Reaction

Febrile Bone Marrow Aplasia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,132 reports · 176 co-occurring drugs

As of the last recalculation, Febrile Bone Marrow Aplasia appears in 4,132 FAERS reports alongside 176 co-occurring drug terms. The strongest observed disproportionality signal is PEGASPARGASE (PRR 332.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pegaspargase	677	332.9	352.5
Cytarabine	732	74.4	75.3
Vincristine Sulfate	271	49.8	50.2
Pemetrexed Disodium	287	40.7	41.0
Fosaprepitant Dimeglumine	103	38.7	39.0
Pemetrexed	157	38.3	38.6
Anti-Itch	403	33.4	33.6
Anti-Pruritic	403	33.4	33.6
Antipruritic (Anti-Itch)	403	33.4	33.6
Cool Relief Gel With Aloe	403	33.4	33.6
Drs. Hydrocortisone	403	33.4	33.6
Hydrocortisone Continuous Spray	403	33.4	33.6
Hydrocortisone Spray	403	33.4	33.6
Anti-Itch Cream	403	33.4	33.6
Hydrocortisone Lotion	403	33.4	33.6
Hydrocortisone Cream 1%	403	33.4	33.6
Hydrocortisone Cream 1/2%	403	33.4	33.6
Hydrocortisone 1%	403	33.4	33.6
Sulfamethoxazole And Trimethoprim	493	33.3	33.5
Hydrocortisone Cream	403	33.3	33.5
Brentuximab Vedotin	66	32.9	33.2
Aprepitant	115	32.2	32.4
Mesna Injection	52	32.1	32.3
Ifosfamide	131	31.7	31.9
Mesna	52	31.5	31.7
Hydrocortisone Acetate	406	31.1	31.3
Cyclophosphamide Injection, Solution	856	30.5	30.6
Cyclophosphamide	856	30.5	30.6
Cyclophosphamide For Injection	856	30.5	30.6
Mercaptopurine	96	28.5	28.7
Etoposide	366	27.4	27.5
Hydrocortisone	408	25.4	25.6
Doxorubicin	403	25.1	25.2
Doxorubicin Hydrochloride	138	22.0	22.1
Carboplatin	485	21.7	21.7
Methylprednisolone Acetate	34	21.6	21.6
Valacyclovir	158	19.8	19.9
Bleomycin Sulfate	39	19.2	19.3
Azacitidine	97	16.8	16.9
Atovaquone	25	15.7	15.8
Azacitidine For	55	15.4	15.5
Filgrastim	112	15.4	15.4
Melphalan	67	15.1	15.1
Piperacillin Sodium,Tazobactam Sodium	76	14.7	14.7
Melphalan Hydrochloride	71	14.5	14.5
Dexamethasone 1.5 Mg	708	14.5	14.5
Dexamethasone	708	14.3	14.3
Axicabtagene Ciloleucel	27	13.9	13.9
Cisplatin	201	13.6	13.6
Methotrexate	879	13.1	13.1
Methotrexate Sodium	944	12.4	12.4
Amikacin	41	12.2	12.2
Leucovorin Calcium	44	11.7	11.7
Valacyclovir Hydrochloride	158	11.7	11.7
Pembrolizumab	228	11.5	11.5
Posaconazole	36	11.2	11.3
Thiotepa	21	11.1	11.2
Micafungin Sodium	18	10.7	10.8
Esomeprazole	126	10.5	10.5
Ondansetron	210	10.1	10.2
Ondansetron Tablets	210	10.1	10.2
Ondansetron Hydrochloride	229	9.9	9.9
Fluorouracil Cream, 0.5%	143	9.7	9.8
Fluorouracil	143	9.6	9.6
Methylprednisolone Sodium Succinate	86	9.5	9.5
Piperacillin And Tazobactam	24	9.5	9.5
Sodium Bicarbonate	41	9.0	9.0
Sodium Bicarbonate Injection,	41	9.0	9.0
Fludarabine Phosphate	68	8.8	8.9
Paclitaxel (Aibumin-Bound)	137	8.6	8.7
Rituximab	333	8.5	8.6
Cetuximab	52	8.5	8.5
Bendamustine Hydrochloride	20	8.4	8.5
Erythropoietin	34	8.4	8.4
Nebivolol	26	8.3	8.3
Busulfan	25	8.0	8.1
Vancomycin	90	8.0	8.0
Phytonadione	13	7.7	7.8
Obinutuzumab	25	7.7	7.7
Vancomycin Hydrochloride	98	7.6	7.7
Paclitaxel	144	7.6	7.6
Valganciclovir Hydrochloride Powder,	18	7.5	7.5
Gentamicin	19	7.3	7.4
Venetoclax	88	7.3	7.3
Carboxymethylcellulose Sodium	13	7.0	7.0
Amphotericin B	17	6.9	6.9
Panitumumab	21	6.8	6.8
Methylprednisolone	177	6.7	6.7
Daptomycin	12	6.6	6.6
Ceftriaxone Sodium	49	6.5	6.5
Dexamethasone Sodium Phosphate	13	6.5	6.5
Valganciclovir	24	6.4	6.5
Valganciclovir Hydrochloride	24	6.4	6.5
Posaconazole Delayed-Release	14	6.4	6.4
Trimethoprim	15	6.4	6.4
Gentamicin Sulfate	20	6.4	6.4
Pegfilgrastim	122	6.4	6.4
Oxazepam	27	6.4	6.4
Gemcitabine Hydrochloride	66	6.4	6.4
Meropenem	40	6.3	6.3
Enoxaparin Sodium	71	6.3	6.3
Carfilzomib	35	6.3	6.3
Piperacillin Sodium And Tazobactam Sodium	24	6.2	6.2
Ceftriaxone	40	6.2	6.2
Dimenhydrinate	13	6.2	6.2
Bortezomib	104	6.0	6.0
Gemcitabine	45	5.8	5.8
Docetaxel Anhydrous	76	5.8	5.8
Alemtuzumab	22	5.8	5.8
Daratumumab	45	5.7	5.7
Docetaxel	75	5.7	5.7
Darbepoetin Alfa	60	5.7	5.7
Amoxicillin And Clavulanate Potassium	30	5.6	5.6
Durvalumab	22	5.5	5.5
Ciprofolxacin	76	5.4	5.4
Ciprofloxacin Tablets	76	5.4	5.4
Atezolizumab	41	5.4	5.4
Voriconazole	32	5.3	5.3
Cladribine	10	5.3	5.3
Bendamustine Hcl	16	5.2	5.2
Bevacizumab	124	5.2	5.2
Febuxostat Tablets 40 Mg	10	5.0	5.0
Febuxostat Tablets 80 Mg	10	5.0	5.0
Loperamide Hydrochloride Oral	10	4.9	4.9
Granisetron Hydrochloride	10	4.8	4.8
Granisetron	10	4.8	4.8
Polyethylene Glycol	10	4.7	4.7
Instalax Polyethylene Glycol 3350	11	4.5	4.5
Midazolam	22	4.4	4.4
Polyethylene Glycol 400	11	4.4	4.4
Lactulose	33	4.4	4.4
Midazolam Hydrochloride	23	4.3	4.3
Irinotecan Hydrochloride	11	4.3	4.3
Temozolomide	18	4.3	4.3
Ciprofloxacin	76	4.2	4.2
Ciprofloxacin Hydrochloride	80	4.2	4.2
Nebivolol Hydrochloride	28	4.2	4.2
Bisoprolol Fumarate	108	4.1	4.1
Oxaliplatin	59	4.0	4.1
Darunavir	12	4.0	4.0
Hydroxyzine	37	3.9	3.9
Loperamide Hcl	10	3.9	3.9
Prednisolone	135	3.9	3.9
Prednisolone Oral	135	3.9	3.9
Prednisolone Oral Solution	135	3.9	3.9
Hydroxyurea	16	3.8	3.8
Tobramycin Solution	9	3.8	3.8
Imatinib	13	3.7	3.7
Iron Sucrose	7	3.7	3.7
Tobramycin Sulfate	9	3.7	3.7
Cenobamate	6	3.6	3.6
Amoxicillin	53	3.5	3.5
Ixazomib	20	3.5	3.5
Esomeprazole Magnesium	154	3.4	3.4
Trastuzumab	46	3.4	3.4
Pertuzumab	18	3.3	3.3
Metoclopramide	36	3.3	3.3
Ritonavir	19	3.3	3.3
Letrozole Tablets	30	3.2	3.2
Allopurinol	96	3.1	3.1
Fondaparinux Sodium	5	3.1	3.1
Febuxostat	10	3.0	3.0
Acyclovir	65	2.9	2.9
Voriconazole Injection	12	2.8	2.8
Thalidomide	20	2.8	2.8
Nilotinib	14	2.4	2.4
Capecitabine	41	2.3	2.3
Deferasirox	11	2.1	2.1
Encorafenib	4	2.0	2.0
Fam-Trastuzumab Deruxtecan-Nxki	4	2.0	2.0
Pomalidomide	35	1.7	1.7
Dasatinib	12	1.6	1.6
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	1.4	1.4
Apalutamide	3	1.3	1.3
Lenalidomide	102	1.2	1.2
Dulaglutide	18	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.