OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Mercaptopurine

1,147 flagged reaction(s) · 63,989 total co-reports · max PRR 2,687.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Human Bocavirus Infection 130 2,687.9 2,708.3 signal
2 Hcov-hku1 Infection 11 1,319.1 1,320.0 signal
3 Lymphoid Tissue Hypoplasia 77 1,319.1 1,325.0 signal
4 Thymus Hypoplasia 82 1,117.4 1,122.8 signal
5 Picornavirus Infection 14 699.5 700.1 signal
6 Occupational Asthma 19 584.2 584.9 signal
7 Perineal Necrosis 13 577.4 577.8 signal
8 Cystitis Bacterial 107 560.3 563.8 signal
9 Norovirus Test Positive 100 545.1 548.3 signal
10 Mycobacterium Chelonae Infection 165 352.1 355.5 signal
11 Secondary Immunodeficiency 244 312.9 317.4 signal
12 Hepatosplenic T-cell Lymphoma 71 286.7 287.9 signal
13 Abscess Bacterial 68 286.1 287.3 signal
14 Fibrinous Bronchitis 14 284.6 284.8 signal
15 Enterovirus Test Positive 26 213.6 213.9 signal
16 Corona Virus Infection 62 202.0 202.8 signal
17 Treatment Related Secondary Malignancy 24 160.8 161.0 signal
18 Parainfluenzae Virus Infection 169 149.1 150.6 signal
19 Glioma 66 139.6 140.1 signal
20 Central Hypothyroidism 31 135.7 135.9 signal
21 Pseudomonal Sepsis 175 134.2 135.5 signal
22 Eosinophilic Pneumonia Chronic 27 119.9 120.1 signal
23 Human Herpesvirus 6 Infection 163 113.8 114.9 signal
24 Bacterial Vulvovaginitis 24 111.6 111.7 signal
25 Eosinophilic Bronchitis 17 111.4 111.5 signal
26 Enterobacter Infection 138 108.9 109.8 signal
27 Human Rhinovirus Test Positive 29 102.6 102.8 signal
28 Temporal Lobe Epilepsy 34 101.7 101.9 signal
29 Cytomegalovirus Chorioretinitis 134 90.8 91.5 signal
30 Viraemia 96 90.1 90.6 signal
31 Disseminated Aspergillosis 32 89.0 89.2 signal
32 Perineal Infection 13 84.3 84.3 signal
33 Diffuse Alveolar Damage 72 80.9 81.3 signal
34 T-cell Type Acute Leukaemia 12 75.3 75.4 signal
35 Enterovirus Infection 47 70.7 70.9 signal
36 Rhinovirus Infection 202 68.3 69.1 signal
37 Bacillus Infection 33 67.8 67.9 signal
38 Glioblastoma Multiforme 44 66.5 66.7 signal
39 Ileocaecal Resection 17 65.6 65.6 signal
40 Pneumatosis Intestinalis 142 64.0 64.5 signal
41 Acute Lymphocytic Leukaemia Recurrent 129 63.9 64.4 signal
42 Oesophageal Dilatation 21 61.4 61.5 signal
43 Antithrombin Iii Decreased 12 57.1 57.1 signal
44 Bile Acid Malabsorption 12 55.8 55.8 signal
45 Vital Capacity Decreased 19 53.5 53.5 signal
46 Lentigo 21 53.5 53.5 signal
47 Nodular Regenerative Hyperplasia 29 51.7 51.8 signal
48 Angiocentric Lymphoma 20 50.9 51.0 signal
49 Trichodysplasia Spinulosa 15 50.4 50.4 signal
50 Venoocclusive Liver Disease 189 48.6 49.1 signal
51 Gastroenteritis Norovirus 51 48.3 48.4 signal
52 Leukaemia Recurrent 64 47.8 48.0 signal
53 Gallbladder Oedema 11 47.3 47.3 signal
54 Cytomegalovirus Gastrointestinal Infection 11 46.3 46.3 signal
55 Enterobacter Bacteraemia 11 46.0 46.0 signal
56 Anaemia Megaloblastic 16 45.7 45.7 signal
57 Molluscum Contagiosum 19 44.9 44.9 signal
58 Otitis Media Acute 26 44.5 44.5 signal
59 Caecitis 16 44.2 44.3 signal
60 Female Sterilisation 18 44.1 44.1 signal
61 Drug Clearance Decreased 44 44.0 44.1 signal
62 Myelodysplastic Syndrome Transformation 18 43.1 43.1 signal
63 Haemophilus Infection 33 42.7 42.8 signal
64 Crohn's Disease 232 42.0 42.5 signal
65 Central Obesity 24 41.2 41.2 signal
66 Cytomegalovirus Hepatitis 11 39.0 39.1 signal
67 Pseudomonal Bacteraemia 25 37.3 37.4 signal
68 Febrile Neutropenia 1,903 36.0 40.3 signal
69 Cytomegalovirus Viraemia 125 35.7 36.0 signal
70 Chloroma 12 35.5 35.6 signal
71 Lower Respiratory Tract Infection Fungal 11 35.0 35.0 signal
72 Minimal Residual Disease 13 34.6 34.7 signal
73 Enteritis 172 33.8 34.2 signal
74 Faecal Calprotectin Abnormal 11 33.7 33.8 signal
75 Gastrointestinal Wall Thickening 40 33.6 33.7 signal
76 Venoocclusive Disease 66 32.9 33.0 signal
77 Epstein Barr Virus Positive Mucocutaneous Ulcer 13 32.5 32.6 signal
78 Leukoencephalopathy 97 32.3 32.5 signal
79 Intestinal Anastomosis 16 31.8 31.8 signal
80 Pulmonary Mucormycosis 13 31.4 31.5 signal
81 Oesophageal Candidiasis 99 31.2 31.4 signal
82 Bronchopulmonary Aspergillosis 193 31.2 31.5 signal
83 Aspergillus Infection 160 30.7 31.0 signal
84 Clostridium Difficile Colitis 262 30.7 31.2 signal
85 Scedosporium Infection 17 30.6 30.6 signal
86 Pancreatic Pseudocyst 19 30.4 30.5 signal
87 Histoplasmosis Disseminated 38 30.4 30.4 signal
88 Venous Thrombosis 96 30.4 30.5 signal
89 Pseudomonas Test Positive 20 30.2 30.2 signal
90 Abdominal Compartment Syndrome 15 30.0 30.0 signal
91 Febrile Bone Marrow Aplasia 96 28.5 28.7 signal
92 Histiocytosis Haematophagic 69 28.5 28.6 signal
93 Drug Level Abnormal 12 28.2 28.2 signal
94 Ileal Stenosis 40 28.0 28.0 signal
95 Superior Sagittal Sinus Thrombosis 18 27.7 27.7 signal
96 Epstein-barr Virus Associated Lymphoma 13 27.4 27.4 signal
97 Epstein-barr Virus Associated Lymphoproliferative Disorder 39 27.4 27.4 signal
98 Perirectal Abscess 24 26.7 26.7 signal
99 Hypertriglyceridaemia 125 26.6 26.8 signal
100 Respiratory Syncytial Virus Test Positive 15 26.4 26.4 signal
101 Cytogenetic Abnormality 24 26.3 26.3 signal
102 Mucormycosis 53 25.5 25.6 signal
103 Enterocolitis Infectious 19 25.3 25.4 signal
104 Bacterial Infection 379 25.3 25.9 signal
105 Rhonchi 28 25.1 25.1 signal
106 Terminal Ileitis 12 24.7 24.7 signal
107 Cardiac Ventricular Thrombosis 25 24.5 24.6 signal
108 Intracardiac Thrombus 61 24.3 24.4 signal
109 Cerebral Venous Sinus Thrombosis 16 24.2 24.2 signal
110 Myelopathy 37 24.1 24.1 signal
111 Blood Culture Positive 58 23.7 23.8 signal
112 Blood Fibrinogen Decreased 21 23.2 23.2 signal
113 Vascular Access Complication 15 22.9 23.0 signal
114 Metapneumovirus Infection 14 22.8 22.9 signal
115 Acute Lymphocytic Leukaemia 50 21.8 21.9 signal
116 Haematotoxicity 163 21.8 21.9 signal
117 T-cell Lymphoma 20 21.7 21.7 signal
118 Stress Urinary Incontinence 19 21.6 21.7 signal
119 Escherichia Test Positive 21 21.6 21.7 signal
120 Neutropenic Colitis 36 21.6 21.7 signal
121 Tracheitis 13 21.2 21.2 signal
122 Histoplasmosis 30 20.9 20.9 signal
123 Klebsiella Test Positive 11 20.8 20.9 signal
124 Intracranial Venous Sinus Thrombosis 18 20.5 20.5 signal
125 Pneumonia Fungal 64 20.4 20.5 signal
126 Sinusitis Fungal 13 20.4 20.4 signal
127 Cushingoid 53 20.3 20.3 signal
128 Pouchitis 14 20.1 20.1 signal
129 Klebsiella Sepsis 18 19.7 19.7 signal
130 Peripheral Motor Neuropathy 22 19.5 19.5 signal
131 Stenotrophomonas Infection 21 19.4 19.4 signal
132 Reversible Posterior Leukoencephalopathy Syndrome 12 18.7 18.7 signal
133 Rectal Abscess 25 18.3 18.4 signal
134 Gallbladder Enlargement 15 17.4 17.4 signal
135 Klebsiella Bacteraemia 13 17.2 17.2 signal
136 Escherichia Bacteraemia 32 17.0 17.1 signal
137 Acute Promyelocytic Leukaemia 14 16.9 16.9 signal
138 Hyperbilirubinaemia 141 16.9 17.0 signal
139 Chronic Hepatitis 11 16.8 16.8 signal
140 Intestinal Dilatation 18 16.7 16.8 signal
141 Epidermal Necrosis 13 16.3 16.3 signal
142 Small Intestinal Stenosis 14 16.2 16.2 signal
143 Systemic Mycosis 15 15.8 15.8 signal
144 Clostridium Test Positive 28 15.8 15.8 signal
145 Cytomegalovirus Colitis 29 15.8 15.8 signal
146 Fistula Discharge 16 15.5 15.5 signal
147 Aplasia 25 15.4 15.4 signal
148 Strongyloidiasis 20 15.2 15.2 signal
149 Bilirubin Conjugated Increased 28 14.8 14.8 signal
150 Neoplasm Recurrence 40 14.5 14.5 signal
151 Hypofibrinogenaemia 11 13.9 14.0 signal
152 B-cell Lymphoma 38 13.7 13.7 signal
153 Herpes Simplex 72 13.6 13.7 signal
154 Proctitis 31 13.6 13.6 signal
155 Lung Opacity 28 13.4 13.4 signal
156 Multiple-drug Resistance 33 13.1 13.1 signal
157 Hepatotoxicity 236 13.1 13.2 signal
158 Large Intestinal Stenosis 21 13.0 13.1 signal
159 Myelosuppression 361 13.0 13.3 signal
160 Acute Myeloid Leukaemia 164 12.9 13.1 signal
161 Female Genital Tract Fistula 18 12.8 12.9 signal
162 Anal Abscess 56 12.8 12.8 signal
163 Neurotoxicity 181 12.8 12.9 signal
164 Drug Specific Antibody Present 67 12.7 12.7 signal
165 Nasal Septum Deviation 20 12.6 12.6 signal
166 Jugular Vein Thrombosis 18 12.5 12.5 signal
167 Pancreatitis Necrotising 23 12.4 12.4 signal
168 Epstein-barr Viraemia 11 12.4 12.4 signal
169 Portal Hypertension 31 12.3 12.3 signal
170 Vocal Cord Paralysis 18 12.3 12.3 signal
171 Listeriosis 11 12.3 12.3 signal
172 Anal Fistula 53 12.2 12.2 signal
173 Soft Tissue Infection 18 12.2 12.2 signal
174 Intestinal Fistula 14 12.2 12.2 signal
175 Staphylococcal Sepsis 49 12.1 12.2 signal
176 Second Primary Malignancy 82 12.1 12.2 signal
177 Haemolytic Uraemic Syndrome 23 12.0 12.0 signal
178 Abscess Intestinal 21 11.9 11.9 signal
179 Hepatosplenomegaly 25 11.9 11.9 signal
180 Escherichia Infection 79 11.9 11.9 signal
181 Chronic Sinusitis 36 11.8 11.8 signal
182 Encephalitis 66 11.7 11.8 signal
183 Pneumocystis Jirovecii Infection 11 11.7 11.7 signal
184 Viral Infection 314 11.6 11.8 signal
185 Myelodysplastic Syndrome 135 11.4 11.5 signal
186 Systemic Candida 23 11.4 11.4 signal
187 Pneumonia Klebsiella 17 11.4 11.4 signal
188 Bacterial Sepsis 30 11.3 11.3 signal
189 Hypoalbuminaemia 70 11.2 11.3 signal
190 Non-hodgkin's Lymphoma 12 11.1 11.1 signal
191 Epstein-barr Virus Infection 56 11.0 11.1 signal
192 Staphylococcus Test Positive 19 11.0 11.0 signal
193 Hepatitis E 14 10.9 10.9 signal
194 Painful Respiration 21 10.7 10.7 signal
195 Superinfection 13 10.6 10.6 signal
196 Bone Marrow Failure 177 10.6 10.7 signal
197 Escherichia Sepsis 25 10.6 10.6 signal
198 Staphylococcal Bacteraemia 37 10.5 10.5 signal
199 Pneumonia Viral 27 10.4 10.4 signal
200 Pneumocystis Jiroveci Pneumonia 19 10.3 10.3 signal
201 Proctalgia 54 10.3 10.3 signal
202 Colectomy 47 10.3 10.3 signal
203 Klebsiella Infection 42 10.2 10.3 signal
204 Faecal Calprotectin Increased 26 10.2 10.2 signal
205 Gastrointestinal Stoma Complication 13 10.2 10.2 signal
206 Aspergillosis 11 10.2 10.2 signal
207 Erythema Nodosum 29 10.1 10.2 signal
208 Steroid Diabetes 12 10.1 10.1 signal
209 Mucosal Inflammation 214 10.1 10.2 signal
210 Haemophagocytic Lymphohistiocytosis 59 10.0 10.0 signal
211 Otitis Media 27 10.0 10.0 signal
212 Nuclear Magnetic Resonance Imaging Brain Abnormal 12 10.0 10.0 signal
213 Meningitis Cryptococcal 14 9.9 9.9 signal
214 Intracranial Pressure Increased 45 9.9 9.9 signal
215 Adenovirus Infection 23 9.8 9.8 signal
216 Intestinal Stenosis 33 9.6 9.6 signal
217 Bronchitis Chronic 19 9.5 9.5 signal
218 Pancytopenia 427 9.4 9.6 signal
219 Pancreatitis Acute 170 9.3 9.4 signal
220 Abdominal Adhesions 24 9.3 9.3 signal
221 Lymphopenia 106 9.2 9.3 signal
222 Ileostomy 19 9.2 9.2 signal
223 Pneumocystis Jirovecii Pneumonia 75 9.2 9.2 signal
224 Colitis Ulcerative 331 9.1 9.2 signal
225 Enterocolitis Haemorrhagic 11 9.1 9.1 signal
226 Lung Infiltration 64 8.8 8.8 signal
227 Activated Partial Thromboplastin Time Prolonged 36 8.7 8.7 signal
228 Hypertransaminasaemia 48 8.6 8.6 signal
229 Hepatic Fibrosis 24 8.6 8.6 signal
230 Blood Immunoglobulin G Decreased 17 8.5 8.5 signal
231 Anal Fissure 37 8.5 8.5 signal
232 Gastrointestinal Oedema 12 8.3 8.3 signal
233 Cytomegalovirus Infection Reactivation 29 8.3 8.3 signal
234 Cholangitis Sclerosing 14 8.3 8.3 signal
235 Pneumonia Cytomegaloviral 13 8.3 8.3 signal
236 Lung Consolidation 19 8.3 8.3 signal
237 Fistula 76 8.3 8.3 signal
238 Coagulopathy 112 8.2 8.3 signal
239 Atrial Thrombosis 14 8.2 8.2 signal
240 Neutrophil Count Abnormal 19 8.2 8.2 signal
241 Small Intestinal Obstruction 82 8.2 8.2 signal
242 Large Intestinal Ulcer 18 8.1 8.2 signal
243 Pulmonary Haemorrhage 52 8.1 8.2 signal
244 Panniculitis 16 8.1 8.1 signal
245 Drug Level Above Therapeutic 30 8.1 8.1 signal
246 Oral Herpes 128 8.1 8.1 signal
247 Cerebral Venous Thrombosis 12 8.0 8.1 signal
248 Abscess Limb 28 8.0 8.0 signal
249 Enterocolitis 37 7.9 7.9 signal
250 Stem Cell Transplant 16 7.9 7.9 signal
251 Glossitis 23 7.9 7.9 signal
252 Stenosis 12 7.9 7.9 signal
253 Diffuse Large B-cell Lymphoma 49 7.9 7.9 signal
254 Partial Seizures 33 7.8 7.8 signal
255 Functional Gastrointestinal Disorder 22 7.8 7.8 signal
256 Areflexia 17 7.7 7.7 signal
257 Bacterial Test Positive 14 7.7 7.7 signal
258 Embolism Venous 19 7.7 7.7 signal
259 Skin Papilloma 25 7.6 7.6 signal
260 Cytomegalovirus Test Positive 11 7.6 7.6 signal
261 Cardiotoxicity 55 7.6 7.6 signal
262 Bacteraemia 73 7.6 7.6 signal
263 Colitis 233 7.6 7.7 signal
264 Paraparesis 11 7.5 7.5 signal
265 Pseudomonas Infection 52 7.5 7.5 signal
266 Anaemia Macrocytic 13 7.5 7.5 signal
267 Lymphoproliferative Disorder 18 7.5 7.5 signal
268 Cytopenia 73 7.5 7.5 signal
269 Methaemoglobinaemia 14 7.4 7.4 signal
270 Lipase Increased 46 7.4 7.4 signal
271 Blood Bilirubin Increased 162 7.3 7.4 signal
272 Clostridial Infection 20 7.2 7.2 signal
273 Acute Graft Versus Host Disease In Skin 16 7.1 7.1 signal
274 Osteonecrosis 192 7.1 7.1 signal
275 Diarrhoea Haemorrhagic 54 7.0 7.1 signal
276 Body Temperature Fluctuation 12 7.0 7.0 signal
277 Posterior Reversible Encephalopathy Syndrome 54 6.9 7.0 signal
278 Nasal Polyps 27 6.8 6.8 signal
279 Fungal Infection 186 6.8 6.9 signal
280 Paraplegia 16 6.8 6.8 signal
281 Cytomegalovirus Infection 92 6.8 6.8 signal
282 Injection Site Papule 25 6.8 6.8 signal
283 Sputum Discoloured 52 6.7 6.7 signal
284 Facial Palsy 12 6.7 6.7 signal
285 Respiratory Syncytial Virus Infection 47 6.6 6.6 signal
286 Gastrointestinal Inflammation 42 6.6 6.6 signal
287 Coronavirus Infection 36 6.6 6.6 signal
288 Ocular Icterus 23 6.5 6.5 signal
289 Malnutrition 59 6.5 6.5 signal
290 Pancreatitis 281 6.5 6.6 signal
291 Loss Of Therapeutic Response 16 6.5 6.5 signal
292 Appendicitis 48 6.3 6.3 signal
293 Type Iv Hypersensitivity Reaction 14 6.3 6.3 signal
294 Peripheral Sensory Neuropathy 30 6.3 6.3 signal
295 Neutrophil Count Decreased 207 6.2 6.3 signal
296 Drug Level Decreased 52 6.2 6.2 signal
297 Serum Sickness 14 6.1 6.2 signal
298 Blood Lactic Acid Increased 26 6.1 6.1 signal
299 Aplastic Anaemia 26 6.1 6.1 signal
300 Splenomegaly 58 6.0 6.1 signal
301 Drug Level Below Therapeutic 27 6.0 6.0 signal
302 Device Related Infection 75 5.9 6.0 signal
303 Melanocytic Naevus 21 5.8 5.9 signal
304 Facial Paresis 17 5.8 5.8 signal
305 Rhinitis 38 5.8 5.8 signal
306 Nocardiosis 12 5.7 5.7 signal
307 Septic Shock 202 5.7 5.8 signal
308 Respiratory Distress 129 5.7 5.7 signal
309 Lupus-like Syndrome 42 5.7 5.7 signal
310 Bone Marrow Disorder 14 5.7 5.7 signal
311 Amylase Increased 17 5.7 5.7 signal
312 Hepatic Steatosis 86 5.6 5.7 signal
313 Hyperammonaemia 23 5.6 5.6 signal
314 Clostridium Difficile Infection 99 5.6 5.6 signal
315 Enterococcal Infection 22 5.5 5.6 signal
316 Polyneuropathy 54 5.5 5.6 signal
317 Hypogammaglobulinaemia 29 5.5 5.5 signal
318 Frequent Bowel Movements 121 5.5 5.5 signal
319 Meningitis 30 5.5 5.5 signal
320 Abdominal Tenderness 22 5.4 5.4 signal
321 Furuncle 35 5.4 5.4 signal
322 Acute Respiratory Distress Syndrome 78 5.4 5.4 signal
323 Multiple Organ Dysfunction Syndrome 123 5.4 5.4 signal
324 Sepsis 491 5.4 5.5 signal
325 Neutropenia 596 5.4 5.5 signal
326 Hemiparesis 74 5.3 5.3 signal
327 Alanine Aminotransferase Increased 266 5.3 5.4 signal
328 Abdominal Abscess 19 5.2 5.3 signal
329 Viith Nerve Paralysis 15 5.2 5.2 signal
330 Transaminases Increased 95 5.2 5.2 signal
331 Inflammatory Bowel Disease 42 5.2 5.2 signal
332 Atelectasis 41 5.2 5.2 signal
333 Candidiasis 17 5.1 5.1 signal
334 Subcutaneous Abscess 20 5.1 5.1 signal
335 Therapeutic Reaction Time Decreased 12 5.0 5.0 signal
336 Hypophagia 103 5.0 5.0 signal
337 Ileus Paralytic 18 4.9 4.9 signal
338 Iron Deficiency 18 4.9 4.9 signal
339 Cellulitis 204 4.9 5.0 signal
340 Squamous Cell Carcinoma Of Skin 24 4.9 4.9 signal
341 Cholestasis 76 4.9 4.9 signal
342 Prothrombin Time Prolonged 24 4.8 4.8 signal
343 Hepatomegaly 39 4.8 4.8 signal
344 Skin Toxicity 22 4.8 4.8 signal
345 Demyelination 16 4.7 4.7 signal
346 Thrombocytosis 14 4.7 4.7 signal
347 Leukopenia 191 4.7 4.7 signal
348 Post Transplant Lymphoproliferative Disorder 19 4.6 4.6 signal
349 Hepatitis B Reactivation 12 4.6 4.6 signal
350 Facial Paralysis 32 4.6 4.6 signal
351 Defaecation Urgency 26 4.5 4.6 signal
352 Odynophagia 22 4.5 4.5 signal
353 Hydrocephalus 20 4.5 4.5 signal
354 Potentiating Drug Interaction 12 4.5 4.5 signal
355 Appendicectomy 13 4.5 4.5 signal
356 Multi-organ Failure 64 4.4 4.5 signal
357 Pyoderma Gangrenosum 13 4.4 4.4 signal
358 Encephalopathy 89 4.4 4.4 signal
359 Tachypnoea 49 4.4 4.4 signal
360 Cholangitis 22 4.4 4.4 signal
361 Food Intolerance 13 4.3 4.3 signal
362 Intestinal Resection 19 4.3 4.3 signal
363 Brain Death 11 4.3 4.3 signal
364 Disseminated Intravascular Coagulation 50 4.3 4.3 signal
365 Escherichia Urinary Tract Infection 15 4.3 4.3 signal
366 Cystitis Haemorrhagic 14 4.2 4.2 signal
367 Hyperglycaemia 126 4.2 4.3 signal
368 Mucous Stools 17 4.2 4.2 signal
369 Pyrexia 1,188 4.2 4.4 signal
370 Adrenal Insufficiency 41 4.2 4.2 signal
371 Sinus Tachycardia 48 4.1 4.1 signal
372 Neutropenic Sepsis 24 4.1 4.1 signal
373 Pulse Absent 16 4.1 4.1 signal
374 Mental Status Changes 92 4.0 4.1 signal
375 Candida Infection 55 4.0 4.0 signal
376 Body Temperature Increased 67 4.0 4.0 signal
377 Poor Peripheral Circulation 14 4.0 4.0 signal
378 Oral Disorder 24 4.0 4.0 signal
379 Abscess 52 4.0 4.0 signal
380 Drug-induced Liver Injury 100 4.0 4.0 signal
381 Paronychia 14 3.9 3.9 signal
382 Staphylococcal Infection 107 3.9 4.0 signal
383 Streptococcal Infection 18 3.9 3.9 signal
384 Aspartate Aminotransferase Increased 169 3.9 3.9 signal
385 Drug Delivery System Malfunction 16 3.9 3.9 signal
386 Immunosuppression 27 3.8 3.8 signal
387 Jaundice Cholestatic 11 3.8 3.8 signal
388 Ascites 91 3.8 3.8 signal
389 Eye Movement Disorder 21 3.7 3.7 signal
390 Serum Ferritin Increased 16 3.7 3.7 signal
391 Graft Versus Host Disease 22 3.7 3.7 signal
392 Necrosis 17 3.7 3.7 signal
393 Toxic Encephalopathy 15 3.7 3.7 signal
394 Blood Albumin Decreased 24 3.7 3.7 signal
395 Stomatitis 184 3.7 3.7 signal
396 Cholecystitis 36 3.7 3.7 signal
397 Chronic Myeloid Leukaemia 14 3.7 3.7 signal
398 Acute Hepatic Failure 41 3.7 3.7 signal
399 Cystitis 96 3.7 3.7 signal
400 Abdominal Pain 698 3.7 3.8 signal
401 Aphthous Ulcer 23 3.7 3.7 signal
402 Vitamin B12 Deficiency 12 3.6 3.6 signal
403 Rectal Haemorrhage 128 3.6 3.6 signal
404 Cachexia 15 3.6 3.6 signal
405 Viral Upper Respiratory Tract Infection 14 3.6 3.6 signal
406 Anal Incontinence 26 3.6 3.6 signal
407 Thrombocytopenia 323 3.5 3.6 signal
408 Intestinal Obstruction 108 3.5 3.5 signal
409 Upper Respiratory Tract Infection 133 3.5 3.5 signal
410 Blood Disorder 23 3.5 3.5 signal
411 Blood Pressure Fluctuation 69 3.5 3.5 signal
412 Squamous Cell Carcinoma 27 3.5 3.5 signal
413 Tumour Lysis Syndrome 25 3.5 3.5 signal
414 Hypoxia 100 3.5 3.5 signal
415 Gastrointestinal Motility Disorder 15 3.4 3.4 signal
416 Jaundice 76 3.4 3.4 signal
417 Hepatic Enzyme Abnormal 14 3.4 3.4 signal
418 Dermatitis Acneiform 17 3.4 3.4 signal
419 Lung Neoplasm 12 3.4 3.4 signal
420 Metastasis 20 3.4 3.4 signal
421 Hepatic Lesion 12 3.4 3.4 signal
422 Oral Candidiasis 36 3.4 3.4 signal
423 Metabolic Disorder 16 3.4 3.4 signal
424 Respiratory Failure 201 3.4 3.4 signal
425 Full Blood Count Abnormal 29 3.4 3.4 signal
426 Ammonia Increased 14 3.3 3.3 signal
427 Incorrect Route Of Product Administration 46 3.3 3.3 signal
428 Tuberculosis 35 3.3 3.3 signal
429 Hepatic Cytolysis 33 3.3 3.3 signal
430 Petechiae 28 3.3 3.3 signal
431 Tonsillitis 14 3.3 3.3 signal
432 Platelet Count Decreased 286 3.3 3.3 signal
433 Hyperuricaemia 11 3.3 3.3 signal
434 Cytokine Release Syndrome 51 3.3 3.3 signal
435 Gastroenteritis 39 3.3 3.3 signal
436 Haematochezia 147 3.3 3.3 signal
437 Lymphocyte Count Decreased 47 3.2 3.2 signal
438 Peroneal Nerve Palsy 15 3.2 3.2 signal
439 Acidosis 20 3.2 3.2 signal
440 Hypophosphataemia 19 3.2 3.2 signal
441 Hypoglycaemia 125 3.1 3.2 signal
442 Gamma-glutamyltransferase Increased 57 3.1 3.1 signal
443 Drug Toxicity 35 3.1 3.1 signal
444 Ataxia 30 3.1 3.1 signal
445 Cerebral Ischaemia 13 3.1 3.1 signal
446 Tachycardia 221 3.0 3.1 signal
447 Gastrointestinal Infection 22 3.0 3.0 signal
448 Anaemia 469 3.0 3.0 signal
449 Lymphadenopathy 87 3.0 3.0 signal
450 Shock 56 3.0 3.0 signal
451 Large Intestine Polyp 17 3.0 3.0 signal
452 Gastrointestinal Sounds Abnormal 12 3.0 3.0 signal
453 Hepatic Failure 73 2.9 3.0 signal
454 Cheilitis 13 2.9 2.9 signal
455 Therapy Non-responder 107 2.9 2.9 signal
456 Urosepsis 22 2.9 2.9 signal
457 Blood Pressure Diastolic Increased 11 2.9 2.9 signal
458 Therapeutic Product Effect Decreased 105 2.9 2.9 signal
459 Ileus 29 2.9 2.9 signal
460 Drug Level Increased 39 2.9 2.9 signal
461 Endocarditis 12 2.9 2.9 signal
462 Body Temperature Decreased 23 2.8 2.8 signal
463 Infusion Related Reaction 153 2.8 2.8 signal
464 Dysarthria 87 2.8 2.8 signal
465 Basal Cell Carcinoma 36 2.8 2.8 signal
466 Large Intestine Perforation 16 2.8 2.8 signal
467 Intestinal Haemorrhage 13 2.8 2.8 signal
468 Rhinorrhoea 147 2.8 2.8 signal
469 Pulmonary Toxicity 16 2.8 2.8 signal
470 Blood Count Abnormal 35 2.8 2.8 signal
471 Embolism 19 2.8 2.8 signal
472 Pneumothorax 36 2.8 2.8 signal
473 Granulocytopenia 13 2.8 2.8 signal
474 Electrolyte Imbalance 26 2.8 2.8 signal
475 Faecal Incontinence 11 2.7 2.7 signal
476 Sars-cov-2 Test Positive 30 2.7 2.7 signal
477 Inflammatory Marker Increased 11 2.7 2.7 signal
478 Pallor 61 2.7 2.7 signal
479 Fluid Intake Reduced 11 2.7 2.7 signal
480 Leukaemia 21 2.7 2.7 signal
481 Postoperative Wound Infection 15 2.7 2.7 signal
482 Pleural Effusion 135 2.7 2.7 signal
483 Pericardial Effusion 51 2.7 2.7 signal
484 Liver Function Test Increased 47 2.7 2.7 signal
485 Pathogen Resistance 20 2.7 2.7 signal
486 Myopathy 19 2.7 2.7 signal
487 Injection Site Haematoma 32 2.7 2.7 signal
488 Post Procedural Complication 42 2.7 2.7 signal
489 White Blood Cell Count Decreased 234 2.6 2.6 signal
490 Low Birth Weight Baby 17 2.6 2.6 signal
491 Herpes Zoster 123 2.6 2.6 signal
492 Intestinal Perforation 24 2.6 2.6 signal
493 Therapy Partial Responder 32 2.6 2.6 signal
494 Pharyngitis Streptococcal 23 2.6 2.6 signal
495 Blood Iron Decreased 25 2.6 2.6 signal
496 Disease Recurrence 100 2.6 2.6 signal
497 Hypotonia 21 2.6 2.6 signal
498 Lung Infection 33 2.6 2.6 signal
499 Abnormal Faeces 17 2.5 2.5 signal
500 Inappropriate Antidiuretic Hormone Secretion 21 2.5 2.5 signal
501 Unresponsive To Stimuli 53 2.5 2.5 signal
502 Oral Pain 46 2.5 2.5 signal
503 Hepatic Encephalopathy 19 2.5 2.5 signal
504 Haemoglobin Decreased 208 2.5 2.5 signal
505 Subdural Haematoma 29 2.5 2.5 signal
506 Eosinophilia 35 2.4 2.4 signal
507 Platelet Count Abnormal 12 2.4 2.4 signal
508 Foetal Growth Restriction 12 2.4 2.4 signal
509 Nephropathy Toxic 22 2.4 2.4 signal
510 Obstructive Airways Disorder 22 2.4 2.4 signal
511 Eyelid Ptosis 20 2.4 2.4 signal
512 Bronchiectasis 13 2.4 2.4 signal
513 Pigmentation Disorder 12 2.4 2.4 signal
514 Cholecystitis Acute 11 2.4 2.4 signal
515 Neurological Symptom 11 2.4 2.4 signal
516 Poor Venous Access 20 2.4 2.4 signal
517 Acute Respiratory Failure 37 2.4 2.4 signal
518 Inflammation 99 2.3 2.4 signal
519 Neuropathy Peripheral 182 2.3 2.4 signal
520 Cholelithiasis 63 2.3 2.3 signal
521 Blood Triglycerides Increased 34 2.3 2.3 signal
522 Respiratory Rate Increased 17 2.3 2.3 signal
523 Autoimmune Hepatitis 13 2.3 2.3 signal
524 Impaired Quality Of Life 27 2.3 2.3 signal
525 Decreased Activity 20 2.3 2.3 signal
526 Pneumonia Bacterial 17 2.3 2.3 signal
527 Iron Deficiency Anaemia 17 2.3 2.3 signal
528 Dermatitis Contact 21 2.3 2.3 signal
529 Chills 217 2.3 2.3 signal
530 Injection Site Extravasation 23 2.2 2.2 signal
531 Hyperlipidaemia 22 2.2 2.2 signal
532 Cardiomyopathy 27 2.2 2.2 signal
533 Grand Mal Convulsion 17 2.2 2.2 signal
534 Respiratory Tract Infection 47 2.2 2.2 signal
535 Lymphoma 28 2.2 2.2 signal
536 Infection 260 2.2 2.2 signal
537 Left Ventricular Dysfunction 12 2.2 2.2 signal
538 Hepatitis 46 2.2 2.2 signal
539 Productive Cough 85 2.2 2.2 signal
540 Abdominal Pain Lower 45 2.2 2.2 signal
541 Mouth Haemorrhage 13 2.2 2.2 signal
542 Hypokalaemia 81 2.1 2.2 signal
543 Intentional Product Use Issue 155 2.1 2.2 signal
544 Oropharyngeal Pain 163 2.1 2.2 signal
545 Drug Intolerance 168 2.1 2.1 signal
546 Ejection Fraction Decreased 27 2.1 2.1 signal
547 Treatment Failure 142 2.1 2.1 signal
548 Skin Lesion 47 2.1 2.1 signal
549 Drug Resistance 44 2.1 2.1 signal
550 Mouth Ulceration 36 2.1 2.1 signal
551 Anaphylactic Reaction 94 2.1 2.1 signal
552 Flank Pain 16 2.1 2.1 signal
553 Liver Function Test Abnormal 50 2.1 2.1 signal
554 Hepatocellular Injury 24 2.1 2.1 signal
555 Procedural Complication 13 2.1 2.1 signal
556 Covid-19 Pneumonia 20 2.0 2.0 signal
557 Haemolysis 13 2.0 2.0 signal
558 Hepatic Function Abnormal 62 2.0 2.0 signal
559 Haemolytic Anaemia 15 2.0 2.0 signal
560 Seizure 190 2.0 2.0 signal
561 Neutrophil Count Increased 17 2.0 2.0 signal
562 Haematocrit Decreased 33 2.0 2.0 signal
563 Thrombotic Microangiopathy 16 2.0 2.0 signal
564 Generalised Tonic-clonic Seizure 27 2.0 2.0 signal
565 Haemodialysis 14 2.0 2.0 signal
566 Palmar-plantar Erythrodysaesthesia Syndrome 38 2.0 2.0 no signal
567 Pneumonia 523 2.0 2.0 no signal
568 Blood Pressure Diastolic Decreased 12 2.0 2.0 no signal
569 No Therapeutic Response 20 2.0 2.0 no signal
570 Heart Rate Decreased 57 2.0 2.0 no signal
571 Gastroenteritis Viral 29 1.9 2.0 no signal
572 Vomiting 749 1.9 2.0 no signal
573 C-reactive Protein Increased 58 1.9 1.9 no signal
574 Cerebral Infarction 39 1.9 1.9 no signal
575 Joint Effusion 11 1.9 1.9 no signal
576 Seasonal Allergy 22 1.9 1.9 no signal
577 Glaucoma 30 1.9 1.9 no signal
578 Uveitis 21 1.9 1.9 no signal
579 Gastrointestinal Pain 17 1.9 1.9 no signal
580 Hypocalcaemia 29 1.9 1.9 no signal
581 Liver Injury 37 1.9 1.9 no signal
582 Blood Alkaline Phosphatase Increased 38 1.9 1.9 no signal
583 Injection Site Urticaria 37 1.9 1.9 no signal
584 Skin Infection 17 1.9 1.9 no signal
585 Faeces Soft 11 1.8 1.9 no signal
586 Pneumonitis 41 1.8 1.8 no signal
587 Hypomagnesaemia 21 1.8 1.8 no signal
588 Drug Interaction 239 1.8 1.8 no signal
589 Gastrointestinal Disorder 133 1.8 1.8 no signal
590 Injection Site Irritation 19 1.8 1.8 no signal
591 Condition Aggravated 451 1.8 1.8 no signal
592 Malignant Melanoma 20 1.8 1.8 no signal
593 Metabolic Acidosis 47 1.8 1.8 no signal
594 Urine Output Decreased 13 1.8 1.8 no signal
595 Pulmonary Mass 22 1.8 1.8 no signal
596 Drug Ineffective For Unapproved Indication 82 1.8 1.8 no signal
597 Subarachnoid Haemorrhage 15 1.8 1.8 no signal
598 Oesophagitis 16 1.8 1.8 no signal
599 International Normalised Ratio Increased 42 1.8 1.8 no signal
600 Nasal Congestion 85 1.8 1.8 no signal
601 Therapeutic Product Effect Incomplete 102 1.8 1.8 no signal
602 Osteomyelitis 26 1.7 1.7 no signal
603 Haemorrhoids 28 1.7 1.7 no signal
604 Blood Potassium Decreased 43 1.7 1.7 no signal
605 Musculoskeletal Chest Pain 22 1.7 1.7 no signal
606 Muscular Weakness 161 1.7 1.7 no signal
607 Blood Pressure Abnormal 28 1.7 1.7 no signal
608 Hypotension 282 1.7 1.7 no signal
609 Neuralgia 34 1.7 1.7 no signal
610 Aphasia 42 1.7 1.7 no signal
611 Tooth Infection 18 1.7 1.7 no signal
612 Fluid Overload 20 1.6 1.6 no signal
613 Wheezing 80 1.6 1.6 no signal
614 Dehydration 180 1.6 1.6 no signal
615 Epistaxis 101 1.6 1.6 no signal
616 Brain Oedema 17 1.6 1.6 no signal
617 Ventricular Extrasystoles 14 1.6 1.6 no signal
618 Convulsion 78 1.6 1.6 no signal
619 Epilepsy 41 1.6 1.6 no signal
620 Nervous System Disorder 42 1.6 1.6 no signal
621 Tenderness 14 1.6 1.6 no signal
622 Dialysis 19 1.6 1.6 no signal
623 Haemorrhage Intracranial 20 1.6 1.6 no signal
624 Dyspnoea Exertional 50 1.6 1.6 no signal
625 Transfusion 14 1.6 1.6 no signal
626 Cardio-respiratory Arrest 56 1.6 1.6 no signal
627 Hepatic Enzyme Increased 90 1.6 1.6 no signal
628 Abdominal Distension 137 1.6 1.6 no signal
629 Deep Vein Thrombosis 86 1.6 1.6 no signal
630 Cough 367 1.6 1.6 no signal
631 Acute Kidney Injury 199 1.6 1.6 no signal
632 Off Label Use 1,131 1.6 1.6 no signal
633 Haemoptysis 36 1.6 1.6 no signal
634 Injection Site Nodule 14 1.6 1.6 no signal
635 Muscle Strain 11 1.5 1.5 no signal
636 White Blood Cell Count Increased 49 1.5 1.5 no signal
637 Lethargy 73 1.5 1.5 no signal
638 Folliculitis 13 1.5 1.5 no signal
639 Skin Cancer 27 1.5 1.5 no signal
640 Osteopenia 19 1.5 1.5 no signal
641 Agranulocytosis 23 1.5 1.5 no signal
642 Status Epilepticus 14 1.5 1.5 no signal
643 Photophobia 23 1.5 1.5 no signal
644 Platelet Count Increased 16 1.5 1.5 no signal
645 Interstitial Lung Disease 59 1.5 1.5 no signal
646 Haematemesis 31 1.5 1.5 no signal
647 Sinusitis 125 1.5 1.5 no signal
648 Ligament Sprain 12 1.5 1.5 no signal
649 Night Sweats 39 1.5 1.5 no signal
650 Retinal Detachment 11 1.5 1.5 no signal
651 Ovarian Cyst 12 1.5 1.5 no signal
652 Oxygen Saturation Decreased 66 1.4 1.4 no signal
653 Hepatic Cirrhosis 22 1.4 1.4 no signal
654 Red Blood Cell Sedimentation Rate Increased 13 1.4 1.4 no signal
655 Rib Fracture 24 1.4 1.4 no signal
656 Therapeutic Response Shortened 37 1.4 1.4 no signal
657 Leukocytosis 21 1.4 1.4 no signal
658 Eye Infection 13 1.4 1.4 no signal
659 Nephrolithiasis 53 1.4 1.4 no signal
660 Rash Papular 26 1.4 1.4 no signal
661 Cholecystectomy 13 1.4 1.4 no signal
662 Heart Rate Irregular 26 1.4 1.4 no signal
663 Wrong Technique In Drug Usage Process 42 1.4 1.4 no signal
664 Toxicity To Various Agents 191 1.4 1.4 no signal
665 Bradycardia 60 1.4 1.4 no signal
666 Blood Lactate Dehydrogenase Increased 18 1.4 1.4 no signal
667 Renal Tubular Necrosis 11 1.4 1.4 no signal
668 Red Blood Cell Count Decreased 32 1.4 1.4 no signal
669 Sleep Disorder Due To A General Medical Condition 18 1.4 1.4 no signal
670 Photosensitivity Reaction 18 1.3 1.3 no signal
671 Hernia 21 1.3 1.3 no signal
672 Lactic Acidosis 35 1.3 1.3 no signal
673 Diarrhoea 700 1.3 1.3 no signal
674 Pregnancy 22 1.3 1.3 no signal
675 Urinary Incontinence 32 1.3 1.3 no signal
676 Ear Pain 21 1.3 1.3 no signal
677 Tooth Abscess 11 1.3 1.3 no signal
678 Haemorrhage 112 1.3 1.3 no signal
679 Pulmonary Oedema 48 1.3 1.3 no signal
680 Blood Urea Increased 18 1.3 1.3 no signal
681 Respiratory Tract Congestion 17 1.3 1.3 no signal
682 Cerebral Haemorrhage 38 1.3 1.3 no signal
683 Dermatitis 22 1.3 1.3 no signal
684 Gallbladder Disorder 19 1.3 1.3 no signal
685 Myocarditis 12 1.3 1.3 no signal
686 Injection Site Haemorrhage 84 1.3 1.3 no signal
687 Blood Creatinine Increased 68 1.3 1.3 no signal
688 Gastrointestinal Haemorrhage 86 1.2 1.2 no signal
689 Injection Site Rash 31 1.2 1.2 no signal
690 Back Pain 237 1.2 1.2 no signal
691 Abortion Spontaneous 41 1.2 1.2 no signal
692 Neck Pain 57 1.2 1.2 no signal
693 Injection Site Pain 309 1.2 1.2 no signal
694 Tubulointerstitial Nephritis 19 1.2 1.2 no signal
695 Wound Infection 11 1.2 1.2 no signal
696 Blood Pressure Decreased 67 1.2 1.2 no signal
697 Sinus Disorder 20 1.2 1.2 no signal
698 Nausea 791 1.2 1.2 no signal
699 Covid-19 177 1.2 1.2 no signal
700 Injection Site Pruritus 66 1.2 1.2 no signal
701 Motor Dysfunction 10 1.2 1.2 no signal
702 Hypothermia 10 1.2 1.2 no signal
703 Irritable Bowel Syndrome 21 1.2 1.2 no signal
704 Product Use In Unapproved Indication 240 1.2 1.2 no signal
705 Decreased Appetite 225 1.2 1.2 no signal
706 Liver Disorder 43 1.2 1.2 no signal
707 Bronchitis 72 1.2 1.2 no signal
708 Scratch 10 1.2 1.2 no signal
709 Pharyngitis 12 1.2 1.2 no signal
710 Headache 602 1.2 1.2 no signal
711 Sinus Congestion 13 1.2 1.2 no signal
712 Weight Decreased 267 1.2 1.2 no signal
713 Renal Impairment 80 1.2 1.2 no signal
714 Pain In Jaw 27 1.2 1.2 no signal
715 Heart Rate Increased 94 1.2 1.2 no signal
716 Incontinence 10 1.1 1.1 no signal
717 Circulatory Collapse 16 1.1 1.1 no signal
718 Delirium 32 1.1 1.1 no signal
719 Bone Disorder 17 1.1 1.1 no signal
720 Diplopia 24 1.1 1.1 no signal
721 Vitamin D Deficiency 9 1.1 1.1 no signal
722 Bone Pain 54 1.1 1.1 no signal
723 Orthostatic Hypotension 16 1.1 1.1 no signal
724 Local Swelling 16 1.1 1.1 no signal
725 Increased Appetite 17 1.1 1.1 no signal
726 Ear Infection 24 1.1 1.1 no signal
727 Skin Disorder 30 1.1 1.1 no signal
728 Pulmonary Embolism 86 1.1 1.1 no signal
729 Arthralgia 373 1.1 1.1 no signal
730 Joint Range Of Motion Decreased 12 1.1 1.1 no signal
731 Disease Progression 105 1.1 1.1 no signal
732 Weight Increased 198 1.1 1.1 no signal
733 Cyanosis 14 1.1 1.1 no signal
734 Chromaturia 20 1.1 1.1 no signal
735 Face Oedema 15 1.1 1.1 no signal
736 Immunodeficiency 13 1.1 1.1 no signal
737 Lung Disorder 43 1.1 1.1 no signal
738 Throat Irritation 39 1.1 1.1 no signal
739 Musculoskeletal Discomfort 15 1.1 1.1 no signal
740 Inappropriate Schedule Of Product Administration 154 1.1 1.1 no signal
741 Conjunctivitis 16 1.1 1.1 no signal
742 Drug Exposure During Pregnancy 30 1.1 1.1 no signal
743 Increased Tendency To Bruise 8 1.1 1.1 no signal
744 Influenza 97 1.1 1.1 no signal
745 Kidney Infection 17 1.1 1.1 no signal
746 Abdominal Pain Upper 178 1.1 1.1 no signal
747 Wound 24 1.0 1.0 no signal
748 Dyskinesia 35 1.0 1.0 no signal
749 Swelling Face 56 1.0 1.0 no signal
750 Hypertension 182 1.0 1.0 no signal
751 Neoplasm Progression 30 1.0 1.0 no signal
752 Carpal Tunnel Syndrome 12 1.0 1.0 no signal
753 Rotator Cuff Syndrome 11 1.0 1.0 no signal
754 Caesarean Section 10 1.0 1.0 no signal
755 Incorrect Dose Administered 191 1.0 1.0 no signal
756 Injection Site Induration 11 1.0 1.0 no signal
757 Hypothyroidism 27 1.0 1.0 no signal
758 Haematuria 29 1.0 1.0 no signal
759 Spinal Disorder 8 1.0 1.0 no signal
760 Urinary Retention 28 1.0 1.0 no signal
761 Maternal Exposure During Pregnancy 74 1.0 1.0 no signal
762 Drug Dispensing Error 13 1.0 1.0 no signal
763 Drug Ineffective 1,103 1.0 1.0 no signal
764 Renal Failure Acute 36 1.0 1.0 no signal
765 Depressed Level Of Consciousness 33 1.0 1.0 no signal
766 Altered State Of Consciousness 18 1.0 1.0 no signal
767 Respiratory Disorder 25 1.0 1.0 no signal
768 Dizziness Postural 8 1.0 1.0 no signal
769 Cardiac Arrest 69 1.0 1.0 no signal
770 Synovitis 15 1.0 1.0 no signal
771 Toothache 15 1.0 1.0 no signal
772 Feeling Cold 23 1.0 1.0 no signal
773 Scar 14 1.0 1.0 no signal
774 Rash Erythematous 38 1.0 1.0 no signal
775 Medication Error 45 1.0 1.0 no signal
776 Hypercalcaemia 10 1.0 1.0 no signal
777 Injection Site Erythema 100 1.0 1.0 no signal
778 Constipation 175 1.0 1.0 no signal
779 Renal Failure 108 1.0 1.0 no signal
780 Drug Effect Decreased 44 1.0 1.0 no signal
781 Cyst 10 1.0 1.0 no signal
782 Osteoporosis 33 1.0 1.0 no signal
783 Hyponatraemia 45 1.0 1.0 no signal
784 Loss Of Personal Independence In Daily Activities 38 1.0 1.0 no signal
785 Injection Site Bruising 63 1.0 1.0 no signal
786 Procedural Pain 22 1.0 1.0 no signal
787 Hypersensitivity 147 1.0 1.0 no signal
788 Paraesthesia 125 1.0 1.0 no signal
789 Chest Pain 147 1.0 1.0 no signal
790 Toxic Skin Eruption 8 1.0 1.0 no signal
791 Gastrooesophageal Reflux Disease 63 1.0 1.0 no signal
792 Product Use Issue 146 0.9 0.9 no signal
793 Metastases To Lung 9 0.9 0.9 no signal
794 Inappropriate Schedule Of Drug Administration 56 0.9 0.9 no signal
795 Bronchospasm 11 0.9 0.9 no signal
796 Blood Pressure Increased 117 0.9 0.9 no signal
797 Joint Stiffness 20 0.9 0.9 no signal
798 Gastritis 20 0.9 0.9 no signal
799 Immune System Disorder 10 0.9 0.9 no signal
800 General Physical Health Deterioration 87 0.9 0.9 no signal
801 Pain In Extremity 223 0.9 0.9 no signal
802 Pulmonary Congestion 10 0.9 0.9 no signal
803 Hypoaesthesia 113 0.9 0.9 no signal
804 Ulcer 12 0.9 0.9 no signal
805 Intervertebral Disc Degeneration 7 0.9 0.9 no signal
806 Syncope 75 0.9 0.9 no signal
807 Asthenia 281 0.9 0.9 no signal
808 Therapeutic Response Decreased 45 0.9 0.9 no signal
809 Blood Sodium Decreased 14 0.9 0.9 no signal
810 Sensory Disturbance 12 0.9 0.9 no signal
811 Oedema Peripheral 91 0.9 0.9 no signal
812 Thyroid Cancer 9 0.9 0.9 no signal
813 Throat Tightness 20 0.9 0.9 no signal
814 Exposure During Pregnancy 46 0.9 0.9 no signal
815 Injection Site Swelling 56 0.9 0.9 no signal
816 Faeces Discoloured 16 0.9 0.9 no signal
817 Therapeutic Response Unexpected 33 0.9 0.9 no signal
818 Dysuria 27 0.9 0.9 no signal
819 Autoimmune Disorder 7 0.9 0.9 no signal
820 Contusion 70 0.9 0.9 no signal
821 Peritonitis 15 0.9 0.9 no signal
822 Ventricular Tachycardia 12 0.9 0.9 no signal
823 Ventricular Fibrillation 8 0.9 0.9 no signal
824 Feeling Hot 44 0.9 0.9 no signal
825 Dysstasia 21 0.9 0.9 no signal
826 Hypertensive Crisis 8 0.9 0.9 no signal
827 Nasopharyngitis 132 0.9 0.9 no signal
828 Fatigue 554 0.9 0.9 no signal
829 Coordination Abnormal 10 0.9 0.9 no signal
830 Arthritis 56 0.9 0.9 no signal
831 Skin Reaction 10 0.9 0.9 no signal
832 Tendonitis 11 0.9 0.9 no signal
833 Rebound Effect 8 0.9 0.9 no signal
834 Bladder Disorder 7 0.9 0.9 no signal
835 Rash 305 0.9 0.9 no signal
836 Oedema 38 0.9 0.9 no signal
837 Brain Injury 7 0.8 0.8 no signal
838 Dysphagia 66 0.8 0.8 no signal
839 Psoriasis 91 0.8 0.8 no signal
840 Thrombosis 56 0.8 0.8 no signal
841 Hiatus Hernia 9 0.8 0.8 no signal
842 Cataract 41 0.8 0.8 no signal
843 Sluggishness 7 0.8 0.8 no signal
844 Vasculitis 8 0.8 0.8 no signal
845 Eye Discharge 7 0.8 0.8 no signal
846 Urinary Tract Infection 116 0.8 0.8 no signal
847 Pulmonary Fibrosis 13 0.8 0.8 no signal
848 Drug Effect Incomplete 25 0.8 0.8 no signal
849 Malaise 298 0.8 0.8 no signal
850 Weight Fluctuation 7 0.8 0.8 no signal
851 Sleep Disorder 47 0.8 0.8 no signal
852 Adverse Drug Reaction 60 0.8 0.8 no signal
853 Gout 12 0.8 0.8 no signal
854 Blood Pressure Systolic Increased 13 0.8 0.8 no signal
855 Musculoskeletal Pain 35 0.8 0.8 no signal
856 Localised Infection 16 0.8 0.8 no signal
857 Amenorrhoea 11 0.8 0.8 no signal
858 Gingival Bleeding 9 0.8 0.8 no signal
859 Peripheral Coldness 9 0.8 0.8 no signal
860 Type 2 Diabetes Mellitus 22 0.8 0.8 no signal
861 Diverticulitis 18 0.8 0.8 no signal
862 Generalised Oedema 8 0.8 0.8 no signal
863 Rash Pruritic 35 0.8 0.8 no signal
864 Body Height Decreased 7 0.8 0.8 no signal
865 Laryngitis 7 0.8 0.8 no signal
866 Mass 9 0.8 0.8 no signal
867 Device Issue 56 0.8 0.8 no signal
868 Myalgia 109 0.8 0.8 no signal
869 Gait Disturbance 123 0.8 0.8 no signal
870 Impaired Healing 21 0.8 0.8 no signal
871 Electrocardiogram Qt Prolonged 23 0.8 0.8 no signal
872 Melaena 14 0.8 0.8 no signal
873 Loss Of Consciousness 81 0.8 0.8 no signal
874 Injection Site Warmth 13 0.8 0.8 no signal
875 Premature Baby 19 0.8 0.8 no signal
876 Laceration 6 0.8 0.8 no signal
877 Chest Discomfort 64 0.8 0.8 no signal
878 Infusion Site Pain 8 0.8 0.8 no signal
879 Paralysis 9 0.8 0.8 no signal
880 Diabetic Ketoacidosis 15 0.8 0.8 no signal
881 Eye Swelling 23 0.8 0.8 no signal
882 Hyperhidrosis 80 0.8 0.8 no signal
883 Nodule 8 0.7 0.7 no signal
884 Laboratory Test Abnormal 18 0.7 0.7 no signal
885 Poor Quality Sleep 13 0.7 0.7 no signal
886 Muscle Twitching 14 0.7 0.7 no signal
887 Influenza Like Illness 50 0.7 0.7 no signal
888 Colon Cancer 9 0.7 0.7 no signal
889 Stress 43 0.7 0.7 no signal
890 Lower Respiratory Tract Infection 27 0.7 0.7 no signal
891 Full Blood Count Decreased 12 0.7 0.7 no signal
892 Middle Insomnia 11 0.7 0.7 no signal
893 Ear Discomfort 6 0.7 0.7 no signal
894 Dyspnoea 331 0.7 0.7 no signal
895 Flatulence 33 0.7 0.7 no signal
896 Injection Site Reaction 40 0.7 0.7 no signal
897 Unevaluable Event 44 0.7 0.7 no signal
898 Device Malfunction 39 0.7 0.7 no signal
899 Blood Cholesterol Increased 27 0.7 0.7 no signal
900 Flushing 59 0.7 0.7 no signal
901 Oral Discomfort 8 0.7 0.7 no signal
902 Rash Macular 20 0.7 0.7 no signal
903 Dystonia 11 0.7 0.7 no signal
904 Eating Disorder 12 0.7 0.7 no signal
905 Impaired Work Ability 12 0.7 0.7 no signal
906 Agitation 41 0.7 0.7 no signal
907 Speech Disorder 29 0.7 0.7 no signal
908 Abnormal Behaviour 22 0.7 0.7 no signal
909 Acne 42 0.7 0.7 no signal
910 Drug Hypersensitivity 107 0.7 0.7 no signal
911 Pelvic Pain 10 0.7 0.7 no signal
912 Alopecia 108 0.7 0.7 no signal
913 Irritability 33 0.7 0.7 no signal
914 Cardiac Failure 44 0.7 0.7 no signal
915 Dental Caries 6 0.7 0.7 no signal
916 Osteoarthritis 23 0.7 0.7 no signal
917 Foot Deformity 6 0.7 0.7 no signal
918 Visual Acuity Reduced 18 0.7 0.7 no signal
919 Sneezing 12 0.7 0.7 no signal
920 Ocular Hyperaemia 25 0.7 0.7 no signal
921 Treatment Noncompliance 29 0.6 0.6 no signal
922 Eye Inflammation 5 0.6 0.6 no signal
923 Scab 6 0.6 0.6 no signal
924 Pulmonary Hypertension 11 0.6 0.6 no signal
925 Gastric Ulcer 10 0.6 0.6 no signal
926 Hypersomnia 15 0.6 0.6 no signal
927 Neoplasm 6 0.6 0.6 no signal
928 Abasia 13 0.6 0.6 no signal
929 Therapy Change 5 0.6 0.6 no signal
930 Surgery 30 0.6 0.6 no signal
931 Tremor 86 0.6 0.6 no signal
932 Foetal Exposure During Pregnancy 42 0.6 0.6 no signal
933 Musculoskeletal Stiffness 45 0.6 0.6 no signal
934 Pharyngeal Oedema 8 0.6 0.6 no signal
935 Spinal Pain 6 0.6 0.6 no signal
936 Urticaria 85 0.6 0.6 no signal
937 Cold Sweat 9 0.6 0.6 no signal
938 Psychotic Disorder 15 0.6 0.6 no signal
939 Macular Degeneration 6 0.6 0.6 no signal
940 Mobility Decreased 36 0.6 0.6 no signal
941 Vaginal Discharge 5 0.6 0.6 no signal
942 Blindness Unilateral 7 0.6 0.6 no signal
943 Rash Maculo-papular 11 0.6 0.6 no signal
944 Movement Disorder 16 0.6 0.6 no signal
945 Presyncope 12 0.6 0.6 no signal
946 Muscle Tightness 8 0.6 0.6 no signal
947 Mental Impairment 12 0.6 0.6 no signal
948 Fluid Retention 25 0.6 0.6 no signal
949 Product Prescribing Issue 10 0.6 0.6 no signal
950 Temperature Intolerance 5 0.6 0.6 no signal
951 Confusional State 79 0.6 0.6 no signal
952 Erythema 100 0.6 0.6 no signal
953 Hyperkalaemia 17 0.6 0.6 no signal
954 Paraesthesia Oral 7 0.6 0.6 no signal
955 Injection Site Discolouration 6 0.6 0.6 no signal
956 Blister 27 0.6 0.6 no signal
957 Skin Discolouration 22 0.6 0.6 no signal
958 Pain 293 0.6 0.6 no signal
959 Meningioma 7 0.6 0.6 no signal
960 Renal Pain 5 0.6 0.6 no signal
961 Retching 10 0.6 0.6 no signal
962 Vision Blurred 64 0.6 0.6 no signal
963 Mydriasis 6 0.6 0.6 no signal
964 Dizziness 233 0.6 0.6 no signal
965 Drug Dose Omission 78 0.6 0.6 no signal
966 Joint Swelling 56 0.6 0.6 no signal
967 Back Injury 5 0.6 0.6 no signal
968 Vertigo 28 0.6 0.6 no signal
969 Anorexia 6 0.6 0.6 no signal
970 Pulmonary Thrombosis 5 0.6 0.6 no signal
971 Complication Associated With Device 6 0.6 0.6 no signal
972 Tooth Fracture 5 0.6 0.6 no signal
973 Migraine 43 0.6 0.5 no signal
974 Gait Inability 15 0.6 0.6 no signal
975 Adverse Reaction 6 0.5 0.5 no signal
976 Pneumonia Aspiration 11 0.5 0.5 no signal
977 Premature Delivery 7 0.5 0.5 no signal
978 Eczema 22 0.5 0.5 no signal
979 Abdominal Discomfort 73 0.5 0.5 no signal
980 Blood Glucose Decreased 21 0.5 0.5 no signal
981 Coronary Artery Occlusion 6 0.5 0.5 no signal
982 Ovarian Cancer 4 0.5 0.5 no signal
983 Gastric Haemorrhage 5 0.5 0.5 no signal
984 Diabetes Mellitus 33 0.5 0.5 no signal
985 Muscle Spasms 79 0.5 0.5 no signal
986 Cognitive Disorder 20 0.5 0.5 no signal
987 Anaphylactic Shock 11 0.5 0.5 no signal
988 Renal Disorder 20 0.5 0.5 no signal
989 Post Procedural Haemorrhage 5 0.5 0.5 no signal
990 Disorientation 17 0.5 0.5 no signal
991 Thinking Abnormal 8 0.5 0.5 no signal
992 Abortion Induced 4 0.5 0.5 no signal
993 Skin Fissures 8 0.5 0.5 no signal
994 Lip Swelling 14 0.5 0.5 no signal
995 Therapy Interrupted 29 0.5 0.5 no signal
996 Pericarditis 7 0.5 0.5 no signal
997 Upper Gastrointestinal Haemorrhage 7 0.5 0.5 no signal
998 Affect Lability 4 0.5 0.5 no signal
999 Apathy 6 0.5 0.5 no signal
1000 Drug Prescribing Error 8 0.5 0.5 no signal
1001 Asthma 46 0.5 0.5 no signal
1002 Blood Creatine Phosphokinase Increased 12 0.5 0.5 no signal
1003 Coeliac Disease 4 0.5 0.5 no signal
1004 Balance Disorder 35 0.5 0.5 no signal
1005 Stevens-johnson Syndrome 9 0.5 0.5 no signal
1006 Palpitations 47 0.5 0.5 no signal
1007 Lacrimation Increased 12 0.5 0.5 no signal
1008 Tooth Extraction 5 0.5 0.5 no signal
1009 Syringe Issue 7 0.5 0.5 no signal
1010 Amnesia 26 0.5 0.5 no signal
1011 Injury Associated With Device 8 0.5 0.5 no signal
1012 Dyspepsia 39 0.5 0.5 no signal
1013 Systemic Lupus Erythematosus 14 0.5 0.5 no signal
1014 Respiratory Arrest 11 0.5 0.5 no signal
1015 Hip Arthroplasty 6 0.5 0.5 no signal
1016 Helicobacter Infection 4 0.5 0.5 no signal
1017 Intraocular Pressure Increased 5 0.5 0.5 no signal
1018 Somnolence 78 0.5 0.5 no signal
1019 Limb Discomfort 12 0.5 0.5 no signal
1020 Transient Ischaemic Attack 13 0.5 0.5 no signal
1021 Deafness 10 0.5 0.5 no signal
1022 Head Injury 12 0.5 0.5 no signal
1023 Anxiety 108 0.5 0.5 no signal
1024 Pruritus 143 0.5 0.5 no signal
1025 Hallucination, Auditory 6 0.5 0.5 no signal
1026 Drug Effective For Unapproved Indication 11 0.5 0.5 no signal
1027 Breast Pain 4 0.5 0.5 no signal
1028 Drug Administered At Inappropriate Site 4 0.5 0.5 no signal
1029 Eye Haemorrhage 5 0.5 0.5 no signal
1030 Hip Fracture 12 0.5 0.5 no signal
1031 Depression 85 0.5 0.4 no signal
1032 Therapy Cessation 19 0.5 0.5 no signal
1033 Suicidal Ideation 34 0.5 0.4 no signal
1034 Burning Sensation 26 0.5 0.4 no signal
1035 Underdose 27 0.4 0.4 no signal
1036 Oesophageal Carcinoma 11 0.4 0.4 no signal
1037 Pruritus Generalised 8 0.4 0.4 no signal
1038 Eye Pruritus 12 0.4 0.4 no signal
1039 Fall 121 0.4 0.4 no signal
1040 Malignant Neoplasm Progression 37 0.4 0.4 no signal
1041 Eye Pain 20 0.4 0.4 no signal
1042 Central Nervous System Lesion 5 0.4 0.4 no signal
1043 Osteonecrosis Of Jaw 9 0.4 0.4 no signal
1044 Pollakiuria 15 0.4 0.4 no signal
1045 Arthropathy 20 0.4 0.4 no signal
1046 Adverse Event 33 0.4 0.4 no signal
1047 Tooth Disorder 8 0.4 0.4 no signal
1048 Glossodynia 8 0.4 0.4 no signal
1049 Product Availability Issue 8 0.4 0.4 no signal
1050 Drug Effect Less Than Expected 5 0.4 0.4 no signal
1051 Menorrhagia 7 0.4 0.4 no signal
1052 Death 300 0.4 0.4 no signal
1053 Blindness 14 0.4 0.4 no signal
1054 Angioedema 15 0.4 0.4 no signal
1055 Aggression 17 0.4 0.4 no signal
1056 Rhabdomyolysis 14 0.4 0.4 no signal
1057 Cerebrovascular Accident 57 0.4 0.4 no signal
1058 Bone Loss 5 0.4 0.4 no signal
1059 Illness 33 0.4 0.4 no signal
1060 Hepatitis C 4 0.4 0.4 no signal
1061 Blood Thyroid Stimulating Hormone Increased 3 0.4 0.4 no signal
1062 Poisoning Deliberate 3 0.4 0.4 no signal
1063 Drug Administration Error 10 0.4 0.4 no signal
1064 Personality Change 3 0.4 0.4 no signal
1065 Feeling Abnormal 77 0.4 0.4 no signal
1066 Hot Flush 24 0.4 0.4 no signal
1067 Insomnia 84 0.4 0.4 no signal
1068 Injury 22 0.4 0.4 no signal
1069 Intentional Product Misuse 27 0.4 0.4 no signal
1070 Hospitalisation 47 0.4 0.4 no signal
1071 Decreased Immune Responsiveness 3 0.4 0.4 no signal
1072 Tinnitus 14 0.4 0.4 no signal
1073 Crying 11 0.4 0.4 no signal
1074 Panic Attack 11 0.4 0.4 no signal
1075 Accidental Overdose 11 0.4 0.4 no signal
1076 Chronic Kidney Disease 23 0.4 0.4 no signal
1077 Neoplasm Malignant 20 0.4 0.4 no signal
1078 Peritonitis Bacterial 3 0.4 0.4 no signal
1079 Ill-defined Disorder 18 0.4 0.4 no signal
1080 Anger 10 0.4 0.4 no signal
1081 Euphoric Mood 3 0.4 0.4 no signal
1082 Depressed Mood 15 0.3 0.3 no signal
1083 Diabetes Mellitus Inadequate Control 5 0.3 0.3 no signal
1084 Discomfort 17 0.3 0.3 no signal
1085 Incorrect Drug Administration Duration 8 0.3 0.3 no signal
1086 Hallucination 21 0.3 0.3 no signal
1087 Breast Cancer Metastatic 3 0.3 0.3 no signal
1088 Swelling 26 0.3 0.3 no signal
1089 Atrial Fibrillation 27 0.3 0.3 no signal
1090 Dysgeusia 20 0.3 0.3 no signal
1091 Vaginal Haemorrhage 11 0.3 0.3 no signal
1092 Dysphonia 15 0.3 0.3 no signal
1093 Mental Disorder 11 0.3 0.3 no signal
1094 Myocardial Infarction 44 0.3 0.3 no signal
1095 Device Deployment Issue 3 0.3 0.3 no signal
1096 Schizophrenia 3 0.3 0.3 no signal
1097 Respiratory Depression 3 0.3 0.3 no signal
1098 Injection Site Mass 9 0.3 0.3 no signal
1099 Peripheral Swelling 37 0.3 0.3 no signal
1100 Tooth Loss 5 0.3 0.3 no signal
1101 Product Dose Omission Issue 68 0.3 0.3 no signal
1102 Poisoning 3 0.3 0.3 no signal
1103 Cardiac Failure Congestive 19 0.3 0.3 no signal
1104 Metrorrhagia 4 0.3 0.3 no signal
1105 Dysmenorrhoea 3 0.3 0.3 no signal
1106 Pharmaceutical Product Complaint 6 0.3 0.3 no signal
1107 Colorectal Cancer 11 0.3 0.3 no signal
1108 Dry Eye 11 0.3 0.3 no signal
1109 Incorrect Product Storage 3 0.3 0.3 no signal
1110 Breast Cancer Female 6 0.3 0.3 no signal
1111 Dry Mouth 18 0.3 0.3 no signal
1112 Overdose 48 0.3 0.3 no signal
1113 Bone Density Decreased 7 0.3 0.3 no signal
1114 Incorrect Route Of Drug Administration 8 0.3 0.3 no signal
1115 Dermatitis Atopic 11 0.3 0.3 no signal
1116 Akathisia 3 0.3 0.3 no signal
1117 Application Site Rash 3 0.3 0.3 no signal
1118 Skin Exfoliation 18 0.3 0.3 no signal
1119 Prostatic Specific Antigen Increased 3 0.3 0.3 no signal
1120 Chronic Obstructive Pulmonary Disease 11 0.3 0.3 no signal
1121 Needle Issue 6 0.3 0.3 no signal
1122 Memory Impairment 28 0.2 0.2 no signal
1123 Disturbance In Attention 11 0.2 0.2 no signal
1124 Blood Glucose Increased 38 0.2 0.2 no signal
1125 Extrapyramidal Disorder 5 0.2 0.2 no signal
1126 Device Failure 3 0.2 0.2 no signal
1127 Product Dose Omission 13 0.2 0.2 no signal
1128 Completed Suicide 16 0.2 0.2 no signal
1129 Product Storage Error 16 0.2 0.2 no signal
1130 Prostate Cancer 15 0.2 0.2 no signal
1131 Breast Cancer 17 0.2 0.2 no signal
1132 Visual Impairment 22 0.2 0.2 no signal
1133 Intentional Overdose 11 0.2 0.2 no signal
1134 Dry Skin 20 0.2 0.2 no signal
1135 Application Site Erythema 4 0.2 0.2 no signal
1136 Menstruation Irregular 4 0.2 0.2 no signal
1137 Cardiac Disorder 13 0.2 0.2 no signal
1138 Pancreatic Carcinoma 4 0.2 0.2 no signal
1139 Product Quality Issue 18 0.2 0.2 no signal
1140 No Adverse Event 23 0.2 0.2 no signal
1141 Wrong Technique In Product Usage Process 24 0.1 0.1 no signal
1142 Bladder Cancer 7 0.1 0.1 no signal
1143 Accidental Exposure To Product 11 0.1 0.1 no signal
1144 Emotional Distress 13 0.1 0.1 no signal
1145 Rheumatoid Arthritis 12 0.1 0.1 no signal
1146 Renal Cancer 5 0.1 0.1 no signal
1147 Drug Dependence 12 0.1 0.1 no signal