OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Selexipag

1,128 flagged reaction(s) · 145,959 total co-reports · max PRR 217.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Right Atrial Pressure Increased 17 217.1 217.3 signal
2 Cardiothoracic Ratio Increased 11 170.2 170.3 signal
3 Intracardiac Pressure Increased 13 143.3 143.4 signal
4 Atrial Septal Defect Repair 23 126.8 126.9 signal
5 Cardiac Output Increased 23 126.8 126.9 signal
6 Pulmonary Arterial Wedge Pressure Increased 22 120.4 120.5 signal
7 Walking Distance Test Abnormal 49 118.8 119.0 signal
8 Bendopnoea 26 116.9 117.0 signal
9 Pulmonary Veno-occlusive Disease 84 112.1 112.5 signal
10 Pulmonary Arterial Pressure Increased 194 109.9 110.8 signal
11 Pulmonary Arterial Hypertension 1,703 108.1 115.7 signal
12 Ventilation Perfusion Mismatch 31 103.1 103.2 signal
13 Right-to-left Cardiac Shunt 25 102.1 102.2 signal
14 Transplant Evaluation 56 100.6 100.8 signal
15 Pulmonary Hypertensive Crisis 26 88.3 88.4 signal
16 Oxygen Consumption Increased 230 88.1 88.9 signal
17 Right Ventricular Enlargement 30 85.6 85.7 signal
18 Pulmonary Arterial Pressure Abnormal 27 84.5 84.6 signal
19 Cardiac Failure High Output 21 79.0 79.0 signal
20 Pain In Jaw 2,434 76.7 84.6 signal
21 Right Ventricular Failure 601 75.9 77.7 signal
22 Catheterisation Cardiac Abnormal 22 72.5 72.6 signal
23 Pulmonary Endarterectomy 12 72.1 72.1 signal
24 Endarterectomy 17 66.4 66.4 signal
25 Paracentesis 42 59.5 59.6 signal
26 Mineral Supplementation 29 56.9 57.0 signal
27 Brain Natriuretic Peptide Abnormal 14 56.6 56.6 signal
28 Crest Syndrome 15 54.9 54.9 signal
29 Right Ventricular Dilatation 36 54.8 54.8 signal
30 Catheter Management 55 52.9 53.0 signal
31 Pulmonary Artery Dilatation 21 52.6 52.7 signal
32 Brain Natriuretic Peptide Increased 181 50.9 51.3 signal
33 Right Ventricular Systolic Pressure Increased 18 49.6 49.6 signal
34 Oxygen Therapy 93 49.4 49.6 signal
35 Systemic Scleroderma 41 49.3 49.4 signal
36 Abdominal Cavity Drainage 24 49.0 49.1 signal
37 Pericardial Drainage 13 46.7 46.7 signal
38 N-terminal Prohormone Brain Natriuretic Peptide Increased 73 44.8 44.9 signal
39 Catheterisation Cardiac 231 44.8 45.2 signal
40 Catheter Site Irritation 16 43.1 43.1 signal
41 Catheter Site Rash 21 39.9 39.9 signal
42 Device Maintenance Issue 26 39.4 39.4 signal
43 Pulmonary Hypertension 905 36.9 38.2 signal
44 Scleroderma 156 36.5 36.7 signal
45 Dyspnoea At Rest 121 35.6 35.7 signal
46 Dependence On Oxygen Therapy 19 33.6 33.6 signal
47 Metapneumovirus Infection 30 33.6 33.6 signal
48 Catheter Site Pruritus 34 33.0 33.0 signal
49 Biopsy Liver 16 32.8 32.8 signal
50 Right Ventricular Dysfunction 41 32.3 32.3 signal
51 Congestive Hepatopathy 16 30.4 30.5 signal
52 Biopsy Lung 13 29.6 29.6 signal
53 Catheter Removal 12 28.5 28.5 signal
54 Catheter Site Discharge 37 28.4 28.4 signal
55 Therapy Change 324 28.4 28.7 signal
56 Diet Noncompliance 12 27.8 27.8 signal
57 Dyspnoea Exertional 1,229 27.6 29.0 signal
58 Dizziness Exertional 24 27.2 27.2 signal
59 Infusion Site Warmth 38 26.6 26.6 signal
60 Transfusion 329 26.3 26.7 signal
61 Infusion Site Inflammation 21 26.2 26.2 signal
62 Cardioversion 43 25.7 25.8 signal
63 Infusion Site Discharge 51 25.1 25.1 signal
64 Infusion Site Pain 375 24.7 25.0 signal
65 Haemorrhoid Operation 13 24.4 24.4 signal
66 Catheter Site Pain 73 24.1 24.2 signal
67 Infusion Site Vesicles 15 24.1 24.1 signal
68 Concomitant Disease Aggravated 176 23.9 24.1 signal
69 Sickle Cell Disease 13 23.7 23.7 signal
70 Lung Transplant 100 23.5 23.6 signal
71 Gastric Varices 13 23.5 23.5 signal
72 Chronic Hepatic Failure 18 23.1 23.2 signal
73 Catheter Site Erythema 57 22.8 22.9 signal
74 Nocturnal Dyspnoea 34 22.4 22.4 signal
75 Infusion Site Infection 60 22.2 22.2 signal
76 Left Ventricular Failure 90 22.1 22.2 signal
77 Catheter Placement 49 22.0 22.1 signal
78 Infusion Site Induration 37 21.8 21.8 signal
79 Fluid Retention 1,321 21.8 22.9 signal
80 Primary Biliary Cholangitis 12 21.7 21.8 signal
81 Infusion Site Irritation 32 21.5 21.6 signal
82 Hypervolaemia 123 21.5 21.6 signal
83 Right Atrial Dilatation 13 21.3 21.3 signal
84 Packed Red Blood Cell Transfusion 34 21.2 21.2 signal
85 Faeces Soft 171 19.7 19.9 signal
86 Fluid Overload 336 19.0 19.2 signal
87 Vascular Device Infection 102 18.8 18.9 signal
88 Polypectomy 18 18.7 18.7 signal
89 Upper Respiratory Tract Inflammation 27 18.7 18.7 signal
90 Cardiac Ablation 39 18.4 18.4 signal
91 Infusion Site Swelling 135 18.3 18.4 signal
92 Infusion Site Erythema 180 18.1 18.2 signal
93 Cardiorenal Syndrome 12 17.5 17.5 signal
94 Jugular Vein Distension 12 17.4 17.4 signal
95 Infusion Site Discolouration 18 17.4 17.4 signal
96 Systolic Dysfunction 22 17.4 17.4 signal
97 Aspiration Pleural Cavity 16 17.2 17.2 signal
98 Infusion Site Rash 27 16.5 16.5 signal
99 Cor Pulmonale 19 16.4 16.4 signal
100 Oxygen Saturation Abnormal 55 16.3 16.4 signal
101 Infusion Site Pruritus 61 16.3 16.3 signal
102 Infusion Site Discomfort 20 16.3 16.3 signal
103 Oxygen Saturation Decreased 1,069 15.9 16.6 signal
104 Dyspnoea Paroxysmal Nocturnal 14 15.8 15.8 signal
105 Atrial Tachycardia 38 15.0 15.0 signal
106 Drug Titration Error 46 14.8 14.8 signal
107 Infusion Site Haemorrhage 57 14.6 14.6 signal
108 Right Ventricular Hypertrophy 16 14.6 14.6 signal
109 Arteriovenous Malformation 15 13.6 13.6 signal
110 Catheter Site Swelling 15 13.5 13.5 signal
111 Localised Oedema 75 13.4 13.5 signal
112 Cardiac Output Decreased 14 13.2 13.2 signal
113 Intra-abdominal Fluid Collection 28 13.1 13.1 signal
114 Dysentery 27 12.0 12.1 signal
115 Central Venous Catheterisation 44 12.0 12.1 signal
116 Pulmonary Pain 41 11.8 11.8 signal
117 Concomitant Disease Progression 28 11.7 11.7 signal
118 Catheter Site Infection 53 11.7 11.7 signal
119 Blood Pressure Systolic Decreased 64 11.7 11.7 signal
120 Infusion Site Reaction 41 11.7 11.7 signal
121 Lower Respiratory Tract Congestion 24 11.7 11.7 signal
122 Tracheostomy 20 11.6 11.6 signal
123 Vasodilatation 35 11.5 11.5 signal
124 Disease Complication 63 11.3 11.4 signal
125 Portal Hypertension 42 11.2 11.3 signal
126 Pericardial Effusion 313 11.2 11.4 signal
127 Heart Transplant 12 11.0 11.0 signal
128 Marasmus 20 11.0 11.0 signal
129 Dizziness Postural 126 10.8 10.9 signal
130 Iron Deficiency Anaemia 119 10.7 10.7 signal
131 Intensive Care 18 10.7 10.7 signal
132 Oedema 693 10.6 10.8 signal
133 Telangiectasia 12 10.4 10.4 signal
134 Chronic Respiratory Failure 15 10.4 10.4 signal
135 Hypoxia 440 10.4 10.5 signal
136 Orthopnoea 40 10.3 10.4 signal
137 Liver Transplant 45 10.3 10.3 signal
138 Exercise Tolerance Decreased 69 10.0 10.0 signal
139 Wrong Dose 29 9.9 9.9 signal
140 Carbon Dioxide Increased 16 9.7 9.7 signal
141 Myocardial Necrosis Marker Increased 19 9.7 9.7 signal
142 Myalgia 1,981 9.6 10.3 signal
143 Ear Congestion 31 9.5 9.5 signal
144 Endotracheal Intubation 32 9.4 9.4 signal
145 Device Infusion Issue 28 9.4 9.4 signal
146 Angioplasty 17 9.4 9.4 signal
147 Flushing 1,147 9.3 9.6 signal
148 Nasal Congestion 646 9.1 9.3 signal
149 Headache 6,740 8.9 11.7 signal
150 Echocardiogram Abnormal 15 8.9 8.9 signal
151 Pulse Abnormal 26 8.9 8.9 signal
152 Catheter Site Haemorrhage 26 8.7 8.7 signal
153 Carbon Dioxide Decreased 12 8.7 8.7 signal
154 Ascites 307 8.6 8.7 signal
155 Rehabilitation Therapy 40 8.5 8.6 signal
156 Heart Valve Replacement 15 8.4 8.4 signal
157 Hospice Care 100 8.4 8.4 signal
158 Pulmonary Congestion 134 8.3 8.4 signal
159 Paranasal Sinus Discomfort 38 8.3 8.3 signal
160 Atrial Flutter 80 8.2 8.2 signal
161 Cardiac Failure Acute 66 8.2 8.2 signal
162 Dialysis 141 8.2 8.2 signal
163 Cardiac Failure 788 8.1 8.3 signal
164 Haemoglobin Increased 43 7.9 7.9 signal
165 Walking Disability 20 7.9 7.9 signal
166 Dermatitis Contact 108 7.8 7.9 signal
167 Hospitalisation 1,449 7.8 8.2 signal
168 Emergency Care 28 7.8 7.8 signal
169 Pulmonary Oedema 421 7.7 7.8 signal
170 Mechanical Ventilation 18 7.7 7.7 signal
171 Therapy Non-responder 417 7.7 7.8 signal
172 Nasal Obstruction 17 7.6 7.6 signal
173 Seasonal Allergy 128 7.5 7.5 signal
174 Cardiac Discomfort 18 7.4 7.4 signal
175 Lung Opacity 23 7.3 7.4 signal
176 Device Alarm Issue 16 7.3 7.3 signal
177 Transplant 21 7.3 7.3 signal
178 Enteritis Infectious 15 7.2 7.3 signal
179 Syncope 877 7.2 7.4 signal
180 Acute Respiratory Failure 167 7.2 7.2 signal
181 Middle Ear Effusion 19 7.1 7.1 signal
182 Hypotension 1,726 7.1 7.5 signal
183 Iron Deficiency 38 7.0 7.0 signal
184 Medical Procedure 14 7.0 7.0 signal
185 Haemorrhoidal Haemorrhage 42 7.0 7.0 signal
186 Oedema Peripheral 1,041 7.0 7.3 signal
187 Device Related Infection 131 7.0 7.0 signal
188 Respiration Abnormal 58 7.0 7.0 signal
189 Dyspnoea 4,774 6.9 8.3 signal
190 Connective Tissue Disorder 12 6.9 6.9 signal
191 Mitral Valve Prolapse 14 6.9 6.9 signal
192 Hepatic Cirrhosis 155 6.8 6.9 signal
193 Haemoptysis 231 6.8 6.8 signal
194 Cardiac Failure Chronic 35 6.8 6.8 signal
195 Cardiac Pacemaker Insertion 49 6.7 6.8 signal
196 Blood Loss Anaemia 18 6.6 6.6 signal
197 Diarrhoea 5,173 6.6 8.0 signal
198 Facial Pain 71 6.5 6.6 signal
199 Decreased Activity 85 6.5 6.5 signal
200 Presyncope 188 6.4 6.4 signal
201 Hernia Repair 20 6.4 6.4 signal
202 Hypercapnia 23 6.3 6.3 signal
203 Injection Site Infection 25 6.3 6.3 signal
204 Gout 137 6.3 6.3 signal
205 Physical Deconditioning 19 6.2 6.2 signal
206 Heart Rate Abnormal 42 6.2 6.2 signal
207 Trismus 39 6.2 6.2 signal
208 Blood Iron Decreased 88 6.1 6.1 signal
209 Cardiomegaly 92 6.1 6.1 signal
210 Sinus Congestion 99 6.0 6.0 signal
211 Bedridden 96 6.0 6.0 signal
212 Productive Cough 344 6.0 6.0 signal
213 Peripheral Swelling 1,114 6.0 6.2 signal
214 Pain In Extremity 2,129 5.9 6.4 signal
215 Pulseless Electrical Activity 30 5.9 5.9 signal
216 Nasal Dryness 45 5.9 5.9 signal
217 Blood Potassium Abnormal 19 5.9 5.9 signal
218 Epistaxis 535 5.9 6.0 signal
219 Rales 41 5.8 5.8 signal
220 Infusion Site Bruising 15 5.8 5.8 signal
221 Urine Output Decreased 61 5.7 5.7 signal
222 Pneumonia Viral 22 5.7 5.7 signal
223 Device Related Sepsis 14 5.7 5.7 signal
224 Neck Pain 385 5.6 5.7 signal
225 Terminal State 46 5.6 5.6 signal
226 Unevaluable Event 515 5.6 5.7 signal
227 Gastrointestinal Tube Insertion 17 5.6 5.6 signal
228 Head Discomfort 119 5.5 5.6 signal
229 Internal Haemorrhage 77 5.5 5.5 signal
230 Weight Fluctuation 70 5.5 5.5 signal
231 Blood Pressure Decreased 444 5.5 5.6 signal
232 Sinus Pain 15 5.3 5.3 signal
233 Cardiac Flutter 42 5.3 5.3 signal
234 Idiopathic Pulmonary Fibrosis 25 5.3 5.3 signal
235 Rhinovirus Infection 24 5.2 5.2 signal
236 Multiple Allergies 49 5.1 5.1 signal
237 Blood Uric Acid Increased 36 5.1 5.1 signal
238 Cardiac Operation 53 5.1 5.1 signal
239 Blood Potassium Decreased 187 5.1 5.1 signal
240 Aortic Valve Stenosis 11 5.0 5.0 signal
241 Decreased Appetite 1,412 5.0 5.2 signal
242 Drug Tolerance Decreased 17 5.0 5.0 signal
243 Ear Discomfort 62 5.0 5.0 signal
244 Pneumonia Bacterial 55 4.9 4.9 signal
245 Cardiac Dysfunction 22 4.9 4.9 signal
246 Paranasal Sinus Hypersecretion 23 4.9 4.9 signal
247 Abdominal Discomfort 999 4.9 5.1 signal
248 Non-cardiac Chest Pain 19 4.9 4.9 signal
249 Temporomandibular Joint Syndrome 16 4.8 4.8 signal
250 Colonoscopy 13 4.8 4.8 signal
251 Ammonia Increased 30 4.8 4.8 signal
252 Upper-airway Cough Syndrome 48 4.8 4.8 signal
253 Blood Pressure Abnormal 116 4.8 4.8 signal
254 Device Connection Issue 12 4.8 4.8 signal
255 Weight Abnormal 14 4.8 4.8 signal
256 Anal Incontinence 52 4.8 4.8 signal
257 Cyanosis 92 4.8 4.8 signal
258 Food Poisoning 31 4.8 4.8 signal
259 Restless Legs Syndrome 106 4.8 4.8 signal
260 Pleural Effusion 354 4.8 4.8 signal
261 Listless 19 4.7 4.7 signal
262 Respiratory Syncytial Virus Infection 50 4.7 4.7 signal
263 Functional Gastrointestinal Disorder 20 4.7 4.7 signal
264 Therapeutic Product Effect Variable 22 4.7 4.7 signal
265 Aortic Stenosis 20 4.7 4.7 signal
266 Stent Placement 46 4.7 4.7 signal
267 Creatinine Renal Clearance Decreased 23 4.7 4.7 signal
268 Sudden Death 61 4.7 4.7 signal
269 Eye Contusion 12 4.7 4.7 signal
270 Chest Pain 1,056 4.7 4.8 signal
271 Breath Sounds Abnormal 28 4.7 4.7 signal
272 Chemotherapy 21 4.6 4.7 signal
273 Product Administered To Patient Of Inappropriate Age 34 4.6 4.6 signal
274 Palpitations 662 4.6 4.7 signal
275 Polyuria 46 4.6 4.6 signal
276 Purulent Discharge 24 4.6 4.6 signal
277 Pneumonia 1,813 4.6 4.9 signal
278 Generalised Oedema 68 4.5 4.5 signal
279 Lung Disorder 270 4.5 4.6 signal
280 Muscle Fatigue 23 4.5 4.5 signal
281 Intra-abdominal Haemorrhage 13 4.5 4.5 signal
282 Dyspepsia 531 4.4 4.5 signal
283 Respiratory Failure 392 4.4 4.5 signal
284 Abdominal Distension 558 4.4 4.5 signal
285 Brain Operation 12 4.4 4.4 signal
286 Chest Discomfort 542 4.4 4.4 signal
287 Sputum Discoloured 50 4.3 4.3 signal
288 Limb Discomfort 163 4.3 4.3 signal
289 Face Injury 20 4.3 4.3 signal
290 Device Power Source Issue 15 4.3 4.3 signal
291 Viral Upper Respiratory Tract Infection 25 4.3 4.3 signal
292 Nausea 4,103 4.3 4.9 signal
293 Toothache 94 4.3 4.3 signal
294 Abdominal Rigidity 14 4.2 4.3 signal
295 Product Dose Omission 343 4.2 4.3 signal
296 Respiratory Tract Infection Viral 12 4.2 4.2 signal
297 Oral Surgery 12 4.2 4.2 signal
298 Upper Respiratory Tract Congestion 15 4.2 4.2 signal
299 Supraventricular Tachycardia 49 4.2 4.2 signal
300 Cardiopulmonary Failure 20 4.2 4.2 signal
301 Migraine 484 4.2 4.2 signal
302 Gastroenteritis Viral 92 4.2 4.2 signal
303 Musculoskeletal Pain 266 4.1 4.2 signal
304 Peripheral Venous Disease 20 4.1 4.1 signal
305 Sinus Disorder 99 4.1 4.1 signal
306 Tricuspid Valve Incompetence 39 4.0 4.0 signal
307 Oropharyngeal Discomfort 44 4.0 4.0 signal
308 Hypopnoea 17 4.0 4.0 signal
309 Large Intestine Polyp 34 4.0 4.0 signal
310 Cataract Operation 29 4.0 4.0 signal
311 Heart Valve Incompetence 14 4.0 4.0 signal
312 Suffocation Feeling 12 4.0 4.0 signal
313 Frequent Bowel Movements 130 4.0 4.0 signal
314 Haemodynamic Instability 36 3.9 3.9 signal
315 Poor Quality Sleep 102 3.9 3.9 signal
316 Retching 101 3.9 3.9 signal
317 Blood Pressure Diastolic Decreased 35 3.9 3.9 signal
318 Pulmonary Alveolar Haemorrhage 26 3.8 3.8 signal
319 Heart Rate Increased 459 3.8 3.8 signal
320 Dizziness 2,304 3.8 4.1 signal
321 Appetite Disorder 30 3.8 3.8 signal
322 Ear Pain 88 3.7 3.7 signal
323 Faeces Discoloured 98 3.7 3.7 signal
324 Troponin Increased 34 3.7 3.7 signal
325 Haemoglobin Decreased 461 3.7 3.7 signal
326 Mucous Stools 22 3.7 3.7 signal
327 Cough 1,248 3.7 3.8 signal
328 Haematocrit Decreased 89 3.7 3.7 signal
329 Cardiac Failure Congestive 361 3.6 3.7 signal
330 Blood Urea Increased 74 3.6 3.6 signal
331 Atypical Pneumonia 13 3.6 3.6 signal
332 Gastrooesophageal Reflux Disease 348 3.6 3.6 signal
333 Gastrointestinal Motility Disorder 23 3.6 3.6 signal
334 Sluggishness 44 3.5 3.6 signal
335 Crepitations 13 3.5 3.5 signal
336 Localised Infection 104 3.5 3.5 signal
337 Secretion Discharge 53 3.5 3.5 signal
338 Respiratory Tract Congestion 68 3.5 3.5 signal
339 Gastric Disorder 148 3.5 3.5 signal
340 Thyroid Mass 16 3.5 3.5 signal
341 Sensitivity To Weather Change 22 3.4 3.4 signal
342 Coronavirus Infection 28 3.4 3.4 signal
343 Abdominal Pain Upper 861 3.4 3.5 signal
344 Swelling 391 3.4 3.5 signal
345 Sinus Headache 25 3.4 3.4 signal
346 Vomiting 1,953 3.4 3.6 signal
347 Atrial Septal Defect 35 3.4 3.4 signal
348 Gastric Haemorrhage 48 3.4 3.4 signal
349 Drug Intolerance 398 3.4 3.4 signal
350 Clostridium Difficile Infection 89 3.4 3.4 signal
351 Malaise 1,802 3.4 3.5 signal
352 Atrial Fibrillation 399 3.3 3.4 signal
353 Feeling Cold 114 3.3 3.4 signal
354 Hyperthyroidism 59 3.3 3.3 signal
355 Thyroiditis 12 3.3 3.3 signal
356 Sarcoidosis 19 3.3 3.3 signal
357 Interstitial Lung Disease 193 3.3 3.3 signal
358 Anaemia 761 3.3 3.3 signal
359 Pneumothorax 63 3.3 3.3 signal
360 Renal Disorder 185 3.2 3.3 signal
361 Arthralgia 1,637 3.2 3.4 signal
362 Condition Aggravated 1,189 3.2 3.3 signal
363 Nasopharyngitis 727 3.2 3.3 signal
364 Loss Of Consciousness 504 3.2 3.3 signal
365 Otitis Media 13 3.2 3.2 signal
366 Back Pain 908 3.2 3.3 signal
367 Heavy Menstrual Bleeding 31 3.2 3.2 signal
368 Respiratory Tract Infection 100 3.2 3.2 signal
369 Pulmonary Thrombosis 42 3.1 3.2 signal
370 Product Administration Interrupted 29 3.1 3.1 signal
371 Musculoskeletal Discomfort 65 3.1 3.1 signal
372 Bronchitis 281 3.1 3.1 signal
373 Weight Decreased 1,052 3.1 3.2 signal
374 Head Injury 119 3.1 3.1 signal
375 Ligament Sprain 37 3.1 3.1 signal
376 Rhinorrhoea 240 3.0 3.1 signal
377 Chronic Obstructive Pulmonary Disease 193 3.0 3.0 signal
378 Mouth Haemorrhage 27 3.0 3.0 signal
379 Musculoskeletal Chest Pain 57 3.0 3.0 signal
380 Sciatica 58 3.0 3.0 signal
381 Haematochezia 201 3.0 3.0 signal
382 Choking Sensation 20 3.0 3.0 signal
383 Gastrointestinal Disorder 321 3.0 3.0 signal
384 Feeling Abnormal 873 3.0 3.0 signal
385 Jaw Disorder 20 3.0 3.0 signal
386 Pain 2,218 3.0 3.1 signal
387 Flatulence 204 2.9 3.0 signal
388 Pulmonary Haemorrhage 28 2.9 2.9 signal
389 Influenza 400 2.9 3.0 signal
390 Gastroenteritis 52 2.9 2.9 signal
391 Complication Associated With Device 47 2.9 2.9 signal
392 Taste Disorder 71 2.9 2.9 signal
393 Product Supply Issue 25 2.9 2.9 signal
394 Bowel Movement Irregularity 27 2.9 2.9 signal
395 Pleurisy 21 2.9 2.9 signal
396 Upper Respiratory Tract Infection 162 2.9 2.9 signal
397 Bone Pain 205 2.9 2.9 signal
398 Cervical Vertebral Fracture 12 2.9 2.9 signal
399 Renal Function Test Abnormal 16 2.9 2.9 signal
400 Cellulitis 175 2.8 2.9 signal
401 Micturition Disorder 12 2.8 2.8 signal
402 Muscle Tightness 56 2.8 2.8 signal
403 Compression Fracture 18 2.8 2.8 signal
404 Blood Sodium Decreased 65 2.8 2.8 signal
405 International Normalised Ratio Abnormal 12 2.8 2.8 signal
406 Atelectasis 33 2.8 2.8 signal
407 Disease Progression 401 2.8 2.8 signal
408 Throat Irritation 152 2.8 2.8 signal
409 Viral Infection 113 2.8 2.8 signal
410 Ulcer Haemorrhage 23 2.8 2.8 signal
411 Rhinitis Allergic 15 2.8 2.8 signal
412 Photophobia 63 2.8 2.8 signal
413 Intentional Dose Omission 92 2.8 2.8 signal
414 Hysterectomy 29 2.7 2.8 signal
415 Blood Magnesium Decreased 29 2.7 2.8 signal
416 Haemorrhagic Diathesis 12 2.7 2.7 signal
417 Hypersomnia 96 2.7 2.7 signal
418 Fatigue 2,601 2.7 2.9 signal
419 Injection Site Discharge 17 2.7 2.7 signal
420 Skin Laceration 36 2.7 2.7 signal
421 Device Occlusion 46 2.7 2.7 signal
422 Renal Impairment 275 2.7 2.7 signal
423 Peripheral Coldness 45 2.7 2.7 signal
424 Rib Fracture 67 2.7 2.7 signal
425 Cardiac Disorder 305 2.7 2.7 signal
426 Tearfulness 14 2.6 2.7 signal
427 Bacteraemia 38 2.6 2.6 signal
428 Oliguria 20 2.6 2.6 signal
429 Diabetic Neuropathy 16 2.6 2.6 signal
430 Tooth Extraction 40 2.6 2.6 signal
431 Flank Pain 30 2.6 2.6 signal
432 Heart Rate Decreased 113 2.6 2.6 signal
433 Hip Surgery 17 2.6 2.6 signal
434 Kidney Infection 62 2.6 2.6 signal
435 Muscle Spasms 578 2.6 2.6 signal
436 Extrasystoles 22 2.6 2.6 signal
437 Electrolyte Imbalance 36 2.6 2.6 signal
438 Adverse Event 288 2.6 2.6 signal
439 Blood Count Abnormal 48 2.6 2.6 signal
440 Hot Flush 235 2.5 2.6 signal
441 Dehydration 415 2.5 2.6 signal
442 Procedural Complication 24 2.5 2.5 signal
443 Feeding Disorder 62 2.5 2.5 signal
444 Diarrhoea Haemorrhagic 29 2.5 2.5 signal
445 Appendicectomy 11 2.5 2.5 signal
446 Insomnia 822 2.5 2.6 signal
447 Epigastric Discomfort 12 2.5 2.5 signal
448 Glomerular Filtration Rate Decreased 37 2.5 2.5 signal
449 Asthenia 1,145 2.5 2.6 signal
450 Ear Disorder 14 2.5 2.5 signal
451 Rectal Haemorrhage 131 2.5 2.5 signal
452 Tension Headache 13 2.5 2.5 signal
453 Weight Increased 673 2.5 2.5 signal
454 Gastrointestinal Haemorrhage 254 2.5 2.5 signal
455 Cardiogenic Shock 43 2.5 2.5 signal
456 Neuralgia 73 2.5 2.5 signal
457 Eructation 57 2.5 2.5 signal
458 Melaena 66 2.4 2.5 signal
459 Sleep Apnoea Syndrome 57 2.4 2.4 signal
460 Pollakiuria 124 2.4 2.4 signal
461 Deafness 78 2.4 2.4 signal
462 Illness 299 2.4 2.5 signal
463 Abnormal Loss Of Weight 20 2.4 2.4 signal
464 Death 2,528 2.4 2.6 signal
465 Hyperuricaemia 12 2.4 2.4 signal
466 Liver Disorder 129 2.4 2.4 signal
467 Gastrointestinal Infection 26 2.4 2.4 signal
468 Heart Rate Irregular 66 2.4 2.4 signal
469 Leg Amputation 12 2.4 2.4 signal
470 Red Blood Cell Count Decreased 83 2.4 2.4 signal
471 Upper Limb Fracture 58 2.4 2.4 signal
472 Hip Arthroplasty 44 2.4 2.4 signal
473 Influenza Like Illness 239 2.4 2.4 signal
474 Treatment Noncompliance 157 2.4 2.4 signal
475 Varicose Vein 15 2.4 2.4 signal
476 Lethargy 166 2.4 2.4 signal
477 Tachycardia 256 2.4 2.4 signal
478 Eye Operation 13 2.3 2.3 signal
479 Haemorrhoids 56 2.3 2.3 signal
480 Respiratory Disorder 85 2.3 2.3 signal
481 Blood Pressure Fluctuation 68 2.3 2.3 signal
482 Blood Creatinine Increased 184 2.3 2.3 signal
483 Hepatic Enzyme Abnormal 14 2.3 2.3 signal
484 Respiratory Rate Increased 25 2.3 2.3 signal
485 Bacterial Infection 52 2.3 2.3 signal
486 Staphylococcal Bacteraemia 12 2.3 2.3 signal
487 Nasal Discomfort 22 2.3 2.3 signal
488 Therapy Cessation 141 2.3 2.3 signal
489 Immobile 12 2.3 2.3 signal
490 Diverticulum Intestinal 12 2.3 2.3 signal
491 Blood Disorder 22 2.2 2.2 signal
492 Gallbladder Disorder 49 2.2 2.2 signal
493 Endocarditis 14 2.2 2.2 signal
494 Deafness Unilateral 15 2.2 2.2 signal
495 Feeling Of Body Temperature Change 16 2.2 2.2 signal
496 Defaecation Urgency 19 2.2 2.2 signal
497 Oropharyngeal Pain 252 2.2 2.2 signal
498 Nerve Compression 25 2.2 2.2 signal
499 Loss Of Personal Independence In Daily Activities 129 2.2 2.2 signal
500 Joint Swelling 326 2.2 2.2 signal
501 Chills 317 2.2 2.2 signal
502 Limb Injury 73 2.2 2.2 signal
503 Energy Increased 16 2.2 2.2 signal
504 Aspiration 29 2.2 2.2 signal
505 Liver Function Test Increased 57 2.2 2.2 signal
506 Feeling Hot 164 2.2 2.2 signal
507 Electrocardiogram Abnormal 21 2.2 2.2 signal
508 Thyroid Disorder 41 2.2 2.2 signal
509 Gait Inability 88 2.2 2.2 signal
510 Tooth Infection 35 2.2 2.2 signal
511 Temperature Intolerance 27 2.2 2.2 signal
512 Sleep Disorder 184 2.1 2.2 signal
513 Sars-cov-2 Test Positive 35 2.1 2.1 signal
514 Abdominal Pain 608 2.1 2.2 signal
515 Autoimmune Disorder 25 2.1 2.1 signal
516 Frustration Tolerance Decreased 21 2.1 2.1 signal
517 Cardiac Valve Disease 15 2.1 2.1 signal
518 Constipation 563 2.1 2.2 signal
519 Bundle Branch Block Right 12 2.1 2.1 signal
520 Sinusitis 266 2.1 2.1 signal
521 Fall 858 2.1 2.1 signal
522 Coronary Artery Stenosis 13 2.1 2.1 signal
523 Systemic Lupus Erythematosus 91 2.1 2.1 signal
524 Emphysema 26 2.1 2.1 signal
525 Hypovolaemia 15 2.1 2.1 signal
526 Haematemesis 65 2.1 2.1 signal
527 Wheezing 151 2.1 2.1 signal
528 Hypokalaemia 117 2.1 2.1 signal
529 Chapped Lips 11 2.1 2.1 signal
530 Subdural Haematoma 36 2.0 2.0 signal
531 Respiratory Distress 69 2.0 2.0 signal
532 Tonsillitis 13 2.0 2.0 signal
533 Pallor 68 2.0 2.0 signal
534 Sepsis 278 2.0 2.0 signal
535 Hypoalbuminaemia 19 2.0 2.0 signal
536 Arrhythmia 118 2.0 2.0 signal
537 Eating Disorder 53 2.0 2.0 signal
538 Intestinal Haemorrhage 14 2.0 2.0 signal
539 Facial Paralysis 21 2.0 2.0 signal
540 Thirst 44 2.0 2.0 signal
541 Blood Potassium Increased 40 2.0 2.0 signal
542 Decubitus Ulcer 20 2.0 2.0 signal
543 Enterocolitis 14 2.0 2.0 signal
544 Pneumonia Aspiration 61 2.0 2.0 signal
545 Tooth Abscess 25 2.0 2.0 no signal
546 Gastrointestinal Sounds Abnormal 12 2.0 2.0 no signal
547 Hip Fracture 78 2.0 2.0 no signal
548 Pulmonary Fibrosis 46 2.0 2.0 no signal
549 Hypophagia 61 2.0 2.0 no signal
550 Laryngitis 26 2.0 2.0 no signal
551 Therapy Partial Responder 36 2.0 2.0 no signal
552 Asthenopia 13 2.0 2.0 no signal
553 Hiatus Hernia 31 2.0 2.0 no signal
554 Periorbital Swelling 13 1.9 1.9 no signal
555 Platelet Count Decreased 252 1.9 1.9 no signal
556 Dry Throat 24 1.9 1.9 no signal
557 Therapy Interrupted 163 1.9 1.9 no signal
558 Tachypnoea 32 1.9 1.9 no signal
559 Incontinence 25 1.9 1.9 no signal
560 Rash Pruritic 126 1.9 1.9 no signal
561 General Physical Health Deterioration 268 1.9 1.9 no signal
562 Angina Pectoris 67 1.9 1.9 no signal
563 Cardiac Arrest 192 1.9 1.9 no signal
564 Diverticulitis 64 1.9 1.9 no signal
565 Arthropod Bite 17 1.9 1.9 no signal
566 Gastrointestinal Pain 25 1.9 1.9 no signal
567 Blood Albumin Decreased 18 1.9 1.9 no signal
568 Urinary Tract Infection 387 1.9 1.9 no signal
569 Covid-19 Pneumonia 27 1.9 1.9 no signal
570 Gingival Pain 18 1.8 1.8 no signal
571 Parosmia 17 1.8 1.8 no signal
572 Product Dose Omission Issue 641 1.8 1.9 no signal
573 Infusion Site Extravasation 14 1.8 1.8 no signal
574 Ageusia 56 1.8 1.8 no signal
575 Hepatomegaly 22 1.8 1.8 no signal
576 Post Procedural Infection 18 1.8 1.8 no signal
577 Dry Mouth 179 1.8 1.8 no signal
578 Abnormal Faeces 18 1.8 1.8 no signal
579 Sneezing 49 1.8 1.8 no signal
580 Hepatic Function Abnormal 81 1.8 1.8 no signal
581 Hypoacusis 93 1.8 1.8 no signal
582 Knee Operation 21 1.8 1.8 no signal
583 Product Administration Error 43 1.8 1.8 no signal
584 Pyrexia 745 1.8 1.8 no signal
585 Tinnitus 99 1.8 1.8 no signal
586 Aphonia 30 1.8 1.8 no signal
587 Prothrombin Time Prolonged 13 1.8 1.8 no signal
588 Ear Infection 57 1.8 1.8 no signal
589 Colon Cancer 32 1.8 1.8 no signal
590 Device Dislocation 93 1.8 1.8 no signal
591 Hepatic Encephalopathy 20 1.7 1.8 no signal
592 Angiopathy 12 1.7 1.7 no signal
593 Back Injury 23 1.7 1.7 no signal
594 Dysphonia 124 1.7 1.7 no signal
595 Walking Aid User 14 1.7 1.7 no signal
596 Pharyngitis 26 1.7 1.7 no signal
597 Muscular Weakness 237 1.7 1.7 no signal
598 Pulmonary Mass 31 1.7 1.7 no signal
599 Extra Dose Administered 83 1.7 1.7 no signal
600 Malnutrition 23 1.7 1.7 no signal
601 Skin Warm 12 1.7 1.7 no signal
602 General Physical Condition Abnormal 14 1.7 1.7 no signal
603 Mood Altered 56 1.7 1.7 no signal
604 Groin Pain 18 1.7 1.7 no signal
605 Scratch 21 1.7 1.7 no signal
606 Cholecystectomy 23 1.7 1.7 no signal
607 Blood Alkaline Phosphatase Increased 50 1.6 1.6 no signal
608 Quality Of Life Decreased 27 1.6 1.6 no signal
609 Orthostatic Hypotension 35 1.6 1.6 no signal
610 Incoherent 13 1.6 1.6 no signal
611 Eye Pain 110 1.6 1.6 no signal
612 Gait Disturbance 381 1.6 1.6 no signal
613 Polyp 13 1.6 1.6 no signal
614 Skin Infection 22 1.6 1.6 no signal
615 Lung Infection 31 1.6 1.6 no signal
616 Acidosis 15 1.6 1.6 no signal
617 Infection 282 1.6 1.6 no signal
618 Ileus 24 1.6 1.6 no signal
619 Cardio-respiratory Arrest 82 1.6 1.6 no signal
620 Adverse Drug Reaction 174 1.6 1.6 no signal
621 Mental Status Changes 54 1.6 1.6 no signal
622 Ankle Fracture 30 1.6 1.6 no signal
623 Pelvic Fracture 15 1.6 1.6 no signal
624 Swelling Face 125 1.6 1.6 no signal
625 Oesophagitis 21 1.6 1.6 no signal
626 Renal Pain 20 1.5 1.5 no signal
627 Face Oedema 32 1.5 1.5 no signal
628 Middle Insomnia 35 1.5 1.5 no signal
629 Spinal Pain 22 1.5 1.5 no signal
630 Autoimmune Hepatitis 13 1.5 1.5 no signal
631 International Normalised Ratio Increased 54 1.5 1.5 no signal
632 Septic Shock 81 1.5 1.5 no signal
633 Joint Injury 40 1.5 1.5 no signal
634 Hernia 36 1.5 1.5 no signal
635 Surgery 108 1.5 1.5 no signal
636 Initial Insomnia 19 1.5 1.5 no signal
637 Contusion 179 1.5 1.5 no signal
638 Thrombosis 150 1.5 1.5 no signal
639 Skin Ulcer 48 1.5 1.5 no signal
640 Muscle Strain 16 1.5 1.5 no signal
641 Injection Site Induration 24 1.5 1.5 no signal
642 Cholecystitis 22 1.5 1.5 no signal
643 Device Failure 28 1.5 1.5 no signal
644 Oral Candidiasis 24 1.5 1.5 no signal
645 Cardiac Murmur 16 1.5 1.5 no signal
646 Hand Fracture 13 1.5 1.5 no signal
647 Joint Stiffness 48 1.5 1.5 no signal
648 Gingival Bleeding 25 1.5 1.5 no signal
649 Vertigo 111 1.5 1.5 no signal
650 Covid-19 322 1.5 1.5 no signal
651 Post Procedural Complication 35 1.5 1.5 no signal
652 Spinal Operation 22 1.5 1.5 no signal
653 Staphylococcal Infection 60 1.5 1.5 no signal
654 Panic Reaction 13 1.5 1.5 no signal
655 Renal Failure 241 1.5 1.5 no signal
656 Wound 50 1.5 1.5 no signal
657 Atrioventricular Block Complete 12 1.5 1.5 no signal
658 Unintentional Medical Device Removal 21 1.5 1.5 no signal
659 Sensitive Skin 13 1.5 1.5 no signal
660 Multiple Organ Dysfunction Syndrome 50 1.5 1.5 no signal
661 Road Traffic Accident 75 1.5 1.5 no signal
662 Apathy 26 1.5 1.5 no signal
663 Haemorrhage 187 1.5 1.5 no signal
664 Unresponsive To Stimuli 46 1.5 1.5 no signal
665 Foot Fracture 34 1.5 1.5 no signal
666 Spinal Compression Fracture 15 1.5 1.5 no signal
667 Gastric Ulcer 34 1.5 1.5 no signal
668 Brain Fog 26 1.5 1.5 no signal
669 Lower Limb Fracture 34 1.5 1.5 no signal
670 Somnolence 357 1.5 1.5 no signal
671 Depressed Mood 93 1.4 1.4 no signal
672 Spinal Fracture 35 1.4 1.4 no signal
673 Burning Sensation 123 1.4 1.4 no signal
674 Ocular Discomfort 19 1.4 1.4 no signal
675 Skin Discolouration 80 1.4 1.4 no signal
676 Dysstasia 51 1.4 1.4 no signal
677 Lymphoedema 12 1.4 1.4 no signal
678 Stress 125 1.4 1.4 no signal
679 Feeling Jittery 33 1.4 1.4 no signal
680 Arthritis 136 1.4 1.4 no signal
681 Formication 12 1.4 1.4 no signal
682 Restlessness 63 1.4 1.4 no signal
683 Aspartate Aminotransferase Increased 91 1.4 1.4 no signal
684 Small Intestinal Obstruction 21 1.4 1.4 no signal
685 Joint Dislocation 18 1.4 1.4 no signal
686 Intestinal Obstruction 64 1.4 1.4 no signal
687 Nephropathy 16 1.4 1.4 no signal
688 Circulatory Collapse 29 1.4 1.4 no signal
689 Clostridium Difficile Colitis 18 1.4 1.4 no signal
690 Cholelithiasis 55 1.4 1.4 no signal
691 Gastritis 44 1.4 1.4 no signal
692 Lacrimation Increased 50 1.4 1.4 no signal
693 Accidental Overdose 61 1.4 1.4 no signal
694 Body Temperature Increased 34 1.4 1.4 no signal
695 Wound Infection 18 1.4 1.4 no signal
696 Myocardial Ischaemia 19 1.4 1.4 no signal
697 Therapeutic Product Effect Incomplete 117 1.4 1.4 no signal
698 Pseudomonas Infection 14 1.4 1.4 no signal
699 Eye Swelling 61 1.3 1.3 no signal
700 Oral Pain 37 1.3 1.3 no signal
701 Cold Sweat 29 1.3 1.3 no signal
702 Uterine Leiomyoma 12 1.3 1.3 no signal
703 Rotator Cuff Syndrome 21 1.3 1.3 no signal
704 End Stage Renal Disease 30 1.3 1.3 no signal
705 Anuria 14 1.3 1.3 no signal
706 Lower Gastrointestinal Haemorrhage 12 1.3 1.3 no signal
707 Appendicitis 15 1.3 1.3 no signal
708 Bladder Disorder 16 1.3 1.3 no signal
709 Dysuria 59 1.3 1.3 no signal
710 Blood Bilirubin Increased 43 1.3 1.3 no signal
711 Lung Neoplasm Malignant 65 1.3 1.3 no signal
712 Laceration 15 1.3 1.3 no signal
713 Lung Infiltration 14 1.3 1.3 no signal
714 Cystitis 50 1.3 1.3 no signal
715 Herpes Zoster 89 1.3 1.3 no signal
716 Increased Appetite 29 1.3 1.3 no signal
717 Gamma-glutamyltransferase Increased 34 1.3 1.3 no signal
718 White Blood Cell Count Increased 59 1.3 1.3 no signal
719 Fracture 29 1.3 1.3 no signal
720 Haemodialysis 13 1.3 1.3 no signal
721 Memory Impairment 210 1.2 1.2 no signal
722 Inflammation 78 1.2 1.2 no signal
723 Erythema 309 1.2 1.2 no signal
724 Product Use Issue 281 1.2 1.2 no signal
725 Vision Blurred 205 1.2 1.2 no signal
726 Micturition Urgency 17 1.2 1.2 no signal
727 Nervousness 78 1.2 1.2 no signal
728 Abortion Induced 14 1.2 1.2 no signal
729 Musculoskeletal Stiffness 130 1.2 1.2 no signal
730 Helicobacter Infection 15 1.2 1.2 no signal
731 Anxiety 419 1.2 1.2 no signal
732 Dysphagia 139 1.2 1.2 no signal
733 Discomfort 89 1.2 1.2 no signal
734 Generalised Tonic-clonic Seizure 24 1.2 1.2 no signal
735 Laboratory Test Abnormal 43 1.2 1.2 no signal
736 Urinary Incontinence 43 1.2 1.2 no signal
737 Splenomegaly 17 1.2 1.2 no signal
738 Paraesthesia 228 1.2 1.2 no signal
739 Aortic Aneurysm 11 1.2 1.2 no signal
740 Full Blood Count Abnormal 15 1.2 1.2 no signal
741 Retinal Detachment 13 1.2 1.2 no signal
742 Scab 16 1.2 1.2 no signal
743 Blood Thyroid Stimulating Hormone Increased 13 1.1 1.1 no signal
744 Vitamin D Decreased 12 1.1 1.1 no signal
745 Haematoma 36 1.1 1.1 no signal
746 Amenorrhoea 23 1.1 1.1 no signal
747 Hypokinesia 20 1.1 1.1 no signal
748 Eye Disorder 45 1.1 1.1 no signal
749 Blood Urine Present 26 1.1 1.1 no signal
750 Dermatitis Allergic 17 1.1 1.1 no signal
751 Balance Disorder 118 1.1 1.1 no signal
752 Hypoaesthesia 204 1.1 1.1 no signal
753 Adverse Reaction 18 1.1 1.1 no signal
754 Lymphadenopathy 48 1.1 1.1 no signal
755 Colitis 51 1.1 1.1 no signal
756 Blood Test Abnormal 19 1.1 1.1 no signal
757 Accident 16 1.1 1.1 no signal
758 Neuropathy Peripheral 127 1.1 1.1 no signal
759 Alanine Aminotransferase Increased 82 1.1 1.1 no signal
760 Impaired Gastric Emptying 17 1.1 1.1 no signal
761 Blood Calcium Decreased 15 1.1 1.1 no signal
762 Sickle Cell Anaemia With Crisis 21 1.1 1.1 no signal
763 Mitral Valve Incompetence 15 1.1 1.1 no signal
764 Candida Infection 22 1.1 1.1 no signal
765 Disability 26 1.1 1.1 no signal
766 Sensory Disturbance 21 1.1 1.1 no signal
767 Lymphoma 20 1.1 1.1 no signal
768 Choking 25 1.1 1.1 no signal
769 Tremor 214 1.1 1.1 no signal
770 Eyelid Oedema 15 1.0 1.0 no signal
771 Confusional State 206 1.0 1.0 no signal
772 Ulcer 20 1.0 1.0 no signal
773 Acute Kidney Injury 191 1.0 1.0 no signal
774 Adrenal Insufficiency 15 1.0 1.0 no signal
775 Device Leakage 53 1.0 1.0 no signal
776 Visual Impairment 154 1.0 1.0 no signal
777 Ventricular Extrasystoles 13 1.0 1.0 no signal
778 Hepatic Steatosis 23 1.0 1.0 no signal
779 Crying 45 1.0 1.0 no signal
780 Vitreous Floaters 12 1.0 1.0 no signal
781 Cerebral Infarction 30 1.0 1.0 no signal
782 Blood Pressure Systolic Increased 24 1.0 1.0 no signal
783 Femur Fracture 38 1.0 1.0 no signal
784 Dysmenorrhoea 16 1.0 1.0 no signal
785 Abdominal Pain Lower 31 1.0 1.0 no signal
786 Hypertension 256 1.0 1.0 no signal
787 Cerebral Haemorrhage 43 1.0 1.0 no signal
788 Post Procedural Haemorrhage 14 1.0 1.0 no signal
789 Cataract 71 1.0 1.0 no signal
790 Eye Haemorrhage 16 1.0 1.0 no signal
791 Fibromyalgia 29 1.0 1.0 no signal
792 Lower Respiratory Tract Infection 54 1.0 1.0 no signal
793 Upper Gastrointestinal Haemorrhage 20 1.0 1.0 no signal
794 Impaired Quality Of Life 17 1.0 1.0 no signal
795 Irritable Bowel Syndrome 25 1.0 1.0 no signal
796 Ill-defined Disorder 71 1.0 1.0 no signal
797 Tooth Disorder 26 0.9 0.9 no signal
798 Hyponatraemia 65 0.9 0.9 no signal
799 Blood Pressure Increased 177 0.9 0.9 no signal
800 Menorrhagia 23 0.9 0.9 no signal
801 Product Dose Omission In Error 31 0.9 0.9 no signal
802 Tenderness 12 0.9 0.9 no signal
803 Pancytopenia 64 0.9 0.9 no signal
804 Sinus Tachycardia 16 0.9 0.9 no signal
805 Panic Attack 41 0.9 0.9 no signal
806 Rash 483 0.9 0.9 no signal
807 Hyperhidrosis 143 0.9 0.9 no signal
808 Pharyngitis Streptococcal 12 0.9 0.9 no signal
809 Anosmia 16 0.9 0.9 no signal
810 Blood Glucose Decreased 53 0.9 0.9 no signal
811 Pancreatitis 58 0.9 0.9 no signal
812 Neoplasm Malignant 73 0.9 0.9 no signal
813 Macular Degeneration 13 0.9 0.9 no signal
814 Tooth Fracture 12 0.9 0.9 no signal
815 Ventricular Tachycardia 18 0.9 0.9 no signal
816 Dental Caries 12 0.9 0.9 no signal
817 Increased Tendency To Bruise 10 0.9 0.9 no signal
818 Wrist Fracture 13 0.9 0.9 no signal
819 Acute Respiratory Distress Syndrome 19 0.9 0.9 no signal
820 Nocturia 13 0.9 0.9 no signal
821 Bradycardia 57 0.9 0.9 no signal
822 Nephrolithiasis 49 0.9 0.9 no signal
823 Mental Impairment 26 0.9 0.9 no signal
824 Eye Infection 12 0.9 0.9 no signal
825 Abscess 17 0.9 0.9 no signal
826 Hypoaesthesia Oral 16 0.9 0.9 no signal
827 Hyperkalaemia 37 0.9 0.9 no signal
828 Pruritus 399 0.9 0.9 no signal
829 Pharyngeal Swelling 10 0.9 0.9 no signal
830 Pulmonary Embolism 99 0.8 0.8 no signal
831 Mental Disorder 45 0.8 0.8 no signal
832 Seizure 118 0.8 0.8 no signal
833 Blood Glucose Abnormal 19 0.8 0.8 no signal
834 Hepatic Failure 31 0.8 0.8 no signal
835 Night Sweats 33 0.8 0.8 no signal
836 Thinking Abnormal 19 0.8 0.8 no signal
837 Drug Dose Omission 169 0.8 0.8 no signal
838 Ocular Hyperaemia 47 0.8 0.8 no signal
839 Transient Ischaemic Attack 34 0.8 0.8 no signal
840 Ventricular Fibrillation 11 0.8 0.8 no signal
841 Disorientation 39 0.8 0.8 no signal
842 Back Disorder 16 0.8 0.8 no signal
843 Subarachnoid Haemorrhage 10 0.8 0.8 no signal
844 Urosepsis 9 0.8 0.8 no signal
845 Hypothyroidism 31 0.8 0.8 no signal
846 Neutrophil Count Increased 10 0.8 0.8 no signal
847 Depression 222 0.8 0.8 no signal
848 Injection Site Discolouration 12 0.8 0.8 no signal
849 Drug Eruption 17 0.8 0.8 no signal
850 Mobility Decreased 69 0.8 0.8 no signal
851 Abnormal Weight Gain 12 0.8 0.8 no signal
852 Fungal Infection 32 0.8 0.8 no signal
853 Knee Arthroplasty 20 0.8 0.8 no signal
854 Off Label Use 831 0.8 0.8 no signal
855 Hypersensitivity 176 0.8 0.8 no signal
856 Hypoglycaemia 46 0.8 0.8 no signal
857 Full Blood Count Decreased 19 0.8 0.8 no signal
858 Dementia 26 0.8 0.8 no signal
859 Chromaturia 21 0.8 0.8 no signal
860 Dysgeusia 69 0.8 0.8 no signal
861 Eye Pruritus 30 0.7 0.7 no signal
862 Hepatic Cancer 22 0.7 0.7 no signal
863 Procedural Pain 25 0.7 0.7 no signal
864 Amnesia 59 0.7 0.7 no signal
865 Salivary Hypersecretion 9 0.7 0.7 no signal
866 Pericarditis 15 0.7 0.7 no signal
867 Obstructive Airways Disorder 10 0.7 0.7 no signal
868 Motor Dysfunction 9 0.7 0.7 no signal
869 Therapeutic Response Unexpected 40 0.7 0.7 no signal
870 Throat Tightness 24 0.7 0.7 no signal
871 Pneumonitis 24 0.7 0.7 no signal
872 Eye Discharge 9 0.7 0.7 no signal
873 C-reactive Protein Increased 32 0.7 0.7 no signal
874 Shock 20 0.7 0.7 no signal
875 Rash Erythematous 41 0.7 0.7 no signal
876 Urinary Retention 29 0.7 0.7 no signal
877 Movement Disorder 28 0.7 0.7 no signal
878 Irritability 52 0.7 0.7 no signal
879 Diabetes Mellitus 66 0.7 0.7 no signal
880 Mass 12 0.7 0.7 no signal
881 Osteoporosis 35 0.7 0.7 no signal
882 Spinal Disorder 8 0.7 0.7 no signal
883 Delirium 29 0.7 0.7 no signal
884 Tendonitis 13 0.7 0.7 no signal
885 Paraesthesia Oral 12 0.7 0.7 no signal
886 Dysarthria 31 0.7 0.7 no signal
887 Bipolar Disorder 9 0.7 0.7 no signal
888 Intervertebral Disc Protrusion 18 0.7 0.7 no signal
889 Speech Disorder 43 0.7 0.7 no signal
890 Pruritus Generalised 18 0.7 0.7 no signal
891 Exposure During Pregnancy 51 0.7 0.7 no signal
892 Hunger 11 0.7 0.7 no signal
893 Haematuria 28 0.7 0.7 no signal
894 Coeliac Disease 8 0.7 0.7 no signal
895 Lip Swelling 27 0.7 0.7 no signal
896 Fear 22 0.7 0.7 no signal
897 White Blood Cell Count Decreased 88 0.7 0.7 no signal
898 Insurance Issue 12 0.7 0.7 no signal
899 Metastases To Liver 14 0.7 0.7 no signal
900 Ovarian Cyst 8 0.6 0.6 no signal
901 Disturbance In Attention 43 0.6 0.6 no signal
902 Hypomagnesaemia 11 0.6 0.6 no signal
903 Inappropriate Schedule Of Product Administration 140 0.6 0.6 no signal
904 Respiratory Arrest 22 0.6 0.6 no signal
905 Incorrect Dose Administered 177 0.6 0.6 no signal
906 Depressed Level Of Consciousness 31 0.6 0.6 no signal
907 Dry Eye 38 0.6 0.6 no signal
908 Chronic Kidney Disease 60 0.6 0.6 no signal
909 Skin Disorder 26 0.6 0.6 no signal
910 Hepatic Enzyme Increased 53 0.6 0.6 no signal
911 Osteoarthritis 33 0.6 0.6 no signal
912 Rash Macular 27 0.6 0.6 no signal
913 Emotional Disorder 24 0.6 0.6 no signal
914 Pharyngeal Oedema 12 0.6 0.6 no signal
915 Petechiae 8 0.6 0.6 no signal
916 Product Use In Unapproved Indication 187 0.6 0.6 no signal
917 Ovarian Cancer 7 0.6 0.6 no signal
918 Arthropathy 42 0.6 0.6 no signal
919 Cerebrovascular Accident 128 0.6 0.6 no signal
920 Device Use Issue 13 0.6 0.6 no signal
921 Breast Pain 8 0.6 0.6 no signal
922 Encephalopathy 18 0.6 0.6 no signal
923 Respiratory Depression 9 0.6 0.6 no signal
924 Asthma 81 0.6 0.6 no signal
925 Injection Site Pruritus 48 0.6 0.6 no signal
926 Osteomyelitis 13 0.6 0.6 no signal
927 Nerve Injury 8 0.6 0.6 no signal
928 Muscle Atrophy 9 0.6 0.6 no signal
929 Therapeutic Response Decreased 43 0.6 0.6 no signal
930 Blindness 29 0.6 0.6 no signal
931 Intestinal Perforation 8 0.6 0.6 no signal
932 Basal Cell Carcinoma 11 0.6 0.6 no signal
933 Device Use Error 24 0.6 0.6 no signal
934 Bronchospasm 10 0.6 0.6 no signal
935 Myelodysplastic Syndrome 10 0.6 0.6 no signal
936 Nodule 9 0.6 0.6 no signal
937 Premature Delivery 11 0.6 0.6 no signal
938 Immune System Disorder 9 0.6 0.6 no signal
939 Euphoric Mood 7 0.6 0.6 no signal
940 Musculoskeletal Disorder 13 0.6 0.6 no signal
941 Urticaria 113 0.6 0.6 no signal
942 Cardiomyopathy 10 0.6 0.6 no signal
943 Glossodynia 15 0.5 0.5 no signal
944 Oral Herpes 13 0.5 0.5 no signal
945 Photosensitivity Reaction 11 0.5 0.5 no signal
946 Coronary Artery Occlusion 9 0.5 0.5 no signal
947 Breast Cancer Metastatic 7 0.5 0.5 no signal
948 Product Use Complaint 10 0.5 0.5 no signal
949 Personality Change 6 0.5 0.5 no signal
950 Scar 11 0.5 0.5 no signal
951 Injection Site Extravasation 8 0.5 0.5 no signal
952 Device Malfunction 43 0.5 0.5 no signal
953 Skin Reaction 9 0.5 0.5 no signal
954 Myocardial Infarction 112 0.5 0.5 no signal
955 Hypocalcaemia 12 0.5 0.5 no signal
956 Hyperglycaemia 23 0.5 0.5 no signal
957 Injection Site Irritation 8 0.5 0.5 no signal
958 Metabolic Acidosis 20 0.5 0.5 no signal
959 Paralysis 9 0.5 0.5 no signal
960 Glaucoma 12 0.5 0.5 no signal
961 Eczema 31 0.5 0.5 no signal
962 Platelet Count Increased 8 0.5 0.5 no signal
963 Vaginal Haemorrhage 26 0.5 0.5 no signal
964 Rheumatoid Arthritis 69 0.5 0.5 no signal
965 Rash Generalised 16 0.5 0.5 no signal
966 Coagulopathy 10 0.5 0.5 no signal
967 Conjunctivitis 11 0.5 0.5 no signal
968 Brain Injury 6 0.5 0.5 no signal
969 Dyskinesia 24 0.5 0.5 no signal
970 Product Prescribing Issue 12 0.5 0.5 no signal
971 Gastric Cancer 15 0.5 0.5 no signal
972 Injection Site Warmth 12 0.5 0.5 no signal
973 Product Availability Issue 13 0.5 0.5 no signal
974 Thyroid Cancer 7 0.5 0.5 no signal
975 Oral Discomfort 8 0.5 0.5 no signal
976 Hepatitis C 7 0.5 0.5 no signal
977 Carpal Tunnel Syndrome 8 0.5 0.5 no signal
978 Blindness Unilateral 8 0.5 0.5 no signal
979 Injection Site Erythema 70 0.5 0.5 no signal
980 Deep Vein Thrombosis 37 0.5 0.5 no signal
981 Aphasia 17 0.5 0.5 no signal
982 Eye Irritation 31 0.5 0.5 no signal
983 Glycosylated Haemoglobin Increased 14 0.5 0.5 no signal
984 Drug Ineffective 730 0.5 0.4 no signal
985 Thrombocytopenia 61 0.4 0.4 no signal
986 Pregnancy 11 0.4 0.4 no signal
987 Acute Myocardial Infarction 16 0.4 0.4 no signal
988 Transaminases Increased 12 0.4 0.4 no signal
989 Drug Hypersensitivity 104 0.4 0.4 no signal
990 Intentional Product Use Issue 47 0.4 0.4 no signal
991 Rash Papular 12 0.4 0.4 no signal
992 Mood Swings 17 0.4 0.4 no signal
993 Drug Interaction 84 0.4 0.4 no signal
994 Impaired Driving Ability 6 0.4 0.4 no signal
995 Epilepsy 16 0.4 0.4 no signal
996 Joint Range Of Motion Decreased 7 0.4 0.4 no signal
997 Medication Error 29 0.4 0.4 no signal
998 Malignant Melanoma 7 0.4 0.4 no signal
999 Angioedema 23 0.4 0.4 no signal
1000 Drug-induced Liver Injury 16 0.4 0.4 no signal
1001 Blister 29 0.4 0.4 no signal
1002 Device Issue 45 0.4 0.4 no signal
1003 Caesarean Section 6 0.4 0.4 no signal
1004 Device Breakage 20 0.4 0.4 no signal
1005 Inability To Afford Medication 5 0.4 0.4 no signal
1006 Cardiovascular Disorder 13 0.4 0.4 no signal
1007 Blood Glucose Increased 96 0.4 0.4 no signal
1008 Application Site Rash 7 0.4 0.4 no signal
1009 Coronary Artery Disease 15 0.4 0.4 no signal
1010 Nightmare 17 0.4 0.4 no signal
1011 Metastases To Bone 8 0.4 0.4 no signal
1012 Skin Haemorrhage 7 0.4 0.4 no signal
1013 Tendon Rupture 6 0.4 0.4 no signal
1014 Application Site Irritation 6 0.4 0.4 no signal
1015 Jaundice 13 0.4 0.4 no signal
1016 Skin Irritation 22 0.4 0.4 no signal
1017 Skin Fissures 9 0.4 0.4 no signal
1018 Muscle Twitching 11 0.4 0.4 no signal
1019 Poisoning 6 0.4 0.4 no signal
1020 Immunodeficiency 7 0.4 0.4 no signal
1021 Injection Site Swelling 36 0.4 0.4 no signal
1022 Haemorrhage Intracranial 7 0.4 0.4 no signal
1023 Impaired Work Ability 10 0.4 0.4 no signal
1024 Prescribed Overdose 9 0.4 0.4 no signal
1025 Paranoia 8 0.4 0.4 no signal
1026 Dry Skin 60 0.4 0.4 no signal
1027 Blood Glucose Fluctuation 5 0.4 0.4 no signal
1028 Alopecia 89 0.4 0.4 no signal
1029 Delusion 7 0.4 0.4 no signal
1030 Abnormal Behaviour 18 0.4 0.4 no signal
1031 Pancreatitis Acute 10 0.4 0.4 no signal
1032 Activities Of Daily Living Impaired 9 0.4 0.4 no signal
1033 Pancreatic Carcinoma 13 0.4 0.4 no signal
1034 Rebound Effect 5 0.4 0.4 no signal
1035 Pelvic Pain 8 0.4 0.4 no signal
1036 Brain Neoplasm 4 0.4 0.4 no signal
1037 Peritonitis 9 0.4 0.4 no signal
1038 Dermatitis 9 0.4 0.4 no signal
1039 Neoplasm 5 0.4 0.4 no signal
1040 Metastases To Lung 5 0.4 0.4 no signal
1041 Abnormal Dreams 12 0.4 0.4 no signal
1042 Product Packaging Issue 4 0.4 0.4 no signal
1043 Wrong Technique In Product Usage Process 87 0.4 0.3 no signal
1044 Vasculitis 5 0.3 0.3 no signal
1045 Hallucination 32 0.3 0.3 no signal
1046 Squamous Cell Carcinoma 4 0.3 0.3 no signal
1047 Leukaemia 4 0.3 0.3 no signal
1048 Multiple Fractures 7 0.3 0.3 no signal
1049 Product Prescribing Error 10 0.3 0.3 no signal
1050 Agitation 31 0.3 0.3 no signal
1051 Cytopenia 5 0.3 0.3 no signal
1052 Anger 14 0.3 0.3 no signal
1053 Schizophrenia 5 0.3 0.3 no signal
1054 Injury 29 0.3 0.3 no signal
1055 Liver Function Test Abnormal 12 0.3 0.3 no signal
1056 Breast Cancer 38 0.3 0.3 no signal
1057 Pneumocystis Jirovecii Pneumonia 4 0.3 0.3 no signal
1058 Stomatitis 24 0.3 0.3 no signal
1059 Diabetes Mellitus Inadequate Control 7 0.3 0.3 no signal
1060 Device Adhesion Issue 6 0.3 0.3 no signal
1061 Incorrect Product Administration Duration 8 0.3 0.3 no signal
1062 Expired Product Administered 13 0.3 0.3 no signal
1063 Tuberculosis 5 0.3 0.3 no signal
1064 Injection Site Discomfort 4 0.3 0.3 no signal
1065 Plasma Cell Myeloma 15 0.3 0.3 no signal
1066 Injection Site Pain 116 0.3 0.3 no signal
1067 Hallucination, Visual 8 0.3 0.3 no signal
1068 Skin Exfoliation 31 0.3 0.3 no signal
1069 Skin Cancer 8 0.3 0.3 no signal
1070 Pain Of Skin 10 0.3 0.3 no signal
1071 Underdose 27 0.3 0.3 no signal
1072 Intentional Product Misuse 32 0.3 0.3 no signal
1073 Cognitive Disorder 17 0.3 0.3 no signal
1074 Premature Baby 11 0.3 0.3 no signal
1075 Lymphopenia 5 0.3 0.3 no signal
1076 Fistula 4 0.3 0.3 no signal
1077 Drug Effect Less Than Expected 5 0.3 0.3 no signal
1078 Application Site Pruritus 8 0.3 0.3 no signal
1079 Eosinophilia 6 0.3 0.3 no signal
1080 Psychotic Disorder 10 0.3 0.3 no signal
1081 Injection Site Rash 10 0.3 0.3 no signal
1082 Overdose 70 0.3 0.3 no signal
1083 Libido Decreased 4 0.3 0.3 no signal
1084 Drug Administration Error 10 0.3 0.3 no signal
1085 Abasia 8 0.3 0.3 no signal
1086 Coma 15 0.3 0.3 no signal
1087 Colitis Ulcerative 14 0.3 0.3 no signal
1088 Affect Lability 3 0.3 0.3 no signal
1089 Sleep Disorder Due To A General Medical Condition 5 0.3 0.3 no signal
1090 Genital Haemorrhage 4 0.3 0.3 no signal
1091 Cytomegalovirus Infection 5 0.2 0.2 no signal
1092 Aggression 15 0.2 0.2 no signal
1093 Suicidal Ideation 27 0.2 0.2 no signal
1094 Leukopenia 14 0.2 0.2 no signal
1095 Lactic Acidosis 9 0.2 0.2 no signal
1096 Maternal Exposure During Pregnancy 24 0.2 0.2 no signal
1097 Osteonecrosis 9 0.2 0.2 no signal
1098 Inappropriate Schedule Of Drug Administration 19 0.2 0.2 no signal
1099 Device Difficult To Use 17 0.2 0.2 no signal
1100 Skin Burning Sensation 18 0.2 0.2 no signal
1101 Wrong Technique In Device Usage Process 11 0.2 0.2 no signal
1102 Injection Site Haemorrhage 19 0.2 0.2 no signal
1103 Blood Cholesterol Increased 11 0.2 0.2 no signal
1104 Injection Site Reaction 16 0.2 0.2 no signal
1105 Product Dispensing Error 5 0.2 0.2 no signal
1106 Application Site Pain 5 0.2 0.2 no signal
1107 Gynaecomastia 7 0.2 0.2 no signal
1108 Needle Issue 6 0.2 0.2 no signal
1109 Product Preparation Error 4 0.2 0.2 no signal
1110 No Adverse Event 34 0.2 0.2 no signal
1111 Device Delivery System Issue 5 0.2 0.2 no signal
1112 Injection Site Mass 7 0.2 0.2 no signal
1113 Menstruation Irregular 5 0.2 0.2 no signal
1114 Multiple Sclerosis 9 0.2 0.2 no signal
1115 Exposure Via Skin Contact 4 0.1 0.1 no signal
1116 Accidental Exposure To Product 17 0.1 0.1 no signal
1117 Psoriasis 22 0.1 0.1 no signal
1118 Treatment Failure 13 0.1 0.1 no signal
1119 Application Site Erythema 4 0.1 0.1 no signal
1120 Renal Cancer 7 0.1 0.1 no signal
1121 Oesophageal Carcinoma 4 0.1 0.1 no signal
1122 Neutropenia 16 0.1 0.1 no signal
1123 Myelosuppression 4 0.1 0.1 no signal
1124 Emotional Distress 14 0.1 0.1 no signal
1125 Product Adhesion Issue 4 0.1 0.1 no signal
1126 Drug Abuse 9 0.1 0.1 no signal
1127 Bladder Cancer 5 0.1 0.1 no signal
1128 Device Expulsion 3 0.0 0.0 no signal