OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Heparin Sodium

1,090 flagged reaction(s) · 54,593 total co-reports · max PRR 12,099.2
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Benign Recurrent Intrahepatic Cholestasis 8 12,099.2 12,106.3 signal
2 Appendicolith 227 2,319.7 2,358.8 signal
3 Anti Factor V Antibody 13 2,184.6 2,186.7 signal
4 Autoimmune Heparin-induced Thrombocytopenia 30 1,972.7 1,977.0 signal
5 Sleep Disorder Therapy 84 1,270.4 1,278.3 signal
6 Antacid Therapy 54 1,256.5 1,261.4 signal
7 Heparin Resistance 44 937.3 940.3 signal
8 White Clot Syndrome 13 655.4 656.0 signal
9 Analgesic Therapy 84 580.1 583.7 signal
10 Heparin-induced Thrombocytopenia 1,273 533.2 587.8 signal
11 Drug Therapy 82 530.0 533.2 signal
12 Anticoagulant Therapy 55 379.8 381.4 signal
13 Congenital Hiatus Hernia 41 348.4 349.4 signal
14 Anti Factor X Activity Increased 10 343.7 344.0 signal
15 Malignant Melanoma Stage 0 32 329.2 330.0 signal
16 Heparin-induced Thrombocytopenia Test Positive 13 276.9 277.2 signal
17 Heparin-induced Thrombocytopenia Test 11 244.7 244.8 signal
18 Coagulation Time Shortened 36 183.3 183.8 signal
19 Bacteroides Infection 27 178.3 178.7 signal
20 Vascular Access Site Haemorrhage 16 171.6 171.8 signal
21 Platelet Aggregation Inhibition 9 166.0 166.1 signal
22 Prosthetic Cardiac Valve Thrombosis 9 148.0 148.0 signal
23 Hypoaldosteronism 21 125.5 125.7 signal
24 Congenital Multiplex Arthrogryposis 12 94.5 94.6 signal
25 Blood Phosphorus Increased 155 92.5 93.5 signal
26 Gastroduodenal Ulcer 23 89.0 89.1 signal
27 Hyperphosphataemia 116 88.8 89.5 signal
28 Coagulation Time Abnormal 16 88.6 88.7 signal
29 Bullous Haemorrhagic Dermatosis 11 86.6 86.7 signal
30 Subcapsular Renal Haematoma 10 78.8 78.8 signal
31 Graft Thrombosis 12 72.9 72.9 signal
32 Adrenal Haemorrhage 25 71.1 71.2 signal
33 Perirenal Haematoma 9 65.4 65.5 signal
34 Spinal Epidural Haematoma 23 65.1 65.2 signal
35 Activated Partial Thromboplastin Time Prolonged 202 63.5 64.4 signal
36 Bronchopulmonary Aspergillosis Allergic 35 60.8 61.0 signal
37 Operative Haemorrhage 17 59.9 60.0 signal
38 Conductive Deafness 12 59.1 59.2 signal
39 Haemorrhagic Infarction 20 57.7 57.8 signal
40 Restrictive Cardiomyopathy 11 57.2 57.2 signal
41 Infective Aneurysm 17 55.3 55.4 signal
42 Venoocclusive Disease 85 53.8 54.1 signal
43 Activated Partial Thromboplastin Time Shortened 14 52.7 52.7 signal
44 Enterococcus Test Positive 21 51.0 51.1 signal
45 Red Blood Cells Urine Positive 30 48.9 49.1 signal
46 Total Lung Capacity Decreased 49 48.4 48.5 signal
47 Cerebral Venous Sinus Thrombosis 25 48.2 48.3 signal
48 Extradural Haematoma 40 47.6 47.7 signal
49 Haematoma Muscle 35 47.0 47.1 signal
50 Retroperitoneal Haematoma 64 46.0 46.2 signal
51 Hepatic Infarction 11 46.0 46.0 signal
52 Renal Vein Thrombosis 19 45.1 45.2 signal
53 Coagulation Time Prolonged 44 44.5 44.7 signal
54 Thrombectomy 9 43.3 43.4 signal
55 Vascular Stent Thrombosis 55 42.6 42.8 signal
56 Product Measured Potency Issue 27 42.1 42.1 signal
57 Incision Site Pain 31 41.5 41.6 signal
58 Volume Blood Decreased 11 40.9 40.9 signal
59 Appendicitis 237 40.1 40.8 signal
60 Retroperitoneal Haemorrhage 62 39.4 39.6 signal
61 Fungal Sepsis 21 39.4 39.5 signal
62 Aortic Thrombosis 29 39.3 39.3 signal
63 Vascular Graft Occlusion 9 37.7 37.7 signal
64 Thrombosis In Device 76 36.0 36.2 signal
65 Iron Deficiency 99 34.9 35.1 signal
66 Ventricular Fibrillation 245 34.5 35.1 signal
67 Epidermolysis 10 34.2 34.2 signal
68 Alpha Haemolytic Streptococcal Infection 20 33.7 33.7 signal
69 Arterial Thrombosis Limb 9 33.5 33.5 signal
70 Cardiogenic Shock 299 32.8 33.5 signal
71 Haemothorax 60 32.3 32.5 signal
72 Dry Gangrene 13 32.1 32.2 signal
73 Device Related Thrombosis 20 31.9 32.0 signal
74 Blood Uric Acid Increased 117 31.7 32.0 signal
75 Increased Viscosity Of Upper Respiratory Secretion 15 31.1 31.2 signal
76 Shock Haemorrhagic 161 31.0 31.3 signal
77 Hand Dermatitis 13 30.8 30.8 signal
78 Coagulation Test Abnormal 15 30.8 30.8 signal
79 Lung Opacity 50 30.4 30.5 signal
80 Haemoperitoneum 15 29.8 29.9 signal
81 Peripheral Artery Thrombosis 26 28.8 28.8 signal
82 Hypophosphataemia 134 28.5 28.8 signal
83 Cardiac Procedure Complication 11 28.1 28.1 signal
84 Myasthenia Gravis 139 27.5 27.8 signal
85 Transmission Of An Infectious Agent Via A Medicinal Product 15 27.2 27.3 signal
86 Coronary Artery Thrombosis 35 27.0 27.0 signal
87 Abdominal Wall Haematoma 33 26.4 26.5 signal
88 Pulmonary Artery Thrombosis 13 26.2 26.3 signal
89 Cardiac Ventricular Thrombosis 21 25.9 25.9 signal
90 Peripheral Ischaemia 68 25.9 26.0 signal
91 Arterial Thrombosis 32 25.7 25.7 signal
92 Cerebral Haematoma 54 25.1 25.2 signal
93 Cerebellar Haemorrhage 23 25.0 25.1 signal
94 Vascular Pseudoaneurysm 28 25.0 25.0 signal
95 Haemorrhagic Cerebral Infarction 11 24.3 24.3 signal
96 Puncture Site Haemorrhage 11 24.3 24.3 signal
97 Delayed Graft Function 11 24.2 24.2 signal
98 Anticoagulation Drug Level Above Therapeutic 24 24.2 24.3 signal
99 Anticoagulation Drug Level Below Therapeutic 12 24.2 24.2 signal
100 Pericardial Haemorrhage 34 24.2 24.2 signal
101 Jugular Vein Thrombosis 26 22.9 23.0 signal
102 Catheter Site Haemorrhage 36 22.8 22.8 signal
103 Cerebral Palsy 14 22.7 22.8 signal
104 Heart Transplant 13 22.5 22.5 signal
105 Abdominal Compartment Syndrome 9 22.5 22.5 signal
106 Intestinal Infarction 13 22.1 22.2 signal
107 Arterial Haemorrhage 16 21.6 21.7 signal
108 Intra-abdominal Haemorrhage 33 21.5 21.5 signal
109 Aortic Stenosis 48 21.4 21.5 signal
110 Suspected Transmission Of An Infectious Agent Via Product 17 21.4 21.4 signal
111 Superior Sagittal Sinus Thrombosis 11 21.1 21.2 signal
112 Hypercoagulation 26 21.1 21.1 signal
113 Spontaneous Haematoma 10 20.9 20.9 signal
114 Embolism Arterial 16 20.7 20.7 signal
115 Multiple Organ Dysfunction Syndrome 365 20.3 20.8 signal
116 Renal Infarct 19 20.3 20.3 signal
117 Pharyngeal Haemorrhage 16 20.1 20.1 signal
118 Pleuritic Pain 35 19.6 19.6 signal
119 Vena Cava Thrombosis 21 19.6 19.6 signal
120 Electromechanical Dissociation 10 19.1 19.2 signal
121 Compartment Syndrome 32 19.0 19.1 signal
122 Therapeutic Product Effect Increased 14 19.0 19.1 signal
123 Serratia Infection 9 18.9 18.9 signal
124 Muscle Haemorrhage 47 18.2 18.2 signal
125 Urinary Tract Infection Enterococcal 11 18.1 18.1 signal
126 Intraventricular Haemorrhage 29 18.0 18.1 signal
127 Intracardiac Thrombus 36 17.9 18.0 signal
128 Cardiac Tamponade 55 17.9 18.0 signal
129 Subclavian Vein Thrombosis 13 17.6 17.6 signal
130 Blood Fibrinogen Increased 9 17.5 17.5 signal
131 Intra-abdominal Haematoma 14 17.5 17.5 signal
132 Joint Contracture 12 17.3 17.3 signal
133 Brain Herniation 33 17.1 17.2 signal
134 Incision Site Haemorrhage 9 17.1 17.1 signal
135 Sinus Arrest 17 17.0 17.1 signal
136 Splenic Infarction 19 17.0 17.0 signal
137 Chronic Spontaneous Urticaria 12 16.9 16.9 signal
138 Troponin Increased 82 16.8 16.9 signal
139 Device Related Sepsis 22 16.8 16.8 signal
140 Peritoneal Haemorrhage 15 16.5 16.5 signal
141 Procedural Hypotension 9 16.3 16.3 signal
142 Product Packaging Confusion 25 15.9 15.9 signal
143 Atrial Thrombosis 21 15.6 15.7 signal
144 Cerebral Artery Embolism 12 15.2 15.2 signal
145 Catheter Related Complication 11 14.9 14.9 signal
146 Respiratory Symptom 27 14.9 14.9 signal
147 Enterococcal Bacteraemia 10 14.7 14.7 signal
148 Blood Loss Anaemia 21 14.6 14.6 signal
149 Skin Necrosis 49 14.6 14.6 signal
150 Gangrene 57 14.5 14.6 signal
151 Venous Thrombosis 37 14.5 14.6 signal
152 Ascites 275 14.5 14.7 signal
153 Disseminated Intravascular Coagulation 132 14.5 14.6 signal
154 Mixed Liver Injury 27 14.3 14.4 signal
155 Splenic Rupture 15 14.1 14.1 signal
156 Bleeding Time Prolonged 11 14.0 14.0 signal
157 Complications Of Transplanted Kidney 20 13.9 13.9 signal
158 Aplastic Anaemia 47 13.9 13.9 signal
159 Clostridium Test Positive 19 13.5 13.5 signal
160 Renal Artery Stenosis 12 13.4 13.4 signal
161 Toxic Epidermal Necrolysis 130 13.3 13.4 signal
162 Device Infusion Issue 21 13.3 13.3 signal
163 Brain Death 26 12.9 13.0 signal
164 Streptococcal Bacteraemia 9 12.9 12.9 signal
165 Chronic Kidney Disease-mineral And Bone Disorder 9 12.9 12.9 signal
166 Haemorrhage Intracranial 124 12.8 12.9 signal
167 Benign Prostatic Hyperplasia 42 12.5 12.6 signal
168 Peripheral Artery Occlusion 11 12.1 12.2 signal
169 Antibody Test Positive 13 12.0 12.0 signal
170 Incorrect Route Of Product Administration 129 11.9 12.0 signal
171 Post Procedural Haematoma 13 11.8 11.8 signal
172 Streptococcal Sepsis 9 11.6 11.7 signal
173 Blood Calcium Increased 66 11.6 11.7 signal
174 Hyperparathyroidism Secondary 19 11.6 11.6 signal
175 Haemodynamic Instability 56 11.5 11.6 signal
176 Coagulopathy 124 11.5 11.6 signal
177 Breast Disorder 15 11.3 11.3 signal
178 Bacterial Infection 135 11.2 11.3 signal
179 Hyperlactacidaemia 19 11.1 11.1 signal
180 Multi-organ Failure 126 11.1 11.2 signal
181 Venous Thrombosis Limb 15 11.1 11.1 signal
182 Breath Sounds Abnormal 35 11.0 11.0 signal
183 Hyperlipidaemia 85 10.9 11.0 signal
184 Nephrogenic Anaemia 33 10.9 10.9 signal
185 Platelet Transfusion 9 10.9 10.9 signal
186 Upper Gastrointestinal Haemorrhage 118 10.8 10.9 signal
187 Pulse Absent 33 10.7 10.7 signal
188 Bilirubin Conjugated Increased 16 10.6 10.6 signal
189 Subarachnoid Haemorrhage 70 10.6 10.6 signal
190 Extremity Necrosis 12 10.5 10.6 signal
191 Cytomegalovirus Test Positive 12 10.5 10.5 signal
192 Leg Amputation 28 10.4 10.5 signal
193 Ischaemic Hepatitis 9 10.3 10.3 signal
194 Diplegia 13 10.1 10.1 signal
195 Drug Effect Less Than Expected 91 10.0 10.0 signal
196 Protein Urine Present 32 9.9 10.0 signal
197 Spinal Cord Compression 25 9.9 9.9 signal
198 Renal Haemorrhage 13 9.8 9.8 signal
199 Platelet Disorder 16 9.7 9.8 signal
200 Pulmonary Infarction 15 9.7 9.7 signal
201 Pulmonary Haemorrhage 49 9.7 9.7 signal
202 Pulmonary Alveolar Haemorrhage 35 9.6 9.7 signal
203 Pelvic Venous Thrombosis 9 9.6 9.6 signal
204 Blood Test Abnormal 87 9.6 9.6 signal
205 Cardiovascular Insufficiency 10 9.5 9.5 signal
206 Hepatic Cytolysis 75 9.5 9.5 signal
207 Stomach Discomfort 32 9.4 9.4 signal
208 Post Procedural Haemorrhage 71 9.4 9.4 signal
209 Spinal Cord Disorder 10 9.3 9.3 signal
210 Neutrophil Count Increased 62 9.3 9.3 signal
211 Electrocardiogram St Segment Elevation 20 9.3 9.3 signal
212 Haemorrhagic Transformation Stroke 9 9.2 9.2 signal
213 Hypoproteinaemia 11 9.2 9.2 signal
214 End Stage Renal Disease 108 9.0 9.1 signal
215 Transfusion 61 8.9 9.0 signal
216 Rash Morbilliform 16 8.9 8.9 signal
217 Fungaemia 9 8.9 8.9 signal
218 Cerebral Haemorrhage 205 8.8 9.0 signal
219 Haematoma 149 8.8 8.9 signal
220 Lymphocyte Count Decreased 101 8.8 8.9 signal
221 Embolic Stroke 20 8.8 8.8 signal
222 Hypovolaemic Shock 27 8.7 8.8 signal
223 Haemorrhage Subcutaneous 20 8.7 8.7 signal
224 Anaphylactoid Reaction 23 8.7 8.7 signal
225 Eosinophilia 98 8.6 8.7 signal
226 Electric Shock Sensation 15 8.6 8.6 signal
227 Hyponatraemia 313 8.6 8.8 signal
228 Cerebral Infarction 136 8.6 8.6 signal
229 Cerebral Venous Thrombosis 10 8.4 8.5 signal
230 Intestinal Ischaemia 30 8.4 8.5 signal
231 Thrombosis 437 8.3 8.6 signal
232 Product Contamination 19 8.3 8.4 signal
233 Resuscitation 9 8.3 8.3 signal
234 Hyperuricaemia 22 8.3 8.3 signal
235 Acute Generalised Exanthematous Pustulosis 41 8.2 8.2 signal
236 Subdural Haematoma 76 8.2 8.2 signal
237 Blood Culture Positive 16 8.1 8.1 signal
238 Neuralgia 128 8.1 8.2 signal
239 Bacteraemia 62 8.1 8.1 signal
240 Cytomegalovirus Viraemia 23 8.1 8.1 signal
241 Pulmonary Embolism 500 8.1 8.3 signal
242 Hypoalbuminaemia 40 8.1 8.1 signal
243 Duodenal Ulcer Haemorrhage 15 8.0 8.0 signal
244 Incorrect Drug Administration Rate 22 8.0 8.0 signal
245 Aspiration 56 8.0 8.0 signal
246 Procedural Haemorrhage 20 7.9 7.9 signal
247 Venoocclusive Liver Disease 25 7.8 7.8 signal
248 Procedural Complication 39 7.8 7.8 signal
249 Cell Death 10 7.7 7.8 signal
250 Poor Quality Drug Administered 33 7.7 7.8 signal
251 Ulcer 80 7.7 7.8 signal
252 Pseudomembranous Colitis 11 7.5 7.6 signal
253 Bladder Spasm 9 7.5 7.5 signal
254 Oliguria 30 7.4 7.5 signal
255 Blood Urea Increased 81 7.4 7.4 signal
256 Prothrombin Time Prolonged 29 7.4 7.4 signal
257 Pulseless Electrical Activity 20 7.4 7.4 signal
258 Type Iv Hypersensitivity Reaction 13 7.3 7.4 signal
259 Ischaemia 22 7.3 7.3 signal
260 Vascular Occlusion 10 7.3 7.3 signal
261 Hepatitis Fulminant 14 7.3 7.3 signal
262 Deep Vein Thrombosis 303 7.1 7.3 signal
263 Therapeutic Product Effect Decreased 205 7.1 7.2 signal
264 Embolism Venous 14 7.1 7.1 signal
265 Thrombophlebitis 16 7.0 7.0 signal
266 Transplant Failure 11 6.9 6.9 signal
267 Paraplegia 13 6.9 6.9 signal
268 Gastrointestinal Necrosis 13 6.9 6.9 signal
269 Lower Gastrointestinal Haemorrhage 33 6.8 6.9 signal
270 Organ Failure 18 6.8 6.8 signal
271 Hypernatraemia 22 6.8 6.8 signal
272 Cerebral Ischaemia 23 6.8 6.8 signal
273 Low Birth Weight Baby 35 6.8 6.8 signal
274 Sepsis 490 6.8 7.0 signal
275 Osteolysis 9 6.8 6.8 signal
276 Renal Failure Chronic 34 6.7 6.7 signal
277 Subdural Haemorrhage 12 6.7 6.7 signal
278 Unresponsive To Stimuli 111 6.6 6.7 signal
279 Embolism 36 6.6 6.6 signal
280 Blood Albumin Decreased 34 6.6 6.6 signal
281 Gout 77 6.6 6.6 signal
282 Rash Maculo-papular 94 6.5 6.6 signal
283 Stress 305 6.5 6.7 signal
284 Duodenitis 13 6.5 6.5 signal
285 Otitis Media 14 6.5 6.5 signal
286 Thrombocytopenia 471 6.5 6.7 signal
287 Blood Pressure Systolic Decreased 19 6.5 6.5 signal
288 Adrenal Disorder 8 6.4 6.4 signal
289 Labelled Drug-drug Interaction Medication Error 37 6.4 6.4 signal
290 Ischaemic Stroke 74 6.4 6.4 signal
291 Enterococcal Infection 20 6.4 6.4 signal
292 Hyperkalaemia 144 6.3 6.4 signal
293 Ventricular Arrhythmia 15 6.3 6.3 signal
294 Mouth Haemorrhage 30 6.3 6.3 signal
295 Toxic Encephalopathy 20 6.2 6.2 signal
296 Klebsiella Infection 20 6.1 6.1 signal
297 Diverticulum Intestinal Haemorrhagic 9 6.1 6.1 signal
298 Rales 23 6.1 6.1 signal
299 Systemic Inflammatory Response Syndrome 15 6.1 6.1 signal
300 Fibrin D Dimer Increased 14 6.0 6.1 signal
301 Haemorrhagic Diathesis 14 6.0 6.0 signal
302 Chest X-ray Abnormal 12 6.0 6.0 signal
303 Talipes 12 5.9 5.9 signal
304 Staphylococcal Sepsis 19 5.9 5.9 signal
305 Carotid Artery Occlusion 14 5.9 5.9 signal
306 Hypoxic-ischaemic Encephalopathy 10 5.9 5.9 signal
307 Acute Myocardial Infarction 112 5.8 5.9 signal
308 Leukocytosis 68 5.8 5.8 signal
309 Kidney Transplant Rejection 18 5.7 5.7 signal
310 Portal Vein Thrombosis 12 5.7 5.7 signal
311 Diabetes Insipidus 9 5.7 5.7 signal
312 Febrile Neutropenia 246 5.7 5.8 signal
313 Recurrent Cancer 15 5.7 5.7 signal
314 Systemic Candida 9 5.6 5.6 signal
315 Oedema Mouth 12 5.6 5.6 signal
316 Cerebrovascular Disorder 11 5.6 5.6 signal
317 High Density Lipoprotein Decreased 12 5.5 5.5 signal
318 Coronary Artery Stenosis 18 5.5 5.5 signal
319 Premature Delivery 57 5.5 5.5 signal
320 Pseudomonas Infection 30 5.5 5.5 signal
321 Blood Pressure Decreased 234 5.4 5.5 signal
322 Cancer Pain 9 5.4 5.4 signal
323 Hydrocephalus 19 5.4 5.4 signal
324 Ecchymosis 24 5.4 5.4 signal
325 Haemoglobin Decreased 354 5.3 5.4 signal
326 Full Blood Count Abnormal 36 5.3 5.3 signal
327 Stevens-johnson Syndrome 76 5.2 5.3 signal
328 Atelectasis 33 5.2 5.2 signal
329 Septic Shock 147 5.2 5.3 signal
330 Purpura 30 5.2 5.2 signal
331 Drug Reaction With Eosinophilia And Systemic Symptoms 86 5.2 5.2 signal
332 Angiopathy 19 5.2 5.2 signal
333 Micturition Urgency 38 5.2 5.2 signal
334 Tumour Marker Increased 16 5.1 5.1 signal
335 Poor Peripheral Circulation 14 5.0 5.0 signal
336 Patent Ductus Arteriosus 13 5.0 5.0 signal
337 Haemorrhage 340 5.0 5.1 signal
338 Brain Natriuretic Peptide Increased 10 5.0 5.0 signal
339 Hypercholesterolaemia 31 5.0 5.0 signal
340 Drug Hypersensitivity 628 5.0 5.2 signal
341 Endotracheal Intubation 9 4.9 5.0 signal
342 Premature Baby 97 4.9 5.0 signal
343 Monoplegia 14 4.9 4.9 signal
344 Clostridium Difficile Colitis 34 4.9 4.9 signal
345 Dermatitis Exfoliative Generalised 11 4.9 4.9 signal
346 Dermatitis Bullous 23 4.9 4.9 signal
347 Wound Complication 11 4.9 4.9 signal
348 Haemorrhagic Stroke 25 4.9 4.9 signal
349 Escherichia Infection 26 4.9 4.9 signal
350 Faeces Soft 23 4.9 4.9 signal
351 Respiratory Rate Decreased 10 4.9 4.9 signal
352 Vulvovaginal Pain 15 4.8 4.8 signal
353 Carotid Artery Stenosis 11 4.8 4.8 signal
354 Blood Magnesium Decreased 27 4.8 4.8 signal
355 Hypervolaemia 15 4.8 4.8 signal
356 Duodenal Ulcer 22 4.8 4.8 signal
357 Hypovolaemia 18 4.7 4.7 signal
358 Pneumonia Bacterial 28 4.7 4.7 signal
359 Haematuria 105 4.7 4.7 signal
360 Haemoptysis 85 4.7 4.7 signal
361 Melaena 67 4.7 4.7 signal
362 Acute Pulmonary Oedema 17 4.7 4.7 signal
363 Shock 69 4.6 4.7 signal
364 Hypoxia 106 4.6 4.7 signal
365 Metabolic Encephalopathy 9 4.6 4.6 signal
366 Acute Respiratory Distress Syndrome 53 4.6 4.6 signal
367 Petechiae 31 4.6 4.6 signal
368 Cytolytic Hepatitis 10 4.6 4.6 signal
369 General Physical Health Deterioration 339 4.5 4.6 signal
370 Catheter Site Infection 11 4.5 4.5 signal
371 Ileus Paralytic 13 4.5 4.5 signal
372 Thrombophlebitis Superficial 9 4.5 4.5 signal
373 Protein Total Decreased 11 4.5 4.5 signal
374 Portal Hypertension 9 4.5 4.5 signal
375 Acute Graft Versus Host Disease In Skin 8 4.5 4.5 signal
376 Foetal Death 15 4.4 4.5 signal
377 Platelet Count Decreased 307 4.4 4.5 signal
378 Aortic Dissection 12 4.4 4.4 signal
379 Blood Blister 9 4.4 4.4 signal
380 Necrosis 16 4.4 4.4 signal
381 Post Procedural Complication 55 4.4 4.4 signal
382 Chronic Obstructive Pulmonary Disease 149 4.4 4.4 signal
383 Myoclonus 34 4.4 4.4 signal
384 Blood Lactate Dehydrogenase Increased 45 4.3 4.3 signal
385 Blood Creatinine Increased 184 4.3 4.4 signal
386 Cardiopulmonary Failure 11 4.3 4.3 signal
387 Blood Cholesterol Increased 131 4.3 4.3 signal
388 Hypotension 562 4.3 4.5 signal
389 Transaminases Increased 62 4.3 4.3 signal
390 Abdominal Distension 290 4.3 4.4 signal
391 Thrombotic Microangiopathy 27 4.3 4.3 signal
392 Encephalopathy 68 4.3 4.3 signal
393 Brain Oedema 35 4.3 4.3 signal
394 Cardiac Arrest 229 4.2 4.3 signal
395 Pleural Effusion 168 4.2 4.3 signal
396 Adrenal Insufficiency 33 4.2 4.2 signal
397 Endocarditis 14 4.2 4.2 signal
398 Device Related Infection 42 4.2 4.2 signal
399 Haemolysis 21 4.2 4.2 signal
400 Peptic Ulcer 9 4.2 4.2 signal
401 Blood Creatine Increased 12 4.2 4.2 signal
402 Peripheral Arterial Occlusive Disease 11 4.1 4.1 signal
403 Cytopenia 32 4.1 4.1 signal
404 Hepatic Function Abnormal 99 4.1 4.1 signal
405 Cholestasis 51 4.1 4.1 signal
406 Iron Deficiency Anaemia 24 4.0 4.0 signal
407 Bronchopneumonia 9 4.0 4.0 signal
408 Haemodialysis 22 4.0 4.0 signal
409 Bronchopulmonary Aspergillosis 20 4.0 4.0 signal
410 Cardiac Failure Chronic 11 4.0 4.0 signal
411 Pericardial Effusion 59 3.9 4.0 signal
412 Cardiac Failure Acute 17 3.9 3.9 signal
413 Arteriospasm Coronary 10 3.9 3.9 signal
414 Oesophageal Candidiasis 10 3.9 3.9 signal
415 Intracranial Pressure Increased 14 3.9 3.9 signal
416 Anaemia 479 3.9 4.0 signal
417 Obstruction 10 3.8 3.8 signal
418 Liver Function Test Increased 53 3.8 3.8 signal
419 Ventricular Tachycardia 41 3.8 3.8 signal
420 Chronic Graft Versus Host Disease 9 3.8 3.8 signal
421 Stillbirth 12 3.8 3.8 signal
422 Renal Injury 74 3.8 3.8 signal
423 Coronary Artery Disease 75 3.8 3.8 signal
424 International Normalised Ratio Decreased 10 3.8 3.8 signal
425 Tachypnoea 33 3.7 3.7 signal
426 Blood Pressure Diastolic Decreased 18 3.7 3.7 signal
427 Right Ventricular Failure 17 3.7 3.7 signal
428 Tumour Lysis Syndrome 21 3.7 3.7 signal
429 Live Birth 20 3.7 3.7 signal
430 Hypertriglyceridaemia 14 3.7 3.7 signal
431 Atrioventricular Block Complete 16 3.7 3.7 signal
432 Aspartate Aminotransferase Increased 127 3.7 3.7 signal
433 Respiratory Failure 174 3.7 3.7 signal
434 Acute Graft Versus Host Disease 11 3.7 3.7 signal
435 Anaphylactic Shock 61 3.7 3.7 signal
436 Dermatitis Exfoliative 12 3.6 3.6 signal
437 Renal Failure Acute 102 3.6 3.7 signal
438 Haematocrit Decreased 47 3.6 3.6 signal
439 Escherichia Urinary Tract Infection 10 3.6 3.6 signal
440 Cardio-respiratory Arrest 99 3.6 3.6 signal
441 Hemiparesis 40 3.6 3.6 signal
442 Streptococcal Infection 13 3.6 3.6 signal
443 Decubitus Ulcer 19 3.6 3.6 signal
444 Gastric Ulcer Haemorrhage 13 3.6 3.6 signal
445 Haematemesis 59 3.6 3.6 signal
446 Hyperaesthesia 19 3.5 3.5 signal
447 Therapeutic Product Ineffective 9 3.5 3.5 signal
448 Respiratory Acidosis 9 3.5 3.5 signal
449 Urine Output Decreased 20 3.5 3.5 signal
450 Premature Labour 13 3.5 3.5 signal
451 Mucosal Inflammation 59 3.5 3.5 signal
452 Bronchiectasis 15 3.5 3.5 signal
453 Coronary Artery Occlusion 31 3.5 3.5 signal
454 Azotaemia 9 3.4 3.4 signal
455 Haemoglobin Increased 10 3.4 3.4 signal
456 Respiratory Distress 61 3.4 3.4 signal
457 Seasonal Allergy 31 3.4 3.4 signal
458 Drug Level Below Therapeutic 12 3.4 3.4 signal
459 Attention Deficit Hyperactivity Disorder 9 3.3 3.3 signal
460 Circulatory Collapse 37 3.3 3.3 signal
461 Heart Rate Abnormal 12 3.3 3.3 signal
462 Renal Failure 289 3.3 3.4 signal
463 Hemiplegia 18 3.3 3.3 signal
464 Pulmonary Hypertension 45 3.3 3.3 signal
465 Dry Mouth 174 3.3 3.3 signal
466 Gingival Pain 17 3.3 3.3 signal
467 Drug Exposure During Pregnancy 73 3.2 3.3 signal
468 Gastric Ulcer 40 3.2 3.2 signal
469 Acidosis 16 3.2 3.2 signal
470 Infusion Site Extravasation 13 3.2 3.2 signal
471 Pneumothorax 33 3.2 3.2 signal
472 Anuria 18 3.2 3.2 signal
473 White Blood Cell Count Increased 80 3.2 3.2 signal
474 Diabetes Mellitus 159 3.2 3.2 signal
475 Staphylococcal Bacteraemia 9 3.2 3.2 signal
476 Hypokalaemia 95 3.2 3.2 signal
477 Obstructive Airways Disorder 23 3.2 3.2 signal
478 Abdominal Pain 478 3.2 3.2 signal
479 International Normalised Ratio Increased 59 3.1 3.2 signal
480 Blood Iron Decreased 24 3.1 3.1 signal
481 Renal Tubular Necrosis 20 3.1 3.1 signal
482 Ileus 25 3.1 3.1 signal
483 Cardiomyopathy 30 3.1 3.1 signal
484 Haemorrhagic Anaemia 9 3.1 3.1 signal
485 Hepatic Failure 60 3.0 3.1 signal
486 Acute Respiratory Failure 38 3.0 3.1 signal
487 Malnutrition 22 3.0 3.0 signal
488 Peritonitis 41 3.0 3.0 signal
489 Toxic Skin Eruption 20 3.0 3.0 signal
490 Pharmaceutical Product Complaint 52 3.0 3.0 signal
491 Gastrointestinal Haemorrhage 166 3.0 3.1 signal
492 Swelling 184 3.0 3.1 signal
493 Cyanosis 31 3.0 3.0 signal
494 Hypocalcaemia 37 3.0 3.0 signal
495 Left Ventricular Dysfunction 13 3.0 3.0 signal
496 Erythema Multiforme 18 3.0 3.0 signal
497 Myocardial Ischaemia 22 2.9 2.9 signal
498 Product Label Confusion 11 2.9 2.9 signal
499 Sleep Disorder 132 2.9 2.9 signal
500 Fear 51 2.9 2.9 signal
501 Dry Throat 19 2.9 2.9 signal
502 C-reactive Protein Increased 68 2.9 2.9 signal
503 Candida Infection 31 2.9 2.9 signal
504 Anhedonia 49 2.8 2.8 signal
505 Lower Respiratory Tract Infection 83 2.8 2.8 signal
506 Epistaxis 137 2.8 2.8 signal
507 Acute Coronary Syndrome 15 2.8 2.8 signal
508 Device Occlusion 25 2.8 2.8 signal
509 Torsade De Pointes 14 2.7 2.7 signal
510 Pancytopenia 99 2.7 2.7 signal
511 Arterial Occlusive Disease 14 2.7 2.7 signal
512 Constipation 383 2.7 2.8 signal
513 Mitral Valve Incompetence 20 2.7 2.7 signal
514 General Physical Condition Abnormal 12 2.7 2.7 signal
515 Toe Amputation 9 2.7 2.7 signal
516 Exercise Tolerance Decreased 10 2.7 2.7 signal
517 Paraesthesia Oral 25 2.7 2.7 signal
518 Pharyngeal Oedema 27 2.7 2.7 signal
519 Ventricular Extrasystoles 18 2.7 2.7 signal
520 Acute Kidney Injury 263 2.7 2.7 signal
521 Hyperthermia 13 2.6 2.6 signal
522 Liver Disorder 76 2.6 2.6 signal
523 Gamma-glutamyltransferase Increased 38 2.6 2.6 signal
524 Joint Dislocation 18 2.6 2.6 signal
525 Renal Impairment 143 2.6 2.6 signal
526 Pneumonia Aspiration 42 2.6 2.6 signal
527 Transient Ischaemic Attack 57 2.6 2.6 signal
528 Hepatitis 43 2.6 2.6 signal
529 Angina Unstable 11 2.6 2.6 signal
530 Dermatitis Contact 19 2.6 2.6 signal
531 Alanine Aminotransferase Increased 102 2.5 2.6 signal
532 Graft Versus Host Disease 12 2.5 2.5 signal
533 Cardiac Failure 133 2.5 2.6 signal
534 Hyperbilirubinaemia 17 2.5 2.5 signal
535 Metabolic Acidosis 52 2.5 2.5 signal
536 Myocardial Infarction 287 2.5 2.5 signal
537 Thirst 29 2.5 2.5 signal
538 Atrial Flutter 13 2.5 2.5 signal
539 Dialysis 23 2.5 2.5 signal
540 Blood Creatine Phosphokinase Increased 47 2.5 2.5 signal
541 Ejection Fraction Decreased 25 2.5 2.5 signal
542 Anaphylactic Reaction 88 2.5 2.5 signal
543 Immune Effector Cell-associated Neurotoxicity Syndrome 9 2.5 2.5 signal
544 Staphylococcal Infection 53 2.5 2.5 signal
545 Hypotonia 16 2.4 2.5 signal
546 Joint Injury 34 2.4 2.4 signal
547 Complication Associated With Device 21 2.4 2.4 signal
548 Blood Bilirubin Increased 43 2.4 2.4 signal
549 Pulmonary Congestion 21 2.4 2.4 signal
550 Spinal Osteoarthritis 14 2.4 2.4 signal
551 Upper Respiratory Tract Infection 73 2.4 2.4 signal
552 Bradycardia 84 2.4 2.4 signal
553 Atrial Fibrillation 154 2.4 2.4 signal
554 Agranulocytosis 29 2.4 2.4 signal
555 Pulmonary Toxicity 11 2.4 2.4 signal
556 Sinus Tachycardia 22 2.4 2.4 signal
557 Poor Venous Access 16 2.4 2.4 signal
558 Pulmonary Mass 23 2.4 2.4 signal
559 Therapeutic Response Decreased 93 2.4 2.4 signal
560 Oral Candidiasis 20 2.4 2.4 signal
561 Apnoea 12 2.4 2.4 signal
562 Intentional Product Misuse 133 2.4 2.4 signal
563 Paralysis 22 2.3 2.4 signal
564 Hereditary Angioedema 16 2.3 2.3 signal
565 Oxygen Saturation Decreased 85 2.3 2.3 signal
566 Tachycardia 135 2.3 2.3 signal
567 Bone Marrow Failure 31 2.3 2.3 signal
568 Cholecystitis 18 2.3 2.3 signal
569 Covid-19 Pneumonia 18 2.3 2.3 signal
570 Arteriosclerosis Coronary Artery 10 2.3 2.3 signal
571 Wrong Product Administered 10 2.3 2.3 signal
572 Rash Pustular 11 2.3 2.3 signal
573 Transplant Rejection 12 2.3 2.3 signal
574 Hyperglycaemia 54 2.3 2.3 signal
575 Neutrophil Count Decreased 60 2.3 2.3 signal
576 Sputum Discoloured 14 2.3 2.3 signal
577 Drug Intolerance 142 2.3 2.3 signal
578 Hydronephrosis 11 2.3 2.3 signal
579 Generalised Tonic-clonic Seizure 24 2.3 2.3 signal
580 Supraventricular Tachycardia 14 2.2 2.2 signal
581 Generalised Oedema 18 2.2 2.2 signal
582 Infusion Site Swelling 9 2.2 2.2 signal
583 Cholangitis 9 2.2 2.2 signal
584 Oedema Peripheral 178 2.2 2.2 signal
585 Cardiomegaly 18 2.2 2.2 signal
586 Pulmonary Oedema 65 2.2 2.2 signal
587 Lymphoedema 10 2.2 2.2 signal
588 Joint Effusion 10 2.2 2.2 signal
589 Large Intestine Polyp 10 2.2 2.2 signal
590 Maternal Exposure During Pregnancy 127 2.2 2.2 signal
591 Weight Fluctuation 15 2.2 2.2 signal
592 Drug-induced Liver Injury 44 2.2 2.2 signal
593 Pyrexia 485 2.2 2.2 signal
594 Foetal Exposure During Pregnancy 113 2.1 2.1 signal
595 Interstitial Lung Disease 67 2.1 2.1 signal
596 Cytomegalovirus Infection 23 2.1 2.1 signal
597 Arteriosclerosis 13 2.1 2.1 signal
598 Condition Aggravated 413 2.1 2.1 signal
599 Liver Injury 33 2.1 2.1 signal
600 Drug Eruption 24 2.1 2.1 signal
601 Post Procedural Infection 11 2.1 2.1 signal
602 Skin Mass 9 2.1 2.1 signal
603 Anal Incontinence 12 2.1 2.1 signal
604 Infusion Site Pain 17 2.0 2.0 signal
605 Cardiovascular Disorder 34 2.0 2.0 signal
606 Status Epilepticus 15 2.0 2.0 signal
607 Eosinophil Count Increased 11 2.0 2.0 signal
608 Retching 28 2.0 2.0 signal
609 Gingival Bleeding 18 2.0 2.0 signal
610 Medication Error 73 2.0 2.0 signal
611 Nervous System Disorder 41 2.0 2.0 signal
612 Small Intestinal Obstruction 16 2.0 2.0 signal
613 Heart Rate Decreased 46 2.0 2.0 signal
614 Vomiting 610 2.0 2.0 no signal
615 Low Density Lipoprotein Increased 10 2.0 2.0 no signal
616 Hypomagnesaemia 18 2.0 2.0 no signal
617 Large Intestine Perforation 9 2.0 2.0 no signal
618 Extrasystoles 9 2.0 2.0 no signal
619 Flank Pain 12 2.0 2.0 no signal
620 Carpal Tunnel Syndrome 18 2.0 2.0 no signal
621 Grand Mal Convulsion 12 2.0 2.0 no signal
622 Body Temperature Increased 26 1.9 2.0 no signal
623 Lung Infection 20 1.9 1.9 no signal
624 Lung Disorder 62 1.9 1.9 no signal
625 Contraindicated Product Administered 38 1.9 1.9 no signal
626 Sneezing 28 1.9 1.9 no signal
627 Blood Alkaline Phosphatase Increased 31 1.9 1.9 no signal
628 Depressed Level Of Consciousness 49 1.9 1.9 no signal
629 Blood Calcium Decreased 14 1.9 1.9 no signal
630 Exposure During Pregnancy 77 1.9 1.9 no signal
631 Lung Infiltration 11 1.9 1.9 no signal
632 Gastrointestinal Infection 11 1.9 1.9 no signal
633 Liver Function Test Abnormal 36 1.9 1.9 no signal
634 Incontinence 13 1.9 1.9 no signal
635 Haemolytic Anaemia 11 1.9 1.9 no signal
636 Mental Status Changes 34 1.9 1.9 no signal
637 Internal Haemorrhage 14 1.9 1.9 no signal
638 Leukopenia 61 1.9 1.9 no signal
639 Gastritis 32 1.9 1.9 no signal
640 Electrolyte Imbalance 14 1.9 1.9 no signal
641 Hypercalcaemia 15 1.9 1.9 no signal
642 Vasculitis 14 1.8 1.8 no signal
643 Hypoaesthesia Oral 18 1.8 1.8 no signal
644 Urosepsis 11 1.8 1.8 no signal
645 Peritonitis Bacterial 12 1.8 1.8 no signal
646 Aphasia 36 1.8 1.8 no signal
647 Jaundice 32 1.8 1.8 no signal
648 Chest Pain 220 1.8 1.8 no signal
649 Blood Triglycerides Increased 21 1.8 1.8 no signal
650 Rash Generalised 31 1.8 1.8 no signal
651 Rhabdomyolysis 49 1.8 1.8 no signal
652 Tubulointerstitial Nephritis 22 1.8 1.8 no signal
653 Drug Interaction 186 1.8 1.8 no signal
654 Cellulitis 59 1.8 1.8 no signal
655 Pancreatitis Acute 26 1.8 1.8 no signal
656 Osteomyelitis 21 1.8 1.8 no signal
657 Cytokine Release Syndrome 22 1.8 1.8 no signal
658 Fluid Overload 17 1.8 1.8 no signal
659 Dysmenorrhoea 15 1.8 1.8 no signal
660 Insurance Issue 17 1.8 1.8 no signal
661 Pneumonia 369 1.8 1.8 no signal
662 Pallor 31 1.7 1.7 no signal
663 Cardiac Failure Congestive 92 1.7 1.7 no signal
664 Gastric Haemorrhage 13 1.7 1.7 no signal
665 Restlessness 41 1.7 1.7 no signal
666 Injury 79 1.7 1.7 no signal
667 Drug Effect Decreased 61 1.7 1.7 no signal
668 Polyuria 9 1.7 1.7 no signal
669 Product Use In Unapproved Indication 268 1.7 1.7 no signal
670 Somnolence 220 1.7 1.7 no signal
671 Peripheral Coldness 15 1.7 1.7 no signal
672 Product Quality Issue 145 1.7 1.7 no signal
673 Hepatocellular Injury 15 1.6 1.6 no signal
674 Posterior Reversible Encephalopathy Syndrome 10 1.6 1.6 no signal
675 Pulmonary Fibrosis 20 1.6 1.6 no signal
676 Pyelonephritis 9 1.6 1.6 no signal
677 Respiratory Arrest 29 1.6 1.6 no signal
678 Dyspnoea Exertional 39 1.6 1.6 no signal
679 Hypoglycaemia 50 1.6 1.6 no signal
680 Angioedema 45 1.6 1.6 no signal
681 Oedema 55 1.6 1.6 no signal
682 Clostridium Difficile Infection 22 1.6 1.6 no signal
683 White Blood Cell Count Decreased 110 1.6 1.6 no signal
684 Ligament Sprain 10 1.6 1.6 no signal
685 Red Blood Cell Count Decreased 29 1.6 1.6 no signal
686 Pulmonary Thrombosis 11 1.5 1.5 no signal
687 Oesophagitis 11 1.5 1.5 no signal
688 Myelosuppression 34 1.5 1.5 no signal
689 Heart Rate Increased 98 1.5 1.5 no signal
690 Motor Dysfunction 10 1.5 1.5 no signal
691 Blood Potassium Increased 16 1.5 1.5 no signal
692 Delirium 34 1.5 1.5 no signal
693 Myocarditis 11 1.5 1.5 no signal
694 Musculoskeletal Stiffness 85 1.5 1.5 no signal
695 Dyspnoea 548 1.5 1.5 no signal
696 Hepatic Steatosis 18 1.5 1.5 no signal
697 Hypertension 205 1.5 1.5 no signal
698 Coma 46 1.5 1.5 no signal
699 Hypokinesia 14 1.5 1.5 no signal
700 Cerebrovascular Accident 163 1.5 1.5 no signal
701 Proteinuria 18 1.5 1.5 no signal
702 Flushing 97 1.5 1.5 no signal
703 Nausea 745 1.4 1.5 no signal
704 Rash Erythematous 44 1.4 1.4 no signal
705 Chills 110 1.4 1.4 no signal
706 Skin Discolouration 43 1.4 1.4 no signal
707 Sudden Death 10 1.4 1.4 no signal
708 Skin Ulcer 24 1.4 1.4 no signal
709 Altered State Of Consciousness 20 1.4 1.4 no signal
710 Conjunctivitis 17 1.4 1.4 no signal
711 Therapeutic Product Effect Incomplete 65 1.4 1.4 no signal
712 Product Preparation Error 19 1.4 1.4 no signal
713 Blister 51 1.4 1.4 no signal
714 Bronchospasm 13 1.4 1.4 no signal
715 Procedural Pain 25 1.4 1.4 no signal
716 Pneumocystis Jirovecii Pneumonia 9 1.4 1.4 no signal
717 Unevaluable Event 68 1.4 1.4 no signal
718 Infection 129 1.4 1.4 no signal
719 Sleep Apnoea Syndrome 17 1.4 1.4 no signal
720 Injection Site Haematoma 13 1.4 1.4 no signal
721 Burning Sensation 62 1.4 1.4 no signal
722 Chest Discomfort 90 1.4 1.4 no signal
723 Dermatitis Allergic 11 1.4 1.4 no signal
724 Poor Quality Product Administered 9 1.4 1.4 no signal
725 Off Label Use 757 1.3 1.4 no signal
726 Haemorrhoids 17 1.3 1.3 no signal
727 Blood Pressure Systolic Increased 17 1.3 1.3 no signal
728 Productive Cough 41 1.3 1.3 no signal
729 Splenomegaly 10 1.3 1.3 no signal
730 Spinal Pain 10 1.3 1.3 no signal
731 Hyperhidrosis 110 1.3 1.3 no signal
732 Caesarean Section 10 1.3 1.3 no signal
733 Drug Level Increased 14 1.3 1.3 no signal
734 Chronic Kidney Disease 64 1.3 1.3 no signal
735 Lethargy 48 1.3 1.3 no signal
736 Therapy Non-responder 37 1.3 1.3 no signal
737 Urinary Tract Infection 141 1.3 1.3 no signal
738 Loss Of Consciousness 106 1.3 1.3 no signal
739 Face Oedema 14 1.3 1.3 no signal
740 Glomerular Filtration Rate Decreased 10 1.3 1.3 no signal
741 Drug Ineffective For Unapproved Indication 46 1.3 1.3 no signal
742 Rectal Haemorrhage 35 1.2 1.2 no signal
743 Respiratory Tract Infection 21 1.2 1.2 no signal
744 Skin Infection 9 1.2 1.2 no signal
745 Circumstance Or Information Capable Of Leading To Medication Error 27 1.2 1.2 no signal
746 Mental Disorder 35 1.2 1.2 no signal
747 Hepatic Cirrhosis 15 1.2 1.2 no signal
748 Respiratory Disorder 24 1.2 1.2 no signal
749 Arrhythmia 38 1.2 1.2 no signal
750 Vaginal Haemorrhage 34 1.2 1.2 no signal
751 Feeling Hot 49 1.2 1.2 no signal
752 Brain Injury 8 1.2 1.2 no signal
753 Skin Fissures 15 1.2 1.2 no signal
754 Blood Urine Present 15 1.2 1.2 no signal
755 Eyelid Ptosis 8 1.2 1.2 no signal
756 Inappropriate Antidiuretic Hormone Secretion 8 1.2 1.2 no signal
757 Presyncope 19 1.2 1.2 no signal
758 Lactic Acidosis 25 1.2 1.2 no signal
759 Prescribed Overdose 15 1.2 1.2 no signal
760 Neutropenia 105 1.2 1.2 no signal
761 Adverse Event 71 1.2 1.2 no signal
762 Tenderness 8 1.2 1.2 no signal
763 Hepatic Enzyme Increased 52 1.2 1.2 no signal
764 Anorexia 10 1.2 1.2 no signal
765 Drug Ineffective 1,000 1.2 1.2 no signal
766 Abdominal Pain Upper 156 1.2 1.2 no signal
767 Gastroenteritis 11 1.2 1.2 no signal
768 Sensory Disturbance 12 1.1 1.1 no signal
769 Neoplasm Progression 26 1.1 1.1 no signal
770 Accidental Overdose 27 1.1 1.1 no signal
771 Acute Hepatic Failure 10 1.1 1.1 no signal
772 Respiratory Depression 9 1.1 1.1 no signal
773 Disease Recurrence 35 1.1 1.1 no signal
774 Secretion Discharge 9 1.1 1.1 no signal
775 Angina Pectoris 21 1.1 1.1 no signal
776 Wheezing 43 1.1 1.1 no signal
777 Muscle Spasticity 9 1.1 1.1 no signal
778 Hip Arthroplasty 11 1.1 1.1 no signal
779 Sinus Bradycardia 7 1.1 1.1 no signal
780 Epilepsy 22 1.1 1.1 no signal
781 Feeling Cold 20 1.1 1.1 no signal
782 Kidney Infection 14 1.1 1.1 no signal
783 Intestinal Perforation 8 1.1 1.1 no signal
784 Drug Dispensing Error 11 1.1 1.1 no signal
785 Asthenia 264 1.1 1.1 no signal
786 Skin Lesion 19 1.1 1.1 no signal
787 Muscular Weakness 79 1.1 1.1 no signal
788 Intestinal Obstruction 26 1.1 1.1 no signal
789 Convulsion 40 1.1 1.1 no signal
790 Foot Fracture 13 1.0 1.0 no signal
791 Eyelid Oedema 8 1.0 1.0 no signal
792 Abasia 17 1.0 1.0 no signal
793 Polyneuropathy 8 1.0 1.0 no signal
794 Electrocardiogram Qt Prolonged 24 1.0 1.0 no signal
795 Palpitations 78 1.0 1.0 no signal
796 Sinus Congestion 9 1.0 1.0 no signal
797 Drug Resistance 17 1.0 1.0 no signal
798 Gastrooesophageal Reflux Disease 53 1.0 1.0 no signal
799 Fibromyalgia 16 1.0 1.0 no signal
800 Cystitis 21 1.0 1.0 no signal
801 Haematochezia 36 1.0 1.0 no signal
802 Prescribed Underdose 13 1.0 1.0 no signal
803 Dysuria 24 1.0 1.0 no signal
804 Dehydration 86 1.0 1.0 no signal
805 Intervertebral Disc Degeneration 6 1.0 1.0 no signal
806 Pharyngitis 8 1.0 1.0 no signal
807 Eczema 32 1.0 1.0 no signal
808 Infusion Related Reaction 42 1.0 1.0 no signal
809 Lip Swelling 21 1.0 1.0 no signal
810 Blood Potassium Decreased 19 1.0 1.0 no signal
811 Pneumonitis 17 1.0 1.0 no signal
812 Abscess 10 1.0 1.0 no signal
813 Mydriasis 8 1.0 1.0 no signal
814 Skin Haemorrhage 9 1.0 1.0 no signal
815 Cold Sweat 11 1.0 1.0 no signal
816 Blood Pressure Fluctuation 15 1.0 1.0 no signal
817 Hyperthyroidism 9 1.0 1.0 no signal
818 Syncope 62 0.9 0.9 no signal
819 Genital Haemorrhage 8 0.9 0.9 no signal
820 Hiatus Hernia 8 0.9 0.9 no signal
821 Platelet Count Increased 8 0.9 0.9 no signal
822 Blood Pressure Abnormal 12 0.9 0.9 no signal
823 Confusional State 98 0.9 0.9 no signal
824 Skin Disorder 20 0.9 0.9 no signal
825 Emotional Distress 73 0.9 0.9 no signal
826 Tremor 99 0.9 0.9 no signal
827 Emphysema 6 0.9 0.9 no signal
828 Hypophagia 15 0.9 0.9 no signal
829 Plasma Cell Myeloma 23 0.9 0.9 no signal
830 Hypoaesthesia 88 0.9 0.9 no signal
831 Drug Level Decreased 6 0.9 0.9 no signal
832 Paraesthesia 92 0.9 0.9 no signal
833 Diarrhoea 374 0.9 0.9 no signal
834 Dysphagia 55 0.9 0.9 no signal
835 Gastrointestinal Disorder 51 0.9 0.9 no signal
836 Chromaturia 13 0.9 0.9 no signal
837 Seizure 66 0.9 0.9 no signal
838 Urinary Incontinence 17 0.9 0.9 no signal
839 Heart Rate Irregular 13 0.9 0.9 no signal
840 Obesity 9 0.9 0.9 no signal
841 Erythema 115 0.9 0.9 no signal
842 Decreased Activity 6 0.9 0.9 no signal
843 Dysarthria 21 0.9 0.9 no signal
844 Renal Disorder 26 0.9 0.9 no signal
845 Faeces Discoloured 12 0.8 0.8 no signal
846 Injection Site Irritation 7 0.8 0.8 no signal
847 Hypersensitivity 102 0.8 0.8 no signal
848 Pancreatitis 29 0.8 0.8 no signal
849 Immunodeficiency 8 0.8 0.8 no signal
850 Dyskinesia 22 0.8 0.8 no signal
851 Hepatotoxicity 12 0.8 0.8 no signal
852 Contusion 52 0.8 0.8 no signal
853 Urticaria 90 0.8 0.8 no signal
854 Injection Site Induration 7 0.8 0.8 no signal
855 Decreased Appetite 125 0.8 0.8 no signal
856 Diplopia 14 0.8 0.8 no signal
857 Nephropathy Toxic 6 0.8 0.8 no signal
858 Headache 336 0.8 0.8 no signal
859 Lacrimation Increased 16 0.8 0.8 no signal
860 Hepatic Encephalopathy 5 0.8 0.8 no signal
861 Nephropathy 5 0.8 0.8 no signal
862 Fluid Retention 27 0.8 0.8 no signal
863 Stomatitis 32 0.8 0.8 no signal
864 Device Failure 8 0.8 0.8 no signal
865 Eye Haemorrhage 7 0.8 0.8 no signal
866 Dizziness Postural 5 0.8 0.8 no signal
867 Oropharyngeal Pain 48 0.8 0.8 no signal
868 Cholelithiasis 17 0.8 0.8 no signal
869 Cough 145 0.8 0.8 no signal
870 Ankle Fracture 8 0.8 0.8 no signal
871 Urinary Retention 17 0.8 0.8 no signal
872 Blood Pressure Increased 78 0.8 0.8 no signal
873 Disease Progression 60 0.8 0.8 no signal
874 Asthma 57 0.8 0.8 no signal
875 Drug Toxicity 7 0.8 0.8 no signal
876 Disorientation 20 0.8 0.8 no signal
877 Bladder Disorder 5 0.8 0.8 no signal
878 Pruritus Generalised 11 0.8 0.8 no signal
879 Product Administration Error 10 0.8 0.8 no signal
880 Neuropathy Peripheral 47 0.8 0.8 no signal
881 Ovarian Cyst 5 0.8 0.8 no signal
882 Musculoskeletal Pain 26 0.8 0.8 no signal
883 Pain 302 0.8 0.7 no signal
884 Ear Infection 13 0.8 0.8 no signal
885 Tooth Abscess 5 0.8 0.8 no signal
886 No Therapeutic Response 6 0.7 0.7 no signal
887 Scratch 5 0.7 0.7 no signal
888 Malignant Neoplasm Progression 49 0.7 0.7 no signal
889 Pulmonary Arterial Hypertension 7 0.7 0.7 no signal
890 Fungal Infection 16 0.7 0.7 no signal
891 Pericarditis 8 0.7 0.7 no signal
892 Swollen Tongue 15 0.7 0.7 no signal
893 Blood Sodium Decreased 9 0.7 0.7 no signal
894 Swelling Face 31 0.7 0.7 no signal
895 Treatment Failure 39 0.7 0.7 no signal
896 Overdose 102 0.7 0.7 no signal
897 Inappropriate Schedule Of Product Administration 83 0.7 0.7 no signal
898 Wound 13 0.7 0.7 no signal
899 Dizziness 231 0.7 0.7 no signal
900 Malaise 203 0.7 0.7 no signal
901 Injection Site Rash 14 0.7 0.7 no signal
902 Neurotoxicity 8 0.7 0.7 no signal
903 Joint Stiffness 12 0.7 0.7 no signal
904 Rash 197 0.7 0.7 no signal
905 Anxiety 129 0.7 0.7 no signal
906 Back Pain 105 0.7 0.7 no signal
907 Blood Glucose Increased 85 0.7 0.7 no signal
908 Activities Of Daily Living Impaired 9 0.7 0.7 no signal
909 Agitation 33 0.7 0.7 no signal
910 Osteoarthritis 19 0.7 0.7 no signal
911 Covid-19 79 0.7 0.7 no signal
912 Full Blood Count Decreased 9 0.7 0.7 no signal
913 Throat Tightness 12 0.7 0.7 no signal
914 Fistula 5 0.7 0.7 no signal
915 Bronchitis 33 0.7 0.7 no signal
916 Blindness 18 0.7 0.7 no signal
917 Pruritus 167 0.7 0.7 no signal
918 Hypothyroidism 14 0.7 0.7 no signal
919 Speech Disorder 23 0.7 0.7 no signal
920 Retinal Detachment 4 0.7 0.7 no signal
921 Dermatitis 9 0.7 0.7 no signal
922 Nerve Compression 4 0.7 0.7 no signal
923 Movement Disorder 14 0.7 0.7 no signal
924 Metastases To Lung 5 0.7 0.7 no signal
925 Hallucination, Visual 9 0.7 0.7 no signal
926 Death 368 0.7 0.6 no signal
927 Coordination Abnormal 6 0.7 0.7 no signal
928 Diarrhoea Haemorrhagic 4 0.7 0.7 no signal
929 Rash Pruritic 23 0.7 0.7 no signal
930 Pain In Jaw 12 0.6 0.6 no signal
931 Eating Disorder 9 0.6 0.6 no signal
932 Laceration 4 0.6 0.6 no signal
933 Myalgia 71 0.6 0.6 no signal
934 Diabetic Ketoacidosis 10 0.6 0.6 no signal
935 Nasopharyngitis 77 0.6 0.6 no signal
936 Myelodysplastic Syndrome 6 0.6 0.6 no signal
937 Bone Pain 24 0.6 0.6 no signal
938 Inflammation 21 0.6 0.6 no signal
939 Pain In Extremity 118 0.6 0.6 no signal
940 Impaired Healing 13 0.6 0.6 no signal
941 Diabetes Mellitus Inadequate Control 7 0.6 0.6 no signal
942 Hypothermia 4 0.6 0.6 no signal
943 Nephrolithiasis 18 0.6 0.6 no signal
944 Metastases To Central Nervous System 5 0.6 0.6 no signal
945 Influenza Like Illness 32 0.6 0.6 no signal
946 Folliculitis 4 0.6 0.6 no signal
947 Lymphoma 6 0.6 0.6 no signal
948 Product Use Complaint 6 0.6 0.6 no signal
949 Palmar-plantar Erythrodysaesthesia Syndrome 9 0.6 0.6 no signal
950 Pollakiuria 16 0.6 0.6 no signal
951 Adverse Reaction 5 0.6 0.6 no signal
952 Weight Decreased 105 0.6 0.6 no signal
953 Rash Macular 13 0.6 0.6 no signal
954 Breast Cancer Metastatic 4 0.6 0.6 no signal
955 Hunger 5 0.6 0.6 no signal
956 Fall 123 0.6 0.6 no signal
957 Insomnia 98 0.6 0.6 no signal
958 Metastases To Bone 6 0.6 0.6 no signal
959 Vision Blurred 50 0.6 0.6 no signal
960 Musculoskeletal Disorder 7 0.6 0.6 no signal
961 Peripheral Swelling 56 0.6 0.6 no signal
962 Herpes Zoster 21 0.6 0.6 no signal
963 Discomfort 22 0.6 0.6 no signal
964 Cardiac Disorder 34 0.6 0.6 no signal
965 Diverticulitis 10 0.6 0.6 no signal
966 Central Nervous System Lesion 5 0.6 0.6 no signal
967 Red Blood Cell Sedimentation Rate Increased 4 0.6 0.6 no signal
968 Muscle Spasms 66 0.6 0.5 no signal
969 Rash Papular 8 0.5 0.5 no signal
970 Lymphopenia 5 0.5 0.5 no signal
971 Disability 7 0.5 0.5 no signal
972 Product Use Issue 66 0.5 0.5 no signal
973 Intentional Product Use Issue 31 0.5 0.5 no signal
974 Impaired Quality Of Life 5 0.5 0.5 no signal
975 Deafness 9 0.5 0.5 no signal
976 Metastases To Liver 6 0.5 0.5 no signal
977 Underdose 25 0.5 0.5 no signal
978 Night Sweats 11 0.5 0.5 no signal
979 Osteoporosis 14 0.5 0.5 no signal
980 Laboratory Test Abnormal 10 0.5 0.5 no signal
981 Systemic Lupus Erythematosus 12 0.5 0.5 no signal
982 Local Swelling 6 0.5 0.5 no signal
983 Colon Cancer 5 0.5 0.5 no signal
984 Fatigue 260 0.5 0.5 no signal
985 Limb Injury 9 0.5 0.5 no signal
986 Weight Increased 74 0.5 0.5 no signal
987 Neoplasm Malignant 22 0.5 0.5 no signal
988 Vertigo 20 0.5 0.5 no signal
989 Abortion Spontaneous 13 0.5 0.5 no signal
990 Acute Myeloid Leukaemia 5 0.5 0.5 no signal
991 Ocular Hyperaemia 15 0.5 0.5 no signal
992 Osteonecrosis Of Jaw 8 0.5 0.5 no signal
993 Deformity 3 0.5 0.5 no signal
994 Ageusia 8 0.5 0.5 no signal
995 Abortion Induced 3 0.5 0.5 no signal
996 Gait Disturbance 61 0.5 0.5 no signal
997 Dyspepsia 31 0.5 0.5 no signal
998 Abdominal Pain Lower 8 0.5 0.5 no signal
999 Loss Of Personal Independence In Daily Activities 15 0.5 0.5 no signal
1000 Hypersomnia 9 0.5 0.5 no signal
1001 Lymphadenopathy 11 0.5 0.5 no signal
1002 Dysstasia 9 0.5 0.5 no signal
1003 Sedation 8 0.5 0.5 no signal
1004 Product Dose Omission Issue 87 0.5 0.5 no signal
1005 Eye Disorder 10 0.5 0.5 no signal
1006 Neck Pain 17 0.5 0.5 no signal
1007 Viral Infection 10 0.5 0.5 no signal
1008 Balance Disorder 26 0.5 0.5 no signal
1009 Type 2 Diabetes Mellitus 10 0.5 0.5 no signal
1010 Disturbance In Attention 16 0.5 0.5 no signal
1011 Hallucination 22 0.4 0.4 no signal
1012 Dysphonia 17 0.4 0.4 no signal
1013 Blood Glucose Decreased 14 0.4 0.4 no signal
1014 Injection Site Haemorrhage 23 0.4 0.4 no signal
1015 Dry Skin 38 0.4 0.4 no signal
1016 Skin Exfoliation 24 0.4 0.4 no signal
1017 Injection Site Urticaria 7 0.4 0.4 no signal
1018 Head Injury 9 0.4 0.4 no signal
1019 Rhinorrhoea 18 0.4 0.4 no signal
1020 Product Substitution Issue 16 0.4 0.4 no signal
1021 Product Packaging Quantity Issue 3 0.4 0.4 no signal
1022 Blood Glucose Abnormal 5 0.4 0.4 no signal
1023 Illness 27 0.4 0.4 no signal
1024 Colitis 10 0.4 0.4 no signal
1025 Rebound Effect 3 0.4 0.4 no signal
1026 Depression 58 0.4 0.4 no signal
1027 Migraine 24 0.4 0.4 no signal
1028 Neuroleptic Malignant Syndrome 3 0.4 0.4 no signal
1029 Extra Dose Administered 10 0.4 0.4 no signal
1030 Injury Associated With Device 5 0.4 0.4 no signal
1031 Pregnancy 5 0.4 0.4 no signal
1032 Incorrect Product Administration Duration 5 0.4 0.4 no signal
1033 Drug Effect Incomplete 9 0.4 0.4 no signal
1034 Injection Site Erythema 30 0.4 0.4 no signal
1035 Influenza 27 0.4 0.4 no signal
1036 Osteonecrosis 8 0.4 0.4 no signal
1037 Multiple Fractures 4 0.4 0.4 no signal
1038 Abdominal Discomfort 40 0.4 0.4 no signal
1039 Nasal Congestion 14 0.4 0.4 no signal
1040 Road Traffic Accident 10 0.4 0.4 no signal
1041 Incorrect Dose Administered 52 0.4 0.4 no signal
1042 Injection Site Pruritus 15 0.3 0.3 no signal
1043 Drug Administration Error 7 0.3 0.3 no signal
1044 Pain Of Skin 6 0.3 0.3 no signal
1045 Pelvic Pain 4 0.3 0.3 no signal
1046 Feeling Abnormal 52 0.3 0.3 no signal
1047 Injection Site Bruising 17 0.3 0.3 no signal
1048 Arthralgia 89 0.3 0.3 no signal
1049 Mobility Decreased 15 0.3 0.3 no signal
1050 Serotonin Syndrome 4 0.3 0.3 no signal
1051 Hepatic Cancer 5 0.3 0.3 no signal
1052 Throat Irritation 9 0.3 0.3 no signal
1053 Adverse Drug Reaction 18 0.3 0.3 no signal
1054 Menorrhagia 4 0.3 0.3 no signal
1055 Eye Pain 11 0.3 0.3 no signal
1056 Glycosylated Haemoglobin Increased 5 0.3 0.3 no signal
1057 Hospitalisation 30 0.3 0.3 no signal
1058 Gastric Cancer 5 0.3 0.3 no signal
1059 Cognitive Disorder 9 0.3 0.3 no signal
1060 Nervousness 10 0.3 0.3 no signal
1061 Depressed Mood 10 0.3 0.3 no signal
1062 Injection Site Reaction 13 0.3 0.3 no signal
1063 Sinusitis 19 0.3 0.3 no signal
1064 Aggression 9 0.3 0.3 no signal
1065 Toxicity To Various Agents 30 0.3 0.3 no signal
1066 Device Breakage 7 0.3 0.3 no signal
1067 Needle Issue 5 0.3 0.3 no signal
1068 Therapy Interrupted 12 0.3 0.3 no signal
1069 Syringe Issue 3 0.3 0.3 no signal
1070 Cataract 10 0.3 0.3 no signal
1071 Amnesia 11 0.3 0.3 no signal
1072 Joint Swelling 20 0.3 0.3 no signal
1073 Flatulence 9 0.2 0.2 no signal
1074 Alopecia 31 0.2 0.2 no signal
1075 Incorrect Dose Administered By Device 4 0.2 0.2 no signal
1076 Device Delivery System Issue 4 0.2 0.2 no signal
1077 Device Malfunction 10 0.2 0.2 no signal
1078 Dysgeusia 11 0.2 0.2 no signal
1079 No Adverse Event 25 0.2 0.2 no signal
1080 Arthritis 11 0.2 0.2 no signal
1081 Device Dislocation 6 0.2 0.2 no signal
1082 Device Issue 12 0.2 0.2 no signal
1083 Skin Burning Sensation 9 0.2 0.2 no signal
1084 Extrapyramidal Disorder 3 0.2 0.2 no signal
1085 Visual Impairment 14 0.2 0.2 no signal
1086 Injection Site Pain 32 0.2 0.2 no signal
1087 Memory Impairment 14 0.2 0.2 no signal
1088 Device Leakage 4 0.1 0.1 no signal
1089 Wrong Technique In Product Usage Process 11 0.1 0.1 no signal
1090 Drug Dependence 8 0.1 0.1 no signal