Reaction

Product Closure Removal Difficult reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 989 reports · 12 co-occurring drugs

As of the last recalculation, Product Closure Removal Difficult appears in 989 FAERS reports alongside 12 co-occurring drug terms. The strongest observed disproportionality signal is LATANOPROST (PRR 82.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Latanoprost16482.082.3
Oxybutynin7154.955.0
Brimonidine Tartrate2226.626.6
Moxifloxacin1522.722.8
Lifitegrast1114.314.3
Minoxidil2813.513.5
Dorzolamide Hydrochloride And Timolol Maleate513.413.4
Fremanezumab-Vfrm712.912.9
Teduglutide812.612.6
Timolol610.510.5
Naproxen Sodium Tablet218.58.5
Etonogestrel135.85.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.