OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Nicotine Polarilex

1,133 flagged reaction(s) · 62,960 total co-reports · max PRR 1,962.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Vaginal Flatulence 177 1,962.7 1,986.3 signal
2 Rhesus Incompatibility 68 1,778.4 1,786.5 signal
3 Plethysmography 14 1,617.1 1,618.6 signal
4 Truncus Arteriosus Persistent 74 820.6 824.7 signal
5 Tobacco Poisoning 30 533.1 534.2 signal
6 Myocardial Stunning 24 305.2 305.7 signal
7 Tobacco Interaction 16 233.4 233.7 signal
8 Lung Diffusion Disorder 18 180.8 181.0 signal
9 Female Genital Tract Fistula 181 165.3 167.3 signal
10 Tobacco Abuse 50 143.2 143.7 signal
11 Nicotine Dependence 715 140.6 147.6 signal
12 Cardiac Septal Defect 54 113.2 113.6 signal
13 Tremor Neonatal 32 107.7 107.9 signal
14 Diarrhoea Neonatal 9 105.7 105.8 signal
15 Multiple Drug Overdose Accidental 32 104.1 104.3 signal
16 Radiculopathy 180 103.0 104.2 signal
17 Congenital Cardiovascular Anomaly 57 101.0 101.4 signal
18 Weight Decrease Neonatal 13 100.1 100.2 signal
19 Neutropenia Neonatal 15 100.0 100.1 signal
20 Proctitis 183 98.1 99.3 signal
21 Poor Feeding Infant 69 97.0 97.4 signal
22 Chronic Sinusitis 239 95.8 97.3 signal
23 Idiopathic Interstitial Pneumonia 18 77.5 77.6 signal
24 Congenital Tricuspid Valve Incompetence 10 77.0 77.1 signal
25 Jaundice Neonatal 96 74.9 75.4 signal
26 Mediastinal Mass 18 70.3 70.4 signal
27 Macular Degeneration 563 69.7 72.4 signal
28 Adenoidectomy 18 68.9 69.0 signal
29 Congenital Pulmonary Hypertension 9 67.8 67.8 signal
30 Necrosis Ischaemic 20 63.4 63.5 signal
31 Pulmonary Eosinophilia 19 60.3 60.3 signal
32 Neonatal Aspiration 13 57.2 57.3 signal
33 Breech Presentation 49 56.9 57.1 signal
34 Postmortem Blood Drug Level Increased 14 56.4 56.5 signal
35 Respiratory Gas Exchange Disorder 14 55.1 55.2 signal
36 Substance Dependence 25 54.5 54.6 signal
37 Sputum Purulent 24 52.8 52.9 signal
38 Tooth Erosion 40 51.1 51.2 signal
39 Exposure During Breast Feeding 114 49.3 49.7 signal
40 Loss Of Proprioception 11 49.2 49.2 signal
41 Exposure Via Breast Milk 126 46.7 47.1 signal
42 Foetal Disorder 27 46.4 46.5 signal
43 Bronchial Wall Thickening 19 37.8 37.8 signal
44 Hyperbilirubinaemia Neonatal 15 37.2 37.2 signal
45 Foetal Distress Syndrome 54 36.7 36.8 signal
46 Drug Withdrawal Syndrome Neonatal 375 36.1 37.0 signal
47 Gastroschisis 12 35.9 36.0 signal
48 Diaphragmatic Disorder 19 35.5 35.5 signal
49 Low Birth Weight Baby 175 31.6 32.0 signal
50 Agitation Neonatal 20 30.1 30.1 signal
51 Product Adhesion Issue 727 29.4 30.9 signal
52 Secondary Immunodeficiency 24 28.8 28.8 signal
53 Pneumonia Streptococcal 22 28.7 28.8 signal
54 Tobacco User 30 28.7 28.8 signal
55 Substance Abuse 157 27.6 27.9 signal
56 Drug Detoxification 17 27.3 27.3 signal
57 Alcohol Abuse 51 27.1 27.2 signal
58 Pulmonary Granuloma 21 26.1 26.1 signal
59 Vaginal Discharge 182 25.9 26.2 signal
60 Cleft Lip 15 24.2 24.3 signal
61 Umbilical Cord Around Neck 10 24.0 24.0 signal
62 Beta Haemolytic Streptococcal Infection 21 23.9 23.9 signal
63 Alcohol Withdrawal Syndrome 14 22.8 22.8 signal
64 Multiple Drug Overdose 80 22.7 22.8 signal
65 Paraesthesia Oral 228 22.6 23.0 signal
66 Premature Delivery 251 22.4 22.8 signal
67 Infective Exacerbation Of Chronic Obstructive Airways Disease 10 22.2 22.2 signal
68 Borderline Personality Disorder 11 22.1 22.1 signal
69 Ventricular Septal Defect 89 22.0 22.2 signal
70 Pressure Of Speech 10 21.9 21.9 signal
71 Placenta Praevia 12 21.6 21.6 signal
72 Heart Disease Congenital 54 21.6 21.6 signal
73 Bronchial Secretion Retention 19 21.4 21.5 signal
74 Neonatal Respiratory Distress 13 21.4 21.4 signal
75 Oral Candidiasis 192 21.0 21.3 signal
76 Microcephaly 18 20.2 20.2 signal
77 Feeding Disorder Neonatal 15 20.1 20.2 signal
78 Accidental Death 26 20.0 20.0 signal
79 Ophthalmoplegia 22 19.9 20.0 signal
80 Axonal Neuropathy 12 19.8 19.9 signal
81 Cardiac Death 17 19.8 19.8 signal
82 Application Site Scar 17 19.3 19.3 signal
83 Counterfeit Product Administered 17 19.0 19.0 signal
84 Reversible Cerebral Vasoconstriction Syndrome 26 18.9 18.9 signal
85 Cytokine Storm 9 18.8 18.8 signal
86 Antisocial Behaviour 13 18.3 18.4 signal
87 Alcohol Interaction 25 18.2 18.3 signal
88 Treatment Noncompliance 664 17.4 18.1 signal
89 Myocardial Fibrosis 10 16.9 16.9 signal
90 Bronchial Hyperreactivity 14 16.5 16.5 signal
91 Jaw Fracture 25 16.4 16.4 signal
92 Tonsillectomy 19 16.1 16.2 signal
93 Neonatal Disorder 18 16.0 16.1 signal
94 Mycobacterial Infection 19 15.7 15.7 signal
95 Neuropsychiatric Symptoms 10 15.5 15.5 signal
96 Premature Baby 323 15.2 15.5 signal
97 Respiratory Disorder Neonatal 17 15.2 15.2 signal
98 Application Site Dermatitis 10 15.1 15.1 signal
99 Nasal Oedema 19 15.0 15.1 signal
100 Non-alcoholic Steatohepatitis 11 14.9 14.9 signal
101 Premature Separation Of Placenta 16 14.6 14.7 signal
102 Rhonchi 14 14.3 14.3 signal
103 Prinzmetal Angina 10 14.3 14.3 signal
104 Schizoaffective Disorder 18 14.2 14.3 signal
105 Disinhibition 16 14.1 14.1 signal
106 Cleft Palate 19 13.9 13.9 signal
107 Cleft Lip And Palate 11 13.8 13.8 signal
108 Methaemoglobinaemia 22 13.6 13.6 signal
109 Oligohydramnios 32 13.5 13.6 signal
110 Bone Demineralisation 10 13.4 13.4 signal
111 Chronic Kidney Disease-mineral And Bone Disorder 10 13.2 13.2 signal
112 Antipsychotic Drug Level Increased 26 13.1 13.1 signal
113 Foetal Exposure During Pregnancy 744 13.0 13.6 signal
114 Gastric Dilatation 15 12.8 12.8 signal
115 Intentional Drug Misuse 190 12.7 12.8 signal
116 Application Site Urticaria 20 12.5 12.5 signal
117 Body Temperature Abnormal 16 12.3 12.3 signal
118 Gestational Hypertension 11 12.2 12.2 signal
119 Application Site Warmth 11 12.2 12.2 signal
120 Application Site Pruritus 193 12.0 12.2 signal
121 Gambling Disorder 23 12.0 12.0 signal
122 Exposure Via Father 11 11.8 11.8 signal
123 Claustrophobia 9 11.7 11.7 signal
124 Clostridium Test Positive 18 11.7 11.7 signal
125 Compulsive Shopping 17 11.6 11.6 signal
126 Application Site Erythema 216 11.6 11.8 signal
127 Nephrogenic Anaemia 38 11.5 11.5 signal
128 Application Site Rash 111 11.4 11.5 signal
129 Blood Immunoglobulin E Increased 19 11.0 11.1 signal
130 Drug Effect Increased 25 11.0 11.0 signal
131 Substance Use 12 11.0 11.0 signal
132 Mean Cell Volume Decreased 12 11.0 11.0 signal
133 Incorrect Drug Administration Duration 221 11.0 11.1 signal
134 Application Site Vesicles 50 10.9 10.9 signal
135 Product Monitoring Error 11 10.9 10.9 signal
136 Gun Shot Wound 14 10.4 10.4 signal
137 Procedural Pain 203 10.4 10.5 signal
138 Drug Screen Positive 57 10.2 10.3 signal
139 Frequent Bowel Movements 194 10.2 10.3 signal
140 Abnormal Dreams 200 10.2 10.3 signal
141 Alcohol Poisoning 19 10.1 10.1 signal
142 Mean Cell Haemoglobin Decreased 13 10.0 10.0 signal
143 Regurgitation 24 9.9 9.9 signal
144 Emphysema 71 9.9 10.0 signal
145 Abortion Induced 65 9.8 9.8 signal
146 Rebound Acid Hypersecretion 21 9.7 9.7 signal
147 Left Ventricular Hypertrophy 29 9.6 9.6 signal
148 Application Site Burn 33 9.4 9.4 signal
149 Caesarean Section 78 9.4 9.4 signal
150 Mean Cell Haemoglobin Concentration Decreased 11 9.3 9.4 signal
151 Dental Caries 73 9.3 9.4 signal
152 Lobar Pneumonia 12 9.0 9.0 signal
153 Drug Toxicity 88 9.0 9.1 signal
154 Hyperparathyroidism Secondary 16 8.9 8.9 signal
155 Vitamin B12 Deficiency 25 8.8 8.8 signal
156 Bronchiolitis 22 8.8 8.8 signal
157 Premature Labour 35 8.7 8.7 signal
158 Maternal Drugs Affecting Foetus 47 8.6 8.6 signal
159 Oedema Mouth 20 8.6 8.6 signal
160 Application Site Swelling 30 8.5 8.5 signal
161 Drug Abuser 37 8.4 8.4 signal
162 Drug Use Disorder 49 8.4 8.4 signal
163 Retroperitoneal Haematoma 13 8.4 8.4 signal
164 Pre-eclampsia 28 8.3 8.4 signal
165 Hypertensive Heart Disease 11 8.3 8.3 signal
166 Obstructive Airways Disorder 64 8.1 8.1 signal
167 Bronchitis Chronic 14 8.0 8.1 signal
168 Colitis 214 8.0 8.1 signal
169 Patent Ductus Arteriosus 22 7.8 7.8 signal
170 Euphoric Mood 56 7.7 7.7 signal
171 Aortic Arteriosclerosis 14 7.7 7.7 signal
172 Small For Dates Baby 27 7.6 7.7 signal
173 Homicidal Ideation 22 7.6 7.6 signal
174 Stenosis 10 7.6 7.6 signal
175 Atelectasis 52 7.6 7.6 signal
176 Neonatal Respiratory Distress Syndrome 19 7.6 7.6 signal
177 Rectal Haemorrhage 228 7.5 7.6 signal
178 Application Site Irritation 65 7.4 7.4 signal
179 Bile Duct Obstruction 10 7.3 7.3 signal
180 Priapism 18 7.3 7.3 signal
181 Arteriosclerosis Coronary Artery 34 7.3 7.3 signal
182 Maternal Exposure During Pregnancy 447 7.2 7.3 signal
183 Electrocardiogram St Segment Depression 11 7.0 7.0 signal
184 Intentional Underdose 36 7.0 7.0 signal
185 Application Site Reaction 35 7.0 7.0 signal
186 Full Blood Count Abnormal 52 7.0 7.0 signal
187 Functional Gastrointestinal Disorder 17 6.9 6.9 signal
188 Maternal Exposure During Breast Feeding 19 6.8 6.8 signal
189 Umbilical Hernia 22 6.6 6.6 signal
190 Economic Problem 72 6.6 6.6 signal
191 Application Site Discolouration 19 6.6 6.6 signal
192 Transfusion 49 6.6 6.6 signal
193 Foetal Growth Restriction 28 6.5 6.6 signal
194 Colitis Ulcerative 204 6.5 6.5 signal
195 Drug Abuse 381 6.4 6.6 signal
196 Product Complaint 112 6.3 6.4 signal
197 Vasodilatation 11 6.2 6.2 signal
198 Red Cell Distribution Width Increased 18 6.1 6.1 signal
199 Alcohol Use 16 6.1 6.1 signal
200 Potentiating Drug Interaction 14 6.0 6.0 signal
201 Snoring 16 6.0 6.0 signal
202 Substance Use Disorder 13 6.0 6.0 signal
203 Bipolar Disorder 46 5.9 5.9 signal
204 Sinus Tachycardia 59 5.9 5.9 signal
205 Nasal Polyps 20 5.8 5.9 signal
206 Therapeutic Product Effect Incomplete 293 5.8 5.9 signal
207 Drug Tolerance 21 5.8 5.8 signal
208 Application Site Pain 91 5.8 5.9 signal
209 Nightmare 143 5.8 5.8 signal
210 Self-injurious Ideation 17 5.7 5.7 signal
211 Ventricular Hypokinesia 13 5.7 5.7 signal
212 Chronic Obstructive Pulmonary Disease 209 5.7 5.7 signal
213 Metabolic Encephalopathy 12 5.6 5.6 signal
214 Alcoholism 17 5.6 5.6 signal
215 Incorrect Product Administration Duration 79 5.5 5.5 signal
216 Post-traumatic Stress Disorder 26 5.5 5.5 signal
217 Lip Pain 11 5.4 5.4 signal
218 Musculoskeletal Chest Pain 59 5.4 5.4 signal
219 Anhedonia 100 5.3 5.4 signal
220 Non-cardiac Chest Pain 12 5.3 5.3 signal
221 Haematochezia 207 5.3 5.4 signal
222 Obsessive-compulsive Disorder 30 5.2 5.2 signal
223 Electrocardiogram Qrs Complex Prolonged 19 5.2 5.2 signal
224 Sputum Discoloured 35 5.2 5.2 signal
225 Accidental Overdose 134 5.2 5.2 signal
226 Arteriosclerosis 34 5.1 5.1 signal
227 Rash Morbilliform 10 5.1 5.1 signal
228 End Stage Renal Disease 66 5.1 5.1 signal
229 Toxicity To Various Agents 596 5.0 5.2 signal
230 Major Depression 26 5.0 5.0 signal
231 Product Administration Interrupted 27 5.0 5.0 signal
232 Gingivitis 19 5.0 5.0 signal
233 Overdose 762 5.0 5.2 signal
234 Miosis 28 5.0 5.0 signal
235 Eosinophil Count Increased 29 4.9 4.9 signal
236 Lung Cancer Metastatic 10 4.9 4.9 signal
237 Pulmonary Congestion 46 4.9 4.9 signal
238 Infusion Related Reaction 228 4.9 4.9 signal
239 Left Ventricular Dysfunction 23 4.9 4.9 signal
240 Schizophrenia 41 4.8 4.8 signal
241 Brain Oedema 42 4.7 4.7 signal
242 Partial Seizures 17 4.6 4.6 signal
243 Throat Cancer 14 4.6 4.6 signal
244 Wrong Technique In Drug Usage Process 121 4.6 4.7 signal
245 Mastication Disorder 10 4.6 4.6 signal
246 Tearfulness 14 4.6 4.6 signal
247 Ischaemic Cardiomyopathy 10 4.5 4.6 signal
248 Hallucination, Auditory 51 4.5 4.5 signal
249 Troponin Increased 24 4.5 4.5 signal
250 Depression Suicidal 11 4.5 4.5 signal
251 Self-medication 13 4.5 4.5 signal
252 Pulmonary Oedema 141 4.4 4.5 signal
253 Stillbirth 15 4.3 4.4 signal
254 Dermatitis Contact 35 4.3 4.4 signal
255 Cardiopulmonary Failure 12 4.3 4.3 signal
256 Dyspepsia 297 4.3 4.3 signal
257 Myoclonus 36 4.3 4.3 signal
258 Peptic Ulcer 10 4.2 4.2 signal
259 Cardiomegaly 37 4.2 4.2 signal
260 Drug Diversion 17 4.2 4.2 signal
261 Atrioventricular Block Second Degree 9 4.2 4.2 signal
262 Product Quality Issue 398 4.2 4.2 signal
263 Spinal Osteoarthritis 26 4.1 4.2 signal
264 Hiccups 24 4.1 4.1 signal
265 Affective Disorder 23 4.1 4.1 signal
266 Enterococcal Infection 14 4.1 4.1 signal
267 Gingival Pain 23 4.1 4.1 signal
268 Tachyphrenia 10 4.1 4.1 signal
269 Toothache 52 4.0 4.1 signal
270 Necrotising Fasciitis 10 4.0 4.0 signal
271 Pulmonary Mass 42 4.0 4.0 signal
272 Multiple Injuries 18 4.0 4.0 signal
273 Drug Dependence 459 4.0 4.1 signal
274 Chronic Kidney Disease 216 4.0 4.0 signal
275 Oropharyngeal Discomfort 25 3.9 3.9 signal
276 Product Dose Omission 185 3.9 4.0 signal
277 Expired Drug Administered 14 3.9 3.9 signal
278 Inguinal Hernia 17 3.9 3.9 signal
279 Monocyte Count Increased 10 3.9 3.9 signal
280 Renal Tubular Necrosis 27 3.9 3.9 signal
281 Feeling Jittery 52 3.8 3.8 signal
282 Exposure During Pregnancy 169 3.8 3.9 signal
283 Hypomania 10 3.8 3.8 signal
284 Serotonin Syndrome 51 3.8 3.8 signal
285 Mental Status Changes 74 3.7 3.8 signal
286 Underdose 194 3.7 3.8 signal
287 Myocarditis 30 3.7 3.7 signal
288 Withdrawal Syndrome 110 3.7 3.7 signal
289 Unresponsive To Stimuli 67 3.7 3.7 signal
290 Wheezing 154 3.7 3.7 signal
291 Salivary Hypersecretion 26 3.7 3.7 signal
292 Abscess Limb 11 3.6 3.6 signal
293 Mitral Valve Incompetence 29 3.6 3.6 signal
294 Lung Neoplasm 11 3.6 3.6 signal
295 Malnutrition 28 3.5 3.6 signal
296 Iron Deficiency 11 3.5 3.5 signal
297 Exercise Tolerance Decreased 14 3.5 3.5 signal
298 Peripheral Ischaemia 10 3.4 3.4 signal
299 Concomitant Disease Aggravated 15 3.4 3.4 signal
300 Hypoxia 84 3.4 3.4 signal
301 Pre-existing Condition Improved 15 3.3 3.3 signal
302 Irritability 143 3.3 3.4 signal
303 Deafness Unilateral 13 3.3 3.3 signal
304 Osteopenia 36 3.3 3.3 signal
305 Panic Reaction 17 3.3 3.3 signal
306 Psychomotor Hyperactivity 39 3.3 3.3 signal
307 Gestational Diabetes 11 3.3 3.3 signal
308 Loss Of Libido 21 3.3 3.3 signal
309 Hyperlipidaemia 28 3.3 3.3 signal
310 Anger 79 3.3 3.3 signal
311 Ischaemic Stroke 41 3.2 3.2 signal
312 Electrocardiogram Abnormal 18 3.2 3.2 signal
313 Tricuspid Valve Incompetence 18 3.2 3.2 signal
314 Drug Interaction 360 3.2 3.2 signal
315 Oliguria 14 3.2 3.2 signal
316 Thermal Burn 16 3.2 3.2 signal
317 Paranoia 39 3.2 3.2 signal
318 Social Avoidant Behaviour 13 3.2 3.2 signal
319 Haemoglobin Increased 10 3.1 3.1 signal
320 Shock Haemorrhagic 18 3.1 3.1 signal
321 Candidiasis 9 3.1 3.1 signal
322 Sedation 57 3.1 3.1 signal
323 Cardiac Murmur 19 3.1 3.1 signal
324 Restlessness 80 3.1 3.1 signal
325 Coronary Artery Stenosis 11 3.1 3.1 signal
326 Drug Level Increased 36 3.1 3.1 signal
327 Delirium 75 3.1 3.1 signal
328 Drug Withdrawal Syndrome 190 3.0 3.0 signal
329 Neutrophil Count Increased 22 3.0 3.0 signal
330 Tension 13 3.0 3.0 signal
331 Respiratory Arrest 59 3.0 3.0 signal
332 Panic Attack 77 3.0 3.0 signal
333 Pulse Absent 10 2.9 3.0 signal
334 Oral Discomfort 29 2.9 2.9 signal
335 Expired Product Administered 69 2.9 2.9 signal
336 Nystagmus 11 2.9 2.9 signal
337 Obesity 33 2.9 2.9 signal
338 Psychotic Disorder 61 2.9 2.9 signal
339 Nerve Injury 23 2.9 2.9 signal
340 Tooth Abscess 21 2.9 2.9 signal
341 Suicidal Ideation 188 2.9 2.9 signal
342 Sleep Apnoea Syndrome 39 2.9 2.9 signal
343 Energy Increased 12 2.8 2.8 signal
344 Depressed Mood 106 2.8 2.8 signal
345 Intentional Product Misuse 174 2.8 2.8 signal
346 Tooth Fracture 22 2.8 2.8 signal
347 Platelet Count Increased 26 2.8 2.8 signal
348 Hepatic Steatosis 37 2.8 2.8 signal
349 Respiratory Failure 145 2.8 2.8 signal
350 Acute Respiratory Failure 38 2.8 2.8 signal
351 Increased Appetite 37 2.8 2.8 signal
352 Necrosis 11 2.8 2.8 signal
353 Endocarditis 10 2.7 2.8 signal
354 Bundle Branch Block Right 9 2.7 2.7 signal
355 Mood Swings 62 2.7 2.7 signal
356 Ataxia 23 2.7 2.7 signal
357 Dependence 107 2.7 2.7 signal
358 Cerebral Ischaemia 10 2.7 2.7 signal
359 Productive Cough 91 2.7 2.7 signal
360 Respiratory Distress 53 2.7 2.7 signal
361 Completed Suicide 161 2.7 2.7 signal
362 Constipation 411 2.7 2.7 signal
363 Vasculitis 22 2.7 2.7 signal
364 Nervousness 99 2.7 2.7 signal
365 Tachycardia 167 2.6 2.7 signal
366 Loss Of Consciousness 241 2.6 2.7 signal
367 Tubulointerstitial Nephritis 35 2.6 2.6 signal
368 Tooth Loss 39 2.6 2.6 signal
369 Electrocardiogram Qt Prolonged 67 2.6 2.6 signal
370 Apathy 27 2.6 2.6 signal
371 Refusal Of Treatment By Patient 12 2.6 2.6 signal
372 Type 1 Diabetes Mellitus 11 2.6 2.6 signal
373 Myocardial Ischaemia 21 2.6 2.6 signal
374 Somnambulism 12 2.6 2.6 signal
375 Agitation 134 2.6 2.6 signal
376 Prothrombin Time Prolonged 11 2.6 2.6 signal
377 Neutropenic Sepsis 13 2.6 2.6 signal
378 Dyspnoea Exertional 68 2.5 2.6 signal
379 Anxiety 516 2.5 2.6 signal
380 Dysarthria 68 2.5 2.6 signal
381 Pharyngeal Oedema 28 2.5 2.5 signal
382 Sneezing 40 2.5 2.5 signal
383 Torsade De Pointes 14 2.5 2.5 signal
384 Cyanosis 28 2.5 2.5 signal
385 Arterial Occlusive Disease 14 2.5 2.5 signal
386 Blood Sodium Decreased 33 2.5 2.5 signal
387 Drooling 12 2.5 2.5 signal
388 Poisoning 22 2.5 2.5 signal
389 Oral Pain 39 2.4 2.4 signal
390 Drug Administration Error 54 2.4 2.4 signal
391 Acute Kidney Injury 264 2.4 2.5 signal
392 Palpitations 202 2.4 2.4 signal
393 Upper Gastrointestinal Haemorrhage 29 2.4 2.4 signal
394 Mania 28 2.4 2.4 signal
395 Hiatus Hernia 22 2.4 2.4 signal
396 Clostridium Difficile Colitis 18 2.4 2.4 signal
397 Brain Injury 17 2.4 2.4 signal
398 Anal Incontinence 15 2.4 2.4 signal
399 Inappropriate Antidiuretic Hormone Secretion 17 2.3 2.4 signal
400 Diverticulum 12 2.3 2.3 signal
401 Renal Injury 50 2.3 2.3 signal
402 Aspiration 18 2.3 2.3 signal
403 Skin Plaque 14 2.3 2.3 signal
404 Rib Fracture 34 2.3 2.3 signal
405 Mental Disorder 72 2.3 2.3 signal
406 Electrolyte Imbalance 19 2.3 2.3 signal
407 Hallucination 123 2.3 2.3 signal
408 Abortion Spontaneous 66 2.3 2.3 signal
409 Coma 78 2.3 2.3 signal
410 Renal Cyst 13 2.3 2.3 signal
411 Eructation 31 2.3 2.3 signal
412 Ventricular Tachycardia 27 2.3 2.3 signal
413 Infusion Site Swelling 10 2.3 2.3 signal
414 Convulsion 94 2.3 2.3 signal
415 Aggression 81 2.3 2.3 signal
416 Oxygen Saturation Decreased 90 2.3 2.3 signal
417 Intervertebral Disc Degeneration 15 2.3 2.3 signal
418 Sensory Loss 13 2.3 2.3 signal
419 Gingival Bleeding 22 2.3 2.3 signal
420 Pneumonia Aspiration 40 2.3 2.3 signal
421 Leukocytosis 29 2.3 2.3 signal
422 Cold Sweat 28 2.2 2.2 signal
423 Abnormal Faeces 13 2.2 2.2 signal
424 Hyperhidrosis 204 2.2 2.2 signal
425 Anaemia 300 2.2 2.2 signal
426 Abdominal Pain 365 2.2 2.2 signal
427 Hypercholesterolaemia 15 2.2 2.2 signal
428 Live Birth 13 2.2 2.2 signal
429 Acute Coronary Syndrome 13 2.2 2.2 signal
430 Disseminated Intravascular Coagulation 22 2.2 2.2 signal
431 Sleep Disorder 109 2.2 2.2 signal
432 Cardiomyopathy 23 2.2 2.2 signal
433 Erythema 318 2.2 2.2 signal
434 Atrial Septal Defect 13 2.2 2.2 signal
435 Coronary Artery Occlusion 21 2.1 2.1 signal
436 Hyperkalaemia 53 2.1 2.1 signal
437 Blood Albumin Decreased 12 2.1 2.1 signal
438 Incontinence 16 2.1 2.1 signal
439 Muscle Strain 13 2.1 2.1 signal
440 Blood Creatine Phosphokinase Increased 44 2.1 2.1 signal
441 Hypokalaemia 69 2.1 2.1 signal
442 Prescribed Overdose 29 2.1 2.1 signal
443 Cardiac Arrest 124 2.1 2.1 signal
444 Skin Reaction 21 2.1 2.1 signal
445 Rash Maculo-papular 33 2.1 2.1 signal
446 Renal Failure 199 2.1 2.1 signal
447 Lower Gastrointestinal Haemorrhage 11 2.1 2.1 signal
448 Ejection Fraction Decreased 23 2.1 2.1 signal
449 Hepatitis C 18 2.1 2.1 signal
450 Decubitus Ulcer 12 2.1 2.1 signal
451 Maternal Exposure Before Pregnancy 10 2.1 2.1 signal
452 Lymphocyte Count Decreased 26 2.1 2.1 signal
453 Encephalopathy 36 2.1 2.1 signal
454 Depression 335 2.1 2.1 signal
455 Accidental Exposure To Product By Child 10 2.1 2.1 signal
456 Septic Shock 63 2.1 2.1 signal
457 Angina Pectoris 42 2.0 2.1 signal
458 Libido Decreased 18 2.0 2.0 signal
459 Acute Myocardial Infarction 43 2.0 2.0 signal
460 Drug Exposure During Pregnancy 50 2.0 2.0 signal
461 Poor Quality Sleep 31 2.0 2.0 signal
462 Cellulitis 73 2.0 2.0 signal
463 Bacteraemia 17 2.0 2.0 signal
464 Product Use Issue 270 2.0 2.1 signal
465 Mental Impairment 35 2.0 2.0 signal
466 Papule 10 2.0 2.0 signal
467 Vitamin D Deficiency 14 2.0 2.0 signal
468 Formication 10 2.0 2.0 signal
469 Osteoporosis 59 2.0 2.0 signal
470 Injury 101 2.0 2.0 signal
471 Product Availability Issue 32 2.0 2.0 signal
472 Depressed Level Of Consciousness 56 2.0 2.0 no signal
473 Chest Pain 263 2.0 2.0 no signal
474 Pruritus Generalised 31 2.0 2.0 no signal
475 Blood Triglycerides Increased 25 2.0 2.0 no signal
476 Urosepsis 13 2.0 2.0 no signal
477 Hyperglycaemia 51 2.0 2.0 no signal
478 Cardio-respiratory Arrest 59 2.0 2.0 no signal
479 Product Preparation Error 29 2.0 2.0 no signal
480 Intentional Overdose 89 2.0 2.0 no signal
481 Insomnia 371 2.0 2.0 no signal
482 Personality Change 13 2.0 2.0 no signal
483 Blood Magnesium Decreased 12 2.0 2.0 no signal
484 Hallucination, Visual 29 1.9 1.9 no signal
485 Wrong Technique In Product Usage Process 279 1.9 2.0 no signal
486 Drug Dose Omission 231 1.9 2.0 no signal
487 Tremor 229 1.9 2.0 no signal
488 Product Administered At Inappropriate Site 25 1.9 1.9 no signal
489 Pain In Jaw 39 1.9 1.9 no signal
490 Fear 37 1.9 1.9 no signal
491 Mouth Haemorrhage 10 1.9 1.9 no signal
492 Sleep Disorder Due To A General Medical Condition 22 1.9 1.9 no signal
493 Gastrooesophageal Reflux Disease 109 1.9 1.9 no signal
494 Face Oedema 23 1.9 1.9 no signal
495 Haematocrit Decreased 27 1.9 1.9 no signal
496 Dry Mouth 109 1.9 1.9 no signal
497 Asphyxia 11 1.9 1.9 no signal
498 Neuroleptic Malignant Syndrome 16 1.9 1.9 no signal
499 Muscle Rigidity 16 1.9 1.9 no signal
500 Pregnancy 27 1.9 1.9 no signal
501 Sinus Congestion 18 1.9 1.9 no signal
502 Hyperaesthesia 11 1.9 1.9 no signal
503 Confusional State 215 1.9 1.9 no signal
504 Mydriasis 17 1.9 1.9 no signal
505 Haemoptysis 37 1.9 1.9 no signal
506 Heart Rate Increased 131 1.9 1.9 no signal
507 Emotional Disorder 41 1.9 1.9 no signal
508 Malaise 579 1.9 1.9 no signal
509 Weight Decreased 367 1.8 1.9 no signal
510 Spinal Compression Fracture 11 1.8 1.8 no signal
511 Body Temperature Decreased 13 1.8 1.8 no signal
512 Abdominal Distension 136 1.8 1.8 no signal
513 Stress 94 1.8 1.8 no signal
514 Respiratory Depression 16 1.8 1.8 no signal
515 Small Intestinal Obstruction 16 1.8 1.8 no signal
516 Nausea 1,020 1.8 1.9 no signal
517 Poisoning Deliberate 12 1.8 1.8 no signal
518 Tooth Infection 17 1.8 1.8 no signal
519 Crying 47 1.8 1.8 no signal
520 Pallor 35 1.8 1.8 no signal
521 Scar 22 1.8 1.8 no signal
522 Hypothermia 13 1.8 1.8 no signal
523 Thinking Abnormal 24 1.8 1.8 no signal
524 Grand Mal Convulsion 12 1.8 1.8 no signal
525 Abnormal Behaviour 51 1.8 1.8 no signal
526 Photosensitivity Reaction 21 1.8 1.8 no signal
527 Heart Rate Irregular 29 1.8 1.8 no signal
528 Asthma 143 1.8 1.8 no signal
529 C-reactive Protein Increased 46 1.8 1.8 no signal
530 Spinal Disorder 12 1.8 1.8 no signal
531 Oropharyngeal Pain 117 1.8 1.8 no signal
532 Eating Disorder 27 1.8 1.8 no signal
533 Pneumothorax 20 1.8 1.8 no signal
534 Cardiogenic Shock 18 1.8 1.8 no signal
535 Disorientation 50 1.8 1.8 no signal
536 Disturbance In Attention 68 1.8 1.8 no signal
537 Febrile Neutropenia 83 1.8 1.8 no signal
538 Ventricular Extrasystoles 13 1.8 1.8 no signal
539 Coronary Artery Disease 38 1.8 1.8 no signal
540 Nocturia 15 1.7 1.7 no signal
541 Respiratory Rate Increased 11 1.7 1.7 no signal
542 Lung Infiltration 11 1.7 1.7 no signal
543 Scab 14 1.7 1.7 no signal
544 Circulatory Collapse 21 1.7 1.7 no signal
545 Bronchitis 91 1.7 1.7 no signal
546 Musculoskeletal Discomfort 21 1.7 1.7 no signal
547 Upper-airway Cough Syndrome 10 1.7 1.7 no signal
548 Polyuria 10 1.7 1.7 no signal
549 Anaphylactic Reaction 67 1.7 1.7 no signal
550 Osteomyelitis 22 1.7 1.7 no signal
551 Decreased Activity 13 1.7 1.7 no signal
552 Skin Lesion 33 1.7 1.7 no signal
553 Cardiovascular Disorder 31 1.7 1.7 no signal
554 Pancreatitis Acute 27 1.7 1.7 no signal
555 Foot Fracture 23 1.7 1.7 no signal
556 Developmental Delay 11 1.7 1.7 no signal
557 Renal Failure Acute 52 1.7 1.7 no signal
558 Orthostatic Hypotension 21 1.7 1.7 no signal
559 Metabolic Acidosis 38 1.7 1.7 no signal
560 Hypotension 240 1.7 1.7 no signal
561 Brain Neoplasm 11 1.7 1.7 no signal
562 Hypotonia 12 1.7 1.7 no signal
563 Fibromyalgia 29 1.7 1.7 no signal
564 Intentional Self-injury 24 1.7 1.7 no signal
565 Hypersomnia 34 1.7 1.7 no signal
566 Toxic Skin Eruption 12 1.7 1.7 no signal
567 Lethargy 68 1.7 1.7 no signal
568 Pleural Effusion 72 1.7 1.7 no signal
569 Pyrexia 408 1.7 1.7 no signal
570 Akathisia 16 1.6 1.6 no signal
571 Head Injury 37 1.6 1.6 no signal
572 Blood Count Abnormal 18 1.6 1.6 no signal
573 Road Traffic Accident 49 1.6 1.6 no signal
574 Hyperbilirubinaemia 12 1.6 1.6 no signal
575 Tooth Disorder 26 1.6 1.6 no signal
576 Atrioventricular Block 9 1.6 1.6 no signal
577 Scratch 12 1.6 1.6 no signal
578 Anuria 10 1.6 1.6 no signal
579 Drug Ineffective 1,517 1.6 1.7 no signal
580 Suicide Attempt 70 1.6 1.6 no signal
581 Impaired Driving Ability 13 1.6 1.6 no signal
582 Gastritis 30 1.6 1.6 no signal
583 Haematemesis 29 1.6 1.6 no signal
584 Intervertebral Disc Protrusion 25 1.6 1.6 no signal
585 Hyponatraemia 64 1.6 1.6 no signal
586 Emotional Distress 138 1.6 1.6 no signal
587 Respiratory Disorder 34 1.6 1.6 no signal
588 Blood Pressure Decreased 75 1.6 1.6 no signal
589 Retching 24 1.6 1.6 no signal
590 Neck Pain 63 1.6 1.6 no signal
591 Muscle Twitching 26 1.6 1.6 no signal
592 Blister 63 1.6 1.6 no signal
593 Diabetes Mellitus 86 1.6 1.6 no signal
594 Headache 702 1.6 1.6 no signal
595 Swollen Tongue 35 1.6 1.6 no signal
596 Feeling Abnormal 269 1.6 1.6 no signal
597 Quality Of Life Decreased 15 1.6 1.6 no signal
598 Hepatomegaly 11 1.6 1.6 no signal
599 Muscle Atrophy 14 1.6 1.6 no signal
600 Blood Potassium Increased 18 1.6 1.6 no signal
601 Syncope 111 1.6 1.6 no signal
602 Tachypnoea 15 1.6 1.6 no signal
603 Faeces Discoloured 24 1.6 1.6 no signal
604 Dizziness 550 1.6 1.6 no signal
605 Cytokine Release Syndrome 21 1.5 1.6 no signal
606 Blood Creatinine Increased 72 1.5 1.6 no signal
607 Chest Discomfort 112 1.5 1.5 no signal
608 Shock 25 1.5 1.5 no signal
609 Pulmonary Embolism 104 1.5 1.5 no signal
610 Inappropriate Schedule Of Drug Administration 78 1.5 1.5 no signal
611 Bursitis 13 1.5 1.5 no signal
612 Temperature Intolerance 11 1.5 1.5 no signal
613 Bone Density Decreased 34 1.5 1.5 no signal
614 Dyspnoea 607 1.5 1.5 no signal
615 Blood Cholesterol Increased 50 1.5 1.5 no signal
616 Blood Pressure Systolic Increased 21 1.5 1.5 no signal
617 Mass 15 1.5 1.5 no signal
618 Intentional Product Use Issue 94 1.5 1.5 no signal
619 Speech Disorder 56 1.5 1.5 no signal
620 Rash Generalised 28 1.5 1.5 no signal
621 Hepatic Cytolysis 13 1.5 1.5 no signal
622 Status Epilepticus 12 1.5 1.5 no signal
623 Generalised Oedema 13 1.5 1.5 no signal
624 Tenderness 11 1.5 1.5 no signal
625 Pulmonary Hypertension 22 1.5 1.5 no signal
626 Muscle Tightness 17 1.5 1.5 no signal
627 Somnolence 210 1.5 1.5 no signal
628 Subdural Haematoma 15 1.5 1.5 no signal
629 Restless Legs Syndrome 19 1.5 1.5 no signal
630 Impaired Quality Of Life 15 1.5 1.5 no signal
631 Dizziness Postural 10 1.5 1.5 no signal
632 Neutropenia 141 1.5 1.5 no signal
633 Pneumonitis 28 1.5 1.5 no signal
634 Affect Lability 10 1.5 1.5 no signal
635 Paraesthesia 163 1.5 1.5 no signal
636 Sinus Bradycardia 10 1.5 1.5 no signal
637 Hypokinesia 15 1.5 1.5 no signal
638 Thrombotic Microangiopathy 10 1.5 1.5 no signal
639 Ankle Fracture 16 1.5 1.5 no signal
640 Blood Potassium Decreased 31 1.4 1.4 no signal
641 Eosinophilia 18 1.4 1.4 no signal
642 Acute Hepatic Failure 14 1.4 1.4 no signal
643 Body Temperature Increased 21 1.4 1.4 no signal
644 Haemorrhoids 20 1.4 1.4 no signal
645 Hypersensitivity 188 1.4 1.4 no signal
646 Hypertension 215 1.4 1.4 no signal
647 Rotator Cuff Syndrome 13 1.4 1.4 no signal
648 Skin Ulcer 26 1.4 1.4 no signal
649 Ulcer 16 1.4 1.4 no signal
650 Product Physical Issue 20 1.4 1.4 no signal
651 Blood Pressure Increased 153 1.4 1.4 no signal
652 Carpal Tunnel Syndrome 14 1.4 1.4 no signal
653 Myocardial Infarction 175 1.4 1.4 no signal
654 Presyncope 24 1.4 1.4 no signal
655 Seasonal Allergy 14 1.4 1.4 no signal
656 Hypoglycaemia 48 1.4 1.4 no signal
657 Bone Loss 15 1.4 1.4 no signal
658 Intestinal Obstruction 37 1.4 1.4 no signal
659 Glossodynia 22 1.4 1.4 no signal
660 Initial Insomnia 10 1.4 1.4 no signal
661 Choking 19 1.4 1.4 no signal
662 Drug Level Decreased 10 1.4 1.4 no signal
663 Increased Tendency To Bruise 9 1.4 1.4 no signal
664 Eye Swelling 36 1.4 1.4 no signal
665 Product Packaging Issue 9 1.4 1.4 no signal
666 Delusion 15 1.4 1.4 no signal
667 Middle Insomnia 18 1.4 1.4 no signal
668 Product Taste Abnormal 13 1.4 1.4 no signal
669 Gastrointestinal Haemorrhage 81 1.4 1.4 no signal
670 Acute Respiratory Distress Syndrome 17 1.4 1.4 no signal
671 Gastroenteritis 14 1.4 1.4 no signal
672 Bradycardia 51 1.3 1.4 no signal
673 Nephropathy 9 1.3 1.3 no signal
674 Pericardial Effusion 22 1.3 1.3 no signal
675 Therapeutic Response Unexpected 43 1.3 1.3 no signal
676 Epilepsy 29 1.3 1.3 no signal
677 Seizure 109 1.3 1.3 no signal
678 Type 2 Diabetes Mellitus 32 1.3 1.3 no signal
679 Renal Pain 10 1.3 1.3 no signal
680 Laceration 9 1.3 1.3 no signal
681 Pain 580 1.3 1.3 no signal
682 Sepsis 105 1.3 1.3 no signal
683 Hemiparesis 16 1.3 1.3 no signal
684 International Normalised Ratio Increased 27 1.3 1.3 no signal
685 Rhabdomyolysis 39 1.3 1.3 no signal
686 Impaired Work Ability 20 1.3 1.3 no signal
687 Contraindicated Product Administered 28 1.3 1.3 no signal
688 Vomiting 435 1.3 1.3 no signal
689 Dystonia 18 1.3 1.3 no signal
690 Adrenal Insufficiency 11 1.3 1.3 no signal
691 Flatulence 52 1.3 1.3 no signal
692 Anorexia 12 1.3 1.3 no signal
693 Generalised Tonic-clonic Seizure 15 1.3 1.3 no signal
694 Hepatocellular Injury 13 1.3 1.3 no signal
695 Hypothyroidism 29 1.3 1.3 no signal
696 White Blood Cell Count Increased 35 1.3 1.3 no signal
697 Bronchospasm 13 1.3 1.3 no signal
698 Swelling Face 59 1.3 1.3 no signal
699 Nasal Congestion 53 1.3 1.3 no signal
700 Transaminases Increased 20 1.3 1.3 no signal
701 Lung Disorder 44 1.3 1.3 no signal
702 Migraine 85 1.3 1.3 no signal
703 Ileus 11 1.3 1.3 no signal
704 Skin Irritation 41 1.3 1.3 no signal
705 Skin Discolouration 41 1.3 1.3 no signal
706 Cholestasis 17 1.3 1.3 no signal
707 Dry Throat 9 1.2 1.2 no signal
708 Pneumonia 286 1.2 1.2 no signal
709 Cholelithiasis 29 1.2 1.2 no signal
710 Loss Of Personal Independence In Daily Activities 42 1.2 1.2 no signal
711 Medication Error 49 1.2 1.2 no signal
712 Pharyngitis 11 1.2 1.2 no signal
713 Heart Rate Decreased 31 1.2 1.2 no signal
714 Urinary Incontinence 26 1.2 1.2 no signal
715 Deep Vein Thrombosis 57 1.2 1.2 no signal
716 Lung Neoplasm Malignant 36 1.2 1.2 no signal
717 Urinary Retention 29 1.2 1.2 no signal
718 Iron Deficiency Anaemia 8 1.2 1.2 no signal
719 Neoplasm 10 1.2 1.2 no signal
720 Product Odour Abnormal 9 1.2 1.2 no signal
721 Petechiae 9 1.2 1.2 no signal
722 Gastric Haemorrhage 10 1.2 1.2 no signal
723 Cough 241 1.2 1.2 no signal
724 Drug Reaction With Eosinophilia And Systemic Symptoms 22 1.2 1.2 no signal
725 Amnesia 56 1.2 1.2 no signal
726 Transient Ischaemic Attack 29 1.2 1.2 no signal
727 Diarrhoea Haemorrhagic 8 1.2 1.2 no signal
728 Inappropriate Schedule Of Product Administration 151 1.2 1.2 no signal
729 Weight Increased 189 1.2 1.2 no signal
730 Dehydration 113 1.2 1.2 no signal
731 Diabetes Mellitus Inadequate Control 15 1.2 1.2 no signal
732 Mucosal Inflammation 22 1.2 1.2 no signal
733 Lower Limb Fracture 16 1.2 1.2 no signal
734 Incorrect Dose Administered 188 1.2 1.2 no signal
735 Oedema Peripheral 102 1.2 1.2 no signal
736 Skin Laceration 9 1.2 1.2 no signal
737 Back Injury 9 1.2 1.2 no signal
738 Laryngitis 9 1.2 1.2 no signal
739 Wound 23 1.2 1.2 no signal
740 Liver Injury 20 1.2 1.2 no signal
741 Feeling Cold 23 1.2 1.2 no signal
742 Cerebral Infarction 20 1.1 1.1 no signal
743 Respiratory Tract Congestion 13 1.1 1.1 no signal
744 Angioedema 36 1.1 1.1 no signal
745 Erectile Dysfunction 21 1.1 1.1 no signal
746 Blood Bilirubin Increased 22 1.1 1.1 no signal
747 Hospice Care 8 1.1 1.1 no signal
748 Agranulocytosis 15 1.1 1.1 no signal
749 Hypercalcaemia 10 1.1 1.1 no signal
750 Disability 16 1.1 1.1 no signal
751 Diplopia 21 1.1 1.1 no signal
752 Hypoaesthesia 121 1.1 1.1 no signal
753 Sinus Disorder 16 1.1 1.1 no signal
754 Dysgeusia 60 1.1 1.1 no signal
755 Leukopenia 40 1.1 1.1 no signal
756 Upper Limb Fracture 16 1.1 1.1 no signal
757 Burning Sensation 56 1.1 1.1 no signal
758 Rash Pruritic 43 1.1 1.1 no signal
759 Hypoaesthesia Oral 12 1.1 1.1 no signal
760 Decreased Appetite 184 1.1 1.1 no signal
761 Gastric Ulcer 15 1.1 1.1 no signal
762 Multiple Fractures 13 1.1 1.1 no signal
763 Subarachnoid Haemorrhage 8 1.1 1.1 no signal
764 Infusion Site Pain 10 1.1 1.1 no signal
765 Feeling Hot 48 1.1 1.1 no signal
766 Ear Discomfort 8 1.1 1.1 no signal
767 Lactic Acidosis 25 1.1 1.1 no signal
768 Asthenia 292 1.1 1.1 no signal
769 Rash Macular 27 1.1 1.1 no signal
770 Dermatitis 16 1.1 1.1 no signal
771 Swelling 72 1.1 1.1 no signal
772 Drug Prescribing Error 15 1.1 1.1 no signal
773 Back Pain 178 1.1 1.1 no signal
774 Blood Alkaline Phosphatase Increased 19 1.1 1.1 no signal
775 Thrombocytopenia 85 1.1 1.1 no signal
776 Hospitalisation 116 1.1 1.1 no signal
777 Dysuria 28 1.1 1.1 no signal
778 Ageusia 19 1.1 1.1 no signal
779 Pharmaceutical Product Complaint 20 1.1 1.1 no signal
780 Staphylococcal Infection 25 1.1 1.1 no signal
781 Osteoarthritis 32 1.1 1.1 no signal
782 Diabetic Ketoacidosis 18 1.1 1.1 no signal
783 Lower Respiratory Tract Infection 34 1.1 1.1 no signal
784 Hepatic Encephalopathy 7 1.1 1.1 no signal
785 Sudden Death 8 1.1 1.1 no signal
786 Flank Pain 7 1.1 1.1 no signal
787 Deformity 7 1.0 1.0 no signal
788 Drug Hypersensitivity 144 1.0 1.0 no signal
789 Cerebrovascular Accident 126 1.0 1.0 no signal
790 Haemoglobin Decreased 76 1.0 1.0 no signal
791 Mood Altered 20 1.0 1.0 no signal
792 Fall 244 1.0 1.0 no signal
793 Bone Marrow Failure 15 1.0 1.0 no signal
794 Pulmonary Fibrosis 14 1.0 1.0 no signal
795 Therapy Partial Responder 11 1.0 1.0 no signal
796 Thirst 13 1.0 1.0 no signal
797 Vaginal Haemorrhage 31 1.0 1.0 no signal
798 Blood Glucose Fluctuation 8 1.0 1.0 no signal
799 Tendon Rupture 9 1.0 1.0 no signal
800 Glaucoma 14 1.0 1.0 no signal
801 Peripheral Coldness 10 1.0 1.0 no signal
802 Dermatitis Allergic 9 1.0 1.0 no signal
803 Skin Disorder 24 1.0 1.0 no signal
804 Hypomagnesaemia 10 1.0 1.0 no signal
805 Cystitis 23 1.0 1.0 no signal
806 Liver Function Test Abnormal 21 1.0 1.0 no signal
807 Vision Blurred 98 1.0 1.0 no signal
808 Hip Fracture 23 1.0 1.0 no signal
809 Balance Disorder 62 1.0 1.0 no signal
810 Throat Irritation 32 1.0 1.0 no signal
811 Upper Respiratory Tract Infection 33 1.0 1.0 no signal
812 Pain In Extremity 211 1.0 1.0 no signal
813 Incorrect Route Of Product Administration 12 1.0 1.0 no signal
814 Kidney Infection 14 1.0 1.0 no signal
815 Mouth Ulceration 15 1.0 1.0 no signal
816 Blood Urea Increased 12 1.0 1.0 no signal
817 Rash Papular 16 1.0 1.0 no signal
818 Ligament Sprain 7 1.0 1.0 no signal
819 Bone Disorder 13 1.0 1.0 no signal
820 Rash 306 1.0 1.0 no signal
821 Impaired Gastric Emptying 9 1.0 1.0 no signal
822 Micturition Urgency 8 1.0 1.0 no signal
823 Throat Tightness 19 1.0 1.0 no signal
824 Pancreatitis 37 1.0 1.0 no signal
825 Hepatic Cirrhosis 13 1.0 1.0 no signal
826 Hepatic Failure 21 1.0 1.0 no signal
827 Arrhythmia 33 1.0 1.0 no signal
828 Metastases To Lung 8 1.0 1.0 no signal
829 Motor Dysfunction 7 1.0 1.0 no signal
830 Dyskinesia 28 1.0 1.0 no signal
831 Incorrect Route Of Drug Administration 25 1.0 1.0 no signal
832 Hypocalcaemia 13 1.0 1.0 no signal
833 Abdominal Discomfort 115 1.0 1.0 no signal
834 Diverticulitis 19 1.0 1.0 no signal
835 Sexual Dysfunction 8 1.0 1.0 no signal
836 Multi-organ Failure 12 1.0 1.0 no signal
837 Oedema 37 1.0 1.0 no signal
838 Splenomegaly 8 1.0 1.0 no signal
839 Sensory Disturbance 11 1.0 1.0 no signal
840 Head Discomfort 12 1.0 1.0 no signal
841 Extra Dose Administered 27 1.0 1.0 no signal
842 Hot Flush 51 1.0 1.0 no signal
843 Cholecystitis 8 0.9 0.9 no signal
844 Cardiac Failure 54 0.9 0.9 no signal
845 Cerebral Haemorrhage 24 0.9 0.9 no signal
846 Myalgia 114 0.9 0.9 no signal
847 Haematuria 23 0.9 0.9 no signal
848 Wrist Fracture 8 0.9 0.9 no signal
849 Epistaxis 50 0.9 0.9 no signal
850 Joint Dislocation 7 0.9 0.9 no signal
851 Limb Injury 18 0.9 0.9 no signal
852 Coagulopathy 11 0.9 0.9 no signal
853 Localised Infection 16 0.9 0.9 no signal
854 Urticaria 110 0.9 0.9 no signal
855 Glomerular Filtration Rate Decreased 8 0.9 0.9 no signal
856 Gait Disturbance 126 0.9 0.9 no signal
857 Atrial Fibrillation 64 0.9 0.9 no signal
858 Dysphagia 62 0.9 0.9 no signal
859 Drug Administered At Inappropriate Site 7 0.9 0.9 no signal
860 Cardiac Failure Congestive 53 0.9 0.9 no signal
861 Haematoma 17 0.9 0.9 no signal
862 Abdominal Pain Upper 134 0.9 0.9 no signal
863 Spinal Fracture 13 0.9 0.9 no signal
864 Body Height Decreased 7 0.9 0.9 no signal
865 Wound Infection 7 0.9 0.9 no signal
866 Stomatitis 39 0.9 0.9 no signal
867 Oesophagitis 7 0.9 0.9 no signal
868 Gastrointestinal Pain 7 0.9 0.9 no signal
869 Drug Effect Less Than Expected 9 0.9 0.9 no signal
870 Off Label Use 553 0.9 0.9 no signal
871 Squamous Cell Carcinoma 6 0.9 0.9 no signal
872 Proteinuria 12 0.9 0.9 no signal
873 Drug Intolerance 61 0.9 0.9 no signal
874 Supraventricular Tachycardia 6 0.9 0.9 no signal
875 Abscess 10 0.9 0.9 no signal
876 Pruritus 237 0.9 0.9 no signal
877 Therapy Cessation 32 0.9 0.9 no signal
878 Condition Aggravated 189 0.9 0.9 no signal
879 Post Procedural Complication 12 0.9 0.9 no signal
880 Blood Pressure Fluctuation 15 0.9 0.9 no signal
881 Surgery 36 0.9 0.9 no signal
882 Lymphadenopathy 22 0.9 0.9 no signal
883 Anosmia 9 0.9 0.9 no signal
884 Ear Pain 12 0.9 0.9 no signal
885 Metastases To Bone 10 0.9 0.9 no signal
886 Deafness 16 0.9 0.9 no signal
887 Fluid Overload 9 0.9 0.9 no signal
888 Liver Function Test Increased 13 0.9 0.9 no signal
889 Bedridden 8 0.9 0.9 no signal
890 Joint Injury 13 0.9 0.9 no signal
891 Vertigo 37 0.9 0.9 no signal
892 General Physical Health Deterioration 69 0.8 0.8 no signal
893 Pollakiuria 25 0.8 0.8 no signal
894 Influenza 67 0.8 0.8 no signal
895 Joint Range Of Motion Decreased 8 0.8 0.8 no signal
896 Rash Erythematous 28 0.8 0.8 no signal
897 Activities Of Daily Living Impaired 12 0.8 0.8 no signal
898 Hunger 8 0.8 0.8 no signal
899 Contusion 57 0.8 0.8 no signal
900 Bacterial Infection 11 0.8 0.8 no signal
901 Abdominal Pain Lower 15 0.8 0.8 no signal
902 Fatigue 459 0.8 0.8 no signal
903 Sluggishness 6 0.8 0.8 no signal
904 Night Sweats 19 0.8 0.8 no signal
905 Movement Disorder 19 0.8 0.8 no signal
906 Memory Impairment 81 0.8 0.8 no signal
907 Musculoskeletal Pain 31 0.8 0.8 no signal
908 Tinnitus 27 0.8 0.8 no signal
909 Thrombosis 47 0.8 0.8 no signal
910 Dysstasia 17 0.8 0.8 no signal
911 Laboratory Test Abnormal 17 0.8 0.8 no signal
912 Urinary Tract Infection 98 0.8 0.8 no signal
913 Gastric Disorder 20 0.8 0.8 no signal
914 Hereditary Angioedema 6 0.8 0.8 no signal
915 Alanine Aminotransferase Increased 35 0.8 0.8 no signal
916 Coordination Abnormal 8 0.8 0.8 no signal
917 Blindness Unilateral 8 0.8 0.8 no signal
918 Drug Eruption 10 0.8 0.8 no signal
919 Muscle Spasms 104 0.8 0.8 no signal
920 Local Swelling 10 0.8 0.8 no signal
921 Red Blood Cell Count Decreased 16 0.8 0.8 no signal
922 Sinusitis 57 0.8 0.8 no signal
923 Clostridium Difficile Infection 12 0.8 0.8 no signal
924 Renal Impairment 46 0.8 0.8 no signal
925 Limb Discomfort 17 0.8 0.8 no signal
926 Pulmonary Arterial Hypertension 8 0.8 0.8 no signal
927 Intentional Dose Omission 15 0.8 0.8 no signal
928 Tuberculosis 7 0.8 0.8 no signal
929 Lip Swelling 18 0.8 0.8 no signal
930 Foot Deformity 6 0.8 0.8 no signal
931 Ventricular Fibrillation 6 0.8 0.8 no signal
932 Appendicitis 5 0.8 0.8 no signal
933 Erythema Multiforme 5 0.8 0.8 no signal
934 Photophobia 10 0.8 0.8 no signal
935 Fistula 6 0.7 0.7 no signal
936 Influenza Like Illness 44 0.7 0.7 no signal
937 Aphasia 16 0.7 0.7 no signal
938 Chills 62 0.7 0.7 no signal
939 Aspartate Aminotransferase Increased 28 0.7 0.7 no signal
940 Device Failure 8 0.7 0.7 no signal
941 Diarrhoea 339 0.7 0.7 no signal
942 Musculoskeletal Stiffness 46 0.7 0.7 no signal
943 Osteonecrosis Of Jaw 13 0.7 0.7 no signal
944 Thyroid Disorder 8 0.7 0.7 no signal
945 Eye Disorder 17 0.7 0.7 no signal
946 Illness 52 0.7 0.7 no signal
947 Cognitive Disorder 24 0.7 0.7 no signal
948 Peripheral Swelling 79 0.7 0.7 no signal
949 Irritable Bowel Syndrome 11 0.7 0.7 no signal
950 Eyelid Oedema 6 0.7 0.7 no signal
951 Hypophagia 13 0.7 0.7 no signal
952 Fungal Infection 17 0.7 0.7 no signal
953 Muscular Weakness 58 0.7 0.7 no signal
954 Ill-defined Disorder 31 0.7 0.7 no signal
955 Product Dose Omission Issue 145 0.7 0.7 no signal
956 Neuropathy Peripheral 48 0.7 0.7 no signal
957 Product Use In Unapproved Indication 123 0.7 0.7 no signal
958 Adverse Drug Reaction 45 0.7 0.7 no signal
959 Nephrolithiasis 23 0.7 0.7 no signal
960 Aphonia 7 0.7 0.7 no signal
961 Feeding Disorder 10 0.7 0.7 no signal
962 Prescribed Underdose 10 0.7 0.7 no signal
963 Product Administration Error 10 0.7 0.7 no signal
964 Melaena 11 0.7 0.7 no signal
965 Blood Glucose Decreased 24 0.7 0.7 no signal
966 Therapeutic Response Decreased 30 0.7 0.7 no signal
967 Stevens-johnson Syndrome 11 0.7 0.7 no signal
968 Ear Infection 13 0.7 0.7 no signal
969 Hypoacusis 21 0.7 0.7 no signal
970 Paralysis 7 0.7 0.7 no signal
971 Skin Haemorrhage 7 0.7 0.7 no signal
972 Tooth Extraction 6 0.7 0.7 no signal
973 Jaundice 13 0.7 0.7 no signal
974 Nervous System Disorder 15 0.7 0.7 no signal
975 Extrapyramidal Disorder 12 0.7 0.7 no signal
976 Fracture 9 0.7 0.7 no signal
977 Ocular Hyperaemia 22 0.7 0.7 no signal
978 Product Substitution Issue 27 0.7 0.7 no signal
979 Hernia 9 0.7 0.7 no signal
980 Toxic Epidermal Necrolysis 7 0.7 0.7 no signal
981 Unevaluable Event 35 0.6 0.6 no signal
982 Arthralgia 191 0.6 0.6 no signal
983 Bone Pain 27 0.6 0.6 no signal
984 Haemorrhage 48 0.6 0.6 no signal
985 Pulmonary Thrombosis 5 0.6 0.6 no signal
986 Joint Stiffness 12 0.6 0.6 no signal
987 Tardive Dyskinesia 13 0.6 0.6 no signal
988 Metastases To Liver 8 0.6 0.6 no signal
989 Blood Pressure Abnormal 9 0.6 0.6 no signal
990 Neuralgia 11 0.6 0.6 no signal
991 Cardiac Disorder 42 0.6 0.6 no signal
992 Gallbladder Disorder 8 0.6 0.6 no signal
993 Neutrophil Count Decreased 18 0.6 0.6 no signal
994 Lung Infection 7 0.6 0.6 no signal
995 Blood Glucose Increased 84 0.6 0.6 no signal
996 Chromaturia 10 0.6 0.6 no signal
997 Internal Haemorrhage 5 0.6 0.6 no signal
998 Skin Burning Sensation 31 0.6 0.6 no signal
999 Lacrimation Increased 13 0.6 0.6 no signal
1000 Rhinorrhoea 28 0.6 0.6 no signal
1001 Nerve Compression 4 0.6 0.6 no signal
1002 Adverse Event 40 0.6 0.6 no signal
1003 Dry Eye 21 0.6 0.6 no signal
1004 Arthritis 34 0.6 0.6 no signal
1005 Anaphylactic Shock 11 0.6 0.6 no signal
1006 Back Disorder 7 0.6 0.6 no signal
1007 Spinal Pain 5 0.6 0.6 no signal
1008 Leukaemia 4 0.6 0.6 no signal
1009 Visual Impairment 52 0.6 0.6 no signal
1010 Skin Exfoliation 35 0.6 0.6 no signal
1011 Flushing 43 0.6 0.6 no signal
1012 Accident 5 0.6 0.6 no signal
1013 Blood Urine Present 8 0.6 0.6 no signal
1014 Multiple Sclerosis Relapse 29 0.6 0.6 no signal
1015 Infection 60 0.6 0.6 no signal
1016 Therapy Change 4 0.6 0.6 no signal
1017 Parkinsonism 4 0.6 0.6 no signal
1018 Product Dose Omission In Error 11 0.6 0.6 no signal
1019 Renal Disorder 19 0.6 0.6 no signal
1020 Therapy Non-responder 18 0.6 0.6 no signal
1021 Cyst 5 0.6 0.6 no signal
1022 Ovarian Cyst 4 0.6 0.6 no signal
1023 Full Blood Count Decreased 8 0.6 0.6 no signal
1024 Injection Site Irritation 5 0.6 0.6 no signal
1025 Hip Arthroplasty 6 0.6 0.6 no signal
1026 Arthropathy 22 0.6 0.6 no signal
1027 Platelet Count Decreased 42 0.6 0.6 no signal
1028 Osteonecrosis 13 0.6 0.6 no signal
1029 Poor Venous Access 4 0.5 0.5 no signal
1030 Femur Fracture 12 0.5 0.5 no signal
1031 Injection Site Induration 5 0.5 0.5 no signal
1032 Liver Disorder 17 0.5 0.5 no signal
1033 Unintended Pregnancy 4 0.5 0.5 no signal
1034 Skeletal Injury 4 0.5 0.5 no signal
1035 Discomfort 23 0.5 0.5 no signal
1036 Mobility Decreased 27 0.5 0.5 no signal
1037 Pancytopenia 21 0.5 0.5 no signal
1038 Ascites 11 0.5 0.5 no signal
1039 Fluid Retention 19 0.5 0.5 no signal
1040 Nasopharyngitis 69 0.5 0.5 no signal
1041 Uveitis 5 0.5 0.5 no signal
1042 Hepatic Enzyme Increased 25 0.5 0.5 no signal
1043 Product Packaging Quantity Issue 4 0.5 0.5 no signal
1044 Musculoskeletal Disorder 7 0.5 0.5 no signal
1045 Impaired Healing 12 0.5 0.5 no signal
1046 Viral Infection 12 0.5 0.5 no signal
1047 Nephropathy Toxic 4 0.5 0.5 no signal
1048 Drug Ineffective For Unapproved Indication 20 0.5 0.5 no signal
1049 Eczema 18 0.5 0.5 no signal
1050 Glycosylated Haemoglobin Increased 9 0.5 0.5 no signal
1051 Dialysis 5 0.5 0.5 no signal
1052 Gastric Cancer 9 0.5 0.5 no signal
1053 Joint Swelling 42 0.5 0.5 no signal
1054 Neurotoxicity 6 0.5 0.5 no signal
1055 Product Prescribing Issue 7 0.5 0.5 no signal
1056 White Blood Cell Count Decreased 37 0.5 0.5 no signal
1057 Peritonitis 7 0.5 0.5 no signal
1058 Product Prescribing Error 8 0.5 0.5 no signal
1059 Haemorrhage Intracranial 5 0.5 0.5 no signal
1060 Multiple Sclerosis 16 0.5 0.5 no signal
1061 Drug Effect Decreased 18 0.5 0.5 no signal
1062 Blood Thyroid Stimulating Hormone Increased 3 0.5 0.5 no signal
1063 Psoriatic Arthropathy 13 0.5 0.5 no signal
1064 Lymphoma 5 0.5 0.5 no signal
1065 Metastases To Central Nervous System 4 0.4 0.4 no signal
1066 Accidental Exposure To Product 31 0.4 0.4 no signal
1067 Death 266 0.4 0.4 no signal
1068 Inability To Afford Medication 3 0.4 0.4 no signal
1069 Dry Skin 40 0.4 0.4 no signal
1070 Neoplasm Malignant 20 0.4 0.4 no signal
1071 Injection Site Mass 11 0.4 0.4 no signal
1072 Helicobacter Infection 3 0.4 0.4 no signal
1073 Gastrointestinal Disorder 26 0.4 0.4 no signal
1074 Poor Quality Product Administered 3 0.4 0.4 no signal
1075 Dysphonia 17 0.4 0.4 no signal
1076 Therapy Interrupted 20 0.4 0.4 no signal
1077 Menstruation Delayed 3 0.4 0.4 no signal
1078 Malignant Neoplasm Progression 29 0.4 0.4 no signal
1079 Therapeutic Response Shortened 9 0.4 0.4 no signal
1080 Plasma Cell Myeloma 11 0.4 0.4 no signal
1081 Disease Progression 33 0.4 0.4 no signal
1082 Needle Issue 8 0.4 0.4 no signal
1083 Pelvic Pain 5 0.4 0.4 no signal
1084 Eye Pruritus 9 0.4 0.4 no signal
1085 Blood Glucose Abnormal 5 0.4 0.4 no signal
1086 No Adverse Event 47 0.4 0.4 no signal
1087 Herpes Zoster 15 0.4 0.4 no signal
1088 Acute Myeloid Leukaemia 4 0.4 0.4 no signal
1089 Palmar-plantar Erythrodysaesthesia Syndrome 6 0.4 0.4 no signal
1090 Eye Pain 14 0.4 0.4 no signal
1091 Psoriasis 33 0.4 0.4 no signal
1092 Menorrhagia 5 0.4 0.4 no signal
1093 Covid-19 44 0.3 0.3 no signal
1094 Blindness 10 0.3 0.3 no signal
1095 Injection Site Discolouration 3 0.3 0.3 no signal
1096 Cataract 14 0.3 0.3 no signal
1097 Inflammation 12 0.3 0.3 no signal
1098 Intraocular Pressure Increased 3 0.3 0.3 no signal
1099 Genital Haemorrhage 3 0.3 0.3 no signal
1100 Disease Recurrence 11 0.3 0.3 no signal
1101 Dysmenorrhoea 3 0.3 0.3 no signal
1102 Alopecia 45 0.3 0.3 no signal
1103 Injection Site Pruritus 15 0.3 0.3 no signal
1104 Rheumatoid Arthritis 25 0.3 0.3 no signal
1105 Dermatitis Atopic 11 0.3 0.3 no signal
1106 Prostatic Specific Antigen Increased 3 0.3 0.3 no signal
1107 Hepatic Cancer 5 0.3 0.3 no signal
1108 Injection Site Rash 6 0.3 0.3 no signal
1109 Sickle Cell Anaemia With Crisis 3 0.3 0.3 no signal
1110 Treatment Failure 15 0.3 0.3 no signal
1111 Amenorrhoea 3 0.3 0.3 no signal
1112 Eye Irritation 10 0.3 0.3 no signal
1113 Exposure Via Skin Contact 4 0.2 0.2 no signal
1114 Injection Site Reaction 12 0.2 0.2 no signal
1115 Metrorrhagia 3 0.2 0.2 no signal
1116 Injection Site Pain 46 0.2 0.2 no signal
1117 Injury Associated With Device 3 0.2 0.2 no signal
1118 Circumstance Or Information Capable Of Leading To Medication Error 5 0.2 0.2 no signal
1119 Device Dislocation 6 0.2 0.2 no signal
1120 Device Malfunction 9 0.2 0.2 no signal
1121 Oesophageal Carcinoma 4 0.2 0.2 no signal
1122 Injection Site Swelling 10 0.2 0.2 no signal
1123 Wrong Technique In Device Usage Process 6 0.2 0.2 no signal
1124 Gynaecomastia 4 0.2 0.2 no signal
1125 Acne 9 0.2 0.2 no signal
1126 Device Issue 10 0.2 0.2 no signal
1127 Injection Site Erythema 14 0.2 0.2 no signal
1128 Menstruation Irregular 3 0.2 0.2 no signal
1129 Breast Cancer Female 3 0.2 0.2 no signal
1130 Bladder Cancer 5 0.1 0.1 no signal
1131 Renal Cancer 4 0.1 0.1 no signal
1132 Device Difficult To Use 4 0.1 0.1 no signal
1133 Device Expulsion 3 0.1 0.1 no signal