Reaction

Brain Natriuretic Peptide Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,042 reports · 168 co-occurring drugs

As of the last recalculation, Brain Natriuretic Peptide Increased appears in 3,042 FAERS reports alongside 168 co-occurring drug terms. The strongest observed disproportionality signal is SELEXIPAG (PRR 50.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Selexipag	181	50.9	51.3
Mometasone	125	48.6	48.9
Alirocumab	127	36.1	36.3
Salmeterol Xinafoate	38	30.5	30.7
Ipratropium Bromide	149	30.0	30.1
Metolazone	48	29.7	29.8
Tolvaptan	60	28.8	28.9
Macitentan	258	27.8	27.9
Biotin	120	27.4	27.5
Tadalafil	325	24.7	24.8
Rosuvastatin Calcium	96	24.0	24.1
Tamsulosin Hydrochloride	70	24.0	24.1
Epoprostenol	44	23.3	23.4
Eplerenone	41	22.2	22.3
Mometasone Furoate	128	21.9	22.0
Riociguat	99	21.4	21.5
0Xygen	132	19.1	19.2
Oxygen	132	19.1	19.2
Olmesartan Medoxomil	96	18.8	18.9
Spironolactone	344	18.8	18.8
Torsemide	87	18.5	18.5
Febuxostat Tablets 40 Mg	27	18.3	18.4
Febuxostat Tablets 80 Mg	27	18.3	18.4
Antacid	121	18.1	18.2
Sildenafil Powder,	89	17.6	17.6
Tafamidis	30	17.6	17.6
Digoxin	172	17.3	17.4
Dronedarone	25	16.9	16.9
Bosentan	118	16.6	16.7
Vitamin E	74	16.5	16.5
Sacubitril And Valsartan	250	16.0	16.0
Sildenafil	129	15.9	15.9
Bisoprolol Fumarate	275	15.1	15.2
Carfilzomib	56	13.8	13.8
Calcium Carbonate	128	13.6	13.6
Clopidogrel Bisulfate	179	12.7	12.7
Furosemide	590	12.3	12.3
Bumetanide	46	12.1	12.1
Amiodarone Hydrochloride	19	11.7	11.7
Sildenafil Citrate	199	11.4	11.4
Basiliximab	19	11.1	11.1
Febuxostat	27	11.1	11.1
Isosorbide Dinitrate	29	10.3	10.3
Treprostinil	173	9.9	10.0
Potassium Chloride, Dextrose Monohydrate	124	9.5	9.5
Potassium Chloride Oral	124	9.5	9.5
Potassium Chloride Extended-Release	124	9.5	9.5
Potassium Chloride	148	9.3	9.3
Warfarin	163	9.2	9.2
Ticagrelor	41	8.9	8.9
Albuterol	141	8.4	8.4
Diclofenac	101	8.3	8.3
Warfarin Sodium	55	8.2	8.3
Fluticasone Propionate Nasal	36	8.2	8.2
Carvedilol	154	8.2	8.2
Enalapril Maleate	29	8.1	8.1
Piperacillin And Tazobactam	14	7.5	7.5
Clopidogrel	205	7.5	7.5
Ambrisentan	130	7.4	7.4
Rivaroxaban	206	7.2	7.2
Norepinephrine Bitartrate	15	7.2	7.2
Nitroglycerin	52	6.7	6.7
Promethazine Hydrochloride	18	6.7	6.7
Magnesium Oxide	40	6.6	6.6
Dapagliflozin	30	6.6	6.6
Guaifenesin	29	6.6	6.6
Nebivolol	15	6.5	6.5
Prednisolone	162	6.4	6.4
Prednisolone Oral	162	6.4	6.4
Prednisolone Oral Solution	162	6.4	6.4
Piperacillin Sodium And Tazobactam Sodium	18	6.3	6.3
Colchicine	24	6.3	6.3
Rosuvastatin	177	6.2	6.2
Magnesium Hydroxide	12	6.1	6.1
Aspirin 325 Mg	406	6.1	6.1
Enalapril	49	6.1	6.1
Aspirin 81 Mg	406	6.1	6.1
Romosozumab-Aqqg	12	6.1	6.1
Loperamide Hydrochloride Oral	9	6.0	6.0
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	18	6.0	6.0
Naproxen Sodium, Pseudoephedrine Hydrochloride	18	6.0	6.0
Aspirin	417	6.0	6.0
Docusate Sodium - Sennosides	28	6.0	6.0
Albuterol Sulfate	240	5.9	5.9
Blinatumomab	9	5.9	5.9
Imatinib	15	5.8	5.8
Lubiprostone	8	5.8	5.8
Norepinephrine	9	5.8	5.8
Melphalan Hydrochloride	21	5.8	5.8
Dextrose	11	5.7	5.7
Nifedipine	39	5.7	5.7
Dextrose Monohydrate	11	5.6	5.7
Docusate Sodium	47	5.6	5.6
Diclofenac Sodium	118	5.5	5.5
Enoxaparin Sodium	46	5.5	5.5
Human Insulin	10	5.5	5.5
Evolocumab	125	5.5	5.5
Pemetrexed	17	5.4	5.5
Allopurinol	120	5.4	5.4
Senna Leaf	18	5.4	5.4
Valsartan	80	5.3	5.3
Calcium	111	5.3	5.3
Agalsidase Beta	7	5.2	5.2
Butalbital, Acetaminophen, And Caffeine	8	5.1	5.1
Ibuprofen Capsule	144	5.1	5.1
Ibuprofen Tablet, Film Coated	144	5.1	5.1
Ibupfrofen	144	5.1	5.1
Ibuprofen Tablets Usp, 200Mg	144	5.1	5.1
Ibuprofen Oral	144	5.1	5.1
Ibuprofen Capsules 200 Mg	144	5.1	5.1
Ibuprofen 200 Mg	144	5.1	5.1
Ibuprofen 200Mg	144	5.1	5.1
Dronabinol	6	5.1	5.1
Pioglitazone	32	5.1	5.1
Valsartan Oral	40	5.1	5.1
Pegaspargase	9	5.0	5.0
Fluticasone Propionate	93	5.0	5.0
Heparin Sodium	10	5.0	5.0
Sotalol Hydrochloride	12	5.0	5.0
Sennosides 8.6 Mg Tablets	15	4.9	4.9
Senna	15	4.9	4.9
Ferrous Sulfate	35	4.8	4.8
Loperamide Hcl	9	4.8	4.8
Dexamethasone Sodium Phosphate	7	4.7	4.7
Lisinopril And Hydrochlorothiazide	7	4.7	4.7
Pitavastatin Calcium	7	4.7	4.7
Isosorbide Mononitrate	14	4.6	4.6
Terazosin Hydrochloride	6	4.6	4.6
Midazolam Hydrochloride	18	4.6	4.6
Dofetilide	7	4.6	4.6
Linezolid	19	4.4	4.4
Posaconazole Delayed-Release	7	4.4	4.4
Midazolam	16	4.4	4.4
Apixaban	41	4.2	4.2
Melphalan	14	4.2	4.2
Piperacillin Sodium,Tazobactam Sodium	16	4.1	4.1
Nebivolol Hydrochloride	20	4.1	4.1
Doxorubicin Hydrochloride	19	4.0	4.0
Deferasirox	15	3.9	3.9
Pembrolizumab	58	3.8	3.8
Umeclidinium	5	3.8	3.8
Pemetrexed Disodium	20	3.6	3.6
Nintedanib	16	3.5	3.5
Clozapine	63	3.5	3.5
Encorafenib	5	3.5	3.5
Timolol Maleate	5	3.5	3.5
Posaconazole	8	3.4	3.4
Dutasteride	4	3.4	3.4
Icosapent Ethyl	4	3.2	3.2
Tiotropium Bromide Inhalation Spray	5	3.1	3.1
Imatinib Mesylate	12	3.0	3.0
Entecavir	5	2.9	2.9
Lenvatinib	14	2.9	2.9
Umeclidinium Bromide And Vilanterol Trifenatate	7	2.9	2.9
Polatuzumab Vedotin	4	2.8	2.8
Bortezomib	33	2.5	2.5
Paricalcitol	5	2.4	2.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	2.4	2.4
Sevelamer Carbonate	4	2.4	2.4
Alteplase	5	2.3	2.3
Suvorexant	4	2.1	2.1
Pazopanib Hydrochloride	8	2.0	2.0
Atezolizumab	11	1.9	1.9
Durvalumab	5	1.7	1.7
Hydrocodone Bitartrate	9	1.4	1.4
Minoxidil Foam 5% (Womens)	6	1.2	1.2
Pomalidomide	17	1.1	1.1
Minoxidil	6	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.