Drug

Hydrocodone Bitartrate And Ibuprofen

12 flagged reaction(s) · 578 total co-reports · max PRR 218.5

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Dependence	269	218.5	513.9	signal
2	Product Prescribing Issue	18	39.7	41.3	signal
3	Overdose	166	34.4	52.9	signal
4	Ill-defined Disorder	33	24.4	26.2	signal
5	Withdrawal Syndrome	19	20.2	21.0	signal
6	Drug Withdrawal Syndrome Neonatal	5	15.0	15.2	signal
7	Tooth Loss	6	12.9	13.1	signal
8	Drug Dependence	33	9.1	9.7	signal
9	Intentional Drug Misuse	3	6.4	6.4	signal
10	Drug Withdrawal Syndrome	10	5.1	5.2	signal
11	Drug Abuse	8	4.3	4.4	signal
12	Completed Suicide	8	4.3	4.3	signal