OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Anakinra

1,097 flagged reaction(s) · 102,833 total co-reports · max PRR 11,473.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Human Antichimeric Antibody Positive 302 11,473.4 11,687.4 signal
2 Monocyte Chemotactic Protein-1 Increased 30 7,522.3 7,536.0 signal
3 Infiltration Anaesthesia 22 2,758.2 2,761.8 signal
4 Actinomycotic Sepsis 17 2,664.1 2,666.9 signal
5 Human Anti-human Antibody Test 16 1,823.6 1,825.3 signal
6 Body Height Below Normal 311 1,178.0 1,200.6 signal
7 Chronic Infantile Neurological Cutaneous And Articular Syndrome 9 1,025.8 1,026.3 signal
8 Febrile Infection-related Epilepsy Syndrome 11 725.8 726.3 signal
9 Alpha Tumour Necrosis Factor Increased 30 597.0 598.1 signal
10 Serum Amyloid A Protein Increased 46 534.0 535.5 signal
11 Ankle Arthroplasty 95 459.9 462.5 signal
12 Autoinflammatory Disease 54 451.3 452.8 signal
13 Tumour Necrosis Factor Receptor-associated Periodic Syndrome 15 417.9 418.3 signal
14 Short Stature 59 371.7 373.0 signal
15 Intestinal Sepsis 50 313.4 314.4 signal
16 Red Blood Cell Sedimentation Rate Abnormal 421 281.3 288.7 signal
17 Joint Destruction 254 246.9 250.7 signal
18 Skin Graft Infection 10 241.1 241.2 signal
19 Propionibacterium Infection 17 236.8 237.1 signal
20 Juvenile Idiopathic Arthritis 371 227.2 232.4 signal
21 Antibody Test Positive 235 207.0 210.0 signal
22 Immune Effector Cell-associated Haematotoxicity 18 201.5 201.7 signal
23 Hair Follicle Tumour Benign 15 195.9 196.1 signal
24 Interleukin Level Increased 70 192.0 192.8 signal
25 Hepatosplenic T-cell Lymphoma 48 188.1 188.6 signal
26 Bone Density Increased 49 177.5 178.1 signal
27 Vexas Syndrome 11 176.8 176.9 signal
28 Herpes Zoster Infection Neurological 19 170.1 170.3 signal
29 Cryopyrin Associated Periodic Syndrome 20 145.8 146.0 signal
30 Body Tinea 58 145.7 146.2 signal
31 Pneumonia Lipoid 13 139.3 139.4 signal
32 Hyperferritinaemia 40 135.9 136.2 signal
33 Soft Tissue Disorder 106 133.2 134.0 signal
34 Polyarthritis 490 130.9 134.8 signal
35 Apparent Death 322 123.0 125.4 signal
36 Testicular Seminoma (pure) 10 121.7 121.8 signal
37 Haemophagocytic Lymphohistiocytosis 631 121.7 126.5 signal
38 Drug Specific Antibody 119 121.5 122.4 signal
39 Growth Failure 30 120.5 120.8 signal
40 Clubbing 34 114.9 115.1 signal
41 Diaphragm Muscle Weakness 13 114.8 114.9 signal
42 Familial Mediterranean Fever 15 106.2 106.3 signal
43 Epidural Lipomatosis 26 102.5 102.7 signal
44 Polyarteritis Nodosa 44 102.3 102.6 signal
45 Breast Ulceration 10 97.9 98.0 signal
46 Oral Mucosal Exfoliation 103 92.7 93.3 signal
47 Rheumatoid Factor Positive 389 91.9 94.1 signal
48 Hypertensive Cardiomyopathy 19 91.6 91.7 signal
49 Spinal Cord Injury Cervical 17 91.5 91.6 signal
50 Immobilisation Syndrome 14 90.5 90.5 signal
51 C-reactive Protein Abnormal 397 84.0 86.0 signal
52 Vasculitic Rash 48 83.8 84.1 signal
53 Soft Tissue Swelling 34 82.0 82.1 signal
54 Juvenile Arthritis 20 81.4 81.5 signal
55 Complications Of Bone Marrow Transplant 21 77.4 77.5 signal
56 Red Blood Cell Sedimentation Rate Increased 635 77.2 80.3 signal
57 Disseminated Mucormycosis 22 76.4 76.5 signal
58 Arthrodesis 57 75.5 75.7 signal
59 Mental Disorder Due To A General Medical Condition 17 72.2 72.3 signal
60 Joint Arthroplasty 95 71.1 71.5 signal
61 Adrenal Suppression 43 68.2 68.4 signal
62 Cold Urticaria 11 66.6 66.7 signal
63 Parvovirus Infection 18 63.2 63.3 signal
64 Steroid Dependence 40 62.8 62.9 signal
65 Alveolar Proteinosis 27 61.4 61.5 signal
66 Splenic Abscess 18 59.5 59.6 signal
67 Synovitis 802 59.1 62.1 signal
68 Adrenal Insufficiency 527 58.5 60.4 signal
69 Wheelchair User 193 57.4 58.1 signal
70 Cytomegalovirus Hepatitis 15 56.3 56.4 signal
71 Congenital Aplasia 12 54.9 54.9 signal
72 Epstein-barr Viraemia 43 52.3 52.5 signal
73 Clear Cell Renal Cell Carcinoma 27 52.2 52.2 signal
74 Smear Cervix Abnormal 56 51.8 51.9 signal
75 Blood Lactate Dehydrogenase Decreased 13 51.1 51.1 signal
76 Ankle Operation 56 50.6 50.8 signal
77 Cellulitis Staphylococcal 24 48.5 48.5 signal
78 Histiocytosis Haematophagic 110 48.2 48.5 signal
79 Drug Tolerance 180 46.7 47.2 signal
80 Post Procedural Contusion 11 45.1 45.1 signal
81 Pneumonia Viral 109 45.0 45.3 signal
82 Fine Motor Skill Dysfunction 97 44.3 44.5 signal
83 Cutaneous Vasculitis 117 43.1 43.4 signal
84 Inhibitory Drug Interaction 52 42.9 43.1 signal
85 Focal Nodular Hyperplasia 16 39.8 39.8 signal
86 Obesity 477 39.2 40.3 signal
87 Anti-cyclic Citrullinated Peptide Antibody Positive 211 38.9 39.4 signal
88 Immune Effector Cell-associated Neurotoxicity Syndrome 162 37.7 38.1 signal
89 Contraindicated Product Administered 846 36.7 38.6 signal
90 Chondrocalcinosis 17 35.2 35.3 signal
91 Acne Cystic 80 34.5 34.7 signal
92 Serum Ferritin Increased 138 34.3 34.6 signal
93 Infection Susceptibility Increased 57 34.0 34.1 signal
94 Laryngeal Stenosis 15 33.9 33.9 signal
95 Systemic Candida 62 32.7 32.9 signal
96 Adenovirus Infection 70 31.8 31.9 signal
97 Varicella Zoster Virus Infection 50 31.5 31.6 signal
98 Polychondritis 10 30.9 30.9 signal
99 Terminal State 153 29.7 29.9 signal
100 Hypofibrinogenaemia 21 28.1 28.2 signal
101 Cushingoid 69 27.7 27.8 signal
102 Injection Site Hypersensitivity 65 27.4 27.6 signal
103 Deformity 196 27.1 27.5 signal
104 Spinal Stenosis 85 27.0 27.1 signal
105 Spondyloarthropathy 12 26.1 26.1 signal
106 Obstructive Sleep Apnoea Syndrome 28 26.0 26.0 signal
107 Pulmonary Thrombosis 214 25.4 25.7 signal
108 Meningitis Listeria 10 25.3 25.3 signal
109 Shoulder Arthroplasty 50 24.4 24.5 signal
110 Graft Versus Host Disease In Gastrointestinal Tract 39 23.7 23.8 signal
111 Myopericarditis 13 23.6 23.6 signal
112 Foot Operation 88 23.1 23.3 signal
113 C-reactive Protein Increased 644 22.9 23.8 signal
114 Multiple-drug Resistance 54 22.6 22.6 signal
115 Immunodeficiency 256 22.5 22.8 signal
116 Viraemia 24 22.3 22.3 signal
117 Anal Stenosis 9 21.7 21.7 signal
118 Meningitis Viral 23 21.6 21.6 signal
119 Hyperplasia 15 21.4 21.4 signal
120 Hand Deformity 215 21.2 21.5 signal
121 Serum Ferritin Decreased 28 21.1 21.1 signal
122 Foot Deformity 180 20.9 21.2 signal
123 Wrist Deformity 10 20.8 20.8 signal
124 Inflammatory Marker Increased 79 20.8 20.9 signal
125 Sensitivity To Weather Change 84 20.7 20.8 signal
126 Nodule 208 20.6 20.8 signal
127 Amyloidosis 27 20.2 20.2 signal
128 Chronic Spontaneous Urticaria 17 19.9 19.9 signal
129 Therapeutic Product Effect Decreased 677 19.7 20.5 signal
130 Diverticulitis 413 19.3 19.7 signal
131 Hepatosplenomegaly 38 19.0 19.0 signal
132 Cytokine Storm 10 18.9 18.9 signal
133 Bradycardia Foetal 12 18.9 18.9 signal
134 Granuloma Skin 12 18.7 18.7 signal
135 Antinuclear Antibody Positive 47 18.6 18.6 signal
136 Obliterative Bronchiolitis 19 18.5 18.5 signal
137 Joint Effusion 99 18.4 18.5 signal
138 Glucose Tolerance Impaired 83 18.2 18.3 signal
139 Septic Shock 610 18.2 18.9 signal
140 Drug Specific Antibody Present 91 18.1 18.2 signal
141 Injection Site Urticaria 333 17.7 18.0 signal
142 Fasciitis 9 17.7 17.7 signal
143 Rheumatoid Arthritis 1,549 17.6 19.4 signal
144 Local Reaction 10 17.5 17.5 signal
145 Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis 33 17.4 17.5 signal
146 Growth Retardation 40 17.4 17.4 signal
147 Serratia Infection 10 17.4 17.4 signal
148 Encephalitis Viral 16 17.0 17.0 signal
149 Central Nervous System Lymphoma 18 16.9 16.9 signal
150 Renal Mass 27 16.9 16.9 signal
151 Gastroenteritis Viral 236 16.8 17.0 signal
152 Arthropathy 725 16.7 17.5 signal
153 Superficial Vein Thrombosis 10 16.0 16.0 signal
154 Transplant Failure 30 15.8 15.9 signal
155 Bone Density Decreased 386 15.7 16.0 signal
156 Drug Intolerance 1,167 15.6 16.7 signal
157 Human Herpesvirus 6 Infection 23 15.5 15.5 signal
158 Cytomegalovirus Infection Reactivation 51 15.4 15.4 signal
159 Alpha Haemolytic Streptococcal Infection 11 15.2 15.2 signal
160 Loss Of Personal Independence In Daily Activities 562 15.2 15.7 signal
161 Endodontic Procedure 30 15.2 15.2 signal
162 Deep Vein Thrombosis Postoperative 23 15.1 15.1 signal
163 Seronegative Arthritis 13 14.9 14.9 signal
164 Product Ineffective For Unapproved Use 16 14.7 14.7 signal
165 Skin Striae 17 14.7 14.7 signal
166 Graft Versus Host Disease In Skin 25 14.6 14.6 signal
167 Pulmonary Fibrosis 216 14.5 14.7 signal
168 Varicella 27 14.5 14.5 signal
169 Normocytic Anaemia 16 14.3 14.3 signal
170 Injection Site Rash 337 14.3 14.5 signal
171 Musculoskeletal Disorder 212 14.2 14.4 signal
172 Cytokine Release Syndrome 211 14.2 14.4 signal
173 Bacterial Sepsis 36 14.2 14.2 signal
174 C-reactive Protein 10 14.2 14.2 signal
175 Dislocation Of Vertebra 24 13.9 13.9 signal
176 Secondary Adrenocortical Insufficiency 16 13.7 13.7 signal
177 Fibromyalgia 257 13.6 13.8 signal
178 Post Transplant Lymphoproliferative Disorder 53 13.6 13.6 signal
179 Cytomegalovirus Viraemia 46 13.5 13.5 signal
180 Hypocalcaemia 198 13.5 13.6 signal
181 Infection Reactivation 12 13.5 13.5 signal
182 Neuroendocrine Carcinoma Of The Skin 10 13.2 13.2 signal
183 Opportunistic Infection 19 13.2 13.2 signal
184 Pseudomonal Sepsis 18 13.1 13.1 signal
185 Acute Graft Versus Host Disease In Skin 28 13.0 13.0 signal
186 Injection Site Inflammation 50 13.0 13.0 signal
187 Acute Febrile Neutrophilic Dermatosis 23 12.8 12.8 signal
188 Joint Swelling 1,190 12.7 13.6 signal
189 Blood Fibrinogen Decreased 11 12.6 12.6 signal
190 Epstein-barr Virus Infection 61 12.6 12.6 signal
191 Therapy Non-responder 428 12.3 12.6 signal
192 Pemphigus 118 12.2 12.3 signal
193 Enterococcal Bacteraemia 10 12.1 12.2 signal
194 Demyelination 39 12.1 12.2 signal
195 Rheumatic Fever 41 12.0 12.1 signal
196 Liver Function Test Abnormal 274 12.0 12.2 signal
197 Rheumatoid Nodule 26 12.0 12.0 signal
198 Mobility Decreased 666 11.9 12.4 signal
199 Lupus Vulgaris 11 11.8 11.9 signal
200 Herpes Zoster 524 11.7 12.0 signal
201 Fungaemia 14 11.5 11.5 signal
202 Drug Tolerance Decreased 25 11.4 11.5 signal
203 Arthritis 688 11.2 11.6 signal
204 Pericarditis 145 11.2 11.2 signal
205 Systemic Inflammatory Response Syndrome 33 11.1 11.1 signal
206 Pneumocystis Jirovecii Infection 10 11.1 11.1 signal
207 Secretion Discharge 107 11.1 11.2 signal
208 Parotitis 10 11.0 11.0 signal
209 Cytopenia 101 10.8 10.9 signal
210 Treatment Failure 690 10.8 11.2 signal
211 Panniculitis 20 10.6 10.6 signal
212 Finger Deformity 40 10.6 10.6 signal
213 Injection Site Pruritus 546 10.5 10.8 signal
214 Blood Parathyroid Hormone Decreased 12 10.3 10.3 signal
215 Injection Site Reaction 547 10.2 10.5 signal
216 Epstein-barr Virus Infection Reactivation 10 10.1 10.1 signal
217 Pyoderma Gangrenosum 28 10.0 10.1 signal
218 Gestational Hypertension 10 10.0 10.0 signal
219 Injection Site Scar 22 10.0 10.0 signal
220 Ill-defined Disorder 473 10.0 10.2 signal
221 Enterobacter Infection 13 9.9 9.9 signal
222 Impaired Quality Of Life 111 9.9 9.9 signal
223 Drug Reaction With Eosinophilia And Systemic Symptoms 197 9.9 10.0 signal
224 Hepatitis 197 9.9 10.0 signal
225 Quality Of Life Decreased 103 9.8 9.9 signal
226 Oral Fungal Infection 21 9.8 9.8 signal
227 Hypertransaminasaemia 52 9.8 9.8 signal
228 Stent Placement 61 9.7 9.7 signal
229 Knee Arthroplasty 156 9.6 9.7 signal
230 Bronchial Hyperreactivity 9 9.6 9.6 signal
231 Vitiligo 17 9.4 9.4 signal
232 Diffuse Large B-cell Lymphoma 56 9.4 9.4 signal
233 Pneumonia Pseudomonal 11 9.3 9.3 signal
234 Blood Pressure Systolic Abnormal 18 9.2 9.3 signal
235 Retinitis 12 9.2 9.2 signal
236 Hepatotoxicity 159 9.2 9.3 signal
237 Photosensitivity Reaction 116 9.0 9.1 signal
238 Tenderness 73 8.9 9.0 signal
239 Facet Joint Syndrome 22 8.9 8.9 signal
240 Adjustment Disorder With Depressed Mood 14 8.9 8.9 signal
241 Respiratory Acidosis 27 8.8 8.8 signal
242 Bronchopulmonary Aspergillosis 53 8.8 8.8 signal
243 Exfoliative Rash 18 8.8 8.8 signal
244 Sacroiliitis 13 8.8 8.8 signal
245 Swollen Joint Count Increased 21 8.6 8.6 signal
246 Purpura 59 8.5 8.6 signal
247 Epicondylitis 10 8.5 8.5 signal
248 Bk Virus Infection 22 8.4 8.4 signal
249 Interstitial Lung Disease 317 8.4 8.5 signal
250 Multiple Organ Dysfunction Syndrome 183 8.4 8.5 signal
251 Erysipelas 33 8.4 8.4 signal
252 Liver Abscess 21 8.3 8.3 signal
253 Pulmonary Function Test Abnormal 10 8.2 8.2 signal
254 Streptococcal Infection 35 8.0 8.1 signal
255 Extremity Necrosis 11 8.0 8.0 signal
256 Scleritis 10 8.0 8.0 signal
257 Infection 902 8.0 8.4 signal
258 Bone Erosion 22 7.9 7.9 signal
259 Histoplasmosis 11 7.9 7.9 signal
260 Vasoplegia Syndrome 10 7.9 7.9 signal
261 Liver Function Test Increased 132 7.9 8.0 signal
262 Drug Use Disorder 51 7.9 7.9 signal
263 Therapeutic Product Effect Incomplete 434 7.8 8.0 signal
264 Drug Ineffective For Unapproved Indication 342 7.8 8.0 signal
265 Injection Site Warmth 126 7.8 7.9 signal
266 Autoimmune Thyroiditis 23 7.8 7.8 signal
267 Injection Site Discolouration 75 7.7 7.8 signal
268 Synovial Cyst 28 7.7 7.7 signal
269 Thrombocytosis 22 7.7 7.7 signal
270 Salmonellosis 10 7.6 7.6 signal
271 Off Label Use 5,160 7.6 10.6 signal
272 Escherichia Sepsis 17 7.5 7.5 signal
273 Type Iv Hypersensitivity Reaction 16 7.5 7.5 signal
274 Injection Site Oedema 10 7.5 7.5 signal
275 Aspergillus Infection 38 7.5 7.5 signal
276 Injection Site Erythema 722 7.5 7.8 signal
277 Mucormycosis 15 7.4 7.5 signal
278 Dermatitis Exfoliative Generalised 20 7.4 7.4 signal
279 Staphylococcal Bacteraemia 25 7.4 7.4 signal
280 Pneumonia Cytomegaloviral 11 7.3 7.3 signal
281 Osteoporotic Fracture 11 7.3 7.3 signal
282 Posterior Reversible Encephalopathy Syndrome 54 7.2 7.3 signal
283 Deep Vein Thrombosis 369 7.2 7.4 signal
284 Condition Aggravated 1,689 7.1 7.8 signal
285 Osteomyelitis 101 7.1 7.2 signal
286 Fungal Skin Infection 22 7.0 7.0 signal
287 Hypokalaemia 250 7.0 7.1 signal
288 Lung Opacity 14 6.9 7.0 signal
289 Intentional Product Use Issue 473 6.9 7.0 signal
290 Immune Thrombocytopenia 24 6.9 6.9 signal
291 Bacteraemia 62 6.7 6.7 signal
292 Peripheral Venous Disease 21 6.7 6.7 signal
293 Limb Discomfort 162 6.7 6.7 signal
294 Escherichia Bacteraemia 12 6.6 6.6 signal
295 Infusion Site Reaction 15 6.6 6.6 signal
296 Disseminated Tuberculosis 13 6.5 6.5 signal
297 Onychomadesis 21 6.5 6.5 signal
298 Inflammation 258 6.4 6.5 signal
299 Injection Site Induration 65 6.4 6.4 signal
300 Prescribed Underdose 100 6.4 6.4 signal
301 Spinal Column Stenosis 24 6.4 6.4 signal
302 Ventricular Dysfunction 13 6.4 6.4 signal
303 Swelling 465 6.4 6.5 signal
304 Glossodynia 111 6.3 6.4 signal
305 Arthritis Infective 23 6.3 6.3 signal
306 Embolism 41 6.3 6.3 signal
307 Oral Herpes 95 6.2 6.3 signal
308 Fibrin D Dimer Increased 17 6.1 6.1 signal
309 Cystitis Haemorrhagic 19 6.0 6.0 signal
310 Splenomegaly 55 6.0 6.0 signal
311 Hyperlipidaemia 56 6.0 6.0 signal
312 Pustular Psoriasis 16 5.9 5.9 signal
313 Localised Infection 112 5.9 5.9 signal
314 Injection Site Irritation 58 5.9 5.9 signal
315 Joint Injury 98 5.8 5.9 signal
316 Pulmonary Embolism 434 5.8 5.9 signal
317 Injection Site Swelling 344 5.8 5.9 signal
318 Hypogammaglobulinaemia 29 5.8 5.8 signal
319 Pleural Effusion 274 5.7 5.8 signal
320 Injection Site Vesicles 27 5.7 5.7 signal
321 Duodenal Ulcer Perforation 33 5.7 5.7 signal
322 Encephalitis 31 5.7 5.7 signal
323 Drug Hypersensitivity 872 5.7 6.0 signal
324 Hidradenitis 39 5.7 5.7 signal
325 Blood Cholesterol Increased 208 5.7 5.8 signal
326 Impaired Healing 143 5.6 5.6 signal
327 Leukopenia 217 5.6 5.6 signal
328 Enterococcal Infection 21 5.5 5.5 signal
329 Loss Of Consciousness 555 5.5 5.7 signal
330 Blood Pressure Diastolic Abnormal 11 5.5 5.5 signal
331 Systemic Lupus Erythematosus 151 5.4 5.5 signal
332 Acute Respiratory Distress Syndrome 75 5.4 5.4 signal
333 Pneumatosis Intestinalis 12 5.4 5.4 signal
334 Hyperuricaemia 17 5.3 5.3 signal
335 Musculoskeletal Pain 218 5.3 5.3 signal
336 Pneumonia Fungal 16 5.3 5.3 signal
337 Sepsis 458 5.2 5.4 signal
338 Cardiac Dysfunction 15 5.2 5.2 signal
339 Hepatic Cytolysis 50 5.2 5.2 signal
340 Psoriasis 533 5.2 5.3 signal
341 Cervical Vertebral Fracture 14 5.2 5.2 signal
342 Viral Infection 135 5.2 5.2 signal
343 Rebound Effect 46 5.2 5.2 signal
344 Clostridium Difficile Colitis 43 5.2 5.2 signal
345 Wound Infection 44 5.2 5.2 signal
346 Stem Cell Transplant 10 5.2 5.2 signal
347 Liver Injury 97 5.1 5.1 signal
348 Injection Site Bruising 316 5.1 5.2 signal
349 Pneumocystis Jirovecii Pneumonia 40 5.1 5.1 signal
350 Haemodynamic Instability 30 5.1 5.1 signal
351 Klebsiella Infection 20 5.1 5.1 signal
352 Guillain-barre Syndrome 19 5.0 5.0 signal
353 Poor Quality Sleep 84 5.0 5.0 signal
354 Symptom Recurrence 23 5.0 5.0 signal
355 Normal Newborn 21 4.9 4.9 signal
356 Spondylitis 14 4.9 4.9 signal
357 Gastrointestinal Perforation 16 4.9 4.9 signal
358 Pericardial Effusion 88 4.9 4.9 signal
359 Arthropod Bite 28 4.9 4.9 signal
360 Immune System Disorder 50 4.8 4.9 signal
361 Immune Reconstitution Inflammatory Syndrome 19 4.8 4.8 signal
362 Pseudomonas Infection 32 4.8 4.8 signal
363 Injection Site Mass 139 4.8 4.8 signal
364 Coronavirus Infection 25 4.8 4.8 signal
365 Candida Infection 62 4.7 4.8 signal
366 Mouth Ulceration 78 4.7 4.7 signal
367 Hypercapnia 11 4.7 4.7 signal
368 Autoimmune Disorder 35 4.7 4.7 signal
369 Staphylococcal Sepsis 18 4.6 4.6 signal
370 Otitis Media 12 4.6 4.6 signal
371 Stomatitis 218 4.6 4.6 signal
372 Osteoarthritis 152 4.6 4.6 signal
373 Skin Disorder 119 4.6 4.6 signal
374 Intentional Product Misuse 310 4.6 4.6 signal
375 Cardiac Tamponade 17 4.5 4.6 signal
376 Bursitis 43 4.5 4.6 signal
377 Brain Death 11 4.5 4.5 signal
378 Cellulitis 178 4.5 4.5 signal
379 Back Disorder 57 4.5 4.5 signal
380 Renal Failure 466 4.4 4.5 signal
381 Myopathy 30 4.4 4.4 signal
382 Impaired Gastric Emptying 44 4.4 4.4 signal
383 Immobile 15 4.4 4.4 signal
384 Mixed Liver Injury 10 4.4 4.4 signal
385 Vasculitis 40 4.4 4.4 signal
386 Thoracic Vertebral Fracture 10 4.3 4.3 signal
387 Blepharospasm 21 4.3 4.3 signal
388 Injection Site Pain 1,026 4.3 4.5 signal
389 Neck Pain 189 4.3 4.3 signal
390 Pyrexia 1,164 4.3 4.5 signal
391 Injection Site Infection 11 4.3 4.3 signal
392 Impaired Work Ability 72 4.3 4.3 signal
393 Hepatic Steatosis 62 4.2 4.3 signal
394 Breast Swelling 9 4.2 4.2 signal
395 Therapy Partial Responder 50 4.2 4.2 signal
396 Enteritis 21 4.2 4.2 signal
397 Escherichia Urinary Tract Infection 14 4.2 4.2 signal
398 Oesophageal Candidiasis 13 4.2 4.2 signal
399 Covid-19 581 4.2 4.3 signal
400 Oligohydramnios 11 4.2 4.2 signal
401 Lymphadenopathy 116 4.2 4.2 signal
402 Tonsillitis 17 4.2 4.2 signal
403 Live Birth 27 4.1 4.1 signal
404 Immunosuppression 28 4.1 4.1 signal
405 Drug Ineffective 4,243 4.1 5.2 signal
406 Product Dose Omission Issue 917 4.1 4.3 signal
407 Toothache 58 4.1 4.1 signal
408 Onychomycosis 14 4.1 4.1 signal
409 Lung Disorder 156 4.1 4.1 signal
410 Arthritis Bacterial 13 4.1 4.1 signal
411 Haematological Malignancy 9 4.0 4.0 signal
412 Coeliac Disease 31 4.0 4.0 signal
413 Sciatica 50 4.0 4.0 signal
414 Fear Of Injection 22 4.0 4.0 signal
415 Prescribed Overdose 61 4.0 4.0 signal
416 Helicobacter Infection 32 4.0 4.0 signal
417 Ulcer 50 4.0 4.0 signal
418 Thrombosis 253 4.0 4.0 signal
419 Embolic Stroke 11 4.0 4.0 signal
420 Meningitis Aseptic 14 4.0 4.0 signal
421 Disseminated Intravascular Coagulation 44 4.0 4.0 signal
422 Breast Cancer Stage Iii 20 4.0 4.0 signal
423 Thrombotic Microangiopathy 30 3.9 4.0 signal
424 Adverse Reaction 41 3.9 3.9 signal
425 Hypertriglyceridaemia 18 3.9 3.9 signal
426 Blood Lactate Dehydrogenase Increased 49 3.9 3.9 signal
427 Skin Fissures 58 3.9 3.9 signal
428 Failure To Thrive 16 3.9 3.9 signal
429 Musculoskeletal Stiffness 269 3.9 4.0 signal
430 Cytomegalovirus Infection 51 3.9 3.9 signal
431 Oral Pain 68 3.9 3.9 signal
432 Hypernatraemia 15 3.9 3.9 signal
433 Basal Cell Carcinoma 47 3.8 3.8 signal
434 Myositis 27 3.8 3.8 signal
435 Crepitations 9 3.8 3.8 signal
436 Eye Injury 9 3.8 3.8 signal
437 Gestational Diabetes 14 3.8 3.8 signal
438 Tibia Fracture 14 3.8 3.8 signal
439 Grip Strength Decreased 26 3.8 3.8 signal
440 Cytolytic Hepatitis 10 3.8 3.8 signal
441 Spinal Fracture 59 3.8 3.8 signal
442 Pharyngitis Streptococcal 32 3.8 3.8 signal
443 Muscle Injury 24 3.7 3.7 signal
444 Protein Total Decreased 11 3.7 3.7 signal
445 Arthralgia 1,198 3.7 3.9 signal
446 Hepatocellular Injury 41 3.7 3.7 signal
447 Ankylosing Spondylitis 37 3.6 3.6 signal
448 Oedema 153 3.6 3.6 signal
449 Ear Infection 75 3.6 3.6 signal
450 Urticaria 468 3.6 3.7 signal
451 Gait Inability 93 3.6 3.6 signal
452 Injection Site Discomfort 29 3.6 3.6 signal
453 Lupus-like Syndrome 25 3.5 3.5 signal
454 Joint Range Of Motion Decreased 37 3.5 3.5 signal
455 Intestinal Perforation 31 3.5 3.5 signal
456 Deafness Neurosensory 9 3.5 3.5 signal
457 Incorrect Route Of Product Administration 46 3.5 3.5 signal
458 Injection Site Nodule 30 3.5 3.5 signal
459 Urosepsis 25 3.5 3.5 signal
460 Skin Mass 18 3.5 3.5 signal
461 Abscess 43 3.4 3.4 signal
462 Intracranial Pressure Increased 15 3.4 3.4 signal
463 Eosinophilia 47 3.4 3.4 signal
464 Skin Necrosis 14 3.4 3.4 signal
465 Skin Infection 30 3.4 3.4 signal
466 Peripheral Swelling 412 3.4 3.5 signal
467 Vascular Device Infection 12 3.4 3.4 signal
468 Status Epilepticus 30 3.4 3.4 signal
469 Bone Density Abnormal 10 3.4 3.4 signal
470 Venoocclusive Liver Disease 13 3.4 3.4 signal
471 Tooth Disorder 59 3.4 3.4 signal
472 Nystagmus 14 3.4 3.4 signal
473 Wound 73 3.3 3.4 signal
474 Therapeutic Response Decreased 158 3.3 3.4 signal
475 Pain 1,587 3.3 3.5 signal
476 Pulmonary Tuberculosis 11 3.3 3.3 signal
477 Blood Pressure Fluctuation 62 3.3 3.3 signal
478 Product Use Issue 480 3.3 3.3 signal
479 Diarrhoea Haemorrhagic 24 3.3 3.3 signal
480 Umbilical Hernia 12 3.3 3.3 signal
481 Viral Load Increased 10 3.3 3.3 signal
482 Gout 46 3.3 3.3 signal
483 Skin Reaction 36 3.3 3.3 signal
484 Oral Infection 10 3.3 3.3 signal
485 Cardiopulmonary Failure 10 3.3 3.3 signal
486 Leukocytosis 46 3.2 3.2 signal
487 Renal Tubular Necrosis 25 3.2 3.2 signal
488 Hepatic Enzyme Increased 172 3.2 3.2 signal
489 Contusion 243 3.2 3.3 signal
490 Sarcoidosis 12 3.2 3.2 signal
491 Intentional Dose Omission 69 3.2 3.2 signal
492 Hypercholesterolaemia 24 3.2 3.2 signal
493 Hypersensitivity 462 3.2 3.2 signal
494 Spinal Fusion Surgery 10 3.2 3.2 signal
495 Tuberculosis 32 3.2 3.2 signal
496 Agranulocytosis 45 3.1 3.1 signal
497 Cyst 30 3.1 3.1 signal
498 Pharyngitis 30 3.1 3.1 signal
499 Joint Dislocation 25 3.0 3.0 signal
500 Intervertebral Disc Degeneration 22 3.0 3.0 signal
501 Osteopenia 36 3.0 3.0 signal
502 Subarachnoid Haemorrhage 24 3.0 3.0 signal
503 Pulmonary Hypertension 49 3.0 3.0 signal
504 Transaminases Increased 52 3.0 3.0 signal
505 Inflammatory Bowel Disease 23 3.0 3.0 signal
506 Encephalopathy 57 3.0 3.0 signal
507 Escherichia Infection 19 3.0 3.0 signal
508 Folliculitis 24 3.0 3.0 signal
509 Foetal Growth Restriction 14 3.0 3.0 signal
510 Herpes Simplex 15 2.9 2.9 signal
511 Hepatitis B 14 2.9 2.9 signal
512 Psychiatric Symptom 17 2.9 2.9 signal
513 Joint Stiffness 60 2.9 2.9 signal
514 Syringe Issue 40 2.9 2.9 signal
515 Rash 978 2.9 3.0 signal
516 Rash Macular 78 2.9 2.9 signal
517 Psoriatic Arthropathy 90 2.8 2.9 signal
518 Product Label Confusion 13 2.8 2.8 signal
519 Proteinuria 42 2.8 2.8 signal
520 Uveitis 30 2.8 2.8 signal
521 Cataract 131 2.8 2.8 signal
522 Respiratory Failure 161 2.8 2.8 signal
523 Upper-airway Cough Syndrome 18 2.8 2.8 signal
524 Pneumonia Bacterial 20 2.8 2.8 signal
525 Nail Disorder 19 2.8 2.8 signal
526 Tumour Lysis Syndrome 19 2.8 2.8 signal
527 Acute Graft Versus Host Disease 10 2.8 2.8 signal
528 Spinal Compression Fracture 18 2.7 2.7 signal
529 Kidney Infection 42 2.7 2.7 signal
530 Sinusitis 220 2.7 2.7 signal
531 Pancytopenia 119 2.7 2.7 signal
532 Illness 212 2.7 2.7 signal
533 Product Use In Unapproved Indication 514 2.7 2.7 signal
534 Bone Marrow Failure 43 2.7 2.7 signal
535 Vitamin D Decreased 18 2.7 2.7 signal
536 Left Ventricular Dysfunction 14 2.7 2.7 signal
537 Heart Rate Decreased 74 2.7 2.7 signal
538 Pyelonephritis 18 2.7 2.7 signal
539 Osteoporosis 86 2.7 2.7 signal
540 Oral Candidiasis 27 2.6 2.6 signal
541 Laboratory Test Abnormal 61 2.6 2.6 signal
542 Haemolysis 16 2.6 2.6 signal
543 Diverticulum Intestinal 9 2.6 2.6 signal
544 Night Sweats 66 2.6 2.6 signal
545 Coagulopathy 34 2.6 2.6 signal
546 Maternal Exposure During Pregnancy 179 2.6 2.6 signal
547 Rash Pruritic 109 2.6 2.6 signal
548 Covid-19 Pneumonia 24 2.6 2.6 signal
549 Adverse Drug Reaction 180 2.6 2.6 signal
550 Hepatic Enzyme Abnormal 10 2.6 2.6 signal
551 Infusion Related Reaction 132 2.5 2.6 signal
552 Needle Issue 57 2.5 2.5 signal
553 Respiratory Syncytial Virus Infection 17 2.5 2.5 signal
554 Walking Aid User 13 2.5 2.5 signal
555 Angiopathy 11 2.5 2.5 signal
556 Drug-induced Liver Injury 60 2.5 2.5 signal
557 Rash Erythematous 91 2.5 2.5 signal
558 Back Injury 21 2.5 2.5 signal
559 Product Dose Omission In Error 52 2.5 2.5 signal
560 Laryngitis 21 2.5 2.5 signal
561 Hypertension 409 2.5 2.5 signal
562 Influenza 215 2.4 2.5 signal
563 Gastroenteritis 28 2.4 2.4 signal
564 Product Distribution Issue 17 2.4 2.4 signal
565 Colitis Microscopic 9 2.4 2.4 signal
566 Gastrointestinal Toxicity 9 2.4 2.4 signal
567 Hip Arthroplasty 29 2.4 2.4 signal
568 Herpes Virus Infection 11 2.4 2.4 signal
569 Gastrointestinal Infection 17 2.4 2.4 signal
570 Fungal Infection 63 2.4 2.4 signal
571 Skin Warm 11 2.4 2.4 signal
572 Respiratory Tract Infection 49 2.4 2.4 signal
573 Vomiting 877 2.4 2.5 signal
574 Hypercalcaemia 23 2.4 2.4 signal
575 Sleep Disorder Due To General Medical Condition, Insomnia Type 12 2.4 2.4 signal
576 Exostosis 17 2.4 2.4 signal
577 Mass 26 2.4 2.4 signal
578 Myocarditis 21 2.4 2.4 signal
579 Hepatitis Acute 12 2.4 2.4 signal
580 Hysterectomy 16 2.4 2.4 signal
581 Upper Respiratory Tract Infection 85 2.3 2.4 signal
582 Liquid Product Physical Issue 13 2.3 2.3 signal
583 Product Dose Omission 121 2.3 2.3 signal
584 Bronchiectasis 12 2.3 2.3 signal
585 Sars-cov-2 Test Positive 24 2.3 2.3 signal
586 Graft Versus Host Disease 13 2.3 2.3 signal
587 Staphylococcal Infection 59 2.3 2.3 signal
588 Underdose 130 2.3 2.3 signal
589 Pharyngeal Swelling 17 2.3 2.3 signal
590 Furuncle 14 2.3 2.3 signal
591 Conjunctivitis 32 2.2 2.2 signal
592 Mouth Swelling 10 2.2 2.2 signal
593 Hepatomegaly 17 2.2 2.2 signal
594 Drug Resistance 44 2.2 2.2 signal
595 Dermatitis 35 2.1 2.2 signal
596 Spinal Disorder 16 2.1 2.1 signal
597 Anorectal Discomfort 9 2.1 2.1 signal
598 Hypotension 335 2.1 2.2 signal
599 Abdominal Discomfort 278 2.1 2.1 signal
600 Hypoxia 58 2.1 2.1 signal
601 Nasopharyngitis 305 2.1 2.1 signal
602 Meningitis 11 2.1 2.1 signal
603 Exposure During Pregnancy 102 2.1 2.1 signal
604 Aspartate Aminotransferase Increased 87 2.1 2.1 signal
605 Type 2 Diabetes Mellitus 55 2.1 2.1 signal
606 Ulcer Haemorrhage 11 2.1 2.1 signal
607 Tachypnoea 22 2.1 2.1 signal
608 Spinal Pain 19 2.1 2.1 signal
609 Emotional Disorder 50 2.1 2.1 signal
610 Eye Infection 18 2.0 2.0 signal
611 Respiratory Disorder 48 2.0 2.0 signal
612 Alanine Aminotransferase Increased 98 2.0 2.0 signal
613 Ear Pain 31 2.0 2.0 signal
614 Food Allergy 12 2.0 2.0 signal
615 Pregnancy 32 2.0 2.0 signal
616 Renal Impairment 132 2.0 2.0 signal
617 Disability 31 2.0 2.0 no signal
618 Eosinophil Count Increased 13 2.0 2.0 no signal
619 Lymphopenia 22 2.0 2.0 no signal
620 Lip Dry 14 2.0 2.0 no signal
621 Bacterial Infection 29 2.0 2.0 no signal
622 Gastrointestinal Disorder 138 2.0 2.0 no signal
623 Blood Uric Acid Increased 9 2.0 2.0 no signal
624 Malaise 683 2.0 2.0 no signal
625 Atelectasis 15 2.0 2.0 no signal
626 Scratch 16 2.0 2.0 no signal
627 Irritable Bowel Syndrome 33 2.0 2.0 no signal
628 Pulmonary Haemorrhage 12 2.0 2.0 no signal
629 Anaphylactic Reaction 84 1.9 2.0 no signal
630 Haemoglobin Decreased 156 1.9 1.9 no signal
631 Acute Respiratory Failure 29 1.9 1.9 no signal
632 Pneumothorax 24 1.9 1.9 no signal
633 Thrombocytopenia 168 1.9 1.9 no signal
634 Injection Site Haematoma 22 1.9 1.9 no signal
635 Blood Disorder 12 1.9 1.9 no signal
636 Postoperative Wound Infection 10 1.9 1.9 no signal
637 Oropharyngeal Pain 137 1.9 1.9 no signal
638 Drug Eruption 26 1.9 1.9 no signal
639 Drug Effective For Unapproved Indication 43 1.9 1.9 no signal
640 Urinary Tract Infection 250 1.9 1.9 no signal
641 Weight Increased 327 1.9 1.9 no signal
642 Blister 82 1.9 1.9 no signal
643 Concomitant Disease Aggravated 9 1.9 1.9 no signal
644 Anaemia 278 1.9 1.9 no signal
645 Poor Venous Access 15 1.8 1.8 no signal
646 Petechiae 15 1.8 1.8 no signal
647 Disease Progression 170 1.8 1.8 no signal
648 Neurotoxicity 25 1.8 1.8 no signal
649 Sleep Disorder 100 1.8 1.8 no signal
650 Abdominal Pain 332 1.8 1.8 no signal
651 Blood Test Abnormal 20 1.8 1.8 no signal
652 White Blood Cell Count Increased 54 1.8 1.8 no signal
653 Skin Lesion 38 1.8 1.8 no signal
654 Electrocardiogram Abnormal 11 1.8 1.8 no signal
655 Pneumonia 451 1.8 1.8 no signal
656 Stress 100 1.8 1.8 no signal
657 Drug Effect Incomplete 51 1.8 1.8 no signal
658 Body Temperature Increased 28 1.7 1.7 no signal
659 Cholestasis 26 1.7 1.7 no signal
660 Acute Kidney Injury 207 1.7 1.7 no signal
661 Skin Ulcer 35 1.7 1.7 no signal
662 Lymphoma 21 1.7 1.7 no signal
663 Diarrhoea 870 1.7 1.8 no signal
664 Facial Pain 12 1.7 1.7 no signal
665 Shock 30 1.7 1.7 no signal
666 Premature Delivery 21 1.7 1.7 no signal
667 Syncope 131 1.7 1.7 no signal
668 Pulmonary Arterial Hypertension 19 1.7 1.7 no signal
669 Respiratory Distress 36 1.7 1.7 no signal
670 Colitis 49 1.7 1.7 no signal
671 Drug Effect Decreased 71 1.7 1.7 no signal
672 Product Use Complaint 20 1.6 1.6 no signal
673 Migraine 122 1.6 1.6 no signal
674 Lower Respiratory Tract Infection 58 1.6 1.6 no signal
675 Gastrointestinal Pain 14 1.6 1.6 no signal
676 Abortion Induced 12 1.6 1.6 no signal
677 Medication Error 70 1.6 1.6 no signal
678 Rash Generalised 33 1.6 1.6 no signal
679 Transplant Rejection 10 1.6 1.6 no signal
680 Frustration Tolerance Decreased 10 1.6 1.6 no signal
681 Skin Discolouration 57 1.6 1.6 no signal
682 Osteonecrosis 41 1.6 1.6 no signal
683 Respiratory Rate Increased 11 1.6 1.6 no signal
684 Post Procedural Infection 10 1.6 1.6 no signal
685 Hepatic Cirrhosis 23 1.6 1.6 no signal
686 Alopecia 242 1.6 1.6 no signal
687 Bedridden 16 1.6 1.6 no signal
688 Burning Sensation 85 1.5 1.5 no signal
689 Nausea 956 1.5 1.6 no signal
690 Tachycardia 107 1.5 1.5 no signal
691 Neutropenia 162 1.5 1.5 no signal
692 Glaucoma 23 1.5 1.5 no signal
693 Abdominal Pain Upper 244 1.5 1.5 no signal
694 Blood Iron Decreased 14 1.5 1.5 no signal
695 Fear 32 1.5 1.5 no signal
696 Haemodialysis 10 1.5 1.5 no signal
697 Rash Maculo-papular 26 1.5 1.5 no signal
698 Erythema 240 1.5 1.5 no signal
699 Device Related Infection 18 1.5 1.5 no signal
700 Hepatic Failure 35 1.5 1.5 no signal
701 Hiatus Hernia 15 1.5 1.5 no signal
702 Angioedema 51 1.5 1.5 no signal
703 White Blood Cell Count Decreased 125 1.5 1.5 no signal
704 Epilepsy 35 1.5 1.5 no signal
705 Blood Pressure Increased 175 1.5 1.5 no signal
706 Drug Effect Less Than Expected 16 1.4 1.4 no signal
707 Liver Disorder 50 1.4 1.4 no signal
708 Pruritus 425 1.4 1.4 no signal
709 Anal Incontinence 10 1.4 1.4 no signal
710 Adverse Event 103 1.4 1.4 no signal
711 Ligament Sprain 11 1.4 1.4 no signal
712 Paraesthesia Oral 16 1.4 1.4 no signal
713 Rash Papular 25 1.4 1.4 no signal
714 Diabetes Mellitus 85 1.4 1.4 no signal
715 Muscular Weakness 126 1.4 1.4 no signal
716 Body Temperature Decreased 11 1.4 1.4 no signal
717 Lower Limb Fracture 21 1.4 1.4 no signal
718 Myocardial Infarction 191 1.4 1.4 no signal
719 Gamma-glutamyltransferase Increased 24 1.4 1.4 no signal
720 Hypomagnesaemia 15 1.4 1.4 no signal
721 Bronchitis 80 1.4 1.4 no signal
722 Pneumonitis 29 1.4 1.4 no signal
723 Blood Triglycerides Increased 19 1.4 1.4 no signal
724 Platelet Count Increased 14 1.4 1.4 no signal
725 Nephrolithiasis 49 1.4 1.4 no signal
726 Neutrophil Count Increased 11 1.4 1.4 no signal
727 Influenza Like Illness 88 1.4 1.4 no signal
728 Mitral Valve Incompetence 12 1.3 1.3 no signal
729 Pain In Jaw 30 1.3 1.3 no signal
730 Insomnia 282 1.3 1.4 no signal
731 Nervous System Disorder 33 1.3 1.3 no signal
732 Taste Disorder 21 1.3 1.3 no signal
733 Cardiac Failure 84 1.3 1.3 no signal
734 Dermatitis Allergic 13 1.3 1.3 no signal
735 Renal Pain 11 1.3 1.3 no signal
736 Jaundice 28 1.3 1.3 no signal
737 General Physical Health Deterioration 119 1.3 1.3 no signal
738 Limb Injury 28 1.3 1.3 no signal
739 Pain In Extremity 304 1.3 1.3 no signal
740 Acute Hepatic Failure 14 1.3 1.3 no signal
741 Chest Pain 191 1.3 1.3 no signal
742 Premature Baby 31 1.3 1.3 no signal
743 Ventricular Tachycardia 17 1.3 1.3 no signal
744 Back Pain 238 1.3 1.3 no signal
745 Dizziness 509 1.3 1.3 no signal
746 Hyperglycaemia 37 1.3 1.3 no signal
747 Lung Infection 16 1.3 1.3 no signal
748 Neutrophil Count Decreased 41 1.3 1.3 no signal
749 Feeling Abnormal 243 1.3 1.3 no signal
750 Insurance Issue 15 1.3 1.3 no signal
751 Discomfort 61 1.3 1.3 no signal
752 Pulmonary Oedema 45 1.3 1.3 no signal
753 Gastric Ulcer 19 1.3 1.3 no signal
754 Toxic Epidermal Necrolysis 15 1.3 1.3 no signal
755 Fatigue 769 1.3 1.3 no signal
756 Depression 226 1.3 1.3 no signal
757 Gastritis 26 1.3 1.3 no signal
758 Tooth Infection 13 1.3 1.3 no signal
759 Disease Recurrence 47 1.3 1.3 no signal
760 Product Prescribing Issue 20 1.2 1.3 no signal
761 Blood Calcium Decreased 11 1.2 1.2 no signal
762 Hepatic Encephalopathy 9 1.2 1.2 no signal
763 Flank Pain 9 1.2 1.2 no signal
764 Weight Fluctuation 10 1.2 1.2 no signal
765 Delirium 33 1.2 1.2 no signal
766 Blood Urea Increased 16 1.2 1.2 no signal
767 Cholecystitis 11 1.2 1.2 no signal
768 Parkinsonism 9 1.2 1.2 no signal
769 Seasonal Allergy 13 1.2 1.2 no signal
770 Ocular Discomfort 10 1.2 1.2 no signal
771 Eye Swelling 34 1.2 1.2 no signal
772 Blood Pressure Systolic Increased 18 1.2 1.2 no signal
773 Hypothyroidism 29 1.2 1.2 no signal
774 Photophobia 17 1.2 1.2 no signal
775 Blood Pressure Abnormal 18 1.2 1.2 no signal
776 Cystitis 29 1.2 1.2 no signal
777 Foetal Exposure During Pregnancy 73 1.1 1.1 no signal
778 Product Availability Issue 20 1.1 1.1 no signal
779 Brain Fog 13 1.1 1.1 no signal
780 Toxic Skin Eruption 9 1.1 1.1 no signal
781 Sinus Congestion 12 1.1 1.1 no signal
782 Wheezing 52 1.1 1.1 no signal
783 Scar 15 1.1 1.1 no signal
784 Toxicity To Various Agents 146 1.1 1.1 no signal
785 Abortion Spontaneous 35 1.1 1.1 no signal
786 Pruritus Generalised 19 1.1 1.1 no signal
787 Gait Disturbance 166 1.1 1.1 no signal
788 Headache 541 1.1 1.1 no signal
789 Swelling Face 56 1.1 1.1 no signal
790 Blood Creatinine Increased 56 1.1 1.1 no signal
791 Crying 31 1.1 1.1 no signal
792 Local Swelling 15 1.1 1.1 no signal
793 Accident 10 1.1 1.1 no signal
794 Musculoskeletal Chest Pain 13 1.1 1.1 no signal
795 Vertigo 51 1.1 1.1 no signal
796 Unevaluable Event 63 1.1 1.1 no signal
797 Hyperthyroidism 12 1.1 1.1 no signal
798 Myelodysplastic Syndrome 12 1.1 1.1 no signal
799 Rhinorrhoea 53 1.0 1.0 no signal
800 Hypoacusis 35 1.0 1.0 no signal
801 No Therapeutic Response 10 1.0 1.0 no signal
802 Haematocrit Decreased 16 1.0 1.0 no signal
803 Chills 94 1.0 1.0 no signal
804 Multi-organ Failure 14 1.0 1.0 no signal
805 Brain Injury 8 1.0 1.0 no signal
806 Myelosuppression 27 1.0 1.0 no signal
807 Renal Disorder 37 1.0 1.0 no signal
808 Carpal Tunnel Syndrome 11 1.0 1.0 no signal
809 Hepatic Function Abnormal 29 1.0 1.0 no signal
810 Ascites 23 1.0 1.0 no signal
811 Rib Fracture 16 1.0 1.0 no signal
812 Cardiogenic Shock 11 1.0 1.0 no signal
813 Myalgia 131 1.0 1.0 no signal
814 Diplopia 20 1.0 1.0 no signal
815 Pharyngeal Oedema 12 1.0 1.0 no signal
816 Flushing 78 1.0 1.0 no signal
817 Pneumonia Aspiration 19 1.0 1.0 no signal
818 Pancreatitis 40 1.0 1.0 no signal
819 Musculoskeletal Discomfort 13 1.0 1.0 no signal
820 Appendicitis 7 1.0 1.0 no signal
821 Injury Associated With Device 15 0.9 0.9 no signal
822 Dry Eye 36 0.9 0.9 no signal
823 Squamous Cell Carcinoma 7 0.9 0.9 no signal
824 Eye Inflammation 7 0.9 0.9 no signal
825 Skin Laceration 8 0.9 0.9 no signal
826 Clostridium Difficile Infection 16 0.9 0.9 no signal
827 Seizure 84 0.9 0.9 no signal
828 Supraventricular Tachycardia 7 0.9 0.9 no signal
829 Oesophagitis 8 0.9 0.9 no signal
830 Generalised Oedema 9 0.9 0.9 no signal
831 Post Procedural Complication 14 0.9 0.9 no signal
832 Muscle Spasticity 9 0.9 0.9 no signal
833 Cough 203 0.9 0.9 no signal
834 Productive Cough 34 0.9 0.9 no signal
835 Nephropathy Toxic 8 0.9 0.9 no signal
836 Lactic Acidosis 23 0.9 0.9 no signal
837 Eczema 36 0.9 0.9 no signal
838 Brain Oedema 9 0.9 0.9 no signal
839 Febrile Neutropenia 47 0.9 0.9 no signal
840 Dermatitis Contact 8 0.9 0.9 no signal
841 Dyspepsia 69 0.9 0.9 no signal
842 Bone Pain 41 0.9 0.9 no signal
843 Injection Site Haemorrhage 55 0.9 0.9 no signal
844 Tooth Abscess 7 0.9 0.9 no signal
845 Foot Fracture 13 0.9 0.9 no signal
846 Abdominal Distension 71 0.9 0.9 no signal
847 Dyspnoea 384 0.9 0.9 no signal
848 Lymphocyte Count Decreased 12 0.9 0.9 no signal
849 Polyneuropathy 8 0.9 0.9 no signal
850 Feeling Hot 41 0.8 0.8 no signal
851 Injury 47 0.8 0.8 no signal
852 Head Injury 21 0.8 0.8 no signal
853 Hypersomnia 19 0.8 0.8 no signal
854 Lip Swelling 22 0.8 0.8 no signal
855 Therapeutic Response Shortened 21 0.8 0.8 no signal
856 Atrial Fibrillation 64 0.8 0.8 no signal
857 Suicidal Ideation 60 0.8 0.8 no signal
858 Decreased Activity 7 0.8 0.8 no signal
859 Iron Deficiency Anaemia 6 0.8 0.8 no signal
860 Feeding Disorder 13 0.8 0.8 no signal
861 Product Administration Error 13 0.8 0.8 no signal
862 Nerve Compression 6 0.8 0.8 no signal
863 Skin Cancer 14 0.8 0.8 no signal
864 Asthenia 243 0.8 0.8 no signal
865 Road Traffic Accident 27 0.8 0.8 no signal
866 Tendonitis 10 0.8 0.8 no signal
867 Heart Rate Increased 63 0.8 0.8 no signal
868 Nasal Congestion 37 0.8 0.8 no signal
869 Metabolic Acidosis 20 0.8 0.8 no signal
870 Gastric Disorder 22 0.8 0.8 no signal
871 Blood Potassium Decreased 19 0.8 0.8 no signal
872 Oedema Peripheral 77 0.8 0.8 no signal
873 Red Blood Cell Count Decreased 18 0.8 0.8 no signal
874 Respiratory Tract Congestion 10 0.8 0.8 no signal
875 Oxygen Saturation Decreased 35 0.8 0.8 no signal
876 Memory Impairment 86 0.8 0.8 no signal
877 Rotator Cuff Syndrome 8 0.8 0.8 no signal
878 Muscle Tightness 10 0.8 0.8 no signal
879 Scab 7 0.8 0.8 no signal
880 Platelet Count Decreased 65 0.8 0.8 no signal
881 Upper Limb Fracture 12 0.8 0.8 no signal
882 Bone Disorder 11 0.8 0.8 no signal
883 Caesarean Section 7 0.8 0.8 no signal
884 Emphysema 6 0.8 0.8 no signal
885 Cardiac Arrest 49 0.8 0.8 no signal
886 Blood Pressure Decreased 39 0.7 0.7 no signal
887 Gastrooesophageal Reflux Disease 47 0.7 0.7 no signal
888 Hyperbilirubinaemia 6 0.7 0.7 no signal
889 Sneezing 13 0.7 0.7 no signal
890 Dysstasia 17 0.7 0.7 no signal
891 Heart Rate Irregular 13 0.7 0.7 no signal
892 Treatment Noncompliance 31 0.7 0.7 no signal
893 Cardio-respiratory Arrest 24 0.7 0.7 no signal
894 Neoplasm Progression 20 0.7 0.7 no signal
895 Cold Sweat 10 0.7 0.7 no signal
896 Blood Alkaline Phosphatase Increased 14 0.7 0.7 no signal
897 Hypoaesthesia 84 0.7 0.7 no signal
898 Abasia 14 0.7 0.7 no signal
899 Blood Bilirubin Increased 15 0.7 0.7 no signal
900 Product Prescribing Error 13 0.7 0.7 no signal
901 Gastrointestinal Haemorrhage 46 0.7 0.7 no signal
902 Increased Tendency To Bruise 5 0.7 0.7 no signal
903 Dehydration 72 0.7 0.7 no signal
904 Haematoma 14 0.7 0.7 no signal
905 Mental Impairment 13 0.7 0.7 no signal
906 Deafness 14 0.7 0.7 no signal
907 Hemiparesis 9 0.7 0.7 no signal
908 Movement Disorder 17 0.7 0.7 no signal
909 Weight Decreased 146 0.7 0.7 no signal
910 Malignant Melanoma 7 0.7 0.7 no signal
911 Metastases To Lung 6 0.7 0.7 no signal
912 Decreased Appetite 119 0.7 0.7 no signal
913 Ejection Fraction Decreased 8 0.7 0.7 no signal
914 Ocular Hyperaemia 24 0.7 0.7 no signal
915 Pallor 14 0.7 0.7 no signal
916 Swollen Tongue 16 0.7 0.7 no signal
917 Fluid Retention 26 0.7 0.6 no signal
918 Head Discomfort 9 0.6 0.6 no signal
919 Haematochezia 28 0.6 0.6 no signal
920 Epistaxis 38 0.6 0.6 no signal
921 Ataxia 6 0.6 0.6 no signal
922 Bladder Disorder 5 0.6 0.6 no signal
923 Cardiac Disorder 47 0.6 0.6 no signal
924 Glomerular Filtration Rate Decreased 6 0.6 0.6 no signal
925 Hypothermia 5 0.6 0.6 no signal
926 Generalised Tonic-clonic Seizure 8 0.6 0.6 no signal
927 Ear Discomfort 5 0.6 0.6 no signal
928 Frequent Bowel Movements 13 0.6 0.6 no signal
929 Coma 23 0.6 0.6 no signal
930 Injection Site Extravasation 6 0.6 0.6 no signal
931 Chronic Obstructive Pulmonary Disease 25 0.6 0.6 no signal
932 Paraesthesia 74 0.6 0.6 no signal
933 Circulatory Collapse 8 0.6 0.6 no signal
934 Visual Impairment 57 0.6 0.6 no signal
935 Body Height Decreased 5 0.6 0.6 no signal
936 No Adverse Event 82 0.6 0.6 no signal
937 Haemorrhoids 9 0.6 0.6 no signal
938 Amnesia 30 0.6 0.6 no signal
939 Eye Pruritus 15 0.6 0.6 no signal
940 Fall 150 0.6 0.6 no signal
941 Product Storage Error 39 0.6 0.6 no signal
942 Pancreatitis Acute 10 0.6 0.6 no signal
943 Acne 34 0.6 0.6 no signal
944 Confusional State 72 0.6 0.6 no signal
945 Chromaturia 10 0.6 0.6 no signal
946 Drug Interaction 70 0.6 0.6 no signal
947 Restless Legs Syndrome 8 0.6 0.6 no signal
948 Nervousness 23 0.6 0.6 no signal
949 Asthma 49 0.6 0.6 no signal
950 Depressed Mood 23 0.6 0.6 no signal
951 Hyperhidrosis 56 0.6 0.6 no signal
952 Feeling Cold 12 0.5 0.5 no signal
953 Aphonia 6 0.5 0.5 no signal
954 Aphasia 13 0.5 0.5 no signal
955 Post Procedural Haemorrhage 5 0.5 0.5 no signal
956 Eyelid Oedema 5 0.5 0.5 no signal
957 Leukaemia 4 0.5 0.5 no signal
958 Haemorrhage 44 0.5 0.5 no signal
959 Psychomotor Hyperactivity 7 0.5 0.5 no signal
960 Dry Mouth 34 0.5 0.5 no signal
961 Paralysis 6 0.5 0.5 no signal
962 Faeces Discoloured 9 0.5 0.5 no signal
963 Irritability 25 0.5 0.5 no signal
964 Skin Irritation 19 0.5 0.5 no signal
965 Face Oedema 7 0.5 0.5 no signal
966 Hypokinesia 6 0.5 0.5 no signal
967 Decreased Immune Responsiveness 4 0.5 0.5 no signal
968 Haematuria 14 0.5 0.5 no signal
969 Neoplasm Malignant 27 0.5 0.5 no signal
970 Stevens-johnson Syndrome 9 0.5 0.5 no signal
971 Colitis Ulcerative 18 0.5 0.5 no signal
972 Full Blood Count Decreased 8 0.5 0.5 no signal
973 Rectal Haemorrhage 17 0.5 0.5 no signal
974 Dry Throat 4 0.5 0.5 no signal
975 Death 339 0.5 0.5 no signal
976 Haemoptysis 11 0.5 0.5 no signal
977 Drug Dependence 64 0.5 0.5 no signal
978 Cardiovascular Disorder 10 0.5 0.5 no signal
979 Inappropriate Schedule Of Product Administration 69 0.5 0.5 no signal
980 Anaphylactic Shock 10 0.5 0.5 no signal
981 Blood Count Abnormal 6 0.5 0.5 no signal
982 Thyroid Disorder 6 0.5 0.5 no signal
983 Cognitive Disorder 18 0.5 0.5 no signal
984 Peritonitis 8 0.5 0.5 no signal
985 International Normalised Ratio Increased 11 0.5 0.5 no signal
986 Cyanosis 6 0.5 0.5 no signal
987 Dysuria 14 0.5 0.5 no signal
988 Full Blood Count Abnormal 4 0.5 0.5 no signal
989 Dysphonia 22 0.5 0.5 no signal
990 Increased Appetite 7 0.5 0.5 no signal
991 Hunger 5 0.5 0.5 no signal
992 Renal Failure Acute 16 0.5 0.5 no signal
993 Anxiety 105 0.5 0.5 no signal
994 Mood Altered 10 0.5 0.5 no signal
995 Blood Glucose Fluctuation 4 0.5 0.5 no signal
996 Cerebral Haemorrhage 13 0.5 0.5 no signal
997 Central Nervous System Lesion 5 0.5 0.5 no signal
998 Hypertensive Crisis 4 0.5 0.5 no signal
999 Fistula 4 0.5 0.5 no signal
1000 Muscle Spasms 65 0.5 0.4 no signal
1001 Transient Ischaemic Attack 12 0.5 0.4 no signal
1002 Haematemesis 9 0.4 0.4 no signal
1003 Bronchospasm 5 0.4 0.4 no signal
1004 Somnolence 70 0.4 0.4 no signal
1005 Angina Pectoris 10 0.4 0.4 no signal
1006 Apathy 5 0.4 0.4 no signal
1007 Blood Creatine Phosphokinase Increased 10 0.4 0.4 no signal
1008 Dermatitis Atopic 17 0.4 0.4 no signal
1009 Diabetes Mellitus Inadequate Control 6 0.4 0.4 no signal
1010 Skin Exfoliation 28 0.4 0.4 no signal
1011 Chest Discomfort 34 0.4 0.4 no signal
1012 Lethargy 19 0.4 0.4 no signal
1013 Thyroid Cancer 4 0.4 0.4 no signal
1014 Visual Acuity Reduced 11 0.4 0.4 no signal
1015 Hepatitis C 4 0.4 0.4 no signal
1016 Tinnitus 15 0.4 0.4 no signal
1017 Ovarian Cancer 3 0.4 0.4 no signal
1018 Haematotoxicity 3 0.4 0.4 no signal
1019 Middle Insomnia 6 0.4 0.4 no signal
1020 Acute Myeloid Leukaemia 5 0.4 0.4 no signal
1021 Intestinal Obstruction 12 0.4 0.4 no signal
1022 Bradycardia 17 0.4 0.4 no signal
1023 Arrhythmia 15 0.4 0.4 no signal
1024 Metastases To Central Nervous System 4 0.4 0.4 no signal
1025 Hernia 6 0.4 0.4 no signal
1026 Product Quality Issue 42 0.4 0.4 no signal
1027 Affect Lability 3 0.4 0.4 no signal
1028 Sleep Disorder Due To A General Medical Condition 5 0.4 0.4 no signal
1029 Eye Disorder 10 0.4 0.4 no signal
1030 Cholelithiasis 10 0.4 0.4 no signal
1031 Depressed Level Of Consciousness 12 0.4 0.4 no signal
1032 Disorientation 12 0.4 0.4 no signal
1033 Product Physical Issue 6 0.4 0.4 no signal
1034 Incorrect Product Storage 4 0.4 0.4 no signal
1035 Eye Haemorrhage 4 0.4 0.4 no signal
1036 Ovarian Cyst 3 0.4 0.4 no signal
1037 Incorrect Product Administration Duration 6 0.4 0.4 no signal
1038 Hospitalisation 45 0.4 0.4 no signal
1039 Surgery 17 0.4 0.4 no signal
1040 Dysarthria 11 0.4 0.4 no signal
1041 Lung Neoplasm Malignant 12 0.4 0.4 no signal
1042 Withdrawal Syndrome 12 0.4 0.4 no signal
1043 Blindness Unilateral 4 0.4 0.4 no signal
1044 Dialysis 4 0.4 0.4 no signal
1045 Balance Disorder 24 0.4 0.4 no signal
1046 Breast Cancer 26 0.4 0.4 no signal
1047 Anosmia 4 0.4 0.4 no signal
1048 Mental Disorder 12 0.3 0.3 no signal
1049 Throat Irritation 12 0.3 0.3 no signal
1050 Speech Disorder 14 0.3 0.3 no signal
1051 Haemorrhage Intracranial 4 0.3 0.3 no signal
1052 Palpitations 31 0.3 0.3 no signal
1053 Neuropathy Peripheral 25 0.3 0.3 no signal
1054 Dysphagia 25 0.3 0.3 no signal
1055 Impaired Driving Ability 3 0.3 0.3 no signal
1056 Internal Haemorrhage 3 0.3 0.3 no signal
1057 Therapy Interrupted 18 0.3 0.3 no signal
1058 Dry Skin 34 0.3 0.3 no signal
1059 Madarosis 3 0.3 0.3 no signal
1060 Constipation 55 0.3 0.3 no signal
1061 Hot Flush 19 0.3 0.3 no signal
1062 Spinal Operation 3 0.3 0.3 no signal
1063 Tremor 41 0.3 0.3 no signal
1064 Accidental Overdose 9 0.3 0.3 no signal
1065 Tendon Rupture 3 0.3 0.3 no signal
1066 Vision Blurred 33 0.3 0.3 no signal
1067 Cerebrovascular Accident 41 0.3 0.3 no signal
1068 Eye Pain 13 0.3 0.3 no signal
1069 Plasma Cell Myeloma 9 0.3 0.3 no signal
1070 Flatulence 13 0.3 0.3 no signal
1071 Hair Texture Abnormal 3 0.3 0.3 no signal
1072 Blood Glucose Abnormal 4 0.3 0.3 no signal
1073 Blood Glucose Increased 40 0.3 0.3 no signal
1074 Blood Glucose Decreased 10 0.3 0.3 no signal
1075 Eye Irritation 11 0.3 0.3 no signal
1076 Agitation 14 0.2 0.2 no signal
1077 Multiple Sclerosis 9 0.2 0.2 no signal
1078 Multiple Fractures 3 0.2 0.2 no signal
1079 Metrorrhagia 3 0.2 0.2 no signal
1080 Pancreatic Carcinoma 5 0.2 0.2 no signal
1081 Vaginal Haemorrhage 7 0.2 0.2 no signal
1082 Glycosylated Haemoglobin Increased 4 0.2 0.2 no signal
1083 Incorrect Dose Administered 35 0.2 0.2 no signal
1084 Suicide Attempt 9 0.2 0.2 no signal
1085 Skin Burning Sensation 10 0.2 0.2 no signal
1086 Cardiac Failure Congestive 11 0.2 0.2 no signal
1087 Hallucination 10 0.2 0.2 no signal
1088 Emotional Distress 15 0.2 0.2 no signal
1089 Product Complaint 3 0.2 0.2 no signal
1090 Gastric Cancer 3 0.1 0.1 no signal
1091 Breast Cancer Female 3 0.1 0.1 no signal
1092 Malignant Neoplasm Progression 11 0.1 0.1 no signal
1093 Drug Dose Omission 16 0.1 0.1 no signal
1094 Overdose 20 0.1 0.1 no signal
1095 Wrong Technique In Product Usage Process 18 0.1 0.1 no signal
1096 Drug Abuse 7 0.1 0.1 no signal
1097 Device Difficult To Use 4 0.1 0.1 no signal