OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pemetrexed Disodium

1,123 flagged reaction(s) · 111,160 total co-reports · max PRR 404.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Pseudocellulitis 89 404.4 405.4 signal
2 Erosive Pustular Dermatosis 20 403.9 404.1 signal
3 Brain Radiation Necrosis 13 126.6 126.6 signal
4 Lung Adenocarcinoma Recurrent 17 122.0 122.0 signal
5 Malignant Neoplasm Oligoprogression 25 92.1 92.2 signal
6 Scleroderma-like Reaction 22 90.9 90.9 signal
7 Autoimmune Lung Disease 16 89.0 89.1 signal
8 Egfr Gene Mutation 49 82.5 82.6 signal
9 Immune-mediated Pneumonitis 29 77.1 77.2 signal
10 Lung Adenocarcinoma Stage Iv 44 72.5 72.6 signal
11 Immune-mediated Lung Disease 191 67.9 68.2 signal
12 Melanoderma 19 66.0 66.0 signal
13 Myocarditis-myositis-myasthenia Gravis Overlap Syndrome 17 57.2 57.2 signal
14 Non-small Cell Lung Cancer Recurrent 26 57.2 57.2 signal
15 Non-small Cell Lung Cancer Metastatic 79 55.9 56.1 signal
16 Immune-mediated Dermatitis 83 53.8 53.9 signal
17 Immune-mediated Renal Disorder 33 51.0 51.0 signal
18 Non-small Cell Lung Cancer 397 50.7 51.2 signal
19 Lung Adenocarcinoma Metastatic 19 48.4 48.4 signal
20 Immune-mediated Gastritis 14 44.9 44.9 signal
21 Autoimmune Nephritis 16 43.8 43.9 signal
22 Acquired Gene Mutation 95 42.9 43.0 signal
23 Bronchial Fistula 14 42.4 42.4 signal
24 Malignant Transformation 31 41.0 41.1 signal
25 Febrile Bone Marrow Aplasia 287 40.7 41.0 signal
26 Hypercreatininaemia 34 40.5 40.5 signal
27 Thrombophlebitis Migrans 22 40.3 40.3 signal
28 Immune-mediated Cholangitis 23 40.1 40.1 signal
29 Immune-mediated Hypothyroidism 71 39.1 39.2 signal
30 Immune-mediated Hepatic Disorder 126 39.0 39.1 signal
31 Radiation Oesophagitis 25 38.9 39.0 signal
32 Dermo-hypodermitis 39 38.9 39.0 signal
33 Immune-mediated Arthritis 24 38.4 38.4 signal
34 Non-small Cell Lung Cancer Stage Iv 23 37.7 37.7 signal
35 Tumour Associated Fever 25 36.8 36.9 signal
36 Immune-mediated Hepatitis 122 36.6 36.7 signal
37 Immune-mediated Nephritis 28 36.4 36.5 signal
38 Immune-mediated Enterocolitis 212 35.4 35.6 signal
39 Tumour Hyperprogression 14 35.0 35.0 signal
40 Tumour Pseudoprogression 64 34.6 34.7 signal
41 Immune-mediated Hyperthyroidism 14 34.4 34.4 signal
42 Lung Adenocarcinoma 174 33.8 34.0 signal
43 Lichenoid Keratosis 125 32.4 32.5 signal
44 Penile Ulceration 18 32.1 32.1 signal
45 Immune-mediated Pancreatitis 20 31.7 31.7 signal
46 Autoimmune Colitis 33 29.9 29.9 signal
47 Metastases To Adrenals 47 29.8 29.8 signal
48 Pleural Mesothelioma Malignant 15 29.7 29.8 signal
49 Myasthenic Syndrome 38 29.0 29.0 signal
50 Lymphangiosis Carcinomatosa 51 28.4 28.5 signal
51 Superior Vena Cava Syndrome 29 27.8 27.8 signal
52 Immune-mediated Myocarditis 73 27.5 27.6 signal
53 Epidermolysis 21 26.6 26.6 signal
54 Immune-mediated Adrenal Insufficiency 34 26.1 26.1 signal
55 Eastern Cooperative Oncology Group Performance Status Worsened 54 25.1 25.1 signal
56 Metastases To The Mediastinum 18 25.0 25.0 signal
57 Radiation Pneumonitis 91 24.5 24.6 signal
58 Nephritis 140 24.4 24.5 signal
59 Paraneoplastic Syndrome 28 23.8 23.8 signal
60 Adrenocorticotropic Hormone Deficiency 36 23.8 23.8 signal
61 Aplasia 81 23.4 23.4 signal
62 Subacute Cutaneous Lupus Erythematosus 71 23.2 23.2 signal
63 Bronchostenosis 22 22.9 23.0 signal
64 Malignant Pleural Effusion 67 22.9 23.0 signal
65 Acute Interstitial Pneumonitis 20 21.9 22.0 signal
66 Immune-mediated Adverse Reaction 55 21.6 21.7 signal
67 Recall Phenomenon 31 21.3 21.3 signal
68 Bronchopleural Fistula 14 21.2 21.2 signal
69 Stasis Dermatitis 25 20.9 20.9 signal
70 Hypophysitis 73 20.8 20.8 signal
71 Skin Toxicity 201 20.7 20.8 signal
72 Bicytopenia 69 20.4 20.5 signal
73 Metastases To Pleura 37 20.4 20.4 signal
74 Radiation Necrosis 20 20.1 20.1 signal
75 Metastases To Meninges 77 19.7 19.7 signal
76 Immune-mediated Encephalitis 17 19.6 19.6 signal
77 Immune-mediated Thyroiditis 16 19.5 19.5 signal
78 Extremity Necrosis 59 19.2 19.2 signal
79 Haematotoxicity 311 19.2 19.3 signal
80 Systemic Scleroderma 23 18.3 18.3 signal
81 Pancytopenia 1,773 18.2 19.0 signal
82 Glucocorticoid Deficiency 13 17.9 17.9 signal
83 Visceral Leishmaniasis 22 17.5 17.5 signal
84 Malignant Neoplasm Progression 3,095 17.3 18.8 signal
85 Secondary Adrenocortical Insufficiency 44 16.7 16.8 signal
86 Hepatic Cytolysis 359 16.7 16.9 signal
87 Aortitis 20 16.7 16.7 signal
88 Hypopituitarism 51 16.7 16.7 signal
89 Oesophagitis Ulcerative 20 16.6 16.6 signal
90 Neutropenic Colitis 60 16.6 16.6 signal
91 Renal Tubular Necrosis 284 16.4 16.6 signal
92 Therapy Partial Responder 431 16.3 16.5 signal
93 Tubulointerstitial Nephritis 530 16.1 16.3 signal
94 Pneumonitis 762 16.0 16.3 signal
95 Gene Mutation 56 16.0 16.1 signal
96 Tracheo-oesophageal Fistula 18 15.9 15.9 signal
97 Paronychia 116 15.2 15.3 signal
98 Hypersensitivity Pneumonitis 30 15.0 15.1 signal
99 Myelosuppression 891 14.9 15.2 signal
100 Pulmonary Artery Thrombosis 20 14.7 14.7 signal
101 Hyperamylasaemia 14 14.5 14.5 signal
102 Tumour Necrosis 26 14.0 14.0 signal
103 Renal Tubular Disorder 70 14.0 14.0 signal
104 Bone Marrow Toxicity 29 13.7 13.7 signal
105 Gastrointestinal Toxicity 113 13.6 13.6 signal
106 Lung Cancer Metastatic 68 13.4 13.4 signal
107 Nephrogenic Diabetes Insipidus 27 13.3 13.3 signal
108 Ototoxicity 43 13.1 13.1 signal
109 Necrotising Myositis 20 13.1 13.1 signal
110 Small Intestinal Perforation 43 12.9 13.0 signal
111 Mucosal Inflammation 589 12.8 13.0 signal
112 Hypertransaminasaemia 152 12.6 12.7 signal
113 Adenocarcinoma 50 12.6 12.6 signal
114 Metastases To Central Nervous System 284 12.5 12.6 signal
115 Lymphadenopathy Mediastinal 42 12.5 12.5 signal
116 Bone Marrow Failure 452 12.5 12.6 signal
117 Radiotherapy 41 12.1 12.1 signal
118 Erysipelas 108 12.1 12.1 signal
119 Nephropathy Toxic 235 11.9 12.0 signal
120 Phimosis 15 11.8 11.8 signal
121 Neutropenic Sepsis 148 11.7 11.7 signal
122 Lymphangitis 16 11.3 11.3 signal
123 Renal Tubular Injury 23 11.2 11.2 signal
124 Aortic Thrombosis 23 11.2 11.2 signal
125 Duodenal Perforation 19 11.0 11.0 signal
126 Pulmonary Toxicity 137 11.0 11.0 signal
127 Carcinoembryonic Antigen Increased 37 10.8 10.8 signal
128 Superinfection Bacterial 15 10.7 10.7 signal
129 Bronchial Carcinoma 15 10.7 10.7 signal
130 Performance Status Decreased 88 10.6 10.6 signal
131 Interstitial Lung Disease 905 10.6 10.8 signal
132 Febrile Neutropenia 1,240 10.5 10.9 signal
133 Fulminant Type 1 Diabetes Mellitus 19 10.5 10.5 signal
134 Granulocyte Count Decreased 32 10.1 10.1 signal
135 Lung Consolidation 49 9.8 9.8 signal
136 Superficial Vein Thrombosis 14 9.8 9.8 signal
137 Haemophagocytic Lymphohistiocytosis 125 9.7 9.8 signal
138 Enteritis 109 9.6 9.7 signal
139 Unmasking Of Previously Unidentified Disease 18 9.4 9.4 signal
140 Large Intestine Infection 20 9.3 9.3 signal
141 Neoplasm Progression 576 9.2 9.3 signal
142 Peripheral Ischaemia 67 9.2 9.2 signal
143 Dermatitis Acneiform 98 9.1 9.1 signal
144 Ocular Toxicity 17 9.0 9.0 signal
145 Myocarditis 181 9.0 9.0 signal
146 Kidney Fibrosis 27 8.8 8.8 signal
147 Pleural Fibrosis 16 8.7 8.7 signal
148 Oesophagitis 166 8.5 8.5 signal
149 Embolism Venous 46 8.5 8.5 signal
150 Adrenal Disorder 29 8.5 8.5 signal
151 Hyperthyroidism 218 8.5 8.5 signal
152 Small Cell Lung Cancer 22 8.4 8.5 signal
153 Embolism Arterial 18 8.4 8.4 signal
154 Cancer Pain 38 8.3 8.3 signal
155 Hypoalbuminaemia 113 8.3 8.3 signal
156 Hepatocellular Injury 209 8.2 8.3 signal
157 Thrombocytopenia 1,630 8.2 8.5 signal
158 Diverticular Perforation 30 8.1 8.1 signal
159 Cholangitis 89 8.1 8.1 signal
160 Systemic Infection 24 8.1 8.1 signal
161 Capillary Leak Syndrome 29 7.9 7.9 signal
162 Myocardial Injury 14 7.9 7.9 signal
163 Magnetic Resonance Imaging Abnormal 16 7.6 7.6 signal
164 Adrenal Insufficiency 161 7.5 7.6 signal
165 Gastrointestinal Perforation 55 7.4 7.4 signal
166 Administration Site Extravasation 13 7.4 7.4 signal
167 Rash Maculo-papular 292 7.4 7.4 signal
168 Creatinine Renal Clearance Decreased 53 7.4 7.4 signal
169 Enterocolitis 75 7.4 7.4 signal
170 Subclavian Vein Thrombosis 15 7.3 7.4 signal
171 Palmar Erythema 15 7.3 7.3 signal
172 Febrile Infection 15 7.3 7.3 signal
173 Prerenal Failure 18 7.2 7.2 signal
174 Neutropenia 1,745 7.2 7.5 signal
175 Colitis 481 7.1 7.2 signal
176 Venous Thrombosis 50 7.1 7.1 signal
177 Neutrophil Count Decreased 512 7.1 7.2 signal
178 Cholangitis Sclerosing 26 7.1 7.1 signal
179 Troponin T Increased 16 7.0 7.0 signal
180 Aspartate Aminotransferase Abnormal 19 7.0 7.0 signal
181 Large Intestine Perforation 87 7.0 7.0 signal
182 Leukopenia 624 7.0 7.1 signal
183 Nephrosclerosis 14 7.0 7.0 signal
184 Metastases To Peritoneum 31 6.9 6.9 signal
185 Encephalitis Autoimmune 16 6.9 6.9 signal
186 Mesothelioma 15 6.9 6.9 signal
187 Mixed Liver Injury 36 6.9 6.9 signal
188 Tumour Pain 16 6.8 6.8 signal
189 Drug Resistance 310 6.8 6.8 signal
190 Vena Cava Thrombosis 20 6.7 6.7 signal
191 Disease Progression 1,399 6.6 6.9 signal
192 Immune Thrombocytopenia 53 6.6 6.6 signal
193 Dermatitis Bullous 85 6.6 6.6 signal
194 Toxic Skin Eruption 119 6.6 6.6 signal
195 Hypothalamo-pituitary Disorder 17 6.6 6.6 signal
196 Cutaneous Lupus Erythematosus 23 6.6 6.6 signal
197 Autoimmune Haemolytic Anaemia 40 6.6 6.6 signal
198 Hepatotoxicity 258 6.5 6.5 signal
199 Monocyte Count Decreased 14 6.5 6.5 signal
200 Haemoptysis 320 6.4 6.4 signal
201 Alanine Aminotransferase Abnormal 24 6.4 6.4 signal
202 Hepatitis Toxic 30 6.4 6.4 signal
203 Immune-mediated Myositis 30 6.4 6.4 signal
204 Bronchial Obstruction 16 6.4 6.4 signal
205 Hypothyroidism 360 6.3 6.4 signal
206 Lung Opacity 29 6.3 6.3 signal
207 Keratitis 34 6.3 6.3 signal
208 Hepatitis 288 6.3 6.3 signal
209 Pleural Effusion 681 6.2 6.3 signal
210 Anaemia 2,133 6.2 6.6 signal
211 Diabetes Insipidus 27 6.2 6.2 signal
212 Toxic Epidermal Necrolysis 168 6.2 6.2 signal
213 Purpura 98 6.2 6.2 signal
214 Thyroiditis 33 6.2 6.2 signal
215 Venous Thrombosis Limb 23 6.1 6.1 signal
216 Autoimmune Hepatitis 76 6.1 6.1 signal
217 Blood Chloride Decreased 28 6.0 6.0 signal
218 Peripheral Motor Neuropathy 15 6.0 6.0 signal
219 N-terminal Prohormone Brain Natriuretic Peptide Increased 15 6.0 6.0 signal
220 Type 1 Diabetes Mellitus 64 5.9 6.0 signal
221 Oral Fungal Infection 29 5.9 5.9 signal
222 Duodenitis 32 5.8 5.8 signal
223 Periorbital Oedema 54 5.8 5.8 signal
224 Anaemia Macrocytic 22 5.8 5.8 signal
225 Non-cardiac Chest Pain 33 5.8 5.8 signal
226 Pulmonary Sepsis 15 5.8 5.8 signal
227 Splenic Infarction 18 5.8 5.8 signal
228 Staphylococcus Test Positive 22 5.8 5.8 signal
229 Multiple-drug Resistance 32 5.8 5.8 signal
230 Metastases To Lung 119 5.8 5.8 signal
231 Arterial Thrombosis 20 5.7 5.7 signal
232 Metastases To Lymph Nodes 69 5.7 5.8 signal
233 Hypoproteinaemia 19 5.7 5.7 signal
234 Pericardial Effusion 234 5.7 5.7 signal
235 Cardiac Tamponade 48 5.6 5.6 signal
236 Hiccups 82 5.6 5.6 signal
237 Dacryostenosis Acquired 13 5.6 5.6 signal
238 Septic Shock 433 5.6 5.6 signal
239 Hypomagnesaemia 139 5.6 5.6 signal
240 Systemic Inflammatory Response Syndrome 38 5.6 5.6 signal
241 Neutrophil Count Abnormal 28 5.5 5.5 signal
242 Dermatitis Exfoliative Generalised 34 5.5 5.5 signal
243 Metastases To Bone 161 5.5 5.5 signal
244 Organising Pneumonia 48 5.5 5.5 signal
245 Hyperpyrexia 40 5.4 5.4 signal
246 Gastrointestinal Necrosis 28 5.4 5.4 signal
247 Haemothorax 28 5.4 5.4 signal
248 Thrombotic Thrombocytopenic Purpura 34 5.4 5.4 signal
249 Proteinuria 181 5.4 5.4 signal
250 Panniculitis 23 5.3 5.3 signal
251 Atelectasis 91 5.2 5.2 signal
252 Leukoencephalopathy 35 5.2 5.2 signal
253 Metastases To Liver 164 5.2 5.2 signal
254 Pneumothorax 147 5.2 5.2 signal
255 Peripheral Sensory Neuropathy 54 5.2 5.2 signal
256 Cytopenia 110 5.1 5.1 signal
257 Alveolitis 13 5.1 5.1 signal
258 Hypocalcaemia 172 5.1 5.1 signal
259 Escherichia Bacteraemia 21 5.1 5.1 signal
260 Cholestasis 173 5.1 5.1 signal
261 Myositis 81 5.0 5.0 signal
262 Embolism 75 5.0 5.0 signal
263 Metastasis 64 5.0 5.0 signal
264 Ischaemia 41 4.9 4.9 signal
265 Disseminated Intravascular Coagulation 124 4.9 4.9 signal
266 Polyarthritis 46 4.9 4.9 signal
267 Pneumoperitoneum 16 4.9 4.9 signal
268 Encephalitis 59 4.8 4.8 signal
269 Lung Infiltration 76 4.8 4.8 signal
270 Acute Kidney Injury 1,299 4.8 4.9 signal
271 Pneumatosis Intestinalis 24 4.7 4.7 signal
272 Duodenal Ulcer Haemorrhage 24 4.7 4.7 signal
273 Adrenocortical Insufficiency Acute 16 4.6 4.6 signal
274 Escherichia Sepsis 24 4.6 4.6 signal
275 Acute Coronary Syndrome 69 4.6 4.6 signal
276 Hepatic Function Abnormal 306 4.6 4.6 signal
277 General Physical Health Deterioration 942 4.6 4.7 signal
278 Transaminases Increased 181 4.5 4.6 signal
279 Metastatic Neoplasm 35 4.5 4.5 signal
280 Optic Neuropathy 17 4.5 4.5 signal
281 Oesophageal Candidiasis 32 4.5 4.5 signal
282 Empyema 16 4.5 4.5 signal
283 Cachexia 41 4.5 4.5 signal
284 Hepatitis Cholestatic 48 4.5 4.5 signal
285 Posterior Reversible Encephalopathy Syndrome 76 4.4 4.5 signal
286 Haemolytic Anaemia 71 4.4 4.4 signal
287 Intestinal Perforation 88 4.4 4.4 signal
288 Vitiligo 18 4.3 4.4 signal
289 Pneumonia Bacterial 71 4.3 4.3 signal
290 Bone Lesion 28 4.3 4.3 signal
291 Chest X-ray Abnormal 24 4.3 4.3 signal
292 Pulmonary Haemorrhage 60 4.3 4.3 signal
293 Respiratory Failure 559 4.3 4.3 signal
294 Blood Albumin Decreased 60 4.2 4.2 signal
295 Hypokalaemia 348 4.2 4.3 signal
296 Cell Death 15 4.2 4.2 signal
297 Ischaemic Stroke 134 4.2 4.2 signal
298 Intestinal Ischaemia 41 4.2 4.2 signal
299 Blood Thyroid Stimulating Hormone Decreased 34 4.2 4.2 signal
300 Neoplasm Recurrence 25 4.1 4.1 signal
301 Inflammatory Marker Increased 36 4.1 4.1 signal
302 Agranulocytosis 135 4.1 4.1 signal
303 Dysaesthesia 22 4.0 4.0 signal
304 Pneumocystis Jirovecii Pneumonia 72 4.0 4.0 signal
305 Rheumatoid Nodule 20 4.0 4.0 signal
306 Subileus 15 4.0 4.0 signal
307 Blood Creatinine Increased 465 4.0 4.0 signal
308 Platelet Count Decreased 755 3.9 4.0 signal
309 Hyperphosphataemia 15 3.9 3.9 signal
310 Aplastic Anaemia 37 3.9 3.9 signal
311 Acute Respiratory Failure 135 3.9 3.9 signal
312 Renal Impairment 589 3.9 4.0 signal
313 Mucosal Dryness 14 3.9 3.9 signal
314 Aplasia Pure Red Cell 24 3.9 3.9 signal
315 Gamma-glutamyltransferase Increased 154 3.9 3.9 signal
316 Metabolic Disorder 40 3.8 3.8 signal
317 Cardiotoxicity 61 3.8 3.8 signal
318 Cytokine Release Syndrome 131 3.8 3.8 signal
319 Scleroderma 25 3.8 3.8 signal
320 Pulmonary Embolism 650 3.8 3.8 signal
321 Hepatitis Acute 44 3.8 3.8 signal
322 Idiopathic Pulmonary Fibrosis 26 3.7 3.7 signal
323 Oesophageal Stenosis 19 3.7 3.7 signal
324 C-reactive Protein Increased 242 3.7 3.7 signal
325 Drug Eruption 117 3.7 3.7 signal
326 Vasculitis 77 3.7 3.7 signal
327 Acute Generalised Exanthematous Pustulosis 51 3.7 3.7 signal
328 Hyperuricaemia 27 3.7 3.7 signal
329 Metastases To Spine 22 3.7 3.7 signal
330 Rash Morbilliform 18 3.6 3.6 signal
331 Brain Natriuretic Peptide Increased 20 3.6 3.6 signal
332 Polyneuropathy 77 3.6 3.6 signal
333 Left Ventricular Dysfunction 43 3.6 3.6 signal
334 Granulocytopenia 37 3.6 3.6 signal
335 Erythema Multiforme 60 3.6 3.6 signal
336 Nephrotic Syndrome 44 3.6 3.6 signal
337 Polymyalgia Rheumatica 20 3.6 3.6 signal
338 Proctitis 18 3.6 3.6 signal
339 Troponin Increased 48 3.5 3.5 signal
340 Urinary Tract Obstruction 15 3.5 3.5 signal
341 Ileus 78 3.5 3.5 signal
342 Tumour Haemorrhage 18 3.5 3.5 signal
343 Stomatitis 381 3.5 3.5 signal
344 Aspartate Aminotransferase Increased 332 3.5 3.5 signal
345 Phlebitis 32 3.5 3.5 signal
346 Acute Respiratory Distress Syndrome 109 3.4 3.4 signal
347 Lichen Planus 14 3.4 3.4 signal
348 Blood Creatine Increased 27 3.4 3.4 signal
349 Bone Marrow Disorder 18 3.3 3.3 signal
350 Osteonecrosis Of Jaw 148 3.3 3.3 signal
351 Cytolytic Hepatitis 20 3.3 3.3 signal
352 Dermatitis Exfoliative 30 3.3 3.3 signal
353 Immune Thrombocytopenic Purpura 17 3.3 3.3 signal
354 Sudden Death 63 3.3 3.3 signal
355 Hypovolaemic Shock 28 3.3 3.3 signal
356 Cerebellar Syndrome 13 3.3 3.3 signal
357 Aphthous Ulcer 45 3.3 3.3 signal
358 Hyponatraemia 329 3.3 3.3 signal
359 Sepsis 649 3.2 3.3 signal
360 Colitis Ischaemic 39 3.2 3.2 signal
361 Pleuritic Pain 16 3.2 3.2 signal
362 Rash Pustular 42 3.2 3.2 signal
363 Oral Candidiasis 74 3.2 3.2 signal
364 Staphylococcal Sepsis 28 3.1 3.1 signal
365 Ileus Paralytic 25 3.1 3.1 signal
366 Anaphylactoid Reaction 23 3.1 3.1 signal
367 Rash Vesicular 27 3.1 3.1 signal
368 Alanine Aminotransferase Increased 344 3.1 3.1 signal
369 Skin Hyperpigmentation 48 3.1 3.1 signal
370 Renal Failure 748 3.1 3.1 signal
371 Protein Total Decreased 21 3.1 3.1 signal
372 Cushingoid 18 3.1 3.1 signal
373 Small Intestinal Obstruction 68 3.1 3.1 signal
374 Dyspnoea At Rest 16 3.1 3.1 signal
375 Pathological Fracture 28 3.1 3.1 signal
376 Pulmonary Fibrosis 105 3.1 3.1 signal
377 Atrial Flutter 44 3.1 3.1 signal
378 White Blood Cell Count Decreased 593 3.0 3.1 signal
379 Amylase Increased 20 3.0 3.0 signal
380 Thoracic Vertebral Fracture 16 3.0 3.0 signal
381 Cerebral Ischaemia 28 3.0 3.0 signal
382 Ventricular Dysfunction 14 3.0 3.0 signal
383 Drug-induced Liver Injury 166 3.0 3.0 signal
384 Blood Urea Increased 90 3.0 3.0 signal
385 Ascites 157 3.0 3.0 signal
386 Exfoliative Rash 14 3.0 3.0 signal
387 Hepatic Lesion 23 3.0 3.0 signal
388 Glomerulonephritis 13 3.0 3.0 signal
389 Electrolyte Imbalance 60 2.9 2.9 signal
390 Thrombocytosis 19 2.9 2.9 signal
391 Lip Oedema 22 2.9 2.9 signal
392 Hyperthermia 39 2.9 2.9 signal
393 Hypoxia 179 2.8 2.8 signal
394 Clonus 14 2.8 2.8 signal
395 Retinopathy 19 2.8 2.8 signal
396 Odynophagia 30 2.8 2.8 signal
397 Peritonitis 105 2.8 2.8 signal
398 Arteriospasm Coronary 20 2.8 2.8 signal
399 Fibrin D Dimer Increased 18 2.8 2.8 signal
400 Diverticulum Intestinal 22 2.8 2.8 signal
401 Malnutrition 56 2.8 2.8 signal
402 Pleurisy 30 2.8 2.8 signal
403 Renal Function Test Abnormal 23 2.8 2.8 signal
404 Drug Tolerance Decreased 14 2.8 2.8 signal
405 Normochromic Normocytic Anaemia 15 2.8 2.8 signal
406 Failure To Thrive 26 2.8 2.8 signal
407 Acute Pulmonary Oedema 28 2.8 2.8 signal
408 Blood Culture Positive 15 2.7 2.8 signal
409 Mouth Ulceration 104 2.7 2.8 signal
410 Second Primary Malignancy 41 2.7 2.7 signal
411 Renal Failure Acute 212 2.7 2.7 signal
412 Haematocrit Decreased 98 2.7 2.7 signal
413 Arteriosclerosis 46 2.7 2.7 signal
414 Dehydration 650 2.7 2.7 signal
415 Blood Magnesium Decreased 42 2.7 2.7 signal
416 Pericarditis 81 2.7 2.7 signal
417 Tearfulness 21 2.7 2.7 signal
418 Pemphigoid 36 2.7 2.7 signal
419 Face Oedema 81 2.7 2.7 signal
420 Blood Lactate Dehydrogenase Increased 76 2.6 2.6 signal
421 Hypophosphataemia 35 2.6 2.6 signal
422 Localised Oedema 22 2.6 2.6 signal
423 Infusion Related Reaction 312 2.6 2.6 signal
424 General Physical Condition Abnormal 32 2.6 2.6 signal
425 Brain Oedema 59 2.6 2.6 signal
426 Stevens-johnson Syndrome 104 2.6 2.6 signal
427 Blood Alkaline Phosphatase Increased 116 2.6 2.6 signal
428 Cerebral Infarction 114 2.6 2.6 signal
429 Necrosis 26 2.6 2.6 signal
430 Peripheral Arterial Occlusive Disease 19 2.6 2.6 signal
431 Multi-organ Failure 81 2.6 2.6 signal
432 Compression Fracture 24 2.6 2.6 signal
433 Spinal Cord Compression 18 2.6 2.6 signal
434 Respiratory Distress 127 2.6 2.6 signal
435 Decreased Appetite 1,065 2.6 2.6 signal
436 Epigastric Discomfort 18 2.5 2.5 signal
437 Lymphocyte Count Decreased 81 2.5 2.5 signal
438 Epistaxis 343 2.5 2.6 signal
439 Guillain-barre Syndrome 22 2.5 2.5 signal
440 Liver Injury 110 2.5 2.5 signal
441 Duodenal Ulcer 32 2.5 2.5 signal
442 Thrombophlebitis 16 2.5 2.5 signal
443 Petechiae 47 2.5 2.5 signal
444 Optic Ischaemic Neuropathy 16 2.5 2.5 signal
445 Gastric Ulcer Haemorrhage 25 2.5 2.5 signal
446 Blood Creatinine Decreased 14 2.5 2.5 signal
447 Fluid Intake Reduced 22 2.5 2.5 signal
448 Hypovolaemia 26 2.5 2.5 signal
449 Blood Thyroid Stimulating Hormone Increased 41 2.5 2.5 signal
450 Anorexia 58 2.5 2.5 signal
451 Anaphylactic Shock 113 2.4 2.5 signal
452 Neutrophilia 25 2.4 2.4 signal
453 Dermatitis 91 2.4 2.4 signal
454 Skin Erosion 14 2.4 2.4 signal
455 Nephropathy 41 2.4 2.4 signal
456 Hypophagia 110 2.4 2.4 signal
457 Thrombotic Microangiopathy 42 2.4 2.4 signal
458 Herpes Virus Infection 25 2.4 2.4 signal
459 Circulatory Collapse 74 2.4 2.4 signal
460 Pulmonary Alveolar Haemorrhage 24 2.4 2.4 signal
461 Deep Vein Thrombosis 279 2.4 2.4 signal
462 Blood Sodium Decreased 80 2.4 2.4 signal
463 Inappropriate Antidiuretic Hormone Secretion 43 2.3 2.3 signal
464 Oedema 227 2.3 2.3 signal
465 Myasthenia Gravis 33 2.3 2.3 signal
466 Papilloedema 19 2.3 2.3 signal
467 Lung Neoplasm 18 2.3 2.3 signal
468 Supraventricular Tachycardia 40 2.3 2.3 signal
469 Emphysema 42 2.3 2.3 signal
470 Cardiogenic Shock 59 2.3 2.3 signal
471 Wound Dehiscence 14 2.3 2.3 signal
472 Lung Disorder 202 2.3 2.3 signal
473 Lymphoedema 28 2.3 2.3 signal
474 Breath Sounds Abnormal 20 2.2 2.2 signal
475 Acute Myeloid Leukaemia 63 2.2 2.2 signal
476 Bronchopneumonia 14 2.2 2.2 signal
477 Hyperkalaemia 139 2.2 2.2 signal
478 Skin Reaction 56 2.2 2.2 signal
479 Conjunctivitis 73 2.2 2.2 signal
480 Pulmonary Mass 59 2.2 2.2 signal
481 Lumbar Vertebral Fracture 18 2.2 2.2 signal
482 Flank Pain 37 2.2 2.2 signal
483 Haemoglobin Decreased 406 2.2 2.2 signal
484 Endocarditis 20 2.2 2.2 signal
485 Pneumonia 1,259 2.2 2.2 signal
486 Neutrophil Count Increased 40 2.2 2.2 signal
487 Meningitis 26 2.2 2.2 signal
488 Dyspnoea Exertional 146 2.2 2.2 signal
489 Oesophageal Ulcer 15 2.2 2.2 signal
490 Cardiomyopathy 57 2.1 2.1 signal
491 Blood Uric Acid Increased 22 2.1 2.1 signal
492 Blood Calcium Decreased 43 2.1 2.1 signal
493 Muscle Fatigue 16 2.1 2.1 signal
494 Blood Bilirubin Increased 102 2.1 2.1 signal
495 Bronchopulmonary Aspergillosis 29 2.1 2.1 signal
496 Oedema Peripheral 459 2.1 2.1 signal
497 Lung Neoplasm Malignant 155 2.1 2.1 signal
498 Diarrhoea Haemorrhagic 35 2.1 2.1 signal
499 Multiple Organ Dysfunction Syndrome 104 2.1 2.1 signal
500 Pyrexia 1,283 2.1 2.1 signal
501 Recurrent Cancer 15 2.1 2.1 signal
502 Candidiasis 15 2.0 2.0 signal
503 Lung Infection 58 2.0 2.0 signal
504 Faecaloma 20 2.0 2.0 signal
505 Sarcoidosis 17 2.0 2.0 no signal
506 Meningitis Aseptic 16 2.0 2.0 no signal
507 Generalised Oedema 44 2.0 2.0 no signal
508 Red Blood Cell Count Decreased 102 2.0 2.0 no signal
509 Lacrimation Increased 106 2.0 2.0 no signal
510 Hepatic Failure 107 2.0 2.0 no signal
511 Cholecystitis 42 2.0 2.0 no signal
512 Neurological Symptom 20 2.0 2.0 no signal
513 Acute Myocardial Infarction 104 1.9 2.0 no signal
514 Atrial Fibrillation 341 1.9 1.9 no signal
515 Hydronephrosis 26 1.9 1.9 no signal
516 Platelet Count Abnormal 21 1.9 1.9 no signal
517 Staphylococcal Bacteraemia 15 1.9 1.9 no signal
518 Cardiac Failure Acute 23 1.9 1.9 no signal
519 Stress Cardiomyopathy 20 1.9 1.9 no signal
520 Hospice Care 34 1.9 1.9 no signal
521 Melaena 76 1.9 1.9 no signal
522 Haemoglobin Abnormal 22 1.9 1.9 no signal
523 Lupus-like Syndrome 31 1.9 1.9 no signal
524 Liver Disorder 152 1.9 1.9 no signal
525 Leukocytosis 62 1.9 1.9 no signal
526 Eyelid Oedema 40 1.9 1.9 no signal
527 Extravasation 14 1.9 1.9 no signal
528 Pancreatitis Acute 75 1.9 1.9 no signal
529 Prothrombin Time Prolonged 20 1.8 1.8 no signal
530 Pneumonia Aspiration 82 1.8 1.8 no signal
531 Skin Disorder 109 1.8 1.8 no signal
532 Diverticulitis 89 1.8 1.8 no signal
533 Neuropathy Peripheral 304 1.8 1.8 no signal
534 Platelet Count Increased 42 1.8 1.8 no signal
535 Respiratory Tract Infection 82 1.8 1.8 no signal
536 Cellulitis 159 1.7 1.8 no signal
537 Asthenia 1,182 1.7 1.8 no signal
538 White Blood Cell Count Abnormal 20 1.7 1.7 no signal
539 Lymphopenia 44 1.7 1.7 no signal
540 Neurotoxicity 54 1.7 1.7 no signal
541 Trismus 16 1.7 1.7 no signal
542 Pigmentation Disorder 19 1.7 1.7 no signal
543 Congestive Cardiomyopathy 13 1.7 1.7 no signal
544 Sinus Tachycardia 43 1.7 1.7 no signal
545 Vomiting 1,417 1.7 1.7 no signal
546 Hypernatraemia 15 1.7 1.7 no signal
547 Ejection Fraction Decreased 47 1.7 1.7 no signal
548 Clostridium Difficile Colitis 32 1.7 1.7 no signal
549 Gastritis 79 1.7 1.7 no signal
550 Hemiplegia 25 1.7 1.7 no signal
551 Skin Abrasion 14 1.7 1.7 no signal
552 Cardiac Failure 239 1.6 1.7 no signal
553 Rash 1,289 1.6 1.7 no signal
554 Haemodynamic Instability 22 1.6 1.6 no signal
555 Hypercalcaemia 36 1.6 1.6 no signal
556 Dysphagia 276 1.6 1.6 no signal
557 Oliguria 18 1.6 1.6 no signal
558 Lipase Increased 22 1.6 1.6 no signal
559 Ventricular Fibrillation 32 1.6 1.6 no signal
560 Bronchospasm 41 1.6 1.6 no signal
561 Constipation 619 1.6 1.6 no signal
562 Thyroid Disorder 44 1.6 1.6 no signal
563 Pancreatic Disorder 14 1.6 1.6 no signal
564 Diarrhoea 1,824 1.6 1.6 no signal
565 Spinal Osteoarthritis 25 1.6 1.6 no signal
566 Shock Haemorrhagic 23 1.6 1.6 no signal
567 Lower Gastrointestinal Haemorrhage 21 1.6 1.6 no signal
568 Cholecystitis Acute 16 1.6 1.6 no signal
569 Protein Urine Present 14 1.6 1.6 no signal
570 Folliculitis 29 1.6 1.6 no signal
571 Eosinophilia 49 1.6 1.6 no signal
572 Anaphylactic Reaction 154 1.6 1.6 no signal
573 Therapeutic Product Effect Incomplete 198 1.6 1.6 no signal
574 Haematemesis 71 1.5 1.5 no signal
575 Myocardial Ischaemia 32 1.5 1.5 no signal
576 Cheilitis 15 1.5 1.5 no signal
577 Mental Status Changes 77 1.5 1.5 no signal
578 Cardio-respiratory Arrest 116 1.5 1.5 no signal
579 Subarachnoid Haemorrhage 28 1.5 1.5 no signal
580 Gastric Ulcer 52 1.5 1.5 no signal
581 Cyanosis 43 1.5 1.5 no signal
582 Rash Pruritic 147 1.5 1.5 no signal
583 Ventricular Tachycardia 45 1.5 1.5 no signal
584 White Blood Cell Count Increased 104 1.5 1.5 no signal
585 Gastrointestinal Inflammation 21 1.5 1.5 no signal
586 Ventricular Extrasystoles 28 1.5 1.5 no signal
587 Off Label Use 2,318 1.5 1.5 no signal
588 Arterial Occlusive Disease 21 1.5 1.5 no signal
589 Angiopathy 15 1.5 1.5 no signal
590 Eyelid Ptosis 27 1.5 1.5 no signal
591 Squamous Cell Carcinoma 25 1.5 1.5 no signal
592 Gingival Bleeding 36 1.5 1.5 no signal
593 Hyperbilirubinaemia 27 1.5 1.5 no signal
594 Blood Disorder 21 1.5 1.5 no signal
595 Abdominal Tenderness 13 1.4 1.4 no signal
596 Hyperglycaemia 95 1.4 1.5 no signal
597 Drug Toxicity 36 1.4 1.4 no signal
598 Neoplasm 30 1.4 1.4 no signal
599 Ataxia 31 1.4 1.4 no signal
600 Laryngeal Oedema 16 1.4 1.4 no signal
601 Refusal Of Treatment By Patient 17 1.4 1.4 no signal
602 Mouth Haemorrhage 19 1.4 1.4 no signal
603 Musculoskeletal Chest Pain 40 1.4 1.4 no signal
604 Liver Function Test Increased 55 1.4 1.4 no signal
605 Palmar-plantar Erythrodysaesthesia Syndrome 60 1.4 1.4 no signal
606 Polyuria 21 1.4 1.4 no signal
607 Upper Gastrointestinal Haemorrhage 43 1.4 1.4 no signal
608 Encephalopathy 62 1.4 1.4 no signal
609 Liver Function Test Abnormal 74 1.4 1.4 no signal
610 Lymphadenopathy 89 1.4 1.4 no signal
611 Oxygen Saturation Decreased 140 1.4 1.4 no signal
612 Skin Infection 28 1.4 1.4 no signal
613 Aspergillus Infection 16 1.4 1.4 no signal
614 Orthostatic Hypotension 43 1.4 1.4 no signal
615 Bacteraemia 29 1.4 1.4 no signal
616 Decubitus Ulcer 20 1.4 1.4 no signal
617 Tachypnoea 33 1.3 1.3 no signal
618 Hepatomegaly 24 1.3 1.3 no signal
619 Delirium 84 1.3 1.3 no signal
620 Generalised Erythema 14 1.3 1.3 no signal
621 Arteriosclerosis Coronary Artery 16 1.3 1.3 no signal
622 Tachycardia 215 1.3 1.3 no signal
623 Nausea 1,906 1.3 1.4 no signal
624 Atrioventricular Block Complete 16 1.3 1.3 no signal
625 Renal Cyst 19 1.3 1.3 no signal
626 Diabetic Ketoacidosis 57 1.3 1.3 no signal
627 Dyspnoea 1,339 1.3 1.3 no signal
628 Shock 54 1.3 1.3 no signal
629 Respiratory Rate Increased 21 1.3 1.3 no signal
630 Covid-19 Pneumonia 28 1.3 1.3 no signal
631 Acute Hepatic Failure 32 1.3 1.3 no signal
632 Proctalgia 15 1.3 1.3 no signal
633 Gastroenteritis 34 1.3 1.3 no signal
634 Renal Disorder 107 1.3 1.3 no signal
635 Right Ventricular Failure 16 1.3 1.3 no signal
636 Infection 326 1.3 1.3 no signal
637 Glomerular Filtration Rate Decreased 27 1.2 1.2 no signal
638 Acidosis 17 1.2 1.2 no signal
639 Candida Infection 37 1.2 1.2 no signal
640 Epilepsy 67 1.2 1.2 no signal
641 Adverse Reaction 29 1.2 1.2 no signal
642 Tumour Lysis Syndrome 19 1.2 1.2 no signal
643 Productive Cough 102 1.2 1.2 no signal
644 Appetite Disorder 14 1.2 1.2 no signal
645 Hypotension 430 1.2 1.2 no signal
646 Spinal Pain 25 1.2 1.2 no signal
647 Chronic Obstructive Pulmonary Disease 111 1.2 1.2 no signal
648 Body Temperature Decreased 21 1.2 1.2 no signal
649 Rash Erythematous 99 1.2 1.2 no signal
650 Hemiparesis 36 1.2 1.2 no signal
651 Bronchiectasis 14 1.2 1.2 no signal
652 Rash Generalised 55 1.2 1.2 no signal
653 Nail Disorder 18 1.1 1.1 no signal
654 Abnormal Loss Of Weight 14 1.1 1.1 no signal
655 Groin Pain 18 1.1 1.1 no signal
656 Haematuria 70 1.1 1.1 no signal
657 Status Epilepticus 23 1.1 1.1 no signal
658 Scab 23 1.1 1.1 no signal
659 Tricuspid Valve Incompetence 16 1.1 1.1 no signal
660 Gastrointestinal Disorder 177 1.1 1.1 no signal
661 Erythema 406 1.1 1.1 no signal
662 Immune System Disorder 26 1.1 1.1 no signal
663 Death 1,688 1.1 1.1 no signal
664 Urosepsis 18 1.1 1.1 no signal
665 Rectal Haemorrhage 84 1.1 1.1 no signal
666 Urine Output Decreased 17 1.1 1.1 no signal
667 Syncope 192 1.1 1.1 no signal
668 Oral Pain 43 1.1 1.1 no signal
669 Cognitive Disorder 89 1.1 1.1 no signal
670 Skin Lesion 52 1.1 1.1 no signal
671 Pulmonary Oedema 84 1.0 1.0 no signal
672 Optic Neuritis 17 1.0 1.0 no signal
673 Fatigue 1,444 1.0 1.0 no signal
674 Jaundice 50 1.0 1.0 no signal
675 Dysgeusia 138 1.0 1.0 no signal
676 Myopathy 16 1.0 1.0 no signal
677 Aspiration 20 1.0 1.0 no signal
678 Dermatitis Allergic 23 1.0 1.0 no signal
679 Diffuse Large B-cell Lymphoma 14 1.0 1.0 no signal
680 Escherichia Infection 15 1.0 1.0 no signal
681 Appendicitis 17 1.0 1.0 no signal
682 Disease Recurrence 87 1.0 1.0 no signal
683 Device Related Infection 28 1.0 1.0 no signal
684 Altered State Of Consciousness 39 1.0 1.0 no signal
685 Haemolysis 14 1.0 1.0 no signal
686 Cytomegalovirus Infection 30 1.0 1.0 no signal
687 Cardiac Arrest 149 1.0 1.0 no signal
688 Renal Failure Chronic 14 1.0 1.0 no signal
689 Blood Potassium Decreased 54 1.0 1.0 no signal
690 Hypertension 378 1.0 1.0 no signal
691 Bone Pain 104 1.0 1.0 no signal
692 Chest Pain 328 1.0 1.0 no signal
693 Deafness 46 1.0 1.0 no signal
694 Abdominal Pain 403 1.0 1.0 no signal
695 Immunosuppression 15 1.0 1.0 no signal
696 Myelodysplastic Syndrome 25 1.0 1.0 no signal
697 Musculoskeletal Pain 91 1.0 1.0 no signal
698 Pancreatitis 91 1.0 1.0 no signal
699 Toxicity To Various Agents 288 0.9 0.9 no signal
700 Carpal Tunnel Syndrome 24 0.9 0.9 no signal
701 Angina Pectoris 49 0.9 0.9 no signal
702 Blood Creatine Phosphokinase Increased 49 0.9 0.9 no signal
703 Cough 467 0.9 0.9 no signal
704 Confusional State 270 0.9 0.9 no signal
705 Spinal Compression Fracture 14 0.9 0.9 no signal
706 Blood Potassium Increased 27 0.9 0.9 no signal
707 Drug Intolerance 160 0.9 0.9 no signal
708 Skin Plaque 14 0.9 0.9 no signal
709 Inflammation 85 0.9 0.9 no signal
710 Diplopia 43 0.9 0.9 no signal
711 Pseudomonas Infection 14 0.9 0.9 no signal
712 Retinal Detachment 15 0.9 0.9 no signal
713 Immunodeficiency 24 0.9 0.9 no signal
714 Pulmonary Hypertension 34 0.9 0.9 no signal
715 Pyelonephritis 14 0.9 0.9 no signal
716 Hepatic Encephalopathy 15 0.9 0.9 no signal
717 Myoclonus 19 0.9 0.9 no signal
718 Rebound Effect 18 0.9 0.9 no signal
719 Hypothermia 16 0.9 0.9 no signal
720 Haemorrhage 164 0.9 0.9 no signal
721 Dysarthria 59 0.9 0.9 no signal
722 Urinary Retention 51 0.8 0.8 no signal
723 Gastrointestinal Haemorrhage 128 0.8 0.8 no signal
724 Central Nervous System Lesion 21 0.8 0.8 no signal
725 Body Temperature Increased 31 0.8 0.8 no signal
726 Coagulopathy 25 0.8 0.8 no signal
727 Weight Decreased 419 0.8 0.8 no signal
728 Blood Count Abnormal 23 0.8 0.8 no signal
729 Intestinal Obstruction 56 0.8 0.8 no signal
730 Gastric Haemorrhage 17 0.8 0.8 no signal
731 Therapy Non-responder 65 0.8 0.8 no signal
732 Nodule 19 0.8 0.8 no signal
733 Bacterial Infection 27 0.8 0.8 no signal
734 Metabolic Acidosis 46 0.8 0.8 no signal
735 Poor Quality Sleep 31 0.8 0.8 no signal
736 Product Use In Unapproved Indication 353 0.8 0.8 no signal
737 Respiratory Disorder 43 0.8 0.8 no signal
738 Drug Interaction 227 0.8 0.8 no signal
739 Rash Papular 32 0.8 0.8 no signal
740 International Normalised Ratio Increased 41 0.8 0.8 no signal
741 Staphylococcal Infection 47 0.8 0.8 no signal
742 Mitral Valve Incompetence 16 0.8 0.8 no signal
743 Thrombosis 114 0.8 0.8 no signal
744 Presyncope 34 0.8 0.8 no signal
745 Muscular Weakness 159 0.8 0.8 no signal
746 Hypotonia 14 0.8 0.8 no signal
747 Neoplasm Malignant 93 0.8 0.8 no signal
748 Rash Macular 48 0.8 0.8 no signal
749 Chronic Kidney Disease 105 0.8 0.8 no signal
750 Blood Urine Present 26 0.8 0.8 no signal
751 Skin Ulcer 35 0.8 0.7 no signal
752 Chills 159 0.7 0.7 no signal
753 Chest Discomfort 138 0.7 0.7 no signal
754 Sinus Bradycardia 13 0.7 0.7 no signal
755 Uveitis 18 0.7 0.7 no signal
756 Skin Discolouration 61 0.7 0.7 no signal
757 Tinnitus 61 0.7 0.7 no signal
758 Condition Aggravated 398 0.7 0.7 no signal
759 Flushing 134 0.7 0.7 no signal
760 Vertigo 79 0.7 0.7 no signal
761 Hepatic Enzyme Increased 88 0.7 0.7 no signal
762 Tendon Rupture 16 0.7 0.7 no signal
763 Prescribed Overdose 25 0.7 0.7 no signal
764 Aphasia 39 0.7 0.7 no signal
765 Mass 18 0.7 0.7 no signal
766 Pulmonary Congestion 17 0.7 0.7 no signal
767 Chromaturia 29 0.7 0.7 no signal
768 Pulmonary Thrombosis 14 0.7 0.7 no signal
769 Dysuria 47 0.7 0.7 no signal
770 Muscle Atrophy 16 0.7 0.7 no signal
771 Angioedema 56 0.7 0.7 no signal
772 Dysphonia 74 0.7 0.7 no signal
773 Depressed Level Of Consciousness 50 0.7 0.7 no signal
774 Ulcer 20 0.7 0.7 no signal
775 Hyperlipidaemia 15 0.7 0.7 no signal
776 Incorrect Route Of Product Administration 21 0.7 0.7 no signal
777 Cerebrovascular Accident 212 0.7 0.7 no signal
778 Blood Pressure Decreased 82 0.7 0.7 no signal
779 Pulmonary Arterial Hypertension 18 0.7 0.7 no signal
780 Pain In Jaw 35 0.7 0.7 no signal
781 Diabetes Mellitus 94 0.7 0.7 no signal
782 Retching 26 0.7 0.7 no signal
783 Photosensitivity Reaction 20 0.7 0.7 no signal
784 Drug Reaction With Eosinophilia And Systemic Symptoms 31 0.7 0.7 no signal
785 Taste Disorder 24 0.7 0.7 no signal
786 Ocular Discomfort 13 0.7 0.7 no signal
787 Skin Exfoliation 99 0.7 0.7 no signal
788 Flatulence 67 0.7 0.7 no signal
789 Hepatic Steatosis 22 0.7 0.7 no signal
790 Treatment Failure 97 0.7 0.7 no signal
791 Coronary Artery Disease 36 0.7 0.7 no signal
792 Herpes Zoster 67 0.6 0.6 no signal
793 Musculoskeletal Discomfort 20 0.6 0.6 no signal
794 Generalised Tonic-clonic Seizure 19 0.6 0.6 no signal
795 Ageusia 29 0.6 0.6 no signal
796 Back Pain 269 0.6 0.6 no signal
797 Tenderness 12 0.6 0.6 no signal
798 Dizziness Postural 11 0.6 0.6 no signal
799 Post Procedural Complication 22 0.6 0.6 no signal
800 Myocardial Infarction 201 0.6 0.6 no signal
801 Cardiomegaly 14 0.6 0.6 no signal
802 Cholelithiasis 37 0.6 0.6 no signal
803 Urinary Tract Infection 190 0.6 0.6 no signal
804 Subdural Haematoma 16 0.6 0.6 no signal
805 Eczema 56 0.6 0.6 no signal
806 Neuralgia 27 0.6 0.6 no signal
807 Blindness 45 0.6 0.6 no signal
808 Feeding Disorder 22 0.6 0.6 no signal
809 Wheezing 65 0.6 0.6 no signal
810 Pruritus 415 0.6 0.6 no signal
811 Full Blood Count Decreased 22 0.6 0.6 no signal
812 Motor Dysfunction 11 0.6 0.6 no signal
813 Nervous System Disorder 34 0.6 0.6 no signal
814 Adverse Event 100 0.6 0.6 no signal
815 Lower Respiratory Tract Infection 49 0.6 0.6 no signal
816 Obstructive Airways Disorder 12 0.6 0.6 no signal
817 Loss Of Personal Independence In Daily Activities 51 0.6 0.6 no signal
818 Convulsion 62 0.6 0.6 no signal
819 Malaise 465 0.6 0.6 no signal
820 Disorientation 42 0.6 0.6 no signal
821 Seizure 121 0.6 0.6 no signal
822 Arrhythmia 50 0.6 0.6 no signal
823 Hypoacusis 45 0.6 0.6 no signal
824 Incontinence 11 0.6 0.6 no signal
825 Bone Disorder 19 0.6 0.6 no signal
826 Hypersensitivity 191 0.6 0.6 no signal
827 Paraesthesia 162 0.6 0.6 no signal
828 Abdominal Pain Lower 26 0.6 0.6 no signal
829 Upper Respiratory Tract Infection 47 0.6 0.6 no signal
830 Local Swelling 18 0.6 0.6 no signal
831 Back Injury 11 0.6 0.6 no signal
832 Coronary Artery Occlusion 14 0.6 0.6 no signal
833 Unresponsive To Stimuli 26 0.6 0.6 no signal
834 Osteoporosis 41 0.6 0.6 no signal
835 Toothache 18 0.6 0.6 no signal
836 Muscle Tightness 16 0.5 0.5 no signal
837 Dialysis 14 0.5 0.5 no signal
838 Eating Disorder 21 0.5 0.5 no signal
839 Cerebral Haemorrhage 35 0.5 0.5 no signal
840 Oropharyngeal Pain 90 0.5 0.5 no signal
841 Product Use Issue 180 0.5 0.5 no signal
842 Therapeutic Response Decreased 58 0.5 0.5 no signal
843 Inappropriate Schedule Of Product Administration 170 0.5 0.5 no signal
844 Fungal Infection 32 0.5 0.5 no signal
845 Fluid Overload 14 0.5 0.5 no signal
846 Electrocardiogram Qt Prolonged 34 0.5 0.5 no signal
847 Osteomyelitis 17 0.5 0.5 no signal
848 Rhabdomyolysis 39 0.5 0.5 no signal
849 Alopecia 184 0.5 0.5 no signal
850 Respiratory Arrest 26 0.5 0.5 no signal
851 Device Occlusion 13 0.5 0.5 no signal
852 Systemic Lupus Erythematosus 33 0.5 0.5 no signal
853 Blood Glucose Abnormal 17 0.5 0.5 no signal
854 Myalgia 156 0.5 0.5 no signal
855 Rhinorrhoea 59 0.5 0.5 no signal
856 Osteonecrosis 30 0.5 0.5 no signal
857 Abdominal Distension 94 0.5 0.5 no signal
858 Hepatitis C 11 0.5 0.5 no signal
859 Pharyngeal Oedema 14 0.5 0.5 no signal
860 Hypertensive Crisis 10 0.5 0.5 no signal
861 Eye Discharge 9 0.5 0.5 no signal
862 Abscess 14 0.5 0.5 no signal
863 Viral Infection 29 0.5 0.5 no signal
864 Adverse Drug Reaction 78 0.5 0.5 no signal
865 Haematochezia 48 0.5 0.5 no signal
866 Iron Deficiency Anaemia 8 0.5 0.5 no signal
867 Visual Acuity Reduced 29 0.5 0.5 no signal
868 Transient Ischaemic Attack 29 0.5 0.5 no signal
869 Drug Ineffective 1,126 0.5 0.5 no signal
870 Splenomegaly 10 0.5 0.5 no signal
871 Abdominal Pain Upper 175 0.5 0.5 no signal
872 Cold Sweat 15 0.5 0.5 no signal
873 Leukaemia 8 0.5 0.5 no signal
874 Haematoma 22 0.5 0.5 no signal
875 Urinary Incontinence 25 0.5 0.5 no signal
876 Thirst 15 0.5 0.5 no signal
877 Delusion 13 0.5 0.5 no signal
878 Hypersomnia 24 0.5 0.5 no signal
879 Skin Haemorrhage 12 0.5 0.5 no signal
880 Faeces Discoloured 18 0.5 0.5 no signal
881 Dizziness 413 0.5 0.5 no signal
882 Impaired Healing 27 0.5 0.5 no signal
883 Gastrointestinal Pain 9 0.5 0.5 no signal
884 Balance Disorder 71 0.5 0.5 no signal
885 Loss Of Consciousness 105 0.5 0.5 no signal
886 Lethargy 47 0.5 0.5 no signal
887 Swelling Face 53 0.5 0.4 no signal
888 Laboratory Test Abnormal 24 0.5 0.4 no signal
889 Hallucination, Visual 17 0.4 0.4 no signal
890 Renal Injury 24 0.4 0.4 no signal
891 Brain Injury 8 0.4 0.4 no signal
892 Covid-19 141 0.4 0.4 no signal
893 Diabetes Mellitus Inadequate Control 14 0.4 0.4 no signal
894 Dry Mouth 64 0.4 0.4 no signal
895 Night Sweats 25 0.4 0.4 no signal
896 Blister 43 0.4 0.4 no signal
897 Bronchitis 57 0.4 0.4 no signal
898 Feeling Hot 47 0.4 0.4 no signal
899 Paraesthesia Oral 11 0.4 0.4 no signal
900 Brain Neoplasm 7 0.4 0.4 no signal
901 Dry Skin 100 0.4 0.4 no signal
902 Hypokinesia 11 0.4 0.4 no signal
903 Spinal Fracture 15 0.4 0.4 no signal
904 Breast Cancer Metastatic 8 0.4 0.4 no signal
905 Sputum Discoloured 7 0.4 0.4 no signal
906 Fracture 14 0.4 0.4 no signal
907 Intentional Product Use Issue 65 0.4 0.4 no signal
908 Drug Ineffective For Unapproved Indication 41 0.4 0.4 no signal
909 Dyspepsia 72 0.4 0.4 no signal
910 Autoimmune Disorder 7 0.4 0.4 no signal
911 Palpitations 85 0.4 0.4 no signal
912 Hyperhidrosis 93 0.4 0.4 no signal
913 Pelvic Pain 13 0.4 0.4 no signal
914 Movement Disorder 23 0.4 0.4 no signal
915 Fistula 8 0.4 0.4 no signal
916 Restlessness 26 0.4 0.4 no signal
917 Tuberculosis 9 0.4 0.4 no signal
918 Heart Rate Increased 69 0.4 0.4 no signal
919 Pallor 19 0.4 0.4 no signal
920 Coma 33 0.4 0.4 no signal
921 Urticaria 115 0.4 0.4 no signal
922 Cardiac Failure Congestive 56 0.4 0.4 no signal
923 Apathy 10 0.4 0.4 no signal
924 Post Procedural Haemorrhage 8 0.4 0.4 no signal
925 Hypoglycaemia 33 0.4 0.4 no signal
926 Neck Pain 38 0.4 0.4 no signal
927 Discomfort 41 0.4 0.4 no signal
928 Sopor 9 0.4 0.4 no signal
929 Fluid Retention 34 0.4 0.4 no signal
930 Gout 12 0.4 0.4 no signal
931 Throat Tightness 18 0.4 0.4 no signal
932 Arthralgia 276 0.4 0.4 no signal
933 Haemorrhoids 13 0.4 0.4 no signal
934 Somnolence 133 0.4 0.4 no signal
935 Hypoaesthesia 99 0.4 0.4 no signal
936 Pain 405 0.4 0.4 no signal
937 Colitis Ulcerative 29 0.4 0.4 no signal
938 Arthritis 51 0.4 0.4 no signal
939 Laryngitis 7 0.4 0.4 no signal
940 Ocular Hyperaemia 30 0.4 0.4 no signal
941 Pharyngitis 8 0.4 0.4 no signal
942 Grand Mal Convulsion 6 0.4 0.4 no signal
943 Rib Fracture 13 0.4 0.3 no signal
944 Infusion Site Pain 8 0.3 0.3 no signal
945 Gait Disturbance 120 0.3 0.3 no signal
946 Pollakiuria 26 0.3 0.3 no signal
947 Drug Effect Incomplete 23 0.3 0.3 no signal
948 Mydriasis 8 0.3 0.3 no signal
949 Sensory Disturbance 10 0.3 0.3 no signal
950 Peripheral Swelling 95 0.3 0.3 no signal
951 Vitreous Floaters 6 0.3 0.3 no signal
952 Dysstasia 18 0.3 0.3 no signal
953 Ill-defined Disorder 37 0.3 0.3 no signal
954 Eye Pruritus 20 0.3 0.3 no signal
955 Drug Level Increased 10 0.3 0.3 no signal
956 Bladder Disorder 6 0.3 0.3 no signal
957 Lip Swelling 20 0.3 0.3 no signal
958 Salivary Hypersecretion 6 0.3 0.3 no signal
959 Clostridium Difficile Infection 13 0.3 0.3 no signal
960 Headache 373 0.3 0.3 no signal
961 Eye Swelling 22 0.3 0.3 no signal
962 Type 2 Diabetes Mellitus 20 0.3 0.3 no signal
963 Incorrect Product Administration Duration 12 0.3 0.3 no signal
964 Dry Throat 6 0.3 0.3 no signal
965 Product Prescribing Issue 12 0.3 0.3 no signal
966 Photophobia 11 0.3 0.3 no signal
967 Hepatic Cirrhosis 11 0.3 0.3 no signal
968 Tooth Abscess 6 0.3 0.3 no signal
969 Gastrooesophageal Reflux Disease 47 0.3 0.3 no signal
970 Joint Swelling 70 0.3 0.3 no signal
971 Peripheral Coldness 8 0.3 0.3 no signal
972 Pain In Extremity 171 0.3 0.3 no signal
973 Localised Infection 14 0.3 0.3 no signal
974 Wound 16 0.3 0.3 no signal
975 Fall 190 0.3 0.3 no signal
976 Vision Blurred 78 0.3 0.3 no signal
977 Transfusion 6 0.3 0.3 no signal
978 Rheumatoid Arthritis 64 0.3 0.3 no signal
979 Blood Triglycerides Increased 10 0.3 0.3 no signal
980 Muscle Twitching 13 0.3 0.3 no signal
981 Paralysis 8 0.3 0.3 no signal
982 Speech Disorder 29 0.3 0.3 no signal
983 Wound Infection 6 0.3 0.3 no signal
984 Femur Fracture 17 0.3 0.3 no signal
985 Tooth Fracture 6 0.3 0.3 no signal
986 Dental Caries 6 0.3 0.3 no signal
987 Bedridden 7 0.3 0.3 no signal
988 Hospitalisation 81 0.3 0.3 no signal
989 Spinal Disorder 5 0.3 0.3 no signal
990 Hip Arthroplasty 8 0.3 0.3 no signal
991 Drug Hypersensitivity 101 0.3 0.3 no signal
992 Hair Texture Abnormal 7 0.3 0.3 no signal
993 Blood Glucose Increased 98 0.3 0.3 no signal
994 Vaginal Haemorrhage 22 0.3 0.3 no signal
995 Gait Inability 17 0.3 0.3 no signal
996 Drug Effective For Unapproved Indication 15 0.3 0.3 no signal
997 Cardiovascular Disorder 13 0.3 0.3 no signal
998 Sinus Disorder 10 0.3 0.3 no signal
999 Oral Discomfort 7 0.3 0.3 no signal
1000 Feeling Cold 14 0.3 0.3 no signal
1001 Cystitis 16 0.3 0.3 no signal
1002 Lactic Acidosis 16 0.3 0.3 no signal
1003 Blood Test Abnormal 7 0.3 0.3 no signal
1004 Gastroenteritis Viral 9 0.3 0.3 no signal
1005 Blindness Unilateral 7 0.3 0.3 no signal
1006 Blood Pressure Increased 76 0.3 0.3 no signal
1007 Joint Stiffness 13 0.3 0.3 no signal
1008 Swelling 46 0.3 0.3 no signal
1009 Ear Discomfort 5 0.3 0.3 no signal
1010 Sleep Disorder 34 0.3 0.3 no signal
1011 Secretion Discharge 6 0.3 0.3 no signal
1012 Euphoric Mood 5 0.3 0.3 no signal
1013 No Therapeutic Response 6 0.3 0.3 no signal
1014 Pemphigus 6 0.3 0.3 no signal
1015 Tooth Extraction 6 0.3 0.3 no signal
1016 Heart Rate Decreased 17 0.3 0.3 no signal
1017 Brain Fog 7 0.3 0.3 no signal
1018 Skin Fissures 9 0.3 0.3 no signal
1019 Full Blood Count Abnormal 5 0.3 0.3 no signal
1020 Depression 108 0.3 0.3 no signal
1021 Influenza 52 0.3 0.3 no signal
1022 Visual Impairment 57 0.3 0.3 no signal
1023 Oral Herpes 9 0.3 0.3 no signal
1024 Influenza Like Illness 38 0.3 0.3 no signal
1025 Blood Pressure Systolic Increased 9 0.3 0.3 no signal
1026 Blood Glucose Fluctuation 5 0.3 0.3 no signal
1027 Dry Eye 22 0.3 0.3 no signal
1028 Insomnia 121 0.3 0.2 no signal
1029 Bradycardia 24 0.2 0.2 no signal
1030 Red Blood Cell Sedimentation Rate Increased 5 0.2 0.2 no signal
1031 Agitation 33 0.2 0.2 no signal
1032 Malignant Melanoma 6 0.2 0.2 no signal
1033 Abasia 11 0.2 0.2 no signal
1034 Hot Flush 33 0.2 0.2 no signal
1035 Increased Tendency To Bruise 4 0.2 0.2 no signal
1036 Medication Error 24 0.2 0.2 no signal
1037 Aphonia 6 0.2 0.2 no signal
1038 Erectile Dysfunction 11 0.2 0.2 no signal
1039 Disturbance In Attention 23 0.2 0.2 no signal
1040 Psychomotor Hyperactivity 7 0.2 0.2 no signal
1041 Weight Increased 93 0.2 0.2 no signal
1042 Anxiety 119 0.2 0.2 no signal
1043 Respiratory Depression 5 0.2 0.2 no signal
1044 Psychotic Disorder 12 0.2 0.2 no signal
1045 Tremor 67 0.2 0.2 no signal
1046 Throat Irritation 18 0.2 0.2 no signal
1047 Injection Site Extravasation 5 0.2 0.2 no signal
1048 Eye Disorder 13 0.2 0.2 no signal
1049 Dementia 11 0.2 0.2 no signal
1050 Mobility Decreased 28 0.2 0.2 no signal
1051 Treatment Noncompliance 21 0.2 0.2 no signal
1052 Depressed Mood 20 0.2 0.2 no signal
1053 Eye Irritation 21 0.2 0.2 no signal
1054 Breast Pain 4 0.2 0.2 no signal
1055 Contusion 36 0.2 0.2 no signal
1056 Eye Haemorrhage 5 0.2 0.2 no signal
1057 Hallucination 28 0.2 0.2 no signal
1058 Nephrolithiasis 17 0.2 0.2 no signal
1059 Sinusitis 38 0.2 0.2 no signal
1060 Skin Burning Sensation 26 0.2 0.2 no signal
1061 Osteoarthritis 15 0.2 0.2 no signal
1062 Abdominal Discomfort 58 0.2 0.2 no signal
1063 Burning Sensation 24 0.2 0.2 no signal
1064 Tooth Loss 7 0.2 0.2 no signal
1065 Haemorrhage Intracranial 5 0.2 0.2 no signal
1066 Mood Altered 9 0.2 0.2 no signal
1067 Thyroid Cancer 4 0.2 0.2 no signal
1068 Abnormal Behaviour 13 0.2 0.2 no signal
1069 Arthropathy 18 0.2 0.2 no signal
1070 Lymphoma 5 0.2 0.2 no signal
1071 Personality Change 3 0.2 0.2 no signal
1072 Cardiac Disorder 30 0.2 0.2 no signal
1073 Increased Appetite 6 0.2 0.2 no signal
1074 Eye Inflammation 3 0.2 0.2 no signal
1075 Poisoning 4 0.2 0.2 no signal
1076 Eructation 6 0.2 0.2 no signal
1077 Parkinsonism 3 0.2 0.2 no signal
1078 Decreased Immune Responsiveness 3 0.2 0.2 no signal
1079 Sedation 8 0.2 0.2 no signal
1080 Activities Of Daily Living Impaired 6 0.2 0.2 no signal
1081 Helicobacter Infection 3 0.2 0.2 no signal
1082 Akathisia 4 0.2 0.2 no signal
1083 Amnesia 19 0.2 0.2 no signal
1084 Psoriasis 37 0.2 0.2 no signal
1085 Aggression 14 0.2 0.2 no signal
1086 Accidental Overdose 10 0.2 0.2 no signal
1087 Nasal Congestion 16 0.2 0.2 no signal
1088 Musculoskeletal Stiffness 23 0.1 0.1 no signal
1089 Sexual Dysfunction 3 0.1 0.1 no signal
1090 Nasopharyngitis 47 0.1 0.1 no signal
1091 Cataract 15 0.1 0.1 no signal
1092 Hallucination, Auditory 4 0.1 0.1 no signal
1093 Premature Delivery 4 0.1 0.1 no signal
1094 Inappropriate Schedule Of Drug Administration 18 0.1 0.1 no signal
1095 Feeling Abnormal 59 0.1 0.1 no signal
1096 Memory Impairment 33 0.1 0.1 no signal
1097 Hair Colour Changes 3 0.1 0.1 no signal
1098 Acne 17 0.1 0.1 no signal
1099 Underdose 16 0.1 0.1 no signal
1100 Muscle Spasms 40 0.1 0.1 no signal
1101 Circumstance Or Information Capable Of Leading To Medication Error 7 0.1 0.1 no signal
1102 Incorrect Dose Administered 46 0.1 0.1 no signal
1103 Meningioma 3 0.1 0.1 no signal
1104 Overdose 44 0.1 0.1 no signal
1105 Intentional Product Misuse 17 0.1 0.1 no signal
1106 Gynaecomastia 6 0.1 0.1 no signal
1107 Plasma Cell Myeloma 7 0.1 0.1 no signal
1108 Synovitis 3 0.1 0.1 no signal
1109 Asthma 18 0.1 0.1 no signal
1110 Extrapyramidal Disorder 4 0.1 0.1 no signal
1111 No Adverse Event 27 0.1 0.1 no signal
1112 Incorrect Drug Administration Duration 4 0.1 0.1 no signal
1113 Illness 14 0.1 0.1 no signal
1114 Bladder Cancer 8 0.1 0.1 no signal
1115 Oesophageal Carcinoma 4 0.1 0.1 no signal
1116 Emotional Distress 15 0.1 0.1 no signal
1117 Product Dose Omission Issue 29 0.1 0.1 no signal
1118 Accidental Exposure To Product 10 0.1 0.1 no signal
1119 Breast Cancer 9 0.1 0.1 no signal
1120 Dependence 5 0.0 0.0 no signal
1121 Wrong Technique In Product Usage Process 18 0.0 0.0 no signal
1122 Product Adhesion Issue 3 0.0 0.0 no signal
1123 Renal Cancer 4 0.0 0.0 no signal