessus Infection	11	20.7	20.7	signal
96	Pseudomembranous Colitis	35	20.7	20.8	signal
97	Rash Morbilliform	43	20.6	20.7	signal
98	Renal Tubular Necrosis	152	20.5	20.7	signal
99	Status Epilepticus	174	20.4	20.6	signal
100	Eosinophilic Pneumonia Acute	13	20.0	20.0	signal
101	Drug Reaction With Eosinophilia And Systemic Symptoms	379	19.7	20.2	signal
102	Staphylococcus Test Positive	31	19.4	19.4	signal
103	Pneumonia Fungal	56	19.2	19.2	signal
104	Bronchopulmonary Aspergillosis	111	19.1	19.2	signal
105	Subcutaneous Emphysema	14	18.9	18.9	signal
106	Tracheobronchitis	11	18.9	18.9	signal
107	Mixed Liver Injury	41	18.7	18.7	signal
108	Escherichia Bacteraemia	32	18.4	18.4	signal
109	Clostridium Test Positive	30	18.2	18.3	signal
110	Respiratory Alkalosis	22	18.0	18.1	signal
111	Pathogen Resistance	123	17.9	18.1	signal
112	Serratia Infection	10	17.9	17.9	signal
113	Culture Urine Positive	19	17.8	17.8	signal
114	Bacteraemia	158	17.8	18.0	signal
115	Candida Sepsis	12	17.7	17.7	signal
116	Cytomegalovirus Viraemia	58	17.6	17.6	signal
117	Febrile Neutropenia	877	17.6	18.5	signal
118	Myoclonus	157	17.5	17.6	signal
119	Continuous Haemodiafiltration	13	17.4	17.4	signal
120	Venoocclusive Liver Disease	64	17.2	17.3	signal
121	Strongyloidiasis	21	17.2	17.2	signal
122	Diffuse Large B-cell Lymphoma Refractory	12	17.1	17.1	signal
123	Hypercapnia	38	16.8	16.9	signal
124	Sinusitis Fungal	10	16.8	16.8	signal
125	Acute Graft Versus Host Disease In Skin	35	16.8	16.8	signal
126	Multiple Organ Dysfunction Syndrome	352	16.7	17.1	signal
127	Jarisch-herxheimer Reaction	9	16.7	16.7	signal
128	Immune Thrombocytopenia	56	16.6	16.6	signal
129	Aspergillus Infection	81	16.5	16.6	signal
130	Pneumonia Klebsiella	22	15.9	15.9	signal
131	Pneumonia Cytomegaloviral	23	15.9	15.9	signal
132	Vascular Device Infection	54	15.8	15.9	signal
133	Fungal Sepsis	10	15.8	15.8	signal
134	Septic Shock	507	15.5	16.0	signal
135	Catheter Related Infection	12	15.5	15.5	signal
136	Intracranial Mass	11	15.5	15.5	signal
137	Pneumonia Staphylococcal	23	15.4	15.5	signal
138	Large Intestine Infection	14	15.4	15.4	signal
139	Slow Response To Stimuli	15	15.4	15.4	signal
140	Device Related Sepsis	23	15.0	15.0	signal
141	Nephropathy Toxic	125	14.8	15.0	signal
142	Pneumomediastinum	20	14.8	14.8	signal
143	Hypertensive Heart Disease	21	14.8	14.8	signal
144	Electrocardiogram T Wave Abnormal	17	14.5	14.5	signal
145	Nocardiosis	28	14.5	14.5	signal
146	Histoplasmosis Disseminated	17	14.4	14.4	signal
147	Staphylococcal Bacteraemia	47	14.3	14.4	signal
148	Alpha Haemolytic Streptococcal Infection	10	14.2	14.2	signal
149	Product Ineffective For Unapproved Use	15	14.2	14.2	signal
150	Acute Graft Versus Host Disease In Intestine	15	14.1	14.1	signal
151	Haemophagocytic Lymphohistiocytosis	77	14.1	14.2	signal
152	Urinary Tract Infection Enterococcal	10	14.0	14.1	signal
153	Cerebral Artery Embolism	13	14.0	14.0	signal
154	Infectious Pleural Effusion	16	14.0	14.0	signal
155	Acute Respiratory Distress Syndrome	186	13.9	14.1	signal
156	Blast Cell Count Increased	11	13.8	13.8	signal
157	Acute Lymphocytic Leukaemia Recurrent	27	13.8	13.8	signal
158	Hyporesponsive To Stimuli	12	13.8	13.8	signal
159	Pneumocystis Jirovecii Infection	12	13.8	13.8	signal
160	Mental Status Changes	288	13.7	13.9	signal
161	Clostridial Infection	35	13.5	13.6	signal
162	Eosinophilic Pneumonia	32	13.5	13.6	signal
163	Streptococcal Bacteraemia	11	13.5	13.5	signal
164	Epidermal Necrosis	10	13.5	13.5	signal
165	Systemic Inflammatory Response Syndrome	38	13.2	13.2	signal
166	Autoimmune Haemolytic Anaemia	34	13.2	13.2	signal
167	Vanishing Bile Duct Syndrome	11	13.1	13.1	signal
168	Brain Abscess	25	13.1	13.1	signal
169	Tubulointerstitial Nephritis	185	13.1	13.2	signal
170	Henoch-schonlein Purpura	21	12.8	12.8	signal
171	Ischaemic Hepatitis	13	12.7	12.7	signal
172	Lung Consolidation	27	12.7	12.7	signal
173	Acute Respiratory Failure	181	12.5	12.6	signal
174	Haemodynamic Instability	70	12.3	12.4	signal
175	Haemophilus Infection	9	12.2	12.2	signal
176	Retroperitoneal Haematoma	20	12.0	12.0	signal
177	Disseminated Intravascular Coagulation	128	12.0	12.1	signal
178	Perirectal Abscess	10	11.8	11.8	signal
179	Blood Fibrinogen Decreased	10	11.8	11.8	signal
180	Kidney Fibrosis	15	11.4	11.5	signal
181	Pulseless Electrical Activity	36	11.4	11.4	signal
182	Haemodialysis	73	11.3	11.4	signal
183	Eosinophilia	150	11.3	11.4	signal
184	Nephritis Interstitial	11	11.3	11.3	signal
185	Multiple-drug Resistance	26	11.1	11.1	signal
186	Acute Kidney Injury	1,268	11.0	11.8	signal
187	Capillary Leak Syndrome	17	10.9	10.9	signal
188	Pharyngeal Inflammation	10	10.9	10.9	signal
189	Enterocolitis	47	10.9	10.9	signal
190	Organising Pneumonia	40	10.8	10.8	signal
191	Nosocomial Infection	18	10.7	10.8	signal
192	Tumour Lysis Syndrome	71	10.7	10.8	signal
193	Toxic Epidermal Necrolysis	122	10.7	10.7	signal
194	Candida Infection	134	10.6	10.7	signal
195	Liver Abscess	26	10.6	10.6	signal
196	Hypoxia	281	10.6	10.7	signal
197	Acidosis	61	10.5	10.5	signal
198	Heparin-induced Thrombocytopenia	39	10.4	10.4	signal
199	Staphylococcal Sepsis	39	10.4	10.4	signal
200	Cerebral Ventricle Dilatation	9	10.2	10.2	signal
201	Distributive Shock	17	10.1	10.2	signal
202	Histiocytosis Haematophagic	23	10.1	10.1	signal
203	Drug Resistance	195	10.0	10.1	signal
204	Venoocclusive Disease	19	10.0	10.0	signal
205	Hyperphosphataemia	16	9.9	10.0	signal
206	Escherichia Test Positive	9	9.9	9.9	signal
207	Activated Partial Thromboplastin Time Prolonged	38	9.9	9.9	signal
208	Necrotising Fasciitis	26	9.7	9.7	signal
209	Leukocytosis	133	9.7	9.8	signal
210	Acute Febrile Neutrophilic Dermatosis	17	9.7	9.7	signal
211	Lung Infiltration	64	9.5	9.5	signal
212	Pulmonary Haemorrhage	56	9.4	9.5	signal
213	Drug Clearance Decreased	9	9.4	9.4	signal
214	Acute Graft Versus Host Disease	33	9.4	9.4	signal
215	Aplasia	14	9.2	9.2	signal
216	Hepatosplenomegaly	18	9.2	9.2	signal
217	Splenic Infarction	12	9.1	9.1	signal
218	Pneumonia Viral	22	9.1	9.1	signal
219	Hypernatraemia	34	9.0	9.0	signal
220	Aspergillosis	9	8.9	8.9	signal
221	Multi-organ Failure	119	8.9	9.0	signal
222	Hypersensitivity Vasculitis	18	8.9	8.9	signal
223	Mycobacterium Avium Complex Infection	18	8.9	8.9	signal
224	Electroencephalogram Abnormal	21	8.8	8.8	signal
225	Graft Versus Host Disease	48	8.7	8.8	signal
226	Adenovirus Infection	19	8.7	8.7	signal
227	Atelectasis	64	8.7	8.7	signal
228	Agranulocytosis	122	8.7	8.7	signal
229	Drug Level Increased	109	8.7	8.7	signal
230	Pneumonia Bacterial	60	8.7	8.7	signal
231	Clostridium Difficile Infection	141	8.6	8.6	signal
232	Rash Maculo-papular	143	8.5	8.6	signal
233	Endocarditis	33	8.5	8.5	signal
234	Respiratory Failure	467	8.4	8.6	signal
235	Lobar Pneumonia	12	8.4	8.4	signal
236	Graft Versus Host Disease In Skin	14	8.4	8.4	signal
237	Acute Myeloid Leukaemia	99	8.4	8.4	signal
238	Cholestasis	121	8.3	8.4	signal
239	Cryptococcosis	10	8.2	8.2	signal
240	Cytomegalovirus Colitis	14	8.1	8.1	signal
241	Bacterial Sepsis	20	8.1	8.1	signal
242	Herpes Simplex	39	7.9	7.9	signal
243	Urinary Tract Infection Bacterial	15	7.9	7.9	signal
244	Cystitis Haemorrhagic	24	7.9	7.9	signal
245	Streptococcal Infection	33	7.8	7.8	signal
246	Aplastic Anaemia	31	7.8	7.8	signal
247	Serum Ferritin Increased	31	7.8	7.8	signal
248	Cutaneous Vasculitis	21	7.7	7.7	signal
249	Shock	134	7.7	7.8	signal
250	Dermatitis Exfoliative Generalised	20	7.7	7.7	signal
251	Chorea	10	7.6	7.6	signal
252	Immunosuppressant Drug Level Increased	19	7.6	7.6	signal
253	Pancytopenia	317	7.5	7.6	signal
254	Hypovolaemic Shock	27	7.5	7.5	signal
255	Inhibitory Drug Interaction	9	7.4	7.4	signal
256	Purpura	50	7.4	7.5	signal
257	Acute Lymphocytic Leukaemia	16	7.4	7.4	signal
258	Oliguria	35	7.4	7.4	signal
259	Graft Versus Host Disease In Gastrointestinal Tract	12	7.4	7.4	signal
260	Periodontitis	12	7.4	7.4	signal
261	Diplegia	11	7.3	7.3	signal
262	Empyema	11	7.3	7.3	signal
263	Sepsis	614	7.2	7.5	signal
264	Pneumocystis Jirovecii Pneumonia	55	7.2	7.3	signal
265	Drug Level Above Therapeutic	25	7.2	7.2	signal
266	Brain Death	17	7.2	7.2	signal
267	Hyperbilirubinaemia	56	7.1	7.2	signal
268	Peripheral Ischaemia	22	7.1	7.1	signal
269	Respiratory Distress	147	7.0	7.1	signal
270	Infective Pulmonary Exacerbation Of Cystic Fibrosis	29	7.0	7.0	signal
271	Azotaemia	21	6.9	6.9	signal
272	Blood Ph Decreased	9	6.9	6.9	signal
273	Hypoalbuminaemia	40	6.9	6.9	signal
274	Hyperammonaemia	26	6.8	6.9	signal
275	Abscess Limb	22	6.8	6.8	signal
276	Dermatitis Bullous	37	6.8	6.8	signal
277	Blood Urea Increased	86	6.7	6.7	signal
278	Neutrophil Count Decreased	206	6.7	6.8	signal
279	Kyphosis	9	6.7	6.7	signal
280	Brain Oedema	64	6.7	6.7	signal
281	Pleuritic Pain	14	6.6	6.6	signal
282	Renal Failure Acute	217	6.6	6.7	signal
283	Stevens-johnson Syndrome	111	6.5	6.6	signal
284	Unresponsive To Stimuli	127	6.5	6.5	signal
285	Thrombocytopenia	549	6.5	6.7	signal
286	Immune Thrombocytopenic Purpura	14	6.4	6.4	signal
287	Covid-19 Pneumonia	58	6.4	6.4	signal
288	Staphylococcal Infection	161	6.4	6.4	signal
289	Device Related Infection	75	6.4	6.4	signal
290	Anuria	42	6.4	6.4	signal
291	Thrombotic Microangiopathy	47	6.4	6.4	signal
292	Hypertransaminasaemia	33	6.4	6.4	signal
293	Drug Eruption	85	6.3	6.4	signal
294	Thrombotic Thrombocytopenic Purpura	17	6.3	6.3	signal
295	Intraventricular Haemorrhage	12	6.3	6.3	signal
296	Hyperthermia	36	6.3	6.3	signal
297	Clonus	13	6.2	6.2	signal
298	Tachypnoea	64	6.2	6.2	signal
299	Creatinine Renal Clearance Decreased	19	6.2	6.2	signal
300	Mechanical Ventilation	9	6.2	6.2	signal
301	Hypogammaglobulinaemia	30	6.1	6.2	signal
302	Hepatic Cytolysis	57	6.1	6.1	signal
303	Endotracheal Intubation	13	6.1	6.1	signal
304	Pulmonary Alveolar Haemorrhage	26	6.1	6.1	signal
305	Hepatic Lesion	20	6.1	6.1	signal
306	Drug-induced Liver Injury	142	6.1	6.1	signal
307	Renal Tubular Disorder	13	6.0	6.0	signal
308	Respiratory Acidosis	18	6.0	6.0	signal
309	Osteomyelitis	83	6.0	6.1	signal
310	Hypervolaemia	22	6.0	6.0	signal
311	Gastrointestinal Ulcer	10	5.9	5.9	signal
312	Escherichia Sepsis	13	5.9	5.9	signal
313	Mucosal Inflammation	116	5.8	5.9	signal
314	Stem Cell Transplant	11	5.8	5.8	signal
315	Lactic Acidosis	142	5.8	5.9	signal
316	Wound Dehiscence	15	5.8	5.8	signal
317	Pancreatitis Necrotising	10	5.8	5.8	signal
318	Paronychia	19	5.8	5.8	signal
319	Cardiac Dysfunction	16	5.7	5.8	signal
320	Left Ventricular Dysfunction	29	5.7	5.7	signal
321	Haemolytic Anaemia	39	5.7	5.7	signal
322	Livedo Reticularis	9	5.7	5.7	signal
323	Dialysis	61	5.6	5.7	signal
324	Escherichia Infection	35	5.6	5.6	signal
325	Hypovolaemia	25	5.6	5.6	signal
326	Coagulopathy	71	5.6	5.6	signal
327	Lung Opacity	11	5.6	5.6	signal
328	Aortic Arteriosclerosis	11	5.6	5.6	signal
329	Rash Pustular	31	5.6	5.6	signal
330	Metabolic Acidosis	134	5.6	5.6	signal
331	Neutrophilia	24	5.6	5.6	signal
332	Pneumatosis Intestinalis	12	5.6	5.6	signal
333	Skin Necrosis	22	5.6	5.6	signal
334	Generalised Oedema	52	5.5	5.6	signal
335	Encephalitis	29	5.5	5.5	signal
336	Pulse Absent	20	5.5	5.5	signal
337	Shock Haemorrhagic	34	5.5	5.5	signal
338	Bk Virus Infection	14	5.5	5.5	signal
339	Cerebral Haematoma	14	5.5	5.5	signal
340	Toxic Skin Eruption	42	5.5	5.5	signal
341	Haemolysis	32	5.4	5.4	signal
342	Haemothorax	12	5.4	5.4	signal
343	Cytopenia	49	5.4	5.4	signal
344	Neutropenia	555	5.4	5.5	signal
345	Pleural Effusion	249	5.4	5.4	signal
346	Large Intestinal Ulcer	11	5.3	5.3	signal
347	Neutropenic Sepsis	29	5.3	5.3	signal
348	Oesophageal Candidiasis	16	5.3	5.3	signal
349	Bacterial Test Positive	9	5.3	5.3	signal
350	Sinus Tachycardia	57	5.3	5.3	signal
351	Colitis Ischaemic	27	5.3	5.3	signal
352	Aspartate Aminotransferase Increased	213	5.3	5.3	signal
353	Blood Creatinine Increased	262	5.3	5.3	signal
354	Drug Ineffective For Unapproved Indication	223	5.3	5.3	signal
355	Immune Reconstitution Inflammatory Syndrome	20	5.2	5.3	signal
356	Small Intestinal Obstruction	49	5.2	5.3	signal
357	Cytomegalovirus Infection Reactivation	17	5.2	5.2	signal
358	Neurological Decompensation	9	5.2	5.2	signal
359	Hepatocellular Injury	56	5.2	5.2	signal
360	Candidiasis	16	5.2	5.2	signal
361	Posterior Reversible Encephalopathy Syndrome	37	5.1	5.1	signal
362	Bacterial Infection	72	5.1	5.1	signal
363	Blood Bilirubin Increased	105	5.1	5.1	signal
364	Atrial Flutter	31	5.1	5.1	signal
365	Blood Chloride Decreased	10	5.1	5.1	signal
366	Delirium	132	5.0	5.0	signal
367	Blood Lactic Acid Increased	20	5.0	5.0	signal
368	Stress Cardiomyopathy	22	5.0	5.0	signal
369	Post Transplant Lymphoproliferative Disorder	19	5.0	5.0	signal
370	Urine Output Decreased	33	4.9	5.0	signal
371	Bone Marrow Failure	77	4.9	5.0	signal
372	Lacunar Infarction	9	4.9	4.9	signal
373	Hypothermia	38	4.9	4.9	signal
374	Ventricular Hypokinesia	12	4.9	4.9	signal
375	Liver Injury	90	4.9	4.9	signal
376	Diabetes Insipidus	9	4.9	4.9	signal
377	Organ Failure	15	4.9	4.9	signal
378	Hepatic Necrosis	14	4.9	4.9	signal
379	Epstein-barr Virus Infection	23	4.9	4.9	signal
380	Rhinovirus Infection	14	4.8	4.8	signal
381	Inflammatory Marker Increased	18	4.8	4.8	signal
382	Serotonin Syndrome	70	4.8	4.8	signal
383	Catheter Site Haemorrhage	9	4.8	4.8	signal
384	Fibrin D Dimer Increased	13	4.8	4.8	signal
385	Transaminases Increased	81	4.8	4.8	signal
386	Drug Rash With Eosinophilia And Systemic Symptoms	12	4.8	4.8	signal
387	Subdural Haemorrhage	10	4.8	4.8	signal
388	Leukopenia	181	4.8	4.8	signal
389	Ventricular Tachycardia	60	4.8	4.8	signal
390	Lymphocyte Count Decreased	64	4.8	4.8	signal
391	Rales	21	4.7	4.8	signal
392	Hyperkalaemia	126	4.7	4.8	signal
393	Dermatitis Exfoliative	18	4.7	4.7	signal
394	Chest X-ray Abnormal	11	4.7	4.7	signal
395	Disseminated Tuberculosis	9	4.6	4.6	signal
396	Cachexia	18	4.6	4.6	signal
397	Hydrocephalus	19	4.6	4.6	signal
398	Altered State Of Consciousness	75	4.6	4.6	signal
399	Catheter Site Infection	13	4.6	4.6	signal
400	Prothrombin Time Prolonged	21	4.6	4.6	signal
401	Cardiac Failure Acute	23	4.5	4.5	signal
402	Hypomagnesaemia	48	4.5	4.6	signal
403	Aphasia	104	4.5	4.5	signal
404	Hyperreflexia	12	4.5	4.5	signal
405	Hypoxic-ischaemic Encephalopathy	9	4.5	4.5	signal
406	Hyperuricaemia	14	4.5	4.5	signal
407	Pneumothorax	54	4.5	4.5	signal
408	Hypophosphataemia	25	4.5	4.5	signal
409	Alanine Aminotransferase Increased	209	4.5	4.5	signal
410	Fluid Overload	50	4.4	4.5	signal
411	Hypokalaemia	153	4.4	4.4	signal
412	Pneumonitis	90	4.4	4.4	signal
413	Nephritis	11	4.4	4.4	signal
414	Cardiopulmonary Failure	13	4.4	4.4	signal
415	Faecaloma	18	4.3	4.3	signal
416	Chronic Graft Versus Host Disease	12	4.3	4.3	signal
417	Blood Albumin Decreased	26	4.3	4.3	signal
418	Purulent Discharge	14	4.3	4.3	signal
419	Failure To Thrive	17	4.3	4.3	signal
420	Bundle Branch Block Right	15	4.3	4.3	signal
421	Cerebral Atrophy	13	4.3	4.3	signal
422	Cytomegalovirus Infection	54	4.3	4.3	signal
423	Cardiogenic Shock	46	4.2	4.2	signal
424	Abdominal Tenderness	16	4.2	4.2	signal
425	Nephrogenic Anaemia	15	4.2	4.2	signal
426	Oesophagitis	35	4.2	4.2	signal
427	Bronchiectasis	21	4.1	4.1	signal
428	Pyrexia	1,086	4.1	4.3	signal
429	Pulmonary Toxicity	22	4.1	4.1	signal
430	Subarachnoid Haemorrhage	32	4.1	4.1	signal
431	Meningitis Aseptic	14	4.1	4.1	signal
432	Pyoderma Gangrenosum	11	4.0	4.0	signal
433	Hepatic Failure	93	4.0	4.1	signal
434	Renal Impairment	257	4.0	4.1	signal
435	Blood Alkaline Phosphatase Increased	76	4.0	4.0	signal
436	Hepatic Function Abnormal	113	4.0	4.0	signal
437	Electrolyte Imbalance	35	4.0	4.0	signal
438	Necrosis	17	4.0	4.0	signal
439	Intestinal Perforation	34	4.0	4.0	signal
440	Oral Candidiasis	39	3.9	3.9	signal
441	Transplant Rejection	24	3.9	3.9	signal
442	Right Ventricular Failure	21	3.9	3.9	signal
443	Hypotension	593	3.9	4.0	signal
444	Renal Failure Chronic	23	3.9	3.9	signal
445	Blood Lactate Dehydrogenase Increased	47	3.9	3.9	signal
446	Decubitus Ulcer	24	3.9	3.9	signal
447	Pneumonia Aspiration	73	3.8	3.9	signal
448	Supraventricular Tachycardia	28	3.8	3.8	signal
449	Renal Failure	386	3.8	3.9	signal
450	Diffuse Large B-cell Lymphoma	22	3.8	3.8	signal
451	Odynophagia	17	3.8	3.8	signal
452	C-reactive Protein Increased	104	3.8	3.8	signal
453	Cellulitis	144	3.7	3.8	signal
454	Tachycardia	253	3.7	3.8	signal
455	Hypercalcaemia	35	3.7	3.7	signal
456	Cardiac Arrest	234	3.7	3.7	signal
457	Escherichia Urinary Tract Infection	12	3.7	3.7	signal
458	Urosepsis	26	3.7	3.7	signal
459	Neurological Symptom	16	3.7	3.7	signal
460	Haematocrit Decreased	56	3.7	3.7	signal
461	Torsade De Pointes	22	3.7	3.7	signal
462	Malnutrition	31	3.7	3.7	signal
463	Ileus	34	3.6	3.6	signal
464	Platelet Count Decreased	294	3.6	3.7	signal
465	Ventricular Arrhythmia	10	3.6	3.6	signal
466	Oral Disorder	20	3.6	3.6	signal
467	Acute Hepatic Failure	37	3.6	3.6	signal
468	Depressed Level Of Consciousness	107	3.6	3.6	signal
469	Subcutaneous Abscess	13	3.6	3.6	signal
470	Ileus Paralytic	12	3.5	3.5	signal
471	Varicose Vein	14	3.5	3.5	signal
472	Cerebral Ischaemia	14	3.5	3.5	signal
473	Electrocardiogram Qt Prolonged	97	3.5	3.6	signal
474	International Normalised Ratio Increased	77	3.5	3.5	signal
475	Troponin Increased	20	3.5	3.5	signal
476	B-cell Lymphoma	9	3.5	3.5	signal
477	Myelodysplastic Syndrome	38	3.4	3.4	signal
478	Confusional State	425	3.4	3.5	signal
479	Conjunctival Haemorrhage	10	3.4	3.4	signal
480	Hypocalcaemia	49	3.4	3.4	signal
481	Bronchopneumonia	9	3.4	3.4	signal
482	Splenomegaly	30	3.4	3.4	signal
483	Hepatomegaly	25	3.3	3.3	signal
484	Retinal Haemorrhage	18	3.3	3.3	signal
485	Diverticulum Intestinal	11	3.3	3.3	signal
486	Rhabdomyolysis	105	3.3	3.3	signal
487	Cystic Fibrosis	14	3.3	3.3	signal
488	General Physical Condition Abnormal	17	3.3	3.3	signal
489	Cardiomyopathy	37	3.3	3.3	signal
490	Pneumonia	807	3.3	3.4	signal
491	Bone Lesion	9	3.3	3.3	signal
492	Fungal Infection	83	3.3	3.3	signal
493	Guillain-barre Syndrome	12	3.3	3.3	signal
494	Iron Deficiency	11	3.2	3.2	signal
495	Nephropathy	23	3.2	3.2	signal
496	Respiratory Syncytial Virus Infection	21	3.2	3.2	signal
497	Red Cell Distribution Width Increased	10	3.2	3.2	signal
498	Tenderness	25	3.1	3.1	signal
499	Brain Injury	24	3.1	3.1	signal
500	Metastases To Lymph Nodes	16	3.1	3.1	signal
501	Generalised Tonic-clonic Seizure	39	3.1	3.1	signal
502	Drug Level Below Therapeutic	13	3.1	3.1	signal
503	Ataxia	28	3.1	3.1	signal
504	Lymphopenia	33	3.1	3.1	signal
505	Adrenal Insufficiency	28	3.1	3.1	signal
506	Colitis	88	3.1	3.1	signal
507	Hepatitis Cholestatic	14	3.1	3.1	signal
508	Haemorrhage Intracranial	35	3.1	3.1	signal
509	Mouth Haemorrhage	17	3.0	3.0	signal
510	Cerebral Haemorrhage	82	3.0	3.0	signal
511	Lung Infection	36	3.0	3.0	signal
512	Pulmonary Function Test Decreased	10	3.0	3.0	signal
513	No Therapeutic Response	28	3.0	3.0	signal
514	Gamma-glutamyltransferase Increased	50	3.0	3.0	signal
515	Liver Function Test Increased	48	3.0	3.0	signal
516	Pulmonary Oedema	100	2.9	2.9	signal
517	Subdural Haematoma	32	2.9	2.9	signal
518	White Blood Cell Count Decreased	240	2.9	2.9	signal
519	Ascites	65	2.9	2.9	signal
520	Arthritis Bacterial	9	2.9	2.9	signal
521	Drug Interaction	347	2.9	2.9	signal
522	Ecchymosis	15	2.9	2.9	signal
523	Oxygen Saturation Decreased	121	2.8	2.9	signal
524	Cardio-respiratory Arrest	91	2.8	2.8	signal
525	Anaemia	411	2.8	2.9	signal
526	Spinal Osteoarthritis	19	2.8	2.8	signal
527	Tricuspid Valve Incompetence	17	2.8	2.8	signal
528	Erythema Multiforme	20	2.8	2.8	signal
529	Performance Status Decreased	10	2.8	2.8	signal
530	Acute Pulmonary Oedema	12	2.8	2.8	signal
531	Hyponatraemia	120	2.8	2.8	signal
532	Partial Seizures	11	2.8	2.8	signal
533	Cholecystitis Acute	12	2.8	2.8	signal
534	Peripheral Vascular Disorder	11	2.8	2.8	signal
535	Mitral Valve Incompetence	24	2.8	2.8	signal
536	Myocarditis	24	2.8	2.8	signal
537	Myositis	19	2.8	2.8	signal
538	Aortic Valve Incompetence	9	2.8	2.8	signal
539	Cholangitis	13	2.8	2.8	signal
540	Atrial Fibrillation	205	2.8	2.8	signal
541	Left Ventricular Hypertrophy	9	2.8	2.8	signal
542	Liver Disorder	93	2.8	2.8	signal
543	Cardiac Tamponade	10	2.8	2.8	signal
544	Melaena	46	2.7	2.7	signal
545	Postoperative Wound Infection	14	2.7	2.7	signal
546	Polyuria	17	2.7	2.7	signal
547	Abscess	33	2.7	2.7	signal
548	Hyperglycaemia	75	2.7	2.7	signal
549	Hepatic Encephalopathy	19	2.7	2.7	signal
550	Tuberculosis	26	2.6	2.7	signal
551	Cholecystitis	24	2.6	2.6	signal
552	Pulmonary Mass	30	2.6	2.6	signal
553	Proteinuria	38	2.6	2.6	signal
554	Hypophagia	51	2.6	2.6	signal
555	Hepatitis Acute	13	2.6	2.6	signal
556	Jaundice	54	2.6	2.6	signal
557	Petit Mal Epilepsy	10	2.6	2.6	signal
558	Skin Mass	13	2.6	2.6	signal
559	End Stage Renal Disease	36	2.6	2.6	signal
560	Central Nervous System Lesion	27	2.6	2.6	signal
561	Meningitis	13	2.5	2.6	signal
562	Ischaemia	9	2.5	2.6	signal
563	Appendicitis	18	2.5	2.5	signal
564	Pelvic Fracture	15	2.5	2.5	signal
565	Eosinophil Count Increased	16	2.5	2.5	signal
566	Interstitial Lung Disease	93	2.5	2.5	signal
567	Haematuria	66	2.5	2.5	signal
568	Petechiae	20	2.5	2.5	signal
569	Respiratory Rate Increased	17	2.5	2.5	signal
570	Bradycardia	100	2.5	2.5	signal
571	Multiple Injuries	12	2.5	2.5	signal
572	Emphysema	19	2.5	2.5	signal
573	White Blood Cell Count Increased	72	2.5	2.5	signal
574	Anal Abscess	10	2.4	2.4	signal
575	Sinus Bradycardia	18	2.4	2.4	signal
576	Myelosuppression	63	2.4	2.4	signal
577	Disorientation	73	2.4	2.4	signal
578	Refusal Of Treatment By Patient	12	2.4	2.4	signal
579	Myocardial Ischaemia	21	2.4	2.4	signal
580	Ventricular Extrasystoles	19	2.4	2.4	signal
581	Body Temperature Increased	37	2.4	2.4	signal
582	Ejection Fraction Decreased	28	2.4	2.4	signal
583	Ventricular Fibrillation	20	2.4	2.4	signal
584	Nervous System Disorder	56	2.3	2.3	signal
585	Apnoea	14	2.3	2.3	signal
586	Blood Calcium Decreased	20	2.3	2.3	signal
587	Face Oedema	30	2.3	2.3	signal
588	Coma	84	2.3	2.3	signal
589	Haemoptysis	49	2.3	2.3	signal
590	Nephrotic Syndrome	12	2.3	2.3	signal
591	Haemoglobin Decreased	180	2.3	2.3	signal
592	Peritonitis	36	2.3	2.3	signal
593	Pericardial Effusion	40	2.3	2.3	signal
594	Pulmonary Congestion	23	2.3	2.3	signal
595	Herpes Virus Infection	10	2.3	2.3	signal
596	Large Intestine Perforation	12	2.3	2.3	signal
597	Hypertriglyceridaemia	10	2.2	2.2	signal
598	Transfusion	18	2.2	2.2	signal
599	Cardiomegaly	21	2.2	2.2	signal
600	Dermatitis	35	2.2	2.2	signal
601	Endophthalmitis	10	2.2	2.2	signal
602	Spinal Compression Fracture	14	2.2	2.2	signal
603	Arteriosclerosis Coronary Artery	11	2.2	2.2	signal
604	Blood Potassium Increased	27	2.2	2.2	signal
605	Aspiration	18	2.2	2.2	signal
606	Respiratory Tract Infection	43	2.2	2.2	signal
607	Acute Myocardial Infarction	49	2.2	2.2	signal
608	Lethargy	95	2.2	2.2	signal
609	Facial Paralysis	14	2.2	2.2	signal
610	Renal Cyst	13	2.1	2.1	signal
611	Stomatitis	99	2.1	2.1	signal
612	Vasculitis	19	2.1	2.1	signal
613	Pyelonephritis	14	2.1	2.1	signal
614	Lower Gastrointestinal Haemorrhage	12	2.1	2.1	signal
615	Haematemesis	41	2.1	2.1	signal
616	Hydronephrosis	12	2.1	2.1	signal
617	Pulmonary Hypertension	33	2.1	2.1	signal
618	Enteritis	10	2.1	2.1	signal
619	Lipase Increased	12	2.1	2.1	signal
620	Hallucination, Visual	33	2.1	2.1	signal
621	Blood Creatine Phosphokinase Increased	46	2.1	2.1	signal
622	Drug Level Decreased	16	2.0	2.1	signal
623	Gastrointestinal Haemorrhage	131	2.0	2.0	signal
624	Neutrophil Count Increased	16	2.0	2.0	signal
625	Embolism	13	2.0	2.0	signal
626	Condition Aggravated	466	2.0	2.1	signal
627	Upper Gastrointestinal Haemorrhage	26	2.0	2.0	signal
628	Circulatory Collapse	26	2.0	2.0	no signal
629	Hyperlipidaemia	18	2.0	2.0	no signal
630	Myopathy	13	2.0	2.0	no signal
631	Oedema	81	2.0	2.0	no signal
632	Lymphadenopathy	53	2.0	2.0	no signal
633	Metastases To Central Nervous System	19	1.9	1.9	no signal
634	Mouth Ulceration	31	1.9	1.9	no signal
635	Inappropriate Antidiuretic Hormone Secretion	15	1.9	1.9	no signal
636	Wound Infection	16	1.9	1.9	no signal
637	Deep Vein Thrombosis	96	1.9	1.9	no signal
638	Skin Lesion	40	1.9	1.9	no signal
639	Red Blood Cell Count Decreased	42	1.9	1.9	no signal
640	Treatment Failure	120	1.9	1.9	no signal
641	Drug Toxicity	20	1.9	1.9	no signal
642	Epilepsy	44	1.9	1.9	no signal
643	Respiratory Arrest	40	1.9	1.9	no signal
644	Therapy Non-responder	64	1.9	1.9	no signal
645	Renal Disorder	67	1.9	1.9	no signal
646	Cardiac Failure	115	1.9	1.9	no signal
647	Anaphylactic Reaction	78	1.9	1.9	no signal
648	Hepatitis	36	1.8	1.8	no signal
649	Peritonitis Bacterial	14	1.8	1.8	no signal
650	Pancreatitis Acute	31	1.8	1.8	no signal
651	Off Label Use	1,204	1.8	1.9	no signal
652	Agitation	102	1.8	1.8	no signal
653	Rhinitis	11	1.8	1.8	no signal
654	Hepatotoxicity	30	1.8	1.8	no signal
655	Product Use In Unapproved Indication	330	1.8	1.8	no signal
656	Therapy Change	13	1.8	1.8	no signal
657	Haematoma	35	1.8	1.8	no signal
658	Neuroleptic Malignant Syndrome	16	1.8	1.8	no signal
659	Respiratory Disorder	40	1.7	1.7	no signal
660	Renal Injury	40	1.7	1.7	no signal
661	Fistula	15	1.7	1.7	no signal
662	Rash Erythematous	62	1.7	1.7	no signal
663	Glomerular Filtration Rate Decreased	16	1.7	1.7	no signal
664	Infection	190	1.7	1.7	no signal
665	Disease Progression	155	1.7	1.7	no signal
666	Skin Plaque	11	1.7	1.7	no signal
667	Muscle Twitching	30	1.7	1.7	no signal
668	Hallucination	97	1.7	1.7	no signal
669	Gastritis	34	1.7	1.7	no signal
670	Post Procedural Haemorrhage	15	1.7	1.7	no signal
671	Restlessness	47	1.7	1.7	no signal
672	Flank Pain	12	1.7	1.7	no signal
673	Product Prescribing Issue	26	1.7	1.7	no signal
674	Duodenal Ulcer	9	1.7	1.7	no signal
675	Toxicity To Various Agents	214	1.7	1.7	no signal
676	Sputum Discoloured	12	1.7	1.7	no signal
677	Immunosuppression	11	1.7	1.7	no signal
678	Dental Caries	14	1.7	1.7	no signal
679	Cardiac Murmur	11	1.7	1.7	no signal
680	Seizure	144	1.6	1.6	no signal
681	Lung Disorder	61	1.6	1.6	no signal
682	Chills	146	1.6	1.6	no signal
683	Rebound Effect	14	1.6	1.6	no signal
684	Haemarthrosis	11	1.6	1.6	no signal
685	Vitamin D Deficiency	12	1.6	1.6	no signal
686	Dysphagia	115	1.6	1.6	no signal
687	General Physical Health Deterioration	138	1.6	1.6	no signal
688	Drug Ineffective	1,563	1.6	1.6	no signal
689	Oral Herpes	23	1.5	1.5	no signal
690	Hepatic Steatosis	22	1.5	1.5	no signal
691	Blood Sodium Decreased	22	1.5	1.5	no signal
692	Liver Function Test Abnormal	34	1.5	1.5	no signal
693	Oral Pain	26	1.5	1.5	no signal
694	Hiatus Hernia	15	1.5	1.5	no signal
695	Cerebral Infarction	28	1.5	1.5	no signal
696	Pharyngitis	14	1.5	1.5	no signal
697	Bronchospasm	16	1.5	1.5	no signal
698	Rash Papular	25	1.5	1.5	no signal
699	Angioedema	49	1.5	1.5	no signal
700	Metastases To Bone	18	1.4	1.4	no signal
701	Pulmonary Fibrosis	21	1.4	1.4	no signal
702	Cardiac Failure Congestive	88	1.4	1.4	no signal
703	Skin Infection	12	1.4	1.4	no signal
704	Blood Pressure Decreased	71	1.4	1.4	no signal
705	Mass	15	1.4	1.4	no signal
706	Urinary Tract Infection	182	1.4	1.4	no signal
707	Grand Mal Convulsion	10	1.4	1.4	no signal
708	Arteriosclerosis	10	1.4	1.4	no signal
709	Leukaemia	10	1.4	1.4	no signal
710	Therapy Cessation	54	1.4	1.4	no signal
711	Rash Pruritic	57	1.4	1.4	no signal
712	Blister	59	1.4	1.4	no signal
713	Convulsion	61	1.4	1.4	no signal
714	Abdominal Pain	242	1.4	1.4	no signal
715	Disease Recurrence	49	1.3	1.3	no signal
716	Breast Cancer Metastatic	11	1.3	1.3	no signal
717	Anhedonia	27	1.3	1.3	no signal
718	Pulmonary Embolism	97	1.3	1.3	no signal
719	Infusion Related Reaction	67	1.3	1.3	no signal
720	Dyskinesia	41	1.3	1.3	no signal
721	Gastric Ulcer	19	1.3	1.3	no signal
722	Rash Generalised	26	1.3	1.3	no signal
723	Oedema Peripheral	120	1.3	1.3	no signal
724	Orthostatic Hypotension	17	1.3	1.3	no signal
725	Hypoglycaemia	47	1.3	1.3	no signal
726	Sedation	25	1.3	1.3	no signal
727	Neoplasm	11	1.3	1.3	no signal
728	Cyanosis	15	1.2	1.2	no signal
729	Immunodeficiency	14	1.2	1.2	no signal
730	Epistaxis	71	1.2	1.2	no signal
731	Hypercholesterolaemia	9	1.2	1.2	no signal
732	Dehydration	125	1.2	1.2	no signal
733	Mydriasis	12	1.2	1.2	no signal
734	Post Procedural Complication	18	1.2	1.2	no signal
735	Urinary Retention	31	1.2	1.2	no signal
736	Skin Ulcer	24	1.2	1.2	no signal
737	Rash	402	1.2	1.2	no signal
738	Rib Fracture	19	1.2	1.2	no signal
739	Polyneuropathy	11	1.2	1.2	no signal
740	Chronic Obstructive Pulmonary Disease	48	1.2	1.2	no signal
741	Nodule	12	1.2	1.2	no signal
742	Covid-19	162	1.2	1.2	no signal
743	Chronic Kidney Disease	70	1.2	1.2	no signal
744	Malignant Neoplasm Progression	93	1.2	1.2	no signal
745	Hepatic Enzyme Increased	62	1.2	1.2	no signal
746	Upper Respiratory Tract Infection	42	1.2	1.2	no signal
747	Productive Cough	43	1.2	1.2	no signal
748	Mental Impairment	22	1.2	1.2	no signal
749	Paralysis	13	1.2	1.2	no signal
750	Diabetes Mellitus Inadequate Control	16	1.2	1.2	no signal
751	Cognitive Disorder	42	1.2	1.2	no signal
752	Pericarditis	15	1.2	1.2	no signal
753	Plasma Cell Myeloma	35	1.2	1.2	no signal
754	Neoplasm Progression	31	1.2	1.2	no signal
755	Hemiparesis	15	1.2	1.2	no signal
756	Therapy Partial Responder	13	1.1	1.1	no signal
757	Intervertebral Disc Degeneration	8	1.1	1.1	no signal
758	Eyelid Oedema	10	1.1	1.1	no signal
759	Impaired Healing	28	1.1	1.1	no signal
760	Incontinence	9	1.1	1.1	no signal
761	Skin Fissures	16	1.1	1.1	no signal
762	Inflammation	43	1.1	1.1	no signal
763	Presyncope	20	1.1	1.1	no signal
764	Dysarthria	31	1.1	1.1	no signal
765	Parkinsonism	8	1.1	1.1	no signal
766	Anaphylactic Shock	21	1.1	1.1	no signal
767	Coronary Artery Disease	25	1.1	1.1	no signal
768	Scar	14	1.1	1.1	no signal
769	Red Blood Cell Sedimentation Rate Increased	9	1.1	1.1	no signal
770	Hypertension	171	1.1	1.1	no signal
771	Obstructive Airways Disorder	9	1.1	1.1	no signal
772	Hepatic Cirrhosis	15	1.1	1.1	no signal
773	Hypotonia	8	1.0	1.0	no signal
774	Cholelithiasis	26	1.0	1.0	no signal
775	Motor Dysfunction	8	1.0	1.0	no signal
776	Blood Triglycerides Increased	14	1.0	1.0	no signal
777	Osteopenia	12	1.0	1.0	no signal
778	Intentional Product Use Issue	69	1.0	1.0	no signal
779	Speech Disorder	41	1.0	1.0	no signal
780	Wheezing	46	1.0	1.0	no signal
781	Musculoskeletal Chest Pain	12	1.0	1.0	no signal
782	Incorrect Route Of Product Administration	13	1.0	1.0	no signal
783	Diarrhoea	496	1.0	1.0	no signal
784	Pallor	21	1.0	1.0	no signal
785	Haemorrhoids	15	1.0	1.0	no signal
786	Drug Hypersensitivity	149	1.0	1.0	no signal
787	Blood Pressure Systolic Increased	15	1.0	1.0	no signal
788	Platelet Count Increased	10	1.0	1.0	no signal
789	Osteonecrosis Of Jaw	19	1.0	1.0	no signal
790	Conjunctivitis	14	1.0	1.0	no signal
791	Premature Baby	23	1.0	1.0	no signal
792	Immune System Disorder	10	1.0	1.0	no signal
793	Decreased Appetite	176	1.0	1.0	no signal
794	Pulmonary Arterial Hypertension	11	1.0	1.0	no signal
795	Erythema	155	1.0	1.0	no signal
796	Drug Effective For Unapproved Indication	22	1.0	1.0	no signal
797	Chromaturia	17	1.0	1.0	no signal
798	Obesity	12	1.0	1.0	no signal
799	Premature Delivery	12	1.0	1.0	no signal
800	Photophobia	14	1.0	1.0	no signal
801	Diarrhoea Haemorrhagic	7	1.0	1.0	no signal
802	Cough	209	1.0	1.0	no signal
803	Deformity	7	1.0	1.0	no signal
804	Rash Macular	26	1.0	1.0	no signal
805	Pain In Jaw	21	1.0	1.0	no signal
806	Dysuria	27	1.0	1.0	no signal
807	Secretion Discharge	9	1.0	1.0	no signal
808	Palmar-plantar Erythrodysaesthesia Syndrome	17	1.0	1.0	no signal
809	Muscle Spasticity	9	0.9	0.9	no signal
810	Deafness	19	0.9	0.9	no signal
811	Gout	13	0.9	0.9	no signal
812	Dyspnoea Exertional	27	0.9	0.9	no signal
813	Pancreatitis	38	0.9	0.9	no signal
814	Extrapyramidal Disorder	18	0.9	0.9	no signal
815	Hypertensive Crisis	8	0.9	0.9	no signal
816	Abdominal Distension	74	0.9	0.9	no signal
817	Bone Disorder	13	0.9	0.9	no signal
818	Dyspnoea	399	0.9	0.9	no signal
819	Body Temperature Decreased	7	0.9	0.9	no signal
820	Bronchitis	52	0.9	0.9	no signal
821	Skin Exfoliation	58	0.9	0.9	no signal
822	Vomiting	327	0.9	0.9	no signal
823	Syncope	69	0.9	0.9	no signal
824	Haemorrhage	72	0.9	0.9	no signal
825	Eyelid Ptosis	7	0.9	0.9	no signal
826	Intervertebral Disc Protrusion	15	0.9	0.9	no signal
827	Constipation	148	0.9	0.9	no signal
828	Eczema	34	0.9	0.9	no signal
829	Insurance Issue	10	0.9	0.9	no signal
830	Maternal Exposure During Pregnancy	59	0.9	0.9	no signal
831	Muscular Weakness	76	0.9	0.9	no signal
832	Photosensitivity Reaction	11	0.9	0.9	no signal
833	Disturbance In Attention	36	0.9	0.9	no signal
834	Toothache	12	0.9	0.9	no signal
835	Herpes Zoster	38	0.9	0.9	no signal
836	Somnolence	132	0.9	0.9	no signal
837	Arrhythmia	31	0.9	0.9	no signal
838	Diverticulitis	18	0.9	0.9	no signal
839	Economic Problem	10	0.8	0.8	no signal
840	Asthenia	243	0.8	0.8	no signal
841	Tremor	106	0.8	0.8	no signal
842	Injury	45	0.8	0.8	no signal
843	Squamous Cell Carcinoma	6	0.8	0.8	no signal
844	Thrombosis	51	0.8	0.8	no signal
845	Blood Potassium Decreased	19	0.8	0.8	no signal
846	Accidental Overdose	23	0.8	0.8	no signal
847	Hypothyroidism	20	0.8	0.8	no signal
848	Metastases To Liver	11	0.8	0.8	no signal
849	Diabetic Ketoacidosis	15	0.8	0.8	no signal
850	Treatment Noncompliance	34	0.8	0.8	no signal
851	Local Swelling	11	0.8	0.8	no signal
852	Prescribed Overdose	12	0.8	0.8	no signal
853	Dystonia	12	0.8	0.8	no signal
854	Urticaria	102	0.8	0.8	no signal
855	Exposure During Pregnancy	38	0.8	0.8	no signal
856	Overdose	132	0.8	0.8	no signal
857	Hospice Care	6	0.8	0.8	no signal
858	Sars-cov-2 Test Positive	8	0.8	0.8	no signal
859	Mental Disorder	26	0.8	0.8	no signal
860	Intestinal Obstruction	22	0.8	0.8	no signal
861	Muscle Rigidity	7	0.8	0.8	no signal
862	Fracture	11	0.8	0.8	no signal
863	Folliculitis	6	0.8	0.8	no signal
864	Respiratory Depression	7	0.7	0.7	no signal
865	Chest Pain	105	0.7	0.7	no signal
866	Neuropathy Peripheral	53	0.7	0.7	no signal
867	Skin Haemorrhage	8	0.7	0.7	no signal
868	Fear	15	0.7	0.7	no signal
869	Taste Disorder	11	0.7	0.7	no signal
870	Nephrolithiasis	25	0.7	0.7	no signal
871	Increased Tendency To Bruise	5	0.7	0.7	no signal
872	Back Pain	126	0.7	0.7	no signal
873	Wound	15	0.7	0.7	no signal
874	Haematotoxicity	5	0.7	0.7	no signal
875	Swelling	50	0.7	0.7	no signal
876	Hypersensitivity	99	0.7	0.7	no signal
877	Cystitis	17	0.7	0.7	no signal
878	Abortion Induced	5	0.7	0.7	no signal
879	Complication Associated With Device	7	0.7	0.7	no signal
880	Micturition Urgency	6	0.7	0.7	no signal
881	Cholecystectomy	6	0.7	0.7	no signal
882	Adverse Reaction	7	0.7	0.7	no signal
883	Nausea	416	0.7	0.7	no signal
884	Laceration	5	0.7	0.7	no signal
885	Blood Count Abnormal	8	0.7	0.7	no signal
886	Metastases To Lung	6	0.7	0.7	no signal
887	Paranoia	9	0.7	0.7	no signal
888	Gingival Bleeding	7	0.7	0.7	no signal
889	Therapeutic Product Effect Incomplete	36	0.7	0.7	no signal
890	Urinary Incontinence	15	0.7	0.7	no signal
891	Oropharyngeal Pain	46	0.7	0.6	no signal
892	Nocturia	6	0.6	0.6	no signal
893	Hepatitis C	6	0.6	0.6	no signal
894	Paraesthesia Oral	7	0.6	0.6	no signal
895	Skin Disorder	16	0.6	0.6	no signal
896	Haematochezia	26	0.6	0.6	no signal
897	Impaired Gastric Emptying	6	0.6	0.6	no signal
898	Retching	10	0.6	0.6	no signal
899	Diabetes Mellitus	36	0.6	0.6	no signal
900	Sinusitis	48	0.6	0.6	no signal
901	Decreased Activity	5	0.6	0.6	no signal
902	Influenza	52	0.6	0.6	no signal
903	Therapeutic Response Decreased	28	0.6	0.6	no signal
904	Gastrointestinal Disorder	41	0.6	0.6	no signal
905	Osteoporosis	19	0.6	0.6	no signal
906	Loss Of Consciousness	59	0.6	0.6	no signal
907	Anorexia	6	0.6	0.6	no signal
908	Localised Infection	11	0.6	0.6	no signal
909	Lymphoma	7	0.6	0.6	no signal
910	Pruritus	170	0.6	0.6	no signal
911	Nerve Injury	5	0.6	0.6	no signal
912	Basal Cell Carcinoma	7	0.6	0.6	no signal
913	Osteoarthritis	19	0.6	0.6	no signal
914	Full Blood Count Decreased	9	0.6	0.6	no signal
915	Swelling Face	29	0.6	0.6	no signal
916	Type 2 Diabetes Mellitus	15	0.6	0.6	no signal
917	Respiratory Tract Congestion	7	0.6	0.6	no signal
918	No Adverse Event	78	0.6	0.6	no signal
919	Product Use Issue	82	0.6	0.6	no signal
920	Therapy Interrupted	30	0.6	0.6	no signal
921	Heart Rate Increased	43	0.6	0.6	no signal
922	Coordination Abnormal	6	0.6	0.6	no signal
923	Heart Rate Decreased	15	0.6	0.6	no signal
924	Systemic Lupus Erythematosus	15	0.6	0.6	no signal
925	Myalgia	72	0.6	0.6	no signal
926	Osteonecrosis	14	0.6	0.6	no signal
927	Spinal Disorder	4	0.6	0.6	no signal
928	Lip Swelling	14	0.6	0.6	no signal
929	Fall	139	0.5	0.5	no signal
930	Rectal Haemorrhage	18	0.5	0.5	no signal
931	Blood Glucose Decreased	20	0.5	0.5	no signal
932	Hyperthyroidism	6	0.5	0.5	no signal
933	Dysphonia	24	0.5	0.5	no signal
934	Bone Pain	24	0.5	0.5	no signal
935	Foetal Exposure During Pregnancy	33	0.5	0.5	no signal
936	Tendon Rupture	5	0.5	0.5	no signal
937	Night Sweats	13	0.5	0.5	no signal
938	Hyperhidrosis	52	0.5	0.5	no signal
939	Cyst	5	0.5	0.5	no signal
940	Dermatitis Allergic	5	0.5	0.5	no signal
941	Death	345	0.5	0.5	no signal
942	Salivary Hypersecretion	4	0.5	0.5	no signal
943	Gastrooesophageal Reflux Disease	32	0.5	0.5	no signal
944	Abdominal Pain Lower	10	0.5	0.5	no signal
945	Ischaemic Stroke	7	0.5	0.5	no signal
946	Viral Infection	13	0.5	0.5	no signal
947	Gallbladder Disorder	7	0.5	0.5	no signal
948	Ear Discomfort	4	0.5	0.5	no signal
949	Cerebrovascular Accident	65	0.5	0.5	no signal
950	Irritability	23	0.5	0.5	no signal
951	Full Blood Count Abnormal	4	0.5	0.5	no signal
952	Aggression	19	0.5	0.5	no signal
953	Anxiety	108	0.5	0.5	no signal
954	Medication Error	21	0.5	0.5	no signal
955	Nasal Congestion	22	0.5	0.5	no signal
956	Neck Pain	21	0.5	0.5	no signal
957	Sudden Death	4	0.5	0.5	no signal
958	Frequent Bowel Movements	10	0.5	0.5	no signal
959	Neuralgia	9	0.5	0.5	no signal
960	Pharyngitis Streptococcal	4	0.5	0.5	no signal
961	Pain In Extremity	108	0.5	0.5	no signal
962	Mania	6	0.5	0.5	no signal
963	Gait Inability	12	0.5	0.5	no signal
964	Procedural Pain	10	0.5	0.5	no signal
965	Musculoskeletal Pain	19	0.5	0.5	no signal
966	Drug Prescribing Error	7	0.5	0.5	no signal
967	Skin Reaction	5	0.5	0.5	no signal
968	Contusion	34	0.5	0.5	no signal
969	Amnesia	23	0.5	0.5	no signal
970	Heart Rate Irregular	8	0.5	0.5	no signal
971	Weight Decreased	98	0.5	0.5	no signal
972	Abnormal Behaviour	14	0.5	0.5	no signal
973	Internal Haemorrhage	4	0.5	0.5	no signal
974	Skin Discolouration	16	0.5	0.5	no signal
975	Hospitalisation	53	0.5	0.5	no signal
976	Angina Pectoris	10	0.5	0.5	no signal
977	Incorrect Product Administration Duration	7	0.5	0.5	no signal
978	Chest Discomfort	35	0.4	0.4	no signal
979	Drug Intolerance	33	0.4	0.4	no signal
980	Palpitations	40	0.4	0.4	no signal
981	Psychotic Disorder	10	0.4	0.4	no signal
982	Drug Withdrawal Syndrome	30	0.4	0.4	no signal
983	Fluid Retention	17	0.4	0.4	no signal
984	Drug Withdrawal Syndrome Neonatal	5	0.4	0.4	no signal
985	Unevaluable Event	25	0.4	0.4	no signal
986	Brain Neoplasm	3	0.4	0.4	no signal
987	Delusion	5	0.4	0.4	no signal
988	Tendonitis	5	0.4	0.4	no signal
989	Tooth Extraction	4	0.4	0.4	no signal
990	Personality Change	3	0.4	0.4	no signal
991	Pruritus Generalised	7	0.4	0.4	no signal
992	Hypersomnia	9	0.4	0.4	no signal
993	Fatigue	243	0.4	0.4	no signal
994	Intraocular Pressure Increased	4	0.4	0.4	no signal
995	Erectile Dysfunction	8	0.4	0.4	no signal
996	Rhinorrhoea	20	0.4	0.4	no signal
997	Pain	190	0.4	0.4	no signal
998	Blood Glucose Increased	57	0.4	0.4	no signal
999	Prescribed Underdose	6	0.4	0.4	no signal
1000	Weight Increased	67	0.4	0.4	no signal
1001	Headache	188	0.4	0.4	no signal
1002	Sopor	4	0.4	0.4	no signal
1003	Ovarian Cyst	3	0.4	0.4	no signal
1004	Pregnancy	6	0.4	0.4	no signal
1005	Akathisia	4	0.4	0.4	no signal
1006	Emotional Distress	35	0.4	0.4	no signal
1007	Device Occlusion	4	0.4	0.4	no signal
1008	Tooth Loss	6	0.4	0.4	no signal
1009	Abdominal Pain Upper	59	0.4	0.4	no signal
1010	Blindness Unilateral	4	0.4	0.4	no signal
1011	Surgery	16	0.4	0.4	no signal
1012	Product Dispensing Error	6	0.4	0.4	no signal
1013	Blood Glucose Fluctuation	3	0.4	0.4	no signal
1014	Burning Sensation	19	0.4	0.4	no signal
1015	Visual Impairment	33	0.4	0.3	no signal
1016	Product Availability Issue	6	0.4	0.3	no signal
1017	Cardiac Disorder	25	0.3	0.3	no signal
1018	Blood Pressure Increased	40	0.3	0.3	no signal
1019	Drug Administration Error	8	0.3	0.3	no signal
1020	Malaise	112	0.3	0.3	no signal
1021	Dysgeusia	19	0.3	0.3	no signal
1022	Depression	58	0.3	0.3	no signal
1023	Loss Of Personal Independence In Daily Activities	12	0.3	0.3	no signal
1024	Activities Of Daily Living Impaired	5	0.3	0.3	no signal
1025	Discomfort	15	0.3	0.3	no signal
1026	Tardive Dyskinesia	7	0.3	0.3	no signal
1027	Libido Decreased	3	0.3	0.3	no signal
1028	Asthma	27	0.3	0.3	no signal
1029	Ocular Hyperaemia	11	0.3	0.3	no signal
1030	Dizziness	117	0.3	0.3	no signal
1031	Balance Disorder	20	0.3	0.3	no signal
1032	Ankylosing Spondylitis	3	0.3	0.3	no signal
1033	Vision Blurred	31	0.3	0.3	no signal
1034	Hypoaesthesia	34	0.3	0.3	no signal
1035	Mobility Decreased	16	0.3	0.3	no signal
1036	Dry Mouth	18	0.3	0.3	no signal
1037	Therapeutic Response Unexpected	10	0.3	0.3	no signal
1038	Myocardial Infarction	39	0.3	0.3	no signal
1039	Peripheral Swelling	34	0.3	0.3	no signal
1040	Lower Respiratory Tract Infection	10	0.3	0.3	no signal
1041	Adverse Event	20	0.3	0.3	no signal
1042	Abdominal Discomfort	36	0.3	0.3	no signal
1043	Arthropathy	12	0.3	0.3	no signal
1044	Paraesthesia	33	0.3	0.3	no signal
1045	Arthralgia	86	0.3	0.3	no signal
1046	Adverse Drug Reaction	18	0.3	0.3	no signal
1047	Intentional Self-injury	4	0.3	0.3	no signal
1048	Bone Loss	3	0.3	0.3	no signal
1049	Ill-defined Disorder	12	0.3	0.3	no signal
1050	Vertigo	12	0.3	0.3	no signal
1051	Flushing	20	0.3	0.3	no signal
1052	Injection Site Warmth	4	0.3	0.3	no signal
1053	Gait Disturbance	37	0.3	0.3	no signal
1054	Insomnia	51	0.3	0.2	no signal
1055	Muscle Spasms	35	0.2	0.2	no signal
1056	Depressed Mood	10	0.2	0.2	no signal
1057	Withdrawal Syndrome	8	0.2	0.2	no signal
1058	Dry Eye	9	0.2	0.2	no signal
1059	Suicidal Ideation	17	0.2	0.2	no signal
1060	Memory Impairment	25	0.2	0.2	no signal
1061	Influenza Like Illness	15	0.2	0.2	no signal
1062	Multiple Fractures	3	0.2	0.2	no signal
1063	Illness	18	0.2	0.2	no signal
1064	Arthritis	14	0.2	0.2	no signal
1065	Nervousness	9	0.2	0.2	no signal
1066	Synovitis	3	0.2	0.2	no signal
1067	Underdose	12	0.2	0.2	no signal
1068	Inappropriate Schedule Of Product Administration	29	0.2	0.2	no signal
1069	Eye Pain	9	0.2	0.2	no signal
1070	Feeling Hot	10	0.2	0.2	no signal
1071	Drug Effect Incomplete	6	0.2	0.2	no signal
1072	Intentional Product Misuse	14	0.2	0.2	no signal
1073	Injection Site Reaction	11	0.2	0.2	no signal
1074	Musculoskeletal Stiffness	14	0.2	0.2	no signal
1075	Gastric Cancer	4	0.2	0.2	no signal
1076	Dyspepsia	15	0.2	0.2	no signal
1077	Product Dose Omission	10	0.2	0.2	no signal
1078	Neoplasm Malignant	10	0.2	0.2	no signal
1079	Incorrect Dose Administered	33	0.2	0.2	no signal
1080	Drug Exposure During Pregnancy	5	0.2	0.2	no signal
1081	Sleep Disorder	10	0.2	0.2	no signal
1082	Incorrect Drug Administration Duration	4	0.2	0.2	no signal
1083	Inappropriate Schedule Of Drug Administration	10	0.2	0.2	no signal
1084	Alopecia	26	0.2	0.2	no signal
1085	Joint Swelling	15	0.2	0.2	no signal
1086	Nasopharyngitis	23	0.2	0.2	no signal
1087	Product Dose Omission Issue	35	0.2	0.2	no signal
1088	Dry Skin	15	0.1	0.1	no signal
1089	Pharmaceutical Product Complaint	3	0.1	0.1	no signal
1090	Device Malfunction	7	0.1	0.1	no signal
1091	Device Leakage	4	0.1	0.1	no signal
1092	Renal Cancer	4	0.1	0.1	no signal
1093	Feeling Abnormal	19	0.1	0.1	no signal
1094	Psoriasis	10	0.1	0.1	no signal
1095	Device Breakage	3	0.1	0.1	no signal
1096	Prostate Cancer	5	0.1	0.1	no signal
1097	Injection Site Pain	13	0.1	0.1	no signal