Drug

Patisiran

60 flagged reaction(s) · 2,043 total co-reports · max PRR 31.2

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Intentional Dose Omission	114	31.2	32.5	signal
2	Infusion Related Reaction	129	14.6	15.3	signal
3	Hospice Care	15	11.4	11.4	signal
4	Poor Venous Access	15	10.9	10.9	signal
5	Product Preparation Error	29	10.5	10.6	signal
6	Cardiac Failure	100	9.3	9.6	signal
7	Therapy Change	12	9.3	9.3	signal
8	Carpal Tunnel Syndrome	16	8.5	8.6	signal
9	Therapy Interrupted	76	8.2	8.4	signal
10	Infusion Site Pain	14	8.2	8.2	signal
11	Insurance Issue	16	8.0	8.1	signal
12	Intercepted Product Preparation Error	13	8.0	8.0	signal
13	Hospitalisation	132	6.5	6.7	signal
14	Polyneuropathy	10	6.3	6.3	signal
15	Generalised Oedema	10	6.1	6.1	signal
16	Product Administration Error	16	6.0	6.0	signal
17	Fluid Overload	11	5.6	5.6	signal
18	Localised Infection	18	5.6	5.6	signal
19	Neuralgia	18	5.5	5.6	signal
20	Malnutrition	8	5.4	5.4	signal
21	Motor Dysfunction	7	5.2	5.2	signal
22	Weight Fluctuation	7	5.0	5.0	signal
23	Ischaemic Stroke	12	5.0	5.0	signal
24	Product Dose Omission	44	5.0	5.0	signal
25	Spinal Operation	8	4.9	4.9	signal
26	Sudden Death	7	4.9	4.9	signal
27	Fluid Retention	33	4.8	4.9	signal
28	Unevaluable Event	48	4.7	4.8	signal
29	Ill-defined Disorder	38	4.7	4.7	signal
30	Product Dose Omission Issue	176	4.6	4.9	signal
31	Blood Pressure Decreased	40	4.5	4.6	signal
32	Medication Error	33	4.4	4.5	signal
33	Orthostatic Hypotension	10	4.3	4.3	signal
34	Dysstasia	16	4.1	4.1	signal
35	Intraocular Pressure Increased	7	4.1	4.1	signal
36	Atrial Fibrillation	51	3.9	4.0	signal
37	Neuropathy Peripheral	49	3.9	3.9	signal
38	Peripheral Coldness	7	3.8	3.8	signal
39	Restless Legs Syndrome	9	3.7	3.7	signal
40	Dialysis	7	3.7	3.7	signal
41	Heart Rate Decreased	17	3.6	3.6	signal
42	Muscle Atrophy	6	3.6	3.6	signal
43	Inappropriate Schedule Of Product Administration	84	3.5	3.6	signal
44	Balance Disorder	41	3.5	3.6	signal
45	Incorrect Product Administration Duration	9	3.3	3.3	signal
46	Impaired Driving Ability	5	3.3	3.3	signal
47	Cardiac Disorder	39	3.1	3.1	signal
48	Injection Site Irritation	5	2.9	3.0	signal
49	Disease Progression	45	2.8	2.9	signal
50	Cholecystectomy	4	2.6	2.6	no signal
51	Leukaemia	3	2.4	2.4	no signal
52	Death	269	2.3	2.5	signal
53	Knee Operation	3	2.3	2.3	no signal
54	Blindness	12	2.2	2.2	signal
55	Cerebrovascular Accident	50	2.2	2.2	signal
56	No Adverse Event	51	2.1	2.2	signal
57	Product Availability Issue	6	2.0	2.0	no signal
58	Hand Deformity	3	1.7	1.7	no signal
59	Prostate Cancer	7	0.6	0.6	no signal
60	Renal Cancer	3	0.5	0.5	no signal