Vaccine ingredients

Vaccines containing gelatin, egg, yeast, polysorbate 80 or neomycin

33 U.S. vaccine brands, with each allergy-relevant ingredient their FDA package insert lists (Section 11) and the amount per dose where the insert gives one.

Read this first. A dash means the insert's ingredient list does not name that substance, not that the product has been tested free of it. Formulations change between presentations and years. If you or your child has a severe allergy, check the current package insert with a clinician before vaccination.
Allergy-relevant ingredients by brand (package insert Section 11)
BrandGelatinEgg proteinYeastPolysorbate 80Neomycin
AbrysvoPfizer Inc. · insert–––Yeslabel quantity–
ActHIBSanofi Pasteur · insert–––––
ArexvyGlaxoSmithKline Biologicals · insert–––Yes0.18 mg–
BexseroGlaxoSmithKline Biologicals · insert–––––
ComirnatyPfizer Inc. / BioNTech · insert–––––
DaptacelSanofi Pasteur · insert–––––
Engerix-BGlaxoSmithKline Biologicals · insert––Yestrace residual––
Fluzone QuadrivalentSanofi Pasteur · insert–Yesresidual from egg-based manufacture–––
Gardasil 9Merck Sharp & Dohme LLC · insert––Yestrace residual (<7 mcg/dose in related labeling)Yes50 mcg–
HavrixGlaxoSmithKline Biologicals · insert––––Yes≤40 ng residual
Heplisav-BDynavax Technologies · insert––Yes≤5.0% of total protein residualYes0.1 mg/mL–
HiberixGlaxoSmithKline Biologicals · insert–––––
Imovax RabiesSanofi Pasteur · insert––––Yes<150 mcg
InfanrixGlaxoSmithKline Biologicals · insert–––Yes≤100 mcg–
IPOLSanofi Pasteur · insert––––Yestrace residual
IxiaroValneva Austria GmbH · insert–––––
M-M-R IIMerck Sharp & Dohme LLC · insertYes14.5 mg–––Yes≈25 mcg
MenveoGlaxoSmithKline Biologicals · insert–––––
NuvaxovidNovavax, Inc. · insert–––Yeslabel quantity–
PedvaxHIBMerck Sharp & Dohme LLC · insert–––––
Prevnar 20Pfizer Inc. · insert––YestraceYes≈100 mcg–
PRIORIXGlaxoSmithKline Biologicals · insert–Yes≤60 ng residual––Yes≤25 mcg residual
Recombivax HBMerck Sharp & Dohme LLC · insert––Yestrace residual––
RotarixGlaxoSmithKline Biologicals · insert–––––
RotaTeqMerck Sharp & Dohme LLC · insert–––Yeslabel quantity–
ShingrixGlaxoSmithKline Biologicals · insert–––Yeslabel quantity–
SpikevaxModernaTX, Inc. · insert–––––
Typhim ViSanofi Pasteur · insert–––––
VaqtaMerck Sharp & Dohme LLC · insert––––Yestrace residual
VarivaxMerck Sharp & Dohme LLC · insertYes≈12.0 mg–––Yestrace
VaxchoraEmergent Travel Health / Bavarian Nordic · insert–––––
VivotifBavarian Nordic / Emergent · insert–––––
YF-VAXSanofi Pasteur · insertYesstabilizer (label quantity)Yesresidual from chick embryo culture–––

Latex in packaging

Natural rubber latex is a packaging question (vial stoppers, syringe tip caps), stated in each insert's "How Supplied" section rather than its ingredient list. This dataset has recorded it for 2 brands so far:

For any other brand, check section 16 of the current insert.

Common questions

Which vaccines contain gelatin?

Among the 33 U.S. vaccine brands in this table, the package inserts list gelatin in: M-M-R II, Varivax, YF-VAX. Check the current insert for the exact product and presentation you receive.

Which vaccines contain egg protein?

Among the 33 U.S. vaccine brands in this table, the package inserts list egg protein in: Fluzone Quadrivalent, PRIORIX, YF-VAX. Check the current insert for the exact product and presentation you receive.

Which vaccines contain yeast?

Among the 33 U.S. vaccine brands in this table, the package inserts list yeast in: Engerix-B, Gardasil 9, Heplisav-B, Prevnar 20, Recombivax HB. Check the current insert for the exact product and presentation you receive.

Which vaccines contain polysorbate 80?

Among the 33 U.S. vaccine brands in this table, the package inserts list polysorbate 80 in: Abrysvo, Arexvy, Gardasil 9, Heplisav-B, Infanrix, Nuvaxovid, Prevnar 20, RotaTeq, Shingrix. Check the current insert for the exact product and presentation you receive.

Which vaccines contain neomycin?

Among the 33 U.S. vaccine brands in this table, the package inserts list neomycin in: Havrix, Imovax Rabies, IPOL, M-M-R II, PRIORIX, Vaqta, Varivax. Check the current insert for the exact product and presentation you receive.

Source: FDA package inserts via DailyMed, compiled per brand in the site's composition dataset (last updated 2026-07-09). Built 2026-10-28. Not medical advice.