OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Efinaconazole

136 flagged reaction(s) · 6,749 total co-reports · max PRR 152.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Aspiration 150 152.3 165.0 signal
2 Sputum Discoloured 121 140.7 150.0 signal
3 Obstructive Airways Disorder 121 118.9 126.7 signal
4 Blood Test Abnormal 140 109.3 117.7 signal
5 Pulmonary Fibrosis 125 71.4 76.3 signal
6 Pulmonary Mass 94 69.0 72.5 signal
7 Transaminases Increased 139 68.3 73.5 signal
8 Liver Function Test Increased 120 61.4 65.4 signal
9 Haemoptysis 122 47.5 50.7 signal
10 Full Blood Count Abnormal 40 41.3 42.2 signal
11 Hypercholesterolaemia 36 41.0 41.7 signal
12 Hyperlipidaemia 44 40.0 40.9 signal
13 Hypoxia 120 37.2 39.6 signal
14 Lower Respiratory Tract Infection 152 36.5 39.5 signal
15 Upper Respiratory Tract Infection 152 35.8 38.8 signal
16 Micturition Urgency 37 35.5 36.2 signal
17 Incorrect Route Of Product Administration 52 33.7 34.6 signal
18 Bacterial Infection 53 31.0 31.9 signal
19 Ulcer 45 30.7 31.4 signal
20 Application Site Pain 60 29.6 30.6 signal
21 Gout 44 26.6 27.2 signal
22 End Stage Renal Disease 44 26.0 26.6 signal
23 Appendicitis 22 25.7 26.0 signal
24 Blood Creatinine Increased 148 24.6 26.6 signal
25 Neuralgia 52 23.3 23.9 signal
26 Ventricular Fibrillation 23 22.4 22.7 signal
27 Pleural Effusion 122 21.8 23.2 signal
28 Joint Injury 41 20.8 21.3 signal
29 Wheezing 113 20.8 22.0 signal
30 Application Site Erythema 50 20.6 21.2 signal
31 Multiple Organ Dysfunction Syndrome 49 19.1 19.5 signal
32 Musculoskeletal Stiffness 152 18.8 20.4 signal
33 Gastrooesophageal Reflux Disease 133 18.0 19.3 signal
34 Product Packaging Quantity Issue 18 17.9 18.1 signal
35 Intervertebral Disc Degeneration 15 17.5 17.6 signal
36 Blister 89 17.3 18.0 signal
37 Cardiogenic Shock 22 16.7 16.9 signal
38 Oedema Peripheral 170 15.1 16.5 signal
39 Asthma 154 14.9 16.1 signal
40 Coronary Artery Disease 40 14.2 14.5 signal
41 Cardiovascular Disorder 33 14.0 14.2 signal
42 Brain Fog 18 13.4 13.5 signal
43 Blood Pressure Fluctuation 28 12.6 12.8 signal
44 Application Site Irritation 14 12.2 12.3 signal
45 Immunodeficiency 16 11.8 11.9 signal
46 Rotator Cuff Syndrome 14 11.8 11.9 signal
47 Transient Ischaemic Attack 36 11.5 11.7 signal
48 Drug Effect Incomplete 39 11.5 11.7 signal
49 Insurance Issue 15 11.0 11.0 signal
50 Blood Pressure Systolic Increased 19 10.5 10.6 signal
51 Chronic Obstructive Pulmonary Disease 50 10.4 10.7 signal
52 Application Site Rash 13 10.2 10.3 signal
53 General Physical Health Deterioration 108 10.2 10.8 signal
54 Drug Administered At Inappropriate Site 10 10.1 10.2 signal
55 Tremor 154 10.1 10.8 signal
56 Application Site Pruritus 21 10.0 10.1 signal
57 Inability To Afford Medication 9 9.9 10.0 signal
58 Apathy 13 9.7 9.8 signal
59 Drug Hypersensitivity 173 9.7 10.5 signal
60 Sciatica 14 9.6 9.6 signal
61 Swelling 82 9.5 9.9 signal
62 Hyponatraemia 49 9.5 9.7 signal
63 Anaemia 162 9.2 10.0 signal
64 Eructation 16 9.1 9.2 signal
65 Liver Disorder 37 9.1 9.2 signal
66 Stress 59 8.9 9.2 signal
67 Bone Disorder 15 8.9 8.9 signal
68 Dermatitis Contact 9 8.6 8.6 signal
69 Ascites 23 8.5 8.6 signal
70 Body Temperature Increased 15 8.0 8.0 signal
71 Mouth Ulceration 15 7.7 7.8 signal
72 Feeding Disorder 14 7.6 7.7 signal
73 Sleep Disorder 48 7.4 7.6 signal
74 Diabetes Mellitus 51 7.2 7.4 signal
75 Abdominal Pain Upper 136 7.2 7.7 signal
76 Constipation 142 7.1 7.6 signal
77 Secretion Discharge 8 7.0 7.1 signal
78 Lung Disorder 31 6.9 7.0 signal
79 Fungal Infection 21 6.8 6.9 signal
80 Hypersomnia 18 6.8 6.9 signal
81 Thrombosis 48 6.5 6.6 signal
82 Frequent Bowel Movements 16 6.5 6.5 signal
83 Tenderness 6 6.2 6.3 signal
84 Cough 158 6.1 6.6 signal
85 Intentional Product Misuse 48 6.0 6.1 signal
86 Product Dose Omission Issue 157 6.0 6.4 signal
87 Product Administered At Inappropriate Site 10 6.0 6.0 signal
88 Product Prescribing Error 13 6.0 6.0 signal
89 Asthenia 201 5.8 6.4 signal
90 Dermatitis 11 5.8 5.8 signal
91 Skin Fissures 10 5.7 5.8 signal
92 Disease Recurrence 25 5.7 5.7 signal
93 Pulmonary Embolism 50 5.7 5.8 signal
94 Femur Fracture 16 5.6 5.6 signal
95 Product Use Issue 94 5.5 5.7 signal
96 Skin Exfoliation 41 5.4 5.4 signal
97 Muscle Atrophy 6 5.2 5.2 signal
98 Erythema 95 5.0 5.2 signal
99 Burning Sensation 32 5.0 5.0 signal
100 Economic Problem 7 4.9 4.9 signal
101 Skin Disorder 15 4.9 4.9 signal
102 Mass 6 4.6 4.7 signal
103 Accidental Exposure To Product 42 4.6 4.6 signal
104 Mood Swings 13 4.4 4.4 signal
105 Lactic Acidosis 13 4.4 4.4 signal
106 Rash Macular 14 4.4 4.4 signal
107 Eye Irritation 22 4.3 4.3 signal
108 Drug Level Decreased 4 4.2 4.3 signal
109 Incorrect Drug Administration Duration 11 4.2 4.2 signal
110 Drug Administration Error 12 4.2 4.2 signal
111 Red Blood Cell Sedimentation Rate Increased 4 3.9 3.9 signal
112 Product Quality Issue 48 3.9 3.9 signal
113 No Adverse Event 62 3.8 3.9 signal
114 Skin Irritation 16 3.8 3.8 signal
115 Medication Error 19 3.7 3.7 signal
116 Arthropathy 19 3.7 3.7 signal
117 Anhedonia 9 3.7 3.7 signal
118 Local Swelling 6 3.7 3.7 signal
119 Device Leakage 14 3.6 3.6 signal
120 Extra Dose Administered 13 3.5 3.6 signal
121 Inflammatory Bowel Disease 3 3.3 3.3 no signal
122 Incorrect Product Administration Duration 6 3.2 3.2 signal
123 Device Delivery System Issue 7 2.9 2.9 signal
124 Therapy Interrupted 17 2.7 2.7 signal
125 Expired Product Administered 8 2.6 2.6 signal
126 Drug Dose Omission 40 2.6 2.6 signal
127 Product Availability Issue 5 2.4 2.4 no signal
128 Exposure Via Skin Contact 5 2.4 2.4 no signal
129 Device Issue 18 2.2 2.2 signal
130 Product Physical Issue 4 2.2 2.2 no signal
131 Drug Dispensing Error 3 2.1 2.1 no signal
132 Wrong Technique In Product Usage Process 33 1.8 1.8 no signal
133 Incorrect Route Of Drug Administration 5 1.5 1.5 no signal
134 Skin Burning Sensation 9 1.4 1.4 no signal
135 Dermatitis Atopic 5 1.1 1.1 no signal
136 Device Breakage 3 0.8 0.8 no signal