OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Drospirenone And Ethinyl Estradiol

1,133 flagged reaction(s) · 178,006 total co-reports · max PRR 2,819.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Withdrawal Bleeding Irregular 210 2,819.8 2,833.3 signal
2 Gallbladder Injury 1,616 2,540.0 2,636.9 signal
3 Biliary Dyskinesia 1,428 2,532.5 2,617.5 signal
4 Cholecystitis Chronic 5,533 2,233.9 2,555.6 signal
5 Gallbladder Cholesterolosis 359 1,757.5 1,771.9 signal
6 Cholesterosis 189 1,287.3 1,292.8 signal
7 Post Cholecystectomy Syndrome 193 1,067.1 1,071.8 signal
8 Gallbladder Non-functioning 354 777.4 783.7 signal
9 Murphy's Sign Positive 18 445.2 445.4 signal
10 Abnormal Withdrawal Bleeding 314 253.1 254.9 signal
11 Fat Intolerance 32 242.6 242.7 signal
12 Pelvic Venous Thrombosis 458 223.0 225.4 signal
13 Hepatobiliary Scan Abnormal 40 216.1 216.3 signal
14 Fear Of Disease 547 209.5 212.1 signal
15 Thrombophlebitis Superficial 919 203.6 208.0 signal
16 Transverse Sinus Thrombosis 153 193.8 194.5 signal
17 Intracranial Venous Sinus Thrombosis 294 177.8 179.0 signal
18 Gallbladder Disorder 4,051 139.8 153.9 signal
19 Withdrawal Bleed 163 137.8 138.3 signal
20 Gallbladder Pain 146 134.0 134.5 signal
21 Pulmonary Infarction 505 128.4 129.8 signal
22 Embolism Arterial 243 121.0 121.6 signal
23 Medical Diet 39 117.5 117.6 signal
24 Superior Sagittal Sinus Thrombosis 157 115.1 115.5 signal
25 Cholecystitis Acute 1,095 114.7 117.6 signal
26 Pregnancy On Oral Contraceptive 501 111.9 113.1 signal
27 Biliary Colic 535 109.3 110.6 signal
28 Ovarian Vein Thrombosis 27 104.0 104.1 signal
29 Axillary Vein Thrombosis 63 98.4 98.5 signal
30 Post Thrombotic Syndrome 76 96.3 96.4 signal
31 Iliac Vein Occlusion 10 92.1 92.2 signal
32 Cholecystectomy 1,785 89.0 92.7 signal
33 Contact Lens Intolerance 24 85.4 85.5 signal
34 Injury 10,712 85.3 112.5 signal
35 Post Gastric Surgery Syndrome 12 72.3 72.3 signal
36 Paradoxical Embolism 14 71.5 71.5 signal
37 Deep Vein Thrombosis 8,259 69.1 84.8 signal
38 Cholecystitis 1,489 68.3 70.7 signal
39 Cholelithiasis 4,101 68.2 75.1 signal
40 Fear Of Death 248 59.5 59.8 signal
41 Vena Cava Thrombosis 175 55.9 56.2 signal
42 Subclavian Vein Thrombosis 117 54.4 54.5 signal
43 Pulmonary Embolism 9,171 50.7 63.8 signal
44 Phlebitis Superficial 39 47.7 47.8 signal
45 Bile Duct Stone 269 44.4 44.7 signal
46 Anhedonia 2,241 44.1 46.4 signal
47 Jugular Vein Thrombosis 148 43.6 43.8 signal
48 Mesenteric Vein Thrombosis 80 41.4 41.5 signal
49 Metrorrhagia 1,354 40.5 41.7 signal
50 Serum Amyloid A Protein Increased 12 39.7 39.7 signal
51 Premenstrual Syndrome 101 38.1 38.2 signal
52 Hepatic Adenoma 37 36.7 36.7 signal
53 Chloasma 33 36.6 36.6 signal
54 Splenic Vein Thrombosis 35 35.8 35.9 signal
55 Hydrocholecystis 13 35.7 35.7 signal
56 Internal Injury 45 35.0 35.0 signal
57 Psychological Trauma 589 34.4 34.9 signal
58 Cavernous Sinus Thrombosis 17 34.3 34.3 signal
59 Venous Insufficiency 49 34.2 34.3 signal
60 Focal Nodular Hyperplasia 35 33.9 33.9 signal
61 Hypomenorrhoea 168 32.8 32.9 signal
62 Benign Hepatic Neoplasm 13 32.7 32.7 signal
63 Blood Aldosterone Increased 11 32.3 32.3 signal
64 Blood Copper Increased 11 32.3 32.3 signal
65 Cerebral Venous Thrombosis 111 30.9 31.0 signal
66 Cerebral Artery Thrombosis 30 29.4 29.4 signal
67 May-thurner Syndrome 10 28.7 28.7 signal
68 Gallbladder Polyp 43 27.8 27.8 signal
69 Pleuritic Pain 152 27.6 27.7 signal
70 Intracardiac Thrombus 170 27.5 27.6 signal
71 Cor Pulmonale Acute 15 27.0 27.0 signal
72 Emotional Distress 6,361 26.3 30.6 signal
73 Polymenorrhoea 167 26.0 26.1 signal
74 Renal Vein Thrombosis 33 24.9 24.9 signal
75 High Risk Pregnancy 20 24.7 24.7 signal
76 Antepartum Haemorrhage 20 23.7 23.7 signal
77 Cerebral Thrombosis 125 22.0 22.1 signal
78 Sphincter Of Oddi Dysfunction 18 21.8 21.8 signal
79 Venous Injury 40 21.3 21.3 signal
80 Menstruation Delayed 428 20.5 20.7 signal
81 Organ Failure 161 19.7 19.8 signal
82 Portal Vein Thrombosis 126 19.4 19.5 signal
83 Thalamic Infarction 23 19.2 19.2 signal
84 Fear 1,039 19.0 19.4 signal
85 Hepatic Vein Thrombosis 12 18.7 18.7 signal
86 Menometrorrhagia 69 18.6 18.6 signal
87 Arterial Thrombosis Limb 15 17.6 17.6 signal
88 Fibroadenoma Of Breast 16 17.4 17.5 signal
89 Post Procedural Bile Leak 11 17.3 17.3 signal
90 Peripheral Artery Thrombosis 48 16.8 16.8 signal
91 Thrombophlebitis 118 16.5 16.5 signal
92 Pancreatic Injury 10 16.3 16.3 signal
93 Pulmonary Artery Thrombosis 25 15.9 16.0 signal
94 Spider Vein 19 14.6 14.6 signal
95 Thrombotic Stroke 22 14.5 14.5 signal
96 Amenorrhoea 493 14.5 14.7 signal
97 Basal Ganglia Infarction 10 14.1 14.1 signal
98 General Physical Health Deterioration 3,267 13.9 15.0 signal
99 Bile Duct Obstruction 54 13.8 13.8 signal
100 Painful Respiration 66 13.4 13.4 signal
101 Cerebral Artery Occlusion 29 13.3 13.3 signal
102 Lower Extremity Mass 17 13.3 13.3 signal
103 Post Procedural Diarrhoea 13 12.5 12.5 signal
104 Cholecystitis Infective 70 12.3 12.4 signal
105 Thrombosis 2,034 12.3 12.9 signal
106 Haemorrhage In Pregnancy 36 12.2 12.2 signal
107 Embolism Venous 76 12.2 12.3 signal
108 Polycystic Ovaries 39 12.1 12.1 signal
109 Haemangioma Of Liver 25 12.1 12.1 signal
110 Menorrhagia 482 11.8 11.9 signal
111 Anxiety 6,895 11.8 13.8 signal
112 Drug Withdrawal Headache 10 11.7 11.7 signal
113 Mental Disorder 1,036 11.6 11.9 signal
114 Gallbladder Enlargement 25 11.5 11.5 signal
115 Breast Enlargement 77 11.4 11.5 signal
116 Scar 400 11.4 11.5 signal
117 Breast Discomfort 24 11.3 11.4 signal
118 Oligomenorrhoea 50 11.2 11.2 signal
119 Viith Nerve Paralysis 80 11.1 11.2 signal
120 Cerebellar Infarction 38 11.0 11.0 signal
121 Venous Thrombosis Limb 47 10.9 10.9 signal
122 Deformity 205 10.7 10.7 signal
123 Traumatic Lung Injury 42 10.5 10.5 signal
124 Breast Tenderness 163 10.5 10.5 signal
125 Hemianaesthesia 17 10.2 10.2 signal
126 Pain 12,869 10.2 14.0 signal
127 Quality Of Life Decreased 270 9.8 9.8 signal
128 Agraphia 12 9.7 9.7 signal
129 Ischaemic Cerebral Infarction 23 9.6 9.6 signal
130 Embolic Stroke 69 9.6 9.6 signal
131 Retinal Vascular Thrombosis 10 9.3 9.3 signal
132 Coital Bleeding 29 9.3 9.3 signal
133 Breast Swelling 51 9.1 9.2 signal
134 Hypercoagulation 36 9.1 9.1 signal
135 Benign Intracranial Hypertension 23 8.8 8.8 signal
136 Adnexa Uteri Pain 23 8.7 8.7 signal
137 Hemianopia Homonymous 13 8.6 8.6 signal
138 Varicose Vein 92 8.6 8.6 signal
139 Life Expectancy Shortened 10 8.5 8.5 signal
140 Haemorrhagic Cerebral Infarction 12 8.2 8.2 signal
141 Abdominal Tenderness 84 8.2 8.2 signal
142 Biliary Tract Disorder 23 8.1 8.1 signal
143 Procedural Nausea 13 8.0 8.0 signal
144 Migraine With Aura 44 7.9 7.9 signal
145 Splenic Infarction 28 7.8 7.8 signal
146 Scotoma 12 7.7 7.7 signal
147 Infertility Female 24 7.6 7.6 signal
148 Ovarian Cyst Ruptured 20 7.5 7.6 signal
149 Brain Stem Infarction 16 7.5 7.6 signal
150 Retinal Vein Thrombosis 11 7.5 7.5 signal
151 Genital Haemorrhage 201 7.5 7.5 signal
152 Procedural Vomiting 10 7.5 7.5 signal
153 Incision Site Pain 18 7.4 7.4 signal
154 Hemianopia 15 7.3 7.3 signal
155 Pulmonary Thrombosis 162 7.2 7.2 signal
156 Vaginal Haemorrhage 628 7.1 7.2 signal
157 Menstrual Disorder 120 7.1 7.1 signal
158 Biliary Dilatation 21 6.9 6.9 signal
159 Venous Thrombosis 56 6.9 6.9 signal
160 Pleurisy 82 6.6 6.6 signal
161 Peripheral Embolism 16 6.6 6.6 signal
162 Breast Discharge 24 6.6 6.6 signal
163 Abortion Missed 17 6.4 6.4 signal
164 Hypoaesthesia Facial 20 6.3 6.3 signal
165 Vulvovaginal Dryness 42 6.3 6.3 signal
166 Ovarian Cyst 130 6.2 6.3 signal
167 Non-cardiac Chest Pain 41 6.2 6.2 signal
168 Food Intolerance 47 6.2 6.2 signal
169 Endometriosis 61 6.2 6.2 signal
170 Retinal Vein Occlusion 36 6.1 6.1 signal
171 Hemiparesis 210 5.9 6.0 signal
172 Vulvovaginal Mycotic Infection 48 5.9 5.9 signal
173 Cerebral Venous Sinus Thrombosis 10 5.9 5.9 signal
174 Abdominal Pain 2,772 5.7 6.1 signal
175 Coronary Artery Dissection 10 5.7 5.7 signal
176 Uterine Pain 12 5.7 5.7 signal
177 Carotid Artery Thrombosis 10 5.6 5.6 signal
178 Ectopic Pregnancy 36 5.6 5.6 signal
179 Hepatic Neoplasm 38 5.6 5.6 signal
180 Depression Suicidal 40 5.6 5.6 signal
181 Abdominal Pain Lower 293 5.6 5.6 signal
182 Pregnancy On Contraceptive 17 5.6 5.6 signal
183 Heart Injury 29 5.5 5.5 signal
184 Postural Orthostatic Tachycardia Syndrome 15 5.5 5.5 signal
185 Cerebral Artery Embolism 14 5.5 5.5 signal
186 Fibrin D Dimer Increased 40 5.4 5.4 signal
187 Cystitis Interstitial 18 5.4 5.4 signal
188 Retinal Artery Occlusion 28 5.3 5.3 signal
189 Breast Pain 118 5.3 5.3 signal
190 Renal Infarct 16 5.3 5.3 signal
191 Dysmenorrhoea 143 5.3 5.3 signal
192 Hemiplegia 91 5.2 5.3 signal
193 Arterial Thrombosis 21 5.2 5.2 signal
194 Pelvic Inflammatory Disease 16 5.1 5.1 signal
195 Post-traumatic Stress Disorder 71 5.1 5.1 signal
196 Dysfunctional Uterine Bleeding 13 5.1 5.1 signal
197 Vulvovaginal Candidiasis 14 5.0 5.1 signal
198 Cerebral Infarction 254 5.0 5.0 signal
199 Chest Pain 1,871 4.9 5.0 signal
200 Wisdom Teeth Removal 13 4.8 4.8 signal
201 Cerebrovascular Accident 1,686 4.8 4.9 signal
202 Hormone Level Abnormal 47 4.7 4.7 signal
203 Flank Pain 91 4.7 4.7 signal
204 Affect Lability 94 4.7 4.7 signal
205 Mood Swings 308 4.6 4.7 signal
206 Aphagia 47 4.6 4.6 signal
207 Atelectasis 93 4.6 4.6 signal
208 Vasodilatation 24 4.6 4.6 signal
209 Generalised Anxiety Disorder 14 4.6 4.6 signal
210 Aortic Thrombosis 11 4.6 4.6 signal
211 Sensation Of Heaviness 37 4.5 4.5 signal
212 Uterine Haemorrhage 40 4.5 4.5 signal
213 Pancreatitis 495 4.5 4.5 signal
214 Vaginal Discharge 93 4.5 4.5 signal
215 Abdominal Pain Upper 1,898 4.4 4.6 signal
216 Epigastric Discomfort 36 4.4 4.4 signal
217 Hirsutism 12 4.3 4.3 signal
218 Visual Field Defect 64 4.3 4.3 signal
219 Colitis Ischaemic 59 4.2 4.2 signal
220 Intermenstrual Bleeding 45 4.2 4.2 signal
221 Cervical Dysplasia 19 4.2 4.2 signal
222 Libido Decreased 104 4.0 4.0 signal
223 Vascular Injury 12 4.0 4.0 signal
224 Oedema Peripheral 1,013 4.0 4.0 signal
225 Attention Deficit/hyperactivity Disorder 27 4.0 4.0 signal
226 Monoparesis 15 4.0 4.0 signal
227 Phlebitis 42 3.9 3.9 signal
228 Antiphospholipid Syndrome 13 3.9 3.9 signal
229 Transient Ischaemic Attack 271 3.8 3.9 signal
230 Dilatation Ventricular 17 3.8 3.8 signal
231 Lobar Pneumonia 15 3.8 3.8 signal
232 Menstruation Irregular 212 3.8 3.8 signal
233 Haemorrhagic Transformation Stroke 12 3.8 3.8 signal
234 Depression 1,822 3.8 4.0 signal
235 Sudden Hearing Loss 16 3.8 3.8 signal
236 Papilloedema 36 3.8 3.8 signal
237 Vein Disorder 40 3.8 3.8 signal
238 Embolism 66 3.8 3.8 signal
239 Coronary Artery Thrombosis 16 3.8 3.8 signal
240 Contraindication To Medical Treatment 12 3.8 3.8 signal
241 Smear Cervix Abnormal 11 3.7 3.7 signal
242 Product Monitoring Error 11 3.7 3.7 signal
243 Adjustment Disorder 10 3.7 3.7 signal
244 Panic Attack 279 3.7 3.7 signal
245 Lacunar Infarction 18 3.6 3.6 signal
246 Total Lung Capacity Decreased 12 3.6 3.6 signal
247 Gallbladder Operation 30 3.6 3.6 signal
248 Procedural Pain 206 3.6 3.6 signal
249 Mood Altered 202 3.6 3.6 signal
250 Dyspareunia 34 3.6 3.6 signal
251 Infertility 11 3.5 3.5 signal
252 Facial Paresis 26 3.5 3.5 signal
253 Breast Cyst 13 3.5 3.5 signal
254 Uterine Leiomyoma 53 3.5 3.5 signal
255 Physical Disability 32 3.4 3.4 signal
256 Brain Injury 70 3.3 3.3 signal
257 Psychiatric Symptom 51 3.3 3.3 signal
258 Dyspepsia 668 3.3 3.3 signal
259 Hepatic Mass 13 3.2 3.2 signal
260 Mitral Valve Prolapse 11 3.2 3.2 signal
261 Musculoskeletal Chest Pain 102 3.2 3.2 signal
262 Anxiety Disorder 22 3.1 3.1 signal
263 Appendicectomy 23 3.1 3.1 signal
264 Hypoxic-ischaemic Encephalopathy 17 3.1 3.1 signal
265 Ischaemic Stroke 115 3.1 3.1 signal
266 Monoplegia 28 3.1 3.1 signal
267 Abdominal Adhesions 20 3.0 3.0 signal
268 Atrial Thrombosis 13 3.0 3.0 signal
269 Conversion Disorder 12 3.0 3.0 signal
270 Abdominal Distension 643 3.0 3.0 signal
271 Learning Disorder 15 2.9 2.9 signal
272 Aphasia 186 2.9 3.0 signal
273 Menopausal Symptoms 14 2.9 2.9 signal
274 Abortion 18 2.9 2.9 signal
275 Costochondritis 10 2.9 2.9 signal
276 Migraine 571 2.9 2.9 signal
277 Erythema Nodosum 21 2.9 2.9 signal
278 Pelvic Pain 109 2.9 2.9 signal
279 Pain In Extremity 1,760 2.9 2.9 signal
280 Cardiac Discomfort 12 2.9 2.9 signal
281 Pancreatitis Chronic 14 2.9 2.9 signal
282 Hypertrichosis 11 2.8 2.8 signal
283 Appendicitis 54 2.8 2.8 signal
284 Infectious Mononucleosis 13 2.8 2.8 signal
285 Intracranial Pressure Increased 32 2.8 2.8 signal
286 Alopecia Areata 10 2.7 2.7 signal
287 Bipolar Disorder 62 2.7 2.7 signal
288 Irritable Bowel Syndrome 120 2.7 2.7 signal
289 Pre-existing Condition Improved 35 2.7 2.7 signal
290 Acne 419 2.6 2.6 signal
291 Visual Disturbance 32 2.6 2.6 signal
292 Intracranial Aneurysm 22 2.6 2.6 signal
293 Loss Of Libido 49 2.6 2.6 signal
294 Muscle Fatigue 23 2.6 2.6 signal
295 Sinus Tachycardia 77 2.6 2.6 signal
296 Exercise Tolerance Decreased 31 2.6 2.6 signal
297 Abortion Induced 50 2.5 2.5 signal
298 Reading Disorder 12 2.5 2.5 signal
299 Motion Sickness 10 2.5 2.5 signal
300 Mechanical Ventilation 10 2.5 2.5 signal
301 Cerebral Ischaemia 27 2.5 2.5 signal
302 Nervousness 271 2.5 2.5 signal
303 Abortion Spontaneous 205 2.4 2.4 signal
304 Clumsiness 14 2.4 2.4 signal
305 Tearfulness 22 2.4 2.4 signal
306 Breast Mass 34 2.4 2.4 signal
307 Acne Cystic 15 2.4 2.4 signal
308 Flatulence 280 2.4 2.4 signal
309 Personality Disorder 13 2.4 2.4 signal
310 Crying 179 2.3 2.4 signal
311 Unintended Pregnancy 51 2.3 2.3 signal
312 Local Swelling 86 2.3 2.3 signal
313 Motor Dysfunction 49 2.3 2.3 signal
314 Brain Oedema 61 2.3 2.3 signal
315 Emotional Disorder 146 2.3 2.3 signal
316 Activities Of Daily Living Impaired 94 2.2 2.2 signal
317 Panic Disorder 18 2.2 2.2 signal
318 Supraventricular Tachycardia 44 2.2 2.2 signal
319 Subarachnoid Haemorrhage 47 2.2 2.2 signal
320 Atrial Septal Defect 38 2.2 2.2 signal
321 Feeling Of Despair 21 2.2 2.2 signal
322 Pregnancy 91 2.2 2.2 signal
323 Pancreatic Disorder 22 2.1 2.1 signal
324 Panic Reaction 32 2.1 2.1 signal
325 Convulsion 257 2.1 2.1 signal
326 Gastrointestinal Injury 12 2.1 2.1 signal
327 Frustration 16 2.1 2.1 signal
328 Pulmonary Hypertension 92 2.1 2.1 signal
329 Peripheral Ischaemia 18 2.1 2.1 signal
330 Gastritis 115 2.1 2.1 signal
331 Affective Disorder 34 2.1 2.1 signal
332 Crohn's Disease 30 2.1 2.1 signal
333 Hypoaesthesia 646 2.1 2.1 signal
334 Vomiting 2,005 2.0 2.1 signal
335 Lactose Intolerance 11 2.0 2.0 signal
336 Cerebrovascular Disorder 13 2.0 2.0 signal
337 Abasia 106 2.0 2.0 signal
338 Nephrolithiasis 191 2.0 2.0 no signal
339 Palpitations 488 2.0 2.0 no signal
340 Grand Mal Convulsion 39 2.0 2.0 no signal
341 Lymphadenitis 10 2.0 2.0 no signal
342 Dyspnoea 2,336 2.0 2.0 no signal
343 No Adverse Event 730 2.0 2.0 no signal
344 Haemorrhagic Stroke 32 1.9 1.9 no signal
345 Weight Bearing Difficulty 11 1.9 1.9 no signal
346 Self-injurious Ideation 17 1.9 1.9 no signal
347 Pancreatitis Acute 90 1.9 1.9 no signal
348 Vaginal Infection 19 1.9 1.9 no signal
349 Impaired Work Ability 86 1.9 1.9 no signal
350 Poor Peripheral Circulation 17 1.9 1.9 no signal
351 Inflammatory Bowel Disease 39 1.9 1.9 no signal
352 Major Depression 29 1.9 1.9 no signal
353 Blindness Transient 29 1.9 1.9 no signal
354 Hysterectomy 34 1.9 1.9 no signal
355 Hepatic Steatosis 73 1.9 1.9 no signal
356 Gastric Disorder 135 1.9 1.9 no signal
357 Coeliac Disease 38 1.9 1.9 no signal
358 Groin Pain 34 1.8 1.8 no signal
359 Premature Labour 22 1.8 1.8 no signal
360 Thyroid Function Test Abnormal 16 1.8 1.8 no signal
361 Pre-eclampsia 18 1.8 1.8 no signal
362 Hyperventilation 22 1.8 1.8 no signal
363 Haemoptysis 105 1.8 1.8 no signal
364 Hepatic Lesion 16 1.8 1.8 no signal
365 Nausea 2,903 1.8 1.8 no signal
366 Peripheral Arterial Occlusive Disease 15 1.7 1.7 no signal
367 Haemorrhage Subcutaneous 13 1.7 1.7 no signal
368 Speech Disorder 190 1.7 1.7 no signal
369 Tension 22 1.7 1.7 no signal
370 Endotracheal Intubation 10 1.7 1.7 no signal
371 Musculoskeletal Pain 187 1.7 1.7 no signal
372 Stress 253 1.7 1.7 no signal
373 Syncope 350 1.7 1.7 no signal
374 Depressed Mood 184 1.7 1.7 no signal
375 Partial Seizures 18 1.7 1.7 no signal
376 Blindness Unilateral 49 1.7 1.7 no signal
377 Dysarthria 130 1.7 1.7 no signal
378 Hearing Impaired 21 1.7 1.7 no signal
379 Dysphemia 15 1.6 1.6 no signal
380 Depressive Symptom 12 1.6 1.6 no signal
381 Chest Discomfort 348 1.6 1.6 no signal
382 Skin Discolouration 155 1.6 1.6 no signal
383 Antinuclear Antibody Positive 11 1.6 1.6 no signal
384 Vulvovaginal Pain 16 1.6 1.6 no signal
385 Coordination Abnormal 47 1.6 1.6 no signal
386 Blood Potassium Increased 54 1.6 1.6 no signal
387 Anger 113 1.6 1.6 no signal
388 Gastrointestinal Disorder 291 1.6 1.6 no signal
389 Weight Loss Poor 15 1.6 1.6 no signal
390 Loss Of Employment 10 1.6 1.6 no signal
391 Carotid Artery Occlusion 12 1.6 1.6 no signal
392 Circulatory Collapse 56 1.6 1.6 no signal
393 Duodenitis 10 1.6 1.6 no signal
394 Supraventricular Extrasystoles 11 1.6 1.6 no signal
395 Hypoaesthesia Oral 49 1.6 1.6 no signal
396 Hepatic Cyst 11 1.5 1.5 no signal
397 Arrhythmia 154 1.5 1.5 no signal
398 Vitamin B12 Deficiency 13 1.5 1.5 no signal
399 Irritability 194 1.5 1.5 no signal
400 Drug Exposure During Pregnancy 111 1.5 1.5 no signal
401 Photophobia 60 1.5 1.5 no signal
402 Hyperacusis 12 1.5 1.5 no signal
403 Food Poisoning 17 1.5 1.5 no signal
404 Anal Fissure 17 1.5 1.5 no signal
405 Heart Rate Irregular 72 1.5 1.5 no signal
406 Tenderness 33 1.5 1.5 no signal
407 Back Pain 734 1.5 1.5 no signal
408 Gastroenteritis 46 1.5 1.5 no signal
409 Heavy Menstrual Bleeding 25 1.5 1.5 no signal
410 Lung Infiltration 28 1.5 1.5 no signal
411 Communication Disorder 12 1.5 1.5 no signal
412 Suicidal Behaviour 13 1.5 1.5 no signal
413 Gastrointestinal Pain 34 1.5 1.5 no signal
414 Intestinal Ischaemia 17 1.5 1.5 no signal
415 Gastrooesophageal Reflux Disease 248 1.5 1.5 no signal
416 Tonsillitis 16 1.5 1.5 no signal
417 Caesarean Section 36 1.5 1.5 no signal
418 Cyanosis 48 1.5 1.5 no signal
419 Food Allergy 23 1.5 1.5 no signal
420 Hepatomegaly 30 1.5 1.5 no signal
421 Tension Headache 13 1.4 1.4 no signal
422 Pyelonephritis 26 1.4 1.4 no signal
423 Weight Increased 671 1.4 1.4 no signal
424 Paranoia 52 1.4 1.4 no signal
425 Personality Change 28 1.4 1.4 no signal
426 Seborrhoea 11 1.4 1.4 no signal
427 Diplopia 77 1.4 1.4 no signal
428 Dyspnoea Exertional 111 1.4 1.4 no signal
429 Suicidal Ideation 271 1.4 1.4 no signal
430 Vulvovaginal Discomfort 13 1.4 1.4 no signal
431 Coagulopathy 49 1.4 1.4 no signal
432 Cognitive Disorder 137 1.4 1.4 no signal
433 Amnesia 189 1.4 1.4 no signal
434 Sensory Loss 23 1.4 1.4 no signal
435 Anorexia 37 1.4 1.4 no signal
436 Pulmonary Fibrosis 54 1.3 1.3 no signal
437 Small For Dates Baby 14 1.3 1.3 no signal
438 Maternal Exposure Before Pregnancy 19 1.3 1.3 no signal
439 Tachycardia 247 1.3 1.3 no signal
440 Cerebral Haemorrhage 99 1.3 1.3 no signal
441 Blood Triglycerides Increased 49 1.3 1.3 no signal
442 Social Avoidant Behaviour 16 1.3 1.3 no signal
443 Hypertriglyceridaemia 16 1.3 1.3 no signal
444 Product Administration Interrupted 21 1.3 1.3 no signal
445 Obsessive-compulsive Disorder 22 1.3 1.3 no signal
446 Photopsia 17 1.3 1.3 no signal
447 Pharyngitis Streptococcal 29 1.3 1.3 no signal
448 Stomach Discomfort 14 1.3 1.3 no signal
449 Angina Pectoris 77 1.3 1.3 no signal
450 Jaundice 72 1.3 1.3 no signal
451 Disturbance In Attention 144 1.3 1.3 no signal
452 Muscle Tightness 43 1.3 1.3 no signal
453 Limb Discomfort 82 1.3 1.3 no signal
454 Food Craving 13 1.3 1.3 no signal
455 Iron Deficiency Anaemia 24 1.2 1.2 no signal
456 Headache 1,626 1.2 1.2 no signal
457 Ventricular Extrasystoles 27 1.2 1.2 no signal
458 Cholangitis 16 1.2 1.2 no signal
459 Skin Warm 15 1.2 1.2 no signal
460 Vulvovaginal Pruritus 13 1.2 1.2 no signal
461 Discomfort 156 1.2 1.2 no signal
462 Acute Myocardial Infarction 75 1.2 1.2 no signal
463 Pulse Absent 12 1.2 1.2 no signal
464 Paralysis 36 1.2 1.2 no signal
465 Increased Appetite 47 1.2 1.2 no signal
466 Muscle Spasms 452 1.2 1.2 no signal
467 Infarction 17 1.2 1.2 no signal
468 Faecal Incontinence 12 1.2 1.2 no signal
469 Goitre 10 1.2 1.2 no signal
470 Normal Newborn 13 1.1 1.1 no signal
471 Eating Disorder 51 1.1 1.1 no signal
472 Myocardial Infarction 418 1.1 1.1 no signal
473 Gastroenteritis Viral 43 1.1 1.1 no signal
474 Petit Mal Epilepsy 12 1.1 1.1 no signal
475 Product Prescribing Issue 48 1.1 1.1 no signal
476 Kidney Infection 46 1.1 1.1 no signal
477 Abnormal Sensation In Eye 10 1.1 1.1 no signal
478 Pneumothorax 37 1.1 1.1 no signal
479 Pleural Effusion 142 1.1 1.1 no signal
480 Ocular Icterus 10 1.1 1.1 no signal
481 Night Sweats 74 1.1 1.1 no signal
482 Defaecation Urgency 16 1.1 1.1 no signal
483 Extrasystoles 16 1.1 1.1 no signal
484 Presyncope 55 1.1 1.1 no signal
485 Dysgraphia 15 1.1 1.1 no signal
486 Dissociation 17 1.1 1.1 no signal
487 Peripheral Coldness 31 1.1 1.1 no signal
488 Blood Disorder 18 1.1 1.1 no signal
489 Haemorrhagic Anaemia 10 1.1 1.1 no signal
490 Facial Pain 20 1.1 1.1 no signal
491 Cheilitis 12 1.1 1.1 no signal
492 Tachypnoea 30 1.1 1.1 no signal
493 Decreased Interest 13 1.1 1.1 no signal
494 Tongue Disorder 16 1.0 1.0 no signal
495 Optic Neuritis 20 1.0 1.0 no signal
496 Cardiac Murmur 19 1.0 1.0 no signal
497 Loss Of Consciousness 279 1.0 1.0 no signal
498 Galactorrhoea 14 1.0 1.0 no signal
499 Hunger 29 1.0 1.0 no signal
500 Cold Sweat 38 1.0 1.0 no signal
501 Nerve Injury 24 1.0 1.0 no signal
502 Appetite Disorder 14 1.0 1.0 no signal
503 Post Procedural Haemorrhage 25 1.0 1.0 no signal
504 Angiopathy 12 1.0 1.0 no signal
505 Parosmia 16 1.0 1.0 no signal
506 Right Ventricular Failure 15 1.0 1.0 no signal
507 Peripheral Vascular Disorder 11 1.0 1.0 no signal
508 Blood Prolactin Increased 10 1.0 1.0 no signal
509 Peroneal Nerve Palsy 12 1.0 1.0 no signal
510 Inappropriate Schedule Of Drug Administration 152 1.0 1.0 no signal
511 Paraesthesia 332 1.0 1.0 no signal
512 Heart Rate Increased 208 1.0 1.0 no signal
513 Hiatus Hernia 27 1.0 1.0 no signal
514 Maternal Drugs Affecting Foetus 16 1.0 1.0 no signal
515 Ear Discomfort 21 1.0 1.0 no signal
516 Eye Movement Disorder 14 1.0 1.0 no signal
517 Hydrocephalus 11 1.0 1.0 no signal
518 Sinus Headache 12 1.0 1.0 no signal
519 Visual Acuity Reduced 67 1.0 1.0 no signal
520 Alopecia 388 0.9 0.9 no signal
521 Bowel Movement Irregularity 15 0.9 0.9 no signal
522 Impaired Gastric Emptying 25 0.9 0.9 no signal
523 Cardiovascular Disorder 50 0.9 0.9 no signal
524 Dizziness 965 0.9 0.9 no signal
525 Neurological Symptom 11 0.9 0.9 no signal
526 Muscular Weakness 220 0.9 0.9 no signal
527 Impaired Driving Ability 22 0.9 0.9 no signal
528 Cyst 24 0.9 0.9 no signal
529 Thinking Abnormal 36 0.9 0.9 no signal
530 Hyperlipidaemia 23 0.9 0.9 no signal
531 Ventricular Septal Defect 11 0.9 0.9 no signal
532 Mental Impairment 46 0.9 0.9 no signal
533 Neck Pain 106 0.9 0.9 no signal
534 Gastrointestinal Motility Disorder 10 0.9 0.9 no signal
535 Multiple Injuries 12 0.9 0.9 no signal
536 Mobility Decreased 134 0.9 0.9 no signal
537 Formication 13 0.9 0.9 no signal
538 Constipation 402 0.9 0.9 no signal
539 Pharyngolaryngeal Pain 10 0.9 0.9 no signal
540 Muscle Strain 16 0.9 0.9 no signal
541 Vision Blurred 253 0.9 0.9 no signal
542 Pharyngitis 23 0.9 0.9 no signal
543 Vertigo 112 0.9 0.9 no signal
544 Type 1 Diabetes Mellitus 11 0.9 0.9 no signal
545 Sleep Apnoea Syndrome 35 0.9 0.9 no signal
546 Diarrhoea 1,174 0.9 0.9 no signal
547 Deafness Unilateral 10 0.9 0.9 no signal
548 Hyperaesthesia 15 0.9 0.9 no signal
549 Concussion 14 0.9 0.9 no signal
550 Splenomegaly 21 0.9 0.9 no signal
551 Blindness 73 0.9 0.9 no signal
552 Fungal Infection 59 0.8 0.8 no signal
553 Dizziness Postural 17 0.8 0.8 no signal
554 Drug Dose Omission 294 0.8 0.8 no signal
555 Haemorrhage Intracranial 26 0.8 0.8 no signal
556 Visual Impairment 212 0.8 0.8 no signal
557 Dysstasia 50 0.8 0.8 no signal
558 Epilepsy 52 0.8 0.8 no signal
559 Procedural Complication 13 0.8 0.8 no signal
560 Respiratory Rate Increased 15 0.8 0.8 no signal
561 Thirst 30 0.8 0.8 no signal
562 Unevaluable Event 127 0.8 0.8 no signal
563 Lip Dry 15 0.8 0.8 no signal
564 Pulmonary Haemorrhage 13 0.8 0.8 no signal
565 Pallor 45 0.8 0.8 no signal
566 Swelling 154 0.8 0.8 no signal
567 Tricuspid Valve Incompetence 13 0.8 0.8 no signal
568 Photosensitivity Reaction 27 0.8 0.8 no signal
569 Chromaturia 37 0.8 0.8 no signal
570 Eructation 31 0.8 0.8 no signal
571 Pigmentation Disorder 10 0.8 0.8 no signal
572 Premature Baby 49 0.8 0.8 no signal
573 Thyroid Disorder 25 0.8 0.8 no signal
574 Feeling Hot 99 0.8 0.8 no signal
575 Sensory Disturbance 26 0.8 0.8 no signal
576 Renal Pain 17 0.8 0.8 no signal
577 Tendonitis 25 0.8 0.8 no signal
578 Diarrhoea Haemorrhagic 15 0.8 0.8 no signal
579 Apathy 23 0.8 0.8 no signal
580 Insomnia 422 0.8 0.8 no signal
581 Mydriasis 20 0.7 0.7 no signal
582 Lymphadenopathy 55 0.7 0.7 no signal
583 Colitis Ulcerative 69 0.7 0.7 no signal
584 Retinal Haemorrhage 11 0.7 0.7 no signal
585 Cardiac Flutter 10 0.7 0.7 no signal
586 Haematemesis 39 0.7 0.7 no signal
587 Abdominal Discomfort 256 0.7 0.7 no signal
588 Asthenia 572 0.7 0.7 no signal
589 Uterine Perforation 13 0.7 0.7 no signal
590 Pulmonary Congestion 20 0.7 0.7 no signal
591 Retching 32 0.7 0.7 no signal
592 Hyperhidrosis 194 0.7 0.7 no signal
593 Nervous System Disorder 47 0.7 0.7 no signal
594 Decreased Activity 16 0.7 0.7 no signal
595 Nephropathy 14 0.7 0.7 no signal
596 Hydronephrosis 11 0.7 0.7 no signal
597 General Physical Condition Abnormal 10 0.7 0.7 no signal
598 Lung Disorder 72 0.7 0.7 no signal
599 Sinusitis 151 0.7 0.7 no signal
600 Rash Papular 33 0.7 0.7 no signal
601 Polyuria 12 0.7 0.7 no signal
602 Oesophagitis 16 0.7 0.7 no signal
603 Liver Injury 35 0.7 0.7 no signal
604 Central Nervous System Lesion 20 0.7 0.7 no signal
605 Large Intestine Polyp 10 0.7 0.7 no signal
606 Product Substitution Issue 83 0.7 0.7 no signal
607 Blood Cholesterol Increased 67 0.7 0.7 no signal
608 Haematochezia 79 0.7 0.7 no signal
609 Muscle Atrophy 18 0.7 0.7 no signal
610 Bladder Disorder 14 0.7 0.7 no signal
611 Fibromyalgia 34 0.7 0.7 no signal
612 Musculoskeletal Discomfort 24 0.7 0.7 no signal
613 Pollakiuria 58 0.7 0.7 no signal
614 Hyperthyroidism 20 0.7 0.7 no signal
615 Gait Disturbance 265 0.7 0.7 no signal
616 Initial Insomnia 14 0.7 0.7 no signal
617 Fatigue 1,065 0.7 0.6 no signal
618 Body Temperature Increased 28 0.7 0.7 no signal
619 Hot Flush 103 0.7 0.7 no signal
620 Rhinitis 11 0.7 0.7 no signal
621 Feeling Cold 38 0.6 0.6 no signal
622 Poor Quality Sleep 29 0.6 0.6 no signal
623 Ataxia 16 0.6 0.6 no signal
624 Muscle Twitching 31 0.6 0.6 no signal
625 Feeling Abnormal 320 0.6 0.6 no signal
626 Haemorrhoids 26 0.6 0.6 no signal
627 Internal Haemorrhage 15 0.6 0.6 no signal
628 Urinary Tract Infection 222 0.6 0.6 no signal
629 Rash Generalised 34 0.6 0.6 no signal
630 Muscle Spasticity 16 0.6 0.6 no signal
631 Ear Pain 25 0.6 0.6 no signal
632 Pharyngeal Oedema 20 0.6 0.6 no signal
633 Sluggishness 13 0.6 0.6 no signal
634 Abnormal Behaviour 51 0.6 0.6 no signal
635 Pruritus Generalised 28 0.6 0.6 no signal
636 Weight Decreased 356 0.6 0.6 no signal
637 Colitis 48 0.6 0.6 no signal
638 Liver Function Test Abnormal 37 0.6 0.6 no signal
639 Gastric Ulcer 24 0.6 0.6 no signal
640 Throat Tightness 34 0.6 0.6 no signal
641 Ventricular Fibrillation 14 0.6 0.6 no signal
642 Paraesthesia Oral 18 0.6 0.6 no signal
643 Post Procedural Complication 24 0.6 0.6 no signal
644 Therapeutic Response Unexpected 56 0.6 0.6 no signal
645 Fluid Retention 63 0.6 0.6 no signal
646 Thyroid Cancer 15 0.6 0.6 no signal
647 Oedema 67 0.6 0.6 no signal
648 Cardiac Arrest 102 0.6 0.6 no signal
649 Haematoma 32 0.6 0.6 no signal
650 Memory Impairment 169 0.6 0.6 no signal
651 Delusion 19 0.6 0.6 no signal
652 Sleep Disorder 85 0.6 0.6 no signal
653 Hepatic Function Abnormal 45 0.6 0.6 no signal
654 Cardiomegaly 15 0.6 0.6 no signal
655 Seasonal Allergy 17 0.6 0.6 no signal
656 Pericarditis 20 0.6 0.6 no signal
657 Liver Disorder 53 0.6 0.6 no signal
658 Medication Error 66 0.6 0.6 no signal
659 Cystitis 38 0.6 0.6 no signal
660 Cardio-respiratory Arrest 50 0.6 0.6 no signal
661 Hair Texture Abnormal 16 0.6 0.6 no signal
662 Rectal Haemorrhage 51 0.6 0.6 no signal
663 Eyelid Ptosis 12 0.6 0.6 no signal
664 Nightmare 41 0.6 0.6 no signal
665 Facial Paralysis 10 0.6 0.6 no signal
666 Tinnitus 54 0.6 0.6 no signal
667 Eye Swelling 43 0.6 0.6 no signal
668 Disability 23 0.6 0.6 no signal
669 Contraindicated Product Administered 35 0.6 0.6 no signal
670 Eye Pain 64 0.6 0.6 no signal
671 Disorientation 46 0.6 0.6 no signal
672 Angioedema 51 0.6 0.6 no signal
673 Immunodeficiency 17 0.6 0.6 no signal
674 Laceration 11 0.5 0.5 no signal
675 Hypersomnia 33 0.5 0.5 no signal
676 Weight Fluctuation 12 0.5 0.5 no signal
677 Dry Eye 55 0.5 0.5 no signal
678 Hepatitis 29 0.5 0.5 no signal
679 Oral Herpes 22 0.5 0.5 no signal
680 Urticaria 188 0.5 0.5 no signal
681 Middle Insomnia 21 0.5 0.5 no signal
682 Vitamin D Deficiency 11 0.5 0.5 no signal
683 Hypertension 239 0.5 0.5 no signal
684 Oropharyngeal Pain 104 0.5 0.5 no signal
685 Vasculitis 13 0.5 0.5 no signal
686 Myositis 10 0.5 0.5 no signal
687 Dysuria 41 0.5 0.5 no signal
688 Lupus-like Syndrome 10 0.5 0.5 no signal
689 Cholestasis 21 0.5 0.5 no signal
690 Drug Administration Error 34 0.5 0.5 no signal
691 Hyperkalaemia 38 0.5 0.5 no signal
692 Tremor 180 0.5 0.5 no signal
693 Malnutrition 12 0.5 0.5 no signal
694 Mental Status Changes 30 0.5 0.5 no signal
695 Helicobacter Infection 11 0.5 0.5 no signal
696 Exposure During Pregnancy 67 0.5 0.5 no signal
697 Balance Disorder 93 0.5 0.5 no signal
698 Hypothyroidism 34 0.5 0.5 no signal
699 Pharmaceutical Product Complaint 28 0.5 0.5 no signal
700 Skin Disorder 35 0.5 0.5 no signal
701 Leukocytosis 19 0.5 0.5 no signal
702 Hereditary Angioedema 11 0.5 0.5 no signal
703 Serotonin Syndrome 20 0.5 0.5 no signal
704 Lethargy 60 0.5 0.5 no signal
705 Impaired Quality Of Life 15 0.5 0.5 no signal
706 Abnormal Weight Gain 13 0.5 0.5 no signal
707 Restlessness 38 0.5 0.5 no signal
708 Aggression 52 0.5 0.5 no signal
709 Limb Injury 28 0.5 0.5 no signal
710 Chills 121 0.5 0.5 no signal
711 Eyelid Oedema 12 0.5 0.5 no signal
712 Psychotic Disorder 30 0.5 0.5 no signal
713 Laryngitis 11 0.5 0.5 no signal
714 Haemorrhage 105 0.5 0.5 no signal
715 Frequent Bowel Movements 27 0.5 0.5 no signal
716 Hypotonia 10 0.5 0.5 no signal
717 Blood Pressure Decreased 66 0.5 0.5 no signal
718 Feeling Jittery 19 0.5 0.5 no signal
719 Nocturia 12 0.5 0.5 no signal
720 Coma 47 0.5 0.5 no signal
721 Malaise 433 0.5 0.5 no signal
722 Somnolence 198 0.5 0.5 no signal
723 Peripheral Swelling 151 0.5 0.5 no signal
724 Erythema 201 0.5 0.5 no signal
725 Small Intestinal Obstruction 12 0.5 0.5 no signal
726 Fistula 11 0.5 0.5 no signal
727 Withdrawal Syndrome 41 0.5 0.5 no signal
728 Respiratory Arrest 27 0.5 0.5 no signal
729 Dermatitis Contact 11 0.5 0.5 no signal
730 Injection Site Discolouration 12 0.5 0.5 no signal
731 Contusion 93 0.5 0.5 no signal
732 Psychomotor Hyperactivity 16 0.5 0.5 no signal
733 Burning Sensation 67 0.5 0.5 no signal
734 Deafness 25 0.5 0.5 no signal
735 Head Injury 30 0.5 0.5 no signal
736 Foot Fracture 18 0.5 0.5 no signal
737 Off Label Use 820 0.5 0.4 no signal
738 Ulcer 15 0.4 0.4 no signal
739 Hypoxia 33 0.4 0.4 no signal
740 Musculoskeletal Stiffness 82 0.4 0.4 no signal
741 Respiratory Disorder 28 0.4 0.4 no signal
742 Road Traffic Accident 39 0.4 0.4 no signal
743 Pyrexia 322 0.4 0.4 no signal
744 Product Use In Unapproved Indication 227 0.4 0.4 no signal
745 Respiratory Tract Infection 24 0.4 0.4 no signal
746 Vitreous Floaters 9 0.4 0.4 no signal
747 Decreased Appetite 212 0.4 0.4 no signal
748 Embedded Device 9 0.4 0.4 no signal
749 Blood Pressure Increased 140 0.4 0.4 no signal
750 Confusional State 147 0.4 0.4 no signal
751 Dental Caries 10 0.4 0.4 no signal
752 Cough 253 0.4 0.4 no signal
753 Ear Infection 24 0.4 0.4 no signal
754 Joint Range Of Motion Decreased 12 0.4 0.4 no signal
755 Eye Haemorrhage 12 0.4 0.4 no signal
756 Ileus 11 0.4 0.4 no signal
757 Intentional Self-injury 18 0.4 0.4 no signal
758 Swelling Face 58 0.4 0.4 no signal
759 No Therapeutic Response 11 0.4 0.4 no signal
760 Sinus Congestion 12 0.4 0.4 no signal
761 Dehydration 118 0.4 0.4 no signal
762 Mitral Valve Incompetence 10 0.4 0.4 no signal
763 Micturition Urgency 10 0.4 0.4 no signal
764 Surgery 51 0.4 0.4 no signal
765 Akathisia 12 0.4 0.4 no signal
766 Intentional Dose Omission 24 0.4 0.4 no signal
767 Obesity 14 0.4 0.4 no signal
768 Lip Swelling 29 0.4 0.4 no signal
769 Joint Swelling 105 0.4 0.4 no signal
770 Brain Neoplasm 8 0.4 0.4 no signal
771 Hepatic Enzyme Increased 59 0.4 0.4 no signal
772 Increased Tendency To Bruise 8 0.4 0.4 no signal
773 Unresponsive To Stimuli 22 0.4 0.4 no signal
774 Stevens-johnson Syndrome 19 0.4 0.4 no signal
775 Disseminated Intravascular Coagulation 12 0.4 0.4 no signal
776 Ventricular Tachycardia 14 0.4 0.4 no signal
777 Ankylosing Spondylitis 11 0.4 0.4 no signal
778 Economic Problem 13 0.4 0.4 no signal
779 Joint Injury 18 0.4 0.4 no signal
780 Intentional Product Use Issue 74 0.4 0.4 no signal
781 Myalgia 143 0.4 0.4 no signal
782 Cardiogenic Shock 12 0.4 0.4 no signal
783 Drug Dispensing Error 13 0.4 0.4 no signal
784 Autoimmune Disorder 8 0.4 0.4 no signal
785 Tooth Infection 11 0.4 0.4 no signal
786 Bronchitis 62 0.4 0.4 no signal
787 Respiratory Distress 23 0.4 0.4 no signal
788 Shock 19 0.4 0.4 no signal
789 Hernia 16 0.4 0.4 no signal
790 Cardiac Disorder 78 0.4 0.4 no signal
791 Agitation 61 0.4 0.4 no signal
792 Lung Infection 13 0.4 0.4 no signal
793 Neuralgia 20 0.4 0.4 no signal
794 Dysphagia 78 0.4 0.4 no signal
795 Intervertebral Disc Protrusion 18 0.4 0.4 no signal
796 Systemic Lupus Erythematosus 29 0.4 0.4 no signal
797 Product Dose Omission In Error 22 0.4 0.4 no signal
798 Dyskinesia 33 0.4 0.4 no signal
799 Premature Delivery 13 0.4 0.4 no signal
800 Red Blood Cell Sedimentation Rate Increased 9 0.4 0.4 no signal
801 Ligament Sprain 8 0.4 0.4 no signal
802 Acute Hepatic Failure 11 0.4 0.4 no signal
803 Sinus Disorder 16 0.4 0.4 no signal
804 Suicide Attempt 49 0.4 0.4 no signal
805 Maternal Exposure During Pregnancy 71 0.4 0.4 no signal
806 Eye Infection 9 0.4 0.4 no signal
807 Injection Site Extravasation 10 0.4 0.4 no signal
808 Dermatitis Atopic 40 0.4 0.4 no signal
809 Inflammation 41 0.4 0.4 no signal
810 C-reactive Protein Increased 29 0.4 0.4 no signal
811 Eczema 40 0.4 0.4 no signal
812 Head Discomfort 14 0.4 0.4 no signal
813 Cellulitis 40 0.4 0.4 no signal
814 Mania 13 0.4 0.4 no signal
815 Blood Urine Present 15 0.4 0.4 no signal
816 Influenza Like Illness 65 0.4 0.4 no signal
817 Drug Level Decreased 8 0.4 0.4 no signal
818 Candida Infection 13 0.4 0.4 no signal
819 White Blood Cell Count Increased 30 0.4 0.4 no signal
820 Intraocular Pressure Increased 10 0.4 0.4 no signal
821 Euphoric Mood 8 0.4 0.4 no signal
822 Blood Bilirubin Increased 21 0.4 0.4 no signal
823 Blood Potassium Decreased 23 0.4 0.4 no signal
824 Dysgeusia 57 0.4 0.4 no signal
825 Eye Disorder 25 0.4 0.4 no signal
826 Drug Interaction 121 0.4 0.4 no signal
827 Epistaxis 57 0.4 0.4 no signal
828 Adverse Event 70 0.4 0.4 no signal
829 Upper Respiratory Tract Infection 35 0.4 0.4 no signal
830 Asthma 85 0.4 0.4 no signal
831 Blood Thyroid Stimulating Hormone Increased 7 0.4 0.4 no signal
832 Abnormal Dreams 21 0.4 0.4 no signal
833 Incontinence 8 0.4 0.4 no signal
834 Hypophagia 19 0.4 0.4 no signal
835 Sudden Death 8 0.4 0.4 no signal
836 Rash Erythematous 35 0.4 0.4 no signal
837 Rash Macular 26 0.4 0.4 no signal
838 Renal Failure Acute 32 0.4 0.4 no signal
839 Anaphylactic Shock 19 0.4 0.4 no signal
840 Back Injury 8 0.4 0.4 no signal
841 Pericardial Effusion 17 0.4 0.4 no signal
842 Ocular Discomfort 8 0.4 0.4 no signal
843 Product Packaging Quantity Issue 8 0.3 0.3 no signal
844 Gingival Bleeding 10 0.3 0.3 no signal
845 Hepatic Failure 22 0.3 0.3 no signal
846 Dermatitis 15 0.3 0.3 no signal
847 Dermatitis Allergic 9 0.3 0.3 no signal
848 Renal Tubular Necrosis 7 0.3 0.3 no signal
849 Arthralgia 294 0.3 0.3 no signal
850 Pain In Jaw 20 0.3 0.3 no signal
851 Rash 304 0.3 0.3 no signal
852 Impaired Healing 23 0.3 0.3 no signal
853 Myocardial Ischaemia 8 0.3 0.3 no signal
854 Infusion Related Reaction 46 0.3 0.3 no signal
855 Altered State Of Consciousness 15 0.3 0.3 no signal
856 Dry Throat 7 0.3 0.3 no signal
857 Orthostatic Hypotension 12 0.3 0.3 no signal
858 Temperature Intolerance 7 0.3 0.3 no signal
859 Renal Disorder 32 0.3 0.3 no signal
860 Eye Discharge 7 0.3 0.3 no signal
861 Respiratory Failure 50 0.3 0.3 no signal
862 Depressed Level Of Consciousness 27 0.3 0.3 no signal
863 Injection Site Haematoma 10 0.3 0.3 no signal
864 Drug-induced Liver Injury 21 0.3 0.3 no signal
865 Acute Respiratory Failure 13 0.3 0.3 no signal
866 Aspartate Aminotransferase Increased 36 0.3 0.3 no signal
867 Accident 8 0.3 0.3 no signal
868 Sneezing 15 0.3 0.3 no signal
869 Incorrect Drug Administration Duration 19 0.3 0.3 no signal
870 Hypersensitivity 123 0.3 0.3 no signal
871 Seizure 76 0.3 0.3 no signal
872 Pneumonia 214 0.3 0.3 no signal
873 Injection Site Urticaria 16 0.3 0.3 no signal
874 Hypokalaemia 30 0.3 0.3 no signal
875 Conjunctivitis 12 0.3 0.3 no signal
876 Coronary Artery Occlusion 9 0.3 0.3 no signal
877 Hypomagnesaemia 9 0.3 0.3 no signal
878 Throat Irritation 29 0.3 0.3 no signal
879 Adverse Drug Reaction 58 0.3 0.3 no signal
880 Bacterial Infection 12 0.3 0.3 no signal
881 Aphonia 9 0.3 0.3 no signal
882 Ankle Fracture 10 0.3 0.3 no signal
883 Mass 9 0.3 0.3 no signal
884 Dry Mouth 52 0.3 0.3 no signal
885 Incorrect Product Administration Duration 13 0.3 0.3 no signal
886 Injection Site Nodule 7 0.3 0.3 no signal
887 Alanine Aminotransferase Increased 39 0.3 0.3 no signal
888 Poisoning 8 0.3 0.3 no signal
889 Injection Site Irritation 8 0.3 0.3 no signal
890 Viral Infection 21 0.3 0.3 no signal
891 Transaminases Increased 14 0.3 0.3 no signal
892 Anaemia 120 0.3 0.3 no signal
893 Hallucination, Auditory 10 0.3 0.3 no signal
894 Musculoskeletal Disorder 12 0.3 0.3 no signal
895 Subdural Haematoma 9 0.3 0.3 no signal
896 Heart Rate Decreased 22 0.3 0.3 no signal
897 Hallucination, Visual 13 0.3 0.3 no signal
898 Sinus Bradycardia 6 0.3 0.3 no signal
899 Mouth Ulceration 13 0.3 0.3 no signal
900 Nasopharyngitis 114 0.3 0.3 no signal
901 Decreased Immune Responsiveness 6 0.3 0.3 no signal
902 Platelet Count Increased 8 0.3 0.3 no signal
903 Generalised Tonic-clonic Seizure 10 0.3 0.3 no signal
904 Product Use Issue 114 0.3 0.3 no signal
905 Bedridden 8 0.3 0.3 no signal
906 Disease Recurrence 29 0.3 0.3 no signal
907 Neoplasm 7 0.3 0.3 no signal
908 Eye Pruritus 20 0.3 0.3 no signal
909 Pruritus 229 0.3 0.3 no signal
910 Body Temperature Decreased 6 0.3 0.3 no signal
911 Multiple Sclerosis 29 0.3 0.3 no signal
912 Feeding Disorder 12 0.3 0.3 no signal
913 Renal Injury 18 0.3 0.3 no signal
914 Wheezing 35 0.3 0.3 no signal
915 Muscle Rigidity 7 0.3 0.3 no signal
916 Hyperbilirubinaemia 6 0.3 0.3 no signal
917 Tooth Disorder 13 0.3 0.3 no signal
918 Extra Dose Administered 23 0.3 0.3 no signal
919 Oral Discomfort 8 0.3 0.3 no signal
920 Glaucoma 11 0.3 0.3 no signal
921 Treatment Noncompliance 31 0.3 0.3 no signal
922 Abscess 9 0.3 0.3 no signal
923 Movement Disorder 18 0.3 0.3 no signal
924 Sleep Disorder Due To A General Medical Condition 9 0.3 0.3 no signal
925 Eye Irritation 31 0.3 0.3 no signal
926 Toothache 10 0.3 0.3 no signal
927 Haematocrit Decreased 11 0.3 0.3 no signal
928 Pulmonary Arterial Hypertension 8 0.3 0.3 no signal
929 Infusion Site Pain 7 0.3 0.3 no signal
930 Anaphylactic Reaction 30 0.3 0.3 no signal
931 Ascites 16 0.3 0.3 no signal
932 Gait Inability 18 0.3 0.3 no signal
933 Swollen Tongue 17 0.3 0.3 no signal
934 Urinary Retention 18 0.3 0.3 no signal
935 Injection Site Induration 7 0.3 0.3 no signal
936 Wound 15 0.3 0.3 no signal
937 Product Availability Issue 12 0.3 0.3 no signal
938 Dysphonia 31 0.3 0.3 no signal
939 Arteriosclerosis 5 0.3 0.3 no signal
940 Myocarditis 6 0.3 0.3 no signal
941 Skin Fissures 10 0.3 0.3 no signal
942 Flushing 54 0.3 0.3 no signal
943 Influenza 59 0.3 0.3 no signal
944 Infection 76 0.3 0.2 no signal
945 Hallucination 39 0.2 0.2 no signal
946 Rash Pruritic 28 0.2 0.2 no signal
947 Uveitis 7 0.2 0.2 no signal
948 Wrong Technique In Drug Usage Process 19 0.2 0.2 no signal
949 Knee Operation 5 0.2 0.2 no signal
950 Sexual Dysfunction 6 0.2 0.2 no signal
951 Multi-organ Failure 9 0.2 0.2 no signal
952 Madarosis 6 0.2 0.2 no signal
953 Spinal Pain 6 0.2 0.2 no signal
954 Drug Eruption 9 0.2 0.2 no signal
955 Dry Skin 67 0.2 0.2 no signal
956 Blood Iron Decreased 6 0.2 0.2 no signal
957 Lymphocyte Count Decreased 9 0.2 0.2 no signal
958 Diabetes Mellitus 38 0.2 0.2 no signal
959 Injection Site Rash 15 0.2 0.2 no signal
960 Injection Site Erythema 61 0.2 0.2 no signal
961 Schizophrenia 6 0.2 0.2 no signal
962 Pulmonary Oedema 22 0.2 0.2 no signal
963 Productive Cough 23 0.2 0.2 no signal
964 Skin Haemorrhage 7 0.2 0.2 no signal
965 Petechiae 5 0.2 0.2 no signal
966 Lower Limb Fracture 9 0.2 0.2 no signal
967 Insurance Issue 7 0.2 0.2 no signal
968 Diverticulitis 13 0.2 0.2 no signal
969 Lacrimation Increased 14 0.2 0.2 no signal
970 Renal Failure 62 0.2 0.2 no signal
971 Choking 9 0.2 0.2 no signal
972 Multiple Sclerosis Relapse 32 0.2 0.2 no signal
973 Device Use Issue 8 0.2 0.2 no signal
974 Injection Site Swelling 35 0.2 0.2 no signal
975 Faeces Discoloured 10 0.2 0.2 no signal
976 Device Dislocation 20 0.2 0.2 no signal
977 Bone Pain 27 0.2 0.2 no signal
978 Eosinophilia 8 0.2 0.2 no signal
979 Joint Stiffness 12 0.2 0.2 no signal
980 Blood Pressure Abnormal 9 0.2 0.2 no signal
981 Rhinorrhoea 29 0.2 0.2 no signal
982 Ejection Fraction Decreased 7 0.2 0.2 no signal
983 Sopor 6 0.2 0.2 no signal
984 Drug Ineffective For Unapproved Indication 25 0.2 0.2 no signal
985 Breast Cancer Female 12 0.2 0.2 no signal
986 Drug Effective For Unapproved Indication 13 0.2 0.2 no signal
987 Respiratory Tract Congestion 7 0.2 0.2 no signal
988 Ageusia 11 0.2 0.2 no signal
989 Drug Withdrawal Syndrome 39 0.2 0.2 no signal
990 Restless Legs Syndrome 8 0.2 0.2 no signal
991 Product Dose Omission 29 0.2 0.2 no signal
992 Haematuria 15 0.2 0.2 no signal
993 Injection Site Warmth 9 0.2 0.2 no signal
994 Retinal Detachment 4 0.2 0.2 no signal
995 Drug Toxicity 6 0.2 0.2 no signal
996 Nerve Compression 4 0.2 0.2 no signal
997 Gastric Haemorrhage 5 0.2 0.2 no signal
998 Product Quality Issue 58 0.2 0.2 no signal
999 Erythema Multiforme 4 0.2 0.2 no signal
1000 Carpal Tunnel Syndrome 6 0.2 0.2 no signal
1001 Nasal Congestion 25 0.2 0.2 no signal
1002 Intestinal Obstruction 16 0.2 0.2 no signal
1003 Inappropriate Schedule Of Product Administration 75 0.2 0.2 no signal
1004 Leukaemia 4 0.2 0.2 no signal
1005 Eye Inflammation 4 0.2 0.2 no signal
1006 Spinal Disorder 4 0.2 0.2 no signal
1007 Myoclonus 5 0.2 0.2 no signal
1008 Covid-19 74 0.2 0.2 no signal
1009 Condition Aggravated 126 0.2 0.2 no signal
1010 Electrocardiogram Qt Prolonged 15 0.2 0.2 no signal
1011 Bradycardia 22 0.2 0.2 no signal
1012 Anosmia 6 0.2 0.2 no signal
1013 Face Oedema 7 0.2 0.2 no signal
1014 Cardiac Failure 33 0.2 0.2 no signal
1015 Drug Prescribing Error 8 0.2 0.2 no signal
1016 Blister 23 0.2 0.2 no signal
1017 Fall 136 0.2 0.2 no signal
1018 Arthritis 32 0.2 0.2 no signal
1019 Injection Site Pruritus 27 0.2 0.2 no signal
1020 Urinary Incontinence 12 0.2 0.2 no signal
1021 Hypotension 81 0.2 0.2 no signal
1022 Blood Alkaline Phosphatase Increased 10 0.2 0.2 no signal
1023 Tooth Extraction 5 0.2 0.2 no signal
1024 Salivary Hypersecretion 4 0.2 0.2 no signal
1025 Hair Colour Changes 5 0.2 0.2 no signal
1026 Oxygen Saturation Decreased 22 0.2 0.2 no signal
1027 Foetal Exposure During Pregnancy 32 0.2 0.2 no signal
1028 Injection Site Reaction 27 0.2 0.2 no signal
1029 Coronary Artery Disease 12 0.2 0.2 no signal
1030 Synovitis 7 0.2 0.2 no signal
1031 Injection Site Discomfort 4 0.2 0.2 no signal
1032 Ocular Hyperaemia 18 0.2 0.2 no signal
1033 Drug Effect Decreased 21 0.2 0.2 no signal
1034 Injection Site Bruising 30 0.2 0.2 no signal
1035 Transfusion 4 0.2 0.2 no signal
1036 Immune System Disorder 5 0.2 0.2 no signal
1037 Complication Associated With Device 5 0.2 0.2 no signal
1038 Intentional Drug Misuse 8 0.2 0.2 no signal
1039 Breast Cancer Metastatic 4 0.2 0.2 no signal
1040 Proteinuria 7 0.2 0.2 no signal
1041 Fracture 7 0.2 0.2 no signal
1042 Staphylococcal Infection 12 0.2 0.2 no signal
1043 Illness 36 0.2 0.2 no signal
1044 Hypertensive Crisis 4 0.2 0.2 no signal
1045 Drug Effect Less Than Expected 5 0.2 0.2 no signal
1046 Complication Of Device Removal 6 0.2 0.2 no signal
1047 Status Epilepticus 4 0.2 0.2 no signal
1048 Therapy Cessation 18 0.2 0.2 no signal
1049 Incorrect Dose Administered 79 0.2 0.2 no signal
1050 Product Dose Omission Issue 100 0.2 0.2 no signal
1051 Hypoglycaemia 17 0.2 0.2 no signal
1052 Ill-defined Disorder 21 0.2 0.2 no signal
1053 Injection Site Haemorrhage 27 0.2 0.2 no signal
1054 Breast Cancer 32 0.2 0.2 no signal
1055 Meningioma 5 0.2 0.2 no signal
1056 Skin Exfoliation 28 0.2 0.2 no signal
1057 Loss Of Personal Independence In Daily Activities 16 0.2 0.2 no signal
1058 Macular Degeneration 4 0.2 0.2 no signal
1059 Drug Intolerance 32 0.2 0.2 no signal
1060 Hyperglycaemia 12 0.2 0.2 no signal
1061 Injection Site Pain 99 0.2 0.2 no signal
1062 Product Packaging Issue 3 0.2 0.2 no signal
1063 Drug Ineffective 422 0.2 0.1 no signal
1064 Therapeutic Response Decreased 19 0.2 0.1 no signal
1065 Stomatitis 19 0.1 0.1 no signal
1066 Sedation 8 0.1 0.1 no signal
1067 Device Expulsion 20 0.1 0.1 no signal
1068 Adverse Reaction 4 0.1 0.1 no signal
1069 Product Physical Issue 6 0.1 0.1 no signal
1070 Injection Site Mass 11 0.1 0.1 no signal
1071 Malignant Melanoma 4 0.1 0.1 no signal
1072 Product Taste Abnormal 4 0.1 0.1 no signal
1073 Hospitalisation 45 0.1 0.1 no signal
1074 Diabetic Ketoacidosis 7 0.1 0.1 no signal
1075 Product Odour Abnormal 3 0.1 0.1 no signal
1076 Metastases To Liver 5 0.1 0.1 no signal
1077 Drug Hypersensitivity 55 0.1 0.1 no signal
1078 Diabetes Mellitus Inadequate Control 5 0.1 0.1 no signal
1079 Device Breakage 11 0.1 0.1 no signal
1080 Thrombocytopenia 31 0.1 0.1 no signal
1081 Herpes Zoster 16 0.1 0.1 no signal
1082 Renal Impairment 23 0.1 0.1 no signal
1083 Psoriatic Arthropathy 11 0.1 0.1 no signal
1084 Complication Of Device Insertion 5 0.1 0.1 no signal
1085 Circumstance Or Information Capable Of Leading To Medication Error 9 0.1 0.1 no signal
1086 Cardiac Failure Congestive 21 0.1 0.1 no signal
1087 Dystonia 5 0.1 0.1 no signal
1088 Hypoacusis 11 0.1 0.1 no signal
1089 Therapeutic Product Effect Incomplete 18 0.1 0.1 no signal
1090 Neuropathy Peripheral 24 0.1 0.1 no signal
1091 Skin Burning Sensation 18 0.1 0.1 no signal
1092 Therapeutic Response Shortened 8 0.1 0.1 no signal
1093 Arthropathy 14 0.1 0.1 no signal
1094 Rheumatoid Arthritis 28 0.1 0.1 no signal
1095 Atrial Fibrillation 24 0.1 0.1 no signal
1096 Application Site Irritation 3 0.1 0.1 no signal
1097 Psoriasis 31 0.1 0.1 no signal
1098 Intentional Overdose 15 0.1 0.1 no signal
1099 Haemoglobin Decreased 24 0.1 0.1 no signal
1100 Intentional Product Misuse 20 0.1 0.1 no signal
1101 Product Dispensing Error 5 0.1 0.1 no signal
1102 Device Issue 20 0.1 0.1 no signal
1103 Pain Of Skin 6 0.1 0.1 no signal
1104 Exposure Via Skin Contact 5 0.1 0.1 no signal
1105 Lower Respiratory Tract Infection 10 0.1 0.1 no signal
1106 Therapy Interrupted 15 0.1 0.1 no signal
1107 Hepatocellular Injury 3 0.1 0.1 no signal
1108 Gastrointestinal Haemorrhage 17 0.1 0.1 no signal
1109 Device Malfunction 13 0.1 0.1 no signal
1110 Product Preparation Error 4 0.1 0.1 no signal
1111 Application Site Erythema 5 0.1 0.1 no signal
1112 Sepsis 21 0.1 0.1 no signal
1113 Completed Suicide 15 0.1 0.1 no signal
1114 White Blood Cell Count Decreased 19 0.1 0.1 no signal
1115 Skin Irritation 8 0.1 0.1 no signal
1116 Syringe Issue 3 0.1 0.1 no signal
1117 Drug Effect Incomplete 6 0.1 0.1 no signal
1118 Wrong Technique In Product Usage Process 31 0.1 0.1 no signal
1119 Injury Associated With Device 3 0.1 0.1 no signal
1120 Device Use Error 5 0.1 0.1 no signal
1121 Treatment Failure 11 0.1 0.1 no signal
1122 Product Complaint 3 0.1 0.1 no signal
1123 Overdose 26 0.1 0.1 no signal
1124 Toxicity To Various Agents 19 0.1 0.1 no signal
1125 Tardive Dyskinesia 3 0.1 0.1 no signal
1126 Platelet Count Decreased 11 0.0 0.0 no signal
1127 Blood Glucose Increased 19 0.0 0.0 no signal
1128 Drug Dose Omission By Device 7 0.0 0.0 no signal
1129 Accidental Exposure To Product 9 0.0 0.0 no signal
1130 Death 71 0.0 0.0 no signal
1131 Drug Dependence 13 0.0 0.0 no signal
1132 Dependence 3 0.0 0.0 no signal
1133 Device Difficult To Use 3 0.0 0.0 no signal