Ramipril vs Verapamil: side effects in FDA adverse event reports
At a glance
| Ramipril | Verapamil | |
|---|---|---|
| Drug class | Angiotensin Converting Enzyme Inhibitor | – |
| Brand names | – | Verapamil Hydrochloride |
| FAERS reports | 123,136 | 4,242 |
| Serious | 93% | 91% |
| Death outcome | 13,282 | 948 |
| Boxed warning | Yes FETAL TOXICITY WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning When pregnancy is detected, discontinue ramipril as soon as p | No |
Signals both drugs share
No strong shared signal after removing coding and lab terms.
Labeled signals distinctive to Ramipril
- Pemphigus — n=2,700, PRR 47.1 Labeled adverse reaction
- Sleep disorder due to general medical condition, insomnia type — n=846, PRR 25.7 Labeled (related wording)
- Subcutaneous drug absorption impaired — n=216, PRR 112.1 Labeled (related wording)
Labeled signals distinctive to Verapamil
- Head discomfort — n=155, PRR 43.9 Labeled (related wording)
- Cardiogenic shock — n=111, PRR 38.8 Labeled adverse reaction
- Shock — n=75, PRR 16.3 Labeled adverse reaction
Common questions
Which has more reported side effects, Ramipril or Verapamil?
Ramipril has 123,136 FAERS reports and Verapamil 4,242. More reports does not mean more dangerous: volume follows how widely and how long a drug has been used, prescription vs over-the-counter status, and publicity. The seriousness share (93% vs 91%) is a better like-for-like signal of the kind of problems reported.
Which side effects do Ramipril and Verapamil share?
They share no strong flagged signal after artifacts and lab terms are removed.
Is Ramipril or Verapamil safer?
FAERS cannot answer that: it has no denominator and no comparator. Use this page to see which risks are already on each label and which signals are unlabeled, then check the prescribing information and your clinician for your situation.
Sources: openFDA FAERS pair statistics (OpenPV build 2026-09-14), FDA labels via openFDA, openFDA count queries for seriousness and deaths. Pair chosen because it is a commonly searched comparison. Generated 2026-10-08.