OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Instalax Polyethylene Glycol 3350

1,083 flagged reaction(s) · 56,071 total co-reports · max PRR 2,479.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Antacid Therapy 71 2,479.9 2,494.3 signal
2 Sleep Disorder Therapy 109 2,436.6 2,458.3 signal
3 Appendicolith 204 2,000.1 2,033.7 signal
4 Medically Induced Preterm Birth 7 1,304.0 1,304.7 signal
5 Analgesic Therapy 110 955.6 964.1 signal
6 Drug Therapy 102 799.1 805.8 signal
7 Anticoagulant Therapy 71 586.4 589.8 signal
8 Exposure To Unspecified Agent 46 517.6 519.5 signal
9 Congenital Hiatus Hernia 50 496.0 498.0 signal
10 Vaginal Flatulence 68 487.2 489.9 signal
11 Malignant Melanoma Stage 0 37 436.8 438.2 signal
12 Foreign Body Ingestion 15 279.4 279.8 signal
13 Bacteroides Infection 28 205.9 206.4 signal
14 Victim Of Child Abuse 24 182.9 183.3 signal
15 Cerebral Hypoperfusion 43 175.8 176.4 signal
16 Binocular Eye Movement Disorder 26 173.7 174.0 signal
17 Child Abuse 20 147.7 148.0 signal
18 Neutropenia Neonatal 17 138.4 138.5 signal
19 Pelvic Kidney 8 127.7 127.8 signal
20 Cerebellar Stroke 26 126.7 127.0 signal
21 Hyperphosphataemia 146 125.8 127.3 signal
22 Epidural Lipomatosis 23 120.1 120.3 signal
23 Incorrect Product Administration Duration 1,267 113.2 126.1 signal
24 Blood Phosphorus Increased 170 113.1 114.7 signal
25 Bronchopulmonary Aspergillosis Allergic 48 93.9 94.3 signal
26 Cerebral Artery Thrombosis 26 90.1 90.3 signal
27 Brain Scan Abnormal 26 82.7 82.9 signal
28 Female Genital Tract Fistula 70 72.0 72.4 signal
29 Nasal Herpes 8 69.9 69.9 signal
30 Hyponatraemic Seizure 8 55.2 55.2 signal
31 Chronic Sinusitis 116 54.3 54.8 signal
32 Noninfectious Peritonitis 7 50.4 50.4 signal
33 Proctitis 76 47.3 47.6 signal
34 Radiculopathy 69 45.7 45.9 signal
35 Total Lung Capacity Decreased 41 44.6 44.8 signal
36 Foetal Disorder 21 43.3 43.4 signal
37 Catarrh 22 43.1 43.2 signal
38 Iron Deficiency 109 42.7 43.1 signal
39 Blood Uric Acid Increased 135 40.7 41.2 signal
40 Appendicitis 210 39.3 39.9 signal
41 Steroid Dependence 19 38.8 38.9 signal
42 Incorrect Drug Administration Duration 625 38.1 40.0 signal
43 Gingival Abscess 16 36.6 36.6 signal
44 Faecal Volume Decreased 10 35.9 35.9 signal
45 Activated Partial Thromboplastin Time Prolonged 100 34.1 34.4 signal
46 Diabetic Ketosis 7 33.7 33.7 signal
47 Aortic Stenosis 67 33.3 33.5 signal
48 Hypophosphataemia 139 32.8 33.1 signal
49 Myasthenia Gravis 147 32.3 32.7 signal
50 Ventricular Fibrillation 202 31.4 31.9 signal
51 Lung Opacity 43 28.9 29.0 signal
52 Hyporesponsive To Stimuli 19 28.6 28.6 signal
53 Urinary Tract Infection Staphylococcal 7 28.5 28.5 signal
54 Cardiogenic Shock 212 25.6 26.1 signal
55 Product Administered To Patient Of Inappropriate Age 87 25.0 25.1 signal
56 Pneumonia Haemophilus 7 24.8 24.8 signal
57 Sciatic Nerve Injury 12 24.7 24.7 signal
58 Wrong Patient 7 24.5 24.5 signal
59 Pleuritic Pain 39 24.2 24.3 signal
60 Burns Second Degree 24 23.6 23.7 signal
61 Macular Degeneration 162 23.4 23.7 signal
62 Therapeutic Product Effect Variable 51 23.0 23.1 signal
63 Product Ineffective For Unapproved Use 18 22.2 22.2 signal
64 Therapeutic Product Effect Delayed 54 20.6 20.7 signal
65 Intestinal Pseudo-obstruction 10 20.0 20.0 signal
66 Troponin Increased 85 19.4 19.5 signal
67 Tongue Paralysis 8 19.2 19.2 signal
68 Oesophageal Achalasia 7 18.7 18.8 signal
69 Pseudomonal Bacteraemia 9 18.4 18.4 signal
70 Enterococcus Test Positive 7 18.4 18.4 signal
71 Respiratory Symptom 30 18.4 18.4 signal
72 Blood Pressure Diastolic Abnormal 27 18.0 18.1 signal
73 Faeces Soft 75 17.8 17.9 signal
74 Blister Infected 8 17.5 17.5 signal
75 Breath Sounds Abnormal 50 17.4 17.5 signal
76 Slow Response To Stimuli 13 17.3 17.3 signal
77 Areflexia 27 17.2 17.3 signal
78 Product After Taste 9 16.5 16.5 signal
79 Juvenile Idiopathic Arthritis 23 16.1 16.1 signal
80 Neutropenic Infection 9 16.0 16.0 signal
81 Benign Prostatic Hyperplasia 48 15.9 15.9 signal
82 Anal Incontinence 82 15.8 15.9 signal
83 Bacterial Infection 162 15.0 15.1 signal
84 Incorrect Route Of Product Administration 146 14.9 15.1 signal
85 Alcohol Poisoning 23 14.9 14.9 signal
86 Blood Calcium Increased 73 14.2 14.3 signal
87 Multiple Organ Dysfunction Syndrome 229 14.1 14.3 signal
88 Underdose 596 14.0 14.6 signal
89 Mycobacterial Infection 14 13.9 13.9 signal
90 Frequent Bowel Movements 217 13.8 14.0 signal
91 Abnormal Faeces 66 13.8 13.9 signal
92 Faecaloma 43 13.5 13.6 signal
93 Ascites 230 13.4 13.6 signal
94 Muscle Necrosis 7 13.2 13.2 signal
95 Psychiatric Decompensation 15 13.2 13.2 signal
96 Blood Pressure Systolic Abnormal 19 13.1 13.1 signal
97 Hyperlipidaemia 91 13.0 13.1 signal
98 Drug Effect Less Than Expected 106 12.9 13.0 signal
99 Vaginal Discharge 74 12.6 12.7 signal
100 Neuralgia 177 12.5 12.7 signal
101 Paraesthesia Oral 104 12.4 12.5 signal
102 Hypopnoea 25 12.4 12.4 signal
103 Faeces Hard 28 12.3 12.4 signal
104 Bronchiectasis 47 12.1 12.1 signal
105 On And Off Phenomenon 37 12.0 12.1 signal
106 Drug Effect Variable 8 11.9 11.9 signal
107 Micturition Urgency 79 11.9 12.0 signal
108 Rectal Prolapse 8 11.3 11.3 signal
109 Respiratory Acidosis 26 11.3 11.4 signal
110 Fractured Sacrum 8 11.1 11.1 signal
111 Renal Mass 13 10.8 10.8 signal
112 Hepatic Cytolysis 77 10.8 10.8 signal
113 Troponin T Increased 8 10.8 10.8 signal
114 Expired Product Administered 207 10.7 10.8 signal
115 Oral Candidiasis 80 10.5 10.6 signal
116 Hyponatraemia 342 10.4 10.7 signal
117 Drug Administered To Patient Of Inappropriate Age 42 9.9 9.9 signal
118 Vascular Purpura 8 9.8 9.8 signal
119 Hypercapnia 17 9.7 9.7 signal
120 Bicytopenia 11 9.7 9.7 signal
121 Pneumonia Viral 18 9.7 9.7 signal
122 Dyschezia 17 9.6 9.6 signal
123 Aplastic Anaemia 28 9.1 9.1 signal
124 Ulcer 84 9.0 9.1 signal
125 Aspiration 57 9.0 9.0 signal
126 Autonomic Nervous System Imbalance 15 8.9 8.9 signal
127 Suspected Off Label Use 9 8.9 8.9 signal
128 Carbon Dioxide Increased 7 8.8 8.8 signal
129 Gout 91 8.6 8.7 signal
130 Intestinal Ulcer 8 8.6 8.6 signal
131 Rash Morbilliform 14 8.6 8.6 signal
132 Clostridium Test Positive 11 8.6 8.6 signal
133 Intensive Care 7 8.6 8.6 signal
134 End Stage Renal Disease 92 8.5 8.6 signal
135 Abdominal Distension 519 8.5 8.9 signal
136 Blood Test Abnormal 69 8.4 8.4 signal
137 Behaviour Disorder 26 8.4 8.4 signal
138 Wrong Patient Received Product 14 8.4 8.4 signal
139 Vascular Device Infection 22 8.3 8.3 signal
140 Mean Cell Haemoglobin Concentration Decreased 8 8.2 8.2 signal
141 Flatulence 272 8.2 8.4 signal
142 Lung Consolidation 13 7.9 7.9 signal
143 Antipsychotic Drug Level Increased 13 7.9 7.9 signal
144 Swollen Tongue 141 7.7 7.8 signal
145 Anal Fissure 24 7.7 7.7 signal
146 Cardiac Murmur 39 7.7 7.7 signal
147 Frustration Tolerance Decreased 36 7.6 7.7 signal
148 Mixed Liver Injury 13 7.6 7.6 signal
149 Hepatic Lesion 19 7.5 7.5 signal
150 Full Blood Count Abnormal 46 7.4 7.5 signal
151 Dysentery 8 7.4 7.4 signal
152 Jaundice Neonatal 8 7.2 7.2 signal
153 Therapeutic Product Effect Decreased 187 7.2 7.3 signal
154 Pancreatic Cyst 8 7.2 7.2 signal
155 Pyelonephritis Acute 8 7.0 7.0 signal
156 Cerebellar Syndrome 9 6.9 6.9 signal
157 Stress 287 6.8 6.9 signal
158 Rales 23 6.8 6.8 signal
159 Intracranial Pressure Increased 22 6.7 6.7 signal
160 Cutaneous Vasculitis 14 6.7 6.7 signal
161 Hypercholesterolaemia 37 6.6 6.6 signal
162 Red Cell Distribution Width Increased 16 6.6 6.6 signal
163 Febrile Neutropenia 250 6.4 6.6 signal
164 Procedural Pain 104 6.4 6.5 signal
165 Proctalgia 24 6.4 6.4 signal
166 Cholestatic Liver Injury 8 6.4 6.4 signal
167 Rhinovirus Infection 14 6.3 6.3 signal
168 Chronic Obstructive Pulmonary Disease 191 6.2 6.3 signal
169 Facial Paralysis 31 6.2 6.2 signal
170 Ischaemic Stroke 65 6.2 6.2 signal
171 Iron Deficiency Anaemia 33 6.1 6.1 signal
172 Aphthous Ulcer 27 6.0 6.0 signal
173 Blood Creatinine Decreased 11 6.0 6.0 signal
174 Sputum Discoloured 33 6.0 6.0 signal
175 Rhinitis 28 5.9 5.9 signal
176 Escherichia Bacteraemia 8 5.9 5.9 signal
177 Blood Cholesterol Increased 157 5.7 5.8 signal
178 Cytokine Release Syndrome 64 5.7 5.8 signal
179 Constipation 721 5.7 6.0 signal
180 Faeces Discoloured 72 5.7 5.7 signal
181 Gingival Pain 26 5.6 5.6 signal
182 Product Preparation Issue 19 5.6 5.6 signal
183 Hemiplegia 27 5.5 5.5 signal
184 Nocturia 39 5.5 5.5 signal
185 Endotracheal Intubation 9 5.5 5.5 signal
186 Anal Haemorrhage 9 5.5 5.5 signal
187 Immune Effector Cell-associated Neurotoxicity Syndrome 18 5.5 5.5 signal
188 Micturition Disorder 11 5.4 5.4 signal
189 Rectal Haemorrhage 137 5.4 5.5 signal
190 Therapeutic Reaction Time Decreased 9 5.2 5.2 signal
191 Parosmia 23 5.2 5.2 signal
192 Toxic Encephalopathy 15 5.2 5.2 signal
193 Bowel Movement Irregularity 23 5.1 5.1 signal
194 Large Intestinal Ulcer 8 5.0 5.0 signal
195 Sepsis 329 5.0 5.1 signal
196 Type Iv Hypersensitivity Reaction 8 5.0 5.0 signal
197 Small Intestinal Obstruction 36 5.0 5.0 signal
198 General Physical Health Deterioration 336 5.0 5.1 signal
199 Hypoalbuminaemia 22 4.9 4.9 signal
200 Drug Intolerance 276 4.9 5.0 signal
201 Haematochezia 158 4.9 4.9 signal
202 Eosinophilia 49 4.8 4.8 signal
203 Blood Pressure Diastolic Increased 13 4.8 4.8 signal
204 Colitis 105 4.7 4.8 signal
205 Pulmonary Pain 8 4.7 4.7 signal
206 Heart Valve Incompetence 8 4.7 4.7 signal
207 Drug Ineffective For Unapproved Indication 155 4.7 4.8 signal
208 Respiratory Depression 34 4.7 4.7 signal
209 Low Birth Weight Baby 22 4.7 4.7 signal
210 Dysphonia 161 4.7 4.7 signal
211 Dysphemia 12 4.7 4.7 signal
212 Infective Pulmonary Exacerbation Of Cystic Fibrosis 15 4.7 4.7 signal
213 Drug Level Below Therapeutic 15 4.6 4.7 signal
214 Mean Cell Volume Increased 7 4.6 4.6 signal
215 Defaecation Urgency 19 4.6 4.6 signal
216 Product Prescribing Error 64 4.6 4.6 signal
217 Hydronephrosis 20 4.6 4.6 signal
218 Hepatitis Cholestatic 16 4.5 4.5 signal
219 Pulmonary Embolism 254 4.5 4.6 signal
220 Product Administration Error 53 4.5 4.5 signal
221 Gastrointestinal Motility Disorder 14 4.5 4.5 signal
222 Dry Mouth 213 4.5 4.5 signal
223 Febrile Bone Marrow Aplasia 11 4.5 4.5 signal
224 Hypoxia 92 4.5 4.5 signal
225 Abdominal Pain 609 4.5 4.6 signal
226 Body Temperature Decreased 26 4.5 4.5 signal
227 Blood Pressure Systolic Increased 51 4.4 4.4 signal
228 Inappropriate Schedule Of Product Administration 454 4.4 4.5 signal
229 Depressive Symptom 9 4.4 4.4 signal
230 Angioedema 113 4.4 4.4 signal
231 Periorbital Swelling 14 4.3 4.3 signal
232 Colitis Ulcerative 113 4.3 4.3 signal
233 Diverticulum Intestinal 11 4.3 4.3 signal
234 Feeling Cold 70 4.3 4.3 signal
235 Obstructive Airways Disorder 28 4.3 4.3 signal
236 Sleep Disorder 174 4.2 4.3 signal
237 Infusion Site Haemorrhage 8 4.2 4.2 signal
238 Gastrointestinal Sounds Abnormal 12 4.2 4.2 signal
239 Mucous Stools 12 4.1 4.2 signal
240 Hospice Care 24 4.1 4.2 signal
241 Pulmonary Mass 36 4.1 4.1 signal
242 Hypernatraemia 12 4.1 4.1 signal
243 Rash Maculo-papular 53 4.1 4.1 signal
244 Liver Function Test Increased 51 4.1 4.1 signal
245 Therapeutic Product Effect Incomplete 167 4.0 4.1 signal
246 Transaminases Increased 52 4.0 4.0 signal
247 Drug Effect Decreased 127 4.0 4.0 signal
248 Blood Culture Positive 7 3.9 3.9 signal
249 Impaired Quality Of Life 33 3.9 3.9 signal
250 Gastrointestinal Pain 25 3.9 3.9 signal
251 Atelectasis 22 3.9 3.9 signal
252 Colitis Ischaemic 15 3.8 3.8 signal
253 Intentional Product Misuse 193 3.8 3.8 signal
254 Abdominal Rigidity 6 3.8 3.8 signal
255 Enteritis 14 3.8 3.8 signal
256 Hypokalaemia 101 3.7 3.8 signal
257 Joint Injury 47 3.7 3.8 signal
258 Tic 12 3.7 3.7 signal
259 Hyperuricaemia 9 3.7 3.7 signal
260 Drug Effect Delayed 10 3.7 3.7 signal
261 Ventricular Hypokinesia 7 3.7 3.7 signal
262 Infusion Site Erythema 18 3.7 3.7 signal
263 Diabetes Mellitus 166 3.7 3.7 signal
264 Leukocytosis 39 3.7 3.7 signal
265 Posture Abnormal 7 3.7 3.7 signal
266 Presyncope 52 3.7 3.7 signal
267 Lymphocyte Count Decreased 38 3.7 3.7 signal
268 Anaemia 408 3.6 3.7 signal
269 Infusion Related Reaction 141 3.6 3.7 signal
270 Impaired Gastric Emptying 27 3.6 3.6 signal
271 Sinus Tachycardia 30 3.6 3.6 signal
272 Blood Creatinine Increased 138 3.6 3.6 signal
273 Electrocardiogram St Segment Elevation 7 3.6 3.6 signal
274 Tenderness 22 3.6 3.6 signal
275 Left Ventricular Hypertrophy 9 3.6 3.6 signal
276 Thrombosis 169 3.6 3.6 signal
277 Transfusion 22 3.6 3.6 signal
278 Pyelonephritis 18 3.6 3.6 signal
279 Clostridium Difficile Colitis 22 3.5 3.5 signal
280 Hypokinesia 30 3.5 3.5 signal
281 Bacteraemia 24 3.5 3.5 signal
282 Oral Mucosal Blistering 13 3.5 3.5 signal
283 Generalised Oedema 25 3.5 3.5 signal
284 Respiratory Rate Increased 18 3.4 3.4 signal
285 Swelling Face 130 3.4 3.4 signal
286 Vitamin B12 Deficiency 8 3.4 3.4 signal
287 Dizziness Postural 19 3.4 3.4 signal
288 Infusion Site Swelling 12 3.3 3.3 signal
289 Neutrophil Count Increased 20 3.3 3.3 signal
290 Obesity 31 3.3 3.3 signal
291 Skin Abrasion 9 3.3 3.3 signal
292 Intestinal Obstruction 72 3.3 3.3 signal
293 Pulseless Electrical Activity 8 3.3 3.3 signal
294 Hallucinations, Mixed 8 3.2 3.2 signal
295 Blood Albumin Decreased 15 3.2 3.2 signal
296 Malnutrition 21 3.2 3.2 signal
297 Glucose Tolerance Impaired 11 3.2 3.2 signal
298 Inappropriate Schedule Of Drug Administration 135 3.2 3.2 signal
299 Anorectal Discomfort 10 3.2 3.2 signal
300 Snoring 7 3.2 3.2 signal
301 Incorrect Dose Administered 416 3.1 3.2 signal
302 Staphylococcal Bacteraemia 8 3.1 3.1 signal
303 Faecal Incontinence 9 3.1 3.1 signal
304 Thyroid Mass 7 3.1 3.1 signal
305 Encephalopathy 45 3.1 3.1 signal
306 Acute Respiratory Failure 35 3.1 3.1 signal
307 Swelling 169 3.1 3.1 signal
308 Diabetic Neuropathy 9 3.1 3.1 signal
309 Muscle Rupture 7 3.1 3.1 signal
310 Gamma-glutamyltransferase Increased 40 3.1 3.1 signal
311 Urinary Retention 60 3.1 3.1 signal
312 Ileus Paralytic 8 3.1 3.1 signal
313 Lower Respiratory Tract Infection 81 3.0 3.1 signal
314 Abdominal Pain Lower 45 3.0 3.0 signal
315 Hallucination, Visual 37 3.0 3.0 signal
316 Hypertransaminasaemia 12 3.0 3.0 signal
317 Abdominal Hernia 8 3.0 3.0 signal
318 Respiratory Distress 48 3.0 3.0 signal
319 Aspartate Aminotransferase Increased 92 2.9 3.0 signal
320 Agranulocytosis 32 2.9 3.0 signal
321 Blood Potassium Increased 28 2.9 2.9 signal
322 Loss Of Personal Independence In Daily Activities 82 2.9 2.9 signal
323 Haemoglobin Abnormal 11 2.9 2.9 signal
324 Haemoptysis 48 2.9 2.9 signal
325 Bladder Disorder 17 2.9 2.9 signal
326 Tubulointerstitial Nephritis 32 2.9 2.9 signal
327 Neuroleptic Malignant Syndrome 20 2.9 2.9 signal
328 Acute Generalised Exanthematous Pustulosis 13 2.9 2.9 signal
329 Pleural Effusion 102 2.8 2.9 signal
330 Heart Rate Decreased 59 2.8 2.9 signal
331 Abdominal Pain Upper 342 2.8 2.9 signal
332 Bursitis 20 2.8 2.8 signal
333 Humerus Fracture 8 2.8 2.8 signal
334 Immunodeficiency 24 2.8 2.8 signal
335 Upper Respiratory Tract Infection 75 2.8 2.8 signal
336 Cystic Fibrosis 9 2.8 2.8 signal
337 Paronychia 7 2.8 2.8 signal
338 Hypophagia 41 2.7 2.8 signal
339 Streptococcal Infection 9 2.7 2.8 signal
340 Abdominal Tenderness 8 2.7 2.7 signal
341 Somnolence 323 2.7 2.8 signal
342 Coronary Artery Disease 49 2.7 2.7 signal
343 Pneumonia Aspiration 40 2.7 2.7 signal
344 Haematocrit Decreased 32 2.7 2.7 signal
345 Product Solubility Abnormal 8 2.7 2.7 signal
346 Dyspepsia 153 2.7 2.7 signal
347 Herpes Simplex 10 2.6 2.6 signal
348 Productive Cough 73 2.6 2.6 signal
349 Diplopia 40 2.6 2.6 signal
350 Acute Kidney Injury 234 2.6 2.6 signal
351 Failure To Thrive 8 2.6 2.6 signal
352 Hyperkalaemia 53 2.6 2.6 signal
353 Urosepsis 14 2.6 2.6 signal
354 Intestinal Perforation 17 2.6 2.6 signal
355 Pleurisy 9 2.6 2.6 signal
356 Osteopenia 23 2.6 2.6 signal
357 Off Label Use 1,307 2.6 2.7 signal
358 Condition Aggravated 453 2.6 2.6 signal
359 Performance Status Decreased 7 2.5 2.5 signal
360 Skin Reaction 21 2.5 2.5 signal
361 Arteriosclerosis 14 2.5 2.5 signal
362 Urine Output Decreased 13 2.5 2.5 signal
363 Clostridium Difficile Infection 32 2.5 2.5 signal
364 Shock Haemorrhagic 12 2.5 2.5 signal
365 Escherichia Infection 12 2.5 2.5 signal
366 Drug Level Decreased 15 2.5 2.5 signal
367 Cholestasis 28 2.5 2.5 signal
368 General Symptom 11 2.5 2.5 signal
369 Food Allergy 11 2.5 2.5 signal
370 Drooling 10 2.5 2.5 signal
371 Thrombocytopenia 162 2.5 2.5 signal
372 Enterococcal Infection 7 2.5 2.5 signal
373 Haemorrhoidal Haemorrhage 7 2.4 2.4 signal
374 Delusion 22 2.4 2.4 signal
375 Transient Ischaemic Attack 48 2.4 2.4 signal
376 Intestinal Haemorrhage 8 2.4 2.4 signal
377 Intentional Product Use Issue 124 2.4 2.4 signal
378 Protein Urine Present 7 2.4 2.4 signal
379 Bronchospasm 20 2.4 2.4 signal
380 Blood Potassium Decreased 42 2.4 2.4 signal
381 Contraindicated Product Administered 42 2.4 2.4 signal
382 Diarrhoea 891 2.4 2.5 signal
383 Hypothermia 14 2.3 2.3 signal
384 Hypotension 275 2.3 2.4 signal
385 Bradykinesia 8 2.3 2.3 signal
386 Confusional State 222 2.3 2.4 signal
387 Brain Fog 20 2.3 2.3 signal
388 Cardiovascular Disorder 35 2.3 2.3 signal
389 Hypovolaemia 8 2.3 2.3 signal
390 Vomiting 641 2.3 2.4 signal
391 Pulmonary Fibrosis 26 2.3 2.3 signal
392 Poor Venous Access 14 2.3 2.3 signal
393 Speech Disorder 71 2.3 2.3 signal
394 Drug Ineffective 1,773 2.3 2.5 signal
395 Compression Fracture 7 2.3 2.3 no signal
396 Mucosal Inflammation 35 2.3 2.3 signal
397 Blood Lactic Acid Increased 7 2.3 2.3 no signal
398 Postoperative Wound Infection 9 2.3 2.3 signal
399 Vitamin D Deficiency 13 2.3 2.3 signal
400 Dysgeusia 99 2.3 2.3 signal
401 Myocarditis 15 2.3 2.3 signal
402 Hypocalcaemia 25 2.3 2.3 signal
403 Renal Tubular Necrosis 13 2.2 2.3 signal
404 Pneumonia Bacterial 12 2.2 2.2 signal
405 Lymphoedema 9 2.2 2.2 signal
406 Gastroenteritis 19 2.2 2.2 signal
407 Upper Gastrointestinal Haemorrhage 22 2.2 2.2 signal
408 Dysarthria 49 2.2 2.2 signal
409 Haematotoxicity 12 2.2 2.2 signal
410 Pyrexia 448 2.2 2.2 signal
411 Normal Newborn 7 2.2 2.2 no signal
412 Blood Pressure Fluctuation 31 2.2 2.2 signal
413 Gastrointestinal Inflammation 10 2.2 2.2 signal
414 Mouth Ulceration 27 2.2 2.2 signal
415 Neutrophil Count Decreased 52 2.2 2.2 signal
416 Cystitis 41 2.2 2.2 signal
417 Flank Pain 12 2.2 2.2 signal
418 Oesophagitis 14 2.2 2.2 signal
419 Application Site Reaction 9 2.2 2.2 signal
420 Polyneuropathy 15 2.1 2.1 signal
421 Blood Bilirubin Increased 34 2.1 2.1 signal
422 Skin Infection 14 2.1 2.1 signal
423 Screaming 8 2.1 2.1 no signal
424 Head Discomfort 22 2.1 2.1 signal
425 Blood Calcium Decreased 14 2.1 2.1 signal
426 Weight Decreased 346 2.1 2.1 signal
427 Sleep Disorder Due To A General Medical Condition 20 2.1 2.1 signal
428 Choking 24 2.1 2.1 signal
429 Incoherent 8 2.1 2.1 no signal
430 Retching 26 2.1 2.1 signal
431 Oral Discomfort 17 2.1 2.1 signal
432 Pancytopenia 68 2.1 2.1 signal
433 Ileus 15 2.1 2.1 signal
434 Hypertonia 7 2.1 2.1 no signal
435 Hypercalcaemia 15 2.1 2.1 signal
436 Lower Gastrointestinal Haemorrhage 9 2.1 2.1 no signal
437 Neutropenia 164 2.1 2.1 signal
438 Oedema Peripheral 148 2.1 2.1 signal
439 C-reactive Protein Increased 44 2.1 2.1 signal
440 Drug Level Increased 20 2.1 2.1 signal
441 Lung Disorder 59 2.0 2.1 signal
442 Nausea 950 2.0 2.1 signal
443 Hypertriglyceridaemia 7 2.0 2.0 no signal
444 Abdominal Discomfort 200 2.0 2.1 signal
445 Dysuria 44 2.0 2.0 signal
446 Hyperthermia 9 2.0 2.0 no signal
447 Product Taste Abnormal 16 2.0 2.0 signal
448 Brain Oedema 15 2.0 2.0 signal
449 Toxic Skin Eruption 12 2.0 2.0 signal
450 Pseudomonas Infection 10 2.0 2.0 signal
451 Dental Caries 13 2.0 2.0 signal
452 Product Administration Interrupted 9 2.0 2.0 no signal
453 Muscle Rigidity 14 2.0 2.0 no signal
454 Impaired Work Ability 25 2.0 2.0 no signal
455 Musculoskeletal Stiffness 102 2.0 2.0 no signal
456 Generalised Tonic-clonic Seizure 19 2.0 2.0 no signal
457 Hiatus Hernia 15 2.0 2.0 no signal
458 Glomerular Filtration Rate Decreased 14 2.0 2.0 no signal
459 Respiratory Syncytial Virus Infection 10 2.0 2.0 no signal
460 Weight Fluctuation 12 2.0 2.0 no signal
461 Nightmare 40 2.0 2.0 no signal
462 Overdose 249 2.0 2.0 no signal
463 Deep Vein Thrombosis 75 2.0 2.0 no signal
464 Orthostatic Hypotension 20 1.9 2.0 no signal
465 Tumour Lysis Syndrome 10 1.9 1.9 no signal
466 Renal Pain 12 1.9 1.9 no signal
467 Electrolyte Imbalance 13 1.9 1.9 no signal
468 Parkinsonism 11 1.9 1.9 no signal
469 Dehydration 149 1.9 1.9 no signal
470 Cardio-respiratory Arrest 47 1.9 1.9 no signal
471 Wheezing 66 1.9 1.9 no signal
472 Hepatomegaly 11 1.9 1.9 no signal
473 Altered State Of Consciousness 24 1.9 1.9 no signal
474 Muscle Disorder 9 1.9 1.9 no signal
475 Economic Problem 17 1.9 1.9 no signal
476 Blood Iron Decreased 13 1.9 1.9 no signal
477 White Blood Cell Count Abnormal 7 1.9 1.9 no signal
478 Upper-airway Cough Syndrome 9 1.9 1.9 no signal
479 Product Use In Unapproved Indication 268 1.9 1.9 no signal
480 Respiratory Failure 80 1.9 1.9 no signal
481 Neurotoxicity 19 1.9 1.9 no signal
482 Covid-19 Pneumonia 13 1.9 1.9 no signal
483 Anaphylactic Reaction 60 1.9 1.9 no signal
484 Hypomagnesaemia 15 1.8 1.8 no signal
485 Inappropriate Antidiuretic Hormone Secretion 11 1.8 1.8 no signal
486 Appetite Disorder 7 1.8 1.8 no signal
487 Poisoning Deliberate 10 1.8 1.8 no signal
488 Intervertebral Disc Degeneration 10 1.8 1.8 no signal
489 Pneumonitis 29 1.8 1.8 no signal
490 Delirium 37 1.8 1.8 no signal
491 Toxic Epidermal Necrolysis 16 1.8 1.8 no signal
492 Mitral Valve Incompetence 12 1.8 1.8 no signal
493 Tachycardia 94 1.8 1.8 no signal
494 Pulmonary Congestion 14 1.8 1.8 no signal
495 Oxygen Saturation Decreased 59 1.8 1.8 no signal
496 Asthenia 396 1.8 1.8 no signal
497 Drug Hypersensitivity 204 1.8 1.8 no signal
498 Left Ventricular Dysfunction 7 1.8 1.8 no signal
499 Unresponsive To Stimuli 27 1.8 1.8 no signal
500 Haemoglobin Decreased 108 1.8 1.8 no signal
501 Urinary Incontinence 31 1.8 1.8 no signal
502 Seizure 120 1.8 1.8 no signal
503 Blood Magnesium Decreased 9 1.8 1.8 no signal
504 Incontinence 11 1.8 1.8 no signal
505 Bronchopulmonary Aspergillosis 8 1.8 1.8 no signal
506 Haemolysis 8 1.8 1.8 no signal
507 Hypersensitivity 191 1.8 1.8 no signal
508 Pelvic Fracture 8 1.8 1.8 no signal
509 Accidental Exposure To Product By Child 7 1.7 1.7 no signal
510 Respiration Abnormal 7 1.7 1.7 no signal
511 Cytomegalovirus Infection 17 1.7 1.7 no signal
512 Torsade De Pointes 8 1.7 1.7 no signal
513 Covid-19 180 1.7 1.7 no signal
514 Cardiac Arrest 84 1.7 1.7 no signal
515 Pneumonia 327 1.7 1.7 no signal
516 Blood Sodium Decreased 19 1.7 1.7 no signal
517 Large Intestine Polyp 7 1.7 1.7 no signal
518 Large Intestine Perforation 7 1.7 1.7 no signal
519 Mental Status Changes 28 1.7 1.7 no signal
520 Blood Pressure Increased 154 1.7 1.7 no signal
521 Tremor 166 1.7 1.7 no signal
522 Hypotonia 10 1.7 1.7 no signal
523 Coordination Abnormal 14 1.7 1.7 no signal
524 Platelet Count Increased 13 1.7 1.7 no signal
525 Sleep Apnoea Syndrome 19 1.7 1.7 no signal
526 Obsessive-compulsive Disorder 8 1.7 1.7 no signal
527 Pancreatitis Acute 22 1.7 1.7 no signal
528 Rhabdomyolysis 41 1.7 1.7 no signal
529 Accidental Overdose 36 1.7 1.7 no signal
530 Decubitus Ulcer 8 1.7 1.7 no signal
531 Hiccups 8 1.7 1.7 no signal
532 Diverticulitis 27 1.7 1.7 no signal
533 Oral Herpes 19 1.7 1.7 no signal
534 Polyuria 8 1.7 1.7 no signal
535 Urinary Tract Infection 166 1.7 1.7 no signal
536 Lactic Acidosis 31 1.6 1.6 no signal
537 Petechiae 10 1.6 1.6 no signal
538 Pollakiuria 40 1.6 1.6 no signal
539 Tachypnoea 13 1.6 1.6 no signal
540 Myocardial Ischaemia 11 1.6 1.6 no signal
541 Drug Effective For Unapproved Indication 28 1.6 1.6 no signal
542 Extrapyramidal Disorder 24 1.6 1.6 no signal
543 Eye Inflammation 9 1.6 1.6 no signal
544 Oral Disorder 7 1.6 1.6 no signal
545 Neuropathy Peripheral 90 1.6 1.6 no signal
546 Septic Shock 41 1.6 1.6 no signal
547 Liver Disorder 42 1.6 1.6 no signal
548 Hallucination 71 1.6 1.6 no signal
549 Eructation 18 1.6 1.6 no signal
550 Atrial Fibrillation 92 1.6 1.6 no signal
551 Product Communication Issue 8 1.6 1.6 no signal
552 Aggression 47 1.6 1.6 no signal
553 Hip Fracture 30 1.6 1.6 no signal
554 Haemorrhage Intracranial 14 1.6 1.6 no signal
555 Rib Fracture 19 1.6 1.6 no signal
556 Ataxia 11 1.6 1.6 no signal
557 Gastrointestinal Disorder 81 1.6 1.6 no signal
558 Acidosis 7 1.6 1.6 no signal
559 Gastritis 24 1.6 1.6 no signal
560 Thinking Abnormal 17 1.5 1.5 no signal
561 Concussion 7 1.5 1.5 no signal
562 Asthma 101 1.5 1.5 no signal
563 Hepatitis 23 1.5 1.5 no signal
564 Wrong Technique In Product Usage Process 181 1.5 1.5 no signal
565 Eating Disorder 19 1.5 1.5 no signal
566 Metabolic Acidosis 28 1.5 1.5 no signal
567 Sciatica 14 1.5 1.5 no signal
568 Sedation 23 1.5 1.5 no signal
569 Balance Disorder 76 1.5 1.5 no signal
570 Dysphagia 83 1.5 1.5 no signal
571 Systemic Lupus Erythematosus 31 1.5 1.5 no signal
572 Premature Delivery 14 1.5 1.5 no signal
573 Atrial Flutter 7 1.5 1.5 no signal
574 Blood Disorder 7 1.5 1.5 no signal
575 Plasma Cell Myeloma 34 1.5 1.5 no signal
576 Vertigo 53 1.5 1.5 no signal
577 Decreased Appetite 201 1.5 1.5 no signal
578 Hypoglycaemia 42 1.5 1.5 no signal
579 Infusion Site Pain 11 1.5 1.5 no signal
580 Hypertension 182 1.5 1.5 no signal
581 Rhinorrhoea 55 1.5 1.5 no signal
582 Abnormal Behaviour 34 1.4 1.5 no signal
583 No Adverse Event 151 1.4 1.5 no signal
584 Headache 532 1.4 1.5 no signal
585 Heart Rate Increased 84 1.4 1.4 no signal
586 Tinnitus 39 1.4 1.4 no signal
587 Diabetes Mellitus Inadequate Control 15 1.4 1.4 no signal
588 Cholecystitis 10 1.4 1.4 no signal
589 Intentional Dose Omission 23 1.4 1.4 no signal
590 Gastric Ulcer 16 1.4 1.4 no signal
591 Acute Coronary Syndrome 7 1.4 1.4 no signal
592 Fall 278 1.4 1.4 no signal
593 Depressed Level Of Consciousness 33 1.4 1.4 no signal
594 Pharyngeal Swelling 8 1.4 1.4 no signal
595 Subdural Haematoma 12 1.4 1.4 no signal
596 Gait Disturbance 160 1.4 1.4 no signal
597 Electrocardiogram Qt Prolonged 30 1.4 1.4 no signal
598 Blood Urea Increased 14 1.4 1.4 no signal
599 Hernia 16 1.4 1.4 no signal
600 Nervous System Disorder 26 1.4 1.4 no signal
601 Prescribed Overdose 16 1.4 1.4 no signal
602 Ear Pain 16 1.4 1.4 no signal
603 Coma 39 1.4 1.4 no signal
604 Lethargy 47 1.4 1.4 no signal
605 Eye Pain 45 1.4 1.4 no signal
606 Dyskinesia 33 1.4 1.4 no signal
607 Cellulitis 41 1.4 1.4 no signal
608 Bradycardia 43 1.4 1.4 no signal
609 Stomatitis 49 1.4 1.4 no signal
610 Muscle Spasticity 10 1.4 1.4 no signal
611 Disorientation 32 1.4 1.4 no signal
612 Throat Irritation 36 1.4 1.4 no signal
613 Mental Disorder 35 1.4 1.4 no signal
614 Salivary Hypersecretion 8 1.4 1.4 no signal
615 Fistula 9 1.4 1.4 no signal
616 Malaise 351 1.4 1.4 no signal
617 Pharmaceutical Product Complaint 21 1.4 1.4 no signal
618 Disease Recurrence 38 1.4 1.4 no signal
619 Status Epilepticus 9 1.4 1.4 no signal
620 Anger 27 1.4 1.4 no signal
621 Poor Quality Sleep 17 1.4 1.4 no signal
622 Dermatitis Contact 9 1.3 1.3 no signal
623 Chills 93 1.3 1.3 no signal
624 Heart Rate Irregular 18 1.3 1.3 no signal
625 Sluggishness 8 1.3 1.3 no signal
626 Blood Creatine Phosphokinase Increased 23 1.3 1.3 no signal
627 Hypothyroidism 25 1.3 1.3 no signal
628 Dyspnoea 444 1.3 1.3 no signal
629 Leukopenia 39 1.3 1.3 no signal
630 Lip Dry 7 1.3 1.3 no signal
631 Myositis 7 1.3 1.3 no signal
632 White Blood Cell Count Increased 30 1.3 1.3 no signal
633 Extra Dose Administered 31 1.3 1.3 no signal
634 Hyperbilirubinaemia 8 1.3 1.3 no signal
635 Night Sweats 25 1.3 1.3 no signal
636 Folliculitis 8 1.3 1.3 no signal
637 Hyperglycaemia 28 1.3 1.3 no signal
638 Acute Myeloid Leukaemia 12 1.3 1.3 no signal
639 Product Odour Abnormal 8 1.3 1.3 no signal
640 Platelet Count Decreased 82 1.3 1.3 no signal
641 Red Blood Cell Count Decreased 22 1.3 1.3 no signal
642 Neck Pain 43 1.3 1.3 no signal
643 Affective Disorder 6 1.3 1.3 no signal
644 Joint Stiffness 20 1.3 1.3 no signal
645 Blood Thyroid Stimulating Hormone Increased 7 1.3 1.3 no signal
646 White Blood Cell Count Decreased 82 1.3 1.3 no signal
647 Anhedonia 20 1.3 1.3 no signal
648 Hepatic Steatosis 14 1.3 1.3 no signal
649 Muscular Weakness 85 1.3 1.3 no signal
650 Epistaxis 56 1.3 1.3 no signal
651 Decreased Activity 8 1.3 1.3 no signal
652 Dyspnoea Exertional 28 1.3 1.3 no signal
653 Depression 170 1.3 1.3 no signal
654 Acute Myocardial Infarction 22 1.3 1.3 no signal
655 Erythema 152 1.3 1.3 no signal
656 Schizophrenia 9 1.3 1.3 no signal
657 Syncope 74 1.3 1.3 no signal
658 Spinal Disorder 7 1.3 1.3 no signal
659 Product Prescribing Issue 15 1.3 1.3 no signal
660 Arthritis 58 1.3 1.3 no signal
661 Hepatic Enzyme Increased 50 1.3 1.3 no signal
662 Acute Hepatic Failure 10 1.3 1.3 no signal
663 Nasal Congestion 43 1.2 1.2 no signal
664 Bone Marrow Failure 15 1.2 1.2 no signal
665 Alanine Aminotransferase Increased 45 1.2 1.2 no signal
666 Respiratory Tract Infection 19 1.2 1.2 no signal
667 Fatigue 567 1.2 1.3 no signal
668 Photosensitivity Reaction 12 1.2 1.2 no signal
669 Thirst 13 1.2 1.2 no signal
670 Secretion Discharge 9 1.2 1.2 no signal
671 Therapy Change 7 1.2 1.2 no signal
672 Drug Interaction 115 1.2 1.2 no signal
673 Sinus Bradycardia 7 1.2 1.2 no signal
674 Nephrolithiasis 33 1.2 1.2 no signal
675 Epilepsy 22 1.2 1.2 no signal
676 Device Occlusion 10 1.2 1.2 no signal
677 Osteomyelitis 13 1.2 1.2 no signal
678 Haemorrhoids 14 1.2 1.2 no signal
679 Hospitalisation 109 1.2 1.2 no signal
680 Oral Pain 16 1.2 1.2 no signal
681 Carpal Tunnel Syndrome 10 1.2 1.2 no signal
682 Cough 199 1.2 1.2 no signal
683 Back Pain 165 1.2 1.2 no signal
684 Chest Pain 131 1.2 1.2 no signal
685 Dizziness 351 1.2 1.2 no signal
686 Feeding Disorder 14 1.2 1.2 no signal
687 Oedema 38 1.2 1.2 no signal
688 Hypersomnia 20 1.2 1.2 no signal
689 Head Injury 22 1.2 1.2 no signal
690 Therapeutic Response Shortened 22 1.2 1.2 no signal
691 Abscess 11 1.2 1.2 no signal
692 Gastrooesophageal Reflux Disease 55 1.2 1.2 no signal
693 Tooth Abscess 7 1.2 1.2 no signal
694 Metastases To Liver 12 1.2 1.2 no signal
695 Feeling Jittery 13 1.2 1.2 no signal
696 Muscle Tightness 11 1.2 1.2 no signal
697 Euphoric Mood 7 1.2 1.2 no signal
698 Eczema 34 1.1 1.1 no signal
699 Cardiomyopathy 10 1.1 1.1 no signal
700 Sars-cov-2 Test Positive 9 1.1 1.1 no signal
701 Arrhythmia 32 1.1 1.1 no signal
702 Sinusitis 69 1.1 1.1 no signal
703 Quality Of Life Decreased 9 1.1 1.1 no signal
704 Pain 412 1.1 1.1 no signal
705 Cytopenia 8 1.1 1.1 no signal
706 Pulmonary Oedema 30 1.1 1.1 no signal
707 Adrenal Insufficiency 8 1.1 1.1 no signal
708 Rash Papular 15 1.1 1.1 no signal
709 Joint Dislocation 7 1.1 1.1 no signal
710 Staphylococcal Infection 22 1.1 1.1 no signal
711 Chromaturia 15 1.1 1.1 no signal
712 Kidney Infection 13 1.1 1.1 no signal
713 Gastroenteritis Viral 12 1.1 1.1 no signal
714 Premature Baby 20 1.1 1.1 no signal
715 Osteoarthritis 28 1.1 1.1 no signal
716 Restless Legs Syndrome 12 1.1 1.1 no signal
717 Breast Pain 7 1.1 1.1 no signal
718 Product Use Issue 122 1.1 1.1 no signal
719 Spinal Fracture 13 1.1 1.1 no signal
720 Hypoacusis 28 1.1 1.1 no signal
721 Central Nervous System Lesion 9 1.1 1.1 no signal
722 Hot Flush 49 1.1 1.1 no signal
723 Dysstasia 19 1.1 1.1 no signal
724 Device Related Infection 10 1.1 1.1 no signal
725 Wound 18 1.1 1.1 no signal
726 Renal Impairment 54 1.1 1.1 no signal
727 Product Use Complaint 10 1.1 1.1 no signal
728 Anxiety 184 1.1 1.1 no signal
729 Full Blood Count Decreased 13 1.1 1.1 no signal
730 Cyst 8 1.1 1.1 no signal
731 Diarrhoea Haemorrhagic 6 1.1 1.1 no signal
732 Nephropathy 6 1.1 1.1 no signal
733 Disseminated Intravascular Coagulation 9 1.1 1.1 no signal
734 Paranoia 11 1.1 1.1 no signal
735 Tooth Fracture 7 1.1 1.1 no signal
736 Body Temperature Increased 13 1.1 1.1 no signal
737 Pain In Jaw 18 1.1 1.1 no signal
738 Melaena 14 1.1 1.1 no signal
739 Contusion 61 1.1 1.1 no signal
740 Gait Inability 21 1.1 1.1 no signal
741 Blood Pressure Decreased 42 1.1 1.1 no signal
742 Posterior Reversible Encephalopathy Syndrome 6 1.1 1.1 no signal
743 Lower Limb Fracture 12 1.1 1.1 no signal
744 Restlessness 23 1.1 1.1 no signal
745 Aphasia 19 1.1 1.1 no signal
746 Serotonin Syndrome 12 1.1 1.1 no signal
747 Musculoskeletal Pain 33 1.1 1.1 no signal
748 Cognitive Disorder 29 1.1 1.1 no signal
749 Hyperthyroidism 9 1.1 1.1 no signal
750 Pulmonary Arterial Hypertension 9 1.1 1.1 no signal
751 Fibromyalgia 15 1.0 1.0 no signal
752 Illness 62 1.0 1.0 no signal
753 Oropharyngeal Pain 57 1.0 1.0 no signal
754 Peripheral Swelling 94 1.0 1.0 no signal
755 Ligament Sprain 6 1.0 1.0 no signal
756 Tooth Infection 8 1.0 1.0 no signal
757 Blood Pressure Abnormal 12 1.0 1.0 no signal
758 Bronchitis 45 1.0 1.0 no signal
759 Crying 22 1.0 1.0 no signal
760 Rash Macular 21 1.0 1.0 no signal
761 Panic Attack 22 1.0 1.0 no signal
762 Product Physical Issue 12 1.0 1.0 no signal
763 Prescribed Underdose 12 1.0 1.0 no signal
764 Pneumocystis Jirovecii Pneumonia 6 1.0 1.0 no signal
765 Taste Disorder 12 1.0 1.0 no signal
766 Spinal Pain 7 1.0 1.0 no signal
767 Needle Issue 17 1.0 1.0 no signal
768 Motor Dysfunction 6 1.0 1.0 no signal
769 Sinus Congestion 8 1.0 1.0 no signal
770 Initial Insomnia 6 1.0 1.0 no signal
771 Hemiparesis 10 1.0 1.0 no signal
772 Agitation 43 1.0 1.0 no signal
773 Fracture 11 1.0 1.0 no signal
774 Bone Pain 34 1.0 1.0 no signal
775 Foot Fracture 11 1.0 1.0 no signal
776 Spinal Operation 7 1.0 1.0 no signal
777 Discomfort 35 1.0 1.0 no signal
778 Blood Urine Present 11 1.0 1.0 no signal
779 Ventricular Extrasystoles 6 1.0 1.0 no signal
780 Influenza 64 1.0 1.0 no signal
781 Shock 13 1.0 1.0 no signal
782 Loss Of Consciousness 73 1.0 1.0 no signal
783 Pneumothorax 9 1.0 1.0 no signal
784 Maternal Exposure During Pregnancy 50 1.0 1.0 no signal
785 Respiratory Tract Congestion 9 1.0 1.0 no signal
786 Hallucination, Auditory 9 1.0 1.0 no signal
787 Ear Infection 15 1.0 1.0 no signal
788 Pericardial Effusion 13 1.0 1.0 no signal
789 Cardiomegaly 7 1.0 1.0 no signal
790 Hepatocellular Injury 8 1.0 1.0 no signal
791 Sudden Death 6 1.0 1.0 no signal
792 Ageusia 14 1.0 1.0 no signal
793 Malignant Neoplasm Progression 57 1.0 1.0 no signal
794 Cerebrovascular Accident 95 0.9 0.9 no signal
795 Mobility Decreased 40 0.9 0.9 no signal
796 Muscle Atrophy 7 0.9 0.9 no signal
797 Cataract 33 0.9 0.9 no signal
798 International Normalised Ratio Increased 16 0.9 0.9 no signal
799 Pharyngitis Streptococcal 6 0.9 0.9 no signal
800 Haematuria 19 0.9 0.9 no signal
801 Toothache 10 0.9 0.9 no signal
802 Ocular Discomfort 6 0.9 0.9 no signal
803 Treatment Noncompliance 30 0.9 0.9 no signal
804 Weight Increased 122 0.9 0.9 no signal
805 Insomnia 146 0.9 0.9 no signal
806 Metastases To Central Nervous System 7 0.9 0.9 no signal
807 Anaphylactic Shock 14 0.9 0.9 no signal
808 Increased Tendency To Bruise 5 0.9 0.9 no signal
809 Psychotic Disorder 16 0.9 0.9 no signal
810 Product Dose Omission Issue 154 0.9 0.9 no signal
811 Medication Error 30 0.9 0.9 no signal
812 Pericarditis 9 0.9 0.9 no signal
813 Muscle Spasms 99 0.9 0.9 no signal
814 Haematoma 14 0.9 0.9 no signal
815 Acne 41 0.9 0.9 no signal
816 Middle Insomnia 10 0.9 0.9 no signal
817 Bone Density Decreased 17 0.9 0.9 no signal
818 Disturbance In Attention 29 0.9 0.9 no signal
819 Lymphadenopathy 19 0.9 0.9 no signal
820 Renal Disorder 25 0.9 0.9 no signal
821 Osteoporosis 22 0.9 0.9 no signal
822 Respiratory Disorder 16 0.9 0.9 no signal
823 Increased Appetite 10 0.9 0.9 no signal
824 Dermatitis 11 0.9 0.9 no signal
825 Squamous Cell Carcinoma 5 0.9 0.9 no signal
826 Palpitations 62 0.9 0.9 no signal
827 Tooth Loss 11 0.9 0.9 no signal
828 Gastrointestinal Haemorrhage 44 0.9 0.9 no signal
829 Blood Alkaline Phosphatase Increased 13 0.9 0.9 no signal
830 Pain In Extremity 154 0.9 0.9 no signal
831 Angina Pectoris 15 0.9 0.9 no signal
832 Rash Pruritic 28 0.9 0.9 no signal
833 Drug-induced Liver Injury 16 0.9 0.9 no signal
834 Cholelithiasis 17 0.9 0.9 no signal
835 Migraine 49 0.9 0.9 no signal
836 Thrombotic Microangiopathy 5 0.9 0.9 no signal
837 Splenomegaly 6 0.9 0.9 no signal
838 Fluid Retention 26 0.9 0.9 no signal
839 Ill-defined Disorder 31 0.9 0.9 no signal
840 Disease Progression 60 0.9 0.9 no signal
841 Acute Respiratory Distress Syndrome 9 0.9 0.9 no signal
842 Cyanosis 8 0.9 0.9 no signal
843 Prostatic Specific Antigen Increased 7 0.9 0.9 no signal
844 Skin Ulcer 13 0.9 0.9 no signal
845 Cerebral Haemorrhage 18 0.9 0.9 no signal
846 Myoclonus 6 0.9 0.9 no signal
847 Adverse Drug Reaction 45 0.9 0.9 no signal
848 Rash 218 0.9 0.9 no signal
849 Dementia 14 0.9 0.9 no signal
850 Chest Discomfort 51 0.9 0.8 no signal
851 Burning Sensation 35 0.8 0.8 no signal
852 Movement Disorder 16 0.8 0.8 no signal
853 Dry Eye 24 0.8 0.8 no signal
854 Mental Impairment 12 0.8 0.8 no signal
855 Emphysema 5 0.8 0.8 no signal
856 Rash Erythematous 23 0.8 0.8 no signal
857 Metastases To Bone 8 0.8 0.8 no signal
858 Hyperhidrosis 63 0.8 0.8 no signal
859 Herpes Zoster 28 0.8 0.8 no signal
860 Chronic Kidney Disease 37 0.8 0.8 no signal
861 Pemphigus 6 0.8 0.8 no signal
862 Nasopharyngitis 89 0.8 0.8 no signal
863 Apathy 7 0.8 0.8 no signal
864 Dermatitis Allergic 6 0.8 0.8 no signal
865 Viral Infection 16 0.8 0.8 no signal
866 Hypoaesthesia 72 0.8 0.8 no signal
867 Limb Injury 13 0.8 0.8 no signal
868 Psychomotor Hyperactivity 8 0.8 0.8 no signal
869 Pulmonary Hypertension 10 0.8 0.8 no signal
870 Vision Blurred 65 0.8 0.8 no signal
871 Depressed Mood 25 0.8 0.8 no signal
872 Face Oedema 8 0.8 0.8 no signal
873 Haematemesis 12 0.8 0.8 no signal
874 Infection 68 0.8 0.8 no signal
875 Mood Swings 15 0.8 0.8 no signal
876 Drug Reaction With Eosinophilia And Systemic Symptoms 12 0.8 0.8 no signal
877 Rotator Cuff Syndrome 6 0.8 0.8 no signal
878 Hypoaesthesia Oral 7 0.8 0.8 no signal
879 Therapy Partial Responder 7 0.8 0.8 no signal
880 Therapy Interrupted 32 0.8 0.8 no signal
881 Product Dispensing Error 10 0.8 0.8 no signal
882 Bedridden 6 0.8 0.8 no signal
883 Death 393 0.8 0.8 no signal
884 Localised Infection 11 0.8 0.8 no signal
885 Thyroid Disorder 7 0.8 0.8 no signal
886 Pruritus 171 0.8 0.8 no signal
887 Adverse Reaction 6 0.8 0.8 no signal
888 Musculoskeletal Chest Pain 7 0.8 0.8 no signal
889 Arthralgia 186 0.8 0.8 no signal
890 Eye Haemorrhage 6 0.8 0.8 no signal
891 Nerve Injury 5 0.8 0.8 no signal
892 Basal Cell Carcinoma 7 0.8 0.8 no signal
893 Hypertensive Crisis 5 0.8 0.8 no signal
894 Intentional Self-injury 9 0.8 0.8 no signal
895 Pregnancy 9 0.8 0.8 no signal
896 Drug Abuse 37 0.8 0.8 no signal
897 Skin Lesion 12 0.7 0.7 no signal
898 Memory Impairment 60 0.7 0.7 no signal
899 Coronary Artery Occlusion 6 0.7 0.7 no signal
900 Lacrimation Increased 13 0.7 0.7 no signal
901 Sensory Disturbance 7 0.7 0.7 no signal
902 Neoplasm 5 0.7 0.7 no signal
903 Metastases To Lung 5 0.7 0.7 no signal
904 Joint Swelling 52 0.7 0.7 no signal
905 Road Traffic Accident 18 0.7 0.7 no signal
906 Amnesia 28 0.7 0.7 no signal
907 Hepatic Encephalopathy 4 0.7 0.7 no signal
908 Eye Disorder 14 0.7 0.7 no signal
909 Grand Mal Convulsion 4 0.7 0.7 no signal
910 Lymphopenia 6 0.7 0.7 no signal
911 Leukaemia 4 0.7 0.7 no signal
912 Irritable Bowel Syndrome 9 0.7 0.7 no signal
913 Nervousness 22 0.7 0.7 no signal
914 Skin Cancer 9 0.7 0.7 no signal
915 Product Substitution Issue 24 0.7 0.7 no signal
916 Affect Lability 4 0.7 0.7 no signal
917 Dystonia 8 0.7 0.7 no signal
918 Vitreous Floaters 4 0.7 0.7 no signal
919 Musculoskeletal Discomfort 7 0.7 0.7 no signal
920 Inability To Afford Medication 4 0.7 0.7 no signal
921 Ocular Hyperaemia 19 0.7 0.7 no signal
922 Hepatotoxicity 9 0.7 0.7 no signal
923 Fear 11 0.7 0.7 no signal
924 Mood Altered 11 0.7 0.7 no signal
925 Therapy Non-responder 18 0.7 0.7 no signal
926 Abnormal Weight Gain 5 0.7 0.7 no signal
927 Peritonitis Bacterial 4 0.7 0.7 no signal
928 Renal Failure 53 0.7 0.7 no signal
929 Device Failure 6 0.7 0.7 no signal
930 Hip Arthroplasty 6 0.7 0.7 no signal
931 Blood Triglycerides Increased 7 0.7 0.7 no signal
932 Dry Throat 4 0.7 0.7 no signal
933 Skin Discolouration 18 0.7 0.7 no signal
934 Gallbladder Disorder 7 0.7 0.7 no signal
935 Ear Discomfort 4 0.7 0.7 no signal
936 Mydriasis 5 0.7 0.7 no signal
937 Myalgia 66 0.7 0.7 no signal
938 Pelvic Pain 7 0.7 0.7 no signal
939 Foetal Exposure During Pregnancy 31 0.6 0.6 no signal
940 Immune System Disorder 5 0.6 0.6 no signal
941 Surgery 22 0.6 0.6 no signal
942 Therapeutic Response Unexpected 17 0.6 0.6 no signal
943 Blood Glucose Decreased 18 0.6 0.6 no signal
944 Cardiac Failure 30 0.6 0.6 no signal
945 Body Height Decreased 4 0.6 0.6 no signal
946 Cardiac Failure Congestive 30 0.6 0.6 no signal
947 Musculoskeletal Disorder 7 0.6 0.6 no signal
948 Impaired Healing 12 0.6 0.6 no signal
949 Urticaria 60 0.6 0.6 no signal
950 Amenorrhoea 6 0.6 0.6 no signal
951 Pancreatitis 19 0.6 0.6 no signal
952 Eye Irritation 20 0.6 0.6 no signal
953 Tooth Disorder 8 0.6 0.6 no signal
954 Limb Discomfort 11 0.6 0.6 no signal
955 Muscle Twitching 8 0.6 0.6 no signal
956 Unevaluable Event 26 0.6 0.6 no signal
957 Deafness 9 0.6 0.6 no signal
958 Flushing 35 0.6 0.6 no signal
959 Post Procedural Haemorrhage 4 0.6 0.6 no signal
960 Palmar-plantar Erythrodysaesthesia Syndrome 8 0.6 0.6 no signal
961 Feeling Abnormal 82 0.6 0.6 no signal
962 Meningioma 5 0.6 0.6 no signal
963 Laboratory Test Abnormal 10 0.6 0.6 no signal
964 Suicidal Ideation 31 0.6 0.6 no signal
965 Product Dose Omission In Error 9 0.6 0.6 no signal
966 Product Dose Omission 22 0.6 0.6 no signal
967 Drug Dependence 54 0.6 0.6 no signal
968 Withdrawal Syndrome 14 0.6 0.6 no signal
969 Hepatic Failure 10 0.6 0.6 no signal
970 Skin Disorder 11 0.6 0.6 no signal
971 Pallor 9 0.6 0.6 no signal
972 Paraesthesia 52 0.6 0.6 no signal
973 Cerebral Infarction 8 0.6 0.6 no signal
974 Gastrointestinal Carcinoma 3 0.6 0.6 no signal
975 Brain Neoplasm 3 0.6 0.6 no signal
976 Blood Count Abnormal 5 0.6 0.6 no signal
977 No Therapeutic Response 4 0.5 0.5 no signal
978 Psoriatic Arthropathy 13 0.5 0.5 no signal
979 Lymphoma 5 0.5 0.5 no signal
980 Femur Fracture 10 0.5 0.5 no signal
981 Tooth Extraction 4 0.5 0.5 no signal
982 Personality Change 3 0.5 0.5 no signal
983 Skin Fissures 6 0.5 0.5 no signal
984 Glycosylated Haemoglobin Increased 8 0.5 0.5 no signal
985 Poisoning 4 0.5 0.5 no signal
986 Injection Site Irritation 4 0.5 0.5 no signal
987 Gastric Disorder 11 0.5 0.5 no signal
988 Stevens-johnson Syndrome 7 0.5 0.5 no signal
989 Blood Glucose Increased 59 0.5 0.5 no signal
990 Feeling Hot 19 0.5 0.5 no signal
991 Ankylosing Spondylitis 4 0.5 0.5 no signal
992 Dysmenorrhoea 4 0.5 0.5 no signal
993 Arthropathy 17 0.5 0.5 no signal
994 Mania 5 0.5 0.5 no signal
995 Eye Pruritus 10 0.5 0.5 no signal
996 Lip Swelling 10 0.5 0.5 no signal
997 Visual Impairment 37 0.5 0.5 no signal
998 Visual Acuity Reduced 10 0.5 0.5 no signal
999 Drug Effect Incomplete 11 0.5 0.5 no signal
1000 Haemorrhage 31 0.5 0.5 no signal
1001 Jaundice 8 0.5 0.5 no signal
1002 Suicide Attempt 18 0.5 0.5 no signal
1003 Throat Tightness 8 0.5 0.5 no signal
1004 Uveitis 4 0.5 0.5 no signal
1005 Alopecia 58 0.5 0.5 no signal
1006 Inflammation 15 0.5 0.5 no signal
1007 Liver Injury 7 0.5 0.5 no signal
1008 Emotional Distress 35 0.5 0.5 no signal
1009 Knee Arthroplasty 6 0.5 0.5 no signal
1010 Skeletal Injury 3 0.5 0.5 no signal
1011 Toxicity To Various Agents 48 0.5 0.5 no signal
1012 Neoplasm Progression 10 0.5 0.5 no signal
1013 Adverse Event 26 0.5 0.5 no signal
1014 Myelodysplastic Syndrome 4 0.5 0.5 no signal
1015 Anosmia 4 0.5 0.5 no signal
1016 Dry Skin 36 0.5 0.5 no signal
1017 Blood Glucose Fluctuation 3 0.5 0.5 no signal
1018 Eye Swelling 10 0.5 0.5 no signal
1019 Multiple Sclerosis 13 0.5 0.5 no signal
1020 Irritability 16 0.5 0.5 no signal
1021 Myelosuppression 9 0.4 0.4 no signal
1022 Internal Haemorrhage 3 0.4 0.4 no signal
1023 Drug Withdrawal Syndrome 23 0.4 0.4 no signal
1024 Influenza Like Illness 21 0.4 0.4 no signal
1025 Intentional Overdose 16 0.4 0.4 no signal
1026 Blister 14 0.4 0.4 no signal
1027 Cardiac Disorder 23 0.4 0.4 no signal
1028 Injection Site Mass 9 0.4 0.4 no signal
1029 Multiple Fractures 4 0.4 0.4 no signal
1030 Injury 17 0.4 0.4 no signal
1031 Liver Function Test Abnormal 7 0.4 0.4 no signal
1032 Therapeutic Response Decreased 14 0.4 0.4 no signal
1033 Complication Associated With Device 3 0.4 0.4 no signal
1034 Menstruation Irregular 6 0.4 0.4 no signal
1035 Emotional Disorder 7 0.4 0.4 no signal
1036 Pain Of Skin 6 0.4 0.4 no signal
1037 Akathisia 3 0.4 0.4 no signal
1038 Device Issue 19 0.4 0.4 no signal
1039 Skin Exfoliation 18 0.4 0.4 no signal
1040 Blood Glucose Abnormal 4 0.4 0.4 no signal
1041 Vaginal Haemorrhage 9 0.4 0.4 no signal
1042 Tardive Dyskinesia 6 0.4 0.4 no signal
1043 Fungal Infection 7 0.4 0.4 no signal
1044 Diabetic Ketoacidosis 5 0.4 0.4 no signal
1045 Interstitial Lung Disease 10 0.4 0.4 no signal
1046 Osteonecrosis Of Jaw 5 0.3 0.3 no signal
1047 Bone Loss 3 0.3 0.3 no signal
1048 Blindness 8 0.3 0.3 no signal
1049 Rheumatoid Arthritis 22 0.3 0.3 no signal
1050 Drug Dispensing Error 3 0.3 0.3 no signal
1051 Incorrect Route Of Drug Administration 7 0.3 0.3 no signal
1052 Exposure During Pregnancy 12 0.3 0.3 no signal
1053 Psoriasis 25 0.3 0.3 no signal
1054 Device Defective 3 0.3 0.3 no signal
1055 Skin Irritation 8 0.3 0.3 no signal
1056 Treatment Failure 14 0.3 0.3 no signal
1057 Device Dislocation 7 0.3 0.3 no signal
1058 Multiple Sclerosis Relapse 11 0.3 0.3 no signal
1059 Injection Site Swelling 12 0.3 0.3 no signal
1060 Therapy Cessation 8 0.3 0.3 no signal
1061 Product Quality Issue 21 0.3 0.3 no signal
1062 Device Breakage 6 0.3 0.3 no signal
1063 Injection Site Haemorrhage 12 0.3 0.3 no signal
1064 Product Preparation Error 3 0.2 0.2 no signal
1065 Device Leakage 6 0.2 0.2 no signal
1066 Accidental Exposure To Product 14 0.2 0.2 no signal
1067 Dermatitis Atopic 7 0.2 0.2 no signal
1068 Breast Cancer 13 0.2 0.2 no signal
1069 Myocardial Infarction 24 0.2 0.2 no signal
1070 Exposure Via Skin Contact 3 0.2 0.2 no signal
1071 Injection Site Rash 4 0.2 0.2 no signal
1072 Drug Dose Omission 21 0.2 0.2 no signal
1073 Renal Cancer 6 0.2 0.2 no signal
1074 Convulsion 7 0.2 0.2 no signal
1075 Injection Site Pruritus 8 0.2 0.2 no signal
1076 Bladder Cancer 7 0.2 0.2 no signal
1077 Gastric Cancer 3 0.2 0.2 no signal
1078 Injection Site Erythema 14 0.2 0.2 no signal
1079 Breast Cancer Female 3 0.2 0.2 no signal
1080 Dependence 6 0.2 0.2 no signal
1081 Neoplasm Malignant 7 0.2 0.2 no signal
1082 Injection Site Pain 29 0.2 0.2 no signal
1083 Prostate Cancer 7 0.1 0.1 no signal