Open Source Medicine Foundation
Lot clusters, lot + specific-AE lookup, and (COVID only) dose-denominated rates — from VAERS lot data
Enter a lot number to see its VAERS reports; volume-adjusted z-score flags, seriousness breakdown, and per-lot signal tables across all vaccines.
Open the dashboard →Pick a vaccine, a lot number, and a MedDRA term. COVID lots can show a per-dose rate where doses are known. Other vaccines show counts and percent of that lot’s reports only.
Open the lookup →National multiple-cause mortality by year (CDC WONDER) for myocarditis/pericarditis and Guillain-Barré — a change around 2021 is equally consistent with a vaccine effect and with the pandemic itself. Hypothesis-generating only.
See the trends →The COVID lot-cluster search applied to influenza, varicella, PCV, HPV, DTaP, hepatitis A, MMR and more. Mostly continua, as with COVID. No dose denominators for non-COVID lots.
See all vaccines →Reports, serious reports, and deaths per million doses for each lot, using openVAERS dose denominators. A count-vs-rate scatter shows how lots rank by raw report count versus by rate per dose.
View per-lot rates →Reporting rate per million doses for each adverse event, computed with known lot doses (840M) and with all lots including imputed doses (924M). The rates are stable across both.
View AE rates →Searchable, sortable table of reporting rates for all 11,000+ individual MedDRA adverse-event terms, with summary bars for total, serious, hospitalization, and death rates.
Open the full table →Box-and-whisker plots of how each adverse event’s rate varies from lot to lot — totals, categories, and individual terms — shown crude and age-adjusted.
View distributions →A cluster analysis (Hopkins, silhouette, k-means, density scan) of the reported symptom mix. It did not identify distinct batch-specific clusters; the largest identifiable sources of variation were manufacturer platform and reporting era.
Read the analysis →When the lots flagged for elevated reporting were administered, and to whom — compared against the documented ACIP rollout phases (healthcare workers, then elderly / long-term care) using vaccination date and recipient age.
See the analysis →The raw data behind the COVID analyses: 605 lots with reports, doses, dose-denominated rates, symptom-category profiles, and cluster labels — sortable and filterable.
Browse the data →Home of the OSMF network — open-source pharmacovigilance tools and evidence-based medicine resources.
Track peer-reviewed literature on vaccine safety, pharmacovigilance, and post-market surveillance.
Soft launch — provisional claim grades; not medical advice. Does not contain vaccine lot or VAERS data.
Comprehensive resource on spike protein biology, biodistribution, and clinical implications.
Decentralized trial for PACVS (post-acute COVID-19 vaccination syndrome).
Weekly seminar series for researchers and clinicians studying post-acute COVID-19 vaccination syndrome.