OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Evolocumab

1,176 flagged reaction(s) · 368,094 total co-reports · max PRR 291.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Fractional Exhaled Nitric Oxide Increased 119 291.4 291.6 signal
2 Incorrect Disposal Of Product 1,683 144.8 146.3 signal
3 Low Density Lipoprotein Decreased 726 137.2 137.8 signal
4 Device Difficult To Use 32,925 129.9 162.9 signal
5 Intercepted Product Administration Error 2,520 62.9 63.9 signal
6 Low Density Lipoprotein Abnormal 198 61.7 61.7 signal
7 Drug Dose Omission By Device 24,638 61.6 72.5 signal
8 Product Communication Issue 2,723 61.0 62.0 signal
9 Type Iia Hyperlipidaemia 69 56.7 56.7 signal
10 Blood Cholesterol Decreased 455 41.9 42.0 signal
11 Computerised Tomogram Heart Abnormal 18 40.2 40.2 signal
12 Lipoprotein (a) Increased 69 39.2 39.2 signal
13 Lack Of Administration Site Rotation 52 27.3 27.3 signal
14 Product Knowledge Deficit 96 26.6 26.6 signal
15 Accidental Exposure To Product 16,804 26.2 29.1 signal
16 Low Density Lipoprotein Increased 1,170 23.2 23.3 signal
17 Occupational Exposure To Product 956 22.4 22.6 signal
18 Injection Site Indentation 300 22.3 22.4 signal
19 Product Preparation Error 2,840 20.6 20.9 signal
20 Device Use Error 4,250 18.4 18.9 signal
21 Incorrect Dose Administered By Device 3,021 17.5 17.8 signal
22 Lack Of Injection Site Rotation 194 16.4 16.4 signal
23 Wrong Technique In Product Usage Process 22,365 16.1 18.5 signal
24 Incorrect Dose Administered By Product 166 15.8 15.9 signal
25 Vascular Stent Stenosis 44 15.3 15.3 signal
26 Rubber Sensitivity 156 14.7 14.7 signal
27 High Density Lipoprotein Abnormal 23 14.0 14.0 signal
28 Device Dispensing Error 115 13.9 13.9 signal
29 Application Site Mass 27 13.9 13.9 signal
30 Obstructive Sleep Apnoea Syndrome 129 13.2 13.2 signal
31 Fear Of Injection 626 12.7 12.8 signal
32 Circumstance Or Information Capable Of Leading To Medication Error 2,878 12.1 12.3 signal
33 Myoglobin Blood Increased 123 11.3 11.3 signal
34 Product Storage Error 6,676 10.8 11.2 signal
35 Injury Associated With Device 1,469 10.2 10.3 signal
36 High Density Lipoprotein Increased 66 9.3 9.3 signal
37 Blood Triglycerides Decreased 22 9.0 9.0 signal
38 Percutaneous Coronary Intervention 18 8.7 8.7 signal
39 Injection Site Bruising 4,800 8.4 8.6 signal
40 Rhinorrhoea 3,634 7.7 7.9 signal
41 Vascular Stent Occlusion 22 7.4 7.4 signal
42 Blood Triglycerides Abnormal 47 7.3 7.3 signal
43 Injection Site Haemorrhage 4,029 6.9 7.1 signal
44 Injection Site Discomfort 518 6.8 6.8 signal
45 Lipids Abnormal 34 6.4 6.4 signal
46 Blood Cholesterol Abnormal 213 6.2 6.2 signal
47 Plantar Fasciitis 147 5.9 5.9 signal
48 Stent Placement 350 5.9 5.9 signal
49 Injection Site Discolouration 528 5.7 5.8 signal
50 Injection Site Hypoaesthesia 60 5.7 5.7 signal
51 Brain Natriuretic Peptide Increased 125 5.5 5.5 signal
52 Influenza Like Illness 3,179 5.2 5.2 signal
53 Injection Site Paraesthesia 58 5.2 5.2 signal
54 High Density Lipoprotein Decreased 127 5.1 5.1 signal
55 Injection Site Vesicles 221 4.9 4.9 signal
56 Injection Site Mass 1,347 4.9 4.9 signal
57 Injection Site Pain 10,927 4.8 5.1 signal
58 Injection Site Laceration 23 4.8 4.8 signal
59 Lipids Increased 71 4.7 4.7 signal
60 Vascular Graft 98 4.5 4.5 signal
61 Cardiac Operation 288 4.5 4.5 signal
62 Blood Triglycerides Increased 600 4.5 4.5 signal
63 Coronary Artery Bypass 190 4.4 4.4 signal
64 Product Administration Error 656 4.4 4.4 signal
65 Paranasal Sinus Hypersecretion 124 4.3 4.3 signal
66 Myalgia 5,419 4.3 4.4 signal
67 Subclavian Vein Thrombosis 35 4.1 4.1 signal
68 Injection Site Macule 21 4.0 4.0 signal
69 Drug Dose Omission 4,929 3.9 4.0 signal
70 Muscle Disorder 233 3.8 3.8 signal
71 Adverse Reaction 379 3.8 3.8 signal
72 Carotid Arteriosclerosis 29 3.8 3.8 signal
73 Aortic Valve Replacement 35 3.8 3.8 signal
74 Coronary Arterial Stent Insertion 143 3.8 3.8 signal
75 Intercepted Product Storage Error 95 3.7 3.7 signal
76 Injection Site Swelling 2,058 3.6 3.6 signal
77 Blood Cholesterol Increased 1,255 3.6 3.6 signal
78 Catheterisation Cardiac 119 3.6 3.6 signal
79 Injection Site Scab 25 3.5 3.5 signal
80 Heart Valve Replacement 38 3.4 3.4 signal
81 Muscle Discomfort 20 3.4 3.4 signal
82 Injection Site Injury 141 3.4 3.4 signal
83 Upper-airway Cough Syndrome 199 3.2 3.2 signal
84 Back Pain 5,587 3.2 3.3 signal
85 Device Defective 372 3.0 3.0 signal
86 Vascular Occlusion 47 2.9 2.9 signal
87 Injection Site Urticaria 527 2.9 2.9 signal
88 Medical Device Implantation 31 2.7 2.7 signal
89 Product Administered At Inappropriate Site 366 2.7 2.7 signal
90 Glycosylated Haemoglobin Decreased 32 2.6 2.6 signal
91 Sinus Disorder 392 2.6 2.6 signal
92 Device Issue 1,699 2.6 2.6 signal
93 Underdose 1,421 2.6 2.6 signal
94 Ear Congestion 52 2.5 2.5 signal
95 Exposure Via Skin Contact 434 2.5 2.5 signal
96 Injection Site Hypersensitivity 59 2.5 2.5 signal
97 Injection Site Induration 246 2.5 2.5 signal
98 Peripheral Artery Occlusion 26 2.4 2.4 signal
99 Hypoacusis 780 2.4 2.4 signal
100 Muscle Spasms 3,274 2.3 2.4 signal
101 Glycosylated Haemoglobin Increased 449 2.3 2.3 signal
102 Sensation Of Foreign Body 148 2.3 2.3 signal
103 Injection Site Rash 530 2.3 2.3 signal
104 Secretion Discharge 215 2.3 2.3 signal
105 Colonoscopy 36 2.1 2.1 signal
106 Application Site Haemorrhage 45 2.1 2.1 signal
107 Injection Related Reaction 26 2.1 2.1 signal
108 Oropharyngeal Pain 1,496 2.1 2.1 signal
109 Muscle Fatigue 67 2.1 2.1 signal
110 Carotid Artery Occlusion 58 2.1 2.1 signal
111 Wrong Technique In Device Usage Process 724 2.1 2.1 signal
112 Injection Site Erythema 1,930 2.1 2.1 signal
113 Coronary Artery Occlusion 215 2.0 2.0 signal
114 Musculoskeletal Disorder 294 2.0 2.0 signal
115 Injection Site Extravasation 190 2.0 2.0 no signal
116 Arterial Disorder 29 2.0 2.0 no signal
117 Injection Site Pruritus 999 2.0 2.0 no signal
118 Product Temperature Excursion Issue 70 1.9 1.9 no signal
119 Nasal Pruritus 18 1.9 1.9 no signal
120 Increased Upper Airway Secretion 75 1.9 1.9 no signal
121 Sleep Disorder Due To A General Medical Condition 234 1.9 1.9 no signal
122 Implantable Defibrillator Insertion 19 1.9 1.9 no signal
123 Musculoskeletal Pain 761 1.9 1.9 no signal
124 Respiratory Tract Congestion 229 1.9 1.9 no signal
125 Sneezing 321 1.9 1.9 no signal
126 Injection Site Scar 40 1.9 1.9 no signal
127 Carotid Artery Disease 18 1.8 1.8 no signal
128 Nasopharyngitis 2,599 1.8 1.9 no signal
129 Exostosis 126 1.8 1.8 no signal
130 Therapy Non-responder 612 1.8 1.8 no signal
131 Respiratory Symptom 38 1.8 1.8 no signal
132 Increased Tendency To Bruise 124 1.8 1.8 no signal
133 Sinus Pain 31 1.8 1.8 no signal
134 Angina Unstable 87 1.7 1.7 no signal
135 Spinal Operation 160 1.7 1.7 no signal
136 Sleep Disorder Due To General Medical Condition, Insomnia Type 84 1.7 1.7 no signal
137 Unevaluable Event 981 1.7 1.7 no signal
138 Arterial Occlusive Disease 101 1.7 1.7 no signal
139 Nasal Disorder 34 1.7 1.7 no signal
140 Injection Site Inflammation 63 1.7 1.7 no signal
141 Middle Ear Effusion 28 1.7 1.7 no signal
142 Arteriosclerosis 120 1.7 1.7 no signal
143 Glucose Tolerance Impaired 74 1.6 1.6 no signal
144 Eye Operation 57 1.6 1.6 no signal
145 Intermittent Claudication 20 1.6 1.6 no signal
146 Injection Site Irritation 158 1.6 1.6 no signal
147 Shoulder Arthroplasty 33 1.6 1.6 no signal
148 Therapy Interrupted 842 1.6 1.6 no signal
149 Device Failure 184 1.6 1.6 no signal
150 Angioplasty 18 1.6 1.6 no signal
151 Coronary Artery Stenosis 60 1.6 1.6 no signal
152 Throat Clearing 44 1.5 1.5 no signal
153 Pain In Extremity 3,485 1.5 1.6 no signal
154 Nasal Congestion 686 1.5 1.5 no signal
155 Sinus Congestion 158 1.5 1.5 no signal
156 Back Disorder 189 1.5 1.5 no signal
157 Polymyalgia Rheumatica 36 1.5 1.5 no signal
158 Blood Calcium Abnormal 19 1.5 1.5 no signal
159 Obstructive Airways Disorder 128 1.5 1.5 no signal
160 Musculoskeletal Discomfort 197 1.5 1.5 no signal
161 Blood Creatine Phosphokinase Increased 334 1.5 1.5 no signal
162 Carotid Artery Stenosis 40 1.5 1.5 no signal
163 Muscle Tightness 184 1.5 1.5 no signal
164 Incorrect Drug Administration Rate 48 1.5 1.5 no signal
165 Cardiac Ablation 20 1.5 1.5 no signal
166 Joint Lock 32 1.5 1.5 no signal
167 Dry Throat 114 1.5 1.5 no signal
168 Cardiac Pacemaker Insertion 67 1.5 1.5 no signal
169 Product Dispensing Issue 40 1.5 1.5 no signal
170 Groin Pain 97 1.4 1.4 no signal
171 Dysphonia 639 1.4 1.4 no signal
172 Product Supply Issue 77 1.4 1.4 no signal
173 Aortic Stenosis 38 1.4 1.4 no signal
174 Rehabilitation Therapy 42 1.4 1.4 no signal
175 Body Temperature Abnormal 20 1.4 1.4 no signal
176 Essential Hypertension 28 1.4 1.4 no signal
177 Mobility Decreased 774 1.4 1.4 no signal
178 Laryngitis 117 1.4 1.4 no signal
179 Stenosis 20 1.4 1.4 no signal
180 Catheter Placement 20 1.4 1.4 no signal
181 Viral Upper Respiratory Tract Infection 51 1.4 1.4 no signal
182 Influenza 1,186 1.4 1.4 no signal
183 Therapeutic Response Unexpected 477 1.4 1.4 no signal
184 Rhinitis 85 1.4 1.4 no signal
185 Rash Pruritic 566 1.4 1.4 no signal
186 Drug Effect Incomplete 384 1.4 1.4 no signal
187 Brain Fog 152 1.4 1.4 no signal
188 Intentional Product Misuse 902 1.4 1.4 no signal
189 Papule 72 1.4 1.4 no signal
190 Trigger Finger 42 1.3 1.3 no signal
191 Product Dispensing Error 225 1.3 1.3 no signal
192 Pruritus Generalised 225 1.3 1.3 no signal
193 Shoulder Operation 43 1.3 1.3 no signal
194 Product Dose Omission 671 1.3 1.3 no signal
195 Paranasal Sinus Discomfort 38 1.3 1.3 no signal
196 Neck Pain 564 1.3 1.3 no signal
197 Muscular Weakness 1,145 1.3 1.3 no signal
198 Aortic Valve Stenosis 18 1.3 1.3 no signal
199 Application Site Swelling 50 1.3 1.3 no signal
200 Application Site Discomfort 18 1.3 1.3 no signal
201 Laboratory Test Abnormal 294 1.3 1.3 no signal
202 Angina Pectoris 287 1.3 1.3 no signal
203 Limb Discomfort 305 1.3 1.3 no signal
204 Venous Occlusion 18 1.3 1.3 no signal
205 Adverse Event 905 1.3 1.3 no signal
206 Arthralgia 4,061 1.3 1.3 no signal
207 Injection Site Warmth 201 1.3 1.3 no signal
208 Product Administration Interrupted 73 1.2 1.2 no signal
209 Peripheral Arterial Occlusive Disease 39 1.2 1.2 no signal
210 Pharyngeal Swelling 90 1.2 1.2 no signal
211 Vascular Stent Thrombosis 19 1.2 1.2 no signal
212 Injection Site Reaction 641 1.2 1.2 no signal
213 Aphonia 130 1.2 1.2 no signal
214 Joint Noise 18 1.2 1.2 no signal
215 Blood Glucose Increased 1,755 1.2 1.2 no signal
216 Limb Operation 44 1.2 1.2 no signal
217 Neck Surgery 21 1.2 1.2 no signal
218 Oropharyngeal Discomfort 81 1.2 1.2 no signal
219 Ear Swelling 19 1.2 1.2 no signal
220 Head Discomfort 158 1.2 1.2 no signal
221 Sluggishness 91 1.2 1.2 no signal
222 Cataract Operation 53 1.2 1.2 no signal
223 Hernia Repair 23 1.2 1.2 no signal
224 Foreign Body In Throat 27 1.2 1.2 no signal
225 Upper Respiratory Tract Infection 404 1.1 1.1 no signal
226 Knee Operation 85 1.1 1.1 no signal
227 Diabetes Mellitus 669 1.1 1.1 no signal
228 Rash Vesicular 42 1.1 1.1 no signal
229 Coronary Artery Disease 265 1.1 1.1 no signal
230 Memory Impairment 1,187 1.1 1.1 no signal
231 Arteriosclerosis Coronary Artery 57 1.1 1.1 no signal
232 Sciatica 136 1.1 1.1 no signal
233 Seasonal Allergy 120 1.1 1.1 no signal
234 Arthritis 669 1.1 1.1 no signal
235 Skin Odour Abnormal 33 1.1 1.1 no signal
236 Sinus Headache 50 1.1 1.1 no signal
237 Pharyngeal Disorder 24 1.1 1.1 no signal
238 Arthropod Bite 61 1.1 1.1 no signal
239 Drug Effect Less Than Expected 117 1.1 1.1 no signal
240 Incorrect Route Of Product Administration 139 1.1 1.1 no signal
241 Device Malfunction 555 1.1 1.1 no signal
242 Ear Disorder 38 1.1 1.1 no signal
243 Embolism Venous 25 1.1 1.1 no signal
244 Limb Mass 18 1.1 1.1 no signal
245 Cough 2,286 1.1 1.1 no signal
246 Ill-defined Disorder 493 1.1 1.1 no signal
247 Blood Glucose Abnormal 150 1.1 1.1 no signal
248 Spinal Stenosis 33 1.1 1.1 no signal
249 Disability 156 1.0 1.0 no signal
250 Ear Pain 153 1.0 1.0 no signal
251 Tongue Discomfort 33 1.0 1.0 no signal
252 Blood Pressure Abnormal 155 1.0 1.0 no signal
253 Knee Arthroplasty 163 1.0 1.0 no signal
254 Inappropriate Schedule Of Drug Administration 561 1.0 1.0 no signal
255 Bone Pain 454 1.0 1.0 no signal
256 Migraine With Aura 21 1.0 1.0 no signal
257 Cardiac Flutter 50 1.0 1.0 no signal
258 Inappropriate Schedule Of Product Administration 1,358 1.0 1.0 no signal
259 Muscle Strain 66 1.0 1.0 no signal
260 Bladder Pain 24 1.0 1.0 no signal
261 Contusion 729 1.0 1.0 no signal
262 Upper Respiratory Tract Congestion 22 1.0 1.0 no signal
263 Gallbladder Operation 30 1.0 1.0 no signal
264 Hepatic Pain 32 1.0 1.0 no signal
265 Muscle Rupture 29 1.0 1.0 no signal
266 Dementia 208 1.0 1.0 no signal
267 Pulse Abnormal 18 1.0 1.0 no signal
268 Device Physical Property Issue 55 1.0 1.0 no signal
269 Injection Site Haematoma 107 0.9 0.9 no signal
270 Macular Degeneration 87 0.9 0.9 no signal
271 Throat Irritation 324 0.9 0.9 no signal
272 Surgery 417 0.9 0.9 no signal
273 Musculoskeletal Chest Pain 111 0.9 0.9 no signal
274 Pancreatic Disorder 35 0.9 0.9 no signal
275 Urine Odour Abnormal 42 0.9 0.9 no signal
276 Feeling Abnormal 1,711 0.9 0.9 no signal
277 Eosinophilia 124 0.9 0.9 no signal
278 Gait Inability 234 0.9 0.9 no signal
279 Intercepted Medication Error 33 0.9 0.9 no signal
280 Hip Arthroplasty 107 0.9 0.9 no signal
281 Multiple Use Of Single-use Product 39 0.9 0.9 no signal
282 Pneumothorax 111 0.9 0.9 no signal
283 Spinal Fusion Surgery 28 0.9 0.9 no signal
284 Gastrointestinal Pain 76 0.9 0.9 no signal
285 Joint Stiffness 182 0.9 0.9 no signal
286 Myopathy 60 0.9 0.9 no signal
287 Autoimmune Disorder 66 0.9 0.9 no signal
288 Exfoliative Rash 18 0.9 0.9 no signal
289 Injection Site Papule 31 0.9 0.9 no signal
290 Therapy Cessation 350 0.9 0.9 no signal
291 Ventricular Hypokinesia 22 0.9 0.9 no signal
292 Adverse Drug Reaction 611 0.9 0.9 no signal
293 Dyspnoea Exertional 256 0.9 0.9 no signal
294 Paraesthesia Oral 98 0.9 0.9 no signal
295 Myocardial Infarction 1,196 0.9 0.9 no signal
296 Gout 122 0.9 0.9 no signal
297 Muscle Atrophy 85 0.9 0.9 no signal
298 Peripheral Vascular Disorder 35 0.9 0.9 no signal
299 Varicose Vein 35 0.9 0.9 no signal
300 Ear Discomfort 69 0.9 0.9 no signal
301 Blood Blister 21 0.9 0.9 no signal
302 Weight Bearing Difficulty 18 0.9 0.9 no signal
303 Sinusitis 682 0.9 0.9 no signal
304 Cardiac Disorder 622 0.9 0.9 no signal
305 Pulmonary Pain 19 0.9 0.9 no signal
306 Spondylitis 24 0.9 0.9 no signal
307 Rash Generalised 173 0.9 0.9 no signal
308 Aortic Arteriosclerosis 17 0.9 0.9 no signal
309 Nerve Compression 60 0.8 0.8 no signal
310 Chest Discomfort 663 0.8 0.8 no signal
311 Meniscus Injury 40 0.8 0.8 no signal
312 Macule 18 0.8 0.8 no signal
313 Chemotherapy 24 0.8 0.8 no signal
314 Haemorrhagic Diathesis 23 0.8 0.8 no signal
315 Product Label Confusion 37 0.8 0.8 no signal
316 Musculoskeletal Stiffness 556 0.8 0.8 no signal
317 Tendon Pain 48 0.8 0.8 no signal
318 Heart Rate Abnormal 35 0.8 0.8 no signal
319 Bowel Movement Irregularity 48 0.8 0.8 no signal
320 Needle Issue 180 0.8 0.8 no signal
321 Throat Tightness 170 0.8 0.8 no signal
322 Lacrimation Increased 188 0.8 0.8 no signal
323 Heart Valve Incompetence 18 0.8 0.8 no signal
324 Oral Mucosal Blistering 40 0.8 0.8 no signal
325 Myositis 56 0.8 0.8 no signal
326 Rash Papular 140 0.8 0.8 no signal
327 Eye Disorder 204 0.8 0.8 no signal
328 Lip Swelling 206 0.8 0.8 no signal
329 Pulmonary Congestion 81 0.8 0.8 no signal
330 Frustration Tolerance Decreased 49 0.8 0.8 no signal
331 Nervousness 319 0.8 0.8 no signal
332 Nasal Dryness 38 0.8 0.8 no signal
333 Transient Ischaemic Attack 204 0.8 0.8 no signal
334 Gait Disturbance 1,153 0.8 0.8 no signal
335 Liver Function Test Increased 128 0.8 0.8 no signal
336 Swelling Face 390 0.8 0.8 no signal
337 Overweight 32 0.8 0.8 no signal
338 Productive Cough 282 0.8 0.8 no signal
339 Peripheral Swelling 914 0.8 0.8 no signal
340 Vein Disorder 30 0.8 0.8 no signal
341 Prostatitis 18 0.8 0.8 no signal
342 Bronchitis 439 0.8 0.8 no signal
343 Renal Pain 62 0.8 0.8 no signal
344 Swollen Tongue 183 0.8 0.8 no signal
345 Amnesia 382 0.8 0.8 no signal
346 Hip Surgery 31 0.8 0.8 no signal
347 Skin Haemorrhage 84 0.8 0.8 no signal
348 Dizziness Postural 55 0.7 0.7 no signal
349 Blood Pressure Increased 874 0.7 0.7 no signal
350 Hypersensitivity 1,056 0.7 0.7 no signal
351 Fibromyalgia 138 0.7 0.7 no signal
352 Angiopathy 32 0.7 0.7 no signal
353 Product Preparation Issue 33 0.7 0.7 no signal
354 Urticaria 942 0.7 0.7 no signal
355 Acute Coronary Syndrome 47 0.7 0.7 no signal
356 Dysstasia 165 0.7 0.7 no signal
357 Chest Pain 1,044 0.7 0.7 no signal
358 Hepatic Enzyme Abnormal 28 0.7 0.7 no signal
359 Respiratory Disorder 168 0.7 0.7 no signal
360 Aneurysm 28 0.7 0.7 no signal
361 Concussion 43 0.7 0.7 no signal
362 Thyroid Mass 21 0.7 0.7 no signal
363 Tendonitis 86 0.7 0.7 no signal
364 Diverticulitis 152 0.7 0.7 no signal
365 Abnormal Faeces 45 0.7 0.7 no signal
366 Aortic Aneurysm 42 0.7 0.7 no signal
367 Renal Function Test Abnormal 25 0.7 0.7 no signal
368 Cerebrovascular Accident 918 0.7 0.7 no signal
369 Arthropathy 301 0.7 0.7 no signal
370 Pharyngeal Oedema 84 0.7 0.7 no signal
371 Burning Sensation 377 0.7 0.7 no signal
372 Injection Site Nodule 59 0.7 0.7 no signal
373 Tendon Injury 20 0.7 0.7 no signal
374 Blood Calcium Increased 47 0.7 0.7 no signal
375 Visual Impairment 657 0.7 0.7 no signal
376 Mass 74 0.7 0.7 no signal
377 Blood Test Abnormal 74 0.7 0.7 no signal
378 Skin Mass 35 0.7 0.7 no signal
379 Respiration Abnormal 36 0.7 0.7 no signal
380 Facial Pain 47 0.7 0.7 no signal
381 Renal Transplant 19 0.7 0.7 no signal
382 Weight Loss Poor 24 0.7 0.7 no signal
383 Exercise Tolerance Decreased 30 0.7 0.7 no signal
384 Onychoclasis 36 0.7 0.7 no signal
385 Illness 526 0.7 0.7 no signal
386 Fatigue 4,059 0.7 0.7 no signal
387 Toothache 94 0.7 0.7 no signal
388 Rash Erythematous 243 0.7 0.7 no signal
389 Tenderness 54 0.7 0.7 no signal
390 Lethargy 297 0.7 0.7 no signal
391 Hepatic Steatosis 96 0.7 0.7 no signal
392 Neuralgia 125 0.7 0.7 no signal
393 Tinnitus 237 0.7 0.7 no signal
394 Urine Abnormality 23 0.7 0.7 no signal
395 Intervertebral Disc Disorder 22 0.7 0.7 no signal
396 Hypoaesthesia Oral 77 0.7 0.7 no signal
397 Periorbital Swelling 28 0.7 0.7 no signal
398 Blood Glucose Fluctuation 56 0.7 0.7 no signal
399 Presyncope 123 0.7 0.7 no signal
400 Pain 3,120 0.7 0.7 no signal
401 Blood Testosterone Decreased 35 0.7 0.7 no signal
402 Chapped Lips 22 0.7 0.7 no signal
403 Scratch 52 0.7 0.7 no signal
404 Nasal Discomfort 40 0.7 0.7 no signal
405 Cerebral Disorder 37 0.7 0.7 no signal
406 Product Dose Omission Issue 1,426 0.6 0.6 no signal
407 Dizziness 2,490 0.6 0.6 no signal
408 Guillain-barre Syndrome 24 0.6 0.6 no signal
409 Gastric Infection 19 0.6 0.6 no signal
410 Drug Delivery System Malfunction 25 0.6 0.6 no signal
411 Flank Pain 46 0.6 0.6 no signal
412 Injection Site Discharge 25 0.6 0.6 no signal
413 Colitis Microscopic 23 0.6 0.6 no signal
414 Intentional Dose Omission 134 0.6 0.6 no signal
415 Rash Macular 170 0.6 0.6 no signal
416 Headache 3,055 0.6 0.6 no signal
417 Muscle Injury 40 0.6 0.6 no signal
418 Therapeutic Product Effect Decreased 215 0.6 0.6 no signal
419 Prostatomegaly 19 0.6 0.6 no signal
420 Limb Injury 131 0.6 0.6 no signal
421 Hospitalisation 736 0.6 0.6 no signal
422 Pain In Jaw 136 0.6 0.6 no signal
423 Feeling Cold 133 0.6 0.6 no signal
424 Wheezing 281 0.6 0.6 no signal
425 Weight Increased 1,056 0.6 0.6 no signal
426 Atrial Fibrillation 462 0.6 0.6 no signal
427 Intracranial Aneurysm 19 0.6 0.6 no signal
428 Pollakiuria 197 0.6 0.6 no signal
429 Deafness Unilateral 26 0.6 0.6 no signal
430 Vertigo 288 0.6 0.6 no signal
431 Skin Laceration 51 0.6 0.6 no signal
432 Dialysis 67 0.6 0.6 no signal
433 Asthenia 1,768 0.6 0.6 no signal
434 Flatulence 265 0.6 0.6 no signal
435 Liquid Product Physical Issue 33 0.6 0.6 no signal
436 Urinary Tract Disorder 21 0.6 0.6 no signal
437 Rotator Cuff Syndrome 60 0.6 0.6 no signal
438 Food Craving 23 0.6 0.6 no signal
439 Neuropathy Peripheral 438 0.6 0.6 no signal
440 Acute Myocardial Infarction 137 0.6 0.6 no signal
441 Spinal Pain 54 0.6 0.6 no signal
442 Thyroid Disorder 71 0.6 0.6 no signal
443 Abdominal Discomfort 768 0.6 0.6 no signal
444 Abdominal Pain Upper 942 0.6 0.6 no signal
445 Gastric Disorder 159 0.6 0.6 no signal
446 Off Label Use 3,936 0.6 0.6 no signal
447 Mouth Swelling 26 0.6 0.6 no signal
448 Irritable Bowel Syndrome 96 0.6 0.6 no signal
449 Rash 1,944 0.6 0.6 no signal
450 Foot Operation 22 0.6 0.6 no signal
451 Sputum Discoloured 42 0.6 0.6 no signal
452 Peripheral Coldness 61 0.6 0.6 no signal
453 Pruritus 1,670 0.6 0.6 no signal
454 Dermatitis Contact 50 0.6 0.6 no signal
455 Cataract 261 0.6 0.6 no signal
456 Cholecystectomy 50 0.6 0.6 no signal
457 Respiratory Tract Infection 114 0.6 0.6 no signal
458 Malaise 1,925 0.6 0.6 no signal
459 Parosmia 33 0.6 0.6 no signal
460 Tendon Rupture 54 0.6 0.6 no signal
461 Dry Mouth 352 0.6 0.6 no signal
462 Hepatic Enzyme Increased 295 0.6 0.6 no signal
463 Autoimmune Hepatitis 30 0.6 0.6 no signal
464 Renal Disorder 202 0.6 0.6 no signal
465 Bursitis 52 0.6 0.6 no signal
466 Hypoaesthesia 645 0.6 0.6 no signal
467 Herpes Zoster 247 0.6 0.6 no signal
468 Tendon Disorder 28 0.6 0.6 no signal
469 Accident 51 0.6 0.6 no signal
470 Hordeolum 18 0.6 0.6 no signal
471 Feeling Of Body Temperature Change 25 0.6 0.6 no signal
472 Gastroenteritis 62 0.6 0.6 no signal
473 Back Injury 46 0.6 0.6 no signal
474 Intervertebral Disc Protrusion 93 0.5 0.5 no signal
475 Food Allergy 32 0.5 0.5 no signal
476 Eructation 80 0.5 0.5 no signal
477 Cognitive Disorder 195 0.5 0.5 no signal
478 Product Prescribing Error 99 0.5 0.5 no signal
479 Prostatic Disorder 23 0.5 0.5 no signal
480 Gastroenteritis Viral 75 0.5 0.5 no signal
481 Cold Sweat 73 0.5 0.5 no signal
482 Sleep Disorder 289 0.5 0.5 no signal
483 Refusal Of Treatment By Patient 27 0.5 0.5 no signal
484 Feeling Hot 253 0.5 0.5 no signal
485 Chromaturia 93 0.5 0.5 no signal
486 Cardiovascular Disorder 105 0.5 0.5 no signal
487 Discomfort 248 0.5 0.5 no signal
488 Dyspnoea 2,302 0.5 0.5 no signal
489 Cheilitis 22 0.5 0.5 no signal
490 Skin Abrasion 19 0.5 0.5 no signal
491 Myasthenia Gravis 32 0.5 0.5 no signal
492 Abdominal Distension 422 0.5 0.5 no signal
493 Ocular Discomfort 44 0.5 0.5 no signal
494 Urinary Tract Infection 687 0.5 0.5 no signal
495 Diabetic Neuropathy 20 0.5 0.5 no signal
496 Paraesthesia 633 0.5 0.5 no signal
497 Diarrhoea 2,575 0.5 0.5 no signal
498 Choking Sensation 22 0.5 0.5 no signal
499 Hypertension 848 0.5 0.5 no signal
500 Tooth Fracture 44 0.5 0.5 no signal
501 Gastrointestinal Inflammation 31 0.5 0.5 no signal
502 Poor Quality Device Used 35 0.5 0.5 no signal
503 Eye Swelling 147 0.5 0.5 no signal
504 Scab 45 0.5 0.5 no signal
505 Spinal Column Stenosis 19 0.5 0.5 no signal
506 Chills 464 0.5 0.5 no signal
507 Multiple Allergies 31 0.5 0.5 no signal
508 Pancreatitis 209 0.5 0.5 no signal
509 Food Poisoning 21 0.5 0.5 no signal
510 Cystitis 126 0.5 0.5 no signal
511 Ventricular Extrasystoles 41 0.5 0.5 no signal
512 Pharyngitis 49 0.5 0.5 no signal
513 Restless Legs Syndrome 71 0.5 0.5 no signal
514 Deafness 101 0.5 0.5 no signal
515 Night Sweats 124 0.5 0.5 no signal
516 Appetite Disorder 25 0.5 0.5 no signal
517 Swelling 358 0.5 0.5 no signal
518 Anal Incontinence 34 0.5 0.5 no signal
519 Blood Glucose Decreased 184 0.5 0.5 no signal
520 Gastrointestinal Disorder 337 0.5 0.5 no signal
521 Spinal Disorder 36 0.5 0.5 no signal
522 Blood Urine Present 72 0.5 0.5 no signal
523 Grip Strength Decreased 33 0.5 0.5 no signal
524 Palpitations 441 0.5 0.5 no signal
525 Skin Discolouration 173 0.5 0.5 no signal
526 Thirst 67 0.5 0.5 no signal
527 Thinking Abnormal 70 0.5 0.5 no signal
528 Faeces Soft 27 0.5 0.5 no signal
529 Ear Infection 99 0.5 0.5 no signal
530 Lymphadenopathy 132 0.5 0.5 no signal
531 Kidney Infection 73 0.5 0.5 no signal
532 Bladder Disorder 37 0.5 0.5 no signal
533 Extrasystoles 26 0.5 0.5 no signal
534 Heart Rate Irregular 84 0.5 0.5 no signal
535 Dry Eye 179 0.5 0.5 no signal
536 Nerve Injury 41 0.5 0.5 no signal
537 Increased Appetite 69 0.5 0.5 no signal
538 Sleep Apnoea Syndrome 70 0.5 0.5 no signal
539 Breast Pain 39 0.5 0.5 no signal
540 Stress 263 0.5 0.5 no signal
541 Cardiac Valve Disease 21 0.5 0.5 no signal
542 Joint Swelling 439 0.5 0.5 no signal
543 Hunger 49 0.5 0.5 no signal
544 Blood Uric Acid Increased 21 0.5 0.5 no signal
545 Gastritis 95 0.5 0.5 no signal
546 Pharyngitis Streptococcal 39 0.5 0.5 no signal
547 Joint Injury 77 0.5 0.5 no signal
548 Hot Flush 271 0.5 0.5 no signal
549 Sars-cov-2 Test Positive 48 0.5 0.5 no signal
550 Mental Impairment 87 0.5 0.5 no signal
551 Post Procedural Infection 29 0.5 0.5 no signal
552 Loss Of Personal Independence In Daily Activities 170 0.5 0.5 no signal
553 Tongue Disorder 26 0.5 0.5 no signal
554 Hypersomnia 102 0.5 0.5 no signal
555 Bronchospasm 51 0.5 0.5 no signal
556 Glomerular Filtration Rate Decreased 43 0.5 0.5 no signal
557 Cholecystitis Acute 20 0.5 0.5 no signal
558 Post Procedural Complication 68 0.5 0.5 no signal
559 Tooth Extraction 44 0.5 0.5 no signal
560 Covid-19 624 0.5 0.5 no signal
561 Skin Swelling 30 0.5 0.5 no signal
562 Toe Amputation 18 0.5 0.5 no signal
563 Incorrect Dose Administered 791 0.5 0.5 no signal
564 Balance Disorder 304 0.5 0.5 no signal
565 Hyperaesthesia 29 0.5 0.5 no signal
566 Hyperlipidaemia 42 0.5 0.5 no signal
567 Application Site Pain 77 0.5 0.5 no signal
568 Immune System Disorder 46 0.5 0.5 no signal
569 Weight Decreased 975 0.5 0.4 no signal
570 Blood Disorder 28 0.5 0.5 no signal
571 Carpal Tunnel Syndrome 49 0.5 0.5 no signal
572 Decreased Immune Responsiveness 34 0.5 0.5 no signal
573 Neoplasm Malignant 231 0.4 0.4 no signal
574 Formication 24 0.4 0.4 no signal
575 Migraine 326 0.4 0.4 no signal
576 Hyperhidrosis 443 0.4 0.4 no signal
577 Drug Dispensing Error 53 0.4 0.4 no signal
578 Wrist Fracture 41 0.4 0.4 no signal
579 Facial Paralysis 29 0.4 0.4 no signal
580 Nephrolithiasis 156 0.4 0.4 no signal
581 Alopecia 671 0.4 0.4 no signal
582 Drug Intolerance 328 0.4 0.4 no signal
583 Viral Infection 113 0.4 0.4 no signal
584 Blepharospasm 21 0.4 0.4 no signal
585 Energy Increased 20 0.4 0.4 no signal
586 Bedridden 44 0.4 0.4 no signal
587 Epistaxis 251 0.4 0.4 no signal
588 Blood Potassium Increased 54 0.4 0.4 no signal
589 Skin Atrophy 19 0.4 0.4 no signal
590 Gastrooesophageal Reflux Disease 265 0.4 0.4 no signal
591 Upper Limb Fracture 66 0.4 0.4 no signal
592 Gallbladder Disorder 59 0.4 0.4 no signal
593 Device Use Issue 57 0.4 0.4 no signal
594 Spinal Osteoarthritis 29 0.4 0.4 no signal
595 Head Injury 103 0.4 0.4 no signal
596 Vision Blurred 444 0.4 0.4 no signal
597 Dysgeusia 242 0.4 0.4 no signal
598 Poor Quality Sleep 69 0.4 0.4 no signal
599 Erectile Dysfunction 83 0.4 0.4 no signal
600 Dyspepsia 316 0.4 0.4 no signal
601 Glaucoma 62 0.4 0.4 no signal
602 Choking 62 0.4 0.4 no signal
603 Nausea 2,515 0.4 0.4 no signal
604 Hiccups 26 0.4 0.4 no signal
605 Vitreous Floaters 31 0.4 0.4 no signal
606 Dysphagia 301 0.4 0.4 no signal
607 Dysuria 117 0.4 0.4 no signal
608 Impaired Work Ability 68 0.4 0.4 no signal
609 Impaired Driving Ability 36 0.4 0.4 no signal
610 Spinal Fracture 63 0.4 0.4 no signal
611 Bone Disorder 58 0.4 0.4 no signal
612 Eye Pruritus 104 0.4 0.4 no signal
613 Incorrect Product Storage 42 0.4 0.4 no signal
614 Feeling Jittery 60 0.4 0.4 no signal
615 Blood Thyroid Stimulating Hormone Increased 29 0.4 0.4 no signal
616 Myocardial Ischaemia 36 0.4 0.4 no signal
617 Oral Disorder 23 0.4 0.4 no signal
618 Skin Reaction 44 0.4 0.4 no signal
619 Therapeutic Product Effect Incomplete 220 0.4 0.4 no signal
620 Insurance Issue 46 0.4 0.4 no signal
621 Mitral Valve Incompetence 35 0.4 0.4 no signal
622 Micturition Urgency 35 0.4 0.4 no signal
623 Impaired Gastric Emptying 39 0.4 0.4 no signal
624 Internal Haemorrhage 35 0.4 0.4 no signal
625 Haemorrhagic Stroke 24 0.4 0.4 no signal
626 Heart Rate Increased 302 0.4 0.4 no signal
627 Ligament Sprain 30 0.4 0.4 no signal
628 Lower Limb Fracture 58 0.4 0.4 no signal
629 Joint Effusion 21 0.4 0.4 no signal
630 Oral Herpes 59 0.4 0.4 no signal
631 Blood Pressure Fluctuation 73 0.4 0.4 no signal
632 Poor Quality Product Administered 31 0.4 0.4 no signal
633 Prostatic Specific Antigen Increased 42 0.4 0.4 no signal
634 Blood Magnesium Decreased 26 0.4 0.4 no signal
635 Intervertebral Disc Degeneration 28 0.4 0.4 no signal
636 Coronavirus Infection 20 0.4 0.4 no signal
637 Aphthous Ulcer 23 0.4 0.4 no signal
638 Muscle Twitching 69 0.4 0.4 no signal
639 Fall 990 0.4 0.4 no signal
640 Quality Of Life Decreased 40 0.4 0.4 no signal
641 Dermatitis Acneiform 18 0.4 0.4 no signal
642 Dermatitis Allergic 37 0.4 0.4 no signal
643 Hip Fracture 95 0.4 0.4 no signal
644 Tooth Infection 39 0.4 0.4 no signal
645 Abnormal Loss Of Weight 20 0.4 0.4 no signal
646 Eye Pain 163 0.4 0.4 no signal
647 Road Traffic Accident 123 0.4 0.4 no signal
648 Temperature Intolerance 30 0.4 0.4 no signal
649 Type 2 Diabetes Mellitus 99 0.4 0.4 no signal
650 Hypercholesterolaemia 28 0.4 0.4 no signal
651 Faeces Discoloured 63 0.4 0.4 no signal
652 Lymphoedema 20 0.4 0.4 no signal
653 Gingival Pain 23 0.4 0.4 no signal
654 Disturbance In Attention 156 0.4 0.4 no signal
655 Vitamin D Deficiency 28 0.4 0.4 no signal
656 Incorrect Route Of Drug Administration 104 0.4 0.4 no signal
657 Frequent Bowel Movements 77 0.4 0.4 no signal
658 Arrhythmia 135 0.4 0.4 no signal
659 Atrioventricular Block 22 0.4 0.4 no signal
660 Cerebral Infarction 69 0.4 0.4 no signal
661 Localised Infection 68 0.4 0.4 no signal
662 Extra Dose Administered 112 0.4 0.4 no signal
663 Insomnia 748 0.4 0.4 no signal
664 Oral Discomfort 39 0.4 0.4 no signal
665 Drug Hypersensitivity 543 0.4 0.4 no signal
666 Brain Injury 28 0.4 0.4 no signal
667 Lip Dry 25 0.4 0.4 no signal
668 Blister 156 0.4 0.4 no signal
669 Panic Reaction 20 0.4 0.4 no signal
670 Ankle Fracture 43 0.4 0.4 no signal
671 Fluid Retention 141 0.4 0.4 no signal
672 Nephrotic Syndrome 19 0.4 0.4 no signal
673 Skin Disorder 92 0.4 0.4 no signal
674 Nail Disorder 24 0.4 0.4 no signal
675 Nodule 36 0.4 0.4 no signal
676 Hospice Care 27 0.4 0.4 no signal
677 Tooth Abscess 28 0.4 0.4 no signal
678 Asthma 305 0.4 0.4 no signal
679 Angioedema 120 0.4 0.4 no signal
680 Blindness 110 0.3 0.3 no signal
681 Taste Disorder 54 0.3 0.3 no signal
682 Eye Haemorrhage 36 0.3 0.3 no signal
683 Tremor 447 0.3 0.3 no signal
684 Vitamin D Decreased 23 0.3 0.3 no signal
685 Hypokinesia 39 0.3 0.3 no signal
686 Cholelithiasis 88 0.3 0.3 no signal
687 Skin Ulcer 69 0.3 0.3 no signal
688 Postoperative Wound Infection 18 0.3 0.3 no signal
689 Feeding Disorder 53 0.3 0.3 no signal
690 Tricuspid Valve Incompetence 21 0.3 0.3 no signal
691 Blood Pressure Systolic Increased 52 0.3 0.3 no signal
692 Furuncle 21 0.3 0.3 no signal
693 Impaired Quality Of Life 38 0.3 0.3 no signal
694 Tooth Disorder 59 0.3 0.3 no signal
695 Atrial Flutter 21 0.3 0.3 no signal
696 Hernia 50 0.3 0.3 no signal
697 Product Distribution Issue 23 0.3 0.3 no signal
698 Weight Fluctuation 27 0.3 0.3 no signal
699 Speech Disorder 135 0.3 0.3 no signal
700 Gastrointestinal Infection 23 0.3 0.3 no signal
701 Liver Disorder 114 0.3 0.3 no signal
702 Chronic Obstructive Pulmonary Disease 134 0.3 0.3 no signal
703 Hysterectomy 22 0.3 0.3 no signal
704 Joint Range Of Motion Decreased 34 0.3 0.3 no signal
705 Diplopia 66 0.3 0.3 no signal
706 Hand Fracture 18 0.3 0.3 no signal
707 Fungal Infection 84 0.3 0.3 no signal
708 Confusional State 407 0.3 0.3 no signal
709 Erythema 511 0.3 0.3 no signal
710 Constipation 538 0.3 0.3 no signal
711 Sensitive Skin 18 0.3 0.3 no signal
712 Alanine Aminotransferase Increased 151 0.3 0.3 no signal
713 Rhabdomyolysis 102 0.3 0.3 no signal
714 Osteoarthritis 104 0.3 0.3 no signal
715 Oral Pain 55 0.3 0.3 no signal
716 Abnormal Dreams 68 0.3 0.3 no signal
717 Inflammation 125 0.3 0.3 no signal
718 Photosensitivity Reaction 40 0.3 0.3 no signal
719 Flushing 245 0.3 0.3 no signal
720 Hiatus Hernia 31 0.3 0.3 no signal
721 Aphasia 72 0.3 0.3 no signal
722 Abdominal Pain 551 0.3 0.3 no signal
723 Blood Pressure Decreased 157 0.3 0.3 no signal
724 Paralysis 34 0.3 0.3 no signal
725 Ageusia 59 0.3 0.3 no signal
726 Covid-19 Pneumonia 28 0.3 0.3 no signal
727 Pulmonary Mass 35 0.3 0.3 no signal
728 Heart Rate Decreased 83 0.3 0.3 no signal
729 Hyperthyroidism 34 0.3 0.3 no signal
730 Blood Urea Increased 39 0.3 0.3 no signal
731 Respiratory Syncytial Virus Infection 20 0.3 0.3 no signal
732 Eczema 116 0.3 0.3 no signal
733 Retching 49 0.3 0.3 no signal
734 Anxiety 657 0.3 0.3 no signal
735 Pneumonia 739 0.3 0.3 no signal
736 Procedural Pain 63 0.3 0.3 no signal
737 Anosmia 33 0.3 0.3 no signal
738 Generalised Oedema 28 0.3 0.3 no signal
739 Product Packaging Issue 21 0.3 0.3 no signal
740 Renal Cyst 18 0.3 0.3 no signal
741 Decreased Activity 24 0.3 0.3 no signal
742 Hypertensive Crisis 25 0.3 0.3 no signal
743 Dermatitis 46 0.3 0.3 no signal
744 Syncope 221 0.3 0.3 no signal
745 Nervous System Disorder 69 0.3 0.3 no signal
746 Pulmonary Thrombosis 24 0.3 0.3 no signal
747 Supraventricular Tachycardia 21 0.3 0.3 no signal
748 Haematoma 57 0.3 0.3 no signal
749 Cardiac Murmur 19 0.3 0.3 no signal
750 Device Delivery System Issue 57 0.3 0.3 no signal
751 Therapy Change 21 0.3 0.3 no signal
752 Incontinence 23 0.3 0.3 no signal
753 Sensory Disturbance 35 0.3 0.3 no signal
754 Wound 60 0.3 0.3 no signal
755 Eye Irritation 120 0.3 0.3 no signal
756 Depressed Mood 113 0.3 0.3 no signal
757 Cardiac Failure Congestive 173 0.3 0.3 no signal
758 Blindness Unilateral 30 0.3 0.3 no signal
759 Abdominal Pain Lower 54 0.3 0.3 no signal
760 Leukaemia 20 0.3 0.3 no signal
761 Decreased Appetite 491 0.3 0.3 no signal
762 Body Temperature Decreased 21 0.3 0.3 no signal
763 Petechiae 22 0.3 0.3 no signal
764 Aspartate Aminotransferase Increased 112 0.3 0.3 no signal
765 Salivary Hypersecretion 21 0.3 0.3 no signal
766 Nightmare 73 0.3 0.3 no signal
767 Laceration 20 0.3 0.3 no signal
768 Disorientation 83 0.3 0.3 no signal
769 Cellulitis 105 0.3 0.3 no signal
770 Emphysema 21 0.3 0.3 no signal
771 Lower Respiratory Tract Infection 94 0.3 0.3 no signal
772 Depression 473 0.3 0.3 no signal
773 Urinary Incontinence 61 0.3 0.3 no signal
774 Cardiac Failure 165 0.3 0.3 no signal
775 Loss Of Consciousness 263 0.3 0.3 no signal
776 Middle Insomnia 38 0.3 0.3 no signal
777 Blood Iron Decreased 24 0.3 0.3 no signal
778 Product Odour Abnormal 21 0.3 0.3 no signal
779 Skin Exfoliation 168 0.3 0.3 no signal
780 Incorrect Product Administration Duration 41 0.3 0.3 no signal
781 Cyst 25 0.3 0.3 no signal
782 Hypothyroidism 64 0.3 0.3 no signal
783 Bacterial Infection 37 0.3 0.3 no signal
784 Thrombosis 160 0.3 0.3 no signal
785 Foot Deformity 22 0.3 0.3 no signal
786 Lung Disorder 97 0.3 0.3 no signal
787 Hypophagia 50 0.3 0.3 no signal
788 Dehydration 262 0.3 0.3 no signal
789 Eye Infection 22 0.3 0.3 no signal
790 Retinal Detachment 18 0.3 0.3 no signal
791 Impaired Healing 64 0.3 0.3 no signal
792 Rib Fracture 40 0.3 0.3 no signal
793 Foot Fracture 37 0.3 0.3 no signal
794 Device Leakage 82 0.3 0.3 no signal
795 Blood Potassium Decreased 58 0.2 0.2 no signal
796 Therapy Partial Responder 29 0.2 0.2 no signal
797 Muscle Rigidity 23 0.2 0.2 no signal
798 Diabetes Mellitus Inadequate Control 34 0.2 0.2 no signal
799 Abasia 48 0.2 0.2 no signal
800 Therapeutic Response Decreased 115 0.2 0.2 no signal
801 Nocturia 23 0.2 0.2 no signal
802 Anaphylactic Reaction 104 0.2 0.2 no signal
803 Renal Impairment 158 0.2 0.2 no signal
804 Glossodynia 42 0.2 0.2 no signal
805 Colon Cancer 28 0.2 0.2 no signal
806 Photophobia 35 0.2 0.2 no signal
807 Eating Disorder 40 0.2 0.2 no signal
808 Sudden Death 20 0.2 0.2 no signal
809 Drug Administered At Inappropriate Site 20 0.2 0.2 no signal
810 Libido Decreased 23 0.2 0.2 no signal
811 Skin Fissures 35 0.2 0.2 no signal
812 Pyrexia 637 0.2 0.2 no signal
813 Orthostatic Hypotension 32 0.2 0.2 no signal
814 Drug Effect Decreased 100 0.2 0.2 no signal
815 Irritability 110 0.2 0.2 no signal
816 Erythema Multiforme 17 0.2 0.2 no signal
817 Hepatomegaly 18 0.2 0.2 no signal
818 Osteoporosis 75 0.2 0.2 no signal
819 Lung Neoplasm Malignant 75 0.2 0.2 no signal
820 Diarrhoea Haemorrhagic 17 0.2 0.2 no signal
821 Lymphoma 28 0.2 0.2 no signal
822 Joint Dislocation 19 0.2 0.2 no signal
823 Red Blood Cell Sedimentation Rate Increased 20 0.2 0.2 no signal
824 Eye Inflammation 17 0.2 0.2 no signal
825 Vasculitis 21 0.2 0.2 no signal
826 Fracture 34 0.2 0.2 no signal
827 Hypotonia 18 0.2 0.2 no signal
828 Apathy 26 0.2 0.2 no signal
829 Dry Skin 234 0.2 0.2 no signal
830 Oral Candidiasis 23 0.2 0.2 no signal
831 Polyneuropathy 21 0.2 0.2 no signal
832 Skin Cancer 38 0.2 0.2 no signal
833 Ventricular Tachycardia 29 0.2 0.2 no signal
834 Scar 30 0.2 0.2 no signal
835 Ischaemic Stroke 31 0.2 0.2 no signal
836 Hyperglycaemia 63 0.2 0.2 no signal
837 Fear 47 0.2 0.2 no signal
838 Mental Disorder 75 0.2 0.2 no signal
839 Post Procedural Haemorrhage 20 0.2 0.2 no signal
840 Ocular Hyperaemia 80 0.2 0.2 no signal
841 Death 1,473 0.2 0.2 no signal
842 Obesity 27 0.2 0.2 no signal
843 Vomiting 790 0.2 0.2 no signal
844 Product Use Complaint 26 0.2 0.2 no signal
845 Initial Insomnia 17 0.2 0.2 no signal
846 Eye Discharge 17 0.2 0.2 no signal
847 Somnolence 332 0.2 0.2 no signal
848 Restlessness 60 0.2 0.2 no signal
849 Ulcer 26 0.2 0.2 no signal
850 Hair Texture Abnormal 22 0.2 0.2 no signal
851 Dental Caries 18 0.2 0.2 no signal
852 Product Prescribing Issue 33 0.2 0.2 no signal
853 Dysarthria 61 0.2 0.2 no signal
854 Colitis 61 0.2 0.2 no signal
855 Skin Infection 18 0.2 0.2 no signal
856 Platelet Count Increased 21 0.2 0.2 no signal
857 Lung Infection 25 0.2 0.2 no signal
858 Conjunctivitis 29 0.2 0.2 no signal
859 Expired Product Administered 52 0.2 0.2 no signal
860 Blood Creatinine Increased 102 0.2 0.2 no signal
861 Pain Of Skin 42 0.2 0.2 no signal
862 Hepatic Cirrhosis 29 0.2 0.2 no signal
863 Sexual Dysfunction 18 0.2 0.2 no signal
864 Hypotension 305 0.2 0.2 no signal
865 Application Site Erythema 40 0.2 0.2 no signal
866 Intraocular Pressure Increased 19 0.2 0.2 no signal
867 Pancreatitis Acute 33 0.2 0.2 no signal
868 Neoplasm 17 0.2 0.2 no signal
869 Systemic Lupus Erythematosus 52 0.2 0.2 no signal
870 Ankylosing Spondylitis 19 0.2 0.2 no signal
871 Liver Injury 35 0.2 0.2 no signal
872 Sinus Bradycardia 14 0.2 0.2 no signal
873 Pericarditis 24 0.2 0.2 no signal
874 Candida Infection 24 0.2 0.2 no signal
875 Blood Sodium Decreased 27 0.2 0.2 no signal
876 Chronic Kidney Disease 110 0.2 0.2 no signal
877 Pericardial Effusion 33 0.2 0.2 no signal
878 Pelvic Pain 26 0.2 0.2 no signal
879 Immunodeficiency 21 0.2 0.2 no signal
880 Full Blood Count Abnormal 15 0.2 0.2 no signal
881 Oedema 77 0.2 0.2 no signal
882 Blood Calcium Decreased 16 0.2 0.2 no signal
883 Malignant Melanoma 19 0.2 0.2 no signal
884 Product Dose Omission In Error 38 0.2 0.2 no signal
885 Brain Neoplasm 13 0.2 0.2 no signal
886 Urosepsis 13 0.2 0.2 no signal
887 Product Physical Issue 28 0.2 0.2 no signal
888 Anaphylactic Shock 36 0.2 0.2 no signal
889 Rheumatoid Arthritis 158 0.2 0.2 no signal
890 Skin Lesion 38 0.2 0.2 no signal
891 Staphylococcal Infection 46 0.2 0.2 no signal
892 Eyelid Ptosis 14 0.2 0.2 no signal
893 Madarosis 16 0.2 0.2 no signal
894 Pulmonary Fibrosis 26 0.2 0.2 no signal
895 Cholecystitis 16 0.2 0.2 no signal
896 Mood Altered 36 0.2 0.2 no signal
897 Coeliac Disease 13 0.2 0.2 no signal
898 Infection 190 0.2 0.2 no signal
899 Liver Function Test Abnormal 38 0.2 0.2 no signal
900 Drug-induced Liver Injury 40 0.2 0.2 no signal
901 Psoriatic Arthropathy 52 0.2 0.2 no signal
902 Urinary Retention 43 0.2 0.2 no signal
903 Emotional Disorder 40 0.2 0.2 no signal
904 Panic Attack 47 0.2 0.2 no signal
905 Personality Change 12 0.2 0.2 no signal
906 Nephropathy 12 0.2 0.2 no signal
907 Squamous Cell Carcinoma 12 0.2 0.2 no signal
908 Haemorrhage 133 0.2 0.2 no signal
909 Body Temperature Increased 26 0.2 0.2 no signal
910 Stomatitis 77 0.2 0.2 no signal
911 Hypoglycaemia 61 0.2 0.2 no signal
912 Adrenal Insufficiency 15 0.2 0.2 no signal
913 Gingival Bleeding 17 0.2 0.2 no signal
914 C-reactive Protein Increased 45 0.2 0.2 no signal
915 Mouth Ulceration 26 0.2 0.2 no signal
916 Oedema Peripheral 151 0.2 0.2 no signal
917 White Blood Cell Count Increased 47 0.2 0.2 no signal
918 Sepsis 136 0.2 0.2 no signal
919 Complication Associated With Device 16 0.2 0.2 no signal
920 Gastric Ulcer 23 0.2 0.2 no signal
921 Skin Burning Sensation 85 0.2 0.2 no signal
922 Renal Failure 159 0.2 0.2 no signal
923 Drug Prescribing Error 23 0.2 0.2 no signal
924 Osteopenia 18 0.2 0.2 no signal
925 Treatment Noncompliance 64 0.2 0.2 no signal
926 Haemorrhoids 23 0.2 0.2 no signal
927 Ataxia 14 0.2 0.2 no signal
928 Subarachnoid Haemorrhage 12 0.2 0.2 no signal
929 Haematochezia 64 0.2 0.1 no signal
930 Pulmonary Oedema 52 0.1 0.1 no signal
931 Femur Fracture 36 0.1 0.1 no signal
932 Breast Cancer 108 0.1 0.1 no signal
933 Intestinal Obstruction 43 0.1 0.1 no signal
934 Coordination Abnormal 16 0.1 0.1 no signal
935 Drug Eruption 20 0.1 0.1 no signal
936 Cardiac Arrest 94 0.1 0.1 no signal
937 Therapeutic Response Shortened 36 0.1 0.1 no signal
938 Electrolyte Imbalance 13 0.1 0.1 no signal
939 Hemiparesis 19 0.1 0.1 no signal
940 Haemoptysis 31 0.1 0.1 no signal
941 Hepatic Function Abnormal 41 0.1 0.1 no signal
942 Infusion Site Pain 14 0.1 0.1 no signal
943 Vaginal Discharge 11 0.1 0.1 no signal
944 Tachycardia 97 0.1 0.1 no signal
945 Cerebral Haemorrhage 39 0.1 0.1 no signal
946 Basal Cell Carcinoma 17 0.1 0.1 no signal
947 Iron Deficiency Anaemia 10 0.1 0.1 no signal
948 Transaminases Increased 24 0.1 0.1 no signal
949 Haematuria 37 0.1 0.1 no signal
950 Device Occlusion 15 0.1 0.1 no signal
951 Appendicitis 10 0.1 0.1 no signal
952 Pleural Effusion 65 0.1 0.1 no signal
953 Folliculitis 11 0.1 0.1 no signal
954 Clostridium Difficile Infection 23 0.1 0.1 no signal
955 Anger 36 0.1 0.1 no signal
956 Hepatitis 27 0.1 0.1 no signal
957 Respiratory Distress 29 0.1 0.1 no signal
958 Psoriasis 137 0.1 0.1 no signal
959 Transfusion 11 0.1 0.1 no signal
960 Drug Ineffective 1,375 0.1 0.1 no signal
961 Subdural Haematoma 15 0.1 0.1 no signal
962 Eyelid Oedema 12 0.1 0.1 no signal
963 Splenomegaly 12 0.1 0.1 no signal
964 Coagulopathy 17 0.1 0.1 no signal
965 Movement Disorder 33 0.1 0.1 no signal
966 Oesophagitis 11 0.1 0.1 no signal
967 Prostate Cancer 81 0.1 0.1 no signal
968 Product Availability Issue 22 0.1 0.1 no signal
969 Helicobacter Infection 10 0.1 0.1 no signal
970 Skin Irritation 45 0.1 0.1 no signal
971 Rectal Haemorrhage 42 0.1 0.1 no signal
972 Cardiomegaly 12 0.1 0.1 no signal
973 Seizure 111 0.1 0.1 no signal
974 Pancreatic Carcinoma 28 0.1 0.1 no signal
975 Activities Of Daily Living Impaired 19 0.1 0.1 no signal
976 Acne 72 0.1 0.1 no signal
977 Osteomyelitis 17 0.1 0.1 no signal
978 Wound Infection 10 0.1 0.1 no signal
979 Product Packaging Quantity Issue 10 0.1 0.1 no signal
980 Inability To Afford Medication 9 0.1 0.1 no signal
981 Oxygen Saturation Decreased 51 0.1 0.1 no signal
982 Dyskinesia 37 0.1 0.1 no signal
983 Red Blood Cell Count Decreased 26 0.1 0.1 no signal
984 Hallucination 68 0.1 0.1 no signal
985 Crying 33 0.1 0.1 no signal
986 International Normalised Ratio Increased 26 0.1 0.1 no signal
987 Pulmonary Embolism 86 0.1 0.1 no signal
988 Small Intestinal Obstruction 11 0.1 0.1 no signal
989 Accidental Underdose 13 0.1 0.1 no signal
990 Uveitis 12 0.1 0.1 no signal
991 Hypothermia 9 0.1 0.1 no signal
992 Pallor 24 0.1 0.1 no signal
993 Mood Swings 28 0.1 0.1 no signal
994 Neutrophil Count Increased 9 0.1 0.1 no signal
995 Colitis Ulcerative 39 0.1 0.1 no signal
996 Anaemia 165 0.1 0.1 no signal
997 Gastric Haemorrhage 10 0.1 0.1 no signal
998 Condition Aggravated 260 0.1 0.1 no signal
999 Deep Vein Thrombosis 56 0.1 0.1 no signal
1000 Gamma-glutamyltransferase Increased 19 0.1 0.1 no signal
1001 Drug Resistance 22 0.1 0.1 no signal
1002 Prescribed Underdose 17 0.1 0.1 no signal
1003 Proteinuria 16 0.1 0.1 no signal
1004 Cardiogenic Shock 12 0.1 0.1 no signal
1005 Psychomotor Hyperactivity 14 0.1 0.1 no signal
1006 Contraindicated Product Administered 25 0.1 0.1 no signal
1007 Bradycardia 44 0.1 0.1 no signal
1008 Thyroid Cancer 10 0.1 0.1 no signal
1009 Product Taste Abnormal 11 0.1 0.1 no signal
1010 Agitation 60 0.1 0.1 no signal
1011 Inflammatory Bowel Disease 8 0.1 0.1 no signal
1012 Hallucination, Visual 17 0.1 0.1 no signal
1013 Malnutrition 9 0.1 0.1 no signal
1014 Gastrointestinal Haemorrhage 68 0.1 0.1 no signal
1015 Paranoia 14 0.1 0.1 no signal
1016 Ventricular Fibrillation 9 0.1 0.1 no signal
1017 Blood Alkaline Phosphatase Increased 20 0.1 0.1 no signal
1018 Application Site Rash 11 0.1 0.1 no signal
1019 Injury 56 0.1 0.1 no signal
1020 Product Use Issue 146 0.1 0.1 no signal
1021 Euphoric Mood 8 0.1 0.1 no signal
1022 Bladder Cancer 46 0.1 0.1 no signal
1023 Unintentional Medical Device Removal 9 0.1 0.1 no signal
1024 Face Oedema 13 0.1 0.1 no signal
1025 Intentional Product Use Issue 67 0.1 0.1 no signal
1026 Circulatory Collapse 13 0.1 0.1 no signal
1027 Ovarian Cancer 7 0.1 0.1 no signal
1028 Breast Cancer Female 20 0.1 0.1 no signal
1029 Cardiomyopathy 11 0.1 0.1 no signal
1030 Dermatitis Atopic 37 0.1 0.1 no signal
1031 Body Height Decreased 8 0.1 0.1 no signal
1032 General Physical Health Deterioration 85 0.1 0.1 no signal
1033 Intercepted Product Preparation Error 9 0.1 0.1 no signal
1034 Local Swelling 13 0.1 0.1 no signal
1035 Bipolar Disorder 8 0.1 0.1 no signal
1036 Bone Loss 11 0.1 0.1 no signal
1037 Stevens-johnson Syndrome 16 0.1 0.1 no signal
1038 Disease Recurrence 34 0.1 0.1 no signal
1039 Haemoglobin Decreased 73 0.1 0.1 no signal
1040 Ejection Fraction Decreased 11 0.1 0.1 no signal
1041 Blood Bilirubin Increased 19 0.1 0.1 no signal
1042 Haematocrit Decreased 14 0.1 0.1 no signal
1043 Suicidal Ideation 64 0.1 0.1 no signal
1044 Blood Lactate Dehydrogenase Increased 11 0.1 0.1 no signal
1045 Multiple Sclerosis 33 0.1 0.1 no signal
1046 Pneumonia Aspiration 17 0.1 0.1 no signal
1047 Melaena 15 0.1 0.1 no signal
1048 Acute Respiratory Distress Syndrome 12 0.1 0.1 no signal
1049 Poor Venous Access 7 0.1 0.1 no signal
1050 Device Deployment Issue 8 0.1 0.1 no signal
1051 Haemorrhage Intracranial 10 0.1 0.1 no signal
1052 Multiple Fractures 11 0.1 0.1 no signal
1053 Disease Progression 77 0.1 0.1 no signal
1054 Acute Kidney Injury 99 0.1 0.1 no signal
1055 Mental Status Changes 18 0.1 0.1 no signal
1056 Delusion 10 0.1 0.1 no signal
1057 Interstitial Lung Disease 31 0.1 0.1 no signal
1058 Product Complaint 16 0.1 0.1 no signal
1059 Epilepsy 19 0.1 0.1 no signal
1060 Hepatic Cancer 15 0.1 0.1 no signal
1061 Device Breakage 24 0.1 0.1 no signal
1062 Drug Interaction 95 0.1 0.1 no signal
1063 Ovarian Cyst 6 0.1 0.1 no signal
1064 Cardio-respiratory Arrest 25 0.1 0.1 no signal
1065 Toxic Skin Eruption 6 0.1 0.1 no signal
1066 Motor Dysfunction 6 0.1 0.1 no signal
1067 Jaundice 16 0.1 0.1 no signal
1068 Blood Count Abnormal 9 0.1 0.1 no signal
1069 Pulmonary Hypertension 12 0.1 0.1 no signal
1070 Multiple Organ Dysfunction Syndrome 16 0.1 0.1 no signal
1071 Skeletal Injury 6 0.1 0.1 no signal
1072 Application Site Pruritus 13 0.1 0.1 no signal
1073 Syringe Issue 10 0.1 0.1 no signal
1074 Ileus 7 0.1 0.1 no signal
1075 Hypercalcaemia 7 0.1 0.1 no signal
1076 Visual Acuity Reduced 19 0.1 0.1 no signal
1077 Hypokalaemia 26 0.1 0.1 no signal
1078 Lymphocyte Count Decreased 10 0.1 0.1 no signal
1079 Muscle Spasticity 7 0.1 0.1 no signal
1080 Pneumonitis 15 0.1 0.1 no signal
1081 Leukocytosis 10 0.1 0.1 no signal
1082 Hypoxia 19 0.1 0.1 no signal
1083 Respiratory Arrest 15 0.1 0.1 no signal
1084 Platelet Count Decreased 57 0.1 0.1 no signal
1085 Intestinal Perforation 6 0.1 0.1 no signal
1086 Renal Injury 16 0.1 0.1 no signal
1087 Tooth Loss 11 0.1 0.1 no signal
1088 Affect Lability 5 0.1 0.1 no signal
1089 White Blood Cell Count Decreased 56 0.1 0.1 no signal
1090 Acute Hepatic Failure 7 0.1 0.1 no signal
1091 Plasma Cell Myeloma 20 0.1 0.1 no signal
1092 Central Nervous System Lesion 7 0.1 0.1 no signal
1093 Abscess 8 0.1 0.1 no signal
1094 Pneumocystis Jirovecii Pneumonia 5 0.1 0.1 no signal
1095 Hepatic Failure 15 0.1 0.1 no signal
1096 Full Blood Count Decreased 10 0.1 0.1 no signal
1097 Vaginal Haemorrhage 21 0.1 0.1 no signal
1098 Accidental Overdose 18 0.1 0.1 no signal
1099 Hyperkalaemia 17 0.1 0.1 no signal
1100 Mania 8 0.1 0.1 no signal
1101 No Therapeutic Response 6 0.1 0.1 no signal
1102 Application Site Irritation 6 0.1 0.1 no signal
1103 Shock 11 0.1 0.1 no signal
1104 Poisoning 6 0.1 0.1 no signal
1105 Gastric Cancer 12 0.1 0.1 no signal
1106 Unresponsive To Stimuli 12 0.1 0.1 no signal
1107 Breast Cancer Metastatic 5 0.1 0.1 no signal
1108 Altered State Of Consciousness 10 0.1 0.1 no signal
1109 Product Use In Unapproved Indication 113 0.1 0.1 no signal
1110 Device Adhesion Issue 7 0.1 0.1 no signal
1111 Diabetic Ketoacidosis 11 0.1 0.1 no signal
1112 Hand Deformity 6 0.1 0.1 no signal
1113 Economic Problem 7 0.1 0.1 no signal
1114 Rebound Effect 5 0.1 0.1 no signal
1115 Psychotic Disorder 13 0.1 0.1 no signal
1116 Hallucination, Auditory 7 0.1 0.1 no signal
1117 Metastases To Lung 5 0.1 0.1 no signal
1118 Haematemesis 11 0.1 0.1 no signal
1119 Hepatic Encephalopathy 4 0.1 0.1 no signal
1120 Drug Administration Error 13 0.1 0.1 no signal
1121 Thrombocytopenia 46 0.1 0.1 no signal
1122 Hepatotoxicity 9 0.1 0.1 no signal
1123 Pemphigus 5 0.1 0.1 no signal
1124 Metastases To Liver 7 0.1 0.1 no signal
1125 Hair Colour Changes 5 0.1 0.1 no signal
1126 Respiratory Failure 29 0.1 0.1 no signal
1127 Hyponatraemia 22 0.1 0.1 no signal
1128 Metastases To Central Nervous System 5 0.1 0.1 no signal
1129 Mydriasis 5 0.1 0.1 no signal
1130 Hyperbilirubinaemia 4 0.1 0.1 no signal
1131 Maternal Exposure During Pregnancy 34 0.0 0.0 no signal
1132 Gynaecomastia 12 0.0 0.0 no signal
1133 Dysmenorrhoea 5 0.0 0.0 no signal
1134 Anhedonia 10 0.0 0.0 no signal
1135 Neutrophil Count Decreased 15 0.0 0.0 no signal
1136 Treatment Failure 30 0.0 0.0 no signal
1137 Dystonia 7 0.0 0.0 no signal
1138 Aggression 18 0.0 0.0 no signal
1139 Fistula 4 0.0 0.0 no signal
1140 Myocarditis 4 0.0 0.0 no signal
1141 Hepatocellular Injury 5 0.0 0.0 no signal
1142 Menorrhagia 7 0.0 0.0 no signal
1143 Oesophageal Carcinoma 10 0.0 0.0 no signal
1144 Renal Cancer 16 0.0 0.0 no signal
1145 Withdrawal Syndrome 14 0.0 0.0 no signal
1146 Product Substitution Issue 19 0.0 0.0 no signal
1147 Incorrect Drug Administration Duration 9 0.0 0.0 no signal
1148 Tuberculosis 4 0.0 0.0 no signal
1149 Parkinsonism 3 0.0 0.0 no signal
1150 Metastases To Bone 5 0.0 0.0 no signal
1151 Osteonecrosis 10 0.0 0.0 no signal
1152 Product Quality Issue 39 0.0 0.0 no signal
1153 Emotional Distress 35 0.0 0.0 no signal
1154 Hereditary Angioedema 3 0.0 0.0 no signal
1155 Bone Density Decreased 9 0.0 0.0 no signal
1156 Myelodysplastic Syndrome 4 0.0 0.0 no signal
1157 Abnormal Behaviour 11 0.0 0.0 no signal
1158 Meningioma 4 0.0 0.0 no signal
1159 Nephropathy Toxic 3 0.0 0.0 no signal
1160 Acute Myeloid Leukaemia 4 0.0 0.0 no signal
1161 Hepatic Cytolysis 3 0.0 0.0 no signal
1162 Peritonitis 5 0.0 0.0 no signal
1163 Osteonecrosis Of Jaw 5 0.0 0.0 no signal
1164 Abortion Spontaneous 8 0.0 0.0 no signal
1165 Overdose 43 0.0 0.0 no signal
1166 Multiple Sclerosis Relapse 13 0.0 0.0 no signal
1167 Metrorrhagia 3 0.0 0.0 no signal
1168 Drug Effective For Unapproved Indication 5 0.0 0.0 no signal
1169 No Adverse Event 27 0.0 0.0 no signal
1170 Menstruation Irregular 4 0.0 0.0 no signal
1171 Intentional Self-injury 3 0.0 0.0 no signal
1172 Tardive Dyskinesia 4 0.0 0.0 no signal
1173 Device Dislocation 6 0.0 0.0 no signal
1174 Product Adhesion Issue 3 0.0 0.0 no signal
1175 Colorectal Cancer 3 0.0 0.0 no signal
1176 Device Expulsion 3 0.0 0.0 no signal