OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Carfilzomib

1,076 flagged reaction(s) · 76,125 total co-reports · max PRR 524.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Sars-cov-2 Sepsis 15 524.9 525.2 signal
2 Cerebellar Haemangioma 9 508.8 509.0 signal
3 Plasma Cell Myeloma Refractory 459 411.4 418.2 signal
4 Lymphodepletion 9 348.1 348.2 signal
5 Global Longitudinal Strain Abnormal 14 294.0 294.1 signal
6 Plasma Cell Leukaemia 119 185.3 186.1 signal
7 Plasma Cells Increased 14 177.4 177.5 signal
8 Myeloma Cast Nephropathy 23 142.0 142.2 signal
9 Light Chain Disease 23 138.6 138.7 signal
10 Plasmacytoma 188 82.9 83.5 signal
11 Plasma Cell Myeloma Recurrent 322 81.5 82.4 signal
12 Refractory Cancer 18 67.5 67.5 signal
13 Light Chain Analysis Increased 84 66.5 66.6 signal
14 Plasma Cell Myeloma 3,028 62.6 70.0 signal
15 Myelodysplastic Syndrome With Excess Blasts 9 61.8 61.8 signal
16 Pulmonary Interstitial Emphysema Syndrome 10 56.1 56.1 signal
17 Pneumonia Parainfluenzae Viral 12 55.8 55.8 signal
18 Blood Stem Cell Harvest Failure 10 53.6 53.7 signal
19 Atypical Haemolytic Uraemic Syndrome 53 52.4 52.5 signal
20 Monoclonal Immunoglobulin Increased 18 50.7 50.7 signal
21 Light Chain Analysis Abnormal 13 50.0 50.0 signal
22 Donor Specific Antibody Present 9 47.2 47.3 signal
23 Paraproteinaemia 18 45.5 45.5 signal
24 Microangiopathic Haemolytic Anaemia 39 39.4 39.5 signal
25 Minimal Residual Disease 23 38.4 38.4 signal
26 Hyperviscosity Syndrome 14 37.8 37.8 signal
27 Morganella Infection 14 37.3 37.3 signal
28 Bronchopneumopathy 16 33.7 33.7 signal
29 Thrombotic Microangiopathy 415 33.4 33.8 signal
30 Monoclonal Immunoglobulin Present 32 32.5 32.6 signal
31 Haemolytic Uraemic Syndrome 96 31.8 31.9 signal
32 Body Dysmorphic Disorder 15 31.3 31.3 signal
33 B-cell Aplasia 10 30.5 30.5 signal
34 Infestation 10 29.8 29.8 signal
35 Febrile Infection 44 29.6 29.6 signal
36 Therapy Partial Responder 555 28.5 29.1 signal
37 Osteolysis 73 27.5 27.6 signal
38 Bronchial Haemorrhage 11 26.9 27.0 signal
39 Bone Marrow Infiltration 13 26.0 26.0 signal
40 Bile Acid Malabsorption 9 25.3 25.3 signal
41 Cerebral Toxoplasmosis 30 24.7 24.7 signal
42 B-cell Type Acute Leukaemia 23 24.6 24.7 signal
43 Intercepted Product Preparation Error 367 23.1 23.4 signal
44 Listeria Sepsis 8 23.1 23.1 signal
45 Candida Pneumonia 9 21.3 21.3 signal
46 Tumour Lysis Syndrome 242 21.2 21.4 signal
47 Pneumonia Influenzal 33 21.1 21.2 signal
48 Cytopenia 320 20.5 20.7 signal
49 Pneumonia Respiratory Syncytial Viral 22 20.4 20.4 signal
50 Joint Ankylosis 15 20.0 20.0 signal
51 Hypogammaglobulinaemia 165 19.7 19.8 signal
52 Sepsis Syndrome 13 19.7 19.7 signal
53 Disseminated Varicella Zoster Virus Infection 9 19.5 19.5 signal
54 Pneumococcal Sepsis 16 18.8 18.8 signal
55 Meningitis Listeria 12 17.9 17.9 signal
56 B Precursor Type Acute Leukaemia 9 17.6 17.6 signal
57 Blood Immunoglobulin M Increased 14 17.4 17.4 signal
58 Central Nervous System Vasculitis 11 17.2 17.2 signal
59 Cardiac Amyloidosis 23 16.1 16.1 signal
60 Amyloidosis 36 15.9 15.9 signal
61 Influenza A Virus Test Positive 9 15.8 15.8 signal
62 Blood Immunoglobulin A Increased 11 15.6 15.6 signal
63 Parainfluenzae Virus Infection 31 15.2 15.2 signal
64 Oesophageal Infection 9 15.2 15.2 signal
65 Meningoencephalitis Herpetic 9 15.1 15.1 signal
66 Thrombotic Thrombocytopenic Purpura 70 15.1 15.1 signal
67 Immunoglobulins Decreased 27 15.0 15.0 signal
68 Device Related Thrombosis 19 14.7 14.7 signal
69 Superficial Vein Thrombosis 15 14.1 14.1 signal
70 Klebsiella Bacteraemia 17 13.9 13.9 signal
71 Brain Natriuretic Peptide Increased 56 13.8 13.8 signal
72 Escherichia Bacteraemia 41 13.4 13.5 signal
73 Jc Virus Infection 28 13.3 13.3 signal
74 Keratopathy 27 13.0 13.0 signal
75 Bone Lesion 60 12.6 12.6 signal
76 Pulmonary Sepsis 24 12.6 12.6 signal
77 Gastrointestinal Toxicity 78 12.5 12.6 signal
78 Hypergammaglobulinaemia Benign Monoclonal 10 12.3 12.3 signal
79 Pleural Disorder 10 12.1 12.1 signal
80 Protein Total Increased 42 12.0 12.0 signal
81 Device Related Sepsis 32 11.9 11.9 signal
82 Alveolar Proteinosis 9 11.6 11.6 signal
83 Albuminuria 8 11.4 11.4 signal
84 Hypertensive Encephalopathy 9 11.4 11.4 signal
85 Left Atrial Enlargement 8 11.4 11.4 signal
86 Intervertebral Discitis 27 10.8 10.8 signal
87 Secondary Immunodeficiency 17 10.8 10.8 signal
88 Hepatitis B Reactivation 45 10.7 10.7 signal
89 Acute Pulmonary Oedema 79 10.6 10.6 signal
90 Cardiac Dysfunction 51 10.5 10.5 signal
91 Thrombocytopenia 1,543 10.5 11.0 signal
92 Salmonellosis 23 10.4 10.4 signal
93 Hepatitis Viral 11 10.4 10.4 signal
94 Lymphopenia 193 10.4 10.4 signal
95 Pneumonia Pneumococcal 20 10.2 10.2 signal
96 Intercepted Product Administration Error 102 10.0 10.0 signal
97 Pseudomonal Bacteraemia 11 9.9 9.9 signal
98 Covid-19 Pneumonia 155 9.8 9.9 signal
99 Myocardial Necrosis Marker Increased 21 9.8 9.8 signal
100 Diarrhoea Infectious 10 9.7 9.7 signal
101 Microangiopathy 12 9.7 9.7 signal
102 Pathological Fracture 65 9.7 9.7 signal
103 Rhinovirus Infection 48 9.5 9.5 signal
104 Pneumonia Mycoplasmal 10 9.5 9.5 signal
105 Infection In An Immunocompromised Host 9 9.4 9.5 signal
106 Polyneuropathy 145 9.2 9.2 signal
107 N-terminal Prohormone Brain Natriuretic Peptide Increased 17 9.1 9.1 signal
108 Bone Marrow Disorder 36 9.0 9.0 signal
109 Infectious Pleural Effusion 18 9.0 9.0 signal
110 Cytokine Release Syndrome 227 9.0 9.0 signal
111 Acute Left Ventricular Failure 8 8.9 8.9 signal
112 Stem Cell Transplant 29 8.8 8.8 signal
113 Left Ventricular Failure 40 8.8 8.8 signal
114 Klebsiella Sepsis 13 8.7 8.7 signal
115 Blood Immunoglobulin G Increased 14 8.6 8.6 signal
116 Escherichia Sepsis 33 8.6 8.6 signal
117 Systolic Dysfunction 12 8.6 8.6 signal
118 Herpes Zoster Disseminated 9 8.6 8.6 signal
119 H1n1 Influenza 16 8.5 8.5 signal
120 Cardiotoxicity 100 8.5 8.5 signal
121 Essential Hypertension 29 8.4 8.4 signal
122 Embolism Venous 33 8.2 8.2 signal
123 Cardiac Failure Acute 72 8.2 8.2 signal
124 Dilated Cardiomyopathy 10 8.1 8.1 signal
125 Bacterial Sepsis 35 8.1 8.1 signal
126 Ejection Fraction Abnormal 13 8.0 8.0 signal
127 Vascular Pain 10 7.9 7.9 signal
128 Transplant 25 7.9 7.9 signal
129 Soft Tissue Infection 19 7.9 7.9 signal
130 Malignant Hypertension 9 7.9 7.9 signal
131 Haemolytic Anaemia 92 7.7 7.7 signal
132 Hypercalcaemia 126 7.7 7.7 signal
133 Hepatitis E 16 7.7 7.7 signal
134 Posterior Reversible Encephalopathy Syndrome 96 7.6 7.6 signal
135 Haptoglobin Decreased 8 7.5 7.5 signal
136 Diastolic Dysfunction 31 7.5 7.5 signal
137 Protein Total Abnormal 13 7.5 7.5 signal
138 Haematotoxicity 92 7.5 7.5 signal
139 Acute Lymphocytic Leukaemia 28 7.4 7.4 signal
140 Anal Ulcer 8 7.4 7.4 signal
141 Immune Effector Cell-associated Neurotoxicity Syndrome 54 7.2 7.2 signal
142 Infection Susceptibility Increased 21 7.2 7.2 signal
143 Cytomegalovirus Infection Reactivation 40 7.0 7.1 signal
144 Streptococcal Bacteraemia 10 7.0 7.0 signal
145 Left Ventricular Dysfunction 61 6.9 6.9 signal
146 Pneumonia Streptococcal 10 6.8 6.8 signal
147 Pseudomonal Sepsis 16 6.8 6.8 signal
148 Myocardial Injury 9 6.8 6.8 signal
149 Infusion Site Extravasation 56 6.8 6.8 signal
150 Progressive Multifocal Leukoencephalopathy 74 6.7 6.8 signal
151 Ejection Fraction Decreased 139 6.7 6.7 signal
152 Pneumonia Cytomegaloviral 17 6.7 6.7 signal
153 Ventricular Dysfunction 23 6.7 6.7 signal
154 Neutropenic Colitis 18 6.6 6.6 signal
155 Infection Reactivation 10 6.6 6.6 signal
156 Atrial Flutter 69 6.5 6.5 signal
157 Enterocolitis Infectious 8 6.5 6.5 signal
158 Ischaemic Cerebral Infarction 10 6.4 6.4 signal
159 Aplasia 17 6.4 6.4 signal
160 Thrombophlebitis 30 6.4 6.4 signal
161 Circumstance Or Information Capable Of Leading To Medication Error 284 6.4 6.4 signal
162 Febrile Bone Marrow Aplasia 35 6.3 6.3 signal
163 Normocytic Anaemia 12 6.3 6.3 signal
164 Myelosuppression 283 6.2 6.3 signal
165 Pulmonary Hypertension 173 6.2 6.2 signal
166 Neutropenia 1,114 6.2 6.4 signal
167 Haemolysis 63 6.1 6.1 signal
168 Pancytopenia 447 6.0 6.1 signal
169 Myelodysplastic Syndrome 116 6.0 6.0 signal
170 Granulocyte Count Decreased 14 5.9 5.9 signal
171 Palliative Care 12 5.9 5.9 signal
172 Meningitis Bacterial 11 5.8 5.8 signal
173 Bacteraemia 90 5.7 5.8 signal
174 Hypophosphataemia 56 5.7 5.7 signal
175 Occupational Exposure To Product 48 5.6 5.6 signal
176 Febrile Convulsion 9 5.6 5.6 signal
177 Neuropathy Peripheral 693 5.5 5.6 signal
178 Respiratory Tract Infection 190 5.5 5.5 signal
179 Klebsiella Infection 36 5.4 5.4 signal
180 Prerenal Failure 10 5.4 5.4 signal
181 Cardiac Failure 568 5.3 5.4 signal
182 Phlebitis 35 5.1 5.1 signal
183 Fibrosis 21 5.1 5.1 signal
184 Cutaneous T-cell Lymphoma 8 5.1 5.1 signal
185 Staphylococcal Bacteraemia 29 5.0 5.0 signal
186 Venous Thrombosis Limb 14 5.0 5.0 signal
187 Leukopenia 333 5.0 5.1 signal
188 Hypertensive Crisis 74 5.0 5.0 signal
189 Troponin I Increased 11 5.0 5.0 signal
190 Bronchopulmonary Aspergillosis 51 4.9 5.0 signal
191 Acute Respiratory Failure 126 4.9 5.0 signal
192 Blood Disorder 52 4.9 4.9 signal
193 Embolism 54 4.8 4.9 signal
194 Nephrogenic Anaemia 30 4.8 4.8 signal
195 Therapy Non-responder 284 4.8 4.8 signal
196 Pneumonia Bacterial 58 4.8 4.8 signal
197 Febrile Neutropenia 419 4.7 4.8 signal
198 Systemic Inflammatory Response Syndrome 24 4.7 4.7 signal
199 Endocrine Disorder 8 4.7 4.7 signal
200 Nocardiosis 16 4.7 4.7 signal
201 Methaemoglobinaemia 14 4.6 4.6 signal
202 Gene Mutation 12 4.5 4.5 signal
203 Extravasation 25 4.5 4.5 signal
204 Respiratory Tract Infection Viral 14 4.5 4.5 signal
205 Neutrophil Count Abnormal 17 4.5 4.5 signal
206 Acute Coronary Syndrome 50 4.5 4.5 signal
207 Disease Progression 699 4.4 4.5 signal
208 Pneumonia Pseudomonal 9 4.4 4.4 signal
209 Anaemia 1,117 4.4 4.5 signal
210 Squamous Cell Carcinoma Of Skin 35 4.4 4.4 signal
211 Clostridium Difficile Colitis 61 4.3 4.3 signal
212 Ventricular Arrhythmia 21 4.3 4.3 signal
213 Echocardiogram Abnormal 8 4.3 4.3 signal
214 Pulmonary Alveolar Haemorrhage 32 4.3 4.3 signal
215 Atypical Pneumonia 17 4.3 4.3 signal
216 Blood Calcium Increased 50 4.3 4.3 signal
217 Bicytopenia 11 4.3 4.3 signal
218 Jugular Vein Thrombosis 10 4.2 4.2 signal
219 Acute Kidney Injury 862 4.2 4.3 signal
220 Pneumonia Viral 18 4.2 4.2 signal
221 Cardiac Failure Chronic 24 4.2 4.2 signal
222 Platelet Count Decreased 600 4.2 4.3 signal
223 Infusion Site Induration 8 4.2 4.2 signal
224 Spinal Cord Compression 22 4.2 4.2 signal
225 Pneumocystis Jirovecii Pneumonia 56 4.2 4.2 signal
226 Urinary Tract Infection Bacterial 14 4.2 4.2 signal
227 Oesophageal Candidiasis 22 4.2 4.2 signal
228 Respiratory Syncytial Virus Infection 48 4.2 4.2 signal
229 Peripheral Sensory Neuropathy 32 4.1 4.1 signal
230 Laboratory Test Abnormal 161 4.1 4.1 signal
231 Cancer Pain 14 4.1 4.1 signal
232 Neutrophil Count Decreased 220 4.1 4.1 signal
233 Hypervolaemia 26 4.1 4.1 signal
234 Hypocalcaemia 102 4.0 4.1 signal
235 Infusion Site Pain 69 4.0 4.1 signal
236 Ototoxicity 10 4.0 4.0 signal
237 Enterocolitis Haemorrhagic 8 4.0 4.0 signal
238 Quadriplegia 11 4.0 4.0 signal
239 Sepsis 597 4.0 4.1 signal
240 Pseudomembranous Colitis 12 4.0 4.0 signal
241 Systemic Candida 13 3.9 3.9 signal
242 Acute Sinusitis 9 3.9 3.9 signal
243 Anaemia Macrocytic 11 3.9 3.9 signal
244 Compression Fracture 27 3.9 3.9 signal
245 Cytomegalovirus Chorioretinitis 10 3.9 3.9 signal
246 Full Blood Count Decreased 104 3.9 3.9 signal
247 Platelet Count Abnormal 31 3.8 3.9 signal
248 Hyperuricaemia 21 3.8 3.8 signal
249 Aspergillus Infection 33 3.8 3.8 signal
250 Non-cardiac Chest Pain 16 3.8 3.8 signal
251 Multiple Organ Dysfunction Syndrome 140 3.8 3.8 signal
252 Cardiomyopathy 74 3.7 3.8 signal
253 Ventricular Hypokinesia 16 3.7 3.7 signal
254 Septic Shock 214 3.7 3.7 signal
255 Infusion Site Erythema 41 3.7 3.7 signal
256 Upper Respiratory Tract Infection 226 3.7 3.7 signal
257 Pneumonia Fungal 19 3.7 3.7 signal
258 Escherichia Infection 40 3.7 3.7 signal
259 Deep Vein Thrombosis 319 3.7 3.7 signal
260 Thrombophlebitis Superficial 15 3.6 3.6 signal
261 Blood Calcium Abnormal 8 3.6 3.6 signal
262 Troponin Increased 36 3.6 3.6 signal
263 Spinal Compression Fracture 40 3.6 3.6 signal
264 Anxiety Disorder 16 3.6 3.6 signal
265 Acute Myeloid Leukaemia 74 3.6 3.6 signal
266 Congestive Cardiomyopathy 20 3.5 3.5 signal
267 Infection 676 3.5 3.6 signal
268 Myocardial Ischaemia 53 3.5 3.5 signal
269 Neutropenic Sepsis 33 3.4 3.5 signal
270 Sudden Death 49 3.4 3.4 signal
271 Venous Thrombosis 18 3.4 3.4 signal
272 Tricuspid Valve Incompetence 36 3.4 3.4 signal
273 Leukoencephalopathy 17 3.4 3.4 signal
274 Unevaluable Event 343 3.4 3.4 signal
275 Blood Immunoglobulin G Decreased 11 3.4 3.4 signal
276 Product Preparation Error 92 3.3 3.3 signal
277 Product Storage Error 383 3.3 3.3 signal
278 Thoracic Vertebral Fracture 13 3.3 3.3 signal
279 Acute Respiratory Distress Syndrome 78 3.3 3.3 signal
280 Pneumonitis 119 3.3 3.3 signal
281 Pseudomonas Infection 37 3.3 3.3 signal
282 Pulmonary Oedema 195 3.3 3.3 signal
283 Mucosal Inflammation 113 3.2 3.3 signal
284 Pneumonia 1,389 3.2 3.3 signal
285 Refusal Of Treatment By Patient 28 3.2 3.2 signal
286 Bronchiolitis 15 3.2 3.2 signal
287 Retinal Vein Occlusion 12 3.1 3.1 signal
288 Supraventricular Tachycardia 40 3.1 3.1 signal
289 Graft Versus Host Disease 30 3.1 3.1 signal
290 Disease Complication 19 3.1 3.1 signal
291 Device Related Infection 63 3.1 3.1 signal
292 Blood Creatinine Abnormal 14 3.0 3.0 signal
293 Pulseless Electrical Activity 17 3.0 3.0 signal
294 Electrocardiogram T Wave Inversion 9 3.0 3.0 signal
295 Gastric Perforation 11 3.0 3.0 signal
296 Pulmonary Arterial Hypertension 58 3.0 3.0 signal
297 Viral Upper Respiratory Tract Infection 19 3.0 3.0 signal
298 Vein Disorder 20 3.0 3.0 signal
299 Brain Abscess 10 3.0 3.0 signal
300 Skin Toxicity 22 2.9 2.9 signal
301 Infusion Related Reaction 259 2.9 2.9 signal
302 Infusion Site Swelling 24 2.9 2.9 signal
303 Cytomegalovirus Viraemia 17 2.9 2.9 signal
304 Polyomavirus-associated Nephropathy 9 2.9 2.9 signal
305 Pleurisy 23 2.9 2.9 signal
306 Neoplasm Recurrence 13 2.9 2.9 signal
307 Lung Infiltration 34 2.9 2.9 signal
308 Hiccups 31 2.8 2.8 signal
309 Hypoalbuminaemia 29 2.8 2.8 signal
310 Escherichia Urinary Tract Infection 16 2.8 2.8 signal
311 Graft Versus Host Disease In Gastrointestinal Tract 8 2.8 2.8 signal
312 Atrial Fibrillation 365 2.8 2.8 signal
313 Haemophagocytic Lymphohistiocytosis 27 2.8 2.8 signal
314 Second Primary Malignancy 31 2.8 2.8 signal
315 Respiratory Failure 272 2.8 2.8 signal
316 Pulmonary Embolism 354 2.8 2.8 signal
317 Right Ventricular Failure 26 2.8 2.8 signal
318 Acute Myocardial Infarction 108 2.7 2.7 signal
319 Failure To Thrive 19 2.7 2.7 signal
320 Stress Cardiomyopathy 21 2.7 2.7 signal
321 Electrocardiogram St Segment Depression 8 2.7 2.7 signal
322 Nephropathy Toxic 40 2.7 2.7 signal
323 Colitis Ischaemic 24 2.7 2.7 signal
324 Pulmonary Toxicity 25 2.7 2.7 signal
325 Respiratory Distress 98 2.7 2.7 signal
326 Cytomegalovirus Infection 59 2.7 2.7 signal
327 Fluid Overload 52 2.6 2.6 signal
328 White Blood Cell Count Decreased 381 2.6 2.6 signal
329 Cardiac Failure Congestive 284 2.6 2.6 signal
330 Renal Failure 465 2.6 2.6 signal
331 Cerebral Ischaemia 18 2.6 2.6 signal
332 Venoocclusive Liver Disease 17 2.6 2.6 signal
333 Hypoxia 121 2.6 2.6 signal
334 Infusion Site Reaction 10 2.6 2.6 signal
335 Haemoglobin Abnormal 22 2.6 2.6 signal
336 Decubitus Ulcer 28 2.6 2.6 signal
337 Hypoxic-ischaemic Encephalopathy 9 2.6 2.6 signal
338 Pyrexia 1,167 2.5 2.6 signal
339 Hypertension 714 2.5 2.6 signal
340 Metabolic Encephalopathy 10 2.5 2.5 signal
341 Bone Marrow Failure 68 2.5 2.5 signal
342 Keratitis 10 2.5 2.5 signal
343 Sinus Bradycardia 32 2.5 2.5 signal
344 Hepatotoxicity 73 2.5 2.5 signal
345 Mitral Valve Incompetence 37 2.4 2.4 signal
346 Hospice Care 32 2.4 2.4 signal
347 Gastrointestinal Infection 29 2.4 2.4 signal
348 Lung Infection 51 2.4 2.4 signal
349 Nephrotic Syndrome 22 2.4 2.4 signal
350 Squamous Cell Carcinoma 30 2.4 2.4 signal
351 Tachypnoea 43 2.4 2.4 signal
352 Erysipelas 16 2.4 2.4 signal
353 Red Blood Cell Count Decreased 90 2.3 2.4 signal
354 Blood Lactate Dehydrogenase Increased 50 2.3 2.3 signal
355 Mean Cell Volume Increased 8 2.3 2.3 signal
356 Enterococcal Infection 15 2.3 2.3 signal
357 Humerus Fracture 15 2.3 2.3 signal
358 Spinal Pain 36 2.3 2.3 signal
359 Left Ventricular Hypertrophy 13 2.3 2.3 signal
360 Blood Phosphorus Decreased 11 2.3 2.3 signal
361 Clostridium Difficile Infection 65 2.2 2.2 signal
362 Monoplegia 13 2.2 2.2 signal
363 Hepatitis B 18 2.2 2.2 signal
364 Hypomagnesaemia 41 2.2 2.2 signal
365 Hepatic Cytolysis 36 2.2 2.2 signal
366 Autoimmune Haemolytic Anaemia 10 2.2 2.2 signal
367 Bone Pain 169 2.2 2.2 signal
368 Encephalopathy 70 2.1 2.1 signal
369 Inflammatory Marker Increased 14 2.1 2.1 signal
370 Coronavirus Infection 19 2.1 2.1 signal
371 Musculoskeletal Chest Pain 44 2.1 2.1 signal
372 Orthopnoea 9 2.1 2.1 signal
373 Bundle Branch Block Right 13 2.1 2.1 signal
374 Pulmonary Haemorrhage 22 2.1 2.1 signal
375 Bundle Branch Block Left 12 2.1 2.1 signal
376 Localised Oedema 13 2.1 2.1 signal
377 Rash Maculo-papular 62 2.1 2.1 signal
378 Gingivitis 15 2.1 2.1 signal
379 Immunosuppression 24 2.1 2.1 signal
380 Covid-19 489 2.1 2.1 signal
381 Renal Disorder 129 2.1 2.1 signal
382 Off Label Use 2,394 2.1 2.2 signal
383 Cardiac Disorder 258 2.1 2.1 signal
384 Cardiogenic Shock 39 2.0 2.0 signal
385 Femoral Neck Fracture 14 2.0 2.0 signal
386 Hypokalaemia 125 2.0 2.0 signal
387 Pulmonary Congestion 36 2.0 2.0 signal
388 Pleural Effusion 164 2.0 2.0 signal
389 Generalised Oedema 33 2.0 2.0 signal
390 Catheter Site Infection 10 2.0 2.0 no signal
391 Electrocardiogram Qt Prolonged 96 2.0 2.0 no signal
392 Craniocerebral Injury 8 2.0 2.0 no signal
393 Influenza 298 2.0 2.0 no signal
394 Lymphocyte Count Decreased 47 2.0 2.0 no signal
395 Protein Total Decreased 10 2.0 2.0 no signal
396 Arrhythmia 126 2.0 2.0 no signal
397 Lung Adenocarcinoma 8 2.0 2.0 no signal
398 Hyperthermia 20 2.0 2.0 no signal
399 Hyperglycaemia 95 2.0 2.0 no signal
400 Bone Disorder 48 2.0 2.0 no signal
401 Malnutrition 29 1.9 1.9 no signal
402 Urosepsis 24 1.9 1.9 no signal
403 Functional Gastrointestinal Disorder 9 1.9 1.9 no signal
404 Renal Impairment 216 1.9 1.9 no signal
405 Aortic Valve Incompetence 11 1.9 1.9 no signal
406 Intracardiac Thrombus 8 1.9 1.9 no signal
407 Adverse Event 235 1.9 1.9 no signal
408 Anuria 22 1.9 1.9 no signal
409 Haemoglobin Decreased 259 1.9 1.9 no signal
410 White Blood Cell Count Abnormal 16 1.9 1.9 no signal
411 Cholecystitis Acute 14 1.8 1.8 no signal
412 Atelectasis 24 1.8 1.8 no signal
413 Neurotoxicity 43 1.8 1.8 no signal
414 Sinus Tachycardia 35 1.8 1.8 no signal
415 Recurrent Cancer 10 1.8 1.8 no signal
416 Encephalitis 17 1.8 1.8 no signal
417 Malignant Melanoma 33 1.8 1.8 no signal
418 Appetite Disorder 16 1.8 1.8 no signal
419 Drug Resistance 63 1.8 1.8 no signal
420 Atrioventricular Block 19 1.8 1.8 no signal
421 Haemorrhoidal Haemorrhage 12 1.8 1.8 no signal
422 Vascular Device Infection 11 1.8 1.8 no signal
423 Neoplasm 28 1.8 1.8 no signal
424 Overweight 13 1.8 1.8 no signal
425 Walking Aid User 16 1.8 1.8 no signal
426 Blood Creatinine Increased 158 1.8 1.8 no signal
427 Adverse Reaction 32 1.8 1.8 no signal
428 Product Preparation Issue 14 1.8 1.8 no signal
429 Chronic Sinusitis 9 1.8 1.8 no signal
430 Cardiovascular Disorder 61 1.8 1.8 no signal
431 Hepatic Necrosis 9 1.8 1.8 no signal
432 Intercepted Medication Error 11 1.8 1.8 no signal
433 Blood Count Abnormal 36 1.7 1.7 no signal
434 Pericarditis 39 1.7 1.7 no signal
435 Cardiomegaly 29 1.7 1.7 no signal
436 Streptococcal Infection 13 1.7 1.7 no signal
437 Dermatitis Exfoliative Generalised 8 1.7 1.7 no signal
438 Agranulocytosis 43 1.7 1.7 no signal
439 Pericardial Effusion 53 1.7 1.7 no signal
440 Angiopathy 13 1.7 1.7 no signal
441 Aortic Stenosis 8 1.7 1.7 no signal
442 Neurological Symptom 13 1.7 1.7 no signal
443 Blepharitis 9 1.7 1.7 no signal
444 Gastroenteritis 33 1.7 1.7 no signal
445 Abdominal Abscess 10 1.7 1.7 no signal
446 Subarachnoid Haemorrhage 23 1.7 1.7 no signal
447 Epstein-barr Virus Infection 14 1.7 1.7 no signal
448 Meningitis 15 1.7 1.7 no signal
449 Ischaemic Stroke 40 1.7 1.7 no signal
450 Dyspnoea Exertional 84 1.7 1.7 no signal
451 Papilloedema 10 1.6 1.6 no signal
452 Immune System Disorder 29 1.6 1.6 no signal
453 Intentional Product Use Issue 193 1.6 1.6 no signal
454 Therapeutic Product Effect Incomplete 155 1.6 1.6 no signal
455 Electrolyte Imbalance 25 1.6 1.6 no signal
456 Thrombosis 175 1.6 1.6 no signal
457 Osteonecrosis Of Jaw 54 1.6 1.6 no signal
458 Red Cell Distribution Width Increased 9 1.6 1.6 no signal
459 Performance Status Decreased 10 1.6 1.6 no signal
460 Bronchitis 159 1.6 1.6 no signal
461 Diverticulitis 59 1.6 1.6 no signal
462 Lung Disorder 104 1.6 1.6 no signal
463 Mental Status Changes 59 1.6 1.6 no signal
464 Myocarditis 24 1.6 1.6 no signal
465 Dialysis 30 1.6 1.6 no signal
466 Viral Infection 70 1.6 1.6 no signal
467 Serum Ferritin Increased 11 1.6 1.6 no signal
468 Full Blood Count Abnormal 22 1.6 1.6 no signal
469 Tumour Marker Increased 10 1.6 1.6 no signal
470 Metabolic Disorder 12 1.5 1.5 no signal
471 Blood Test Abnormal 29 1.5 1.5 no signal
472 General Physical Condition Abnormal 14 1.5 1.5 no signal
473 Death 1,763 1.5 1.6 no signal
474 Decreased Immune Responsiveness 20 1.5 1.5 no signal
475 Rib Fracture 42 1.5 1.5 no signal
476 Renal Tubular Necrosis 20 1.5 1.5 no signal
477 Syncope 203 1.5 1.5 no signal
478 Iron Deficiency 9 1.5 1.5 no signal
479 Liver Function Test Increased 43 1.5 1.5 no signal
480 Mass 28 1.5 1.5 no signal
481 Azotaemia 8 1.5 1.5 no signal
482 Bacterial Infection 37 1.5 1.5 no signal
483 Fatigue 1,542 1.5 1.5 no signal
484 Cellulitis 100 1.5 1.5 no signal
485 Dyspnoea 1,117 1.5 1.5 no signal
486 Skin Infection 22 1.5 1.5 no signal
487 Spinal Fracture 39 1.5 1.5 no signal
488 Atrioventricular Block Complete 13 1.5 1.5 no signal
489 Angina Pectoris 56 1.4 1.4 no signal
490 Hyperbilirubinaemia 20 1.4 1.4 no signal
491 Ventricular Tachycardia 32 1.4 1.4 no signal
492 Gastrointestinal Inflammation 15 1.4 1.4 no signal
493 Enterocolitis 11 1.4 1.4 no signal
494 Oral Candidiasis 25 1.4 1.4 no signal
495 Transfusion 20 1.4 1.4 no signal
496 Asthenia 710 1.4 1.4 no signal
497 Hypertriglyceridaemia 11 1.4 1.4 no signal
498 Hypovolaemia 11 1.4 1.4 no signal
499 General Physical Health Deterioration 214 1.4 1.4 no signal
500 Blood Bilirubin Increased 50 1.4 1.4 no signal
501 Tooth Disorder 41 1.4 1.4 no signal
502 Organising Pneumonia 9 1.4 1.4 no signal
503 Bone Cancer 8 1.4 1.4 no signal
504 Hepatocellular Injury 26 1.4 1.4 no signal
505 Drug Intolerance 175 1.4 1.4 no signal
506 Blood Pressure Abnormal 36 1.4 1.4 no signal
507 Arteriosclerosis Coronary Artery 12 1.4 1.4 no signal
508 Staphylococcal Sepsis 9 1.4 1.4 no signal
509 Nephropathy 17 1.4 1.4 no signal
510 Oedema 98 1.4 1.4 no signal
511 Subdural Haematoma 26 1.4 1.4 no signal
512 Hyperkalaemia 63 1.3 1.3 no signal
513 Diverticulum 13 1.3 1.3 no signal
514 Haemorrhage Intracranial 27 1.3 1.3 no signal
515 Candida Infection 30 1.3 1.3 no signal
516 Coronary Artery Stenosis 9 1.3 1.3 no signal
517 Immunodeficiency 26 1.3 1.3 no signal
518 Cognitive Disorder 82 1.3 1.3 no signal
519 Haemoptysis 49 1.3 1.3 no signal
520 Oedema Peripheral 214 1.3 1.3 no signal
521 Transplant Rejection 14 1.3 1.3 no signal
522 Diarrhoea 1,123 1.3 1.3 no signal
523 Iron Deficiency Anaemia 16 1.3 1.3 no signal
524 Dehydration 232 1.3 1.3 no signal
525 Urinary Tract Infection 293 1.3 1.3 no signal
526 Transient Ischaemic Attack 58 1.3 1.3 no signal
527 Hepatitis Acute 11 1.3 1.3 no signal
528 Colitis 64 1.3 1.3 no signal
529 Purpura 15 1.3 1.3 no signal
530 Epistaxis 127 1.3 1.3 no signal
531 Cholecystitis 20 1.3 1.3 no signal
532 Toxic Skin Eruption 17 1.3 1.3 no signal
533 Cholestasis 32 1.2 1.3 no signal
534 Chronic Obstructive Pulmonary Disease 87 1.2 1.2 no signal
535 Hepatitis Cholestatic 10 1.2 1.2 no signal
536 Tachycardia 148 1.2 1.2 no signal
537 Chills 195 1.2 1.2 no signal
538 Haemodialysis 14 1.2 1.2 no signal
539 Sars-cov-2 Test Positive 22 1.2 1.2 no signal
540 Night Sweats 53 1.2 1.2 no signal
541 Hyponatraemia 92 1.2 1.2 no signal
542 Disseminated Intravascular Coagulation 23 1.2 1.2 no signal
543 Nervous System Disorder 51 1.2 1.2 no signal
544 Ileus 20 1.2 1.2 no signal
545 Splenomegaly 19 1.2 1.2 no signal
546 Constipation 351 1.2 1.2 no signal
547 Oliguria 10 1.2 1.2 no signal
548 Leukocytosis 29 1.2 1.2 no signal
549 Urine Output Decreased 14 1.2 1.2 no signal
550 Infarction 11 1.2 1.2 no signal
551 Arteriosclerosis 15 1.2 1.2 no signal
552 Drug Eruption 28 1.2 1.2 no signal
553 Herpes Zoster 91 1.2 1.2 no signal
554 Spinal Disorder 15 1.2 1.2 no signal
555 Cardio-respiratory Arrest 66 1.2 1.2 no signal
556 Granulocytopenia 9 1.2 1.2 no signal
557 Cardiac Valve Disease 9 1.2 1.2 no signal
558 Blood Uric Acid Increased 9 1.2 1.2 no signal
559 Cardiac Arrest 129 1.2 1.2 no signal
560 Fluid Retention 79 1.2 1.2 no signal
561 Vasculitis 18 1.2 1.2 no signal
562 Decreased Appetite 356 1.1 1.1 no signal
563 No Therapeutic Response 19 1.1 1.1 no signal
564 Liver Disorder 68 1.1 1.1 no signal
565 Metastasis 11 1.1 1.1 no signal
566 Drug Reaction With Eosinophilia And Systemic Symptoms 39 1.1 1.1 no signal
567 Lower Respiratory Tract Infection 69 1.1 1.1 no signal
568 Malignant Neoplasm Progression 155 1.1 1.1 no signal
569 Neoplasm Progression 53 1.1 1.1 no signal
570 Hyperlipidaemia 18 1.1 1.1 no signal
571 Toxicity To Various Agents 252 1.1 1.1 no signal
572 Mouth Haemorrhage 11 1.1 1.1 no signal
573 Terminal State 10 1.1 1.1 no signal
574 Shock 34 1.1 1.1 no signal
575 Leukaemia 14 1.1 1.1 no signal
576 Adverse Drug Reaction 132 1.1 1.1 no signal
577 Basal Cell Carcinoma 23 1.1 1.1 no signal
578 Acute Hepatic Failure 20 1.1 1.1 no signal
579 Back Pain 341 1.1 1.1 no signal
580 Pulmonary Thrombosis 16 1.1 1.1 no signal
581 Ascites 43 1.1 1.1 no signal
582 Cholangitis 9 1.1 1.1 no signal
583 Delirium 50 1.1 1.1 no signal
584 Coagulopathy 24 1.1 1.1 no signal
585 Neuralgia 35 1.1 1.1 no signal
586 Transaminases Increased 32 1.1 1.1 no signal
587 Confusional State 233 1.1 1.1 no signal
588 Cataract 85 1.1 1.1 no signal
589 Blood Potassium Decreased 43 1.1 1.1 no signal
590 Chronic Kidney Disease 108 1.1 1.1 no signal
591 Appendicitis 13 1.0 1.0 no signal
592 Pyelonephritis 12 1.0 1.0 no signal
593 Gastrointestinal Disorder 123 1.0 1.0 no signal
594 Angina Unstable 9 1.0 1.0 no signal
595 Nausea 1,082 1.0 1.0 no signal
596 Shock Haemorrhagic 11 1.0 1.0 no signal
597 Gamma-glutamyltransferase Increased 30 1.0 1.0 no signal
598 Muscle Atrophy 17 1.0 1.0 no signal
599 Hepatic Function Abnormal 50 1.0 1.0 no signal
600 Diplopia 35 1.0 1.0 no signal
601 Ventricular Extrasystoles 14 1.0 1.0 no signal
602 Muscle Spasms 245 1.0 1.0 no signal
603 Hypoacusis 57 1.0 1.0 no signal
604 Aphasia 40 1.0 1.0 no signal
605 Body Temperature Increased 27 1.0 1.0 no signal
606 Acidosis 10 1.0 1.0 no signal
607 Cough 364 1.0 1.0 no signal
608 Large Intestine Perforation 9 1.0 1.0 no signal
609 Femur Fracture 40 1.0 1.0 no signal
610 Pneumonia Aspiration 32 1.0 1.0 no signal
611 Drug Effect Incomplete 47 1.0 1.0 no signal
612 Brain Oedema 16 0.9 0.9 no signal
613 Chest Pain 233 0.9 0.9 no signal
614 Hospitalisation 191 0.9 0.9 no signal
615 Taste Disorder 25 0.9 0.9 no signal
616 Intestinal Perforation 14 0.9 0.9 no signal
617 Interstitial Lung Disease 60 0.9 0.9 no signal
618 Rhinitis 10 0.9 0.9 no signal
619 Face Oedema 21 0.9 0.9 no signal
620 Staphylococcal Infection 41 0.9 0.9 no signal
621 Respiratory Disorder 37 0.9 0.9 no signal
622 Bradycardia 65 0.9 0.9 no signal
623 Alanine Aminotransferase Increased 75 0.9 0.9 no signal
624 Disease Recurrence 58 0.9 0.9 no signal
625 Fracture 23 0.9 0.9 no signal
626 Lower Gastrointestinal Haemorrhage 9 0.9 0.9 no signal
627 Skin Lesion 33 0.9 0.9 no signal
628 Colon Cancer 18 0.9 0.9 no signal
629 Musculoskeletal Disorder 23 0.9 0.9 no signal
630 End Stage Renal Disease 22 0.9 0.9 no signal
631 Hypotension 237 0.9 0.9 no signal
632 Blood Pressure Increased 181 0.9 0.9 no signal
633 Lipase Increased 9 0.9 0.9 no signal
634 Diffuse Large B-cell Lymphoma 9 0.9 0.9 no signal
635 Hepatic Enzyme Increased 80 0.9 0.9 no signal
636 Hypertransaminasaemia 8 0.9 0.9 no signal
637 Therapeutic Response Decreased 70 0.9 0.9 no signal
638 Osteomyelitis 21 0.9 0.9 no signal
639 Pelvic Fracture 9 0.9 0.9 no signal
640 Insomnia 308 0.9 0.9 no signal
641 Laceration 11 0.9 0.9 no signal
642 Blood Calcium Decreased 13 0.9 0.9 no signal
643 Pulmonary Fibrosis 22 0.9 0.9 no signal
644 Haemorrhagic Stroke 9 0.9 0.9 no signal
645 Hypophagia 29 0.9 0.9 no signal
646 Small Intestinal Obstruction 14 0.9 0.9 no signal
647 Productive Cough 54 0.9 0.9 no signal
648 Vomiting 534 0.8 0.8 no signal
649 Tooth Infection 15 0.8 0.8 no signal
650 Skin Reaction 16 0.8 0.8 no signal
651 Upper Gastrointestinal Haemorrhage 19 0.8 0.8 no signal
652 Ageusia 28 0.8 0.8 no signal
653 Presyncope 27 0.8 0.8 no signal
654 Coronary Artery Disease 34 0.8 0.8 no signal
655 Dysgeusia 83 0.8 0.8 no signal
656 Laryngitis 12 0.8 0.8 no signal
657 Stomatitis 67 0.8 0.8 no signal
658 Haematocrit Decreased 22 0.8 0.8 no signal
659 Upper-airway Cough Syndrome 9 0.8 0.8 no signal
660 Orthostatic Hypotension 19 0.8 0.8 no signal
661 Chest Discomfort 111 0.8 0.8 no signal
662 Eosinophilia 19 0.8 0.8 no signal
663 Adrenal Insufficiency 13 0.8 0.8 no signal
664 Skin Disorder 36 0.8 0.8 no signal
665 Pancreatitis Acute 24 0.8 0.8 no signal
666 Peripheral Swelling 164 0.8 0.8 no signal
667 Diarrhoea Haemorrhagic 10 0.8 0.8 no signal
668 Altered State Of Consciousness 23 0.8 0.8 no signal
669 Facial Paralysis 9 0.8 0.8 no signal
670 Proteinuria 20 0.8 0.8 no signal
671 Liver Function Test Abnormal 31 0.8 0.8 no signal
672 Myocardial Infarction 186 0.8 0.8 no signal
673 Rash Pruritic 57 0.8 0.8 no signal
674 Nasopharyngitis 195 0.8 0.8 no signal
675 Hepatitis 27 0.8 0.8 no signal
676 Hypersomnia 30 0.8 0.8 no signal
677 Sleep Disorder 73 0.8 0.8 no signal
678 Cerebral Haemorrhage 37 0.8 0.8 no signal
679 Rash 444 0.8 0.8 no signal
680 Treatment Failure 84 0.8 0.8 no signal
681 Cerebral Infarction 25 0.8 0.8 no signal
682 Spinal Osteoarthritis 9 0.8 0.8 no signal
683 Blood Albumin Decreased 8 0.8 0.8 no signal
684 Metabolic Acidosis 32 0.8 0.8 no signal
685 Sciatica 16 0.8 0.8 no signal
686 Drug-induced Liver Injury 31 0.7 0.7 no signal
687 Blood Alkaline Phosphatase Increased 25 0.7 0.7 no signal
688 Aspartate Aminotransferase Increased 53 0.7 0.7 no signal
689 Hip Fracture 32 0.7 0.7 no signal
690 Gastroenteritis Viral 18 0.7 0.7 no signal
691 Malaise 436 0.7 0.7 no signal
692 Localised Infection 24 0.7 0.7 no signal
693 Ear Infection 26 0.7 0.7 no signal
694 Hepatic Steatosis 18 0.7 0.7 no signal
695 Hepatic Cirrhosis 18 0.7 0.7 no signal
696 Flank Pain 9 0.7 0.7 no signal
697 Weight Fluctuation 10 0.7 0.7 no signal
698 Drug Effective For Unapproved Indication 28 0.7 0.7 no signal
699 Rectal Haemorrhage 41 0.7 0.7 no signal
700 Gallbladder Disorder 17 0.7 0.7 no signal
701 Musculoskeletal Pain 50 0.7 0.7 no signal
702 Eyelid Oedema 11 0.7 0.7 no signal
703 Depressed Level Of Consciousness 37 0.7 0.7 no signal
704 Unresponsive To Stimuli 24 0.7 0.7 no signal
705 Urinary Retention 31 0.7 0.7 no signal
706 Toxic Epidermal Necrolysis 14 0.7 0.7 no signal
707 Hepatic Failure 28 0.7 0.7 no signal
708 Skin Laceration 10 0.7 0.7 no signal
709 Conjunctivitis 17 0.7 0.7 no signal
710 Body Height Decreased 10 0.7 0.7 no signal
711 Mobility Decreased 66 0.7 0.7 no signal
712 Oesophagitis 10 0.7 0.7 no signal
713 Bedridden 12 0.7 0.7 no signal
714 Gastritis 24 0.7 0.7 no signal
715 White Blood Cell Count Increased 35 0.7 0.7 no signal
716 Tooth Fracture 10 0.7 0.7 no signal
717 Weight Decreased 253 0.7 0.7 no signal
718 Local Swelling 16 0.7 0.7 no signal
719 Fungal Infection 30 0.7 0.7 no signal
720 Upper Limb Fracture 18 0.7 0.7 no signal
721 Drug Effect Decreased 49 0.7 0.7 no signal
722 Blood Urea Increased 15 0.7 0.7 no signal
723 Muscular Weakness 101 0.7 0.7 no signal
724 Sinus Congestion 12 0.7 0.7 no signal
725 Lethargy 51 0.7 0.7 no signal
726 Toothache 16 0.7 0.7 no signal
727 Tremor 147 0.7 0.7 no signal
728 Status Epilepticus 10 0.7 0.7 no signal
729 Influenza Like Illness 73 0.7 0.7 no signal
730 Pharyngitis 11 0.7 0.7 no signal
731 Tooth Abscess 9 0.7 0.7 no signal
732 Palpitations 103 0.7 0.7 no signal
733 Gastrointestinal Haemorrhage 74 0.7 0.7 no signal
734 Drug Ineffective For Unapproved Indication 49 0.7 0.7 no signal
735 Circulatory Collapse 15 0.7 0.7 no signal
736 Sinusitis 90 0.7 0.7 no signal
737 Musculoskeletal Discomfort 15 0.6 0.6 no signal
738 Poor Venous Access 9 0.6 0.6 no signal
739 Liver Injury 21 0.6 0.6 no signal
740 Nerve Compression 8 0.6 0.6 no signal
741 Blood Potassium Increased 14 0.6 0.6 no signal
742 Dementia 24 0.6 0.6 no signal
743 Oxygen Saturation Decreased 48 0.6 0.6 no signal
744 C-reactive Protein Increased 31 0.6 0.6 no signal
745 Epilepsy 26 0.6 0.6 no signal
746 Activities Of Daily Living Impaired 17 0.6 0.6 no signal
747 Bronchospasm 12 0.6 0.6 no signal
748 Renal Injury 25 0.6 0.6 no signal
749 Feeling Abnormal 200 0.6 0.6 no signal
750 Glomerular Filtration Rate Decreased 10 0.6 0.6 no signal
751 Vitamin D Deficiency 8 0.6 0.6 no signal
752 Jaundice 22 0.6 0.6 no signal
753 Dental Caries 9 0.6 0.6 no signal
754 Disturbance In Attention 44 0.6 0.6 no signal
755 Cystitis 26 0.6 0.6 no signal
756 Renal Failure Acute 35 0.6 0.6 no signal
757 Ventricular Fibrillation 9 0.6 0.6 no signal
758 Sinus Disorder 16 0.6 0.6 no signal
759 Visual Acuity Reduced 27 0.6 0.6 no signal
760 Cerebrovascular Accident 137 0.6 0.6 no signal
761 Eye Infection 9 0.6 0.6 no signal
762 Blood Sodium Decreased 15 0.6 0.6 no signal
763 Hypoaesthesia Oral 12 0.6 0.6 no signal
764 Central Nervous System Lesion 11 0.6 0.6 no signal
765 Poor Quality Sleep 17 0.6 0.6 no signal
766 Therapeutic Product Effect Decreased 35 0.6 0.6 no signal
767 Sluggishness 8 0.6 0.6 no signal
768 Dysphonia 46 0.6 0.6 no signal
769 Accidental Exposure To Product 78 0.6 0.6 no signal
770 Glaucoma 15 0.6 0.6 no signal
771 Pain In Jaw 22 0.6 0.6 no signal
772 Hemiparesis 13 0.6 0.6 no signal
773 Dysuria 28 0.6 0.6 no signal
774 Abasia 19 0.6 0.6 no signal
775 Haematuria 26 0.6 0.6 no signal
776 Disorientation 30 0.6 0.6 no signal
777 Dyspepsia 74 0.6 0.6 no signal
778 Photophobia 14 0.6 0.6 no signal
779 Tubulointerstitial Nephritis 14 0.6 0.6 no signal
780 Thyroid Cancer 9 0.6 0.6 no signal
781 Pulmonary Mass 11 0.6 0.6 no signal
782 Eye Disorder 24 0.5 0.5 no signal
783 Coronary Artery Occlusion 10 0.5 0.5 no signal
784 Gastrooesophageal Reflux Disease 58 0.5 0.5 no signal
785 Tooth Extraction 9 0.5 0.5 no signal
786 Blood Pressure Systolic Increased 14 0.5 0.5 no signal
787 Oral Pain 16 0.5 0.5 no signal
788 Somnolence 143 0.5 0.5 no signal
789 Hypoaesthesia 106 0.5 0.5 no signal
790 Heart Rate Increased 70 0.5 0.5 no signal
791 Fall 233 0.5 0.5 no signal
792 Pancreatitis 37 0.5 0.5 no signal
793 Rotator Cuff Syndrome 9 0.5 0.5 no signal
794 Skin Cancer 15 0.5 0.5 no signal
795 Thinking Abnormal 13 0.5 0.5 no signal
796 Hypokinesia 10 0.5 0.5 no signal
797 Rash Generalised 18 0.5 0.5 no signal
798 Ear Discomfort 7 0.5 0.5 no signal
799 Pain In Extremity 201 0.5 0.5 no signal
800 Melaena 15 0.5 0.5 no signal
801 Lung Neoplasm Malignant 28 0.5 0.5 no signal
802 Discomfort 41 0.5 0.5 no signal
803 Ill-defined Disorder 41 0.5 0.5 no signal
804 Back Disorder 11 0.5 0.5 no signal
805 Anaphylactic Reaction 37 0.5 0.5 no signal
806 Abdominal Distension 70 0.5 0.5 no signal
807 Eye Haemorrhage 9 0.5 0.5 no signal
808 Loss Of Personal Independence In Daily Activities 32 0.5 0.5 no signal
809 Petechiae 7 0.5 0.5 no signal
810 Metastases To Bone 11 0.5 0.5 no signal
811 Ear Pain 13 0.5 0.5 no signal
812 Gout 12 0.5 0.5 no signal
813 Uveitis 9 0.5 0.5 no signal
814 Haemorrhoids 13 0.5 0.5 no signal
815 Depressed Mood 35 0.5 0.5 no signal
816 Wheezing 39 0.5 0.5 no signal
817 Vision Blurred 89 0.5 0.5 no signal
818 Drug Ineffective 854 0.5 0.5 no signal
819 Wound Infection 7 0.5 0.5 no signal
820 Erythema Multiforme 6 0.5 0.5 no signal
821 Neck Pain 36 0.5 0.5 no signal
822 Personality Change 6 0.5 0.5 no signal
823 Injection Site Extravasation 8 0.5 0.5 no signal
824 Gastrointestinal Pain 7 0.5 0.5 no signal
825 Seasonal Allergy 9 0.5 0.5 no signal
826 Swelling Face 41 0.5 0.5 no signal
827 Peritonitis 13 0.5 0.5 no signal
828 Paraesthesia Oral 9 0.5 0.5 no signal
829 Gait Disturbance 120 0.5 0.5 no signal
830 Dizziness Postural 6 0.5 0.5 no signal
831 Therapy Change 6 0.5 0.5 no signal
832 Tuberculosis 8 0.5 0.5 no signal
833 Abdominal Pain 144 0.5 0.5 no signal
834 Mental Disorder 27 0.5 0.5 no signal
835 Mouth Ulceration 13 0.5 0.5 no signal
836 Hiatus Hernia 8 0.5 0.5 no signal
837 Heart Rate Irregular 14 0.5 0.5 no signal
838 Haematoma 16 0.5 0.5 no signal
839 Neoplasm Malignant 41 0.5 0.5 no signal
840 Pain 378 0.5 0.5 no signal
841 Haemorrhage 64 0.5 0.5 no signal
842 Hepatomegaly 6 0.5 0.5 no signal
843 Treatment Noncompliance 33 0.5 0.5 no signal
844 Pelvic Pain 11 0.5 0.5 no signal
845 Restless Legs Syndrome 11 0.5 0.5 no signal
846 Multiple Fractures 10 0.4 0.4 no signal
847 Diabetes Mellitus 46 0.4 0.4 no signal
848 Ocular Hyperaemia 28 0.4 0.4 no signal
849 Dry Eye 29 0.4 0.4 no signal
850 Blood Iron Decreased 7 0.4 0.4 no signal
851 Intervertebral Disc Protrusion 13 0.4 0.4 no signal
852 Emphysema 6 0.4 0.4 no signal
853 Myoclonus 7 0.4 0.4 no signal
854 Gingival Bleeding 8 0.4 0.4 no signal
855 Oropharyngeal Pain 54 0.4 0.4 no signal
856 Contusion 56 0.4 0.4 no signal
857 Blood Pressure Fluctuation 14 0.4 0.4 no signal
858 Nasal Congestion 34 0.4 0.4 no signal
859 Peripheral Coldness 8 0.4 0.4 no signal
860 Head Injury 18 0.4 0.4 no signal
861 Headache 355 0.4 0.4 no signal
862 Secretion Discharge 7 0.4 0.4 no signal
863 Respiratory Tract Congestion 9 0.4 0.4 no signal
864 Dermatitis Allergic 7 0.4 0.4 no signal
865 Eating Disorder 12 0.4 0.4 no signal
866 Product Use In Unapproved Indication 136 0.4 0.4 no signal
867 Burning Sensation 39 0.4 0.4 no signal
868 Skin Exfoliation 46 0.4 0.4 no signal
869 Anosmia 8 0.4 0.4 no signal
870 Dizziness 274 0.4 0.4 no signal
871 Limb Discomfort 17 0.4 0.4 no signal
872 Impaired Gastric Emptying 7 0.4 0.4 no signal
873 Brain Fog 8 0.4 0.4 no signal
874 Inflammation 28 0.4 0.4 no signal
875 Memory Impairment 75 0.4 0.4 no signal
876 Balance Disorder 47 0.4 0.4 no signal
877 Skin Ulcer 14 0.4 0.4 no signal
878 Blood Glucose Abnormal 10 0.4 0.4 no signal
879 Paraesthesia 85 0.4 0.4 no signal
880 Stevens-johnson Syndrome 12 0.4 0.4 no signal
881 Mental Impairment 13 0.4 0.4 no signal
882 Hyperhidrosis 69 0.4 0.4 no signal
883 Deafness 14 0.4 0.4 no signal
884 Intestinal Obstruction 20 0.4 0.4 no signal
885 Seizure 61 0.4 0.4 no signal
886 Complication Associated With Device 7 0.4 0.4 no signal
887 Hypersensitivity 98 0.4 0.4 no signal
888 Pollakiuria 22 0.4 0.4 no signal
889 Rhinorrhoea 34 0.4 0.4 no signal
890 Foot Fracture 10 0.4 0.4 no signal
891 Nephrolithiasis 24 0.4 0.4 no signal
892 Cholelithiasis 17 0.4 0.4 no signal
893 Gastric Haemorrhage 6 0.4 0.4 no signal
894 Lymphoma 8 0.4 0.4 no signal
895 Ankle Fracture 8 0.4 0.4 no signal
896 Vitreous Floaters 5 0.4 0.4 no signal
897 Haematemesis 13 0.4 0.4 no signal
898 Head Discomfort 9 0.4 0.4 no signal
899 Kidney Infection 10 0.4 0.4 no signal
900 Anaphylactic Shock 13 0.4 0.4 no signal
901 Urinary Incontinence 15 0.4 0.4 no signal
902 Dry Mouth 41 0.4 0.4 no signal
903 Myalgia 86 0.4 0.4 no signal
904 Abdominal Discomfort 84 0.4 0.4 no signal
905 Aphonia 7 0.4 0.4 no signal
906 Abscess 8 0.4 0.4 no signal
907 Tinnitus 23 0.4 0.4 no signal
908 Hypotonia 5 0.4 0.4 no signal
909 Osteoarthritis 21 0.4 0.4 no signal
910 Therapy Interrupted 34 0.4 0.4 no signal
911 Dry Throat 5 0.4 0.4 no signal
912 Chromaturia 11 0.4 0.4 no signal
913 Euphoric Mood 5 0.4 0.4 no signal
914 Inappropriate Schedule Of Drug Administration 35 0.4 0.4 no signal
915 Folliculitis 5 0.4 0.4 no signal
916 Hyperthyroidism 7 0.4 0.4 no signal
917 Dermatitis 10 0.4 0.4 no signal
918 Swelling 45 0.4 0.4 no signal
919 Heart Rate Decreased 17 0.4 0.4 no signal
920 Limb Injury 13 0.4 0.4 no signal
921 Type 2 Diabetes Mellitus 16 0.4 0.4 no signal
922 Renal Pain 5 0.4 0.4 no signal
923 Asthma 53 0.4 0.4 no signal
924 Feeling Jittery 9 0.4 0.4 no signal
925 Lower Limb Fracture 9 0.4 0.4 no signal
926 Lacrimation Increased 14 0.3 0.3 no signal
927 Loss Of Consciousness 60 0.3 0.3 no signal
928 Hernia 9 0.3 0.3 no signal
929 Blood Pressure Decreased 31 0.3 0.3 no signal
930 Flushing 47 0.3 0.3 no signal
931 Eye Swelling 17 0.3 0.3 no signal
932 Metastases To Liver 8 0.3 0.3 no signal
933 Multi-organ Failure 8 0.3 0.3 no signal
934 Pruritus Generalised 10 0.3 0.3 no signal
935 Cold Sweat 8 0.3 0.3 no signal
936 Lymphadenopathy 16 0.3 0.3 no signal
937 Blood Triglycerides Increased 8 0.3 0.3 no signal
938 Nerve Injury 5 0.3 0.3 no signal
939 Visual Impairment 55 0.3 0.3 no signal
940 Rash Papular 10 0.3 0.3 no signal
941 Cyanosis 7 0.3 0.3 no signal
942 Pallor 12 0.3 0.3 no signal
943 Impaired Driving Ability 5 0.3 0.3 no signal
944 Aggression 22 0.3 0.3 no signal
945 Illness 44 0.3 0.3 no signal
946 Retinal Detachment 4 0.3 0.3 no signal
947 Wound 12 0.3 0.3 no signal
948 Weight Increased 96 0.3 0.3 no signal
949 Increased Appetite 8 0.3 0.3 no signal
950 Drug Effect Less Than Expected 6 0.3 0.3 no signal
951 Joint Swelling 51 0.3 0.3 no signal
952 Retching 9 0.3 0.3 no signal
953 Gait Inability 14 0.3 0.3 no signal
954 Psychomotor Hyperactivity 7 0.3 0.3 no signal
955 Erythema 85 0.3 0.3 no signal
956 Skin Discolouration 19 0.3 0.3 no signal
957 Blood Glucose Increased 78 0.3 0.3 no signal
958 Parkinsonism 4 0.3 0.3 no signal
959 Hepatitis C 5 0.3 0.3 no signal
960 Hypothyroidism 13 0.3 0.3 no signal
961 Arthralgia 167 0.3 0.3 no signal
962 Feeding Disorder 8 0.3 0.3 no signal
963 Salivary Hypersecretion 4 0.3 0.3 no signal
964 Haematochezia 22 0.3 0.3 no signal
965 Depression 91 0.3 0.3 no signal
966 Injection Site Irritation 5 0.3 0.3 no signal
967 Hypothermia 4 0.3 0.3 no signal
968 Vertigo 24 0.3 0.3 no signal
969 Arthritis 31 0.3 0.3 no signal
970 Eyelid Ptosis 4 0.3 0.3 no signal
971 Blindness 16 0.3 0.3 no signal
972 Flatulence 22 0.3 0.3 no signal
973 Urticaria 64 0.3 0.3 no signal
974 Rash Erythematous 18 0.3 0.3 no signal
975 Nodule 5 0.3 0.3 no signal
976 Nervousness 20 0.3 0.3 no signal
977 Throat Irritation 17 0.3 0.3 no signal
978 Arthropathy 21 0.3 0.3 no signal
979 Abdominal Pain Upper 77 0.3 0.3 no signal
980 Hunger 5 0.3 0.3 no signal
981 Pruritus 140 0.3 0.3 no signal
982 Dysphagia 35 0.3 0.3 no signal
983 Pharyngitis Streptococcal 4 0.3 0.3 no signal
984 Product Use Issue 69 0.3 0.3 no signal
985 Condition Aggravated 111 0.3 0.3 no signal
986 Amnesia 24 0.3 0.3 no signal
987 Osteonecrosis 12 0.3 0.3 no signal
988 Oral Herpes 7 0.3 0.3 no signal
989 Therapeutic Response Unexpected 16 0.3 0.3 no signal
990 Restlessness 13 0.3 0.3 no signal
991 Anxiety 100 0.3 0.3 no signal
992 Hypoglycaemia 17 0.3 0.3 no signal
993 Skin Haemorrhage 5 0.3 0.3 no signal
994 Hot Flush 26 0.3 0.3 no signal
995 Gastric Disorder 12 0.3 0.3 no signal
996 Eye Pain 19 0.3 0.3 no signal
997 Feeling Hot 21 0.3 0.3 no signal
998 Dysstasia 10 0.3 0.3 no signal
999 Tooth Loss 7 0.2 0.2 no signal
1000 Increased Tendency To Bruise 3 0.2 0.2 no signal
1001 Feeling Cold 9 0.2 0.2 no signal
1002 Blood Cholesterol Increased 15 0.2 0.2 no signal
1003 Pharyngeal Oedema 5 0.2 0.2 no signal
1004 Hair Colour Changes 4 0.2 0.2 no signal
1005 Product Dose Omission 21 0.2 0.2 no signal
1006 Agitation 23 0.2 0.2 no signal
1007 Intraocular Pressure Increased 4 0.2 0.2 no signal
1008 Road Traffic Accident 13 0.2 0.2 no signal
1009 Sleep Disorder Due To A General Medical Condition 5 0.2 0.2 no signal
1010 Eczema 15 0.2 0.2 no signal
1011 Stress 21 0.2 0.2 no signal
1012 Osteoporosis 12 0.2 0.2 no signal
1013 Drug Dose Omission 48 0.2 0.2 no signal
1014 Speech Disorder 15 0.2 0.2 no signal
1015 Mood Swings 9 0.2 0.2 no signal
1016 Breast Cancer Metastatic 3 0.2 0.2 no signal
1017 Coma 13 0.2 0.2 no signal
1018 Erectile Dysfunction 7 0.2 0.2 no signal
1019 Meningioma 4 0.2 0.2 no signal
1020 Psychotic Disorder 8 0.2 0.2 no signal
1021 Hallucination 20 0.2 0.2 no signal
1022 Fistula 3 0.2 0.2 no signal
1023 Irritability 16 0.2 0.2 no signal
1024 Rebound Effect 3 0.2 0.2 no signal
1025 Metastases To Lung 3 0.2 0.2 no signal
1026 Product Physical Issue 5 0.2 0.2 no signal
1027 Blister 14 0.2 0.2 no signal
1028 Angioedema 11 0.2 0.2 no signal
1029 Prostate Cancer 20 0.2 0.2 no signal
1030 Impaired Healing 8 0.2 0.2 no signal
1031 Eye Pruritus 8 0.2 0.2 no signal
1032 Dysarthria 9 0.2 0.2 no signal
1033 Product Dose Omission Issue 68 0.2 0.2 no signal
1034 Poisoning 3 0.2 0.2 no signal
1035 Anger 8 0.2 0.2 no signal
1036 Metastases To Central Nervous System 3 0.2 0.2 no signal
1037 Alopecia 46 0.2 0.2 no signal
1038 Drug Interaction 36 0.2 0.2 no signal
1039 Incorrect Product Storage 3 0.2 0.2 no signal
1040 Surgery 13 0.2 0.2 no signal
1041 Hair Texture Abnormal 3 0.2 0.2 no signal
1042 Pain Of Skin 6 0.2 0.2 no signal
1043 Incorrect Route Of Drug Administration 8 0.2 0.2 no signal
1044 Prostatic Specific Antigen Increased 3 0.2 0.2 no signal
1045 Rhabdomyolysis 9 0.2 0.2 no signal
1046 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.2 0.2 no signal
1047 Migraine 20 0.2 0.2 no signal
1048 Blood Glucose Decreased 10 0.2 0.2 no signal
1049 Pancreatic Carcinoma 6 0.2 0.2 no signal
1050 Wrong Technique In Product Usage Process 41 0.2 0.1 no signal
1051 Extra Dose Administered 8 0.1 0.1 no signal
1052 Drug Hypersensitivity 38 0.1 0.1 no signal
1053 Gastric Cancer 5 0.1 0.1 no signal
1054 Intentional Product Misuse 16 0.1 0.1 no signal
1055 Therapy Cessation 9 0.1 0.1 no signal
1056 Musculoskeletal Stiffness 15 0.1 0.1 no signal
1057 Breast Cancer 16 0.1 0.1 no signal
1058 Hepatic Cancer 4 0.1 0.1 no signal
1059 Eye Irritation 9 0.1 0.1 no signal
1060 Dry Skin 21 0.1 0.1 no signal
1061 Skin Burning Sensation 11 0.1 0.1 no signal
1062 Psoriasis 20 0.1 0.1 no signal
1063 Overdose 33 0.1 0.1 no signal
1064 Injury 10 0.1 0.1 no signal
1065 No Adverse Event 25 0.1 0.1 no signal
1066 Incorrect Drug Administration Duration 4 0.1 0.1 no signal
1067 Convulsion 8 0.1 0.1 no signal
1068 Bladder Cancer 8 0.1 0.1 no signal
1069 Colorectal Cancer 6 0.1 0.1 no signal
1070 Inappropriate Schedule Of Product Administration 20 0.1 0.1 no signal
1071 Breast Cancer Female 3 0.1 0.1 no signal
1072 Oesophageal Carcinoma 3 0.1 0.1 no signal
1073 Incorrect Dose Administered 22 0.1 0.1 no signal
1074 Injection Site Erythema 10 0.1 0.1 no signal
1075 Emotional Distress 9 0.1 0.1 no signal
1076 Injection Site Pain 21 0.1 0.1 no signal