Reaction

Cholecystitis Acute reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,582 reports · 358 co-occurring drugs

As of the last recalculation, Cholecystitis Acute appears in 5,582 FAERS reports alongside 358 co-occurring drug terms. The strongest observed disproportionality signal is DROSPIRENONE AND ETHINYL ESTRADIOL (PRR 114.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Drospirenone And Ethinyl Estradiol	1,095	114.7	117.6
Methylprednisolone Acetate	26	12.2	12.2
Lenvatinib	104	12.0	12.1
Promethazine Hydrochloride	53	10.7	10.8
Esomeprazole Magnesium Capsule, Delayed Release	41	10.6	10.6
Esomeprazole Magnesium Delayed Release Capsules	41	10.6	10.6
Esomeprazole Magnesium Dihydrate	41	10.6	10.6
Ibuprofen And Diphenhydramine Citrate	62	10.0	10.1
Diphenhydramine Hydrochloride Capsule, Liquid Filled	44	7.7	7.7
Teduglutide	27	7.5	7.5
Ceftriaxone Sodium	75	7.4	7.4
Piperacillin Sodium And Tazobactam Sodium	37	7.1	7.1
Vitamin E	59	7.1	7.1
Pegaspargase	23	7.0	7.0
Metronidazole	118	7.0	7.0
Ursodiol	40	6.9	6.9
Pitavastatin Calcium	18	6.6	6.6
Ursosiol	34	6.6	6.6
Hyoscyamine Sulfate	16	6.5	6.5
Febuxostat Tablets 40 Mg	17	6.2	6.3
Febuxostat Tablets 80 Mg	17	6.2	6.3
Posaconazole	27	6.2	6.2
Meperidine Hydrochloride	15	6.1	6.1
Cetirizine Hydrochloride Allergy	49	6.1	6.1
Cetirizine Hydrochloride Tablets	49	6.1	6.1
Rabeprazole Sodium	44	6.1	6.1
Dicyclomine Hydrochloride	23	6.0	6.0
Alemtuzumab	30	5.8	5.8
Everolimus Tablets	26	5.8	5.8
Posaconazole Delayed-Release	17	5.8	5.8
Olmesartan Medoxomil	55	5.8	5.8
Metronidazole Topical	71	5.6	5.6
Ceftriaxone	49	5.6	5.6
Cephalexin	32	5.5	5.5
Linezolid	43	5.4	5.4
Voriconazole Injection	31	5.3	5.4
Esomeprazole	86	5.2	5.2
Desloratadine	15	5.2	5.2
Voriconazole	41	5.1	5.1
Cimetidine	13	5.0	5.0
Goserelin	18	5.0	5.0
Ascorbic Acid	31	5.0	5.0
Azithromycin Dihydrate	77	4.9	5.0
Ciprofolxacin	91	4.8	4.8
Ciprofloxacin Tablets	91	4.8	4.8
Meropenem	41	4.8	4.8
Ciprofloxacin	116	4.8	4.8
Sunitinib Malate	50	4.8	4.8
Febuxostat	21	4.7	4.7
Ciprofloxacin Hydrochloride And Hydrocortisone	26	4.7	4.7
Amiodarone Hydrochloride	14	4.7	4.7
Abiraterone	17	4.7	4.7
Terbinafine Hydrochloride	11	4.6	4.6
Ciprofloxacin Hydrochloride	118	4.6	4.6
Gentamicin	16	4.6	4.6
Famotidine	141	4.6	4.6
Cefazolin	11	4.5	4.5
Atropine Sulfate	13	4.5	4.5
Elexacaftor, Tezacaftor, And Ivacaftor	15	4.5	4.5
Magnesium Oxide	50	4.5	4.5
Azithromycin	48	4.5	4.5
Rizatriptan Benzoate	12	4.4	4.4
Rabeprazole	26	4.4	4.4
Piperacillin Sodium,Tazobactam Sodium	31	4.4	4.4
Cefazolin Sodium	14	4.3	4.3
Azithromycin Monohydrate	48	4.3	4.3
Prochlorperazine	32	4.3	4.3
Lansoprazole	200	4.3	4.3
Magnesium Sulfate Heptahydrate	15	4.3	4.3
Amoxicillin And Clavulanate Potassium	31	4.3	4.3
Gentamicin Sulfate	18	4.3	4.3
Docusate Sodium - Sennosides	36	4.2	4.2
Ibuprofen Capsule	217	4.2	4.2
Ibuprofen Tablet, Film Coated	217	4.2	4.2
Ibupfrofen	217	4.2	4.2
Ibuprofen Tablets Usp, 200Mg	217	4.2	4.2
Ibuprofen Oral	217	4.2	4.2
Ibuprofen Capsules 200 Mg	217	4.2	4.2
Ibuprofen 200 Mg	217	4.2	4.2
Ibuprofen 200Mg	217	4.2	4.2
Metoclopramide Hydrochloride	85	4.2	4.2
Ibuprofen	288	4.1	4.1
Magnesium Sulfate In Water For	14	4.1	4.1
Enalapril	60	4.1	4.1
Bevacizumab	132	4.0	4.0
Pembrolizumab	112	4.0	4.0
Cholestyramine	13	4.0	4.0
Magnesium Sulfate	14	4.0	4.0
Loperamide Hydrochloride And Dimethicone	34	4.0	4.0
Lithium Carbonate	18	4.0	4.0
Ezetimibe And Simvastatin	16	3.9	3.9
Granisetron Hydrochloride	11	3.9	3.9
Enalapril Maleate	26	3.9	3.9
Losartan Potassium And Hydrochlorothiazide	12	3.9	3.9
Nitrofurantoin	17	3.9	3.9
Fexofenadine	17	3.8	3.8
Nitrofurantoin (Monohydrate/Macrocrystals)	17	3.8	3.8
Irinotecan Hydrochloride	13	3.8	3.8
Loratadine And Pseudoephedrine Sulfate	8	3.8	3.8
Hydromorphone Hydrochloride	91	3.7	3.7
Azacitidine	29	3.7	3.7
Liraglutide	48	3.6	3.6
Docusate Sodium	56	3.6	3.6
Norepinephrine Bitartrate	14	3.6	3.6
Atropine	8	3.6	3.6
Iohexol	8	3.6	3.6
Fluconazole	67	3.6	3.6
Insulin Glargine-Yfgn	21	3.6	3.6
Amphotericin B	12	3.6	3.6
Methylprednisolone	130	3.6	3.6
Duloxetine	66	3.6	3.6
Standardized Senna Concentrate	12	3.6	3.6
Granisetron	10	3.6	3.6
Telmisartan	17	3.6	3.6
Lubiprostone	9	3.6	3.6
Piperacillin And Tazobactam	12	3.5	3.5
Quinine	8	3.5	3.5
Trifluridine And Tipiracil	10	3.5	3.5
Loperamide Hydrochloride	41	3.4	3.4
Sucralfate	22	3.4	3.4
Potassium Chloride, Dextrose Monohydrate	84	3.4	3.4
Potassium Chloride Oral	84	3.4	3.4
Potassium Chloride Extended-Release	84	3.4	3.4
Etonogestrel And Ethinyl Estradiol	20	3.4	3.4
Esomeprazole Magnesium	206	3.4	3.4
Exenatide	47	3.4	3.4
Efavirenz	10	3.3	3.4
Lanreotide Acetate	7	3.3	3.3
Magnesium Hydroxide	12	3.3	3.3
Pantoprazole Sodium	130	3.3	3.3
Metformin Hcl	49	3.3	3.3
Azacitidine For	16	3.3	3.3
Docusate Sodium 100Mg	21	3.3	3.3
Diphenoxylate Hydrochloride And Atropine Sulfate	12	3.3	3.3
Fosaprepitant Dimeglumine	12	3.3	3.3
Fluorouracil Cream, 0.5%	66	3.3	3.3
Prednisolone	153	3.2	3.2
Prednisolone Oral	153	3.2	3.2
Prednisolone Oral Solution	153	3.2	3.2
Fluorouracil	66	3.2	3.2
Clopidogrel Bisulfate	87	3.2	3.2
Albuterol	101	3.2	3.2
Hydrocortisone Sodium Succinate	8	3.2	3.2
Rocuronium Bromide	10	3.2	3.2
Dabigatran Etexilate Mesylate	61	3.2	3.2
Cetirizine	65	3.1	3.2
Tapentadol Hydrochloride	28	3.1	3.1
Leucovorin Calcium	16	3.1	3.1
Oxycodone Hydrochloride And Acetaminophen	82	3.1	3.1
Calcium Gluconate	10	3.1	3.1
Dabigatran Etexilate	64	3.1	3.1
Loratadine Tablet	44	3.1	3.1
Metoclopramide	45	3.1	3.1
Abacavir Sulfate	8	3.1	3.1
Nebivolol	13	3.0	3.0
Potassium Chloride	92	3.0	3.0
Cetiirizine	34	3.0	3.0
Isoniazid	13	3.0	3.0
Aripiprazole Oral	33	3.0	3.0
Aripiprazole Orally Disintegrating	33	3.0	3.0
Digoxin	57	3.0	3.0
Glimepiride	31	3.0	3.0
Nifedipine	37	2.9	2.9
Lactulose	30	2.9	2.9
Loperamide Hydrochloride Oral	8	2.9	2.9
Atenolol	101	2.9	2.9
Atazanavir	11	2.9	2.9
Busulfan	12	2.8	2.8
Ketoprofen	10	2.8	2.8
Quinapril Hydrochloride	6	2.8	2.8
Fexofenadine Hcl	7	2.8	2.8
Deferasirox	20	2.8	2.8
Midazolam	19	2.8	2.8
Cytarabine	45	2.8	2.8
Bimekizumab	16	2.8	2.8
Bisoprolol Fumarate	101	2.8	2.8
Norepinephrine	8	2.8	2.8
Cefepime Hydrochloride	12	2.8	2.8
Levodopa	9	2.8	2.8
Anti-Thymocyte Globulin (Rabbit)	6	2.8	2.8
Sitagliptin And Metformin Hydrochloride	16	2.8	2.8
Oxaliplatin	54	2.7	2.7
Vancomycin Hydrochloride	48	2.7	2.7
Valacyclovir Hydrochloride	51	2.7	2.7
Cetirizine Hydrochloride	118	2.7	2.7
Isosorbide Mononitrate	15	2.7	2.7
Bicalutamide	11	2.7	2.7
Sennosides 8.6 Mg Tablets	15	2.7	2.7
Lamivudine	22	2.7	2.7
Senna	15	2.7	2.7
Metolazone	8	2.7	2.7
Midazolam Hydrochloride	19	2.6	2.6
Abiraterone Acetate	29	2.6	2.6
Aprepitant	13	2.6	2.6
Diltiazem Hydrochloride Extended-Release Tablets	8	2.6	2.6
Ribavirin	45	2.6	2.6
Levofloxacin	42	2.6	2.6
Levofloxacin In 5% Dextrose	42	2.6	2.6
Sitagliptin	50	2.6	2.6
Clopidogrel	136	2.6	2.6
Vancomycin	40	2.6	2.6
Senna Leaf	16	2.6	2.6
Rifampin	10	2.6	2.6
Amoxicillin	52	2.6	2.6
Loratadine	73	2.5	2.6
Metformin Hydrochloride	40	2.5	2.5
Omeprazole Magnesium	293	2.5	2.5
Remdesivir	9	2.5	2.5
Labetalol	9	2.5	2.5
Aspirin 325 Mg	333	2.5	2.5
Aspirin 81 Mg	333	2.5	2.5
Pioglitazone	29	2.5	2.5
Fentanyl Citrate	12	2.5	2.5
Warfarin Sodium	31	2.5	2.5
Metformin Hydrochloride Tablets	38	2.5	2.5
Metformin Hydrochloride Extended-Release Tablets	38	2.5	2.5
Metformin Hydrochloride Tablet	38	2.5	2.5
Apixaban	44	2.5	2.5
Linagliptin	12	2.5	2.5
Aspirin	338	2.4	2.4
Amlodipine Besylate And Benazepril Hydrochloride	6	2.4	2.4
Nivolumab	62	2.4	2.4
Oral Semaglutide	47	2.4	2.4
Durvalumab	13	2.4	2.4
Tamsulosin Hydrochloride	13	2.4	2.4
Duloxetine Hydrochloride	118	2.4	2.4
Mercaptopurine	11	2.4	2.4
Lamivudine Oral	16	2.4	2.4
Rituximab	132	2.4	2.4
Amlodipine Besylate And Valsartan	7	2.4	2.4
Ziprasidone Mesylate	9	2.4	2.4
Everolimus	32	2.4	2.4
Ezetimibe	47	2.3	2.3
Ivacaftor	5	2.3	2.3
Cefepime	9	2.3	2.3
Warfarin	79	2.3	2.3
Lovastatin	16	2.3	2.3
Loperamide Hcl	8	2.3	2.3
Bupropion Hydrochloride	61	2.3	2.3
Phenobarbital	9	2.3	2.3
Allopurinol	96	2.3	2.3
Tolvaptan	9	2.3	2.3
Tirzepatide	99	2.3	2.3
Orlistat	16	2.3	2.3
Fondaparinux Sodium	5	2.3	2.3
Temozolomide	13	2.3	2.3
Dornase Alfa	12	2.3	2.3
Doxazosin	17	2.3	2.3
Cabozantinib	29	2.3	2.3
Sumatriptan	23	2.3	2.3
Entecavir	7	2.2	2.2
Cyclophosphamide Injection, Solution	105	2.2	2.2
Cyclophosphamide	105	2.2	2.2
Cyclophosphamide For Injection	105	2.2	2.2
Zidovudine	8	2.2	2.2
Ondansetron	65	2.2	2.2
Ondansetron Tablets	65	2.2	2.2
Carvedilol	80	2.2	2.2
Atezolizumab	23	2.2	2.2
Loratadine Oral	29	2.2	2.2
Dexamethasone Sodium Phosphate	6	2.2	2.2
Prasugrel Hydrochloride	6	2.2	2.2
Tobramycin Solution	7	2.2	2.2
Dexamethasone 1.5 Mg	168	2.2	2.2
Propofol	21	2.1	2.1
Dexamethasone	168	2.1	2.1
Doxorubicin	51	2.1	2.1
Zoledronic Acid	23	2.1	2.1
Venetoclax	35	2.1	2.1
Ziprasidone	10	2.1	2.1
Tobramycin Sulfate	7	2.1	2.1
Axitinib	11	2.1	2.1
Human Insulin	7	2.1	2.1
Tramadol Hydrochloride	21	2.1	2.1
Bosutinib	5	2.1	2.1
Eculizumab	30	2.1	2.1
Obinutuzumab	9	2.0	2.0
Vincristine Sulfate	16	2.0	2.0
Letrozole Tablets	26	2.0	2.0
Dapagliflozin	17	2.0	2.0
Epoprostenol	7	2.0	2.0
Gemcitabine Hydrochloride	28	2.0	2.0
Doxorubicin Hydrochloride	17	1.9	1.9
Cladribine	5	1.9	1.9
Baricitinib	5	1.9	1.9
Paclitaxel	51	1.9	1.9
Ipilimumab	22	1.9	1.9
Nilotinib	15	1.9	1.9
Gemcitabine	20	1.9	1.9
Ticagrelor	16	1.9	1.9
Daratumumab	20	1.9	1.9
Hydrocodone Bitartrate And Acetaminophen	28	1.9	1.9
Carfilzomib	14	1.8	1.8
Capecitabine	45	1.8	1.8
Paclitaxel (Aibumin-Bound)	40	1.8	1.8
Bortezomib	43	1.8	1.8
Nintedanib	15	1.8	1.8
Insulin Human	19	1.8	1.8
Empagliflozin	32	1.8	1.8
Ado-Trastuzumab Emtansine	4	1.8	1.8
Eszopiclone	12	1.8	1.8
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	1.8	1.8
Icosapent Ethyl	4	1.8	1.8
Pancrelipase	18	1.7	1.7
Suvorexant	6	1.7	1.7
Cisplatin	36	1.7	1.7
Riociguat	15	1.7	1.7
Etoposide	33	1.7	1.7
Rasagiline Mesylate	5	1.7	1.7
Bosentan	22	1.6	1.6
Canagliflozin	13	1.6	1.6
Carboplatin	55	1.6	1.6
Sorafenib	9	1.6	1.6
Regorafenib	5	1.6	1.6
Dulaglutide	38	1.6	1.6
Dabrafenib	9	1.6	1.6
Insulin Degludec	10	1.6	1.6
Pemetrexed Disodium	16	1.6	1.6
Guselkumab	15	1.6	1.6
Macitentan	29	1.6	1.6
Erlotinib	4	1.5	1.5
Sofosbuvir	8	1.5	1.5
Axicabtagene Ciloleucel	4	1.5	1.5
Erlotinib Hydrochloride	5	1.5	1.5
Brentuximab Vedotin	4	1.5	1.5
Velpatasvir And Sofosbuvir	5	1.5	1.5
Aflibercept	12	1.4	1.4
Dofetilide	4	1.4	1.4
Acetaminophen, Aspirin, And Caffeine	8	1.4	1.4
Oseltamivir	3	1.4	1.4
Tobramycin	9	1.4	1.4
Trametinib	9	1.4	1.4
Darbepoetin Alfa	20	1.4	1.4
Peginterferon Alfa-2A	20	1.4	1.4
Hydrocodone Bitartrate	16	1.4	1.4
Naproxen Sodium Tablet	19	1.3	1.3
Enzalutamide	21	1.3	1.3
Insulin Lispro	48	1.3	1.3
Eltrombopag Olamine	8	1.3	1.3
Travoprost	3	1.3	1.3
Ustekinumab	35	1.3	1.3
Vismodegib	3	1.3	1.3
Pazopanib Hydrochloride	9	1.2	1.2
Gefitinib	3	1.2	1.2
Ixazomib	9	1.2	1.2
Polatuzumab Vedotin	3	1.1	1.1
Medroxyprogesterone Acetate	15	1.1	1.1
Lenalidomide	116	1.0	1.0
Methoxy Polyethylene Glycol-Epoetin Beta	3	1.0	1.0
Ledipasvir And Sofosbuvir	5	1.0	1.0
Conjugated Estrogens And Medroxyprogesterone Acetate	6	0.9	0.9
Ixekizumab	9	0.9	0.9
Crizotinib	3	0.9	0.9
Sarilumab	6	0.8	0.8
Pomalidomide	18	0.7	0.7
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	4	0.5	0.5
Evolocumab	20	0.5	0.5
Cinacalcet Hydrochloride	5	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.