Drug

Nicotine Polacrilex Mini

1,133 flagged reaction(s) · 62,960 total co-reports · max PRR 1,962.7

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Vaginal Flatulence	177	1,962.7	1,986.3	signal
2	Rhesus Incompatibility	68	1,778.4	1,786.5	signal
3	Plethysmography	14	1,617.1	1,618.6	signal
4	Truncus Arteriosus Persistent	74	820.6	824.7	signal
5	Tobacco Poisoning	30	533.1	534.2	signal
6	Myocardial Stunning	24	305.2	305.7	signal
7	Tobacco Interaction	16	233.4	233.7	signal
8	Lung Diffusion Disorder	18	180.8	181.0	signal
9	Female Genital Tract Fistula	181	165.3	167.3	signal
10	Tobacco Abuse	50	143.2	143.7	signal
11	Nicotine Dependence	715	140.6	147.6	signal
12	Cardiac Septal Defect	54	113.2	113.6	signal
13	Tremor Neonatal	32	107.7	107.9	signal
14	Diarrhoea Neonatal	9	105.7	105.8	signal
15	Multiple Drug Overdose Accidental	32	104.1	104.3	signal
16	Radiculopathy	180	103.0	104.2	signal
17	Congenital Cardiovascular Anomaly	57	101.0	101.4	signal
18	Weight Decrease Neonatal	13	100.1	100.2	signal
19	Neutropenia Neonatal	15	100.0	100.1	signal
20	Proctitis	183	98.1	99.3	signal
21	Poor Feeding Infant	69	97.0	97.4	signal
22	Chronic Sinusitis	239	95.8	97.3	signal
23	Idiopathic Interstitial Pneumonia	18	77.5	77.6	signal
24	Congenital Tricuspid Valve Incompetence	10	77.0	77.1	signal
25	Jaundice Neonatal	96	74.9	75.4	signal
26	Mediastinal Mass	18	70.3	70.4	signal
27	Macular Degeneration	563	69.7	72.4	signal
28	Adenoidectomy	18	68.9	69.0	signal
29	Congenital Pulmonary Hypertension	9	67.8	67.8	signal
30	Necrosis Ischaemic	20	63.4	63.5	signal
31	Pulmonary Eosinophilia	19	60.3	60.3	signal
32	Neonatal Aspiration	13	57.2	57.3	signal
33	Breech Presentation	49	56.9	57.1	signal
34	Postmortem Blood Drug Level Increased	14	56.4	56.5	signal
35	Respiratory Gas Exchange Disorder	14	55.1	55.2	signal
36	Substance Dependence	25	54.5	54.6	signal
37	Sputum Purulent	24	52.8	52.9	signal
38	Tooth Erosion	40	51.1	51.2	signal
39	Exposure During Breast Feeding	114	49.3	49.7	signal
40	Loss Of Proprioception	11	49.2	49.2	signal
41	Exposure Via Breast Milk	126	46.7	47.1	signal
42	Foetal Disorder	27	46.4	46.5	signal
43	Bronchial Wall Thickening	19	37.8	37.8	signal
44	Hyperbilirubinaemia Neonatal	15	37.2	37.2	signal
45	Foetal Distress Syndrome	54	36.7	36.8	signal
46	Drug Withdrawal Syndrome Neonatal	375	36.1	37.0	signal
47	Gastroschisis	12	35.9	36.0	signal
48	Diaphragmatic Disorder	19	35.5	35.5	signal
49	Low Birth Weight Baby	175	31.6	32.0	signal
50	Agitation Neonatal	20	30.1	30.1	signal
51	Product Adhesion Issue	727	29.4	30.9	signal
52	Secondary Immunodeficiency	24	28.8	28.8	signal
53	Pneumonia Streptococcal	22	28.7	28.8	signal
54	Tobacco User	30	28.7	28.8	signal
55	Substance Abuse	157	27.6	27.9	signal
56	Drug Detoxification	17	27.3	27.3	signal
57	Alcohol Abuse	51	27.1	27.2	signal
58	Pulmonary Granuloma	21	26.1	26.1	signal
59	Vaginal Discharge	182	25.9	26.2	signal
60	Cleft Lip	15	24.2	24.3	signal
61	Umbilical Cord Around Neck	10	24.0	24.0	signal
62	Beta Haemolytic Streptococcal Infection	21	23.9	23.9	signal
63	Alcohol Withdrawal Syndrome	14	22.8	22.8	signal
64	Multiple Drug Overdose	80	22.7	22.8	signal
65	Paraesthesia Oral	228	22.6	23.0	signal
66	Premature Delivery	251	22.4	22.8	signal
67	Infective Exacerbation Of Chronic Obstructive Airways Disease	10	22.2	22.2	signal
68	Borderline Personality Disorder	11	22.1	22.1	signal
69	Ventricular Septal Defect	89	22.0	22.2	signal
70	Pressure Of Speech	10	21.9	21.9	signal
71	Placenta Praevia	12	21.6	21.6	signal
72	Heart Disease Congenital	54	21.6	21.6	signal
73	Bronchial Secretion Retention	19	21.4	21.5	signal
74	Neonatal Respiratory Distress	13	21.4	21.4	signal
75	Oral Candidiasis	192	21.0	21.3	signal
76	Microcephaly	18	20.2	20.2	signal
77	Feeding Disorder Neonatal	15	20.1	20.2	signal
78	Accidental Death	26	20.0	20.0	signal
79	Ophthalmoplegia	22	19.9	20.0	signal
80	Axonal Neuropathy	12	19.8	19.9	signal
81	Cardiac Death	17	19.8	19.8	signal
82	Application Site Scar	17	19.3	19.3	signal
83	Counterfeit Product Administered	17	19.0	19.0	signal
84	Reversible Cerebral Vasoconstriction Syndrome	26	18.9	18.9	signal
85	Cytokine Storm	9	18.8	18.8	signal
86	Antisocial Behaviour	13	18.3	18.4	signal
87	Alcohol Interaction	25	18.2	18.3	signal
88	Treatment Noncompliance	664	17.4	18.1	signal
89	Myocardial Fibrosis	10	16.9	16.9	signal
90	Bronchial Hyperreactivity	14	16.5	16.5	signal
91	Jaw Fracture	25	16.4	16.4	signal
92	Tonsillectomy	19	16.1	16.2	signal
93	Neonatal Disorder	18	16.0	16.1	signal
94	Mycobacterial Infection	19	15.7	15.7	signal
95	Neuropsychiatric Symptoms	10	15.5	15.5	signal
96	Premature Baby	323	15.2	15.5	signal
97	Respiratory Disorder Neonatal	17	15.2	15.2	signal
98	Application Site Dermatitis	10	15.1	15.1	signal
99	Nasal Oedema	19	15.0	15.1	signal
100	Non-alcoholic Steatohepatitis	11	14.9	14.9	signal
101	Premature Separation Of Placenta	16	14.6	14.7	signal
102	Rhonchi	14	14.3	14.3	signal
103	Prinzmetal Angina	10	14.3	14.3	signal
104	Schizoaffective Disorder	18	14.2	14.3	signal
105	Disinhibition	16	14.1	14.1	signal
106	Cleft Palate	19	13.9	13.9	signal
107	Cleft Lip And Palate	11	13.8	13.8	signal
108	Methaemoglobinaemia	22	13.6	13.6	signal
109	Oligohydramnios	32	13.5	13.6	signal
110	Bone Demineralisation	10	13.4	13.4	signal
111	Chronic Kidney Disease-mineral And Bone Disorder	10	13.2	13.2	signal
112	Antipsychotic Drug Level Increased	26	13.1	13.1	signal
113	Foetal Exposure During Pregnancy	744	13.0	13.6	signal
114	Gastric Dilatation	15	12.8	12.8	signal
115	Intentional Drug Misuse	190	12.7	12.8	signal
116	Application Site Urticaria	20	12.5	12.5	signal
117	Body Temperature Abnormal	16	12.3	12.3	signal
118	Gestational Hypertension	11	12.2	12.2	signal
119	Application Site Warmth	11	12.2	12.2	signal
120	Application Site Pruritus	193	12.0	12.2	signal
121	Gambling Disorder	23	12.0	12.0	signal
122	Exposure Via Father	11	11.8	11.8	signal
123	Claustrophobia	9	11.7	11.7	signal
124	Clostridium Test Positive	18	11.7	11.7	signal
125	Compulsive Shopping	17	11.6	11.6	signal
126	Application Site Erythema	216	11.6	11.8	signal
127	Nephrogenic Anaemia	38	11.5	11.5	signal
128	Application Site Rash	111	11.4	11.5	signal
129	Blood Immunoglobulin E Increased	19	11.0	11.1	signal
130	Drug Effect Increased	25	11.0	11.0	signal
131	Substance Use	12	11.0	11.0	signal
132	Mean Cell Volume Decreased	12	11.0	11.0	signal
133	Incorrect Drug Administration Duration	221	11.0	11.1	signal
134	Application Site Vesicles	50	10.9	10.9	signal
135	Product Monitoring Error	11	10.9	10.9	signal
136	Gun Shot Wound	14	10.4	10.4	signal
137	Procedural Pain	203	10.4	10.5	signal
138	Drug Screen Positive	57	10.2	10.3	signal
139	Frequent Bowel Movements	194	10.2	10.3	signal
140	Abnormal Dreams	200	10.2	10.3	signal
141	Alcohol Poisoning	19	10.1	10.1	signal
142	Mean Cell Haemoglobin Decreased	13	10.0	10.0	signal
143	Regurgitation	24	9.9	9.9	signal
144	Emphysema	71	9.9	10.0	signal
145	Abortion Induced	65	9.8	9.8	signal
146	Rebound Acid Hypersecretion	21	9.7	9.7	signal
147	Left Ventricular Hypertrophy	29	9.6	9.6	signal
148	Application Site Burn	33	9.4	9.4	signal
149	Caesarean Section	78	9.4	9.4	signal
150	Mean Cell Haemoglobin Concentration Decreased	11	9.3	9.4	signal
151	Dental Caries	73	9.3	9.4	signal
152	Lobar Pneumonia	12	9.0	9.0	signal
153	Drug Toxicity	88	9.0	9.1	signal
154	Hyperparathyroidism Secondary	16	8.9	8.9	signal
155	Vitamin B12 Deficiency	25	8.8	8.8	signal
156	Bronchiolitis	22	8.8	8.8	signal
157	Premature Labour	35	8.7	8.7	signal
158	Maternal Drugs Affecting Foetus	47	8.6	8.6	signal
159	Oedema Mouth	20	8.6	8.6	signal
160	Application Site Swelling	30	8.5	8.5	signal
161	Drug Abuser	37	8.4	8.4	signal
162	Drug Use Disorder	49	8.4	8.4	signal
163	Retroperitoneal Haematoma	13	8.4	8.4	signal
164	Pre-eclampsia	28	8.3	8.4	signal
165	Hypertensive Heart Disease	11	8.3	8.3	signal
166	Obstructive Airways Disorder	64	8.1	8.1	signal
167	Bronchitis Chronic	14	8.0	8.1	signal
168	Colitis	214	8.0	8.1	signal
169	Patent Ductus Arteriosus	22	7.8	7.8	signal
170	Euphoric Mood	56	7.7	7.7	signal
171	Aortic Arteriosclerosis	14	7.7	7.7	signal
172	Small For Dates Baby	27	7.6	7.7	signal
173	Homicidal Ideation	22	7.6	7.6	signal
174	Stenosis	10	7.6	7.6	signal
175	Atelectasis	52	7.6	7.6	signal
176	Neonatal Respiratory Distress Syndrome	19	7.6	7.6	signal
177	Rectal Haemorrhage	228	7.5	7.6	signal
178	Application Site Irritation	65	7.4	7.4	signal
179	Bile Duct Obstruction	10	7.3	7.3	signal
180	Priapism	18	7.3	7.3	signal
181	Arteriosclerosis Coronary Artery	34	7.3	7.3	signal
182	Maternal Exposure During Pregnancy	447	7.2	7.3	signal
183	Electrocardiogram St Segment Depression	11	7.0	7.0	signal
184	Intentional Underdose	36	7.0	7.0	signal
185	Application Site Reaction	35	7.0	7.0	signal
186	Full Blood Count Abnormal	52	7.0	7.0	signal
187	Functional Gastrointestinal Disorder	17	6.9	6.9	signal
188	Maternal Exposure During Breast Feeding	19	6.8	6.8	signal
189	Umbilical Hernia	22	6.6	6.6	signal
190	Economic Problem	72	6.6	6.6	signal
191	Application Site Discolouration	19	6.6	6.6	signal
192	Transfusion	49	6.6	6.6	signal
193	Foetal Growth Restriction	28	6.5	6.6	signal
194	Colitis Ulcerative	204	6.5	6.5	signal
195	Drug Abuse	381	6.4	6.6	signal
196	Product Complaint	112	6.3	6.4	signal
197	Vasodilatation	11	6.2	6.2	signal
198	Red Cell Distribution Width Increased	18	6.1	6.1	signal
199	Alcohol Use	16	6.1	6.1	signal
200	Potentiating Drug Interaction	14	6.0	6.0	signal
201	Snoring	16	6.0	6.0	signal
202	Substance Use Disorder	13	6.0	6.0	signal
203	Bipolar Disorder	46	5.9	5.9	signal
204	Sinus Tachycardia	59	5.9	5.9	signal
205	Nasal Polyps	20	5.8	5.9	signal
206	Therapeutic Product Effect Incomplete	293	5.8	5.9	signal
207	Drug Tolerance	21	5.8	5.8	signal
208	Application Site Pain	91	5.8	5.9	signal
209	Nightmare	143	5.8	5.8	signal
210	Self-injurious Ideation	17	5.7	5.7	signal
211	Ventricular Hypokinesia	13	5.7	5.7	signal
212	Chronic Obstructive Pulmonary Disease	209	5.7	5.7	signal
213	Metabolic Encephalopathy	12	5.6	5.6	signal
214	Alcoholism	17	5.6	5.6	signal
215	Incorrect Product Administration Duration	79	5.5	5.5	signal
216	Post-traumatic Stress Disorder	26	5.5	5.5	signal
217	Lip Pain	11	5.4	5.4	signal
218	Musculoskeletal Chest Pain	59	5.4	5.4	signal
219	Anhedonia	100	5.3	5.4	signal
220	Non-cardiac Chest Pain	12	5.3	5.3	signal
221	Haematochezia	207	5.3	5.4	signal
222	Obsessive-compulsive Disorder	30	5.2	5.2	signal
223	Electrocardiogram Qrs Complex Prolonged	19	5.2	5.2	signal
224	Sputum Discoloured	35	5.2	5.2	signal
225	Accidental Overdose	134	5.2	5.2	signal
226	Arteriosclerosis	34	5.1	5.1	signal
227	Rash Morbilliform	10	5.1	5.1	signal
228	End Stage Renal Disease	66	5.1	5.1	signal
229	Toxicity To Various Agents	596	5.0	5.2	signal
230	Major Depression	26	5.0	5.0	signal
231	Product Administration Interrupted	27	5.0	5.0	signal
232	Gingivitis	19	5.0	5.0	signal
233	Overdose	762	5.0	5.2	signal
234	Miosis	28	5.0	5.0	signal
235	Eosinophil Count Increased	29	4.9	4.9	signal
236	Lung Cancer Metastatic	10	4.9	4.9	signal
237	Pulmonary Congestion	46	4.9	4.9	signal
238	Infusion Related Reaction	228	4.9	4.9	signal
239	Left Ventricular Dysfunction	23	4.9	4.9	signal
240	Schizophrenia	41	4.8	4.8	signal
241	Brain Oedema	42	4.7	4.7	signal
242	Partial Seizures	17	4.6	4.6	signal
243	Throat Cancer	14	4.6	4.6	signal
244	Wrong Technique In Drug Usage Process	121	4.6	4.7	signal
245	Mastication Disorder	10	4.6	4.6	signal
246	Tearfulness	14	4.6	4.6	signal
247	Ischaemic Cardiomyopathy	10	4.5	4.6	signal
248	Hallucination, Auditory	51	4.5	4.5	signal
249	Troponin Increased	24	4.5	4.5	signal
250	Depression Suicidal	11	4.5	4.5	signal
251	Self-medication	13	4.5	4.5	signal
252	Pulmonary Oedema	141	4.4	4.5	signal
253	Stillbirth	15	4.3	4.4	signal
254	Dermatitis Contact	35	4.3	4.4	signal
255	Cardiopulmonary Failure	12	4.3	4.3	signal
256	Dyspepsia	297	4.3	4.3	signal
257	Myoclonus	36	4.3	4.3	signal
258	Peptic Ulcer	10	4.2	4.2	signal
259	Cardiomegaly	37	4.2	4.2	signal
260	Drug Diversion	17	4.2	4.2	signal
261	Atrioventricular Block Second Degree	9	4.2	4.2	signal
262	Product Quality Issue	398	4.2	4.2	signal
263	Spinal Osteoarthritis	26	4.1	4.2	signal
264	Hiccups	24	4.1	4.1	signal
265	Affective Disorder	23	4.1	4.1	signal
266	Enterococcal Infection	14	4.1	4.1	signal
267	Gingival Pain	23	4.1	4.1	signal
268	Tachyphrenia	10	4.1	4.1	signal
269	Toothache	52	4.0	4.1	signal
270	Necrotising Fasciitis	10	4.0	4.0	signal
271	Pulmonary Mass	42	4.0	4.0	signal
272	Multiple Injuries	18	4.0	4.0	signal
273	Drug Dependence	459	4.0	4.1	signal
274	Chronic Kidney Disease	216	4.0	4.0	signal
275	Oropharyngeal Discomfort	25	3.9	3.9	signal
276	Product Dose Omission	185	3.9	4.0	signal
277	Expired Drug Administered	14	3.9	3.9	signal
278	Inguinal Hernia	17	3.9	3.9	signal
279	Monocyte Count Increased	10	3.9	3.9	signal
280	Renal Tubular Necrosis	27	3.9	3.9	signal
281	Feeling Jittery	52	3.8	3.8	signal
282	Exposure During Pregnancy	169	3.8	3.9	signal
283	Hypomania	10	3.8	3.8	signal
284	Serotonin Syndrome	51	3.8	3.8	signal
285	Mental Status Changes	74	3.7	3.8	signal
286	Underdose	194	3.7	3.8	signal
287	Myocarditis	30	3.7	3.7	signal
288	Withdrawal Syndrome	110	3.7	3.7	signal
289	Unresponsive To Stimuli	67	3.7	3.7	signal
290	Wheezing	154	3.7	3.7	signal
291	Salivary Hypersecretion	26	3.7	3.7	signal
292	Abscess Limb	11	3.6	3.6	signal
293	Mitral Valve Incompetence	29	3.6	3.6	signal
294	Lung Neoplasm	11	3.6	3.6	signal
295	Malnutrition	28	3.5	3.6	signal
296	Iron Deficiency	11	3.5	3.5	signal
297	Exercise Tolerance Decreased	14	3.5	3.5	signal
298	Peripheral Ischaemia	10	3.4	3.4	signal
299	Concomitant Disease Aggravated	15	3.4	3.4	signal
300	Hypoxia	84	3.4	3.4	signal
301	Pre-existing Condition Improved	15	3.3	3.3	signal
302	Irritability	143	3.3	3.4	signal
303	Deafness Unilateral	13	3.3	3.3	signal
304	Osteopenia	36	3.3	3.3	signal
305	Panic Reaction	17	3.3	3.3	signal
306	Psychomotor Hyperactivity	39	3.3	3.3	signal
307	Gestational Diabetes	11	3.3	3.3	signal
308	Loss Of Libido	21	3.3	3.3	signal
309	Hyperlipidaemia	28	3.3	3.3	signal
310	Anger	79	3.3	3.3	signal
311	Ischaemic Stroke	41	3.2	3.2	signal
312	Electrocardiogram Abnormal	18	3.2	3.2	signal
313	Tricuspid Valve Incompetence	18	3.2	3.2	signal
314	Drug Interaction	360	3.2	3.2	signal
315	Oliguria	14	3.2	3.2	signal
316	Thermal Burn	16	3.2	3.2	signal
317	Paranoia	39	3.2	3.2	signal
318	Social Avoidant Behaviour	13	3.2	3.2	signal
319	Haemoglobin Increased	10	3.1	3.1	signal
320	Shock Haemorrhagic	18	3.1	3.1	signal
321	Candidiasis	9	3.1	3.1	signal
322	Sedation	57	3.1	3.1	signal
323	Cardiac Murmur	19	3.1	3.1	signal
324	Restlessness	80	3.1	3.1	signal
325	Coronary Artery Stenosis	11	3.1	3.1	signal
326	Drug Level Increased	36	3.1	3.1	signal
327	Delirium	75	3.1	3.1	signal
328	Drug Withdrawal Syndrome	190	3.0	3.0	signal
329	Neutrophil Count Increased	22	3.0	3.0	signal
330	Tension	13	3.0	3.0	signal
331	Respiratory Arrest	59	3.0	3.0	signal
332	Panic Attack	77	3.0	3.0	signal
333	Pulse Absent	10	2.9	3.0	signal
334	Oral Discomfort	29	2.9	2.9	signal
335	Expired Product Administered	69	2.9	2.9	signal
336	Nystagmus	11	2.9	2.9	signal
337	Obesity	33	2.9	2.9	signal
338	Psychotic Disorder	61	2.9	2.9	signal
339	Nerve Injury	23	2.9	2.9	signal
340	Tooth Abscess	21	2.9	2.9	signal
341	Suicidal Ideation	188	2.9	2.9	signal
342	Sleep Apnoea Syndrome	39	2.9	2.9	signal
343	Energy Increased	12	2.8	2.8	signal
344	Depressed Mood	106	2.8	2.8	signal
345	Intentional Product Misuse	174	2.8	2.8	signal
346	Tooth Fracture	22	2.8	2.8	signal
347	Platelet Count Increased	26	2.8	2.8	signal
348	Hepatic Steatosis	37	2.8	2.8	signal
349	Respiratory Failure	145	2.8	2.8	signal
350	Acute Respiratory Failure	38	2.8	2.8	signal
351	Increased Appetite	37	2.8	2.8	signal
352	Necrosis	11	2.8	2.8	signal
353	Endocarditis	10	2.7	2.8	signal
354	Bundle Branch Block Right	9	2.7	2.7	signal
355	Mood Swings	62	2.7	2.7	signal
356	Ataxia	23	2.7	2.7	signal
357	Dependence	107	2.7	2.7	signal
358	Cerebral Ischaemia	10	2.7	2.7	signal
359	Productive Cough	91	2.7	2.7	signal
360	Respiratory Distress	53	2.7	2.7	signal
361	Completed Suicide	161	2.7	2.7	signal
362	Constipation	411	2.7	2.7	signal
363	Vasculitis	22	2.7	2.7	signal
364	Nervousness	99	2.7	2.7	signal
365	Tachycardia	167	2.6	2.7	signal
366	Loss Of Consciousness	241	2.6	2.7	signal
367	Tubulointerstitial Nephritis	35	2.6	2.6	signal
368	Tooth Loss	39	2.6	2.6	signal
369	Electrocardiogram Qt Prolonged	67	2.6	2.6	signal
370	Apathy	27	2.6	2.6	signal
371	Refusal Of Treatment By Patient	12	2.6	2.6	signal
372	Type 1 Diabetes Mellitus	11	2.6	2.6	signal
373	Myocardial Ischaemia	21	2.6	2.6	signal
374	Somnambulism	12	2.6	2.6	signal
375	Agitation	134	2.6	2.6	signal
376	Prothrombin Time Prolonged	11	2.6	2.6	signal
377	Neutropenic Sepsis	13	2.6	2.6	signal
378	Dyspnoea Exertional	68	2.5	2.6	signal
379	Anxiety	516	2.5	2.6	signal
380	Dysarthria	68	2.5	2.6	signal
381	Pharyngeal Oedema	28	2.5	2.5	signal
382	Sneezing	40	2.5	2.5	signal
383	Torsade De Pointes	14	2.5	2.5	signal
384	Cyanosis	28	2.5	2.5	signal
385	Arterial Occlusive Disease	14	2.5	2.5	signal
386	Blood Sodium Decreased	33	2.5	2.5	signal
387	Drooling	12	2.5	2.5	signal
388	Poisoning	22	2.5	2.5	signal
389	Oral Pain	39	2.4	2.4	signal
390	Drug Administration Error	54	2.4	2.4	signal
391	Acute Kidney Injury	264	2.4	2.5	signal
392	Palpitations	202	2.4	2.4	signal
393	Upper Gastrointestinal Haemorrhage	29	2.4	2.4	signal
394	Mania	28	2.4	2.4	signal
395	Hiatus Hernia	22	2.4	2.4	signal
396	Clostridium Difficile Colitis	18	2.4	2.4	signal
397	Brain Injury	17	2.4	2.4	signal
398	Anal Incontinence	15	2.4	2.4	signal
399	Inappropriate Antidiuretic Hormone Secretion	17	2.3	2.4	signal
400	Diverticulum	12	2.3	2.3	signal
401	Renal Injury	50	2.3	2.3	signal
402	Aspiration	18	2.3	2.3	signal
403	Skin Plaque	14	2.3	2.3	signal
404	Rib Fracture	34	2.3	2.3	signal
405	Mental Disorder	72	2.3	2.3	signal
406	Electrolyte Imbalance	19	2.3	2.3	signal
407	Hallucination	123	2.3	2.3	signal
408	Abortion Spontaneous	66	2.3	2.3	signal
409	Coma	78	2.3	2.3	signal
410	Renal Cyst	13	2.3	2.3	signal
411	Eructation	31	2.3	2.3	signal
412	Ventricular Tachycardia	27	2.3	2.3	signal
413	Infusion Site Swelling	10	2.3	2.3	signal
414	Convulsion	94	2.3	2.3	signal
415	Aggression	81	2.3	2.3	signal
416	Oxygen Saturation Decreased	90	2.3	2.3	signal
417	Intervertebral Disc Degeneration	15	2.3	2.3	signal
418	Sensory Loss	13	2.3	2.3	signal
419	Gingival Bleeding	22	2.3	2.3	signal
420	Pneumonia Aspiration	40	2.3	2.3	signal
421	Leukocytosis	29	2.3	2.3	signal
422	Cold Sweat	28	2.2	2.2	signal
423	Abnormal Faeces	13	2.2	2.2	signal
424	Hyperhidrosis	204	2.2	2.2	signal
425	Anaemia	300	2.2	2.2	signal
426	Abdominal Pain	365	2.2	2.2	signal
427	Hypercholesterolaemia	15	2.2	2.2	signal
428	Live Birth	13	2.2	2.2	signal
429	Acute Coronary Syndrome	13	2.2	2.2	signal
430	Disseminated Intravascular Coagulation	22	2.2	2.2	signal
431	Sleep Disorder	109	2.2	2.2	signal
432	Cardiomyopathy	23	2.2	2.2	signal
433	Erythema	318	2.2	2.2	signal
434	Atrial Septal Defect	13	2.2	2.2	signal
435	Coronary Artery Occlusion	21	2.1	2.1	signal
436	Hyperkalaemia	53	2.1	2.1	signal
437	Blood Albumin Decreased	12	2.1	2.1	signal
438	Incontinence	16	2.1	2.1	signal
439	Muscle Strain	13	2.1	2.1	signal
440	Blood Creatine Phosphokinase Increased	44	2.1	2.1	signal
441	Hypokalaemia	69	2.1	2.1	signal
442	Prescribed Overdose	29	2.1	2.1	signal
443	Cardiac Arrest	124	2.1	2.1	signal
444	Skin Reaction	21	2.1	2.1	signal
445	Rash Maculo-papular	33	2.1	2.1	signal
446	Renal Failure	199	2.1	2.1	signal
447	Lower Gastrointestinal Haemorrhage	11	2.1	2.1	signal
448	Ejection Fraction Decreased	23	2.1	2.1	signal
449	Hepatitis C	18	2.1	2.1	signal
450	Decubitus Ulcer	12	2.1	2.1	signal
451	Maternal Exposure Before Pregnancy	10	2.1	2.1	signal
452	Lymphocyte Count Decreased	26	2.1	2.1	signal
453	Encephalopathy	36	2.1	2.1	signal
454	Depression	335	2.1	2.1	signal
455	Accidental Exposure To Product By Child	10	2.1	2.1	signal
456	Septic Shock	63	2.1	2.1	signal
457	Angina Pectoris	42	2.0	2.1	signal
458	Libido Decreased	18	2.0	2.0	signal
459	Acute Myocardial Infarction	43	2.0	2.0	signal
460	Drug Exposure During Pregnancy	50	2.0	2.0	signal
461	Poor Quality Sleep	31	2.0	2.0	signal
462	Cellulitis	73	2.0	2.0	signal
463	Bacteraemia	17	2.0	2.0	signal
464	Product Use Issue	270	2.0	2.1	signal
465	Mental Impairment	35	2.0	2.0	signal
466	Papule	10	2.0	2.0	signal
467	Vitamin D Deficiency	14	2.0	2.0	signal
468	Formication	10	2.0	2.0	signal
469	Osteoporosis	59	2.0	2.0	signal
470	Injury	101	2.0	2.0	signal
471	Product Availability Issue	32	2.0	2.0	signal
472	Depressed Level Of Consciousness	56	2.0	2.0	no signal
473	Chest Pain	263	2.0	2.0	no signal
474	Pruritus Generalised	31	2.0	2.0	no signal
475	Blood Triglycerides Increased	25	2.0	2.0	no signal
476	Urosepsis	13	2.0	2.0	no signal
477	Hyperglycaemia	51	2.0	2.0	no signal
478	Cardio-respiratory Arrest	59	2.0	2.0	no signal
479	Product Preparation Error	29	2.0	2.0	no signal
480	Intentional Overdose	89	2.0	2.0	no signal
481	Insomnia	371	2.0	2.0	no signal
482	Personality Change	13	2.0	2.0	no signal
483	Blood Magnesium Decreased	12	2.0	2.0	no signal
484	Hallucination, Visual	29	1.9	1.9	no signal
485	Wrong Technique In Product Usage Process	279	1.9	2.0	no signal
486	Drug Dose Omission	231	1.9	2.0	no signal
487	Tremor	229	1.9	2.0	no signal
488	Product Administered At Inappropriate Site	25	1.9	1.9	no signal
489	Pain In Jaw	39	1.9	1.9	no signal
490	Fear	37	1.9	1.9	no signal
491	Mouth Haemorrhage	10	1.9	1.9	no signal
492	Sleep Disorder Due To A General Medical Condition	22	1.9	1.9	no signal
493	Gastrooesophageal Reflux Disease	109	1.9	1.9	no signal
494	Face Oedema	23	1.9	1.9	no signal
495	Haematocrit Decreased	27	1.9	1.9	no signal
496	Dry Mouth	109	1.9	1.9	no signal
497	Asphyxia	11	1.9	1.9	no signal
498	Neuroleptic Malignant Syndrome	16	1.9	1.9	no signal
499	Muscle Rigidity	16	1.9	1.9	no signal
500	Pregnancy	27	1.9	1.9	no signal
501	Sinus Congestion	18	1.9	1.9	no signal
502	Hyperaesthesia	11	1.9	1.9	no signal
503	Confusional State	215	1.9	1.9	no signal
504	Mydriasis	17	1.9	1.9	no signal
505	Haemoptysis	37	1.9	1.9	no signal
506	Heart Rate Increased	131	1.9	1.9	no signal
507	Emotional Disorder	41	1.9	1.9	no signal
508	Malaise	579	1.9	1.9	no signal
509	Weight Decreased	367	1.8	1.9	no signal
510	Spinal Compression Fracture	11	1.8	1.8	no signal
511	Body Temperature Decreased	13	1.8	1.8	no signal
512	Abdominal Distension	136	1.8	1.8	no signal
513	Stress	94	1.8	1.8	no signal
514	Respiratory Depression	16	1.8	1.8	no signal
515	Small Intestinal Obstruction	16	1.8	1.8	no signal
516	Nausea	1,020	1.8	1.9	no signal
517	Poisoning Deliberate	12	1.8	1.8	no signal
518	Tooth Infection	17	1.8	1.8	no signal
519	Crying	47	1.8	1.8	no signal
520	Pallor	35	1.8	1.8	no signal
521	Scar	22	1.8	1.8	no signal
522	Hypothermia	13	1.8	1.8	no signal
523	Thinking Abnormal	24	1.8	1.8	no signal
524	Grand Mal Convulsion	12	1.8	1.8	no signal
525	Abnormal Behaviour	51	1.8	1.8	no signal
526	Photosensitivity Reaction	21	1.8	1.8	no signal
527	Heart Rate Irregular	29	1.8	1.8	no signal
528	Asthma	143	1.8	1.8	no signal
529	C-reactive Protein Increased	46	1.8	1.8	no signal
530	Spinal Disorder	12	1.8	1.8	no signal
531	Oropharyngeal Pain	117	1.8	1.8	no signal
532	Eating Disorder	27	1.8	1.8	no signal
533	Pneumothorax	20	1.8	1.8	no signal
534	Cardiogenic Shock	18	1.8	1.8	no signal
535	Disorientation	50	1.8	1.8	no signal
536	Disturbance In Attention	68	1.8	1.8	no signal
537	Febrile Neutropenia	83	1.8	1.8	no signal
538	Ventricular Extrasystoles	13	1.8	1.8	no signal
539	Coronary Artery Disease	38	1.8	1.8	no signal
540	Nocturia	15	1.7	1.7	no signal
541	Respiratory Rate Increased	11	1.7	1.7	no signal
542	Lung Infiltration	11	1.7	1.7	no signal
543	Scab	14	1.7	1.7	no signal
544	Circulatory Collapse	21	1.7	1.7	no signal
545	Bronchitis	91	1.7	1.7	no signal
546	Musculoskeletal Discomfort	21	1.7	1.7	no signal
547	Upper-airway Cough Syndrome	10	1.7	1.7	no signal
548	Polyuria	10	1.7	1.7	no signal
549	Anaphylactic Reaction	67	1.7	1.7	no signal
550	Osteomyelitis	22	1.7	1.7	no signal
551	Decreased Activity	13	1.7	1.7	no signal
552	Skin Lesion	33	1.7	1.7	no signal
553	Cardiovascular Disorder	31	1.7	1.7	no signal
554	Pancreatitis Acute	27	1.7	1.7	no signal
555	Foot Fracture	23	1.7	1.7	no signal
556	Developmental Delay	11	1.7	1.7	no signal
557	Renal Failure Acute	52	1.7	1.7	no signal
558	Orthostatic Hypotension	21	1.7	1.7	no signal
559	Metabolic Acidosis	38	1.7	1.7	no signal
560	Hypotension	240	1.7	1.7	no signal
561	Brain Neoplasm	11	1.7	1.7	no signal
562	Hypotonia	12	1.7	1.7	no signal
563	Fibromyalgia	29	1.7	1.7	no signal
564	Intentional Self-injury	24	1.7	1.7	no signal
565	Hypersomnia	34	1.7	1.7	no signal
566	Toxic Skin Eruption	12	1.7	1.7	no signal
567	Lethargy	68	1.7	1.7	no signal
568	Pleural Effusion	72	1.7	1.7	no signal
569	Pyrexia	408	1.7	1.7	no signal
570	Akathisia	16	1.6	1.6	no signal
571	Head Injury	37	1.6	1.6	no signal
572	Blood Count Abnormal	18	1.6	1.6	no signal
573	Road Traffic Accident	49	1.6	1.6	no signal
574	Hyperbilirubinaemia	12	1.6	1.6	no signal
575	Tooth Disorder	26	1.6	1.6	no signal
576	Atrioventricular Block	9	1.6	1.6	no signal
577	Scratch	12	1.6	1.6	no signal
578	Anuria	10	1.6	1.6	no signal
579	Drug Ineffective	1,517	1.6	1.7	no signal
580	Suicide Attempt	70	1.6	1.6	no signal
581	Impaired Driving Ability	13	1.6	1.6	no signal
582	Gastritis	30	1.6	1.6	no signal
583	Haematemesis	29	1.6	1.6	no signal
584	Intervertebral Disc Protrusion	25	1.6	1.6	no signal
585	Hyponatraemia	64	1.6	1.6	no signal
586	Emotional Distress	138	1.6	1.6	no signal
587	Respiratory Disorder	34	1.6	1.6	no signal
588	Blood Pressure Decreased	75	1.6	1.6	no signal
589	Retching	24	1.6	1.6	no signal
590	Neck Pain	63	1.6	1.6	no signal
591	Muscle Twitching	26	1.6	1.6	no signal
592	Blister	63	1.6	1.6	no signal
593	Diabetes Mellitus	86	1.6	1.6	no signal
594	Headache	702	1.6	1.6	no signal
595	Swollen Tongue	35	1.6	1.6	no signal
596	Feeling Abnormal	269	1.6	1.6	no signal
597	Quality Of Life Decreased	15	1.6	1.6	no signal
598	Hepatomegaly	11	1.6	1.6	no signal
599	Muscle Atrophy	14	1.6	1.6	no signal
600	Blood Potassium Increased	18	1.6	1.6	no signal
601	Syncope	111	1.6	1.6	no signal
602	Tachypnoea	15	1.6	1.6	no signal
603	Faeces Discoloured	24	1.6	1.6	no signal
604	Dizziness	550	1.6	1.6	no signal
605	Cytokine Release Syndrome	21	1.5	1.6	no signal
606	Blood Creatinine Increased	72	1.5	1.6	no signal
607	Chest Discomfort	112	1.5	1.5	no signal
608	Shock	25	1.5	1.5	no signal
609	Pulmonary Embolism	104	1.5	1.5	no signal
610	Inappropriate Schedule Of Drug Administration	78	1.5	1.5	no signal
611	Bursitis	13	1.5	1.5	no signal
612	Temperature Intolerance	11	1.5	1.5	no signal
613	Bone Density Decreased	34	1.5	1.5	no signal
614	Dyspnoea	607	1.5	1.5	no signal
615	Blood Cholesterol Increased	50	1.5	1.5	no signal
616	Blood Pressure Systolic Increased	21	1.5	1.5	no signal
617	Mass	15	1.5	1.5	no signal
618	Intentional Product Use Issue	94	1.5	1.5	no signal
619	Speech Disorder	56	1.5	1.5	no signal
620	Rash Generalised	28	1.5	1.5	no signal
621	Hepatic Cytolysis	13	1.5	1.5	no signal
622	Status Epilepticus	12	1.5	1.5	no signal
623	Generalised Oedema	13	1.5	1.5	no signal
624	Tenderness	11	1.5	1.5	no signal
625	Pulmonary Hypertension	22	1.5	1.5	no signal
626	Muscle Tightness	17	1.5	1.5	no signal
627	Somnolence	210	1.5	1.5	no signal
628	Subdural Haematoma	15	1.5	1.5	no signal
629	Restless Legs Syndrome	19	1.5	1.5	no signal
630	Impaired Quality Of Life	15	1.5	1.5	no signal
631	Dizziness Postural	10	1.5	1.5	no signal
632	Neutropenia	141	1.5	1.5	no signal
633	Pneumonitis	28	1.5	1.5	no signal
634	Affect Lability	10	1.5	1.5	no signal
635	Paraesthesia	163	1.5	1.5	no signal
636	Sinus Bradycardia	10	1.5	1.5	no signal
637	Hypokinesia	15	1.5	1.5	no signal
638	Thrombotic Microangiopathy	10	1.5	1.5	no signal
639	Ankle Fracture	16	1.5	1.5	no signal
640	Blood Potassium Decreased	31	1.4	1.4	no signal
641	Eosinophilia	18	1.4	1.4	no signal
642	Acute Hepatic Failure	14	1.4	1.4	no signal
643	Body Temperature Increased	21	1.4	1.4	no signal
644	Haemorrhoids	20	1.4	1.4	no signal
645	Hypersensitivity	188	1.4	1.4	no signal
646	Hypertension	215	1.4	1.4	no signal
647	Rotator Cuff Syndrome	13	1.4	1.4	no signal
648	Skin Ulcer	26	1.4	1.4	no signal
649	Ulcer	16	1.4	1.4	no signal
650	Product Physical Issue	20	1.4	1.4	no signal
651	Blood Pressure Increased	153	1.4	1.4	no signal
652	Carpal Tunnel Syndrome	14	1.4	1.4	no signal
653	Myocardial Infarction	175	1.4	1.4	no signal
654	Presyncope	24	1.4	1.4	no signal
655	Seasonal Allergy	14	1.4	1.4	no signal
656	Hypoglycaemia	48	1.4	1.4	no signal
657	Bone Loss	15	1.4	1.4	no signal
658	Intestinal Obstruction	37	1.4	1.4	no signal
659	Glossodynia	22	1.4	1.4	no signal
660	Initial Insomnia	10	1.4	1.4	no signal
661	Choking	19	1.4	1.4	no signal
662	Drug Level Decreased	10	1.4	1.4	no signal
663	Increased Tendency To Bruise	9	1.4	1.4	no signal
664	Eye Swelling	36	1.4	1.4	no signal
665	Product Packaging Issue	9	1.4	1.4	no signal
666	Delusion	15	1.4	1.4	no signal
667	Middle Insomnia	18	1.4	1.4	no signal
668	Product Taste Abnormal	13	1.4	1.4	no signal
669	Gastrointestinal Haemorrhage	81	1.4	1.4	no signal
670	Acute Respiratory Distress Syndrome	17	1.4	1.4	no signal
671	Gastroenteritis	14	1.4	1.4	no signal
672	Bradycardia	51	1.3	1.4	no signal
673	Nephropathy	9	1.3	1.3	no signal
674	Pericardial Effusion	22	1.3	1.3	no signal
675	Therapeutic Response Unexpected	43	1.3	1.3	no signal
676	Epilepsy	29	1.3	1.3	no signal
677	Seizure	109	1.3	1.3	no signal
678	Type 2 Diabetes Mellitus	32	1.3	1.3	no signal
679	Renal Pain	10	1.3	1.3	no signal
680	Laceration	9	1.3	1.3	no signal
681	Pain	580	1.3	1.3	no signal
682	Sepsis	105	1.3	1.3	no signal
683	Hemiparesis	16	1.3	1.3	no signal
684	International Normalised Ratio Increased	27	1.3	1.3	no signal
685	Rhabdomyolysis	39	1.3	1.3	no signal
686	Impaired Work Ability	20	1.3	1.3	no signal
687	Contraindicated Product Administered	28	1.3	1.3	no signal
688	Vomiting	435	1.3	1.3	no signal
689	Dystonia	18	1.3	1.3	no signal
690	Adrenal Insufficiency	11	1.3	1.3	no signal
691	Flatulence	52	1.3	1.3	no signal
692	Anorexia	12	1.3	1.3	no signal
693	Generalised Tonic-clonic Seizure	15	1.3	1.3	no signal
694	Hepatocellular Injury	13	1.3	1.3	no signal
695	Hypothyroidism	29	1.3	1.3	no signal
696	White Blood Cell Count Increased	35	1.3	1.3	no signal
697	Bronchospasm	13	1.3	1.3	no signal
698	Swelling Face	59	1.3	1.3	no signal
699	Nasal Congestion	53	1.3	1.3	no signal
700	Transaminases Increased	20	1.3	1.3	no signal
701	Lung Disorder	44	1.3	1.3	no signal
702	Migraine	85	1.3	1.3	no signal
703	Ileus	11	1.3	1.3	no signal
704	Skin Irritation	41	1.3	1.3	no signal
705	Skin Discolouration	41	1.3	1.3	no signal
706	Cholestasis	17	1.3	1.3	no signal
707	Dry Throat	9	1.2	1.2	no signal
708	Pneumonia	286	1.2	1.2	no signal
709	Cholelithiasis	29	1.2	1.2	no signal
710	Loss Of Personal Independence In Daily Activities	42	1.2	1.2	no signal
711	Medication Error	49	1.2	1.2	no signal
712	Pharyngitis	11	1.2	1.2	no signal
713	Heart Rate Decreased	31	1.2	1.2	no signal
714	Urinary Incontinence	26	1.2	1.2	no signal
715	Deep Vein Thrombosis	57	1.2	1.2	no signal
716	Lung Neoplasm Malignant	36	1.2	1.2	no signal
717	Urinary Retention	29	1.2	1.2	no signal
718	Iron Deficiency Anaemia	8	1.2	1.2	no signal
719	Neoplasm	10	1.2	1.2	no signal
720	Product Odour Abnormal	9	1.2	1.2	no signal
721	Petechiae	9	1.2	1.2	no signal
722	Gastric Haemorrhage	10	1.2	1.2	no signal
723	Cough	241	1.2	1.2	no signal
724	Drug Reaction With Eosinophilia And Systemic Symptoms	22	1.2	1.2	no signal
725	Amnesia	56	1.2	1.2	no signal
726	Transient Ischaemic Attack	29	1.2	1.2	no signal
727	Diarrhoea Haemorrhagic	8	1.2	1.2	no signal
728	Inappropriate Schedule Of Product Administration	151	1.2	1.2	no signal
729	Weight Increased	189	1.2	1.2	no signal
730	Dehydration	113	1.2	1.2	no signal
731	Diabetes Mellitus Inadequate Control	15	1.2	1.2	no signal
732	Mucosal Inflammation	22	1.2	1.2	no signal
733	Lower Limb Fracture	16	1.2	1.2	no signal
734	Incorrect Dose Administered	188	1.2	1.2	no signal
735	Oedema Peripheral	102	1.2	1.2	no signal
736	Skin Laceration	9	1.2	1.2	no signal
737	Back Injury	9	1.2	1.2	no signal
738	Laryngitis	9	1.2	1.2	no signal
739	Wound	23	1.2	1.2	no signal
740	Liver Injury	20	1.2	1.2	no signal
741	Feeling Cold	23	1.2	1.2	no signal
742	Cerebral Infarction	20	1.1	1.1	no signal
743	Respiratory Tract Congestion	13	1.1	1.1	no signal
744	Angioedema	36	1.1	1.1	no signal
745	Erectile Dysfunction	21	1.1	1.1	no signal
746	Blood Bilirubin Increased	22	1.1	1.1	no signal
747	Hospice Care	8	1.1	1.1	no signal
748	Agranulocytosis	15	1.1	1.1	no signal
749	Hypercalcaemia	10	1.1	1.1	no signal
750	Disability	16	1.1	1.1	no signal
751	Diplopia	21	1.1	1.1	no signal
752	Hypoaesthesia	121	1.1	1.1	no signal
753	Sinus Disorder	16	1.1	1.1	no signal
754	Dysgeusia	60	1.1	1.1	no signal
755	Leukopenia	40	1.1	1.1	no signal
756	Upper Limb Fracture	16	1.1	1.1	no signal
757	Burning Sensation	56	1.1	1.1	no signal
758	Rash Pruritic	43	1.1	1.1	no signal
759	Hypoaesthesia Oral	12	1.1	1.1	no signal
760	Decreased Appetite	184	1.1	1.1	no signal
761	Gastric Ulcer	15	1.1	1.1	no signal
762	Multiple Fractures	13	1.1	1.1	no signal
763	Subarachnoid Haemorrhage	8	1.1	1.1	no signal
764	Infusion Site Pain	10	1.1	1.1	no signal
765	Feeling Hot	48	1.1	1.1	no signal
766	Ear Discomfort	8	1.1	1.1	no signal
767	Lactic Acidosis	25	1.1	1.1	no signal
768	Asthenia	292	1.1	1.1	no signal
769	Rash Macular	27	1.1	1.1	no signal
770	Dermatitis	16	1.1	1.1	no signal
771	Swelling	72	1.1	1.1	no signal
772	Drug Prescribing Error	15	1.1	1.1	no signal
773	Back Pain	178	1.1	1.1	no signal
774	Blood Alkaline Phosphatase Increased	19	1.1	1.1	no signal
775	Thrombocytopenia	85	1.1	1.1	no signal
776	Hospitalisation	116	1.1	1.1	no signal
777	Dysuria	28	1.1	1.1	no signal
778	Ageusia	19	1.1	1.1	no signal
779	Pharmaceutical Product Complaint	20	1.1	1.1	no signal
780	Staphylococcal Infection	25	1.1	1.1	no signal
781	Osteoarthritis	32	1.1	1.1	no signal
782	Diabetic Ketoacidosis	18	1.1	1.1	no signal
783	Lower Respiratory Tract Infection	34	1.1	1.1	no signal
784	Hepatic Encephalopathy	7	1.1	1.1	no signal
785	Sudden Death	8	1.1	1.1	no signal
786	Flank Pain	7	1.1	1.1	no signal
787	Deformity	7	1.0	1.0	no signal
788	Drug Hypersensitivity	144	1.0	1.0	no signal
789	Cerebrovascular Accident	126	1.0	1.0	no signal
790	Haemoglobin Decreased	76	1.0	1.0	no signal
791	Mood Altered	20	1.0	1.0	no signal
792	Fall	244	1.0	1.0	no signal
793	Bone Marrow Failure	15	1.0	1.0	no signal
794	Pulmonary Fibrosis	14	1.0	1.0	no signal
795	Therapy Partial Responder	11	1.0	1.0	no signal
796	Thirst	13	1.0	1.0	no signal
797	Vaginal Haemorrhage	31	1.0	1.0	no signal
798	Blood Glucose Fluctuation	8	1.0	1.0	no signal
799	Tendon Rupture	9	1.0	1.0	no signal
800	Glaucoma	14	1.0	1.0	no signal
801	Peripheral Coldness	10	1.0	1.0	no signal
802	Dermatitis Allergic	9	1.0	1.0	no signal
803	Skin Disorder	24	1.0	1.0	no signal
804	Hypomagnesaemia	10	1.0	1.0	no signal
805	Cystitis	23	1.0	1.0	no signal
806	Liver Function Test Abnormal	21	1.0	1.0	no signal
807	Vision Blurred	98	1.0	1.0	no signal
808	Hip Fracture	23	1.0	1.0	no signal
809	Balance Disorder	62	1.0	1.0	no signal
810	Throat Irritation	32	1.0	1.0	no signal
811	Upper Respiratory Tract Infection	33	1.0	1.0	no signal
812	Pain In Extremity	211	1.0	1.0	no signal
813	Incorrect Route Of Product Administration	12	1.0	1.0	no signal
814	Kidney Infection	14	1.0	1.0	no signal
815	Mouth Ulceration	15	1.0	1.0	no signal
816	Blood Urea Increased	12	1.0	1.0	no signal
817	Rash Papular	16	1.0	1.0	no signal
818	Ligament Sprain	7	1.0	1.0	no signal
819	Bone Disorder	13	1.0	1.0	no signal
820	Rash	306	1.0	1.0	no signal
821	Impaired Gastric Emptying	9	1.0	1.0	no signal
822	Micturition Urgency	8	1.0	1.0	no signal
823	Throat Tightness	19	1.0	1.0	no signal
824	Pancreatitis	37	1.0	1.0	no signal
825	Hepatic Cirrhosis	13	1.0	1.0	no signal
826	Hepatic Failure	21	1.0	1.0	no signal
827	Arrhythmia	33	1.0	1.0	no signal
828	Metastases To Lung	8	1.0	1.0	no signal
829	Motor Dysfunction	7	1.0	1.0	no signal
830	Dyskinesia	28	1.0	1.0	no signal
831	Incorrect Route Of Drug Administration	25	1.0	1.0	no signal
832	Hypocalcaemia	13	1.0	1.0	no signal
833	Abdominal Discomfort	115	1.0	1.0	no signal
834	Diverticulitis	19	1.0	1.0	no signal
835	Sexual Dysfunction	8	1.0	1.0	no signal
836	Multi-organ Failure	12	1.0	1.0	no signal
837	Oedema	37	1.0	1.0	no signal
838	Splenomegaly	8	1.0	1.0	no signal
839	Sensory Disturbance	11	1.0	1.0	no signal
840	Head Discomfort	12	1.0	1.0	no signal
841	Extra Dose Administered	27	1.0	1.0	no signal
842	Hot Flush	51	1.0	1.0	no signal
843	Cholecystitis	8	0.9	0.9	no signal
844	Cardiac Failure	54	0.9	0.9	no signal
845	Cerebral Haemorrhage	24	0.9	0.9	no signal
846	Myalgia	114	0.9	0.9	no signal
847	Haematuria	23	0.9	0.9	no signal
848	Wrist Fracture	8	0.9	0.9	no signal
849	Epistaxis	50	0.9	0.9	no signal
850	Joint Dislocation	7	0.9	0.9	no signal
851	Limb Injury	18	0.9	0.9	no signal
852	Coagulopathy	11	0.9	0.9	no signal
853	Localised Infection	16	0.9	0.9	no signal
854	Urticaria	110	0.9	0.9	no signal
855	Glomerular Filtration Rate Decreased	8	0.9	0.9	no signal
856	Gait Disturbance	126	0.9	0.9	no signal
857	Atrial Fibrillation	64	0.9	0.9	no signal
858	Dysphagia	62	0.9	0.9	no signal
859	Drug Administered At Inappropriate Site	7	0.9	0.9	no signal
860	Cardiac Failure Congestive	53	0.9	0.9	no signal
861	Haematoma	17	0.9	0.9	no signal
862	Abdominal Pain Upper	134	0.9	0.9	no signal
863	Spinal Fracture	13	0.9	0.9	no signal
864	Body Height Decreased	7	0.9	0.9	no signal
865	Wound Infection	7	0.9	0.9	no signal
866	Stomatitis	39	0.9	0.9	no signal
867	Oesophagitis	7	0.9	0.9	no signal
868	Gastrointestinal Pain	7	0.9	0.9	no signal
869	Drug Effect Less Than Expected	9	0.9	0.9	no signal
870	Off Label Use	553	0.9	0.9	no signal
871	Squamous Cell Carcinoma	6	0.9	0.9	no signal
872	Proteinuria	12	0.9	0.9	no signal
873	Drug Intolerance	61	0.9	0.9	no signal
874	Supraventricular Tachycardia	6	0.9	0.9	no signal
875	Abscess	10	0.9	0.9	no signal
876	Pruritus	237	0.9	0.9	no signal
877	Therapy Cessation	32	0.9	0.9	no signal
878	Condition Aggravated	189	0.9	0.9	no signal
879	Post Procedural Complication	12	0.9	0.9	no signal
880	Blood Pressure Fluctuation	15	0.9	0.9	no signal
881	Surgery	36	0.9	0.9	no signal
882	Lymphadenopathy	22	0.9	0.9	no signal
883	Anosmia	9	0.9	0.9	no signal
884	Ear Pain	12	0.9	0.9	no signal
885	Metastases To Bone	10	0.9	0.9	no signal
886	Deafness	16	0.9	0.9	no signal
887	Fluid Overload	9	0.9	0.9	no signal
888	Liver Function Test Increased	13	0.9	0.9	no signal
889	Bedridden	8	0.9	0.9	no signal
890	Joint Injury	13	0.9	0.9	no signal
891	Vertigo	37	0.9	0.9	no signal
892	General Physical Health Deterioration	69	0.8	0.8	no signal
893	Pollakiuria	25	0.8	0.8	no signal
894	Influenza	67	0.8	0.8	no signal
895	Joint Range Of Motion Decreased	8	0.8	0.8	no signal
896	Rash Erythematous	28	0.8	0.8	no signal
897	Activities Of Daily Living Impaired	12	0.8	0.8	no signal
898	Hunger	8	0.8	0.8	no signal
899	Contusion	57	0.8	0.8	no signal
900	Bacterial Infection	11	0.8	0.8	no signal
901	Abdominal Pain Lower	15	0.8	0.8	no signal
902	Fatigue	459	0.8	0.8	no signal
903	Sluggishness	6	0.8	0.8	no signal
904	Night Sweats	19	0.8	0.8	no signal
905	Movement Disorder	19	0.8	0.8	no signal
906	Memory Impairment	81	0.8	0.8	no signal
907	Musculoskeletal Pain	31	0.8	0.8	no signal
908	Tinnitus	27	0.8	0.8	no signal
909	Thrombosis	47	0.8	0.8	no signal
910	Dysstasia	17	0.8	0.8	no signal
911	Laboratory Test Abnormal	17	0.8	0.8	no signal
912	Urinary Tract Infection	98	0.8	0.8	no signal
913	Gastric Disorder	20	0.8	0.8	no signal
914	Hereditary Angioedema	6	0.8	0.8	no signal
915	Alanine Aminotransferase Increased	35	0.8	0.8	no signal
916	Coordination Abnormal	8	0.8	0.8	no signal
917	Blindness Unilateral	8	0.8	0.8	no signal
918	Drug Eruption	10	0.8	0.8	no signal
919	Muscle Spasms	104	0.8	0.8	no signal
920	Local Swelling	10	0.8	0.8	no signal
921	Red Blood Cell Count Decreased	16	0.8	0.8	no signal
922	Sinusitis	57	0.8	0.8	no signal
923	Clostridium Difficile Infection	12	0.8	0.8	no signal
924	Renal Impairment	46	0.8	0.8	no signal
925	Limb Discomfort	17	0.8	0.8	no signal
926	Pulmonary Arterial Hypertension	8	0.8	0.8	no signal
927	Intentional Dose Omission	15	0.8	0.8	no signal
928	Tuberculosis	7	0.8	0.8	no signal
929	Lip Swelling	18	0.8	0.8	no signal
930	Foot Deformity	6	0.8	0.8	no signal
931	Ventricular Fibrillation	6	0.8	0.8	no signal
932	Appendicitis	5	0.8	0.8	no signal
933	Erythema Multiforme	5	0.8	0.8	no signal
934	Photophobia	10	0.8	0.8	no signal
935	Fistula	6	0.7	0.7	no signal
936	Influenza Like Illness	44	0.7	0.7	no signal
937	Aphasia	16	0.7	0.7	no signal
938	Chills	62	0.7	0.7	no signal
939	Aspartate Aminotransferase Increased	28	0.7	0.7	no signal
940	Device Failure	8	0.7	0.7	no signal
941	Diarrhoea	339	0.7	0.7	no signal
942	Musculoskeletal Stiffness	46	0.7	0.7	no signal
943	Osteonecrosis Of Jaw	13	0.7	0.7	no signal
944	Thyroid Disorder	8	0.7	0.7	no signal
945	Eye Disorder	17	0.7	0.7	no signal
946	Illness	52	0.7	0.7	no signal
947	Cognitive Disorder	24	0.7	0.7	no signal
948	Peripheral Swelling	79	0.7	0.7	no signal
949	Irritable Bowel Syndrome	11	0.7	0.7	no signal
950	Eyelid Oedema	6	0.7	0.7	no signal
951	Hypophagia	13	0.7	0.7	no signal
952	Fungal Infection	17	0.7	0.7	no signal
953	Muscular Weakness	58	0.7	0.7	no signal
954	Ill-defined Disorder	31	0.7	0.7	no signal
955	Product Dose Omission Issue	145	0.7	0.7	no signal
956	Neuropathy Peripheral	48	0.7	0.7	no signal
957	Product Use In Unapproved Indication	123	0.7	0.7	no signal
958	Adverse Drug Reaction	45	0.7	0.7	no signal
959	Nephrolithiasis	23	0.7	0.7	no signal
960	Aphonia	7	0.7	0.7	no signal
961	Feeding Disorder	10	0.7	0.7	no signal
962	Prescribed Underdose	10	0.7	0.7	no signal
963	Product Administration Error	10	0.7	0.7	no signal
964	Melaena	11	0.7	0.7	no signal
965	Blood Glucose Decreased	24	0.7	0.7	no signal
966	Therapeutic Response Decreased	30	0.7	0.7	no signal
967	Stevens-johnson Syndrome	11	0.7	0.7	no signal
968	Ear Infection	13	0.7	0.7	no signal
969	Hypoacusis	21	0.7	0.7	no signal
970	Paralysis	7	0.7	0.7	no signal
971	Skin Haemorrhage	7	0.7	0.7	no signal
972	Tooth Extraction	6	0.7	0.7	no signal
973	Jaundice	13	0.7	0.7	no signal
974	Nervous System Disorder	15	0.7	0.7	no signal
975	Extrapyramidal Disorder	12	0.7	0.7	no signal
976	Fracture	9	0.7	0.7	no signal
977	Ocular Hyperaemia	22	0.7	0.7	no signal
978	Product Substitution Issue	27	0.7	0.7	no signal
979	Hernia	9	0.7	0.7	no signal
980	Toxic Epidermal Necrolysis	7	0.7	0.7	no signal
981	Unevaluable Event	35	0.6	0.6	no signal
982	Arthralgia	191	0.6	0.6	no signal
983	Bone Pain	27	0.6	0.6	no signal
984	Haemorrhage	48	0.6	0.6	no signal
985	Pulmonary Thrombosis	5	0.6	0.6	no signal
986	Joint Stiffness	12	0.6	0.6	no signal
987	Tardive Dyskinesia	13	0.6	0.6	no signal
988	Metastases To Liver	8	0.6	0.6	no signal
989	Blood Pressure Abnormal	9	0.6	0.6	no signal
990	Neuralgia	11	0.6	0.6	no signal
991	Cardiac Disorder	42	0.6	0.6	no signal
992	Gallbladder Disorder	8	0.6	0.6	no signal
993	Neutrophil Count Decreased	18	0.6	0.6	no signal
994	Lung Infection	7	0.6	0.6	no signal
995	Blood Glucose Increased	84	0.6	0.6	no signal
996	Chromaturia	10	0.6	0.6	no signal
997	Internal Haemorrhage	5	0.6	0.6	no signal
998	Skin Burning Sensation	31	0.6	0.6	no signal
999	Lacrimation Increased	13	0.6	0.6	no signal
1000	Rhinorrhoea	28	0.6	0.6	no signal
1001	Nerve Compression	4	0.6	0.6	no signal
1002	Adverse Event	40	0.6	0.6	no signal
1003	Dry Eye	21	0.6	0.6	no signal
1004	Arthritis	34	0.6	0.6	no signal
1005	Anaphylactic Shock	11	0.6	0.6	no signal
1006	Back Disorder	7	0.6	0.6	no signal
1007	Spinal Pain	5	0.6	0.6	no signal
1008	Leukaemia	4	0.6	0.6	no signal
1009	Visual Impairment	52	0.6	0.6	no signal
1010	Skin Exfoliation	35	0.6	0.6	no signal
1011	Flushing	43	0.6	0.6	no signal
1012	Accident	5	0.6	0.6	no signal
1013	Blood Urine Present	8	0.6	0.6	no signal
1014	Multiple Sclerosis Relapse	29	0.6	0.6	no signal
1015	Infection	60	0.6	0.6	no signal
1016	Therapy Change	4	0.6	0.6	no signal
1017	Parkinsonism	4	0.6	0.6	no signal
1018	Product Dose Omission In Error	11	0.6	0.6	no signal
1019	Renal Disorder	19	0.6	0.6	no signal
1020	Therapy Non-responder	18	0.6	0.6	no signal
1021	Cyst	5	0.6	0.6	no signal
1022	Ovarian Cyst	4	0.6	0.6	no signal
1023	Full Blood Count Decreased	8	0.6	0.6	no signal
1024	Injection Site Irritation	5	0.6	0.6	no signal
1025	Hip Arthroplasty	6	0.6	0.6	no signal
1026	Arthropathy	22	0.6	0.6	no signal
1027	Platelet Count Decreased	42	0.6	0.6	no signal
1028	Osteonecrosis	13	0.6	0.6	no signal
1029	Poor Venous Access	4	0.5	0.5	no signal
1030	Femur Fracture	12	0.5	0.5	no signal
1031	Injection Site Induration	5	0.5	0.5	no signal
1032	Liver Disorder	17	0.5	0.5	no signal
1033	Unintended Pregnancy	4	0.5	0.5	no signal
1034	Skeletal Injury	4	0.5	0.5	no signal
1035	Discomfort	23	0.5	0.5	no signal
1036	Mobility Decreased	27	0.5	0.5	no signal
1037	Pancytopenia	21	0.5	0.5	no signal
1038	Ascites	11	0.5	0.5	no signal
1039	Fluid Retention	19	0.5	0.5	no signal
1040	Nasopharyngitis	69	0.5	0.5	no signal
1041	Uveitis	5	0.5	0.5	no signal
1042	Hepatic Enzyme Increased	25	0.5	0.5	no signal
1043	Product Packaging Quantity Issue	4	0.5	0.5	no signal
1044	Musculoskeletal Disorder	7	0.5	0.5	no signal
1045	Impaired Healing	12	0.5	0.5	no signal
1046	Viral Infection	12	0.5	0.5	no signal
1047	Nephropathy Toxic	4	0.5	0.5	no signal
1048	Drug Ineffective For Unapproved Indication	20	0.5	0.5	no signal
1049	Eczema	18	0.5	0.5	no signal
1050	Glycosylated Haemoglobin Increased	9	0.5	0.5	no signal
1051	Dialysis	5	0.5	0.5	no signal
1052	Gastric Cancer	9	0.5	0.5	no signal
1053	Joint Swelling	42	0.5	0.5	no signal
1054	Neurotoxicity	6	0.5	0.5	no signal
1055	Product Prescribing Issue	7	0.5	0.5	no signal
1056	White Blood Cell Count Decreased	37	0.5	0.5	no signal
1057	Peritonitis	7	0.5	0.5	no signal
1058	Product Prescribing Error	8	0.5	0.5	no signal
1059	Haemorrhage Intracranial	5	0.5	0.5	no signal
1060	Multiple Sclerosis	16	0.5	0.5	no signal
1061	Drug Effect Decreased	18	0.5	0.5	no signal
1062	Blood Thyroid Stimulating Hormone Increased	3	0.5	0.5	no signal
1063	Psoriatic Arthropathy	13	0.5	0.5	no signal
1064	Lymphoma	5	0.5	0.5	no signal
1065	Metastases To Central Nervous System	4	0.4	0.4	no signal
1066	Accidental Exposure To Product	31	0.4	0.4	no signal
1067	Death	266	0.4	0.4	no signal
1068	Inability To Afford Medication	3	0.4	0.4	no signal
1069	Dry Skin	40	0.4	0.4	no signal
1070	Neoplasm Malignant	20	0.4	0.4	no signal
1071	Injection Site Mass	11	0.4	0.4	no signal
1072	Helicobacter Infection	3	0.4	0.4	no signal
1073	Gastrointestinal Disorder	26	0.4	0.4	no signal
1074	Poor Quality Product Administered	3	0.4	0.4	no signal
1075	Dysphonia	17	0.4	0.4	no signal
1076	Therapy Interrupted	20	0.4	0.4	no signal
1077	Menstruation Delayed	3	0.4	0.4	no signal
1078	Malignant Neoplasm Progression	29	0.4	0.4	no signal
1079	Therapeutic Response Shortened	9	0.4	0.4	no signal
1080	Plasma Cell Myeloma	11	0.4	0.4	no signal
1081	Disease Progression	33	0.4	0.4	no signal
1082	Needle Issue	8	0.4	0.4	no signal
1083	Pelvic Pain	5	0.4	0.4	no signal
1084	Eye Pruritus	9	0.4	0.4	no signal
1085	Blood Glucose Abnormal	5	0.4	0.4	no signal
1086	No Adverse Event	47	0.4	0.4	no signal
1087	Herpes Zoster	15	0.4	0.4	no signal
1088	Acute Myeloid Leukaemia	4	0.4	0.4	no signal
1089	Palmar-plantar Erythrodysaesthesia Syndrome	6	0.4	0.4	no signal
1090	Eye Pain	14	0.4	0.4	no signal
1091	Psoriasis	33	0.4	0.4	no signal
1092	Menorrhagia	5	0.4	0.4	no signal
1093	Covid-19	44	0.3	0.3	no signal
1094	Blindness	10	0.3	0.3	no signal
1095	Injection Site Discolouration	3	0.3	0.3	no signal
1096	Cataract	14	0.3	0.3	no signal
1097	Inflammation	12	0.3	0.3	no signal
1098	Intraocular Pressure Increased	3	0.3	0.3	no signal
1099	Genital Haemorrhage	3	0.3	0.3	no signal
1100	Disease Recurrence	11	0.3	0.3	no signal
1101	Dysmenorrhoea	3	0.3	0.3	no signal
1102	Alopecia	45	0.3	0.3	no signal
1103	Injection Site Pruritus	15	0.3	0.3	no signal
1104	Rheumatoid Arthritis	25	0.3	0.3	no signal
1105	Dermatitis Atopic	11	0.3	0.3	no signal
1106	Prostatic Specific Antigen Increased	3	0.3	0.3	no signal
1107	Hepatic Cancer	5	0.3	0.3	no signal
1108	Injection Site Rash	6	0.3	0.3	no signal
1109	Sickle Cell Anaemia With Crisis	3	0.3	0.3	no signal
1110	Treatment Failure	15	0.3	0.3	no signal
1111	Amenorrhoea	3	0.3	0.3	no signal
1112	Eye Irritation	10	0.3	0.3	no signal
1113	Exposure Via Skin Contact	4	0.2	0.2	no signal
1114	Injection Site Reaction	12	0.2	0.2	no signal
1115	Metrorrhagia	3	0.2	0.2	no signal
1116	Injection Site Pain	46	0.2	0.2	no signal
1117	Injury Associated With Device	3	0.2	0.2	no signal
1118	Circumstance Or Information Capable Of Leading To Medication Error	5	0.2	0.2	no signal
1119	Device Dislocation	6	0.2	0.2	no signal
1120	Device Malfunction	9	0.2	0.2	no signal
1121	Oesophageal Carcinoma	4	0.2	0.2	no signal
1122	Injection Site Swelling	10	0.2	0.2	no signal
1123	Wrong Technique In Device Usage Process	6	0.2	0.2	no signal
1124	Gynaecomastia	4	0.2	0.2	no signal
1125	Acne	9	0.2	0.2	no signal
1126	Device Issue	10	0.2	0.2	no signal
1127	Injection Site Erythema	14	0.2	0.2	no signal
1128	Menstruation Irregular	3	0.2	0.2	no signal
1129	Breast Cancer Female	3	0.2	0.2	no signal
1130	Bladder Cancer	5	0.1	0.1	no signal
1131	Renal Cancer	4	0.1	0.1	no signal
1132	Device Difficult To Use	4	0.1	0.1	no signal
1133	Device Expulsion	3	0.1	0.1	no signal