Reaction
Drug Tolerance Increased reporting signals
As of the last recalculation, Drug Tolerance Increased appears in 775 FAERS reports alongside 12 co-occurring drug terms. The strongest observed disproportionality signal is OXYCODONE HYDROCHLORIDE (PRR 35.0).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Oxycodone Hydrochloride | 209 | 35.0 | 35.0 |
| Hydrocodone Bitartrate And Acetaminophen | 67 | 34.9 | 34.9 |
| Carisoprodol | 23 | 33.3 | 33.4 |
| Hydromorphone Hydrochloride | 75 | 24.1 | 24.2 |
| Buprenorphine Hydrochloride, Naloxone Hydrochloride | 16 | 18.2 | 18.2 |
| Morphine Sulfate | 71 | 17.2 | 17.2 |
| Amphetamine | 5 | 16.3 | 16.3 |
| Methadone | 22 | 14.2 | 14.2 |
| Oxymorphone Hydrochloride | 4 | 9.3 | 9.3 |
| Fentanyl Citrate | 6 | 9.1 | 9.1 |
| Ethyl Alcohol | 8 | 8.0 | 8.0 |
| Hydrocodone Bitartrate | 9 | 5.6 | 5.6 |