OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Methaemoglobinaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,271 reports · 89 co-occurring drugs

As of the last recalculation, Methaemoglobinaemia appears in 2,271 FAERS reports alongside 89 co-occurring drug terms. The strongest observed disproportionality signal is DASPONE (PRR 566.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Daspone476566.4595.7
Dapsone Gel, 5%476566.3595.5
Dapsone480522.3547.0
Lidocaine Hydrochloride29852.052.3
Lidocaine Hydrochloride And Epinephrine24551.251.5
Lidicaine24451.151.3
Burn Relief24451.151.3
Lidocaine, Menthol24450.450.6
Lidocaine Hydrochloride And Epinephrine Bitartrate25148.348.6
Lidocaine 4%24846.746.9
Lidocaine24843.643.8
Norepinephrine4842.042.2
Cefepime6039.439.5
Cefepime Hydrochloride6035.035.2
Norepinephrine Bitartrate5032.532.6
Atovaquone2225.325.3
Rifampin3824.224.3
Gentamicin3021.321.3
Meropenem6619.419.4
Gentamicin Sulfate3017.617.7
Clindamycin4815.815.8
Midazolam4215.515.6
Posaconazole Delayed-Release1815.115.2
Midazolam Hydrochloride4314.914.9
Clindamycin Phosphate5114.314.3
Propofol5413.913.9
Nicotine Polacrilex Mini2213.613.6
Nicotine Polarilex2213.613.6
Dextrose1913.313.3
Dextrose Monohydrate1913.113.1
Magnesium Sulfate In Water For1813.013.0
Magnesium Sulfate Heptahydrate1812.812.8
Magnesium Sulfate1812.712.8
Sodium Bicarbonate3012.012.0
Sodium Bicarbonate Injection,3012.012.0
Oseltamivir1011.611.6
Iohexol1011.111.1
Doxycycline Hyclate7510.510.5
Piperacillin Sodium,Tazobactam Sodium3010.510.5
Doxycycline7410.210.3
Posaconazole1810.210.2
Ampicillin910.010.0
Ampicillin Sodium910.010.0
Sennosides 8.6 Mg Tablets219.39.3
Senna219.29.2
Calcium Gluconate129.29.2
Bupivacaine98.98.9
Acetaminophen Tablet Extended Release2208.68.7
Pain Reliever2208.68.6
Acetaminophen 500Mg2208.68.6
Senna Leaf218.48.4
Methoxy Polyethylene Glycol-Epoetin Beta108.38.3
Remdesivir128.38.3
Azithromycin Monohydrate378.38.3
Methocarbamol Tablets158.38.3
Azithromycin358.18.1
Hydroxychloroquine648.18.1
Hydroxyzine418.08.0
Fentanyl827.97.9
Iron Sucrose87.77.7
Polyethylene Glycol97.67.7
Vancomycin477.67.6
Valganciclovir Hydrochloride Powder,107.57.5
Vancomycin Hydrochloride537.57.5
Mercaptopurine147.47.4
Valganciclovir157.37.3
Valganciclovir Hydrochloride157.37.3
Sennosides237.17.1
Phenobarbital117.07.0
Amphetamine66.76.7
Metoclopramide396.66.6
Escitslopram416.66.6
Rocuronium Bromide86.26.2
Isosorbide Dinitrate136.16.1
Bumetanide175.95.9
Doxazosin185.95.9
Insulin Glargine-Yfgn145.95.9
Sevoflurane55.55.5
Bupropion265.45.4
Nicotine Polacrilex225.35.3
Nicotine235.35.3
Cytarabine324.94.9
Alteplase84.94.9
Carfilzomib144.64.6
Temozolomide93.93.9
Oseltamivir Phosphate103.83.8
Ethyl Alcohol93.03.0
Minoxidil Foam 5% (Womens)82.22.2
Minoxidil81.61.6

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.