OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Low Density Lipoprotein Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,597 reports · 247 co-occurring drugs

As of the last recalculation, Low Density Lipoprotein Increased appears in 7,597 FAERS reports alongside 247 co-occurring drug terms. The strongest observed disproportionality signal is INCLISIRAN (PRR 184.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Inclisiran503184.0196.3
Alirocumab35640.841.3
Evolocumab1,17023.223.3
Ezetimibe56922.422.6
Rosuvastatin79611.811.8
Pitavastatin Calcium359.49.4
Icosapent Ethyl278.78.7
Niacin337.87.8
Gemfibrozil427.67.6
Atorvastatin Calcium6357.67.6
Vitamin E786.96.9
Rosuvastatin Calcium636.26.2
Ezetimibe And Simvastatin325.85.8
Abacavir Sulfate205.65.6
Asfotase Alfa205.55.5
Olanzapine Pamoate815.55.5
Lopinavir And Ritonavir265.35.3
Ritonavir 100 Mg275.05.0
Efavirenz194.74.7
Fenofibrate604.74.7
Fingolimod Hcl1414.54.5
Valsartan And Hydrochlorothiazide224.44.5
Basiliximab194.44.4
Isotretinoin784.44.4
Amlodipine Besylate And Benazepril Hydrochloride144.24.2
Telmisartan274.24.2
Nilotinib434.04.0
Lamivudine454.04.0
Atorvastatin Calcium, Film Coated1003.93.9
Lamivudine Oral363.93.9
Tenofovir Disoproxil Fumarate Tablets123.83.8
Chlorthalidone163.83.8
Febuxostat Tablets 40 Mg143.83.8
Febuxostat Tablets 80 Mg143.83.8
Lisinopril And Hydrochlorothiazide143.83.8
Fish Oil1213.73.7
Zidovudine183.73.7
Canagliflozin403.73.7
Ascorbic Acid303.53.5
Ticagrelor413.53.5
Clobetasol Propionate Ointment Usp, 0.05%133.53.5
Clobetasol Propionate133.43.5
Dapagliflozin393.43.4
Pravastatin Sodium243.33.3
Carisoprodol233.33.3
Ritonavir353.33.3
Atazanavir173.23.2
Prasugrel Hydrochloride123.23.2
Raloxifene Hydrochloride173.23.2
Lisinopril And Hydrochlorothiazide Tablets93.13.1
Darunavir173.13.1
Torsemide373.13.1
Losartan Potassium And Hydrochlorothiazide133.13.1
Testosterone263.13.1
Valsartan1153.03.0
Amlodipine Besylate And Valsartan123.03.0
Calcium Gluconate133.03.0
Sodium Bicarbonate253.03.0
Sodium Bicarbonate Injection,253.03.0
Upadacitinib872.92.9
Olanzapine1132.92.9
Indapamide192.92.9
Simvastatin2592.92.9
Lovastatin272.92.9
Theophylline Anhydrous132.92.9
Theophylline122.92.9
Baricitinib102.82.8
Aspirin 325 Mg5072.82.8
Aspirin 81 Mg5072.82.8
Alendronate Sodium Tablet192.82.8
Promethazine Hydrochloride192.82.8
Atenolol1342.82.8
Febuxostat172.82.8
Aspirin5212.82.8
Enalapril Maleate252.82.8
Testosterone Cypionate92.82.8
Tolterodine Tartrate92.72.8
Nevirapine92.72.7
Linagliptin182.72.7
Clopidogrel1922.72.7
Nifedipine462.72.7
Insulin542.72.7
Aripiprazole Oral402.72.7
Aripiprazole Orally Disintegrating402.72.7
Insulin Glargine-Yfgn212.62.6
Hydrochlorothiazide1382.62.6
Nitroglycerin512.62.6
Olmesartan Medoxomil342.62.6
Butalbital, Acetaminophen, And Caffeine102.62.6
Eplerenone122.62.6
Ketoconazole162.52.5
Nebivolol Hydrochloride312.52.5
Liothyronine Sodium82.52.5
Levothyroxine Sodium2822.52.5
Anastrozole332.52.5
Estradiol772.52.5
Clotrimazole112.52.5
Amlodipine Besylate1302.52.5
Lanreotide Acetate72.42.4
Cyclobenzaprine Hydrochloride82.42.4
Metformin Hcl492.42.4
Exemestane192.42.4
Quinapril Hydrochloride72.42.4
Dolutegravir Sodium82.42.4
Tizanidine Hydrochloride162.42.4
Emtricitabine And Tenofovir Alafenamide102.42.4
Pioglitazone382.42.4
Loratadine And Pseudoephedrine Sulfate72.42.4
Ketoconazole Foam132.42.4
Estrogens, Conjugated522.42.4
Losartan Potassium692.42.4
Conjugated Estrogens512.42.4
Ketoconazole Cream, 2%132.42.4
Isosorbide Dinitrate172.42.4
Biotin272.42.4
Drs. Clotrimazole102.42.4
Family Wellness Clotrimazole102.42.4
Clotrimazole Topical102.42.4
Valsartan Oral462.32.3
Glimepiride332.32.3
Lubiprostone82.32.3
Mycophenolic Acid272.32.3
Candesartan Cilexetil222.32.3
Tofacitinib1512.32.3
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl412.32.3
Multivitamin412.32.3
Vitamin C752.22.2
Divalproex Sodium382.22.2
Mometasone Furoate342.22.2
Sirolimus112.22.2
Desvenlafaxine Succinate222.22.2
Calcium1202.22.2
Aripiprazole992.22.2
Etonogestrel And Ethinyl Estradiol182.22.2
Calcitriol Capsules 0.25 Mcg162.22.2
Calcitriol Capsules 0.5 Mcg162.22.2
Oxybutynin Chloride72.22.2
Tizanidine192.22.2
Calcitriol162.22.2
Ramipril972.22.2
Terazosin Hydrochloride72.22.2
Estradiol Gel 0.1%352.12.1
Estradiol Transdermal352.12.1
Carvedilol1032.12.1
Methimazole62.12.1
Sertraline Hydrochloride902.12.1
Ketoprofen102.12.1
Thyroid, Porcine82.12.1
Methocarbamol172.12.1
Clopidogrel Bisulfate762.02.0
Ergocalciferol2822.02.0
Cholestyramine92.02.0
Modafinil242.02.0
Sitagliptin And Metformin Hydrochloride162.02.0
Bisoprolol Fumarate992.02.0
Nitrofurantoin122.02.0
Heparin Sodium102.02.0
Triamcinolone Acetonide Ointment Usp, 0.05%172.02.0
Benzonatate122.02.0
Niraparib162.02.0
Nitrofurantoin (Monohydrate/Macrocrystals)122.02.0
Metoprolol Succinate622.02.0
Methocarbamol Tablets122.02.0
Loratadine Tablet381.91.9
Timolol Maleate71.91.9
Doxyclycline Hyclate121.91.9
Trazodone Hydrochloride111.91.9
Metoprolol Succinate Er Tablets431.91.9
Metoprolol Tartrate1861.91.9
Alprazolam1401.91.9
Enalapril381.91.9
Ziprasidone121.91.9
Bupropion Hydrochloride671.91.9
Tafamidis81.91.9
Relugolix161.91.9
Lurasidone Hydrochloride141.81.8
Bosutinib61.81.8
Raltegravir111.81.8
Metoprolol Tartrate Injection1251.81.8
Somatropin481.81.8
Lisinopril1981.81.8
Metformin Er 500 Mg1941.81.8
Metformin Er 750 Mg1941.81.8
Everolimus331.81.8
Metoprolol1631.81.8
Lithium161.71.7
Lithium Bromatum161.71.7
Ziprasidone Mesylate91.71.7
Isosorbide Mononitrate131.71.7
Metformin2211.71.7
Crisaborole61.71.7
Ruxolitinib431.61.6
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide61.61.6
Apalutamide71.61.6
Romosozumab-Aqqg81.61.6
Tocilizumab661.61.6
Timolol71.61.6
Medroxyprogesterone Acetate281.51.5
Triamcinolone Acetonide171.51.5
Naproxen Sodium Tablet291.51.5
Cariprazine51.51.5
Clozapine671.51.5
Varenicline Tartrate421.41.4
Empagliflozin351.41.4
Ledipasvir And Sofosbuvir101.41.4
Ibuprofen Tablets, Coated221.41.4
Naproxen Sodium Tablet, Coated71.41.4
Naproxen Sodium, Coated Tablets71.41.4
Naproxen Sodium 220Mg71.41.4
Ibuprofen Sodium221.41.4
Tenofovir Disoproxil Fumarate161.31.3
Brexpiprazole81.31.3
Ranolazine51.31.3
Dofetilide51.31.3
Dalfampridine341.31.3
Naltrexone Hydrochloride And Bupropion Hydrochloride41.31.3
Conjugated Estrogens And Medroxyprogesterone Acetate111.31.3
Teriflunomide211.31.3
Oral Semaglutide341.31.3
Denosumab921.21.2
Rucaparib41.21.2
Siponimod41.21.2
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate81.21.2
Vilazodone Hydrochloride41.21.2
Paricalcitol61.21.2
Atomoxetine Hydrochloride101.21.2
Tolvaptan61.11.1
Sacubitril And Valsartan461.11.1
Brentuximab Vedotin41.11.1
Abaloparatide111.01.0
Cabotegravir31.01.0
Interferon Beta-1B71.01.0
Iohexol31.01.0
Cenobamate31.01.0
Bimatoprost101.01.0
Secukinumab550.90.9
Elexacaftor, Tezacaftor, And Ivacaftor40.90.9
Lifitegrast50.80.8
Paliperidone70.80.8
Guselkumab100.80.8
Orlistat60.60.6
Sarilumab60.60.6
Dimethyl Fumarate250.60.6
Erenumab-Aooe100.50.5
Dulaglutide160.50.5
Apremilast250.50.5
Tirzepatide270.50.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.